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<meta name="keywords" content="C1860130, decreased circulating alkaline phosphatase activity, decreased serum alkaline phosphatase, finding, low alkaline phosphatase, low alp, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Concentration or activity of alkaline phosphatase outside the upper or lower limtis of normal in the blood circulation." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=349734
|
||
ConceptID=C1860130
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Decreased circulating alkaline phosphatase activity</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>349734</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1860130</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Decreased serum alkaline phosphatase; Low alkaline phosphatase</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0003282">HP:0003282</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Concentration or activity of alkaline phosphatase outside the upper or lower limtis of normal in the blood circulation. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Decreased circulating alkaline phosphatase activity</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1841674" ref="tree=MeSH" title="MedGen record for Abnormal enzyme concentration or activity">Abnormal enzyme concentration or activity</a></span><ul><li><span class="TLline"><a href="/medgen/1841554" ref="tree=MeSH" title="MedGen record for Abnormal circulating enzyme concentration or activity">Abnormal circulating enzyme concentration or activity</a></span><ul><li><span class="TLline"><a href="/medgen/892397" ref="tree=MeSH" title="MedGen record for Abnormality of alkaline phosphatase level">Abnormality of alkaline phosphatase level</a></span><ul><li><span class="matched_ds">Decreased circulating alkaline phosphatase activity</span><ul><li><span class="TLline"><a href="/medgen/869315" ref="tree=MeSH" title="MedGen record for Low alkaline phosphatase of bone origin">Low alkaline phosphatase of bone origin</a></span></li><li><span class="TLline"><a href="/medgen/869313" ref="tree=MeSH" title="MedGen record for Low alkaline phosphatase of hepatic origin">Low alkaline phosphatase of hepatic origin</a></span></li><li><span class="TLline"><a href="/medgen/869312" ref="tree=MeSH" title="MedGen record for Low intestinal alkaline phosphatase">Low intestinal alkaline phosphatase</a></span></li><li><span class="TLline"><a href="/medgen/1685638" ref="tree=MeSH" title="MedGen record for Low neutrophil alkaline phosphatase">Low neutrophil alkaline phosphatase</a></span></li><li><span class="TLline"><a href="/medgen/869311" ref="tree=MeSH" title="MedGen record for Low placental alkaline phosphatase">Low placental alkaline phosphatase</a></span></li><li><span class="TLline"><a href="/medgen/869316" ref="tree=MeSH" title="MedGen record for Low tissue non-specific alkaline phosphatase">Low tissue non-specific alkaline phosphatase</a></span></li><li><span class="TLline"><a href="/medgen/338120" ref="tree=MeSH" title="MedGen record for Reduced leukocyte alkaline phosphatase">Reduced leukocyte alkaline phosphatase</a></span><ul><li><span class="TLline"><a href="/medgen/870282" ref="tree=MeSH" title="MedGen record for Absent leukocyte alkaline phosphatase">Absent leukocyte alkaline phosphatase</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/16979395">Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Martini G,
|
||
Gennari L,
|
||
Merlotti D,
|
||
Salvadori S,
|
||
Franci MB,
|
||
Campagna S,
|
||
Avanzati A,
|
||
De Paola V,
|
||
Valleggi F,
|
||
Nuti R</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2007 Feb;40(2):457-63.
|
||
Epub 2006 Sep 18
|
||
doi: 10.1016/j.bone.2006.08.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16979395" target="_blank">16979395</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14623063">Circulating osteoprotegerin in women during GnRH-agonist treatment and their relationships with mineral components and biomarkers of bone turnover.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Uemura H,
|
||
Yasui T,
|
||
Umino Y,
|
||
Niki H,
|
||
Takikawa M,
|
||
Saito S,
|
||
Furumoto H,
|
||
Irahara M</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2003 Nov;33(5):860-6.
|
||
doi: 10.1016/j.bone.2003.08.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14623063" target="_blank">14623063</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3257542">The acute effect of high dose corticosteroid treatment on serum osteocalcin.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ekenstam E,
|
||
Stålenheim G,
|
||
Hällgren R</span><br />
|
||
<span class="medgenPMjournal">Metabolism</span>
|
||
1988 Feb;37(2):141-4.
|
||
doi: 10.1016/s0026-0495(98)90008-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3257542" target="_blank">3257542</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(decreased%20circulating%20alkaline%20phosphatase%20activity)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37730530">The effect of intradialytic exercise on calcium, phosphorus and parathyroid hormone: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tabibi MA,
