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<meta name="keywords" content="C0036095, cancer of salivary gland, gland neoplasm, salivary, gland neoplasms, salivary, neoplasm of saliva-secreting gland, neoplasm of salivary gland, neoplasm of the salivary gland, neoplasm, salivary gland, neoplasms, salivary gland, neoplastic process, saliva-secreting gland neoplasm, saliva-secreting gland neoplasm (disease), saliva-secreting gland tumor, saliva-secreting gland tumour, salivary gland neoplasia, salivary gland neoplasm, salivary gland neoplasms, salivary gland tumor, salivary gland tumour, tumor of saliva-secreting gland, tumor of salivary gland, tumor of the salivary gland, tumour of saliva-secreting gland, tumour of salivary gland, tumour of the salivary gland, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A tumor (abnormal growth of tissue) of a salivary gland." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=20641
|
||
ConceptID=C0036095
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Salivary gland neoplasm</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>20641</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0036095</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Tumor of salivary gland</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Tumor of salivary gland (235132004); Neoplasm of salivary gland (235132004)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100684">HP:0100684</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0021357" target="_blank">MONDO:0021357</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">A tumor (abnormal growth of tissue) of a salivary gland. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0036095[DISCUI]&test_type=Clinical" ref="ncbi_uid=20641">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=20641" ref="ncbi_uid=20641">V</a></span></span><span class="TLline">Salivary gland neoplasm</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/232269" ref="tree=MeSH" title="MedGen record for Head and Neck Disorder">Head and Neck Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/48537" ref="tree=MeSH" title="MedGen record for Disorder of salivary gland">Disorder of salivary gland</a></span><ul><li><span class="matched_ds">Salivary gland neoplasm</span><ul><li><span class="TLline"><a href="/medgen/83857" ref="tree=MeSH" title="MedGen record for Benign neoplasm of salivary gland">Benign neoplasm of salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/96923" ref="tree=MeSH" title="MedGen record for Benign neoplasm of major salivary gland">Benign neoplasm of major salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/99220" ref="tree=MeSH" title="MedGen record for Benign neoplasm of parotid gland">Benign neoplasm of parotid gland</a></span></li><li><span class="TLline"><a href="/medgen/83858" ref="tree=MeSH" title="MedGen record for Benign neoplasm of sublingual gland">Benign neoplasm of sublingual gland</a></span></li><li><span class="TLline"><a href="/medgen/151936" ref="tree=MeSH" title="MedGen record for Benign neoplasm of submandibular gland">Benign neoplasm of submandibular gland</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87508" ref="tree=MeSH" title="MedGen record for Benign neoplasm of minor salivary gland">Benign neoplasm of minor salivary gland</a></span></li><li><span class="TLline"><a href="/medgen/275400" ref="tree=MeSH" title="MedGen record for Pleomorphic adenoma of salivary gland">Pleomorphic adenoma of salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/1750227" ref="tree=MeSH" title="MedGen record for Laryngeal Pleomorphic Adenoma">Laryngeal Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/277361" ref="tree=MeSH" title="MedGen record for Metastasizing Pleomorphic Adenoma of the Salivary Gland">Metastasizing Pleomorphic Adenoma of the Salivary Gland</a></span></li><li><span class="TLline"><a href="/medgen/277447" ref="tree=MeSH" title="MedGen record for Oral Cavity Pleomorphic Adenoma">Oral Cavity Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/1747126" ref="tree=MeSH" title="MedGen record for Oropharyngeal Pleomorphic Adenoma">Oropharyngeal Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/91155" ref="tree=MeSH" title="MedGen record for Parotid Gland Pleomorphic Adenoma">Parotid Gland Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/1767273" ref="tree=MeSH" title="MedGen record for Sinonasal Pleomorphic Adenoma">Sinonasal Pleomorphic Adenoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234767" ref="tree=MeSH" title="MedGen record for Salivary Gland Cystadenoma">Salivary Gland Cystadenoma</a></span></li><li><span class="TLline"><a href="/medgen/234768" ref="tree=MeSH" title="MedGen record for Salivary Gland Ductal Papilloma">Salivary Gland Ductal Papilloma</a></span><ul><li><span class="TLline"><a href="/medgen/277629" ref="tree=MeSH" title="MedGen record for Salivary Gland Intraductal Papilloma">Salivary Gland Intraductal Papilloma</a></span></li><li><span class="TLline"><a href="/medgen/235574" ref="tree=MeSH" title="MedGen record for Salivary Gland Inverted Ductal Papilloma">Salivary Gland Inverted Ductal Papilloma</a></span></li><li><span class="TLline"><a href="/medgen/234770" ref="tree=MeSH" title="MedGen record for Salivary Gland Sialadenoma Papilliferum">Salivary Gland Sialadenoma Papilliferum</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/785105" ref="tree=MeSH" title="MedGen record for Salivary Gland Hemangioma">Salivary Gland