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<!--
UID=892289
ConceptID=C4023679
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Abnormal circulating protein concentration</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>892289</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4023679</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Abnormal circulating protein level; Abnormality of circulating protein level; Blood protein disease; Serum protein abnormality</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0010876">HP:0010876</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">An abnormal level of a circulating protein in the blood. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Abnormal circulating protein concentration</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="matched_ds">Abnormal circulating protein concentration</span><ul><li><span class="TLline"><a href="/medgen/868636" ref="tree=MeSH" title="MedGen record for Abnormal circulating albumin concentration">Abnormal circulating albumin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/490153" ref="tree=MeSH" title="MedGen record for Hyperalbuminemia">Hyperalbuminemia</a></span></li><li><span class="TLline"><a href="/medgen/68694" ref="tree=MeSH" title="MedGen record for Hypoalbuminemia">Hypoalbuminemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1841543" ref="tree=MeSH" title="MedGen record for Abnormal circulating alpha-fetoprotein concentration">Abnormal circulating alpha-fetoprotein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1841521" ref="tree=MeSH" title="MedGen record for Decreased circulating alpha-fetoprotein concentration">Decreased circulating alpha-fetoprotein concentration</a></span></li><li><span class="TLline"><a href="/medgen/65916" ref="tree=MeSH" title="MedGen record for Elevated circulating alpha-fetoprotein concentration">Elevated circulating alpha-fetoprotein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/333423" ref="tree=MeSH" title="MedGen record for Elevated amniotic fluid alpha-fetoprotein">Elevated amniotic fluid alpha-fetoprotein</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1687192" ref="tree=MeSH" title="MedGen record for Abnormal circulating amylase concentration">Abnormal circulating amylase concentration</a></span><ul><li><span class="TLline"><a href="/medgen/105401" ref="tree=MeSH" title="MedGen record for Hyperamylasemia">Hyperamylasemia</a></span></li><li><span class="TLline"><a href="/medgen/1685636" ref="tree=MeSH" title="MedGen record for Hypoamylasemia">Hypoamylasemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1369272" ref="tree=MeSH" title="MedGen record for Abnormal circulating apolipoprotein concentration">Abnormal circulating apolipoprotein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1788103" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein concentration">Decreased circulating apolipoprotein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1634454" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein A-I concentration">Decreased circulating apolipoprotein A-I concentration</a></span></li><li><span class="TLline"><a href="/medgen/1842105" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein A-II concentration">Decreased circulating apolipoprotein A-II concentration</a></span></li><li><span class="TLline"><a href="/medgen/1814242" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein B concentration">Decreased circulating apolipoprotein B concentration</a></span></li><li><span class="TLline"><a href="/medgen/395336" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein C-II concentration">Decreased circulating apolipoprotein C-II concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841592" ref="tree=MeSH" title="MedGen record for Decreased circulating apolipoprotein E concentration">Decreased circulating apolipoprotein E concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1864026" ref="tree=MeSH" title="MedGen record for Elevated circulating lipoprotein X concentration">Elevated circulating lipoprotein X concentration</a></span></li><li><span class="TLline"><a href="/medgen/1786792" ref="tree=MeSH" title="MedGen record for Increased circulating apolipoprotein circulation">Increased circulating apolipoprotein circulation</a></span><ul><li><span class="TLline"><a href="/medgen/1638249" ref="tree=MeSH" title="MedGen record for Elevated circulating apolipoprotein A-II concentration">Elevated circulating apolipoprotein A-II concentration</a></span></li><li><span class="TLline"><a href="/medgen/1370981" ref="tree=MeSH" title="MedGen record for Elevated circulating apolipoprotein A-IV concentration">Elevated circulating apolipoprotein A-IV concentration</a></span></li><li><span class="TLline"><a href="/medgen/1632943" ref="tree=MeSH" title="MedGen record for Elevated circulating apolipoprotein B concentration">Elevated circulating apolipoprotein B concentration</a></span></li><li><span class="TLline"><a href="/medgen/1762678" ref="tree=MeSH" title="MedGen record for Elevated circulating apolipoprotein C-III concentration">Elevated circulating apolipoprotein C-III concentration</a></span></li><li><span class="TLline"><a href="/medgen/1842087" ref="tree=MeSH" title="MedGen record for Elevated circulating apolipoprotein E concentration">Elevated circulating apolipoprotein E concentration</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1863990" ref="tree=MeSH" title="MedGen record for Abnormal circulating atrial natriuretic peptide pro-hormone concentration">Abnormal circulating atrial natriuretic peptide pro-hormone concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1696996" ref="tree=MeSH" title="MedGen record for Abnormal circulating A-type atrial natriuretic peptide concentration">Abnormal circulating A-type atrial natriuretic peptide concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1699151" ref="tree=MeSH" title="MedGen record for Decreased circulating A-type natriuretic peptide concentration">Decreased circulating A-type natriuretic peptide concentration</a></span></li><li><span class="TLline"><a href="/medgen/1694271" ref="tree=MeSH" title="MedGen record for Increased circulating A-type natriuretic peptide concentration">Increased circulating A-type natriuretic peptide concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1389340" ref="tree=MeSH" title="MedGen record for Abnormal circulating B-type natriuretic peptide concentration">Abnormal circulating B-type natriuretic peptide concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1779799" ref="tree=MeSH" title="MedGen record for Increased circulating brain natriuretic peptide concentration">Increased circulating brain natriuretic peptide concentration</a></span></li><li><span class="TLline"><a href="/medgen/1385064" ref="tree=MeSH" title="MedGen record for Increased circulating NT-proBNP concentration">Increased circulating NT-proBNP concentration</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1623048" ref="tree=MeSH" title="MedGen record for Abnormal circulating beta-C-terminal telopeptide concentration">Abnormal circulating beta-C-terminal telopeptide concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1617405" ref="tree=MeSH" title="MedGen record for Decreased circulating beta-C-terminal telopeptide concentration">Decreased circulating beta-C-terminal telopeptide concentration</a></span></li><li><span class="TLline"><a href="/medgen/1614490" ref="tree=MeSH" title="MedGen record for Increased circulating beta-C-terminal telopeptide concentration">Increased circulating beta-C-terminal telopeptide concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/898382" ref="tree=MeSH" title="MedGen record for Abnormal circulating C-peptide concentration">Abnormal circulating C-peptide concentration</a></span><ul><li><span class="TLline"><a href="/medgen/894029" ref="tree=MeSH" title="MedGen record for Increased C-peptide level">Increased C-peptide level</a></span></li><li><span class="TLline"><a href="/medgen/909412" ref="tree=MeSH" title="MedGen record for Reduced C-peptide level">Reduced C-peptide level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1686782" ref="tree=MeSH" title="MedGen record for Abnormal circulating C-reactive protein concentration">Abnormal circulating C-reactive protein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1704066" ref="tree=MeSH" title="MedGen record for Reduced circulating C-reactive protein concecntration">Reduced circulating C-reactive protein concecntration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1726009" ref="tree=MeSH" title="MedGen record for Abnormal circulating ceruloplasmin concentration">Abnormal circulating ceruloplasmin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/472980" ref="tree=MeSH" title="MedGen record for Decreased circulating ceruloplasmin concentration">Decreased circulating ceruloplasmin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1750791" ref="tree=MeSH" title="MedGen record for Increased circulating ceruloplasmin concentration">Increased circulating ceruloplasmin concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1785637" ref="tree=MeSH" title="MedGen record for Abnormal circulating complement factor H related protein 1 concentration">Abnormal circulating complement factor H related protein 1 concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1783914" ref="tree=MeSH" title="MedGen record for Increased circulating complement factor H related protein 1 concentration">Increased circulating complement factor H related protein 1 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1788611" ref="tree=MeSH" title="MedGen record for Reduced circulating complement factor H related protein 1 concentration">Reduced circulating complement factor H related protein 1 concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/869169" ref="tree=MeSH" title="MedGen record for Abnormal circulating enzyme concentration">Abnormal circulating enzyme concentration</a></span><ul><li><span class="TLline"><a href="/medgen/868058" ref="tree=MeSH" title="MedGen record for Abnormal circulating creatine kinase concentration">Abnormal circulating creatine kinase concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1813078" ref="tree=MeSH" title="MedGen record for Decreased circulating creatine kinase concentration">Decreased circulating creatine kinase concentration</a></span></li><li><span class="TLline"><a href="/medgen/69128" ref="tree=MeSH" title="MedGen record for Elevated circulating creatine kinase concentration">Elevated circulating creatine kinase concentration</a></span></li><li><span class="TLline"><a href="/medgen/1696135" ref="tree=MeSH" title="MedGen record for Increased circulating creatine kinase BB isoform">Increased circulating creatine kinase BB isoform</a></span></li><li><span class="TLline"><a href="/medgen/1690106" ref="tree=MeSH" title="MedGen record for Increased circulating creatine kinase MB isoform">Increased circulating creatine kinase MB isoform</a></span></li><li><span class="TLline"><a href="/medgen/1707383" ref="tree=MeSH" title="MedGen record for Increased circulating creatine kinase MM isoform">Increased circulating creatine kinase MM isoform</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1863969" ref="tree=MeSH" title="MedGen record for Elevated circulating Angiotensin-converting enzyme concentration">Elevated circulating Angiotensin-converting enzyme concentration</a></span></li><li><span class="TLline"><a href="/medgen/435911" ref="tree=MeSH" title="MedGen record for Increased serum beta-hexosaminidase">Increased serum beta-hexosaminidase</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/808243" ref="tree=MeSH" title="MedGen record for Abnormal circulating ferritin concentration">Abnormal circulating ferritin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/66021" ref="tree=MeSH" title="MedGen record for Decreased circulating ferritin concentration">Decreased circulating ferritin concentration</a></span></li><li><span class="TLline"><a href="/medgen/69130" ref="tree=MeSH" title="MedGen record for Increased circulating ferritin concentration">Increased circulating ferritin concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1780919" ref="tree=MeSH" title="MedGen record for Abnormal circulating fetuin A concentration">Abnormal circulating fetuin A concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1785570" ref="tree=MeSH" title="MedGen record for Decreased circulating fetuin A concentration">Decreased circulating fetuin A concentration</a></span></li><li><span class="TLline"><a href="/medgen/1782731" ref="tree=MeSH" title="MedGen record for Increased circulating fetuin A concentration">Increased circulating fetuin A concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1692253" ref="tree=MeSH" title="MedGen record for Abnormal circulating globulin concentration">Abnormal circulating globulin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1392085" ref="tree=MeSH" title="MedGen record for Abnormal circulating beta globulin