| Study | Exclusion reason |
|---|---|
| Arima 200610 | Study took place prior to 2000 date cut off |
| Arima 200911 | Incorrect population (not treated) |
| Asayama 200917 | Incorrect population (not hypertension), study design and analysis |
| Assmann 200520 | No relevant outcomes, incorrect comparison. Prognostic study predicting cardiovascular outcomes based on pulse pressure. |
| Barengo 200925 | Incorrect comparison, incorrect analysis |
| Barengo 200926 | Incorrect study design, incorrect population. Population included normotensive people and compared cardiovascular risk between groups. |
| Benetos 200329 | Incorrect comparison. Comparing people with hypertension to normotensive people. |
| Borghi 200335 | Incorrect study design, incorrect interventions. Not comparing treatment initiation thresholds. Study comparing link between systolic and diastolic blood pressure with cardiovascular outcomes. |
| Britton 200938 | Incorrect population; including people with heart failure |
| Carlsson 200947 | Study took place prior to 2000 date cut off |
| Conen 200749 | Incorrect comparison. Comparing people with hypertension to normotensive people. |
| Deckers 200651 | Incorrect population |
| Fagard 200761 | Incorrect comparison. Study did not compare initation of treatment at different blood pressure thresholds |
| Fagard 200460 | Incorrect study design. Comparing ambulatory and clinic blood pressure measurements as predictors of cardiovascular events |
| Fang 200662 | Incorrect comparison. Comparing risk of stroke in hypertensive and nomotensive people. |
| Gustavsen 200376 | Incorrect population; white coat hypertension only |
| Haider 200377 | Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure, diastolic blood pressure and pulse pressure for the onset of congestive heart failure. |
| Head 201080 | Incorrect comparison, incorrect study design. Correlations between ambulatory and clinic blood pressure. |
| Inoue 200786 | Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure amd diastolic blood pressure for predicting cardiovascular events |
| Ishikawa 199789 | Incorrect analysis |
| Kagiyama 200896 | Study took place prior to 2000 date cut off |
| Kokubo 2008101 | Incorrect comparison |
| Kono 2005102 | Incorrect comparison. Class comparison of different drugs, comparing the effect on cardiovascular events (case-control study). |
| Kshirsagar 2006103 | Incorrect population. Population had a blood pressure below the diagnsotic threshold for hypertension |
| Obara 2007139 | Incorrect comparison. Comparing predictive value of systolic and diastolic blood pressure for cardiovascular outcomes. |
| Okayama 2006143 | Study took place prior to 2000 date cut off. Incorrect comparison; comparing predictive value of systolic and diastolic blood pressure for cardiovascular outcomes |
| Sairenchi 2005153 | Incorrect study design. Prognostic study comparing predictive value of systolic blood pressure and diastolic blood pressure for the onset of mortality |
| Weitzman 2005186 | Incorrect comparison, incorrect population. Comparing people with normotensive blood pressure to people with hypertension |
From: Evidence review for initiating treatment
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