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<meta name="keywords" content="C3642344, breast carcinoma by gene expression profile, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A header term that includes the following breast carcinoma subtypes determined by gene expression profiling: luminal A breast carcinoma, luminal B breast carcinoma, HER2 positive breast carcinoma, basal-like breast carcinoma, triple-negative breast carcinoma, and normal breast-like subtype of breast carcinoma." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=770984
ConceptID=C3642344
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Breast carcinoma by gene expression profile</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>770984</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3642344</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Breast Carcinoma by Gene Expression Profile; breast carcinoma by gene expression profile</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0006116" target="_blank">MONDO:0006116</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A header term that includes the following breast carcinoma subtypes determined by gene expression profiling: luminal A breast carcinoma, luminal B breast carcinoma, HER2 positive breast carcinoma, basal-like breast carcinoma, triple-negative breast carcinoma, and normal breast-like subtype of breast carcinoma. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Breast carcinoma by gene expression profile</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/122" ref="tree=MeSH" title="MedGen record for Adenocarcinoma">Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/167809" ref="tree=MeSH" title="MedGen record for Breast adenocarcinoma">Breast adenocarcinoma</a></span><ul><li><span class="matched_ds">Breast carcinoma by gene expression profile</span><ul><li><span class="TLline"><a href="/medgen/770987" ref="tree=MeSH" title="MedGen record for Basal-like breast carcinoma">Basal-like breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/743175" ref="tree=MeSH" title="MedGen record for HER2 positive breast carcinoma">HER2 positive breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793161" ref="tree=MeSH" title="MedGen record for Metastatic HER2-Positive Breast Carcinoma">Metastatic HER2-Positive Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793162" ref="tree=MeSH" title="MedGen record for Advanced HER2-Positive Breast Carcinoma">Advanced HER2-Positive Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793709" ref="tree=MeSH" title="MedGen record for Locally Advanced HER2-Positive Breast Carcinoma">Locally Advanced HER2-Positive Breast Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/770985" ref="tree=MeSH" title="MedGen record for Luminal A breast carcinoma">Luminal A breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/770986" ref="tree=MeSH" title="MedGen record for Luminal B breast carcinoma">Luminal B breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/771111" ref="tree=MeSH" title="MedGen record for Normal breast-like subtype of breast carcinoma">Normal breast-like subtype of breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1649548" ref="tree=MeSH" title="MedGen record for Triple-negative breast carcinoma">Triple-negative breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793278" ref="tree=MeSH" title="MedGen record for Early Stage Triple-Negative Breast Carcinoma">Early Stage Triple-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1654154" ref="tree=MeSH" title="MedGen record for Metastatic Triple-Negative Breast Carcinoma">Metastatic Triple-Negative Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1784796" ref="tree=MeSH" title="MedGen record for Advanced Triple-Negative Breast Carcinoma">Advanced Triple-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1788631" ref="tree=MeSH" title="MedGen record for Locally Advanced Triple-Negative Breast Carcinoma">Locally Advanced Triple-Negative Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1753071" ref="tree=MeSH" title="MedGen record for Recurrent Triple-Negative Breast Carcinoma">Recurrent Triple-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1711485" ref="tree=MeSH" title="MedGen record for Refractory Triple-Negative Breast Carcinoma">Refractory Triple-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718900" ref="tree=MeSH" title="MedGen record for Unresectable Triple-Negative Breast Carcinoma">Unresectable Triple-Negative Breast Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37044296">Triple-negative breast cancer: epidemiology, molecular mechanisms, and modern vaccine-based treatment strategies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Karim AM,
Eun Kwon J,
Ali T,
Jang J,
Ullah I,
Lee YG,
Park DW,
Park J,
Jeang JW,
Kang SC</span><br />
<span class="medgenPMjournal">Biochem Pharmacol</span>
2023 Jun;212:115545.
Epub 2023 Apr 11
doi: 10.1016/j.bcp.2023.115545.
