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whole_rhythm" itemprop="text"><div class="iconblock whole_rhythm clearfix ten_col table-wrap" id="figappglycosylationT"><a href="/books/NBK453071/table/app_glycosylation.T./?report=objectonly" target="object" title="Table 1" class="img_link icnblk_img figpopup" rid-figpopup="figappglycosylationT" rid-ob="figobappglycosylationT"><img class="small-thumb" src="/books/NBK453071/table/app_glycosylation.T./?report=thumb" src-large="/books/NBK453071/table/app_glycosylation.T./?report=previmg" alt="Table 1" /></a><div class="icnblk_cntnt"><h4 id="app_glycosylation.T."><a href="/books/NBK453071/table/app_glycosylation.T./?report=objectonly" target="object" rid-ob="figobappglycosylationT">Table 1</a></h4></div></div><div id="app_glycosylation.Reference_List"><h2 id="_app_glycosylation_Reference_List_">Reference List</h2><ul class="simple-list"><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.akama.2006.8983">Akama TO, Nakagawa H, Wong NK, Sutton-Smith M, Dell A, Morris HR, Nakayama J, Nishimura S, Pai A, Moremen KW, et al. Essential and mutually compensatory roles of α-mannosidase II and α-mannosidase IIx in N-glycan processing in vivo in mice. <span><span class="ref-journal">Proc Natl Acad Sci. </span>2006;<span class="ref-vol">103</span>:8983–8988.</span> [<a href="/pmc/articles/PMC1474017/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1474017</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/16754854" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16754854</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.bian.2011.4051">Bian S, Akyuz N, Bernreuther C, Loers G, Laczynska E, Jakovcevski I, Schachner M. Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells. <span><span class="ref-journal">J Cell Sci. </span>2011;<span class="ref-vol">124</span>:4051–4063.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/22159417" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 22159417</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.biellmann.2008.109">Biellmann F, Hulsmeier AJ, Zhou D, Cinelli P, Hennet T. The Lc3-synthase gene <em>B3gnt5</em> is essential to pre-implantation development of the murine embryo. <span><span class="ref-journal">BMC Dev Biol. </span>2008;<span class="ref-vol">8</span>:109.</span> [<a href="/pmc/articles/PMC2596124/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2596124</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/19014510" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19014510</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.conway.2011.734">Conway CD, Price DJ, Pratt T, Mason JO. Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice. <span><span class="ref-journal">J Anat. </span>2011;<span class="ref-vol">219</span>:734–742.</span> [<a href="/pmc/articles/PMC3237881/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3237881</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/21951307" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21951307</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.derossi.2006.5916">DeRossi C, Bode L, Eklund EA, Zhang F, Davis JA, Westphal V, Wang L, Borowsky AD, Freeze HH. Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality. <span><span class="ref-journal">J Biol Chem. </span>2006;<span class="ref-vol">281</span>:5916–5927.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/16339137" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16339137</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.du.2010.25">Du J, Takeuchi H, Leonhard-Melief C, Shroyer KR, Dlugosz M, Haltiwanger RS, Holdener BC. O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation. <span><span class="ref-journal">Dev Biol. </span>2010;<span class="ref-vol">346</span>:25–38.</span> [<a href="/pmc/articles/PMC2937101/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2937101</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/20637190" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20637190</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.evrard.1998.377">Evrard YA, Lun Y, Aulehla A, Gan L, Johnson RL. <em>lunatic fringe</em> is an essential mediator of somite segmentation and patterning. <span><span class="ref-journal">Nature. </span>1998;<span class="ref-vol">394</span>:377–381.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/9690473" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 9690473</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.fernandezvaldivia.2011.1925">Fernandez-Valdivia R, Takeuchi H, Samarghandi A, Lopez M, Leonardi J, Haltiwanger RS, Jafar-Nejad H. Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi. <span><span class="ref-journal">Development. </span>2011;<span class="ref-vol">138</span>:1925–1934.</span> [<a href="/pmc/articles/PMC3082299/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3082299</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/21490058" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21490058</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.garciagarcia.2003.727">Garcia-Garcia MJ, Anderson KV. Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation. <span><span class="ref-journal">Cell. </span>2003;<span class="ref-vol">114</span>:727–737.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/14505572" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14505572</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.habuchi.2007.15578">Habuchi H, Nagai N, Sugaya N, Atsumi F, Stevens RL, Kimata K. Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality. <span><span class="ref-journal">J Biol Chem. </span>2007;<span class="ref-vol">282</span>:15578–15588.