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<div class="main-content lit-style"><div class="body-content whole_rhythm"><div id="ch3.appi.tab1" class="table"><h3><span class="label">Table 25</span><span class="title">Studies excluded from the clinical review that were included in the previous guideline (CG127)</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK578045/table/ch3.appi.tab1/?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__ch3.appi.tab1_lrgtbl__"><table><thead><tr><th id="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Study</th><th id="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:middle;">Exclusion reason</th></tr></thead><tbody><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Arima 2006<a class="bk_pop" href="/books/NBK578045/#ch3.ref10" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref10/" data-bk-pop-others=""><sup>10</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study took place prior to 2000 date cut off</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Arima 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref11" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref11/" data-bk-pop-others=""><sup>11</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population (not treated)</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Asayama 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref17" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref17/" data-bk-pop-others=""><sup>17</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population (not hypertension), study design and analysis</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Assmann 2005<a class="bk_pop" href="/books/NBK578045/#ch3.ref20" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref20/" data-bk-pop-others=""><sup>20</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">No relevant outcomes, incorrect comparison. Prognostic study predicting cardiovascular outcomes based on pulse pressure.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Barengo 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref25" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref25/" data-bk-pop-others=""><sup>25</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison, incorrect analysis</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Barengo 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref26" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref26/" data-bk-pop-others=""><sup>26</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design, incorrect population. Population included normotensive people and compared cardiovascular risk between groups.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Benetos 2003<a class="bk_pop" href="/books/NBK578045/#ch3.ref29" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref29/" data-bk-pop-others=""><sup>29</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Comparing people with hypertension to normotensive people.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Borghi 2003<a class="bk_pop" href="/books/NBK578045/#ch3.ref35" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref35/" data-bk-pop-others=""><sup>35</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design, incorrect interventions. Not comparing treatment initiation thresholds. Study comparing link between systolic and diastolic blood pressure with cardiovascular outcomes.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Britton 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref38" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref38/" data-bk-pop-others=""><sup>38</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population; including people with heart failure</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Carlsson 2009<a class="bk_pop" href="/books/NBK578045/#ch3.ref47" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref47/" data-bk-pop-others=""><sup>47</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study took place prior to 2000 date cut off</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Conen 2007<a class="bk_pop" href="/books/NBK578045/#ch3.ref49" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref49/" data-bk-pop-others=""><sup>49</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Comparing people with hypertension to normotensive people.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Deckers 2006<a class="bk_pop" href="/books/NBK578045/#ch3.ref51" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref51/" data-bk-pop-others=""><sup>51</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fagard 2007<a class="bk_pop" href="/books/NBK578045/#ch3.ref61" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref61/" data-bk-pop-others=""><sup>61</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Study did not compare initation of treatment at different blood pressure thresholds</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fagard 2004<a class="bk_pop" href="/books/NBK578045/#ch3.ref60" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref60/" data-bk-pop-others=""><sup>60</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design. Comparing ambulatory and clinic blood pressure measurements as predictors of cardiovascular events</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fang 2006<a class="bk_pop" href="/books/NBK578045/#ch3.ref62" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref62/" data-bk-pop-others=""><sup>62</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Comparing risk of stroke in hypertensive and nomotensive people.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gustavsen 2003<a class="bk_pop" href="/books/NBK578045/#ch3.ref76" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref76/" data-bk-pop-others=""><sup>76</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population; white coat hypertension only</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Haider 2003<a class="bk_pop" href="/books/NBK578045/#ch3.ref77" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref77/" data-bk-pop-others=""><sup>77</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure, diastolic blood pressure and pulse pressure for the onset of congestive heart failure.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Head 2010<a class="bk_pop" href="/books/NBK578045/#ch3.ref80" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref80/" data-bk-pop-others=""><sup>80</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison, incorrect study design. Correlations between ambulatory and clinic blood pressure.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Inoue 2007<a class="bk_pop" href="/books/NBK578045/#ch3.ref86" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref86/" data-bk-pop-others=""><sup>86</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure amd diastolic blood pressure for predicting cardiovascular events</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ishikawa 1997<a class="bk_pop" href="/books/NBK578045/#ch3.ref89" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref89/" data-bk-pop-others=""><sup>89</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect analysis</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kagiyama 2008<a class="bk_pop" href="/books/NBK578045/#ch3.ref96" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref96/" data-bk-pop-others=""><sup>96</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study took place prior to 2000 date cut off</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kokubo 2008<a class="bk_pop" href="/books/NBK578045/#ch3.ref101" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref101/" data-bk-pop-others=""><sup>101</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kono 2005<a class="bk_pop" href="/books/NBK578045/#ch3.ref102" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref102/" data-bk-pop-others=""><sup>102</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Class comparison of different drugs, comparing the effect on cardiovascular events (case-control study).</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Kshirsagar 2006<a class="bk_pop" href="/books/NBK578045/#ch3.ref103" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref103/" data-bk-pop-others=""><sup>103</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect population. Population had a blood pressure below the diagnsotic threshold for hypertension</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Obara 2007<a class="bk_pop" href="/books/NBK578045/#ch3.ref139" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref139/" data-bk-pop-others=""><sup>139</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison. Comparing predictive value of systolic and diastolic blood pressure for cardiovascular outcomes.</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Okayama 2006<a class="bk_pop" href="/books/NBK578045/#ch3.ref143" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref143/" data-bk-pop-others=""><sup>143</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Study took place prior to 2000 date cut off. Incorrect comparison; comparing predictive value of systolic and diastolic blood pressure for cardiovascular outcomes</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Sairenchi 2005<a class="bk_pop" href="/books/NBK578045/#ch3.ref153" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref153/" data-bk-pop-others=""><sup>153</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure and diastolic blood pressure for the onset of mortality</td></tr><tr><td headers="hd_h_ch3.appi.tab1_1_1_1_1" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Weitzman 2005<a class="bk_pop" href="/books/NBK578045/#ch3.ref186" data-bk-pop-rid="/books/NBK578045/def-item/ch3.ref186/" data-bk-pop-others=""><sup>186</sup></a></td><td headers="hd_h_ch3.appi.tab1_1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Incorrect comparison, incorrect population. Comparing people with normotensive blood pressure to people with hypertension</td></tr></tbody></table></div></div></div></div>
<div class="post-content"><div><p>From: <a href="/books/NBK578045/" target="mainwindow">Evidence review for initiating treatment</a></p><div class="iconblock clearfix ten_col"><a class="img_link icnblk_img" title="Table of Contents Page" href="/books/n/niceng136er3/" target="mainwindow"><img class="source-thumb" src="/corehtml/pmc/pmcgifs/bookshelf/thumbs/th-niceng136er3-lrg.png" alt="Cover of Evidence review for initiating treatment" height="100px" width="80px" /></a><div class="icnblk_cntnt"><div><div>Evidence review for initiating treatment: Hypertension in adults: diagnosis and management: Evidence review C.</div><div class="series-statement">NICE Guideline, No. 136.</div><div>National Guideline Centre (UK).</div><div>London: <a href="https://www.nice.org.uk" target="mainwindow" ref="pagearea=content-footer&amp;targetsite=external&amp;targetcat=link&amp;targettype=publisher">National Institute for Health and Care Excellence (NICE)</a>; 2019 Aug.</div></div></div></div><div class="half_rhythm"><a href="/books/about/copyright/" target="mainwindow">Copyright</a> © NICE 2019.</div><p>NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.</p></div></div>
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