level">Abnormal circulating beta globulin level</a></span><ul><li><span class="TLline"><a href="/medgen/1615279" ref="tree=MeSH" title="MedGen record for Abnormal angiostatin level">Abnormal angiostatin level</a></span></li><li><span class="TLline"><a href="/medgen/1626189" ref="tree=MeSH" title="MedGen record for Abnormal circulating properdin level">Abnormal circulating properdin level</a></span></li><li><span class="TLline"><a href="/medgen/1694121" ref="tree=MeSH" title="MedGen record for Abnormal circulating transferrin concentration">Abnormal circulating transferrin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1613168" ref="tree=MeSH" title="MedGen record for Abnormal sex hormone-binding globulin level">Abnormal sex hormone-binding globulin level</a></span></li><li><span class="TLline"><a href="/medgen/1369502" ref="tree=MeSH" title="MedGen record for Abnormality of circulating beta-2-microglobulin level">Abnormality of circulating beta-2-microglobulin level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1691512" ref="tree=MeSH" title="MedGen record for Decreased circulating globulin level">Decreased circulating globulin level</a></span><ul><li><span class="TLline"><a href="/medgen/900318" ref="tree=MeSH" title="MedGen record for Decreased level of plasminogen">Decreased level of plasminogen</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1686812" ref="tree=MeSH" title="MedGen record for Increased circulating globulin level">Increased circulating globulin level</a></span><ul><li><span class="TLline"><a href="/medgen/257902" ref="tree=MeSH" title="MedGen record for Increased alpha-globulin">Increased alpha-globulin</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1644803" ref="tree=MeSH" title="MedGen record for Abnormal circulating glucose-6-phosphate dehydrogenase concentration">Abnormal circulating glucose-6-phosphate dehydrogenase concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1637526" ref="tree=MeSH" title="MedGen record for Abnormal glucose-6-phosphate dehydrogenase level in blood">Abnormal glucose-6-phosphate dehydrogenase level in blood</a></span><ul><li><span class="TLline"><a href="/medgen/1640558" ref="tree=MeSH" title="MedGen record for Decreased glucose-6-phosphate dehydrogenase level in blood">Decreased glucose-6-phosphate dehydrogenase level in blood</a></span></li><li><span class="TLline"><a href="/medgen/1645761" ref="tree=MeSH" title="MedGen record for Increased glucose-6-phosphate dehydrogenase level in blood">Increased glucose-6-phosphate dehydrogenase level in blood</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1636793" ref="tree=MeSH" title="MedGen record for Abnormal glucose-6-phosphate dehydrogenase level in dried blood spot">Abnormal glucose-6-phosphate dehydrogenase level in dried blood spot</a></span><ul><li><span class="TLline"><a href="/medgen/1640796" ref="tree=MeSH" title="MedGen record for Decreased glucose-6-phosphate dehydrogenase level in dried blood spot">Decreased glucose-6-phosphate dehydrogenase level in dried blood spot</a></span></li><li><span class="TLline"><a href="/medgen/1641574" ref="tree=MeSH" title="MedGen record for Increased glucose-6-phosphate dehydrogenase level in dried blood spot">Increased glucose-6-phosphate dehydrogenase level in dried blood spot</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1632528" ref="tree=MeSH" title="MedGen record for Abnormal glucose-6-phosphate dehydrogenase level in leukocytes">Abnormal glucose-6-phosphate dehydrogenase level in leukocytes</a></span><ul><li><span class="TLline"><a href="/medgen/1636963" ref="tree=MeSH" title="MedGen record for Decreased glucose-6-phosphate dehydrogenase level in leukocytes">Decreased glucose-6-phosphate dehydrogenase level in leukocytes</a></span></li><li><span class="TLline"><a href="/medgen/1638267" ref="tree=MeSH" title="MedGen record for Increased glucose-6-phosphate dehydrogenase level in leukocytes">Increased glucose-6-phosphate dehydrogenase level in leukocytes</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1643932" ref="tree=MeSH" title="MedGen record for Abnormal glucose-6-phosphate dehydrogenase level in red blood cells">Abnormal glucose-6-phosphate dehydrogenase level in red blood cells</a></span><ul><li><span class="TLline"><a href="/medgen/1634509" ref="tree=MeSH" title="MedGen record for Decreased glucose-6-phosphate dehydrogenase level in red blood cells">Decreased glucose-6-phosphate dehydrogenase level in red blood cells</a></span></li><li><span class="TLline"><a href="/medgen/1637238" ref="tree=MeSH" title="MedGen record for Increased glucose-6-phosphate dehydrogenase level in red blood cells">Increased glucose-6-phosphate dehydrogenase level in red blood cells</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1641774" ref="tree=MeSH" title="MedGen record for Abnormal glucose-6-phosphate dehydrogenase level in tissue">Abnormal glucose-6-phosphate dehydrogenase level in tissue</a></span><ul><li><span class="TLline"><a href="/medgen/1633293" ref="tree=MeSH" title="MedGen record for Decreased glucose-6-phosphate dehydrogenase level in tissue">Decreased glucose-6-phosphate dehydrogenase level in tissue</a></span></li><li><span class="TLline"><a href="/medgen/1645021" ref="tree=MeSH" title="MedGen record for Increased glucose-6-phosphate dehydrogenase level in tissue">Increased glucose-6-phosphate dehydrogenase level in tissue</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1707291" ref="tree=MeSH" title="MedGen record for Abnormal circulating haptoglobin concentration">Abnormal circulating haptoglobin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1698119" ref="tree=MeSH" title="MedGen record for Elevated haptoglobin level">Elevated haptoglobin level</a></span></li><li><span class="TLline"><a href="/medgen/1686017" ref="tree=MeSH" title="MedGen record for Reduced haptoglobin level">Reduced haptoglobin level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1634914" ref="tree=MeSH" title="MedGen record for Abnormal circulating hepcidin concentration">Abnormal circulating hepcidin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1643751" ref="tree=MeSH" title="MedGen record for Decreased circulating hepcidin concentration">Decreased circulating hepcidin concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1841555" ref="tree=MeSH" title="MedGen record for Abnormal circulating mannose-binding protein concentration">Abnormal circulating mannose-binding protein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1691135" ref="tree=MeSH" title="MedGen