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{"id":13315,"date":"2024-05-23T12:27:02","date_gmt":"2024-05-23T16:27:02","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=13315"},"modified":"2024-05-23T12:27:02","modified_gmt":"2024-05-23T16:27:02","slug":"avian-influenza-a-h5n1-virus-sequences","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/23\/avian-influenza-a-h5n1-virus-sequences\/","title":{"rendered":"New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI"},"content":{"rendered":"<p>Sequence data from the <a href=\"https:\/\/www.cdc.gov\/flu\/avianflu\/mammals.htm\">ongoing avian influenza A (H5N1) virus outbreak in cattle<\/a> are now available through NLM\u2019s NCBI resources <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/labs\/virus\/vssi\/#\/virus?SeqType_s=Nucleotide&VirusLineage_ss=Alphainfluenzavirus,%20taxid:197911&Serotype_s=H5N1&CollectionDate_dr=2023-12-01T00:00:00.00Z%20TO%202024-05-16T23:59:59.00Z&Country_s=USA\">NCBI Virus<\/a> and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/genome\/?taxon=2955291&release_year=2023%3A2024&utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">NCBI Datasets<\/a>.<\/p>\n<p>These data were submitted by the <a href=\"https:\/\/www.usda.gov\/\">U.S. Department of Agriculture (USDA)<\/a>, <a href=\"https:\/\/www.cdc.gov\">U.S. Centers for Disease Control and Prevention (CDC)<\/a>, the <a href=\"https:\/\/www.who.int\/\">World Health Organization (WHO)<\/a>, <a href=\"https:\/\/www.iastate.edu\/\">Iowa State University<\/a>, and <a href=\"https:\/\/www.stjude.org\/\">St. Jude Children’s Research Hospital<\/a>.\u00a0 <!--more--><\/p>\n<h5>Access through NCBI Virus<\/h5>\n<p>You can access <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/genbank\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">GenBank<\/a> virus sequences, annotations, and metadata for all viruses in our archive, including Alphainfluenza virus, via <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/labs\/virus\/vssi\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523#\/\">NCBI Virus<\/a>. A variety of filters are available to select sequences that match your research interests, and many fields of metadata are normalized to make data comparisons easier. For example, the following set of filter terms will provide all H5N1 sequences from the U.S. from December 1, 2023, to May 16, 2024, which were isolated from human hosts (Figure 1). To search for sequences from specific sample types such as milk, use the isolation source filter.<\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"13319\" data-permalink=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/23\/avian-influenza-a-h5n1-virus-sequences\/virus-h5n1-texas-human\/\" data-orig-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?fit=1437%2C773&ssl=1\" data-orig-size=\"1437,773\" data-comments-opened=\"1\" data-image-meta=\"{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}\" data-image-title=\"Virus-H5N1-Texas-Human\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?fit=300%2C161&ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?fit=1024%2C551&ssl=1\" class=\"alignright size-full wp-image-13319\" src=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=1108%2C596&ssl=1\" alt=\"Screenshot of a table showing the H5N1 virus search results\" width=\"1108\" height=\"596\" srcset=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?w=1437&ssl=1 1437w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=300%2C161&ssl=1 300w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=1024%2C551&ssl=1 1024w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=150%2C81&ssl=1 150w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=768%2C413&ssl=1 768w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=1200%2C646&ssl=1 1200w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2024\/05\/Virus-H5N1-Texas-Human.png?resize=270%2C145&ssl=1 270w\" sizes=\"auto, (max-width: 1108px) 100vw, 1108px\" \/><span style=\"font-size: 17px;\"><em>Figure 1: NCBI Virus Influenza Data Hub browser filtered for <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/labs\/virus\/vssi\/#\/virus?SeqType_s=Nucleotide&VirusLineage_ss=Alphainfluenzavirus,%20taxid:197911&Serotype_s=H5N1&CollectionDate_dr=2023-12-01T00:00:00.00Z%20TO%202024-05-16T23:59:59.00Z&Country_s=USA&HostLineage_ss=Homo%20sapiens%20(human),%20taxid:9606\">H5N1 sequences collected between December 1, 2023, and May 16, 2024, in the USA that were isolated from human hosts<\/a>. Selected filters shown on the left-hand side of the image. The browser shows a much larger set of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/labs\/virus\/vssi\/#\/virus?SeqType_s=Nucleotide&VirusLineage_ss=Alphainfluenzavirus,%20taxid:197911&Serotype_s=H5N1&CollectionDate_dr=2023-12-01T00:00:00.00Z%20TO%202024-05-16T23:59:59.00Z&Country_s=USA&HostLineage_ss=Bos%20taurus%20(cattle),%20taxid:9913\">H5N1 sequences isolated from cattle<\/a>.<\/em><\/span><\/p>\n<p>Coming soon! We are working on providing influenza genomes consisting of a full set of segments grouped by sample metadata, and they will soon be available through NCBI Virus. Stay tuned for more information.<\/p>\n<h5>Need command-line access? Check out NCBI Datasets!