|
||
Wilund KR,
|
||
Salimian N,
|
||
Nikbakht S,
|
||
Soleymany M,
|
||
Roshanaeian Z,
|
||
Nazemi F,
|
||
Ahmadi S</span><br />
|
||
<span class="medgenPMjournal">BMC Nephrol</span>
|
||
2023 Sep 20;24(1):276.
|
||
doi: 10.1186/s12882-023-03327-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37730530" target="_blank">37730530</a><a href="/pmc/articles/PMC10512624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33398414">The Non-invasive Diagnosis of Bone Disorders in CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bover J,
|
||
Ureña-Torres P,
|
||
Cozzolino M,
|
||
Rodríguez-García M,
|
||
Gómez-Alonso C</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2021 Apr;108(4):512-527.
|
||
Epub 2021 Jan 4
|
||
doi: 10.1007/s00223-020-00781-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33398414" target="_blank">33398414</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32701874">Supplementary Energy Increases Bone Formation during Arduous Military Training.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Leary TJ,
|
||
Walsh NP,
|
||
Casey A,
|
||
Izard RM,
|
||
Tang JCY,
|
||
Fraser WD,
|
||
Greeves JP</span><br />
|
||
<span class="medgenPMjournal">Med Sci Sports Exerc</span>
|
||
2021 Feb 1;53(2):394-403.
|
||
doi: 10.1249/MSS.0000000000002473.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32701874" target="_blank">32701874</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30576866">Five-year efficacy and safety of asfotase alfa therapy for adults and adolescents with hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kishnani PS,
|
||
Rockman-Greenberg C,
|
||
Rauch F,
|
||
Bhatti MT,
|
||
Moseley S,
|
||
Denker AE,
|
||
Watsky E,
|
||
Whyte MP</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2019 Apr;121:149-162.
|
||
Epub 2018 Dec 18
|
||
doi: 10.1016/j.bone.2018.12.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30576866" target="_blank">30576866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3881285">Metabolic effects of alcohol.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mezey E</span><br />
|
||
<span class="medgenPMjournal">Fed Proc</span>
|
||
1985 Jan;44(1 Pt 1):134-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3881285" target="_blank">3881285</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20circulating%20alkaline%20phosphatase%20activity%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (54)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34719310">Systems biomarker characteristics of circulating alkaline phosphatase activities for 48 types of human diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Su W,
|
||
Qiu T,
|
||
Zhang M,
|
||
Hao C,
|
||
Zeng P,
|
||
Huang Z,
|
||
Du W,
|
||
Yun T,
|
||
Xuan Y,
|
||
Zhang L,
|
||
Guo Y,
|
||
Jiao W</span><br />
|
||
<span class="medgenPMjournal">Curr Med Res Opin</span>
|
||
2022 Feb;38(2):201-209.
|
||
Epub 2021 Nov 12
|
||
doi: 10.1080/03007995.2021.2000715.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34719310" target="_blank">34719310</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33398414">The Non-invasive Diagnosis of Bone Disorders in CKD.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bover J,
|
||
Ureña-Torres P,
|
||
Cozzolino M,
|
||
Rodríguez-García M,
|
||
Gómez-Alonso C</span><br />
|
||
<span class="medgenPMjournal">Calcif Tissue Int</span>
|
||
2021 Apr;108(4):512-527.
|
||
Epub 2021 Jan 4
|
||
doi: 10.1007/s00223-020-00781-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33398414" target="_blank">33398414</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30638123">Circulating Biomarkers Predicting Longitudinal Changes in Left Ventricular Structure and Function in a General Population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cauwenberghs N,
|
||
Ravassa S,
|
||
Thijs L,
|
||
Haddad F,
|
||
Yang WY,
|
||
Wei FF,
|
||
López B,
|
||
González A,
|
||
Díez J,
|
||
Staessen JA,
|
||
Kuznetsova T</span><br />
|
||
<span class="medgenPMjournal">J Am Heart Assoc</span>
|
||
2019 Jan 22;8(2):e010430.
|
||
doi: 10.1161/JAHA.118.010430.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30638123" target="_blank">30638123</a><a href="/pmc/articles/PMC6497333" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10898339">Markers of bone turnover in bone metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fontana A,
|
||
Delmas PD</span><br />
|
||
<span class="medgenPMjournal">Cancer</span>
|
||
2000 Jun 15;88(12 Suppl):2952-60.
|
||
doi: 10.1002/1097-0142(20000615)88:12+<2952::aid-cncr11>3.0.co;2-m.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10898339" target="_blank">10898339</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/167553">Adult hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sorensen E,
|
||
Flodgaard H</span><br />
|
||
<span class="medgenPMjournal">Acta Med Scand</span>
|
||
1975 May;197(5):357-60.
|
||
doi: 10.1111/j.0954-6820.1975.tb04934.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/167553" target="_blank">167553</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20circulating%20alkaline%20phosphatase%20activity%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32987199">Pharmacodynamics of asfotase alfa in adults with pediatric-onset hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Seefried L,
|
||
Kishnani PS,
|
||
Moseley S,
|
||
Denker AE,
|
||
Watsky E,
|
||
Whyte MP,
|
||
Dahir KM</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2021 Jan;142:115664.