Hemangioma</a></span><ul><li><span class="TLline"><a href="/medgen/233312" ref="tree=MeSH" title="MedGen record for Parotid Gland Hemangioma">Parotid Gland Hemangioma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1747288" ref="tree=MeSH" title="MedGen record for Salivary Gland Lipoma">Salivary Gland Lipoma</a></span><ul><li><span class="TLline"><a href="/medgen/277504" ref="tree=MeSH" title="MedGen record for Parotid Gland Lipoma">Parotid Gland Lipoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1726346" ref="tree=MeSH" title="MedGen record for Salivary Gland Lymphadenoma">Salivary Gland Lymphadenoma</a></span><ul><li><span class="TLline"><a href="/medgen/235576" ref="tree=MeSH" title="MedGen record for Salivary Gland Sebaceous Lymphadenoma">Salivary Gland Sebaceous Lymphadenoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/64421" ref="tree=MeSH" title="MedGen record for Salivary Gland Monomorphic Adenoma">Salivary Gland Monomorphic Adenoma</a></span><ul><li><span class="TLline"><a href="/medgen/104696" ref="tree=MeSH" title="MedGen record for Basal Cell Adenoma">Basal Cell Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/233797" ref="tree=MeSH" title="MedGen record for Oral Cavity Monomorphic Adenoma">Oral Cavity Monomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/277505" ref="tree=MeSH" title="MedGen record for Parotid Gland Monomorphic Adenoma">Parotid Gland Monomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/277628" ref="tree=MeSH" title="MedGen record for Salivary Gland Canalicular Adenoma">Salivary Gland Canalicular Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/233431" ref="tree=MeSH" title="MedGen record for Salivary gland oncocytoma">Salivary gland oncocytoma</a></span></li><li><span class="TLline"><a href="/medgen/277631" ref="tree=MeSH" title="MedGen record for Salivary Gland Sebaceous Adenoma">Salivary Gland Sebaceous Adenoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272365" ref="tree=MeSH" title="MedGen record for Salivary Gland Myoepithelioma">Salivary Gland Myoepithelioma</a></span></li><li><span class="TLline"><a href="/medgen/1730527" ref="tree=MeSH" title="MedGen record for Salivary Gland Nodular Fasciitis">Salivary Gland Nodular Fasciitis</a></span><ul><li><span class="TLline"><a href="/medgen/1747925" ref="tree=MeSH" title="MedGen record for Parotid Gland Nodular Fasciitis">Parotid Gland Nodular Fasciitis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/474884" ref="tree=MeSH" title="MedGen record for Sclerosing Polycystic Adenoma">Sclerosing Polycystic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/1777716" ref="tree=MeSH" title="MedGen record for Sialolipoma">Sialolipoma</a></span><ul><li><span class="TLline"><a href="/medgen/1746820" ref="tree=MeSH" title="MedGen record for Parotid Gland Sialolipoma">Parotid Gland Sialolipoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124" ref="tree=MeSH" title="MedGen record for Warthin tumor">Warthin tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1786641" ref="tree=MeSH" title="MedGen record for Lacrimal Gland Warthin Tumor">Lacrimal Gland Warthin Tumor</a></span></li><li><span class="TLline"><a href="/medgen/365325" ref="tree=MeSH" title="MedGen record for Parotid Gland Warthin Tumor">Parotid Gland Warthin Tumor</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1793275" ref="tree=MeSH" title="MedGen record for Hybrid Salivary Gland Tumor">Hybrid Salivary Gland Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1793276" ref="tree=MeSH" title="MedGen record for Hybrid Salivary Gland Carcinoma">Hybrid Salivary Gland Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83383" ref="tree=MeSH" title="MedGen record for Neoplasm of major salivary gland">Neoplasm of major salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/96919" ref="tree=MeSH" title="MedGen record for Major salivary gland cancer">Major salivary gland cancer</a></span><ul><li><span class="TLline"><a href="/medgen/235287" ref="tree=MeSH" title="MedGen record for Major salivary gland carcinoma">Major salivary gland carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233140" ref="tree=MeSH" title="MedGen record for Major Salivary Gland Non-Hodgkin Lymphoma">Major Salivary Gland Non-Hodgkin Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/233141" ref="tree=MeSH" title="MedGen record for Major Salivary Gland Sarcoma">Major Salivary Gland Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235299" ref="tree=MeSH" title="MedGen record for Malignant Mixed Tumor of the Major Salivary Gland">Malignant Mixed Tumor of the Major Salivary Gland</a></span></li><li><span class="TLline"><a href="/medgen/152885" ref="tree=MeSH" title="MedGen record for Parotid gland cancer">Parotid gland cancer</a></span></li><li><span class="TLline"><a href="/medgen/102263" ref="tree=MeSH" title="MedGen record for Sublingual gland cancer">Sublingual gland cancer</a></span></li><li><span class="TLline"><a href="/medgen/57782" ref="tree=MeSH" title="MedGen record for Submandibular gland cancer">Submandibular gland cancer</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/18313" ref="tree=MeSH" title="MedGen record for Parotid gland neoplasm">Parotid gland neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/87507" ref="tree=MeSH" title="MedGen record for Mixed Tumor of the Parotid Gland">Mixed Tumor of the Parotid Gland</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/21371" ref="tree=MeSH" title="MedGen record for