<\/h5>\n<p>Access data programmatically with the NCBI Datasets <em>datasets<\/em> and <em>dataformat <\/em>command-line tools. Use genus name (<em>Alphainfluenzavirus<\/em>), taxid (197911) or NCBI Nucleotide accession. You can filter by date, host, and geographic location. See our <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/docs\/v2\/download-and-install\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">help documentation<\/a> on command-line access to get started. You can also refer to the Alphainfluenza virus documentation for further details:<\/p>\n<ul>\n<li><span style=\"font-size: 17px;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/docs\/v2\/how-tos\/virus\/influenza-metadata\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">Get Alphainfluenza virus genome metadata<\/a><\/span><\/li>\n<li><span style=\"font-size: 17px;\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/docs\/v2\/how-tos\/virus\/get-influenza-genomes\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">Download an Alphainfluenza genome data package<\/a><\/span><\/li>\n<\/ul>\n<h5>Do you have Influenza virus sequence data? Submit to NCBI!<\/h5>\n<p>You can submit your influenza virus sequence data reads to the <a href=\"https:\/\/submit.ncbi.nlm.nih.gov\/subs\/sra\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">Sequence Read Archive (SRA)<\/a> or assembled genome data to <a href=\"https:\/\/submit.ncbi.nlm.nih.gov\/subs\/genbank\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">GenBank<\/a> using the <a href=\"https:\/\/submit.ncbi.nlm.nih.gov\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=virus-influenza-20240523\">NCBI Submission Portal<\/a>. Influenza viruses have a dedicated submission process (no annotation file necessary), and submissions are typically processed within hours.<\/p>\n<p>If you plan to submit large volumes of sequences to GenBank and would prefer to submit using a command line option, please contact the GenBank Team by email at <a href=\"mailto:gb-admin@ncbi.nlm.nih.gov\">gb-admin@ncbi.nlm.nih.gov<\/a> for instructions on creating and submitting through an FTP account.<\/p>\n<p>If you have questions or concerns about submitting data to SRA, please contact our SRA Team by email at <a href=\"mailto:sra@ncbi.nlm.nih.gov\">sra@ncbi.nlm.nih.gov<\/a>.<\/p>\n<h5>Learn more<\/h5>\n<p>For more information on HN51 bird flu, <a href=\"https:\/\/www.cdc.gov\/flu\/avianflu\/mammals.htm#:~:text=Specifically%2C%20recent%20HPAI%20A(H5N1,%2C%20France%2C%20and%20other%20countries\">visit the CDC website<\/a>.<\/p>\n<h5>Stay up to date<\/h5>\n<p>Follow us on social media\u00a0<a href=\"https:\/\/twitter.com\/ncbi\">@NCBI<\/a>\u00a0and\u00a0<a href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_52\">join our mailing list<\/a>\u00a0to keep up to date with\u00a0GenBank\u00a0and other NCBI news.<\/p>\n<h5>Questions?<\/h5>\n<p>Please <a href=\"https:\/\/support.nlm.nih.gov\/support\/create-case\/\">reach out to us<\/a> with questions or feedback.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sequence data from the ongoing avian influenza A (H5N1) virus outbreak in cattle are now available through NLM\u2019s NCBI resources NCBI Virus and NCBI Datasets. These data were submitted by the U.S. Department of Agriculture (USDA), U.S. Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), Iowa State University, and St. Jude … <a href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/23\/avian-influenza-a-h5n1-virus-sequences\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI<\/span> <span class=\"meta-nav\">→<\/span><\/a><\/p>\n","protected":false},"author":42204617,"featured_media":13330,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[1201719,29189,693060836,693060764,651448],"table_tags":[],"class_list":["post-13315","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-genbank","tag-influenza","tag-ncbi-datasets","tag-ncbi-virus","tag-sra"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/23\/avian-influenza-a-h5n1-virus-sequences\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"Sequence data from the ongoing avian influenza A (H5N1) virus outbreak in cattle are now available through NLM\u2019s NCBI resources NCBI Virus and NCBI Datasets. These data were submitted by the U.S. Department of Agriculture (USDA), U.S. Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), Iowa State University, and St. Jude … Continue reading New Data Available! 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Access Avian Influenza A (H5N1) Virus Sequences at NCBI - NCBI Insights","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2024\/05\/23\/avian-influenza-a-h5n1-virus-sequences\/","og_locale":"en_US","og_type":"article","og_title":"New Data Available! Access Avian Influenza A (H5N1) Virus Sequences at NCBI - NCBI Insights","og_description":"Sequence data from the ongoing avian influenza A (H5N1) virus outbreak in cattle are now available through NLM\u2019s NCBI resources NCBI Virus and NCBI Datasets. These data were submitted by the U.S. Department of Agriculture (USDA), U.S. Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO), Iowa State University, and St. Jude … Continue reading New Data Available! 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