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<span class="search-input-link user-guide-link" role="navigation" aria-label="User guide">
|
||
<a href="/help/"
|
||
data-ga-category="featured_link"
|
||
data-ga-action="user_guide">
|
||
User Guide
|
||
</a>
|
||
</span>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</form>
|
||
|
||
|
||
<div id="article-page-header">
|
||
<div id="article-top-actions-bar" class="article-top-actions-bar">
|
||
<div class="inner-wrap">
|
||
<div class="actions-container">
|
||
<div class="return-to-search">
|
||
|
||
|
||
</div>
|
||
|
||
<div class="multiple-results-actions " role="region" aria-label="save, email, send to">
|
||
<button id="save-results-panel-trigger"
|
||
type="button"
|
||
class="save-results save-results-panel-trigger"
|
||
aria-expanded="false"
|
||
aria-controls="save-action-panel"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="open">
|
||
Save
|
||
</button><button id="email-results-panel-trigger"
|
||
type="button"
|
||
class="email-results email-results-panel-trigger"
|
||
aria-expanded="false"
|
||
aria-controls="email-action-panel"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="open">
|
||
Email
|
||
</button><div class="more-actions dropdown-block"><button id="more-actions-trigger"
|
||
type="button"
|
||
class="trigger more-actions-trigger"
|
||
ref="linksrc=show_moreactions_btn"
|
||
aria-label="Send to"
|
||
aria-controls="more-actions-dropdown">Send to</button><div id="more-actions-dropdown" class="dropdown dropdown-container" hidden><div class="content"><ul class="more-actions-links"><li><a class="clipboard-panel-trigger dropdown-block-link "
|
||
href="#"
|
||
role="button"
|
||
data-ga-category="save_share"
|
||
data-ga-action="clipboard"
|
||
data-ga-label="send">
|
||
Clipboard
|
||
</a></li><li><a role="button" class="dropdown-block-link bibliography-trigger-target" href="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F27043185%2F%23open-bibliography-panel">My Bibliography</a></li><li><a role="button" class="dropdown-block-link collections-trigger-target" href="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F27043185%2F%23open-collections-panel">Collections</a></li><li><a role="button" class="citation-manager-panel-trigger dropdown-block-link citation-manager-trigger-target" href="#">Citation manager</a></li></ul></div></div></div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region">
|
||
<button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog">
|
||
<span class="button-label">Display options</span>
|
||
</button>
|
||
|
||
<div class="dropdown" hidden>
|
||
<div class="title">
|
||
Display options
|
||
</div>
|
||
|
||
<div class="content">
|
||
|
||
<div class="format-container">
|
||
<span class="option-label">
|
||
Format
|
||
</span>
|
||
<select name="format" data-initial-value="abstract" aria-label="Display format" id="article-display-format">
|
||
<option value="abstract">Abstract</option>
|
||
|
||
<option value="pubmed">PubMed</option>
|
||
|
||
<option value="pmid">PMID</option>
|
||
|
||
</select>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="article-panels-container" class="article-panels-container">
|
||
<div id="save-action-panel" class="save-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Save citation to file
|
||
</h2>
|
||
<form id="save-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="save-action-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="save-action-format" name="results-format" class="action-panel-selector">
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="pubmed-text">PubMed</option>
|
||
<option value="pmid">PMID</option>
|
||
<option value="abstract">Abstract (text)</option>
|
||
<option value="csv">CSV</option>
|
||
</select>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Save citations to file' panel"
|
||
ref="linksrc=close_save_panel"
|
||
aria-controls="save-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="email-action-panel"
|
||
class="email-action-panel action-panel"
|
||
aria-hidden="true"
|
||
data-recaptcha-script-url="https://www.recaptcha.net/recaptcha/enterprise.js?render=explicit&onload=onloadCaptchaCallback"
|
||
data-recaptcha-enabled="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Email citation
|
||
</h2>
|
||
<form id="email-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/send-email/"
|
||
data-by-search-action="/results-export-email-by-search-data/"
|
||
data-by-ids-action="/send-email/"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post"
|
||
method="post"
|
||
>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<span class="action-panel-label">
|
||
Subject:
|
||
</span>
|
||
<span class="email-subject" id="email-subject" aria-label="Email subject">1 selected item: 27043185 - PubMed</span>
|
||
<input type="hidden" name="email-subject" value="1 selected item: 27043185"/>
|
||
<input type="hidden" name="email-subject-hash" value="254e1a1d7910acfd76c0a7ab17eaab56777a4192ad4760dd37c33e2d73a3a346"/>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-to" class="action-panel-label required-field-asterisk">
|
||
To:
|
||
</label>
|
||
<input type="email" aria-label="Recipient Email Address" placeholder="email@example.com" id="email-to" class="email-to" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="100" required>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-from" class="action-panel-label">
|
||
From:
|
||
</label>
|
||
<input type="email" aria-label="Sender Email Address" placeholder="email@example.com" id="email-from" class="email-from" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="256">
|
||
</div>
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-citation-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="email-citation-format" name="citation-format" class="action-panel-selector email-citation-format">
|
||
<option selected="selected" value="summary">Summary</option>
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="abstract">Abstract</option>
|
||
<option value="abstract-text">Abstract (text)</option>
|
||
|
||
</select>
|
||
</div>
|
||
<div class="include-supplemental-container">
|
||
<input type="checkbox" aria-label="Include MeSH and other data" name="include-supplemental" id="email-include-supplemental" class="email-include-supplemental">
|
||
<label for="email-include-supplemental" class="email-include-supplemental-label">MeSH and other data</label>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="form-field recaptcha ">
|
||
|
||
|
||
|
||
<div class="g-recaptcha" id="id-recaptcha" data-sitekey="6LfsWHMdAAAAAClKbtOpjQ2pMjgsGxvv7NdZW9uI"></div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div id="captcha-error-message" class="usa-input-error-message captcha-validation-message" role="alert"></div>
|
||
|
||
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="send">
|
||
Send email
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Email citations' panel"
|
||
ref="linksrc=close_email_panel"
|
||
aria-controls="email-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
<input type="hidden" name="email-search-details" value="" />
|
||
<input type="hidden" name="email-search-details-hash" value="0e42663a6c3bd85498fcb88798998fed7bfdc45d457db35281e41afe13cc0524" />
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="collections-action-panel"
|
||
class="collections-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-collections-open-panel-enabled="false"
|
||
data-collections-open-panel-url-hash="#open-collections-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to Collections
|
||
</h3>
|
||
|
||
|
||
<form id="collections-action-panel-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-add-to-collection-max-amount="1000"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
|
||
|
||
<div class="choice-group" role="radiogroup">
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_new">
|
||
<label for="collections-action-panel-new">Create a new collection</label>
|
||
</li>
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_existing">
|
||
<label for="collections-action-panel-existing">Add to an existing collection</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="controls-wrapper">
|
||
<div class="action-panel-control-wrap new-collections-controls">
|
||
<label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label>
|
||
<input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-panel-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="save_share"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection">
|
||
<div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div>
|
||
</div>
|
||
<div class="action-panel-control-wrap existing-collections-controls">
|
||
<label for="collections-action-panel-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label>
|
||
<select id="collections-action-panel-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="save_share"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'">
|
||
</select>
|
||
<div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="add">
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="bibliography-action-panel"
|
||
class="bibliography-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-bibliography-open-panel-enabled="false"
|
||
data-bibliography-open-panel-url-hash="#open-bibliography-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to My Bibliography
|
||
</h3>
|
||
<form id="bibliography-action-panel-form"
|
||
class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-add-to-bibliography-max-amount="100"
|
||
data-add-to-bibliography-batch-size="10"
|
||
data-bibliography-delegates-url="/list-bibliography-delegates/"
|
||
data-add-to-bibliography-url="/add-to-bibliography/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap bibliographies-controls">
|
||
<div class="choice-group">
|
||
<ul class="bibliographies-action-add radio-group-items">
|
||
<li>
|
||
<input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/>
|
||
<label for="my-bibliography">My Bibliography</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your delegates due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore>
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to bibliography' panel"
|
||
ref="linksrc=close_bibliography_panel"
|
||
aria-controls="bibliography-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="mybib"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true"
|
||
data-saved-search-open-panel-enabled="false"
|
||
data-saved-search-open-panel-url-hash="#open-saved-search-panel">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your saved search
|
||
</h2>
|
||
|
||
<form id="saved-search-action-panel-form"
|
||
class="saved-search-action-panel-form action-panel-content action-form"
|
||
data-create-saved-search-url="/create-saved-search/"
|
||
data-try-search-terms-url="/try-search-term/"
|
||
data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk">
|
||
Name of saved search:
|
||
</label>
|
||
<input maxlength="200"
|
||
type="text"
|
||
name="saved-search-name"
|
||
id="saved-search-name"
|
||
class="saved-search-name"
|
||
value=""
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-term" class="action-panel-label required-field-asterisk">
|
||
Search terms:
|
||
</label>
|
||
<textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea>
|
||
</div>
|
||
<div class="test-search-term-wrap">
|
||
<a href="#" class="try-search-term">Test search terms</a>
|
||
</div>
|
||
<div class="choice-group action-panel-extra-margin-top">
|
||
<span class="action-panel-label" id="fieldset-label">
|
||
Would you like email updates of new search results?