Sublingual gland neoplasm">Sublingual gland neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/20986" ref="tree=MeSH" title="MedGen record for Submandibular gland neoplasm">Submandibular gland neoplasm</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/138022" ref="tree=MeSH" title="MedGen record for Neoplasm of minor salivary gland">Neoplasm of minor salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/91049" ref="tree=MeSH" title="MedGen record for Malignant tumor of minor salivary gland">Malignant tumor of minor salivary gland</a></span><ul><li><span class="TLline"><a href="/medgen/277337" ref="tree=MeSH" title="MedGen record for Malignant Mixed Tumor of the Minor Salivary Gland">Malignant Mixed Tumor of the Minor Salivary Gland</a></span></li><li><span class="TLline"><a href="/medgen/233710" ref="tree=MeSH" title="MedGen record for Minor salivary gland carcinoma">Minor salivary gland carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1793127" ref="tree=MeSH" title="MedGen record for Minor Salivary Gland Intraductal Papillary Neoplasm">Minor Salivary Gland Intraductal Papillary Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/1793128" ref="tree=MeSH" title="MedGen record for Minor Salivary Gland Intraductal Papillary-Mucinous Neoplasm">Minor Salivary Gland Intraductal Papillary-Mucinous Neoplasm</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1800806" ref="tree=MeSH" title="MedGen record for Parotid adenoma">Parotid adenoma</a></span></li><li><span class="TLline"><a href="/medgen/44467" ref="tree=MeSH" title="MedGen record for Pleomorphic adenoma">Pleomorphic adenoma</a></span><ul><li><span class="TLline"><a href="/medgen/267412" ref="tree=MeSH" title="MedGen record for Breast Pleomorphic Adenoma">Breast Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/414992" ref="tree=MeSH" title="MedGen record for Cellular Pleomorphic Adenoma">Cellular Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/91100" ref="tree=MeSH" title="MedGen record for Lacrimal Gland Pleomorphic Adenoma">Lacrimal Gland Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/313372" ref="tree=MeSH" title="MedGen record for Lung Pleomorphic Adenoma">Lung Pleomorphic Adenoma</a></span></li><li><span class="TLline"><a href="/medgen/138003" ref="tree=MeSH" title="MedGen record for Malignant Mixed Tumor of the Salivary Gland">Malignant Mixed Tumor of the Salivary Gland</a></span><ul><li><span class="TLline"><a href="/medgen/274190" ref="tree=MeSH" title="MedGen record for Salivary gland carcinoma ex pleomorphic adenoma">Salivary gland carcinoma ex pleomorphic adenoma</a></span></li><li><span class="TLline"><a href="/medgen/272435" ref="tree=MeSH" title="MedGen record for Salivary Gland Carcinosarcoma">Salivary Gland Carcinosarcoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1864370" ref="tree=MeSH" title="MedGen record for Salivary basal cell adenoma">Salivary basal cell adenoma</a></span></li><li><span class="TLline"><a href="/medgen/65079" ref="tree=MeSH" title="MedGen record for Salivary gland cancer">Salivary gland cancer</a></span><ul><li><span class="TLline"><a href="/medgen/237163" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Salivary Gland Neoplasm">Recurrent Malignant Salivary Gland Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/78919" ref="tree=MeSH" title="MedGen record for Recurrent Salivary Gland Carcinoma">Recurrent Salivary Gland Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1786322" ref="tree=MeSH" title="MedGen record for Refractory Malignant Salivary Gland Neoplasm">Refractory Malignant Salivary Gland Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/1785855" ref="tree=MeSH" title="MedGen record for Refractory Salivary Gland Carcinoma">Refractory Salivary Gland Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/215302" ref="tree=MeSH" title="MedGen record for Salivary gland carcinoma">Salivary gland carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/859688" ref="tree=MeSH" title="MedGen record for Adult Salivary Gland Carcinoma">Adult Salivary Gland Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/859236" ref="tree=MeSH" title="MedGen record for Childhood Salivary Gland Carcinoma">Childhood Salivary Gland Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1676948" ref="tree=MeSH" title="MedGen record for Metastatic Salivary Gland Carcinoma">Metastatic Salivary Gland Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79033" ref="tree=MeSH" title="MedGen record for Salivary Gland Adenocarcinoma">Salivary Gland Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79034" ref="tree=MeSH" title="MedGen record for Salivary gland adenoid cystic carcinoma">Salivary gland adenoid cystic carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277627" ref="tree=MeSH" title="MedGen record for Salivary gland adenosquamous carcinoma">Salivary gland adenosquamous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/407965" ref="tree=MeSH" title="MedGen record for Salivary Gland Clear Cell Carcinoma">Salivary Gland Clear Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234769" ref="tree=MeSH" title="MedGen record for Salivary gland epithelial myoepithelial carcinoma">Salivary gland epithelial myoepithelial carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/124649" ref="tree=MeSH" title="MedGen record for Salivary Gland High Grade Carcinoma">Salivary Gland High Grade Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79029" ref="tree=MeSH" title="MedGen