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<div class="main-content lit-style"><div class="body-content whole_rhythm"><div id="ch3.appi.tab3" class="table"><h3><span class="label">Table 27</span><span class="title">Studies excluded from the health economic review</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK578045/table/ch3.appi.tab3/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch3.appi.tab3_lrgtbl__"><table><thead><tr><th id="hd_h_ch3.appi.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Reference</th><th id="hd_h_ch3.appi.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Reason for exclusion</th></tr></thead><tbody><tr><td headers="hd_h_ch3.appi.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Athanasakis 2011<a class="bk_pop" href="/books/NBK578045/#ch3.ref21" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref21/" data-bk-pop-others=""><sup>21</sup></a></td><td headers="hd_h_ch3.appi.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as partially applicable with very serious limitations because although it is comparing treatment versus no treatment in a hypertensive population, the treatment effect is based on observational systolic BPs in a treated and untreated group being put into a risk calculator as above.</td></tr><tr><td headers="hd_h_ch3.appi.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ferket 2017<a class="bk_pop" href="/books/NBK578045/#ch3.ref64" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref64/" data-bk-pop-others=""><sup>64</sup></a></td><td headers="hd_h_ch3.appi.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as not applicable because the intervention that is being compared in different CV risk subgroups is a polypill that also includes a statin.</td></tr><tr><td headers="hd_h_ch3.appi.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kypridemos 2018<a class="bk_pop" href="/books/NBK578045/#ch3.ref105" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref105/" data-bk-pop-others=""><sup>105</sup></a></td><td headers="hd_h_ch3.appi.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as not applicable because it is comparing different types of implementation of NHS health check, which can lead to identification of many conditions and not just hypertension, so it is not just about antihypertensive treatment.</td></tr><tr><td headers="hd_h_ch3.appi.tab3_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Stevanovic 2014<a class="bk_pop" href="/books/NBK578045/#ch3.ref161" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref161/" data-bk-pop-others=""><sup>161</sup></a></td><td headers="hd_h_ch3.appi.tab3_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">This study was assessed as partially applicable with very serious limitations because although it is comparing treatment versus no treatment in a hypertensive population, it uses a different risk calculator to what would be used in the UK. It also uses BP reduction for treatment effect (rather than a relative risk reduction in events) and predicts events through the calculator which should ideally be used only for baseline risks. It also has different treatment steps to UK practice.</td></tr></tbody></table></div></div></div></div>
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<div class="post-content"><div><p>From: <a href="/books/NBK578045/" target="mainwindow">Evidence review for initiating treatment</a></p><div class="iconblock clearfix ten_col"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/niceng136er3/" target="mainwindow"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-niceng136er3-lrg.png" alt="Cover of Evidence review for initiating treatment" height="100px" width="80px" /></a><div class="icnblk_cntnt"><div><div>Evidence review for initiating treatment: Hypertension in adults: diagnosis and management: Evidence review C.</div><div class="series-statement">NICE Guideline, No. 136.</div><div>National Guideline Centre (UK).</div><div>London: <a href="https://www.nice.org.uk" target="mainwindow" ref="pagearea=content-footer&targetsite=external&targetcat=link&targettype=publisher">National Institute for Health and Care Excellence (NICE)</a>; 2019 Aug.</div></div></div></div><div class="half_rhythm"><a href="/books/about/copyright/" target="mainwindow">Copyright</a> © NICE 2019.</div><p>NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div></div>
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