|
||
</span>
|
||
<fieldset id="saved-search-alert" aria-describedby="fieldset-label">
|
||
<legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend>
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked>
|
||
<label for="saved-search-alert-yes" class="action-panel-label">Yes</label>
|
||
</li>
|
||
<li>
|
||
<input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no">
|
||
<label for="saved-search-alert-no" class="action-panel-label">No</label>
|
||
</li>
|
||
</ul>
|
||
</fieldset>
|
||
</div>
|
||
|
||
<div class="alert-schedule-wrap">
|
||
<div class="action-panel-control-wrap">
|
||
<label class="action-panel-label">
|
||
Email:
|
||
</label>
|
||
<span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
|
||
</div>
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="saved-search-frequency" class="action-panel-label">
|
||
Frequency:
|
||
</label>
|
||
<select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency">
|
||
<option value="monthly">Monthly</option>
|
||
<option value="weekly">Weekly</option>
|
||
<option value="daily">Daily</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-monthly-additional">
|
||
<label for="saved-search-monthly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-monthly-on-day" class="no-border-panel-selector">
|
||
<option value="Sunday">The first Sunday</option>
|
||
<option value="Monday">The first Monday</option>
|
||
<option value="Tuesday">The first Tuesday</option>
|
||
<option value="Wednesday">The first Wednesday</option>
|
||
<option value="Thursday">The first Thursday</option>
|
||
<option value="Friday">The first Friday</option>
|
||
<option value="Saturday">The first Saturday</option>
|
||
<option value="day">The first day</option>
|
||
<option value="weekday">The first weekday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-weekly-additional">
|
||
<label for="saved-search-weekly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day">
|
||
<option value="Sunday">Sunday</option>
|
||
<option value="Monday">Monday</option>
|
||
<option value="Tuesday">Tuesday</option>
|
||
<option value="Wednesday">Wednesday</option>
|
||
<option value="Thursday">Thursday</option>
|
||
<option value="Friday">Friday</option>
|
||
<option value="Saturday">Saturday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-report" class="action-panel-label">
|
||
Report format:
|
||
</label>
|
||
<select id="saved-search-report" class="no-border-panel-selector saved-search-report">
|
||
<option value="DocSum">Summary</option>
|
||
<option value="DocSumText">Summary (text)</option>
|
||
<option value="Abstract">Abstract</option>
|
||
<option value="AbstractText">Abstract (text)</option>
|
||
<option value="MEDLINE">PubMed</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-amount" class="action-panel-label">
|
||
Send at most:
|
||
</label>
|
||
<select id="saved-search-amount" class="no-border-panel-selector saved-search-amount">
|
||
<option value="1">1 item</option>
|
||
<option value="5" selected>5 items</option>
|
||
<option value="10">10 items</option>
|
||
<option value="20">20 items</option>
|
||
<option value="50">50 items</option>
|
||
<option value="100">100 items</option>
|
||
<option value="200">200 items</option>
|
||
</select>
|
||
</div>
|
||
<div>
|
||
<input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result">
|
||
<label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox">
|
||
Send even when there aren't any new results
|
||
</label>
|
||
</div>
|
||
<div class="action-panel-control-wrap option-text-in-email-wrap">
|
||
<label for="saved-search-email-text" class="action-panel-label">
|
||
Optional text in email:
|
||
</label>
|
||
<textarea name="saved-search-email-text"
|
||
id="saved-search-email-text"
|
||
class="saved-search-email-text"></textarea>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Save
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your saved search' panel"
|
||
ref="linksrc=close_saved_search_panel"
|
||
aria-controls="saved-search-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Create a file for external citation management software
|
||
</h2>
|
||
<form id="citation-manager-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
|
||
|
||
<input name="results-format" type="hidden" value="pubmed"/>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Send citations to citation manager' panel"
|
||
ref="linksrc=close_citation_manager_panel"
|
||
aria-controls="citation-manager-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your RSS Feed
|
||
</h2>
|
||
|
||
<form id="rss-action-panel-form"
|
||
class="rss-action-panel-form action-panel-content action-form"
|
||
data-create-rss-feed-url="/create-rss-feed-url/"
|
||
data-search-form-term-value="">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="rss-name" class="action-panel-label required-field-asterisk">
|
||
Name of RSS Feed:
|
||
</label>
|
||
<input maxlength="200"
|
||
placeholder="Name"
|
||
type="text"
|
||
name="rss-name"
|
||
id="rss-name"
|
||
class="rss-name"
|
||
value=''
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="rss-limit-wrap">
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="rss-limit" class="action-panel-label">
|
||
Number of items displayed:
|
||
</label>
|
||
<select id="rss-limit" class="no-border-panel-selector rss-limit">
|
||
<option value="5">5</option>
|
||
<option value="10">10</option>
|
||
<option value="15" selected="selected">15</option>
|
||
<option value="20">20</option>
|
||
<option value="50">50</option>
|
||
<option value="100">100</option>
|
||
</select>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Creating..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Create RSS
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your RSS' panel"
|
||
ref="linksrc=close_rss_panel"
|
||
aria-controls="rss-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap rss-link-copy-wrap">
|
||
<label for="rss-link" class="usa-sr-only">RSS Link</label>
|
||
<input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link">
|
||
<button
|
||
type="button"
|
||
disabled
|
||
class="rss-link-copy-button disabled"
|
||
data-ga-category="save_share"
|
||
data-ga-action="rss"
|
||
data-ga-label="copy">
|
||
Copy
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="article-page" id="article-page" data-article-pmid="27043185">
|
||
<aside class="page-sidebar">
|
||
<div class="inner-wrap">
|
||
|
||
<div class="full-text-links">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Full text links
|
||
</h3>
|
||
<div class="full-text-links-list">
|
||
<a class="link-item
|
||
|
||
dialog-focus"
|
||
href="https://doi.org/10.1002/14651858.CD004085.pub4"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=3058&itool=Abstract-def&log$=linkouticon&uid=27043185&db=pubmed&nlmid=100909747"
|
||
title="See full text options at Wiley"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="Wiley"
|
||
data-ga-label="27043185"
|
||
><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-7331-42-Cochrane_Library_Logo_RGB_120x30.jpg" alt="Wiley full text link"><span class="text">
|
||
|
||
Wiley
|
||
|
||
</span></a><a class="link-item
|
||
pmc
|
||
"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/pmid/27043185/"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=True&PrId=3494&itool=Abstract-def&log$=linkouticon&uid=27043185&db=pubmed&nlmid=100909747"
|
||
title="Free full text at PubMed Central"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="PMC"
|
||
data-ga-label="27043185"
|
||
><span class="text">
|
||
|
||
Free PMC article
|
||
|
||
</span></a>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="short-view">
|
||
<a href="#" class="full-text-links-button full-text-links-dialog-trigger">
|
||
Full text links
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger"
|
||
aria-label="Open dialog with citation text in different styles"
|
||
data-ga-category="save_share"
|
||
data-ga-action="cite"
|
||
data-ga-label="open"
|
||
data-all-citations-url="/27043185/citations/"
|
||
data-citation-style="nlm"
|
||
data-pubmed-format-link="/27043185/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="27043185" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger"
|
||
aria-label="Save article in MyNCBI collections."