record for Salivary Gland Low Grade Carcinoma">Salivary Gland Low Grade Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277304" ref="tree=MeSH" title="MedGen record for Salivary Gland Lymphoepithelial Carcinoma">Salivary Gland Lymphoepithelial Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277630" ref="tree=MeSH" title="MedGen record for Salivary gland mucoepidermoid carcinoma">Salivary gland mucoepidermoid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235575" ref="tree=MeSH" title="MedGen record for Salivary Gland Myoepithelial Carcinoma">Salivary Gland Myoepithelial Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1724431" ref="tree=MeSH" title="MedGen record for Salivary Gland Poorly Differentiated Carcinoma">Salivary Gland Poorly Differentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83545" ref="tree=MeSH" title="MedGen record for Salivary gland squamous cell carcinoma">Salivary gland squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/124651" ref="tree=MeSH" title="MedGen record for Salivary Gland Undifferentiated Carcinoma">Salivary Gland Undifferentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1777899" ref="tree=MeSH" title="MedGen record for Unresectable Salivary Gland Carcinoma">Unresectable Salivary Gland Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1727252" ref="tree=MeSH" title="MedGen record for Salivary Gland Lymphoma">Salivary Gland Lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/1760831" ref="tree=MeSH" title="MedGen record for Salivary Gland Hodgkin Lymphoma">Salivary Gland Hodgkin Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/1740558" ref="tree=MeSH" title="MedGen record for Salivary Gland Non-Hodgkin Lymphoma">Salivary Gland Non-Hodgkin Lymphoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/274193" ref="tree=MeSH" title="MedGen record for Salivary Gland Myoepithelial Tumor">Salivary Gland Myoepithelial Tumor</a></span></li><li><span class="TLline"><a href="/medgen/690115" ref="tree=MeSH" title="MedGen record for Sialoblastoma">Sialoblastoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_275400"><div><strong>Pleomorphic adenoma of salivary gland</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>275400</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1519176</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">A rare tumor of salivary glands characterized by a benign, well-circumscribed, slow-growing, painless mass most commonly occurring in the parotid gland (but also the palate, submandibular gland, or nasal septal mucosa), histopathologically composed of epithelial and myoepithelial / stromal components. Possible signs and symptoms depend on the location of the tumor and include facial nerve weakness, mild dysphagia, or unilateral nasal obstruction. Recurrence rates are low, although tumor rupture and spillage have been reported. Malignant transformation may occur in a small percentage of cases.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/275400">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_275400" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pleomorphic adenoma of salivary gland</a></div></div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/30549361">Contemporary management of primary parapharyngeal space tumors.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">López F,
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Suárez C,
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Vander Poorten V,
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Mäkitie A,
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Nixon IJ,
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Strojan P,
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Hanna EY,
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Rodrigo JP,
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de Bree R,
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Quer M,
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Takes RP,
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Bradford CR,
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Shaha AR,
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Sanabria A,
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Rinaldo A,
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Ferlito A</span><br />
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<span class="medgenPMjournal">Head Neck</span>
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2019 Feb;41(2):522-535.
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Epub 2018 Dec 14
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doi: 10.1002/hed.25439.
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<span class="bold">PMID: </span><a href="/pubmed/30549361" target="_blank">30549361</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29419396">Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Alamri AM,
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Liu X,
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Blancato JK,
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Haddad BR,
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Wang W,
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Zhong X,
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Choudhary S,
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Krawczyk E,
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Kallakury BV,
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Davidson BJ,
