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<script type="text/javascript" src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.boots.min.js"> </script><title>Breast Cancer - NCBI Bookshelf</title>
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<meta name="author" content="Harvey N. Mayrovitz">
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<meta name="citation_title" content="Breast Cancer">
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<meta name="citation_publisher" content="Exon Publications">
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<meta name="citation_date" content="2022/08/06">
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<meta name="citation_author" content="Harvey N. Mayrovitz">
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<meta name="citation_pmid" content="36121977">
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<meta name="citation_doi" content="10.36255/exon-publications-breast-cancer">
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<meta name="DC.Title" content="Breast Cancer">
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<meta name="DC.Contributor" content="Harvey N. Mayrovitz">
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<meta name="description" content="Breast cancer has become the most diagnosed cancer globally, surpassing lung and prostate cancers. In 2020, 2.3 million females were diagnosed with breast cancer worldwide. The incidence and related mortality from breast cancer continue to grow despite remarkable advances in our understanding of the biology of breast cancer and the availability of better therapeutic options. Therapies currently used to treat metastatic breast cancer extend the survival and quality of life of patients, but they are not curative. Therefore, a better understanding of the mechanisms involved in metastatic dissemination is of pivotal importance. This book provides a unique blend of carefully presented and structured information covering a broad array of relevant breast cancer-related issues. The first eight chapters cover breast cancer epidemiology, etiology, subtypes, current and emerging surgical innovations to treat and image breast cancer, a description of noninvasive lymphedema assessment methods to detect and track this important treatment complication, and the potential role of platelets and galectins in breast cancer metastasis. The last five chapters are devoted to the description of forward-looking albeit potential breast cancer treatment possibilities. In this regard, different chapters of the book describe novel research on the potential of ubiquitin-specific protease 18 (USP-18), ribosomal protein S6 kinase 1 (RPS6K1), the lysosomal system, nanoparticles, and proteolysis target chimeras as therapeutic agents for breast cancer. The range of clinical and translational research of breast cancer presented in this book will be of interest to healthcare professionals, clinicians, and basic scientists.">
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<meta name="og:title" content="Breast Cancer">
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<meta name="og:description" content="Breast cancer has become the most diagnosed cancer globally, surpassing lung and prostate cancers. In 2020, 2.3 million females were diagnosed with breast cancer worldwide. The incidence and related mortality from breast cancer continue to grow despite remarkable advances in our understanding of the biology of breast cancer and the availability of better therapeutic options. Therapies currently used to treat metastatic breast cancer extend the survival and quality of life of patients, but they are not curative. Therefore, a better understanding of the mechanisms involved in metastatic dissemination is of pivotal importance. This book provides a unique blend of carefully presented and structured information covering a broad array of relevant breast cancer-related issues. The first eight chapters cover breast cancer epidemiology, etiology, subtypes, current and emerging surgical innovations to treat and image breast cancer, a description of noninvasive lymphedema assessment methods to detect and track this important treatment complication, and the potential role of platelets and galectins in breast cancer metastasis. The last five chapters are devoted to the description of forward-looking albeit potential breast cancer treatment possibilities. In this regard, different chapters of the book describe novel research on the potential of ubiquitin-specific protease 18 (USP-18), ribosomal protein S6 kinase 1 (RPS6K1), the lysosomal system, nanoparticles, and proteolysis target chimeras as therapeutic agents for breast cancer. The range of clinical and translational research of breast cancer presented in this book will be of interest to healthcare professionals, clinicians, and basic scientists.">
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id="_NBK583818_"><span itemprop="name">Breast Cancer</span></h1><p class="contrib-group"><h4>Editors</h4>Editor: <span itemprop="editor">Harvey N. Mayrovitz</span>, PhD<sup>1</sup>.</p><h4>Affiliations</h4><div class="affiliation"><sup>1</sup> Department of Medical Education, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, FL, USA</div><div class="half_rhythm">Brisbane (AU): <a href="https://exonpublications.com/index.php/exon" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=publisher"><span itemprop="publisher">Exon Publications</span></a>; <span itemprop="datePublished">2022 Aug 6</span>.<div class="small">ISBN-13: <span itemprop="isbn">978-0-6453320-3-2</span></div></div><div><a href="/books/about/copyright/">Copyright</a>© 2022 Exon Publications.