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_button"
|
||
data-collections-open-dialog-enabled="false"
|
||
data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F27043185%2F%23open-collections-dialog"
|
||
data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog"
|
||
class="dialog collections-dialog"
|
||
aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="39WNYJy8IXPfdqdqSr9HcdgtY4hzFLc8kWGSBz1uiyCJ7RjgvKMJGlM7w8ZLymKs"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio"
|
||
id="collections-action-dialog-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio"
|
||
id="collections-action-dialog-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label><input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-dialog-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label><select id="collections-action-dialog-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="add">
|
||
Add
|
||
</button><button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger"
|
||
title="Open dialog with more actions to take"
|
||
ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region"><button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title">
|
||
Display options
|
||
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</a></li></ul></div></div></div><span class="period">. </span><span class="cit">2016 Apr 4;4(4):CD004085.</span>
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High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome
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</h1>
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<h1 class="heading-title">
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High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome
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<strong class="sub-title">
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Background:
|
||
</strong>
|
||
|
||
High-frequency oscillation (HFO) is an alternative to conventional mechanical ventilation that is sometimes used to treat people with acute respiratory distress syndrome, but effects on oxygenation, mortality and adverse clinical outcomes are uncertain. This review was originally published in 2004 and was updated in 2013 and again in 2015.
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Objectives:
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To determine the effects of HFO compared to conventional mechanical ventilation on physiological outcomes, clinical outcomes, and mortality when used for the treatment of acute respiratory distress syndrome (ARDS).
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Search methods:
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We electronically searched the Cochrane Central Register of Controlled Trials (CENTRAL) (Ovid), MEDLINE (Ovid), EMBASE (Ovid), and ISI, from inception to December 2015. We conducted the original search in 2002. We manually searched reference lists from included studies and review articles; searched conference proceedings of the American Thoracic Society (1994 to 2015), Society of Critical Care Medicine (1994 to 2015), European Society of Intensive Care Medicine (1994 to 2015), and American College of Chest Physicians (1994 to 2015); contacted clinical experts in the field; and searched for unpublished and ongoing trials in clinicaltrials.gov and controlled-trials.com.
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|
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<strong class="sub-title">
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Selection criteria:
|
||
</strong>
|
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|
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Randomized controlled trials (RCTs) comparing treatment using HFO with conventional mechanical ventilation for children and adults diagnosed with ARDS.
|
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</p>
|
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|
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Data collection and analysis:
|
||
</strong>
|
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|
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Three review authors independently extracted data on clinical, physiological, and safety outcomes according to a predefined protocol. We contacted investigators of all included studies to clarify methods and obtain additional data. We used random-effects models in the analyses.
|
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</p>
|
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|
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<p>
|
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<strong class="sub-title">
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Main results:
|
||
</strong>
|
||
|
||
We include 10 RCTs (n = 1850); almost all participants had moderate or severe ARDS. For the primary analysis, the risk of bias was low in three studies and unclear in five studies; the overall quality of evidence was very low due to imprecision, inconsistency, indirectness and methodologic limitations. In participants randomized to HFO, there was no significant difference in hospital or 30-day mortality (risk ratio (RR) 0.92, 95% confidence interval (CI) 0.72 to 1.16; P = 0.46, I² = 66%; 8 trials, 1779 participants, 807 deaths) compared with conventional ventilation. One large multicentre RCT was terminated early because of increased mortality in participants randomized to HFO compared to mechanical ventilation with low tidal volume and high positive end expiratory pressure, with HFO reserved only as a rescue therapy. We found substantial between-trial statistical heterogeneity (I² = 0% to 66%) for clinical outcomes, including mortality.
|
||
</p>
|
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||
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<p>
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||
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<strong class="sub-title">
|
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Authors' conclusions:
|
||
</strong>
|
||
|
||
The findings of this systematic review suggest that HFO does not reduce hospital and 30-day mortality due to ARDS; the quality of evidence was very low. Our findings do not support the use of HFO as a first-line strategy in people undergoing mechanical ventilation for ARDS.