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Furth PA</span><br />
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<span class="medgenPMjournal">Dis Model Mech</span>
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2018 Jan 29;11(1)
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doi: 10.1242/dmm.031716.
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<span class="bold">PMID: </span><a href="/pubmed/29419396" target="_blank">29419396</a><a href="/pmc/articles/PMC5818080" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/8734415">Classification and differential diagnosis of clear and basal cell tumors of the salivary glands.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Seifert G</span><br />
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<span class="medgenPMjournal">Semin Diagn Pathol</span>
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1996 May;13(2):95-103.
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<span class="bold">PMID: </span><a href="/pubmed/8734415" target="_blank">8734415</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22salivary%20gland%20neoplasm%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (10)</a></div></div>
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</div>
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<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
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to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
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<div class="portlet mgSection" id="ID_103">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37074867">Updated Salivary Gland Immunohistochemistry: A Review.</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (142)</a></div><h3 class="subhead">Diagnosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37074867">Updated Salivary Gland Immunohistochemistry: A Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Swid MA,
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Li L,
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<span class="bold">PMID: </span><a href="/pubmed/37074867" target="_blank">37074867</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (287)</a></div><h3 class="subhead">Therapy</h3>
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<div class="portlet_content ln"><span class="medgenPMauthor">Vories AA,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37357912">Clinicopathological study and survival outcomes of sialoblastoma: A systematic review.</a></div>
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Pérez-de-Oliveira ME,
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Louredo BVR,
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Lopes MA,
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<span class="bold">PMID: </span><a href="/pubmed/37357912" target="_blank">37357912</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33526222">Sialadenoma Papilliferum.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hsieh MS,
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Bishop JA,
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Yu Fong Chang J</span><br />
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Epub 2021 Jan 5
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<span class="bold">PMID: </span><a href="/pubmed/33526222" target="_blank">33526222</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32493686">A systematic review of secretory carcinoma of the salivary gland: where are we?</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Alves LDB,
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<span class="bold">PMID: </span><a href="/pubmed/30269389" target="_blank">30269389</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25841941">Epithelial-myoepithelial carcinoma--review of clinicopathological and immunohistochemical features.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (96)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/35637572">Application of the Milan System for Reporting Salivary Gland Cytopathology: A systematic review and meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wang Z,
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<div class="nl"><a target="_blank" href="/pubmed/35460214">Salivary gland neoplasms with basaloid features in the era of the Milan system for reporting salivary gland cytology: Classification and interobserver agreement.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Layfield LJ,
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<span class="bold">PMID: </span><a href="/pubmed/35460214" target="_blank">35460214</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30269389">t(6;9)(MYB-NFIB) in head and neck adenoid cystic carcinoma: A systematic review with meta-analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">de Almeida-Pinto YD,
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Costa SFDS,
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de Andrade BAB,
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Altemani A,
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Vargas PA,
|
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Abreu LG,
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Fonseca FP</span><br />
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<span class="medgenPMjournal">Oral Dis</span>
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2019 Jul;25(5):1277-1282.
