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<meta name="keywords" content="C4302356, neoplastic process, primary low grade serous adenocarcinoma of ovary, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="" /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=928025
|
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ConceptID=C4302356
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Primary low grade serous adenocarcinoma of ovary</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>928025</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4302356</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td><span class="bold">SNOMED CT: </span></td>
|
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<td>Primary low grade serous adenocarcinoma of ovary (722684000)</td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36734363">Stage, treatment and survival of low-grade serous ovarian carcinoma in the Netherlands: A nationwide study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">De Decker K,
|
||
Wenzel HHB,
|
||
Bart J,
|
||
van der Aa MA,
|
||
Kruitwagen RFPM,
|
||
Nijman HW,
|
||
Kruse AJ</span><br />
|
||
<span class="medgenPMjournal">Acta Obstet Gynecol Scand</span>
|
||
2023 Mar;102(3):246-256.
|
||
Epub 2023 Feb 3
|
||
doi: 10.1111/aogs.14518.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36734363" target="_blank">36734363</a><a href="/pmc/articles/PMC9951382" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36137845">Contemporary primary treatment of women with stage II-IV low-grade serous ovarian/peritoneal cancer (LGSOC): Determinants of relapse and disease-free survival.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gershenson DM,
|
||
Cobb LP,
|
||
Westin SN,
|
||
Zhang Y,
|
||
Jazaeri A,
|
||
Malpica A,
|
||
Sun CC</span><br />
|
||
<span class="medgenPMjournal">Gynecol Oncol</span>
|
||
2022 Nov;167(2):139-145.
|
||
Epub 2022 Sep 20
|
||
doi: 10.1016/j.ygyno.2022.09.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36137845" target="_blank">36137845</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33545690">Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Armstrong DK,
|
||
Alvarez RD,
|
||
Bakkum-Gamez JN,
|
||
Barroilhet L,
|
||
Behbakht K,
|
||
Berchuck A,
|
||
Chen LM,
|
||
Cristea M,
|
||
DeRosa M,
|
||
Eisenhauer EL,
|
||
Gershenson DM,
|
||
Gray HJ,
|
||
Grisham R,
|
||
Hakam A,
|
||
Jain A,
|
||
Karam A,
|
||
Konecny GE,
|
||
Leath CA,
|
||
Liu J,
|
||
Mahdi H,
|
||
Martin L,
|
||
Matei D,
|
||
McHale M,
|
||
McLean K,
|
||
Miller DS,
|
||
O'Malley DM,
|
||
Percac-Lima S,
|
||
Ratner E,
|
||
Remmenga SW,
|
||
Vargas R,
|
||
Werner TL,
|
||
Zsiros E,
|
||
Burns JL,
|
||
Engh AM</span><br />
|
||
<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
|
||
2021 Feb 2;19(2):191-226.
|
||
doi: 10.6004/jnccn.2021.0007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33545690" target="_blank">33545690</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(primary%20low%20grade%20serous%20adenocarcinoma%20of%20ovary)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36734363">Stage, treatment and survival of low-grade serous ovarian carcinoma in the Netherlands: A nationwide study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">De Decker K,
|
||
Wenzel HHB,
|
||
Bart J,
|
||
van der Aa MA,
|
||
Kruitwagen RFPM,
|
||
Nijman HW,
|
||
Kruse AJ</span><br />
|
||
<span class="medgenPMjournal">Acta Obstet Gynecol Scand</span>
|
||
2023 Mar;102(3):246-256.
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<div class="portlet_content ln"><span class="medgenPMauthor">Monk BJ,
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Marth C,
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<div class="nl"><a target="_blank" href="/pubmed/31969252">Low-grade serous ovarian cancer: State of the science.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Slomovitz B,
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Gourley C,
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Carey MS,
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Malpica A,
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Huntsman D,
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Fader AN,
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Schlumbrecht M,
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Sun CC,
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Ludemann J,
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Cooney GA,
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Coleman R,
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Sood AK,
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Mahdi H,
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Wong KK,
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Covens A,
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O'Malley DM,
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Lecuru F,
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Cobb LP,
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Caputo TA,
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May T,
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Huang M,
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Siemon J,
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Fernández ML,
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Ray-Coquard I,
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<div class="nl"><a target="_blank" href="/pubmed/31654691">Ovarian tumors: a survey of selected advances of note during the life of this journal.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Young RH</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/31654691">Ovarian tumors: a survey of selected advances of note during the life of this journal.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/32822286">MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Monk BJ,
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Grisham RN,
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Banerjee S,
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Kalbacher E,
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Mirza MR,
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Coleman RL,
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Westermann A,
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Marth C,
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Sehouli J,
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O'Malley DM,
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Churruca C,
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Boyd AP,
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Kristensen G,
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Clamp A,
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Ray-Coquard I,
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Vergote I</span><br />
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<div class="nl"><a target="_blank" href="/pubmed/31969252">Low-grade serous ovarian cancer: State of the science.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Slomovitz B,
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Gourley C,
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Carey MS,
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Malpica A,
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Shih IM,
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Huntsman D,
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Fader AN,
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Grisham RN,
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Schlumbrecht M,
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Sun CC,
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Ludemann J,
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Cooney GA,
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Coleman R,
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Sood AK,
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Mahdi H,
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Wong KK,
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Covens A,
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O'Malley DM,
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Lecuru F,
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Cobb LP,
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Caputo TA,
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May T,
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Huang M,
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Siemon J,
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Fernández ML,
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Ray-Coquard I,
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Gershenson DM</span><br />
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<span class="medgenPMjournal">Gynecol Oncol</span>
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2020 Mar;156(3):715-725.