record for Decreased circulating mannose-binding protein concentration">Decreased circulating mannose-binding protein concentration</a></span></li><li><span class="TLline"><a href="/medgen/1706367" ref="tree=MeSH" title="MedGen record for Increased circulating mannose-binding protein concentration">Increased circulating mannose-binding protein concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1841810" ref="tree=MeSH" title="MedGen record for Abnormal circulating membrane cofactor protein concentration">Abnormal circulating membrane cofactor protein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1841661" ref="tree=MeSH" title="MedGen record for Decreased circulating membrane cofactor protein concentration">Decreased circulating membrane cofactor protein concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841825" ref="tree=MeSH" title="MedGen record for Elevated circulating membrane cofactor protein concentration">Elevated circulating membrane cofactor protein concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1788192" ref="tree=MeSH" title="MedGen record for Abnormal circulating prealbumin concentration">Abnormal circulating prealbumin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1375131" ref="tree=MeSH" title="MedGen record for Decreased circulating prealbumin concentration">Decreased circulating prealbumin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1778311" ref="tree=MeSH" title="MedGen record for Increased circulating prealbumin concentration">Increased circulating prealbumin concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1384239" ref="tree=MeSH" title="MedGen record for Abnormal circulating thyroglobulin concentration">Abnormal circulating thyroglobulin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1864126" ref="tree=MeSH" title="MedGen record for Decreased circulating thyroglobulin concentration">Decreased circulating thyroglobulin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1375023" ref="tree=MeSH" title="MedGen record for Increased circulating thyroglobulin concentration">Increased circulating thyroglobulin concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1841918" ref="tree=MeSH" title="MedGen record for Abnormal circulating thyroxine-binding globulin concentration">Abnormal circulating thyroxine-binding globulin concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1841890" ref="tree=MeSH" title="MedGen record for Decreased circulating thyroxine-binding globulin concentration">Decreased circulating thyroxine-binding globulin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1613486" ref="tree=MeSH" title="MedGen record for Increased circulating thyroxine-binding globulin level">Increased circulating thyroxine-binding globulin level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1712733" ref="tree=MeSH" title="MedGen record for Abnormal cystatin C level">Abnormal cystatin C level</a></span><ul><li><span class="TLline"><a href="/medgen/1715248" ref="tree=MeSH" title="MedGen record for Decreased cystatin C level">Decreased cystatin C level</a></span></li><li><span class="TLline"><a href="/medgen/1709975" ref="tree=MeSH" title="MedGen record for Increased cystatin C level">Increased cystatin C level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1390394" ref="tree=MeSH" title="MedGen record for Abnormal insulin like growth factor binding protein acid labile subunit level">Abnormal insulin like growth factor binding protein acid labile subunit level</a></span><ul><li><span class="TLline"><a href="/medgen/1814347" ref="tree=MeSH" title="MedGen record for Increased insulin like growth factor binding protein acid labile subunit concentration">Increased insulin like growth factor binding protein acid labile subunit concentration</a></span></li><li><span class="TLline"><a href="/medgen/1390100" ref="tree=MeSH" title="MedGen record for Reduced insulin like growth factor binding protein acid labile subunit concentration">Reduced insulin like growth factor binding protein acid labile subunit concentration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1387105" ref="tree=MeSH" title="MedGen record for Abnormal retinol-binding protein level">Abnormal retinol-binding protein level</a></span><ul><li><span class="TLline"><a href="/medgen/1388725" ref="tree=MeSH" title="MedGen record for Decreased retinol-binding protein level">Decreased retinol-binding protein level</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/870724" ref="tree=MeSH" title="MedGen record for Abnormality of the kinin-kallikrein system">Abnormality of the kinin-kallikrein system</a></span></li><li><span class="TLline"><a href="/medgen/1864269" ref="tree=MeSH" title="MedGen record for Decreased circulating ficolin 3 concentration">Decreased circulating ficolin 3 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1053359" ref="tree=MeSH" title="MedGen record for Decreased circulating transcobalamin I concentration">Decreased circulating transcobalamin I concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841932" ref="tree=MeSH" title="MedGen record for Decreased circulating transcobalamin II concentration">Decreased circulating transcobalamin II concentration</a></span></li><li><span class="TLline"><a href="/medgen/168057" ref="tree=MeSH" title="MedGen record for Deficiency of ferroxidase">Deficiency of ferroxidase</a></span></li><li><span class="TLline"><a href="/medgen/1054053" ref="tree=MeSH" title="MedGen record for Diminished circulating cationic trypsinogen concentration">Diminished circulating cationic trypsinogen concentration</a></span></li><li><span class="TLline"><a href="/medgen/1373345" ref="tree=MeSH" title="MedGen record for Elevated carcinoma antigen 125 level">Elevated carcinoma antigen 125 level</a></span></li><li><span class="TLline"><a href="/medgen/1864097" ref="tree=MeSH" title="MedGen record for Elevated circulating beta chorionic gonadotropin concentration">Elevated circulating beta chorionic gonadotropin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1841653" ref="tree=MeSH" title="MedGen record for Elevated circulating CA19-9 concentration">Elevated circulating CA19-9 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1863535" ref="tree=MeSH" title="MedGen record for Elevated circulating calprotectin concentration">Elevated circulating calprotectin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1378758" ref="tree=MeSH" title="MedGen record for Elevated circulating carcinoembryonic antigen concentration">Elevated circulating carcinoembryonic