<span class="bold">PMID: </span><a href="/pubmed/37044296" target="_blank">37044296</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33958794">A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bassez A,
Vos H,
Van Dyck L,
Floris G,
Arijs I,
Desmedt C,
Boeckx B,
Vanden Bempt M,
Nevelsteen I,
Lambein K,
Punie K,
Neven P,
Garg AD,
Wildiers H,
Qian J,
Smeets A,
Lambrechts D</span><br />
<span class="medgenPMjournal">Nat Med</span>
2021 May;27(5):820-832.
Epub 2021 May 6
doi: 10.1038/s41591-021-01323-8.
<span class="bold">PMID: </span><a href="/pubmed/33958794" target="_blank">33958794</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30853353">Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jiang YZ,
Ma D,
Suo C,
Shi J,
Xue M,
Hu X,
Xiao Y,
Yu KD,
Liu YR,
Yu Y,
Zheng Y,
Li X,
Zhang C,
Hu P,
Zhang J,
Hua Q,
Zhang J,
Hou W,
Ren L,
Bao D,
Li B,
Yang J,
Yao L,
Zuo WJ,
Zhao S,
Gong Y,
Ren YX,
Zhao YX,
Yang YS,
Niu Z,
Cao ZG,
Stover DG,
Verschraegen C,
Kaklamani V,
Daemen A,
Benson JR,
Takabe K,
Bai F,
Li DQ,
Wang P,
Shi L,
Huang W,
Shao ZM</span><br />
<span class="medgenPMjournal">Cancer Cell</span>
2019 Mar 18;35(3):428-440.e5.
Epub 2019 Mar 7
doi: 10.1016/j.ccell.2019.02.001.
<span class="bold">PMID: </span><a href="/pubmed/30853353" target="_blank">30853353</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(breast%20carcinoma%20by%20gene%20expression%20profile)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (175)</a></div></div>
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<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37525587">Single-cell transcriptome sequencing of B-cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
Sun K,
Liu R,
Song Y,
Lv Y,
Bi P,
Yang F,
Li S,
Zhao J,
Li X,
Chen D,
Mei J,
Yang R,
Chen K,
Liu D,
Tang S</span><br />
<span class="medgenPMjournal">Clin Transl Med</span>
2023 Aug;13(8):e1346.
doi: 10.1002/ctm2.1346.
<span class="bold">PMID: </span><a href="/pubmed/37525587" target="_blank">37525587</a><a href="/pmc/articles/PMC10390819" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37510269">Biomarkers in Breast Cancer: An Old Story with a New End.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Neves Rebello Alves L,
Dummer Meira D,
Poppe Merigueti L,
Correia Casotti M,
do Prado Ventorim D,
Ferreira Figueiredo Almeida J,
Pereira de Sousa V,
Cindra Sant'Ana M,
Gonçalves Coutinho da Cruz R,
Santos Louro L,
Mendonça Santana G,
Erik Santos Louro T,
Evangelista Salazar R,
Ribeiro Campos da Silva D,
Stefani Siqueira Zetum A,
Silva Dos Reis Trabach R,
Imbroisi Valle Errera F,
de Paula F,
de Vargas Wolfgramm Dos Santos E,
Fagundes de Carvalho E,
Drumond Louro I</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2023 Jun 28;14(7)
doi: 10.3390/genes14071364.
<span class="bold">PMID: </span><a href="/pubmed/37510269" target="_blank">37510269</a><a href="/pmc/articles/PMC10378988" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36726984">Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li W,
Wang R,
Wang W</span><br />
<span class="medgenPMjournal">Front Immunol</span>
2022;13:1029884.
Epub 2023 Jan 16
doi: 10.3389/fimmu.2022.1029884.