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Epub 2020 Jan 20
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doi: 10.1016/j.ygyno.2019.12.033.
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<span class="bold">PMID: </span><a href="/pubmed/31969252" target="_blank">31969252</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20low%20grade%20serous%20adenocarcinoma%20of%20ovary%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/32822286">MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Monk BJ,
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Grisham RN,
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Banerjee S,
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Kalbacher E,
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Mirza MR,
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Romero I,
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Vuylsteke P,
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Coleman RL,
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Hilpert F,
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Oza AM,
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Westermann A,
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Oehler MK,
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Pignata S,
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Aghajanian C,
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Colombo N,
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Drill E,
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Cibula D,
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Moore KN,
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Christy-Bittel J,
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Del Campo JM,
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Berger R,
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Marth C,
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Sehouli J,
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O'Malley DM,
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Churruca C,
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Boyd AP,
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Kristensen G,
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Clamp A,
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Ray-Coquard I,
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Vergote I</span><br />
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<span class="medgenPMjournal">J Clin Oncol</span>
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2020 Nov 10;38(32):3753-3762.
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Epub 2020 Aug 21
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doi: 10.1200/JCO.20.01164.
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<span class="bold">PMID: </span><a href="/pubmed/32822286" target="_blank">32822286</a><a href="/pmc/articles/PMC7655017" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31654691">Ovarian tumors: a survey of selected advances of note during the life of this journal.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Young RH</span><br />
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||
<span class="bold">PMID: </span><a href="/pubmed/28228232" target="_blank">28228232</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16100867">Serous and mucinous borderline (low malignant potential) tumors of the ovary.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Acs G</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Pathol</span>
|
||
2005 Jun;123 Suppl:S13-57.
|
||
doi: 10.1309/J6PXXK1HQJAEBVPM.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16100867" target="_blank">16100867</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20low%20grade%20serous%20adenocarcinoma%20of%20ovary%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (33)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36734363">Stage, treatment and survival of low-grade serous ovarian carcinoma in the Netherlands: A nationwide study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">De Decker K,
|
||
Wenzel HHB,
|
||
Bart J,
|
||
van der Aa MA,
|
||
Kruitwagen RFPM,
|
||
Nijman HW,
|
||
Kruse AJ</span><br />
|
||
<span class="medgenPMjournal">Acta Obstet Gynecol Scand</span>
|
||
2023 Mar;102(3):246-256.
|
||
Epub 2023 Feb 3
|
||
doi: 10.1111/aogs.14518.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36734363" target="_blank">36734363</a><a href="/pmc/articles/PMC9951382" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35238033">Genomic catastrophe, the peritoneal cavity and ovarian cancer prevention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yoon JY,
|
||
Chapel DB,
|
||
Goebel E,
|
||
Qian X,
|
||
Mito JK,
|
||
Horowitz NS,
|
||
Miron A,
|
||
Soong TR,
|
||
Xian W,
|
||
Crum CP</span><br />
|
||
<span class="medgenPMjournal">J Pathol</span>
|
||
2022 Jul;257(3):255-261.
|
||
Epub 2022 Apr 18
|
||
doi: 10.1002/path.5891.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35238033" target="_blank">35238033</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32822286">MILO/ENGOT-ov11: Binimetinib Versus Physician's Choice Chemotherapy in Recurrent or Persistent Low-Grade Serous Carcinomas of the Ovary, Fallopian Tube, or Primary Peritoneum.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Monk BJ,
|
||
Grisham RN,
|
||
Banerjee S,
|
||
Kalbacher E,
|
||
Mirza MR,
|
||
Romero I,
|
||
Vuylsteke P,
|
||
Coleman RL,
|
||
Hilpert F,
|
||
Oza AM,
|
||
Westermann A,
|
||
Oehler MK,
|
||
Pignata S,
|
||
Aghajanian C,
|
||
Colombo N,
|
||
Drill E,
|
||
Cibula D,
|
||
Moore KN,
|
||
Christy-Bittel J,
|
||
Del Campo JM,
|
||
Berger R,
|
||
Marth C,
|
||
Sehouli J,
|
||
O'Malley DM,
|
||
Churruca C,
|
||
Boyd AP,
|
||
Kristensen G,
|
||
Clamp A,
|
||
Ray-Coquard I,
|
||
Vergote I</span><br />
|
||
<span class="medgenPMjournal">J Clin Oncol</span>
|
||
2020 Nov 10;38(32):3753-3762.
|
||
Epub 2020 Aug 21
|
||
doi: 10.1200/JCO.20.01164.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32822286" target="_blank">32822286</a><a href="/pmc/articles/PMC7655017" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31654691">Ovarian tumors: a survey of selected advances of note during the life of this journal.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Young RH</span><br />
|
||
<span class="medgenPMjournal">Hum Pathol</span>
|
||
2020 Jan;95:169-206.
|
||
Epub 2019 Oct 22
|
||
doi: 10.1016/j.humpath.2019.09.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31654691" target="_blank">31654691</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28228232">Hormone receptor expression profile of low-grade serous ovarian cancers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Buttarelli M,
|
||
Mascilini F,
|
||
Zannoni GF,
|
||
Ciucci A,
|
||
Martinelli E,
|
||
Filippetti F,
|
||
Scambia G,
|
||
Ferrandina G,
|
||
Gallo D</span><br />
|
||
<span class="medgenPMjournal">Gynecol Oncol</span>
|
||
2017 May;145(2):352-360.
|
||
Epub 2017 Feb 20
|
||
doi: 10.1016/j.ygyno.2017.02.029.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28228232" target="_blank">28228232</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Primary%20low%20grade%20serous%20adenocarcinoma%20of%20ovary%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23)</a></div></div>
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