antigen concentration</a></span></li><li><span class="TLline"><a href="/medgen/1787173" ref="tree=MeSH" title="MedGen record for Elevated circulating cartilage oligomeric matrix protein concentration">Elevated circulating cartilage oligomeric matrix protein concentration</a></span></li><li><span class="TLline"><a href="/medgen/1716604" ref="tree=MeSH" title="MedGen record for Elevated circulating CCL18 level">Elevated circulating CCL18 level</a></span></li><li><span class="TLline"><a href="/medgen/1747650" ref="tree=MeSH" title="MedGen record for Elevated circulating CHI3L1 level">Elevated circulating CHI3L1 level</a></span></li><li><span class="TLline"><a href="/medgen/1863642" ref="tree=MeSH" title="MedGen record for Elevated circulating DNAJB9 protein concentration">Elevated circulating DNAJB9 protein concentration</a></span></li><li><span class="TLline"><a href="/medgen/1696341" ref="tree=MeSH" title="MedGen record for Elevated circulating E selectin level">Elevated circulating E selectin level</a></span></li><li><span class="TLline"><a href="/medgen/1863579" ref="tree=MeSH" title="MedGen record for Elevated circulating granulocyte-macrophage colony-stimulating factor concentration">Elevated circulating granulocyte-macrophage colony-stimulating factor concentration</a></span></li><li><span class="TLline"><a href="/medgen/1787040" ref="tree=MeSH" title="MedGen record for Elevated circulating myoglobin concentration">Elevated circulating myoglobin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1775487" ref="tree=MeSH" title="MedGen record for Elevated circulating osteopontin level">Elevated circulating osteopontin level</a></span></li><li><span class="TLline"><a href="/medgen/1864358" ref="tree=MeSH" title="MedGen record for Elevated circulating soluble CD163 concentration">Elevated circulating soluble CD163 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1784407" ref="tree=MeSH" title="MedGen record for Elevated circulating soluble CD25 concentration">Elevated circulating soluble CD25 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1863971" ref="tree=MeSH" title="MedGen record for Elevated circulating soluble FASL concentration">Elevated circulating soluble FASL concentration</a></span></li><li><span class="TLline"><a href="/medgen/1773022" ref="tree=MeSH" title="MedGen record for Elevated circulating tenascin-C level">Elevated circulating tenascin-C level</a></span></li><li><span class="TLline"><a href="/medgen/1863999" ref="tree=MeSH" title="MedGen record for Elevated circulating type I procollagen aminoterminal propeptide concentration">Elevated circulating type I procollagen aminoterminal propeptide concentration</a></span></li><li><span class="TLline"><a href="/medgen/927605" ref="tree=MeSH" title="MedGen record for Elevated prostate-specific antigen level">Elevated prostate-specific antigen level</a></span></li><li><span class="TLline"><a href="/medgen/871164" ref="tree=MeSH" title="MedGen record for Hyperpepsinogenemia I">Hyperpepsinogenemia I</a></span></li><li><span class="TLline"><a href="/medgen/75648" ref="tree=MeSH" title="MedGen record for Hyperproteinemia">Hyperproteinemia</a></span></li><li><span class="TLline"><a href="/medgen/581229" ref="tree=MeSH" title="MedGen record for Hypoproteinemia">Hypoproteinemia</a></span><ul><li><span class="TLline"><a href="/medgen/870253" ref="tree=MeSH" title="MedGen record for Neonatal hypoproteinemia">Neonatal hypoproteinemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1687328" ref="tree=MeSH" title="MedGen record for Increased circulating galectin-3 level">Increased circulating galectin-3 level</a></span></li><li><span class="TLline"><a href="/medgen/1700584" ref="tree=MeSH" title="MedGen record for Increased circulating surfactant protein level">Increased circulating surfactant protein level</a></span></li><li><span class="TLline"><a href="/medgen/1677064" ref="tree=MeSH" title="MedGen record for Increased circulating trypsinogen">Increased circulating trypsinogen</a></span></li><li><span class="TLline"><a href="/medgen/1670949" ref="tree=MeSH" title="MedGen record for Reduced circulating alpha-1-antitrypsin concentration">Reduced circulating alpha-1-antitrypsin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1864050" ref="tree=MeSH" title="MedGen record for Reduced circulating cortisol-binding globulin concentration">Reduced circulating cortisol-binding globulin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1702486" ref="tree=MeSH" title="MedGen record for Reduced circulating fibronectin level">Reduced circulating fibronectin level</a></span></li><li><span class="TLline"><a href="/medgen/1841716" ref="tree=MeSH" title="MedGen record for Reduced circulating matrix metalloproteinase 2 concentration">Reduced circulating matrix metalloproteinase 2 concentration</a></span></li><li><span class="TLline"><a href="/medgen/1863552" ref="tree=MeSH" title="MedGen record for Reduced circulating NT-proANP concentration">Reduced circulating NT-proANP concentration</a></span></li><li><span class="TLline"><a href="/medgen/1815101" ref="tree=MeSH" title="MedGen record for Reduced circulating prekallikrein concentration">Reduced circulating prekallikrein concentration</a></span></li><li><span class="TLline"><a href="/medgen/1055170" ref="tree=MeSH" title="MedGen record for Reduced circulating progranulin concentration">Reduced circulating progranulin concentration</a></span></li><li><span class="TLline"><a href="/medgen/1864196" ref="tree=MeSH" title="MedGen record for Reduced circulating protein Z concentration">Reduced circulating protein Z concentration</a></span></li><li><span class="TLline"><a href="/medgen/1392848" ref="tree=MeSH" title="MedGen record for Reduced growth-hormone binding protein level">Reduced growth-hormone binding protein level</a></span></li><li><span class="TLline"><a href="/medgen/1382475" ref="tree=MeSH" title="MedGen record for Reduced insulin-like factor 3 level">Reduced insulin-like factor 3 level</a></span></li><li><span class="TLline"><a href="/medgen/1619390" ref="tree=MeSH" title="MedGen record for Reduced sex -hormone binding protein level">Reduced sex -hormone binding protein level</a></span></li><li><span class="TLline"><a href="/medgen/868478" ref="tree=MeSH" title="MedGen record for Reduced thyroxin-binding globulin">Reduced thyroxin-binding globulin</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/33313695">Biomarkers for Risk Assessment in Atrial Fibrillation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Berg DD,