|
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|
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Conflict of interest statement
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</h2>
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<div class="statement">
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<p xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:p1="http://pubmed.gov/pub-one">All authors have completed the Cochrane online conflicts of interest form and declare the following:</p>
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|
||
<p xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:p1="http://pubmed.gov/pub-one">Sachin Sud: nothing to declare. Maneesh Sud: nothing to declare. Jan O Friedrich: no financial interests to declare; Dr. Friedrich is a co‐investigators for the Canadian Institutes of Health Research (CIHR) funded OSCILLATE study, which was included in this review (Ferguson 2013). CareFusion (formerly SensorMedics) is providing study oscillators to some of the hospitals involved in the OSCILLATE study for the duration of the study. Hannah Wunsch: nothing to declare. Maureen O Meade:no financial interests to declare; Dr. Meade is a primary investigator for the Canadian Institutes of Health Research (CIHR) funded OSCILLATE study, which was included in this review (Ferguson 2013). CareFusion (formerly SensorMedics) is providing study oscillators to some of the hospitals involved in the OSCILLATE study for the duration of the study. Niall D Ferguson:no financial interests to declare; Dr. Ferguson is a primary investigator for the Canadian Institutes of Health Research (CIHR) funded OSCILLATE study, which was included in this review (Ferguson 2013). CareFusion (formerly SensorMedics) is providing study oscillators to some of the hospitals involved in the OSCILLATE study for the duration of the study. Neill KJ Adhikari: no financial interests to declare; Dr. Adhikari is a co‐investigators for the Canadian Institutes of Health Research (CIHR) funded OSCILLATE study, which was included in this review (Ferguson 2013). CareFusion (formerly SensorMedics) is providing study oscillators to some of the hospitals involved in the OSCILLATE study for the duration of the study.</p>
|
||
|
||
<p xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:p1="http://pubmed.gov/pub-one">Four of the seven authors (JOF, NKJA, NDF, MOM) co‐authored one of the included studies Ferguson 2013 and were not involved in the acquisition and interpretation of data, or the assessment of risk of bias for this study (which was performed by SS and MS). JOF verified the calculation of ratio of means (which was first performed independently by SS and MS), for physiologic outcomes for all studies, including Ferguson 2013.</p>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="figures" id="figures">
|
||
<h2 class="title">
|
||
Figures
|
||
</h2>
|
||
|
||
<div class="figures-list" id="slides-container"
|
||
itemscope itemtype="http://schema.org/ImageGallery">
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="0"
|
||
data-label-slug="1">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/5c34908b8c57/nCD004085-AFig-FIG01.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-0"
|
||
role="button"
|
||
data-image-width="587"
|
||
data-image-height="555"
|
||
data-image-alt="1"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0001">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-0"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/9b7363999232/nCD004085-AFig-FIG01.gif"
|
||
alt="1" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="587">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="555">
|
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|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Study flow diagram for the updated… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Study flow diagram for the updated literature search (from 2011 to Dec 2015, see… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-0" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Study flow diagram for the updated literature search (from 2011 to Dec 2015, see also Results of the search)</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="1"
|
||
data-label-slug="2">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/e84319c631a4/nCD004085-AFig-FIG02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-1"
|
||
role="button"
|
||
data-image-width="338"
|
||
data-image-height="582"
|
||
data-image-alt="2"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0002">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-1"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/59dc9a11aa24/nCD004085-AFig-FIG02.gif"
|
||
alt="2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="338">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="582">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Methodological quality summary: review authors' judgements… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Methodological quality summary: review authors' judgements about each methodological quality item for each included… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-1" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
2
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Methodological quality summary: review authors' judgements about each methodological quality item for each included study.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="2"
|
||
data-label-slug="3">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/9706522d6bb2/nCD004085-AFig-FIG03.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-2"
|
||
role="button"
|
||
data-image-width="547"
|
||
data-image-height="231"
|
||
data-image-alt="3"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0003">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-2"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/abe0666f66ba/nCD004085-AFig-FIG03.gif"
|
||
alt="3" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="547">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="231">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Methodological quality graph: review authors' judgements… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-2" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Methodological quality graph: review authors' judgements about each methodological quality item presented as percentages across all included studies.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="3"
|
||
data-label-slug="4">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/049646b8c346/nCD004085-AFig-FIG04.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-3"
|
||
role="button"
|
||
data-image-width="584"
|
||
data-image-height="256"
|
||
data-image-alt="4"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0004">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-3"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/2e85bcbcc737/nCD004085-AFig-FIG04.gif"
|
||
alt="4" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="584">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="256">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Forest plot of comparison: 1 Mortality,… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Forest plot of comparison: 1 Mortality, outcome: 1.1 Hospital or 30‐day mortality. (HFO =… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-3" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
4
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Forest plot of comparison: 1 Mortality, outcome: 1.1 Hospital or 30‐day mortality. (HFO = high frequency oscillation, CMV = conventional mechanical ventilation)</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="4"
|
||
data-label-slug="5">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/1b013a9fb61d/nCD004085-AFig-FIG05.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-4"
|
||
role="button"
|
||
data-image-width="584"
|
||
data-image-height="234"
|
||
data-image-alt="5"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0005">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-4"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/7f8ae8b1704a/nCD004085-AFig-FIG05.gif"
|
||
alt="5" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="584">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="234">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 5 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Forest plot of comparison: 2 Adverse… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 5 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Forest plot of comparison: 2 Adverse events, outcome: 2.1 Treatment failure (intractable hypoxia, hypotension,… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-4" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
5
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Forest plot of comparison: 2 Adverse events, outcome: 2.1 Treatment failure (intractable hypoxia, hypotension, acidosis, hypercapnoea requiring discontinuation of study intervention). (HFO = high frequency oscillation, CMV = conventional mechanical ventilation)</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
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|
||
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|
||
data-slide-index="5"
|
||
data-label-slug="11">
|
||
<a class="figure-link"
|
||
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|
||
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|
||
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|
||
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|
||
data-image-width="566"
|
||
data-image-height="229"
|
||
data-image-alt="1.1"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0006">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-5"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/e4df33592fe9/nCD004085-CMP-001-01.gif"
|
||
alt="1.1" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="229">
|
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|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 1… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 1 Hospital or 30‐day mortality. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-5" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.1. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 1 Hospital or 30‐day mortality.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="6"
|
||
data-label-slug="12">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/b3391a65c023/nCD004085-CMP-001-02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-6"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="229"
|
||
data-image-alt="1.2"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0007">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-6"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/f7e22dde645b/nCD004085-CMP-001-02.gif"
|
||
alt="1.2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="229">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 2… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 2 Hospital or 30‐day mortality (Bollen 2005 and Mentzelopoulos… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-6" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.2. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 2 Hospital or 30‐day mortality (Bollen 2005 and Mentzelopoulos 2012 participants lost to follow‐up censored).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="7"
|
||
data-label-slug="13">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/0c37e6e005f7/nCD004085-CMP-001-03.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-7"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="229"
|
||
data-image-alt="1.3"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0008">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-7"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/6bc499fa43de/nCD004085-CMP-001-03.gif"
|
||
alt="1.3" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="229">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 3… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 3 Hospital or 30‐day mortality (Shah 2004 post‐randomization withdrawals… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-7" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.3. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 3 Hospital or 30‐day mortality (Shah 2004 post‐randomization withdrawals included).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="8"
|
||
data-label-slug="14">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/863591a42ed5/nCD004085-CMP-001-04.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-8"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="296"
|
||
data-image-alt="1.4"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0009">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-8"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/f092452bee65/nCD004085-CMP-001-04.gif"
|
||
alt="1.4" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="296">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 4… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 4 Hospital or 30‐day mortality: adult versus paediatric trials. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-8" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.4. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 4 Hospital or 30‐day mortality: adult versus paediatric trials.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="9"
|
||
data-label-slug="15">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/bb848dcd8d55/nCD004085-CMP-001-05.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-9"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="296"
|
||
data-image-alt="1.5"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0010">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-9"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/e95e803aa2cc/nCD004085-CMP-001-05.gif"
|
||
alt="1.5" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="296">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.5. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 5… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.5. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 5 Hospital or 30‐day mortality: lung‐protective ventilation mandatory vs… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-9" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.5. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 5 Hospital or 30‐day mortality: lung‐protective ventilation mandatory vs non‐mandatory.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="10"
|
||
data-label-slug="16">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/b591816f9957/nCD004085-CMP-001-06.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-10"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="169"
|
||
data-image-alt="1.6"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0011">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-10"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/769a7361f8d5/nCD004085-CMP-001-06.gif"
|
||
alt="1.6" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="169">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.6. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 6… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1.6. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 1 Mortality, Outcome 6 Hospital or 30‐day mortality (trials with low risk… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-10" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1.6. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 1 Mortality, Outcome 6 Hospital or 30‐day mortality (trials with low risk of bias).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="11"
|
||
data-label-slug="21">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/334b8a2e76de/nCD004085-CMP-002-01.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-11"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="193"
|
||
data-image-alt="2.1"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0012">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-11"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/111fb518a2d3/nCD004085-CMP-002-01.gif"
|
||
alt="2.1" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="193">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 2 Ventilator dependency, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 2 Ventilator dependency, Outcome 1 Duration of mechanical ventilation. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-11" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
2.1. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 2 Ventilator dependency, Outcome 1 Duration of mechanical ventilation.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="12"
|
||
data-label-slug="22">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/79b9cdf7865e/nCD004085-CMP-002-02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-12"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="131"
|
||
data-image-alt="2.2"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0013">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-12"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/d37955ef9a29/nCD004085-CMP-002-02.gif"