|
||
Epub 2020 Sep 26
|
||
doi: 10.1016/j.bone.2020.115664.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32987199" target="_blank">32987199</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32701874">Supplementary Energy Increases Bone Formation during Arduous Military Training.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Leary TJ,
|
||
Walsh NP,
|
||
Casey A,
|
||
Izard RM,
|
||
Tang JCY,
|
||
Fraser WD,
|
||
Greeves JP</span><br />
|
||
<span class="medgenPMjournal">Med Sci Sports Exerc</span>
|
||
2021 Feb 1;53(2):394-403.
|
||
doi: 10.1249/MSS.0000000000002473.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32701874" target="_blank">32701874</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30576866">Five-year efficacy and safety of asfotase alfa therapy for adults and adolescents with hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kishnani PS,
|
||
Rockman-Greenberg C,
|
||
Rauch F,
|
||
Bhatti MT,
|
||
Moseley S,
|
||
Denker AE,
|
||
Watsky E,
|
||
Whyte MP</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2019 Apr;121:149-162.
|
||
Epub 2018 Dec 18
|
||
doi: 10.1016/j.bone.2018.12.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30576866" target="_blank">30576866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25500268">An alkaline phosphatase transport mechanism in the pathogenesis of Alzheimer's disease and neurodegeneration.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pike AF,
|
||
Kramer NI,
|
||
Blaauboer BJ,
|
||
Seinen W,
|
||
Brands R</span><br />
|
||
<span class="medgenPMjournal">Chem Biol Interact</span>
|
||
2015 Jan 25;226:30-9.
|
||
Epub 2014 Dec 11
|
||
doi: 10.1016/j.cbi.2014.12.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25500268" target="_blank">25500268</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25474287">Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghosh SS,
|
||
Gehr TW,
|
||
Ghosh S</span><br />
|
||
<span class="medgenPMjournal">Molecules</span>
|
||
2014 Dec 2;19(12):20139-56.
|
||
doi: 10.3390/molecules191220139.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25474287" target="_blank">25474287</a><a href="/pmc/articles/PMC6271001" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20circulating%20alkaline%20phosphatase%20activity%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (52)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39020290">Circulating 25-hydroxycholecalciferol and calcium levels, and alkaline phosphatase activity among people living with and without human immunodeficiency virus and injecting drugs in kenya.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Onyango AO,
|
||
Shaviya N,
|
||
Budambula V,
|
||
Orinda GO,
|
||
Anzala O,
|
||
Aabid AA,
|
||
Were T</span><br />
|
||
<span class="medgenPMjournal">BMC Infect Dis</span>
|
||
2024 Jul 17;24(1):703.
|
||
doi: 10.1186/s12879-024-09610-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39020290" target="_blank">39020290</a><a href="/pmc/articles/PMC11256408" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32701874">Supplementary Energy Increases Bone Formation during Arduous Military Training.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">O'Leary TJ,
|
||
Walsh NP,
|
||
Casey A,
|
||
Izard RM,
|
||
Tang JCY,
|
||
Fraser WD,
|
||
Greeves JP</span><br />
|
||
<span class="medgenPMjournal">Med Sci Sports Exerc</span>
|
||
2021 Feb 1;53(2):394-403.
|
||
doi: 10.1249/MSS.0000000000002473.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32701874" target="_blank">32701874</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30638123">Circulating Biomarkers Predicting Longitudinal Changes in Left Ventricular Structure and Function in a General Population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cauwenberghs N,