<span class="bold">PMID: </span><a href="/pubmed/36726984" target="_blank">36726984</a><a href="/pmc/articles/PMC9885086" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35617956">A human breast atlas integrating single-cell proteomics and transcriptomics.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gray GK,
Li CM,
Rosenbluth JM,
Selfors LM,
Girnius N,
Lin JR,
Schackmann RCJ,
Goh WL,
Moore K,
Shapiro HK,
Mei S,
D'Andrea K,
Nathanson KL,
Sorger PK,
Santagata S,
Regev A,
Garber JE,
Dillon DA,
Brugge JS</span><br />
<span class="medgenPMjournal">Dev Cell</span>
2022 Jun 6;57(11):1400-1420.e7.
Epub 2022 May 25
doi: 10.1016/j.devcel.2022.05.003.
<span class="bold">PMID: </span><a href="/pubmed/35617956" target="_blank">35617956</a><a href="/pmc/articles/PMC9202341" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35105939">Comprehensive metabolomics expands precision medicine for triple-negative breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xiao Y,
Ma D,
Yang YS,
Yang F,
Ding JH,
Gong Y,
Jiang L,
Ge LP,
Wu SY,
Yu Q,
Zhang Q,
Bertucci F,
Sun Q,
Hu X,
Li DQ,
Shao ZM,
Jiang YZ</span><br />
<span class="medgenPMjournal">Cell Res</span>
2022 May;32(5):477-490.
Epub 2022 Feb 1
doi: 10.1038/s41422-022-00614-0.
<span class="bold">PMID: </span><a href="/pubmed/35105939" target="_blank">35105939</a><a href="/pmc/articles/PMC9061756" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20carcinoma%20by%20gene%20expression%20profile%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1711)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38068930">Genetic Testing Enhances the Precision Diagnosis and Treatment of Breast Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yang T,
Li W,
Huang T,
Zhou J</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2023 Nov 22;24(23)
doi: 10.3390/ijms242316607.
<span class="bold">PMID: </span><a href="/pubmed/38068930" target="_blank">38068930</a><a href="/pmc/articles/PMC10706486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37510269">Biomarkers in Breast Cancer: An Old Story with a New End.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Neves Rebello Alves L,
Dummer Meira D,
Poppe Merigueti L,
Correia Casotti M,
do Prado Ventorim D,
Ferreira Figueiredo Almeida J,
Pereira de Sousa V,
Cindra Sant'Ana M,
Gonçalves Coutinho da Cruz R,
Santos Louro L,
Mendonça Santana G,
Erik Santos Louro T,
Evangelista Salazar R,
Ribeiro Campos da Silva D,
Stefani Siqueira Zetum A,
Silva Dos Reis Trabach R,
Imbroisi Valle Errera F,
de Paula F,
de Vargas Wolfgramm Dos Santos E,
Fagundes de Carvalho E,
Drumond Louro I</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2023 Jun 28;14(7)
doi: 10.3390/genes14071364.
<span class="bold">PMID: </span><a href="/pubmed/37510269" target="_blank">37510269</a><a href="/pmc/articles/PMC10378988" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36594618">Combined Single-Cell and Spatial Transcriptomics Reveal the Metabolic Evolvement of Breast Cancer during Early Dissemination.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu YM,
Ge JY,
Chen YF,
Liu T,
Chen L,
Liu CC,
Ma D,
Chen YY,
Cai YW,
Xu YY,
Shao ZM,
Yu KD</span><br />
<span class="medgenPMjournal">Adv Sci (Weinh)</span>
2023 Feb;10(6):e2205395.
Epub 2023 Jan 3
doi: 10.1002/advs.202205395.
<span class="bold">PMID: </span><a href="/pubmed/36594618" target="_blank">36594618</a><a href="/pmc/articles/PMC9951304" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36341760">Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zou Y,
Xie J,
Zheng S,
Liu W,
Tang Y,
Tian W,
Deng X,
Wu L,
Zhang Y,
Wong CW,
Tan D,
Liu Q,
Xie X</span><br />
<span class="medgenPMjournal">Int J Surg</span>
2022 Nov;107:106936.
Epub 2022 Sep 20
doi: 10.1016/j.ijsu.2022.106936.