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/17405882" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17405882</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.hellbusch.2007.10762">Hellbusch CC, Sperandio M, Frommhold D, Yakubenia S, Wild MK, Popovici D, Vestweber D, Grone HJ, von Figura K, Lubke T, et al. Golgi GDP-fucose transporter-deficient mice mimic congenital disorder of glycosylation IIc/leukocyte adhesion deficiency II. <span><span class="ref-journal">J Biol Chem. </span>2007;<span class="ref-vol">282</span>:10762–10772.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/17276979" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17276979</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.hiraoka.2007.1363">Hiraoka S, Furuichi T, Nishimura G, Shibata S, Yanagishita M, Rimoin DL, Superti-Furga A, Nikkels PG, Ogawa M, Katsuyama K, et al. Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human. <span><span class="ref-journal">Nat Med. </span>2007;<span class="ref-vol">13</span>:1363–1367.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/17952091" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 17952091</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.holmborn.2004.42355">Holmborn K, Ledin J, Smeds E, Eriksson I, Kusche-Gullberg M, Kjellen L. Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups. <span><span class="ref-journal">J Biol Chem. </span>2004;<span class="ref-vol">279</span>:42355–42358.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/15319440" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15319440</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.hu.2011.1320">Hu H, Li J, Gagen CS, Gray NW, Zhang Z, Qi Y, Zhang P. Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. <span><span class="ref-journal">J Comp Neurol. </span>2011;<span class="ref-vol">519</span>:1320–1337.</span> [<a href="/pmc/articles/PMC3634366/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3634366</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/21452199" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 21452199</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.ioffe.1994.728">Ioffe E, Stanley P. Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. <span><span class="ref-journal">Proc Natl Acad Sci. </span>1994;<span class="ref-vol">91</span>:728–732.</span> [<a href="/pmc/articles/PMC43022/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC43022</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/8290590" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8290590</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.kanagawa.2016.2209">Kanagawa M, Kobayashi K, Tajiri M, Manya H, Kuga A, Yamaguchi Y, Akasaka-Manya K, Furukawa J, Mizuno M, Kawakami H, Shinohara Y, Wada Y, Endo T, Toda T. Identification of a post-translational modification with ribitol-phosphate and its defect in muscular dystrophy. <span><span class="ref-journal">Cell Reports. </span>2016;<span class="ref-vol">14</span>:2209–2223.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/26923585" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 26923585</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.kumagai.2009.456">Kumagai T, Tanaka M, Yokoyama M, Sato T, Shinkai T, Furukawa K. Early lethality of β-1,4-galactosyltransferase V-mutant mice by growth retardation. <span><span class="ref-journal">Biochem Biophys Res Commun. </span>2009;<span class="ref-vol">379</span>:456–459.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/19114028" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 19114028</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.lin.2000.299">Lin X, Wei G, Shi Z, Dryer L, Esko JD, Wells DE, Matzuk MM. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. <span><span class="ref-journal">Dev Biol. </span>2000;<span class="ref-vol">224</span>:299–311.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/10926768" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10926768</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.marek.1999.1263">Marek KW, Vijay IK, Marth JD. A recessive deletion in the GlcNAc-1-phosphotransferase gene results in peri-implantation embryonic lethality. <span><span class="ref-journal">Glycobiology. </span>1999;<span class="ref-vol">9</span>:1263–1271.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/10536042" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10536042</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.metzler.1994.2056">Metzler M, Gertz A, Sarkar M, Schachter H, Schrader JW, Marth JD. Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. <span><span class="ref-journal">EMBO J. </span>1994;<span class="ref-vol">13</span>:2056–2065.</span> [<a href="/pmc/articles/PMC395055/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC395055</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/8187759" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 8187759</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.nishie.2010.1311">Nishie T, Hikimochi Y, Zama K, Fukusumi Y, Ito M, Yokoyama H, Naruse C, Ito M, Asano M. β4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development. <span><span class="ref-journal">Glycobiology. </span>2010;<span class="ref-vol">20</span>:1311–1322.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/20574042" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20574042</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.nozaki.1999.293">Nozaki M, Ohishi K, Yamada N, Kinoshita T, Nagy A, Takeda J. Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system. <span><span class="ref-journal">Lab Invest. </span>1999;<span class="ref-vol">79</span>:293–299.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/10092065" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10092065</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.schwarzkopf.2002.5267">Schwarzkopf M, Knobeloch KP, Rohde E, Hinderlich S, Wiechens N, Lucka L, Horak I, Reutter W, Horstkorte R. Sialylation is essential for early development in mice. <span><span class="ref-journal">Proc Natl Acad Sci. </span>2002;<span class="ref-vol">99</span>:5267–5270.