Ruff CT,
Morrow DA</span><br />
<span class="medgenPMjournal">Clin Chem</span>
2021 Jan 8;67(1):87-95.
doi: 10.1093/clinchem/hvaa298.
<span class="bold">PMID: </span><a href="/pubmed/33313695" target="_blank">33313695</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27156756">Diagnosis and treatment of hyponatraemia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ball SG,
Iqbal Z</span><br />
<span class="medgenPMjournal">Best Pract Res Clin Endocrinol Metab</span>
2016 Mar;30(2):161-73.
Epub 2015 Dec 30
doi: 10.1016/j.beem.2015.12.001.
<span class="bold">PMID: </span><a href="/pubmed/27156756" target="_blank">27156756</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23633542">Principles of care for the diagnosis and treatment of von Willebrand disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Castaman G,
Goodeve A,
Eikenboom J;
European Group on von Willebrand Disease</span><br />
<span class="medgenPMjournal">Haematologica</span>
2013 May;98(5):667-74.
doi: 10.3324/haematol.2012.077263.
<span class="bold">PMID: </span><a href="/pubmed/23633542" target="_blank">23633542</a><a href="/pmc/articles/PMC3640108" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(abnormal%20circulating%20protein%20concentration)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (44)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37678743">Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Geng TT,
Chen JX,
Lu Q,
Wang PL,
Xia PF,
Zhu K,
Li Y,
Guo KQ,
Yang K,
Liao YF,
Zhou YF,
Liu G,
Pan A</span><br />
<span class="medgenPMjournal">Am J Kidney Dis</span>
2024 Jan;83(1):9-17.
Epub 2023 Sep 9
doi: 10.1053/j.ajkd.2023.05.014.
<span class="bold">PMID: </span><a href="/pubmed/37678743" target="_blank">37678743</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34736565">Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Palm J,
Holdenrieder S,
Hoffmann G,
Hörer J,
Shi R,
Klawonn F,
Ewert P</span><br />
<span class="medgenPMjournal">J Am Coll Cardiol</span>
2021 Nov 9;78(19):1890-1900.
doi: 10.1016/j.jacc.2021.08.056.
<span class="bold">PMID: </span><a href="/pubmed/34736565" target="_blank">34736565</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24037491">Natural Antibodies Against Sialoglycans.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shilova N,
Huflejt ME,
Vuskovic M,
Obukhova P,
Navakouski M,
Khasbiullina N,
Pazynina G,
Galanina O,
Bazhenov A,
Bovin N</span><br />
<span class="medgenPMjournal">Top Curr Chem</span>
2015;366:169-81.
doi: 10.1007/128_2013_469.
<span class="bold">PMID: </span><a href="/pubmed/24037491" target="_blank">24037491</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9272618">Mechanisms of hepatic chylomicron remnant clearance.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Willnow TE</span><br />
<span class="medgenPMjournal">Diabet Med</span>
1997 Aug;14 Suppl 3:S75-80.
doi: 10.1002/(sici)1096-9136(199708)14:3+&lt;s75::aid-dia449&gt;3.3.co;2-0.
<span class="bold">PMID: </span><a href="/pubmed/9272618" target="_blank">9272618</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8831910">Lipids, risk factors and ischaemic heart disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Castelli WP</span><br />
<span class="medgenPMjournal">Atherosclerosis</span>
1996 Jul;124 Suppl:S1-9.
doi: 10.1016/0021-9150(96)05851-0.
<span class="bold">PMID: </span><a href="/pubmed/8831910" target="_blank">8831910</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20protein%20concentration%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (845)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35115099">Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vaduganathan M,
Sattar N,
Xu J,
Butler J,
Mahaffey KW,
Neal B,
Shaw W,
Rosenthal N,
Pfeifer M,
Hansen MK,
Januzzi JL Jr</span><br />
<span class="medgenPMjournal">J Am Coll Cardiol</span>
2022 Feb 8;79(5):432-444.
doi: 10.1016/j.jacc.2021.11.027.
<span class="bold">PMID: </span><a href="/pubmed/35115099" target="_blank">35115099</a><a href="/pmc/articles/PMC8972403" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31421978">Wilson disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Guindi M</span><br />
<span class="medgenPMjournal">Semin Diagn Pathol</span>
2019 Nov;36(6):415-422.
Epub 2019 Jul 25
doi: 10.1053/j.semdp.2019.07.008.