</div><a class="btn wsprkl bkr_rd" href="/books/n/cod9780645332032/fm.s1/?report=reader">Read</a></div><div class="bkr_clear"></div></div><div class="bkr_bottom_sep bkr_bottom_margin body-content whole_rhythm"><div itemprop="description"><p>Breast cancer has become the most diagnosed cancer globally, surpassing lung and prostate cancers. In 2020, 2.3 million females were diagnosed with breast cancer worldwide. The incidence and related mortality from breast cancer continue to grow despite remarkable advances in our understanding of the biology of breast cancer and the availability of better therapeutic options. Therapies currently used to treat metastatic breast cancer extend the survival and quality of life of patients, but they are not curative. Therefore, a better understanding of the mechanisms involved in metastatic dissemination is of pivotal importance. This book provides a unique blend of carefully presented and structured information covering a broad array of relevant breast cancer-related issues. The first eight chapters cover breast cancer epidemiology, etiology, subtypes, current and emerging surgical innovations to treat and image breast cancer, a description of noninvasive lymphedema assessment methods to detect and track this important treatment complication, and the potential role of platelets and galectins in breast cancer metastasis. The last five chapters are devoted to the description of forward-looking albeit potential breast cancer treatment possibilities. In this regard, different chapters of the book describe novel research on the potential of ubiquitin-specific protease 18 (USP-18), ribosomal protein S6 kinase 1 (RPS6K1), the lysosomal system, nanoparticles, and proteolysis target chimeras as therapeutic agents for breast cancer. The range of clinical and translational research of breast cancer presented in this book will be of interest to healthcare professionals, clinicians, and basic scientists.</p></div></div></div><div class="fm-sec"><div><p>Dr. Harvey N. Mayrovitz did his PhD graduate work at the University of Pennsylvania and trained at Temple University School of Medicine and the Graduate Hospital in Philadelphia and at the Medical Faculty and Hospital in Rotterdam and Delft University in the Netherlands. In 1998, after serving as the Director of Cardiovascular Research at the Miami Heart Research Institute in Miami Beach Florida, he joined Nova Southeastern University in Ft. Lauderdale Florida where he is now a professor of physiology in the Dr. Kiran C. Patel College of Allopathic Medicine in the Department of Medical Education. His teaching areas include cardiovascular and pulmonary physiology directed toward medical and graduate health-science students. His current research areas include cardiopulmonary, lymphedema, and mostly noninvasive clinical and biophysical studies for diagnosis and therapy. He has authored over 150 scientific publications in these and related areas along with multiple book chapters. He continues his research activities and student mentoring with the most current research focused on developing ways to assess and better understand processes associated with lymphedema detection, progression, and its treatment. He is also actively investigating the potential of various forms of electromagnetic energy to influence blood flow and other physiological parameters.</p></div><div><p>
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<b>Breast Cancer</b>
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</p><p>ISBN: 978-0-6453320-3-2</p><p>DOI: <a href="https://doi.org/10.36255/exon-publications-breast-cancer" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://doi.org/10.36255/exon-publications-breast-cancer</a></p><p>
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<b>Edited by</b>
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</p><p>Harvey N. Mayrovitz, PhD, Department of Medical Education, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, FL, USA</p><p>
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<b>Published by</b>
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</p><p>Exon Publications, Brisbane, Australia</p><p>
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<b>Copyright© 2022 Exon Publications</b>
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</p><p>Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). <a href="https://creativecommons.org/licenses/by-nc/4.0/" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">https://creativecommons.org/licenses/by-nc/4.0/</a>. Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, replication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.</p><p>
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<b>Notice to the user</b>
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</p><p>The views and opinions expressed in this book are believed to be accurate at the time of publication. The publisher, editors or authors cannot be held responsible or liable for any errors, omissions or consequences arising from the use of the information contained in this book. The publisher makes no warranty, implicit or explicit, with respect to the contents of this book, or its use.</p><p>First Published in August 2022</p></div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a>© 2022 Exon Publications.<p class="small">Copyright of individual chapters belongs to the respective authors. The authors grant unrestricted publishing and distribution rights to the publisher. The electronic versions of the chapters are published under Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). <a href="https://creativecommons.org/licenses/by-nc/4.0/" ref="pagearea=meta&targetsite=external&targetcat=link&targettype=uri">https://creativecommons.org/licenses/by-nc/4.0/</a>. Users are allowed to share and adapt the chapters for any non-commercial purposes as long as the authors and the publisher are explicitly identified and properly acknowledged as the original source. The book in its entirety is subject to copyright by the publisher. The reproduction, modification, replication and display of the book in its entirety, in any form, by anyone, for commercial purposes are strictly prohibited without the written consent of the publisher.</p></div><div class="small"><span class="label">Bookshelf ID: NBK583818</span><span class="label">PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/36121977" title="PubMed record of this title" ref="pagearea=meta&targetsite=entrez&targetcat=link&targettype=pubmed">36121977</a></span>DOI: <a href="http://dx.crossref.org/10.36255/exon-publications-breast-cancer" ref="pagearea=body&targetsite=external&targetcat=link&targettype=uri">10.36255/exon-publications-breast-cancer</a></div></div><div class="small-screen-prev"></div><div class="small-screen-next"></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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