</span> [<a href="/pmc/articles/PMC122758/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC122758</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/11929971" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 11929971</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.shi.2003.5234">Shi S, Stanley P. Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. <span><span class="ref-journal">Proc Natl Acad Sci. </span>2003;<span class="ref-vol">100</span>:5234–5239.</span> [<a href="/pmc/articles/PMC154328/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC154328</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/12697902" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 12697902</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.stickens.2005.5055">Stickens D, Zak BM, Rougier N, Esko JD, Werb Z. Mice deficient in Ext2 lack heparan sulfate and develop exostoses. <span><span class="ref-journal">Development. </span>2005;<span class="ref-vol">132</span>:5055–5068.</span> [<a href="/pmc/articles/PMC2767329/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2767329</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/16236767" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16236767</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.thiel.2006.5615">Thiel C, Lubke T, Matthijs G, von Figura K, Korner C. Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality. <span><span class="ref-journal">Mol Cell Biol. </span>2006;<span class="ref-vol">26</span>:5615–5620.</span> [<a href="/pmc/articles/PMC1592760/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC1592760</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/16847317" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 16847317</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.wang.2010.9228">Wang Y, Ju T, Ding X, Xia B, Wang W, Xia L, He M, Cummings RD. Cosmc is an essential chaperone for correct protein O-glycosylation. <span><span class="ref-journal">Proc Natl Acad Sci U S A. </span>2010;<span class="ref-vol">107</span>:9228–9233.</span> [<a href="/pmc/articles/PMC2889116/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2889116</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/20439703" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 20439703</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.willer.2004.14126">Willer T, Prados B, Falcon-Perez JM, Renner-Muller I, Przemeck GK, Lommel M, Coloma A, Valero MC, de Angelis MH, Tanner W, et al. Targeted disruption of the Walker–Warburg syndrome gene <em>Pomt1</em> in mouse results in embryonic lethality. <span><span class="ref-journal">Proc Natl Acad Sci. </span>2004;<span class="ref-vol">101</span>:14126–14131.</span> [<a href="/pmc/articles/PMC521095/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC521095</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/15383666" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 15383666</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.willer.2014">Willer T, Inamori KI, Venzke D, Harvey C, Morgensen G, Hara Y, Beltran Valero de Bernabe D, Yu L, Wright KM, Campbell KP. The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. <span><span class="ref-journal">eLife. </span>2014;<span class="ref-vol">3</span></span>
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[<a href="/pmc/articles/PMC4227050/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC4227050</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/25279699" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 25279699</span></a>] [<a href="http://dx.crossref.org/10.7554/eLife.03941" ref="pagearea=cite-ref&targetsite=external&targetcat=link&targettype=uri">CrossRef</a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.wright.2012.931">Wright KM, Lyon KA, Leung H, Leahy DJ, Ma L, Ginty DD. Dystroglycan organizes axon guidance cue localization and axonal pathfinding. <span><span class="ref-journal">Neuron. </span>2012;<span class="ref-vol">76</span>:931–944.</span> [<a href="/pmc/articles/PMC3526105/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC3526105</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/23217742" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 23217742</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.xia.2004.451">Xia L, Ju T, Westmuckett A, An G, Ivanciu L, McDaniel JM, Lupu F, Cummings RD, McEver RP. Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans. <span><span class="ref-journal">J Cell Biol. </span>2004;<span class="ref-vol">164</span>:451–459.</span> [<a href="/pmc/articles/PMC2172228/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC2172228</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/14745002" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 14745002</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.yamashita.1999.9142">Yamashita T, Wada R, Sasaki T, Deng C, Bierfreund U, Sandhoff K, Proia RL. A vital role for glycosphingolipid synthesis during development and differentiation. <span><span class="ref-journal">Proc Natl Acad Sci. </span>1999;<span class="ref-vol">96</span>:9142–9147.</span> [<a href="/pmc/articles/PMC17746/" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pmc">PMC free article<span class="bk_prnt">: PMC17746</span></a>] [<a href="https://pubmed.ncbi.nlm.nih.gov/10430909" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 10430909</span></a>]</div></p></li><li class="half_rhythm"><p><div class="bk_ref" id="app_glycosylation.REF.zhang.1998.374">Zhang N, Gridley T. Defects in somite formation in <em>lunatic fringe</em>-deficient mice. <span><span class="ref-journal">Nature. </span>1998;<span class="ref-vol">394</span>:374–377.