|
||
alt="2.2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="131">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 2 Ventilator dependency, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 2 Ventilator dependency, Outcome 2 Ventilator‐free days. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-12" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
2.2. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 2 Ventilator dependency, Outcome 2 Ventilator‐free days.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="13"
|
||
data-label-slug="31">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/6aa93ae361d7/nCD004085-CMP-003-01.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-13"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="205"
|
||
data-image-alt="3.1"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0014">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-13"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/369be75c942a/nCD004085-CMP-003-01.gif"
|
||
alt="3.1" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="205">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome 1 Treatment failure (intractable hypoxia, hypotension, acidosis, hypercapnoea… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-13" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3.1. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 3 Adverse events, Outcome 1 Treatment failure (intractable hypoxia, hypotension, acidosis, hypercapnoea requiring discontinuation of study intervention).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="14"
|
||
data-label-slug="32">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/2769bc7546cf/nCD004085-CMP-003-02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-14"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="217"
|
||
data-image-alt="3.2"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0015">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-14"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/454ea5c644fc/nCD004085-CMP-003-02.gif"
|
||
alt="3.2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="217">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome 2 Barotrauma. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-14" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3.2. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 3 Adverse events, Outcome 2 Barotrauma.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="15"
|
||
data-label-slug="33">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/07f579ee09d5/nCD004085-CMP-003-03.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-15"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="181"
|
||
data-image-alt="3.3"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0016">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-15"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/8ced10dbc45a/nCD004085-CMP-003-03.gif"
|
||
alt="3.3" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="181">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome 3 Hypotension. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-15" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3.3. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 3 Adverse events, Outcome 3 Hypotension.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="16"
|
||
data-label-slug="34">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/711927bb004f/nCD004085-CMP-003-04.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-16"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="193"
|
||
data-image-alt="3.4"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0017">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-16"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/69618318cc81/nCD004085-CMP-003-04.gif"
|
||
alt="3.4" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="193">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome 4 Hypotension (Shah included). </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-16" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3.4. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 3 Adverse events, Outcome 4 Hypotension (Shah included).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="17"
|
||
data-label-slug="35">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/f133b9f71339/nCD004085-CMP-003-05.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-17"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="154"
|
||
data-image-alt="3.5"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0018">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-17"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/eefa701a7a8f/nCD004085-CMP-003-05.gif"
|
||
alt="3.5" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="154">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.5. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 3.5. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 3 Adverse events, Outcome 5 ETT obstruction. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-17" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
3.5. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 3 Adverse events, Outcome 5 ETT obstruction.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="18"
|
||
data-label-slug="41">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/fd1f6e268be3/nCD004085-CMP-004-01.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-18"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="453"
|
||
data-image-alt="4.1"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0019">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-18"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/77721a583017/nCD004085-CMP-004-01.gif"
|
||
alt="4.1" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="453">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.1. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio of means), Outcome 1 PaO₂/FiO₂ (ratio of means). </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-18" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
4.1. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 4 Physiological endpoints (ratio of means), Outcome 1 PaO₂/FiO₂ (ratio of means).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item tail"
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="19"
|
||
data-label-slug="42">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/6f23407caff1/nCD004085-CMP-004-02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-19"
|
||
role="button"
|
||
data-image-width="566"
|
||
data-image-height="441"
|
||
data-image-alt="4.2"
|
||
data-pmc-id="PMC6516956"
|
||
data-figure-id="CD004085-fig-0020">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-19"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/502f/6516956/2ab6ae1d82a9/nCD004085-CMP-004-02.gif"
|
||
alt="4.2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="566">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="441">
|
||
|
||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.2. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio of means), Outcome 2 Oxygenation index (ratio of… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
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<strong class="figure-label">
|
||
4.2. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 4 Physiological endpoints (ratio of means), Outcome 2 Oxygenation index (ratio of means).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
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<strong class="figure-label">
|
||
<p> 4.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio… </p></div>
|
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|
||
|
||
|
||
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||
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<strong class="figure-label">
|
||
<p> 4.3. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio of means), Outcome 3 PaCO₂ (ratio of means). </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
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<figcaption id="figure-caption-20" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
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||
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<strong class="figure-label">
|
||
4.3. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 4 Physiological endpoints (ratio of means), Outcome 3 PaCO₂ (ratio of means).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
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<figure class="figure-item tail"
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itemscope itemtype="http://schema.org/ImageObject"
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data-image-alt="4.4"
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data-pmc-id="PMC6516956"
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data-figure-id="CD004085-fig-0022">
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<img class="figure-thumb" itemprop="thumbnail"
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|
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<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
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<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 4.4. Analysis </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Comparison 4 Physiological endpoints (ratio of means), Outcome 4 Mean airway pressure (ratio… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-21" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
4.4. Analysis
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Comparison 4 Physiological endpoints (ratio of means), Outcome 4 Mean airway pressure (ratio of means).</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
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</div>
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<h2 class="title">
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Update of
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<ul class="item-list usa-unstyled-list">
|
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|
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|
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<li class="full-docsum">
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<div class="docsum-content" style="display:inline;">
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<a class="docsum-title"
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High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome.
|
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|
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</a>
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<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Sud S, Sud M, Friedrich JO, Wunsch H, Meade MO, Ferguson ND, Adhikari NK.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Sud S, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Cochrane Database Syst Rev. 2013 Feb 28;(2):CD004085. doi: 10.1002/14651858.CD004085.pub3.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Cochrane Database Syst Rev. 2013.</span>
|
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|
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|
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|
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<span class="docsum-comments-correction">
|
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<span class="correction-label citation-part">Update in: </span>
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data-ga-label="linked-update">Cochrane Database Syst Rev. 2016 Apr 04;4:CD004085. doi: 10.1002/14651858.CD004085.pub4.</a>
|
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</span>
|
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|
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|
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<span class="citation-part">PMID: <span class="docsum-pmid">23450549</span></span>
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|
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<span class="correction-label spaced-citation-item citation-part">Updated.</span>
|
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|
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<span class="publication-type spaced-citation-item citation-part">Review.</span>
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</div>
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</ul>
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<div class="references" id="references">
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<h2 class="title">
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References
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</h2>
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<div id='top-references-list' class="references-lists-container">
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<div class="refs-list">
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<h4 class="refs-list-title">References to studies included in this review</h4>
|
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||
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||
|
||
|
||
<div class="refs-list">
|
||
|
||
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||
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<h5 class="refs-list-title">Arnold 1994 {published and unpublished data}</h5>
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<ol id="top-references-list-2" class="references-list">
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Arnold JH, Hanson JH, Toro‐Figuero LO, Gutierrez J, Berens RJ, Anglin DL. Prospective, randomized comparison of high‐frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Critical Care Medicine 1994;22(10):1530‐9. [MEDLINE: ]
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-
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<a
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<div class="refs-list">
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<h5 class="refs-list-title">Bollen 2005 {published and unpublished data}</h5>
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<ol id="top-references-list-3" class="references-list">
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Bollen CW, Well GT, Sherry T, Beale RJ, Shah S, Findlay G, et al. High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial. Critical Care 2005;9(4):R430‐9. [MEDLINE: ]
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-
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<a
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class="reference-link"
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href="https://pmc.ncbi.nlm.nih.gov/articles/PMC1269459/"
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<div class="refs-list">
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<h5 class="refs-list-title">Demory 2007 {published and unpublished data}</h5>
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||
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<ol id="top-references-list-4" class="references-list">
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<ol class="references-and-notes-list">
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Demory D, Michelet P, Arnal JM, Donati S, Forel JM, Gainnier M, et al. High‐frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygenation. Critical Care Medicine 2007;35(1):106‐11. [MEDLINE: ]
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|
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-
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<a
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</div>
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||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Derdak 2002 {published and unpublished data}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-5" class="references-list">
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<li>
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<ol class="references-and-notes-list">
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Derdak S, Mehta S, Stewart TE, Smith T, Rogers M, Buchman TG, et al. High‐frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. American Journal of Respiratory and Critical Care Medicine 2002;166(6):801‐8. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
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<a
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</div>
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||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Ferguson 2013 {published data only}</h5>
|
||
|
||
|
||
|
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<ol id="top-references-list-6" class="references-list">
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Ferguson N, Mehta S, Slutsky A, Stewart T, Hand L, Zhou Q, et al. Conversion from ventilation to high frequency oscillation ‐ physiologic responses in a pilot randomized trial. American Journal of Respiratory and Critical Care Medicine 2009;179:A3651.