<span class="bold">PMID: </span><a href="/pubmed/36341760" target="_blank">36341760</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33234169">Wnt signaling in breast cancer: biological mechanisms, challenges and opportunities.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xu X,
Zhang M,
Xu F,
Jiang S</span><br />
<span class="medgenPMjournal">Mol Cancer</span>
2020 Nov 24;19(1):165.
doi: 10.1186/s12943-020-01276-5.
<span class="bold">PMID: </span><a href="/pubmed/33234169" target="_blank">33234169</a><a href="/pmc/articles/PMC7686704" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20carcinoma%20by%20gene%20expression%20profile%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1621)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36726984">Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li W,
Wang R,
Wang W</span><br />
<span class="medgenPMjournal">Front Immunol</span>
2022;13:1029884.
Epub 2023 Jan 16
doi: 10.3389/fimmu.2022.1029884.
<span class="bold">PMID: </span><a href="/pubmed/36726984" target="_blank">36726984</a><a href="/pmc/articles/PMC9885086" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36341760">Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zou Y,
Xie J,
Zheng S,
Liu W,
Tang Y,
Tian W,
Deng X,
Wu L,
Zhang Y,
Wong CW,
Tan D,
Liu Q,
Xie X</span><br />
<span class="medgenPMjournal">Int J Surg</span>
2022 Nov;107:106936.
Epub 2022 Sep 20
doi: 10.1016/j.ijsu.2022.106936.
<span class="bold">PMID: </span><a href="/pubmed/36341760" target="_blank">36341760</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29681456">Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim C,
Gao R,
Sei E,
Brandt R,
Hartman J,
Hatschek T,
Crosetto N,
Foukakis T,
Navin NE</span><br />
<span class="medgenPMjournal">Cell</span>
2018 May 3;173(4):879-893.e13.
Epub 2018 Apr 19
doi: 10.1016/j.cell.2018.03.041.
<span class="bold">PMID: </span><a href="/pubmed/29681456" target="_blank">29681456</a><a href="/pmc/articles/PMC6132060" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28813415">CDK4/6 inhibition triggers anti-tumour immunity.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Goel S,
DeCristo MJ,
Watt AC,
BrinJones H,
Sceneay J,
Li BB,
Khan N,
Ubellacker JM,
Xie S,
Metzger-Filho O,
Hoog J,
Ellis MJ,
Ma CX,
Ramm S,
Krop IE,
Winer EP,
Roberts TM,
Kim HJ,
McAllister SS,
Zhao JJ</span><br />
<span class="medgenPMjournal">Nature</span>
2017 Aug 24;548(7668):471-475.
Epub 2017 Aug 16
doi: 10.1038/nature23465.
<span class="bold">PMID: </span><a href="/pubmed/28813415" target="_blank">28813415</a><a href="/pmc/articles/PMC5570667" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27557300">70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cardoso F,
van't Veer LJ,
Bogaerts J,
Slaets L,
Viale G,
Delaloge S,
Pierga JY,
Brain E,
Causeret S,
DeLorenzi M,
Glas AM,
Golfinopoulos V,
Goulioti T,
Knox S,
Matos E,
Meulemans B,
Neijenhuis PA,
Nitz U,
Passalacqua R,
Ravdin P,
Rubio IT,
Saghatchian M,
Smilde TJ,
Sotiriou C,
Stork L,
Straehle C,
Thomas G,
Thompson AM,
van der Hoeven JM,
Vuylsteke P,
Bernards R,
Tryfonidis K,
Rutgers E,
Piccart M;
MINDACT Investigators</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2016 Aug 25;375(8):717-29.
doi: 10.1056/NEJMoa1602253.
<span class="bold">PMID: </span><a href="/pubmed/27557300" target="_blank">27557300</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20carcinoma%20by%20gene%20expression%20profile%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (892)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37525587">Single-cell transcriptome sequencing of B-cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
Sun K,
Liu R,
Song Y,
Lv Y,
Bi P,
Yang F,
Li S,
Zhao J,
Li X,
Chen D,
Mei J,
Yang R,
Chen K,
Liu D,
Tang S</span><br />
<span class="medgenPMjournal">Clin Transl Med</span>
2023 Aug;13(8):e1346.
doi: 10.1002/ctm2.1346.