</span> [<a href="https://pubmed.ncbi.nlm.nih.gov/9690472" ref="pagearea=cite-ref&targetsite=entrez&targetcat=link&targettype=pubmed">PubMed<span class="bk_prnt">: 9690472</span></a>]</div></p></li></ul></div><div id="bk_toc_contnr"></div></div></div><div class="fm-sec"><h2 id="_NBK453071_pubdet_">Publication Details</h2><h3>Author Information and Affiliations</h3><p class="contrib-group"><h4>Authors</h4><span itemprop="author">Michael Pierce</span> and <span itemprop="author">Pamela Stanley</span>.</p><h3>Publication History</h3><p class="small">Published online: <span itemprop="datePublished">September 5, 2017</span>.</p><h3>Copyright</h3><div><div class="half_rhythm"><a href="/books/about/copyright/">Copyright</a> 2015-2017 by The Consortium of Glycobiology Editors, La Jolla, California. All rights reserved.<p class="small">PDF files are not available for download.</p></div></div><h3>Publisher</h3><p><a href="http://www.cshlpress.com/default.tpl?action=full&cart=12210755385880789&--eqskudatarq=666" ref="pagearea=page-banner&targetsite=external&targetcat=link&targettype=publisher">Cold Spring Harbor Laboratory Press</a>, Cold Spring Harbor (NY)</p><h3>NLM Citation</h3><p>Pierce M, Stanley P. Glycosylation Genes Essential for Mouse Embryonic Development. 2017 Sep 5. In: Varki A, Cummings RD, Esko JD, et al., editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Online Appendix 27A.<span class="bk_cite_avail"></span></p></div><div class="small-screen-prev"><a href="/books/n/glyco3/app_gpi_anchor_struct/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M75,30 c-80,60 -80,0 0,60 c-30,-60 -30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Prev</text></svg></a></div><div class="small-screen-next"><a href="/books/n/glyco3/app_gbp/?report=reader"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 100 100" preserveAspectRatio="none"><path d="M25,30c80,60 80,0 0,60 c30,-60 30,0 0,-60"></path><text x="20" y="28" textLength="60" style="font-size:25px">Next</text></svg></a></div></article><article data-type="table-wrap" id="figobappglycosylationT"><div id="app_glycosylation.T." class="table"><h3><span class="label">Table 1</span></h3><p class="large-table-link" style="display:none"><span class="right"><a href="/books/NBK453071/table/app_glycosylation.T./?report=objectonly" target="object">View in own window</a></span></p><div class="large_tbl" id="__app_glycosylation.T._lrgtbl__"><table class="no_bottom_margin"><thead><tr><th id="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gene</th><th id="hd_h_app_glycosylation.T._1_1_1_2" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Glycan substrate accumulated</th><th id="hd_h_app_glycosylation.T._1_1_1_3" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Glycan(s) not generated</th><th id="hd_h_app_glycosylation.T._1_1_1_4" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Stage of death</th><th id="hd_h_app_glycosylation.T._1_1_1_5" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Reference(s)</th></tr></thead><tbody><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>N-glycans</b>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Mpi</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">fructose-6-P</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man-6-P</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E11.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.derossi.2006.5916" rid="app_glycosylation.REF.derossi.2006.5916">DeRossi et al. 2006</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Pmm2</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man-6-P</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man-1-P</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E3.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.thiel.2006.5615" rid="app_glycosylation.REF.thiel.2006.5615">Thiel et al. 2006</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Dpagt1</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Dol-P</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-P-P-Dol</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E4-5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.marek.1999.1263" rid="app_glycosylation.REF.marek.1999.1263">Marek et al. 1999</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Mgat1</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man<sub>5</sub>GlcNAc<sub>2</sub>Asn</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-Man<sub>5</sub>GlcNAc<sub>2</sub>Asn</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><a class="bibr" href="#app_glycosylation.REF.ioffe.1994.728" rid="app_glycosylation.REF.ioffe.1994.728">Ioffe and Stanley 1994</a>; <a class="bibr" href="#app_glycosylation.REF.metzler.1994.2056" rid="app_glycosylation.REF.metzler.1994.2056">Metzler et al. 1994</a></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><i>Man2a1</i>+<br /><i>Man2a2</i></td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAcMan<sub>5</sub>GlcNAc<sub>2</sub>Asn</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-Man<sub>3</sub>GlcNAc<sub>2</sub>Asn</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E15.5-18.5-P0</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.akama.2006.8983" rid="app_glycosylation.REF.akama.2006.8983">Akama et al. 2006</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>GPI-anchors</b>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Piga</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">naked GPI-anchor</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-GPI-anchor</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E7.5-9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.nozaki.1999.293" rid="app_glycosylation.REF.nozaki.1999.293">Nozaki et al. 1999</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>O-GalNAc</b>
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<br />