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value="1">
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|
||
Ferguson ND, Cook DJ, Guyatt GH, Mehta S, Hand L, Austin P, et al. High‐frequency oscillation in early acute respiratory distress syndrome. New England Journal of Medicine 2013;368(9):795‐805.
|
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|
||
|
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|
||
-
|
||
<a
|
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class="reference-link"
|
||
href="/23339639/"
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|
||
class="skip-numbering"
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||
value="1">
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|
||
Hand L, Matte A, Marie C, Ethier C, Lazosky L, Clarke F, et al. Results of a pilot randomized trial of High Frequency Oscillation in adults with Acute Respiratory Distress Syndrome. Critical Care Canada Forum (<a class="external-link-urlize" href="http://www.criticalcarecanada.com/abstracts/2009/high‐frequency‐oscillation.php" rel="nofollow noopener" target="_blank">www.criticalcarecanada.com/abstracts/2009/high‐frequency‐oscillation.php</a>). Toronto, Canada, 2009.
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value="1">
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||
Meade MO, Cook DJ, Mehta S, Arabi YM, Keenan S, Ronco JJ, et al. A multicentre pilot randomized trial of high frequency oscillation in acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine 2009; Vol. 179:A1559.
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||
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|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
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||
|
||
<h5 class="refs-list-title">Mentzelopoulos 2012 {published and unpublished data}</h5>
|
||
|
||
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||
|
||
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||
|
||
<ol id="top-references-list-7" class="references-list">
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||
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||
value="1">
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||
|
||
Malachias S, Kokkoris S, Zakynthinos S, Mentzelopoulos SD. High frequency oscillation and tracheal gas insufflations for severe Acute Respiratory Distress Syndrome: Results from a single‐center, phase II, randomized controlled trial [NCT00416260]. Intensive Care Medicine 2009;35 Suppl 1:S6.
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<li
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||
class="skip-numbering"
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||
value="1">
|
||
|
||
Mentzelopoulos SD, Malachias S, Tzoufi M, Markaki V, Zervakis D, Pitaridis M. High frequency oscillation and tracheal gas insufflation for severe acute respiratory distress syndrome. Intensive Care Medicine 2007;33 Suppl 2:S142.
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class="skip-numbering"
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||
value="1">
|
||
|
||
Mentzelopoulos SD, Malachias S, Zintzaras E, Kokkoris S, Zakynthinos E, Makris D, et al. Intermittent recruitment with high‐frequency oscillation/tracheal gas insufflation in acute respiratory distress syndrome. European Respiratory Journal 2012;39(3):635‐47.
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||
|
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|
||
|
||
-
|
||
<a
|
||
class="reference-link"
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href="/21885390/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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data-ga-category="reference"
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||
data-ga-action="21885390"
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||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Papazian 2005 {published and unpublished data}</h5>
|
||
|
||
|
||
|
||
|
||
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||
<ol id="top-references-list-8" class="references-list">
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||
value="1">
|
||
|
||
Papazian L, Gainnier M, Marin V, Donati S, Arnal JM, Demory D, et al. Comparison of prone positioning and high‐frequency oscillatory ventilation in patients with acute respiratory distress syndrome. Critical Care Medicine 2005;33(10):2162‐71. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/16215365/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
|
||
data-ga-action="16215365"
|
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>
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||
PubMed
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|
||
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||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Samransamruajkit 2005 {published and unpublished data}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-9" class="references-list">
|
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||
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||
value="1">
|
||
|
||
Samransamruajkit R, Prapphal N, Deelodegenavong J, Poovorawan Y. Plasma soluble intercellular adhesion molecule‐1 (sICAM‐1) in pediatric ARDS during high frequency oscillatory ventilation: a predictor of mortality. Asian Pacific Journal of Allergy and Immunology 2005; Vol. 23, issue 4:181‐8. [MEDLINE: ]
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/16572737/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
|
||
data-ga-action="16572737"
|
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>
|
||
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||
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||
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||
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|
||
|
||
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|
||
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|
||
value="1">
|
||
|
||
Samransamruajkit R, Prapphal N, Deerojanawong J, Vanapongtipagorn P, Poovorawan Y. Soluble Intercellular Adhesion Molecule‐1 (sICAM‐1) in pediatric ARDS during high frequency oscillatory ventilation; Randomized controlled trial, a predictor of mortality. American Journal of Respiratory and Critical Care Medicine 2003;167:A999.
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/0/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="0"
|
||
>
|
||
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|
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|
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|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Shah 2004 {unpublished data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-10" class="references-list">
|
||
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||
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||
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||
|
||
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||
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|
||
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||
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|
||
value="1">
|
||
|
||
Shah SB, Findlay GP, Jackson SK, Smithies MN. Prospective study comparing HFOV versus CMV in patients with ARDS. Intensive Care Medicine 2004;30 Suppl 1:S84.
|
||
|
||
|
||
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||
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||
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|
||
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|
||
|
||
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||
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|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Shah SB, Jackson SK, Findlay GP, Smithies MN. Prospective study comparing high frequency oscillatory ventilation (HFOV) versus conventional (CMV) in patients with acute respiratory distress syndrome (ARDS) [abstract]. Proceedings of the American Thoracic Society 2005;2:A847.
|
||
|
||
|
||
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|
||
|
||
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|
||
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|
||
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||
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|
||
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|
||
|
||
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|
||
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|
||
value="1">
|
||
|
||
Shah SB, Jackson SK, Findlay GP, Smithies MN. Ventilator induced lung injury comparing high frequency oscillator ventilation versus conventional mechanical ventilation [abstract]. Proceedings of the American Thoracic Society 2005;2:A251.
|
||
|
||
|
||
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|
||
|
||
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|
||
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||
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||
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||
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|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Young 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-11" class="references-list">
|
||
|
||
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||
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||
|
||
|
||
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|
||
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|
||
|
||
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|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Young D, Lamb SE, Shah S, MacKenzie I, Tunnicliffe W, Lall R, et al. High‐frequency oscillation for acute respiratory distress syndrome. New England Journal of Medicine 2013;368(9):806‐13.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/23339638/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
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|
||
data-ga-action="23339638"
|
||
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|
||
PubMed
|
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||
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||
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||
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|
||
|
||
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|
||
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|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Young JD. Conventional positive pressure ventilation or High Frequency Oscillatory Ventilation (HFOV) for adults with acute respiratory distress syndrome. <a class="external-link-urlize" href="http://www.isrctn.com/ISRCTN10416500" rel="nofollow noopener" target="_blank">www.isrctn.com/ISRCTN10416500</a> [accessed 1 August 2010].