<span class="bold">PMID: </span><a href="/pubmed/37525587" target="_blank">37525587</a><a href="/pmc/articles/PMC10390819" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37510269">Biomarkers in Breast Cancer: An Old Story with a New End.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Neves Rebello Alves L,
Dummer Meira D,
Poppe Merigueti L,
Correia Casotti M,
do Prado Ventorim D,
Ferreira Figueiredo Almeida J,
Pereira de Sousa V,
Cindra Sant'Ana M,
Gonçalves Coutinho da Cruz R,
Santos Louro L,
Mendonça Santana G,
Erik Santos Louro T,
Evangelista Salazar R,
Ribeiro Campos da Silva D,
Stefani Siqueira Zetum A,
Silva Dos Reis Trabach R,
Imbroisi Valle Errera F,
de Paula F,
de Vargas Wolfgramm Dos Santos E,
Fagundes de Carvalho E,
Drumond Louro I</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2023 Jun 28;14(7)
doi: 10.3390/genes14071364.
<span class="bold">PMID: </span><a href="/pubmed/37510269" target="_blank">37510269</a><a href="/pmc/articles/PMC10378988" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36931265">Deciphering breast cancer: from biology to the clinic.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nolan E,
Lindeman GJ,
Visvader JE</span><br />
<span class="medgenPMjournal">Cell</span>
2023 Apr 13;186(8):1708-1728.
Epub 2023 Mar 16
doi: 10.1016/j.cell.2023.01.040.
<span class="bold">PMID: </span><a href="/pubmed/36931265" target="_blank">36931265</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36726984">Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li W,
Wang R,
Wang W</span><br />
<span class="medgenPMjournal">Front Immunol</span>
2022;13:1029884.
Epub 2023 Jan 16
doi: 10.3389/fimmu.2022.1029884.
<span class="bold">PMID: </span><a href="/pubmed/36726984" target="_blank">36726984</a><a href="/pmc/articles/PMC9885086" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36341760">Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zou Y,
Xie J,
Zheng S,
Liu W,
Tang Y,
Tian W,
Deng X,
Wu L,
Zhang Y,
Wong CW,
Tan D,
Liu Q,
Xie X</span><br />
<span class="medgenPMjournal">Int J Surg</span>
2022 Nov;107:106936.
Epub 2022 Sep 20
doi: 10.1016/j.ijsu.2022.106936.
<span class="bold">PMID: </span><a href="/pubmed/36341760" target="_blank">36341760</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20carcinoma%20by%20gene%20expression%20profile%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2665)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37525587">Single-cell transcriptome sequencing of B-cell heterogeneity and tertiary lymphoid structure predicts breast cancer prognosis and neoadjuvant therapy efficacy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Q,
Sun K,
Liu R,
Song Y,
Lv Y,
Bi P,
Yang F,
Li S,
Zhao J,
Li X,
Chen D,
Mei J,
Yang R,
Chen K,
Liu D,
Tang S</span><br />
<span class="medgenPMjournal">Clin Transl Med</span>
2023 Aug;13(8):e1346.
doi: 10.1002/ctm2.1346.
<span class="bold">PMID: </span><a href="/pubmed/37525587" target="_blank">37525587</a><a href="/pmc/articles/PMC10390819" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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Dummer Meira D,
Poppe Merigueti L,
Correia Casotti M,
do Prado Ventorim D,
Ferreira Figueiredo Almeida J,
Pereira de Sousa V,
Cindra Sant'Ana M,
Gonçalves Coutinho da Cruz R,
Santos Louro L,
Mendonça Santana G,
Erik Santos Louro T,
Evangelista Salazar R,
Ribeiro Campos da Silva D,
Stefani Siqueira Zetum A,
Silva Dos Reis Trabach R,
Imbroisi Valle Errera F,
de Paula F,
de Vargas Wolfgramm Dos Santos E,
Fagundes de Carvalho E,
Drumond Louro I</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2023 Jun 28;14(7)
doi: 10.3390/genes14071364.