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Epub 2019 Jan 1
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doi: 10.1111/odi.12984.
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<span class="bold">PMID: </span><a href="/pubmed/30269389" target="_blank">30269389</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28709532">Margins for Benign Salivary Gland Neoplasms of the Head and Neck.</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/28709532" target="_blank">28709532</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25706172">Hyalinizing clear cell carcinoma of the nasopharynx operated by trans-oral and trans-palatal approach.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Nakashima T,
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Yasumatsu R,
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Yamauchi M,
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Nakano T,
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Yamamoto H,
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<span class="bold">PMID: </span><a href="/pubmed/25706172" target="_blank">25706172</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (69)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37357912">Clinicopathological study and survival outcomes of sialoblastoma: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cruz VMS,
|
||
Pérez-de-Oliveira ME,
|
||
Dos Santos Leite ÉG,
|
||
Louredo BVR,
|
||
Bezerra HKF,
|
||
Lopes MA,
|
||
Vargas PA,
|
||
Santos-Silva AR,
|
||
Kowalski LP,
|
||
da Cruz Perez DE</span><br />
|
||
<span class="medgenPMjournal">Head Neck</span>
|
||
2023 Aug;45(8):2136-2148.
|
||
Epub 2023 Jun 26
|
||
doi: 10.1002/hed.27440.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37357912" target="_blank">37357912</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35637572">Application of the Milan System for Reporting Salivary Gland Cytopathology: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Z,
|
||
Zhao H,
|
||
Guo H,
|
||
An C</span><br />
|
||
<span class="medgenPMjournal">Cancer Cytopathol</span>
|
||
2022 Nov;130(11):849-859.
|
||
Epub 2022 May 30
|
||
doi: 10.1002/cncy.22604.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35637572" target="_blank">35637572</a><a href="/pmc/articles/PMC9796751" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32493686">A systematic review of secretory carcinoma of the salivary gland: where are we?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alves LDB,
|
||
de Melo AC,
|
||
Farinha TA,
|
||
de Lima Araujo LH,
|
||
Thiago LS,
|
||
Dias FL,
|
||
Antunes HS,
|
||
Amaral Eisenberg AL,
|
||
Santos Thuler LC,
|
||
Cohen Goldemberg D</span><br />
|
||
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol Oral Radiol</span>
|
||
2021 Oct;132(4):e143-e152.
|
||
Epub 2020 May 31
|
||
doi: 10.1016/j.oooo.2020.04.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32493686" target="_blank">32493686</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32671867">Comparison of core needle biopsy and fine-needle aspiration in diagnosis of ma lignant salivary gland neoplasm: Systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cho J,
|
||
Kim J,
|
||
Lee JS,
|
||
Chee CG,
|
||
Kim Y,
|
||
Choi SI</span><br />
|
||
<span class="medgenPMjournal">Head Neck</span>
|
||
2020 Oct;42(10):3041-3050.
|
||
Epub 2020 Jul 16
|
||
doi: 10.1002/hed.26377.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32671867" target="_blank">32671867</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31029591">Application of diffusion-weighted magnetic resonance imaging in the diagnosis of salivary gland diseases: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Munhoz L,
|
||
Ramos EADA,
|
||
Im DC,
|
||
Hisatomi M,
|
||
Yanagi Y,
|
||
Asaumi J,
|
||
Arita ES</span><br />
|
||
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol Oral Radiol</span>
|
||
2019 Sep;128(3):280-310.
|
||
Epub 2019 Mar 1
|
||
doi: 10.1016/j.oooo.2019.02.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31029591" target="_blank">31029591</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Salivary%20gland%20neoplasm%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0036095%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
|
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<li><a href="/gtr/tests?term=C0036095%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
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