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||
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||
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||
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||
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||
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||
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|
||
</div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">References to studies excluded from this review</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Carlon 1983 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-13" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
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|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Carlon GC, Howland WS, Ray C, Miodownik S, Griffin JP, Groeger JS. High‐frequency jet ventilation. A prospective randomized evaluation. Chest 1983;84(5):551‐9. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/6628006/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="6628006"
|
||
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|
||
PubMed
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|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Dobyns 2002 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-14" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
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||
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||
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||
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|
||
value="1">
|
||
|
||
Dobyns EL, Anas NG, Fortenberry JD, Deshpande J, Cornfield DN, Tasker RC, et al. Interactive effects of high‐frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. Critical Care Medicine 2002;30(11):2425‐9. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/12441749/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="12441749"
|
||
>
|
||
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|
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||
|
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||
|
||
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|
||
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|
||
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Fessler 2008 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-15" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
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|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Fessler HE, Hager DN, Brower RG. Feasibility of very high‐frequency ventilation in adults with acute respiratory distress syndrome. Critical Care Medicine 2008;36(4):1043‐8. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/18379227/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="18379227"
|
||
>
|
||
PubMed
|
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|
||
|
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|
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|
||
|
||
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||
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||
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|
||
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||
|
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|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Hurst 1984 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-16" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Hurst JM, DeHaven CB. Adult respiratory distress syndrome: improved oxygenation during high‐frequency jet ventilation/continuous positive airway pressure. Surgery 1984;96(4):764‐9. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/6385318/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="6385318"
|
||
>
|
||
PubMed
|
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|
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|
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|
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|
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|
||
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|
||
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|
||
|
||
|
||
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Hurst 1990 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-17" class="references-list">
|
||
|
||
|
||
|
||
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||
<li>
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||
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|
||
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||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Hurst JM, Branson RD, Davis K, Jr, Barrette RR, Adams KS. Comparison of conventional mechanical ventilation and high‐frequency ventilation. A prospective, randomized trial in patients with respiratory failure. Annals of Surgery 1990;211(4):486‐91. [MEDLINE: ]
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/PMC1358037/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
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||
data-ga-action="PMC1358037"
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|
||
PMC
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</a>
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||
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||
-
|
||
<a
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||
class="reference-link"
|
||
href="/2181951/"
|
||
ref="linksrc=references_link&ordinalpos=2"
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||
data-ga-category="reference"
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||
data-ga-action="2181951"
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PubMed
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|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Mentzelopoulos 2007a {published data only}</h5>
|
||
|
||
|
||
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||
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||
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||
<ol id="top-references-list-18" class="references-list">
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||
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||
value="1">
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||
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||
Mentzelopoulos SD, Roussos C, Koutsoukou A, Sourlas S, Malachias S, Lachana A, et al. Acute effects of combined high‐frequency oscillation and tracheal gas insufflation in severe acute respiratory distress syndrome. Critical Care Medicine 2007;35(6):1500‐8. [MEDLINE: ]
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||
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||
|
||
|
||
-
|
||
<a
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||
class="reference-link"
|
||
href="/17440419/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="17440419"
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||
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||
PubMed
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||
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||
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||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Mentzelopoulos 2010 {published data only}</h5>
|
||
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||
|
||
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||
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||
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||
<ol id="top-references-list-19" class="references-list">
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<li
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||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Mentzelopoulos SD, Malachias S, Kokkoris S, Roussos C, Zakynthinos SG. Comparison of high‐frequency oscillation and tracheal gas insufflation versus standard high‐frequency oscillation at two levels of tracheal pressure. Critical Care Medicine 2010;36(5):810‐6. [MEDLINE: ]
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/20232047/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
|
||
data-ga-action="20232047"
|
||
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|
||
PubMed
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||
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||
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||
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||
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||
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||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Vrettou 2014 {published data only}</h5>
|
||
|
||
|
||
|
||
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||
|
||
<ol id="top-references-list-20" class="references-list">
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||
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||
<li
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||
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||
value="1">
|
||
|
||
Vrettou CS, Zakynthinos SG, Malachias S, Mentzelopoulos SD. The effect of high‐frequency oscillatory ventilation combined with tracheal gas insufflation on extravascular lung water in patients with acute respiratory distress syndrome: a randomized, crossover, physiologic study. Journal of Critical Care 2014;29(4):568‐73.
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/24814973/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
|
||
data-ga-action="24814973"
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||
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||
PubMed
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||
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||
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||
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||
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||
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||
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||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">Additional references</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Adhikari 2007</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-22" class="references-list">
|
||
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||
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||
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||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Adhikari NK, Burns KE, Friedrich JO, Granton JT, Cook DJ, Meade MO. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta‐analysis. BMJ 2007;334(7597):779. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/PMC1852043/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="PMC1852043"
|
||
>
|
||
PMC
|
||
</a>
|
||
|
||
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/17383982/"
|
||
ref="linksrc=references_link&ordinalpos=2"
|
||
data-ga-category="reference"
|
||
data-ga-action="17383982"
|
||
>
|
||
PubMed
|
||
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|
||
|
||
|
||
|
||
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||
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||
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||
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||
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||
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||
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||
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||
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Albuali 2007</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-23" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Albuali WH, Singh RN, Fraser DD, Seabrook JA, Kavanagh BP, Parshuram CS, et al. Have changes in ventilation practice improved outcome in children with acute lung injury?. Pediatric Critical Care Medicine 2007; Vol. 8, issue 4:324‐30. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/17545937/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="17545937"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
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||
|
||
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|
||
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||
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||
|
||
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Amato 1998</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-24" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Amato MB, Barbas CS, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi‐Filho G, et al. Effect of a protective‐ventilation strategy on mortality in the acute respiratory distress syndrome. New England Journal of Medicine 1998;338(6):347‐54. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/9449727/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="9449727"
|
||
>
|
||
PubMed
|
||
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|
||
|
||
|
||
|
||
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||
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||
|
||
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|
||
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|
||
|
||
|
||
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Angus 2001</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-25" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Angus DC, Musthafa AA, Clermont G, Griffin MF, Linde‐Zwirble WT, Dremsizov TT, et al. Quality‐adjusted survival in the first year after the acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine 2001;163(6):1389‐94. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/11371406/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="11371406"
|
||
>
|
||
PubMed
|
||
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|
||
|
||
|
||
|
||
|
||
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|
||
|
||
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|
||
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|
||
|
||
|
||
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">ARDS Definition Task Force 2012</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-26" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012;307(23):2526‐33.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/22797452/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="22797452"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">ARDS Network 2000</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-27" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. New England Journal of Medicine 2000;342(18):1301‐8. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/10793162/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="10793162"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Artigas 1998</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-28" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Artigas A, Bernard GR, Carlet J, Dreyfuss D, Gattinoni L, Hudson L, et al. The American‐European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. American Journal of Respiratory and Critical Care Medicine 1998;157(4 Pt 1):1332‐47. [MEDLINE: ]
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/9563759/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="9563759"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Begg 1994</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-29" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994;50(4):1088‐101. [MEDLINE: ]
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/7786990/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="7786990"
|
||
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|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
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|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Bein 2007</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-30" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Bein T, Ritzka M, Schmidt F, Taeger K. Positioning therapy in intensive care medicine in Germany. Results of a national survey [German]. Anaesthesist 2007;56(3):226‐31. [MEDLINE: ]
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||
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||
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||
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||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/17235540/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
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PMC
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Villar J, Kacmarek RM, Perez‐Mendez L, Aguirre‐Jaime A. A high positive end‐expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: a randomized, controlled trial. Critical Care Medicine 2006;34(5):1311‐8. [MEDLINE: ]
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<h5 class="refs-list-title">Wong 2006</h5>
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Wong SS, Wilczynski NL, Haynes RB. Developing optimal search strategies for detecting clinically sound treatment studies in EMBASE. Journal of the Medical Library Association 2006;94(1):41‐7. [MEDLINE: ]
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class="reference-link"
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<h4 class="refs-list-title">References to other published versions of this review</h4>
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Sud S, Adhikari N, Ferguson ND, Friedrich JO, Sud M, Meade MO. High‐frequency oscillatory ventilation for ARDS: a meta‐analysis. Critical Care Medicine 2007;35(12 Suppl):A225.