|
||
Ravassa S,
|
||
Thijs L,
|
||
Haddad F,
|
||
Yang WY,
|
||
Wei FF,
|
||
López B,
|
||
González A,
|
||
Díez J,
|
||
Staessen JA,
|
||
Kuznetsova T</span><br />
|
||
<span class="medgenPMjournal">J Am Heart Assoc</span>
|
||
2019 Jan 22;8(2):e010430.
|
||
doi: 10.1161/JAHA.118.010430.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30638123" target="_blank">30638123</a><a href="/pmc/articles/PMC6497333" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28660376">Bone metabolism markers and angiogenic cytokines as regulators of human hematopoietic stem cell mobilization.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsirkinidis P,
|
||
Terpos E,
|
||
Boutsikas G,
|
||
Papatheodorou A,
|
||
Anargyrou K,
|
||
Lalou E,
|
||
Dimitrakopoulou A,
|
||
Kalpadakis C,
|
||
Konstantopoulos K,
|
||
Siakantaris M,
|
||
Panayiotidis P,
|
||
Pangalis G,
|
||
Kyrtsonis MC,
|
||
Vassilakopoulos T,
|
||
Angelopoulou MK</span><br />
|
||
<span class="medgenPMjournal">J Bone Miner Metab</span>
|
||
2018 Jul;36(4):399-409.
|
||
Epub 2017 Jun 28
|
||
doi: 10.1007/s00774-017-0853-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28660376" target="_blank">28660376</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28006818">Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rao SR,
|
||
Snaith AE,
|
||
Marino D,
|
||
Cheng X,
|
||
Lwin ST,
|
||
Orriss IR,
|
||
Hamdy FC,
|
||
Edwards CM</span><br />
|
||
<span class="medgenPMjournal">Br J Cancer</span>
|
||
2017 Jan 17;116(2):227-236.
|
||
Epub 2016 Dec 22
|
||
doi: 10.1038/bjc.2016.402.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28006818" target="_blank">28006818</a><a href="/pmc/articles/PMC5243990" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20circulating%20alkaline%20phosphatase%20activity%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (16)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39020290">Circulating 25-hydroxycholecalciferol and calcium levels, and alkaline phosphatase activity among people living with and without human immunodeficiency virus and injecting drugs in kenya.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Onyango AO,
|
||
Shaviya N,
|
||
Budambula V,
|
||
Orinda GO,
|
||
Anzala O,
|
||
Aabid AA,
|
||
Were T</span><br />
|
||
<span class="medgenPMjournal">BMC Infect Dis</span>
|
||
2024 Jul 17;24(1):703.
|
||
doi: 10.1186/s12879-024-09610-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39020290" target="_blank">39020290</a><a href="/pmc/articles/PMC11256408" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38159174">The direct impact of pegvisomant on osteoblast functions and bone development.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vitali E,
|
||
Grasso A,
|
||
Schiavone ML,
|
||
Trivellin G,
|
||
Sobacchi C,
|
||
Mione M,
|
||
Mazziotti G,
|
||
Lania A</span><br />
|
||
<span class="medgenPMjournal">J Endocrinol Invest</span>
|
||
2024 Jun;47(6):1385-1394.
|
||
Epub 2023 Dec 30
|
||
doi: 10.1007/s40618-023-02281-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38159174" target="_blank">38159174</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37730530">The effect of intradialytic exercise on calcium, phosphorus and parathyroid hormone: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tabibi MA,
|
||
Wilund KR,
|
||
Salimian N,
|
||
Nikbakht S,
|
||
Soleymany M,
|
||
Roshanaeian Z,
|
||
Nazemi F,
|
||
Ahmadi S</span><br />
|
||
<span class="medgenPMjournal">BMC Nephrol</span>
|
||
2023 Sep 20;24(1):276.
|
||
doi: 10.1186/s12882-023-03327-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37730530" target="_blank">37730530</a><a href="/pmc/articles/PMC10512624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30576866">Five-year efficacy and safety of asfotase alfa therapy for adults and adolescents with hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kishnani PS,
|
||
Rockman-Greenberg C,
|
||
Rauch F,
|
||
Bhatti MT,
|
||
Moseley S,
|
||
Denker AE,
|
||
Watsky E,
|
||
Whyte MP</span><br />
|
||
<span class="medgenPMjournal">Bone</span>
|
||
2019 Apr;121:149-162.
|
||
Epub 2018 Dec 18
|
||
doi: 10.1016/j.bone.2018.12.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30576866" target="_blank">30576866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28628652">MicroRNA-433-3p promotes osteoblast differentiation through targeting DKK1 expression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tang X,
|
||
Lin J,
|
||
Wang G,
|
||
Lu J</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2017;12(6):e0179860.
|
||
Epub 2017 Jun 19
|
||
doi: 10.1371/journal.pone.0179860.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28628652" target="_blank">28628652</a><a href="/pmc/articles/PMC5476290" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20circulating%20alkaline%20phosphatase%20activity%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (57)</a></div></div>
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