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<b>glycans</b>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>C1galt1</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GalNAc-O-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gal-GalNAc-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E13.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.xia.2004.451" rid="app_glycosylation.REF.xia.2004.451">Xia et al. 2004</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>C1galt1c1</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GalNAc-O-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gal-GalNAc-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E13.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.wang.2010.9228" rid="app_glycosylation.REF.wang.2010.9228">Wang et al. 2010</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>O-fucose</b>
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<br />
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<b>glycans</b>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Pofut1</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">C<sub>2</sub>XXXXS/TC<sub>3</sub> EGF repeats</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fuc-O-EGF</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.shi.2003.5234" rid="app_glycosylation.REF.shi.2003.5234">Shi and Stanley 2003</a>
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<i>Lfng</i>
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</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fuc-O-EGF</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-Fuc-O-EGF</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">≤P0</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><a class="bibr" href="#app_glycosylation.REF.evrard.1998.377" rid="app_glycosylation.REF.evrard.1998.377">Evrard et al. 1998</a>; <a class="bibr" href="#app_glycosylation.REF.zhang.1998.374" rid="app_glycosylation.REF.zhang.1998.374">Zhang and Gridley 1998</a></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Pofut2</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">TSR type 1 repeats</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Fuc-O-TSR type 1</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E6.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<a class="bibr" href="#app_glycosylation.REF.du.2010.25" rid="app_glycosylation.REF.du.2010.25">Du et al. 2010</a>
|
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</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
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<b>O-mannose</b>
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<br />
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<b>glycans</b>
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|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
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<i>Pomt1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">unmodified Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man-O-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E7.5-9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.willer.2004.14126" rid="app_glycosylation.REF.willer.2004.14126">Willer et al. 2004</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Pomt2</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">unmodified Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Man-O-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.hu.2011.1320" rid="app_glycosylation.REF.hu.2011.1320">Hu et al. 2011</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>B4gat1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Xyl-Rbo5P-Rbo5P-GalNAc-GlcNAc-Man(P)-O-Ser/Thr</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">priming GlcA for XlyGlcA matriglycan added by LARGE</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><a class="bibr" href="#app_glycosylation.REF.wright.2012.931" rid="app_glycosylation.REF.wright.2012.931">Wright et al. 2012</a>; <a class="bibr" href="#app_glycosylation.REF.willer.2014" rid="app_glycosylation.REF.willer.2014">Willer et al. 2014</a>; <a class="bibr" href="#app_glycosylation.REF.kanagawa.2016.2209" rid="app_glycosylation.REF.kanagawa.2016.2209">Kanagawa et al. 2016</a></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>O-glucose</b>
|
|
<br />
|
|
<b>glycans</b>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Poglut1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">C<sub>1</sub>XSXPTC<sub>2</sub> EGF repeats</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Glc-O-EGF repeat</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E10.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.fernandezvaldivia.2011.1925" rid="app_glycosylation.REF.fernandezvaldivia.2011.1925">Fernandez-Valdivia et al. 2011</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Glycosamino-glycans (GAGs)</b>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Ext1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">core GAG lacks HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E6.5-8.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.lin.2000.299" rid="app_glycosylation.REF.lin.2000.299">Lin et al. 2000</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Ext2</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">core GAG lacks HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">E6.5-8.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.stickens.2005.5055" rid="app_glycosylation.REF.stickens.2005.5055">Stickens et al. 2005</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Ndst1+Ndst2</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">no N sulfation of HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HS with GlcNS</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E12.