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<h5 class="refs-list-title">Sud 2010b</h5>
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Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, et al. High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta‐analysis. BMJ 2010;340:c2327. [1468‐5833: (Electronic)]
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<h5 class="refs-list-title">Sud 2013</h5>
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Sud S, Sud M, Friedrich JO, Meade MO, Ferguson ND, Wunsch H, et al. High‐frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. Cochrane Database of Systematic Reviews 2013, Issue 2. [DOI: 10.1002/14651858.CD004085.pub3]
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Wunsch H, Mapstone, J. High‐frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. Cochrane Database of Systematic Reviews 2003, Issue 1. [DOI: 10.1002/14651858.CD004085]
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<h5 class="refs-list-title">Wunsch 2004</h5>
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Wunsch H, Mapstone J. High‐frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. Cochrane Database of Systematic Reviews 2004, Issue 1. [DOI: 10.1002/14651858.CD004085.pub2]
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<div id="publication-types" class="publication-types keywords-section">
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Publication types
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||
data-pinger-ignore>
|
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Acute Lung Injury / therapy*
|
||
</button><div id="keyword-actions-mesh-terms-major-1"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Acute Lung Injury / therapy*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Acute+Lung+Injury%2Ftherapy%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Acute+Lung+Injury%2Ftherapy%22%5BMAJR%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Acute Lung Injury/therapy"[MAJR]"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-expanded="false"
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Adolescent
|
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</button><div id="keyword-actions-mesh-terms-2"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Adolescent"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Adolescent%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Adolescent%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Adolescent"[MeSH]"
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Adult"
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aria-expanded="false"
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Adult
|
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</button><div id="keyword-actions-mesh-terms-3"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Adult"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Adult"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Adult"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Adult"[MeSH]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""Adult"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword Child"
|
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tabindex="0"
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aria-controls="keyword-actions-mesh-terms-4"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Child
|
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</button><div id="keyword-actions-mesh-terms-4"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Child"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Child%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Child%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Child"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Child"
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Search in MeSH
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data-search-term=""Child"[MeSH]"
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data-ga-action="add_to_search"
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data-ga-label=""Child"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Child, Preschool"
|
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Child, Preschool
|
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</button><div id="keyword-actions-mesh-terms-5"
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Child, Preschool"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Child%2C+Preschool%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Child%2C+Preschool%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Child, Preschool"[MeSH]"
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Search in PubMed
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Child, Preschool"[MeSH]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""Child, Preschool"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
|
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aria-label="Toggle dropdown menu for keyword High-Frequency Ventilation / methods*"
|
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tabindex="0"
|
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aria-controls="keyword-actions-mesh-terms-major-6"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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High-Frequency Ventilation / methods*
|
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</button><div id="keyword-actions-mesh-terms-major-6"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword High-Frequency Ventilation / methods*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22High-Frequency+Ventilation%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc"
|
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data-href="/?term=%22High-Frequency+Ventilation%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="High-Frequency Ventilation/methods"[MAJR]"
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data-ga-category="search"
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data-ga-action="mesh_term"
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data-ga-label="High-Frequency Ventilation / methods*">
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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ref="linksrc=search_in_mesh_link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=High-Frequency+Ventilation"
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data-ga-category="search_mesh"
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data-ga-action="mesh_term_link"
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data-ga-label="High-Frequency Ventilation / methods*">
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
|
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ref="linksrc=add_to_search_link"
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role="button"
|
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data-search-term=""High-Frequency Ventilation/methods"[MAJR]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""High-Frequency Ventilation/methods"[MAJR]"
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href="#">
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword High-Frequency Ventilation / mortality"
|
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tabindex="0"
|
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aria-controls="keyword-actions-mesh-terms-7"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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High-Frequency Ventilation / mortality
|
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</button><div id="keyword-actions-mesh-terms-7"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword High-Frequency Ventilation / mortality"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22High-Frequency+Ventilation%2Fmortality%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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data-href="/?term=%22High-Frequency+Ventilation%2Fmortality%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="High-Frequency Ventilation/mortality"[MeSH]"
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data-ga-category="search"
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data-ga-action="mesh_term"
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data-ga-label="High-Frequency Ventilation / mortality">
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Search in PubMed
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ref="linksrc=search_in_mesh_link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=High-Frequency+Ventilation"
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data-ga-category="search_mesh"
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data-ga-action="mesh_term_link"
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data-ga-label="High-Frequency Ventilation / mortality">
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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ref="linksrc=add_to_search_link"
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role="button"
|
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data-search-term=""High-Frequency Ventilation/mortality"[MeSH]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""High-Frequency Ventilation/mortality"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword Hospital Mortality"
|
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tabindex="0"
|
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aria-controls="keyword-actions-mesh-terms-8"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Hospital Mortality
|
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</button><div id="keyword-actions-mesh-terms-8"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Hospital Mortality"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Hospital+Mortality%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Hospital+Mortality%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Hospital Mortality"[MeSH]"
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Search in PubMed
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ref="linksrc=search_in_mesh_link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Hospital+Mortality"
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data-ga-category="search_mesh"
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data-ga-action="mesh_term_link"
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data-ga-label="Hospital Mortality">
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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ref="linksrc=add_to_search_link"
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role="button"
|
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data-search-term=""Hospital Mortality"[MeSH]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""Hospital Mortality"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword Humans"
|
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tabindex="0"
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aria-controls="keyword-actions-mesh-terms-9"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Humans
|
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</button><div id="keyword-actions-mesh-terms-9"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Humans"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Humans"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Humans"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Humans"[MeSH]"
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data-ga-category="search"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword Infant"
|
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tabindex="0"
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|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Infant
|
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</button><div id="keyword-actions-mesh-terms-10"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Infant"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Infant%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Infant%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Infant"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Infant"
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Search in MeSH
|
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Infant"[MeSH]"
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data-ga-category="search"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Randomized Controlled Trials as Topic"
|
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tabindex="0"
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aria-controls="keyword-actions-mesh-terms-11"
|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Randomized Controlled Trials as Topic
|
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</button><div id="keyword-actions-mesh-terms-11"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Randomized Controlled Trials as Topic"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Randomized+Controlled+Trials+as+Topic%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Randomized+Controlled+Trials+as+Topic%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Randomized Controlled Trials as Topic"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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Search in MeSH
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