<span class="bold">PMID: </span><a href="/pubmed/31421978" target="_blank">31421978</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28174093">New insights into thyroid hormone action.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mendoza A,
Hollenberg AN</span><br />
<span class="medgenPMjournal">Pharmacol Ther</span>
2017 May;173:135-145.
Epub 2017 Feb 4
doi: 10.1016/j.pharmthera.2017.02.012.
<span class="bold">PMID: </span><a href="/pubmed/28174093" target="_blank">28174093</a><a href="/pmc/articles/PMC5407910" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17952834">Contribution of triglyceride-rich lipoproteins to plasma free fatty acids.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Miles JM,
Nelson RH</span><br />
<span class="medgenPMjournal">Horm Metab Res</span>
2007 Oct;39(10):726-9.
doi: 10.1055/s-2007-990273.
<span class="bold">PMID: </span><a href="/pubmed/17952834" target="_blank">17952834</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1729049">Diabetes insipidus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blevins LS Jr,
Wand GS</span><br />
<span class="medgenPMjournal">Crit Care Med</span>
1992 Jan;20(1):69-79.
doi: 10.1097/00003246-199201000-00019.
<span class="bold">PMID: </span><a href="/pubmed/1729049" target="_blank">1729049</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20protein%20concentration%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (513)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/35115099">Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vaduganathan M,
Sattar N,
Xu J,
Butler J,
Mahaffey KW,
Neal B,
Shaw W,
Rosenthal N,
Pfeifer M,
Hansen MK,
Januzzi JL Jr</span><br />
<span class="medgenPMjournal">J Am Coll Cardiol</span>
2022 Feb 8;79(5):432-444.
doi: 10.1016/j.jacc.2021.11.027.
<span class="bold">PMID: </span><a href="/pubmed/35115099" target="_blank">35115099</a><a href="/pmc/articles/PMC8972403" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34671932">Factors influencing the levothyroxine dose in the hormone replacement therapy of primary hypothyroidism in adults.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Caron P,
Grunenwald S,
Persani L,
Borson-Chazot F,
Leroy R,
Duntas L</span><br />
<span class="medgenPMjournal">Rev Endocr Metab Disord</span>
2022 Jun;23(3):463-483.
Epub 2021 Oct 20
doi: 10.1007/s11154-021-09691-9.
<span class="bold">PMID: </span><a href="/pubmed/34671932" target="_blank">34671932</a><a href="/pmc/articles/PMC8528480" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31089732">Milk and Dairy Product Consumption and Inflammatory Biomarkers: An Updated Systematic Review of Randomized Clinical Trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ulven SM,
Holven KB,
Gil A,
Rangel-Huerta OD</span><br />
<span class="medgenPMjournal">Adv Nutr</span>
2019 May 1;10(suppl_2):S239-S250.
doi: 10.1093/advances/nmy072.
<span class="bold">PMID: </span><a href="/pubmed/31089732" target="_blank">31089732</a><a href="/pmc/articles/PMC6518147" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10830173">Obstructive nephropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Klahr S</span><br />
<span class="medgenPMjournal">Intern Med</span>
2000 May;39(5):355-61.
doi: 10.2169/internalmedicine.39.355.
<span class="bold">PMID: </span><a href="/pubmed/10830173" target="_blank">10830173</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6407376">Thyroid function in nonthyroidal illnesses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chopra IJ,
Hershman JM,
Pardridge WM,
Nicoloff JT</span><br />
<span class="medgenPMjournal">Ann Intern Med</span>
1983 Jun;98(6):946-57.
doi: 10.7326/0003-4819-98-6-946.
<span class="bold">PMID: </span><a href="/pubmed/6407376" target="_blank">6407376</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20protein%20concentration%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (449)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35115099">Stress Cardiac Biomarkers, Cardiovascular and Renal Outcomes, and Response to Canagliflozin.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vaduganathan M,
Sattar N,
Xu J,
Butler J,
Mahaffey KW,
Neal B,
Shaw W,
Rosenthal N,
Pfeifer M,
Hansen MK,
Januzzi JL Jr</span><br />
<span class="medgenPMjournal">J Am Coll Cardiol</span>
2022 Feb 8;79(5):432-444.
doi: 10.1016/j.jacc.2021.11.027.
<span class="bold">PMID: </span><a href="/pubmed/35115099" target="_blank">35115099</a><a href="/pmc/articles/PMC8972403" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33807271">High-Density Lipoproteins and the Kidney.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Strazzella A,
Ossoli A,
Calabresi L</span><br />
<span class="medgenPMjournal">Cells</span>
2021 Mar 31;10(4)
doi: 10.3390/cells10040764.
<span class="bold">PMID: </span><a href="/pubmed/33807271" target="_blank">33807271</a><a href="/pmc/articles/PMC8065870" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8931905">Metabolic effects of the menopause and oestrogen replacement.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stevenson JC</span><br />
<span class="medgenPMjournal">Baillieres Clin Obstet Gynaecol</span>
1996 Sep;10(3):449-67.
doi: 10.1016/s0950-3552(96)80025-3.
<span class="bold">PMID: </span><a href="/pubmed/8931905" target="_blank">8931905</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6407376">Thyroid function in nonthyroidal illnesses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chopra IJ,
Hershman JM,
Pardridge WM,
Nicoloff JT</span><br />
<span class="medgenPMjournal">Ann Intern Med</span>
1983 Jun;98(6):946-57.
doi: 10.7326/0003-4819-98-6-946.
<span class="bold">PMID: </span><a href="/pubmed/6407376" target="_blank">6407376</a></div>
<div class="nl"><a target="_blank" href="/pubmed/4646508">Alpha-fetoprotein in abortion.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seppälä M,
Ruoslahti E</span><br />
<span class="medgenPMjournal">Br Med J</span>
1972 Dec 30;4(5843):769-71.
doi: 10.1136/bmj.4.5843.769.