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.holmborn.2004.42355" rid="app_glycosylation.REF.holmborn.2004.42355">Holmborn et al. 2004</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Hs6st1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">reduced 6-O-sulfation GlcN in HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HS with GlcN6S</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">≥E15.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.habuchi.2007.15578" rid="app_glycosylation.REF.habuchi.2007.15578">Habuchi et al. 2007</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Hs6st1+Hs2st</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">very reduced 2-O- and 6-O-sulfation GlcN in HS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">HS with GlcN-O-2S and GlcN-O-6S</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><E15,5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.conway.2011.734" rid="app_glycosylation.REF.conway.2011.734">Conway et al. 2011</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Chst11</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">reduced 4-O-sulfation of GalN in CS</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CS with GalN-O-4S</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~P0</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.bian.2011.4051" rid="app_glycosylation.REF.bian.2011.4051">Bian et al. 2011</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Glycolipids</b>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Ugcg</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Ceramide lacks Glc</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Glc-Cer</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">≤E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.yamashita.1999.9142" rid="app_glycosylation.REF.yamashita.1999.9142">Yamashita et al. 1999</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>B3gnt5</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GalGlc-Cer</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAc-Gal-Glc-Cer</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E3.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.biellmann.2008.109" rid="app_glycosylation.REF.biellmann.2008.109">Biellmann et al. 2008</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>B4galt5</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GlcNAcGalGlc-Cer</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Gal-GlcNAc-Gal-Glc-Cer</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E10.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"><a class="bibr" href="#app_glycosylation.REF.kumagai.2009.456" rid="app_glycosylation.REF.kumagai.2009.456">Kumagai et al. 2009</a>; <a class="bibr" href="#app_glycosylation.REF.nishie.2010.1311" rid="app_glycosylation.REF.nishie.2010.1311">Nishie et al. 2010</a></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="col" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<b>Nucleotide sugars</b>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;"></td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Gne</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">Mannosamine</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GCs without sialic acid</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E9.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.schwarzkopf.2002.5267" rid="app_glycosylation.REF.schwarzkopf.2002.5267">Schwarzkopf et al. 2002</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Ugdh</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">UDP-Glc</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">UDP-GlcA</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~E4.5</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.garciagarcia.2003.727" rid="app_glycosylation.REF.garciagarcia.2003.727">Garcia-Garcia and Anderson 2003</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Slc35c1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GDP-Fuc</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">GCs with little Fuc</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~P0</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.hellbusch.2007.10762" rid="app_glycosylation.REF.hellbusch.2007.10762">Hellbusch et al. 2007</a>
|
|
</td></tr><tr><td headers="hd_h_app_glycosylation.T._1_1_1_1" scope="row" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<i>Slc35d1</i>
|
|
</td><td headers="hd_h_app_glycosylation.T._1_1_1_2" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">high UDP-GlcA and UDP-GalNAc in cytoplasm</td><td headers="hd_h_app_glycosylation.T._1_1_1_3" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">CS GAGs</td><td headers="hd_h_app_glycosylation.T._1_1_1_4" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">~P0</td><td headers="hd_h_app_glycosylation.T._1_1_1_5" rowspan="1" colspan="1" style="text-align:left;vertical-align:top;">
|
|
<a class="bibr" href="#app_glycosylation.REF.hiraoka.2007.1363" rid="app_glycosylation.REF.hiraoka.2007.1363">Hiraoka et al. 2007</a>
|
|
</td></tr></tbody></table></div><div class="tblwrap-foot"><div><dl class="temp-labeled-list small"><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">Modified, with permission, from Stanley P. 2016. What have we learned from glycosyltransferase knockouts in mice? <i>J Mol Biol</i> 2016 Aug 14;428(16):3166-82. doi: 10.1016/j.jmb.2016.03.025.</p></div></dd></dl><dl class="bkr_refwrap"><dt></dt><dd><div><p class="no_margin">TSR, thrombospondin repeat; EGF, epidermal growth factor; LARGE, like-acetylglucosaminyltransferase; GC, glycoconjugate; HS, heparan sulfate; CS, chondroitin sulfate; KS, keratan sulfate.</p></div></dd></dl></dl></div></div></div></article></div><div id="jr-scripts"><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/libs.min.js"> </script><script src="/corehtml/pmc/jatsreader/ptpmc_3.22/js/jr.min.js"> </script></div></div>
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