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<div class="nl"><a target="_blank" href="/pubmed/36726984">Exploring the causality and pathogenesis of systemic lupus erythematosus in breast cancer based on Mendelian randomization and transcriptome data analyses.</a></div>
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Wang R,
Wang W</span><br />
<span class="medgenPMjournal">Front Immunol</span>
2022;13:1029884.
Epub 2023 Jan 16
doi: 10.3389/fimmu.2022.1029884.
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<div class="nl"><a target="_blank" href="/pubmed/36341760">Leveraging diverse cell-death patterns to predict the prognosis and drug sensitivity of triple-negative breast cancer patients after surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zou Y,
Xie J,
Zheng S,
Liu W,
Tang Y,
Tian W,
Deng X,
Wu L,
Zhang Y,
Wong CW,
Tan D,
Liu Q,
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<span class="medgenPMjournal">Int J Surg</span>
2022 Nov;107:106936.
Epub 2022 Sep 20
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<div class="nl"><a target="_blank" href="/pubmed/11823860">Gene expression profiling predicts clinical outcome of breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">van 't Veer LJ,
Dai H,
van de Vijver MJ,
He YD,
Hart AA,
Mao M,
Peterse HL,
van der Kooy K,
Marton MJ,
Witteveen AT,
Schreiber GJ,
Kerkhoven RM,
Roberts C,
Linsley PS,
Bernards R,
Friend SH</span><br />
<span class="medgenPMjournal">Nature</span>
2002 Jan 31;415(6871):530-6.
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<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
2023 Jan;181:103884.
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<div class="nl"><a target="_blank" href="/pubmed/35777273">Chemotherapy and gene expression profiling in older early luminal breast cancer patients: An International Society of Geriatric Oncology systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Battisti NML,
De Glas N,
Soto-Perez-de-Celis E,
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Walko C,
Lichtman SM,
Aapro M,
Cheung KL,
Biganzoli L,
Ring A,
Portielje J,
Wildiers H,
Brain E</span><br />
<span class="medgenPMjournal">Eur J Cancer</span>
2022 Sep;172:158-170.
Epub 2022 Jun 28
doi: 10.1016/j.ejca.2022.05.039.
<span class="bold">PMID: </span><a href="/pubmed/35777273" target="_blank">35777273</a><a href="/pmc/articles/PMC10861271" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34488929">Prognostic role of EGR1 in breast cancer: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Saha SK,
Islam SMR,
Saha T,
Nishat A,
Biswas PK,
Gil M,
Nkenyereye L,
El-Sappagh S,
Islam MS,
Cho SG</span><br />
<span class="medgenPMjournal">BMB Rep</span>
2021 Oct;54(10):497-504.
doi: 10.5483/BMBRep.2021.54.10.087.
<span class="bold">PMID: </span><a href="/pubmed/34488929" target="_blank">34488929</a><a href="/pmc/articles/PMC8560464" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33172959">PD-1 protein and gene expression as prognostic factors in early breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Matikas A,
Zerdes I,
Lövrot J,
Sifakis E,
Richard F,
Sotiriou C,
Rassidakis G,
Bergh J,
Valachis A,
Foukakis T</span><br />
<span class="medgenPMjournal">ESMO Open</span>
2020 Nov;5(6):e001032.
doi: 10.1136/esmoopen-2020-001032.
<span class="bold">PMID: </span><a href="/pubmed/33172959" target="_blank">33172959</a><a href="/pmc/articles/PMC7656908" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30430522">Target therapy for metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rachdi H,
Mokrani A,
Batti R,
Ayadi M,
Chraiet N,
Mezlini A</span><br />
<span class="medgenPMjournal">Tunis Med</span>
2018 Aug-Sep;96(8-9):465-471.
<span class="bold">PMID: </span><a href="/pubmed/30430522" target="_blank">30430522</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20carcinoma%20by%20gene%20expression%20profile%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (22)</a></div></div>
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