<span class="bold">PMID: </span><a href="/pubmed/4646508" target="_blank">4646508</a><a href="/pmc/articles/PMC1787034" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20protein%20concentration%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (336)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37678743">Nuclear Magnetic Resonance-Based Metabolomics and Risk of CKD.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Geng TT,
Chen JX,
Lu Q,
Wang PL,
Xia PF,
Zhu K,
Li Y,
Guo KQ,
Yang K,
Liao YF,
Zhou YF,
Liu G,
Pan A</span><br />
<span class="medgenPMjournal">Am J Kidney Dis</span>
2024 Jan;83(1):9-17.
Epub 2023 Sep 9
doi: 10.1053/j.ajkd.2023.05.014.
<span class="bold">PMID: </span><a href="/pubmed/37678743" target="_blank">37678743</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37672568">Calprotectin is a contributor to and potential therapeutic target for vascular calcification in chronic kidney disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amaya-Garrido A,
Brunet M,
Buffin-Meyer B,
Piedrafita A,
Grzesiak L,
Agbegbo E,
Del Bello A,
Ferrandiz I,
Ardeleanu S,
Bermudez-Lopez M,
Fedou C,
Camus M,
Burlet-Schiltz O,
Massines J,
Buléon M,
Feuillet G,
Alves M,
Neau E,
Casemayou A,
Breuil B,
Saulnier-Blache JS,
Denis C,
Voelkl J,
Glorieux G,
Hobson S,
Arefin S,
Rahman A,
Kublickiene K,
Stenvinkel P,
Bascands JL,
Faguer S,
Valdivielso JM,
Schanstra JP,
Klein J</span><br />
<span class="medgenPMjournal">Sci Transl Med</span>
2023 Sep 6;15(712):eabn5939.
doi: 10.1126/scitranslmed.abn5939.
<span class="bold">PMID: </span><a href="/pubmed/37672568" target="_blank">37672568</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34218252">Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Q,
Wu J,
Zhang X,
Li X,
Wu X,
Zhao Y,
Ren J</span><br />
<span class="medgenPMjournal">Cell Death Dis</span>
2021 Jul 3;12(7):673.
doi: 10.1038/s41419-021-03961-9.
<span class="bold">PMID: </span><a href="/pubmed/34218252" target="_blank">34218252</a><a href="/pmc/articles/PMC8254453" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9255228">The spectrum of growth-hormone insensitivity.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Parks JS,
Brown MR,
Faase ME</span><br />
<span class="medgenPMjournal">J Pediatr</span>
1997 Jul;131(1 Pt 2):S45-50.
doi: 10.1016/s0022-3476(97)70011-8.
<span class="bold">PMID: </span><a href="/pubmed/9255228" target="_blank">9255228</a></div>
<div class="nl"><a target="_blank" href="/pubmed/4646508">Alpha-fetoprotein in abortion.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seppälä M,
Ruoslahti E</span><br />
<span class="medgenPMjournal">Br Med J</span>
1972 Dec 30;4(5843):769-71.
doi: 10.1136/bmj.4.5843.769.
<span class="bold">PMID: </span><a href="/pubmed/4646508" target="_blank">4646508</a><a href="/pmc/articles/PMC1787034" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Abnormal%20circulating%20protein%20concentration%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (600)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/37984118">Circulating levels of inflammatory biomarkers in Huntington's disease: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Soltani Khaboushan A,
Moeinafshar A,
Ersi MH,
Teixeira AL,
Majidi Zolbin M,
Kajbafzadeh AM</span><br />
<span class="medgenPMjournal">J Neuroimmunol</span>
2023 Dec 15;385:578243.
Epub 2023 Nov 13
doi: 10.1016/j.jneuroim.2023.578243.
<span class="bold">PMID: </span><a href="/pubmed/37984118" target="_blank">37984118</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32805393">Alcohol use disorder and circulating cytokines: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Adams C,
Conigrave JH,
Lewohl J,
Haber P,
Morley KC</span><br />
<span class="medgenPMjournal">Brain Behav Immun</span>
2020 Oct;89:501-512.
Epub 2020 Aug 14
doi: 10.1016/j.bbi.2020.08.002.
<span class="bold">PMID: </span><a href="/pubmed/32805393" target="_blank">32805393</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ulven SM,
Holven KB,
Gil A,
Rangel-Huerta OD</span><br />
<span class="medgenPMjournal">Adv Nutr</span>
2019 May 1;10(suppl_2):S239-S250.
doi: 10.1093/advances/nmy072.
<span class="bold">PMID: </span><a href="/pubmed/31089732" target="_blank">31089732</a><a href="/pmc/articles/PMC6518147" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29557064">The Role of Endothelin in the Pathophysiology of Migraine-a Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Iljazi A,
Ayata C,
Ashina M,
Hougaard A</span><br />
<span class="medgenPMjournal">Curr Pain Headache Rep</span>
2018 Mar 19;22(4):27.
doi: 10.1007/s11916-018-0682-8.
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<div class="nl"><a target="_blank" href="/pubmed/26148446">Chronic fatigue syndrome and circulating cytokines: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blundell S,
Ray KK,
Buckland M,
White PD</span><br />
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2015 Nov;50:186-195.
Epub 2015 Jul 3
doi: 10.1016/j.bbi.2015.07.004.
<span class="bold">PMID: </span><a href="/pubmed/26148446" target="_blank">26148446</a></div>
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