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|
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|
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|
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|
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|
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|
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|
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|
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|
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<a href="/news-events/blog" data-drupal-link-system-path="node/651">Cancer Data Science Pulse Blog</a>
|
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|
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|
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|
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|
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|
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|
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<a href="/about/staff-directory/jill-barnholtz-sloan" data-drupal-link-system-path="node/2361">CBIIT Director</a>
|
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|
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<a href="/about/nci-cio" data-drupal-link-system-path="node/42">NCI CIO</a>
|
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|
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|
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<h1>Informatics and Data Science Program (IDS)</h1>
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<h2>Informatics and Data Science Program (IDS)</h2>
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<div id="toc-h2" class="static"><a href="#project-related">Get Information on Our Projects</a></div>
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<div class="description">
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<p>Our work at IDS lays the foundation for many of NCI’s biomedical informatics and <abbr class="taxonomy-tooltip-tip" data-tippy-content="The interdisciplinary field of inquiry in which quantitative and analytical approaches, processes, and systems are developed and used to extract knowledge and insights from increasingly large and/or complex sets of data. ">data science</abbr> initiatives, giving cancer researchers (like you) the resources you need to use data more efficiently and effectively.</p><p>Our program consists of three branches: the Clinical & Translational Research Informatics Branch, the Data Ecosystems Branch, and the Computational Genomics & Bioinformatics Branch.</p><p></p><div class="callout">NCI’s Cancer Research Data Commons (CRDC) just reached a significant milestone! <a href="https://datascience.cancer.gov/news-events/news/10-years-nci-cancer-research-data-commons-highlighted-aacr-journal">Read about the CRDC</a> in a four-part series commemorating the first 10 years of this important initiative.</div><h2>Find Out What We Do</h2><h3>Clinical & Translational Research Informatics Branch (CTRIB)</h3><p><em>Branch Chief: </em><a href="https://datascience.cancer.gov/about/staff-directory/umit-topaloglu"><em>Umit Topaloglu, Ph.D.</em></a></p><p>At CTRIB, we’re working on new ways to use informatics across NCI, NIH, and the cancer research community. Our goal is to speed the translation of data-driven research into clinical practice. In particular, we’re focusing on:</p><p><em><strong>Promoting <abbr class="taxonomy-tooltip-tip" data-tippy-content="Uses a person’s genetic information to help target prevention, diagnosis, and treatment of disease. ">Precision Medicine</abbr>.</strong></em> We’re developing tools and pipelines that someday will help clinicians diagnose cancer early in the course of disease (when it’s highly treatable). We’re also helping develop new ways of predicting the best treatment for the best outcome for each person with cancer.</p><p><em><strong>Capturing and Managing Data.</strong></em> We’re working on streamlining how researchers capture and report data from NCI-sponsored precision medicine trials and clinical trials. We’re also helping to advance the use of Real-World Data (RWD) from Electronic Health Records (EHRs). We’re identifying and addressing gaps in EHR data pipelines, establishing criteria for informatic tools to support quality RWD, and advancing reliable research methods.</p><p><em><strong>Making Data Useful. </strong></em>We’re working to make certain the data you generate are useful to others in the cancer research field. We do this by developing and maintaining <abbr class="taxonomy-tooltip-tip" data-tippy-content="The rules (linguistics and logic) used to assign definitions to words. ">semantic</abbr> resources and vocabularies.</p><h3>Data Ecosystems Branch (DEB)</h3><p><em>Branch Chief: </em><a href="https://datascience.cancer.gov/about/staff-directory/tanja-davidsen"><em>Tanja Davidsen, Ph.D.</em></a></p><p>Our work at DEB centers on building, strengthening, and maintaining the <abbr class="taxonomy-tooltip-tip" data-tippy-content="The resources (both physical and virtual) that enable the flow, storage, and analysis of information. ">infrastructure</abbr> and tools that make up a sophisticated data ecosystem. We’re especially working on:</p><p><em><strong>Fostering Collaboration.</strong></em> We work closely with other government agencies, industry, and academia to stay abreast of the latest in technology. This ensures we’re tapping the latest resources and most novel ideas for cancer research, especially in the areas of informatics, high-performance computing, and artificial intelligence (AI).</p><p><em><strong>Setting Standards.</strong></em> We also work closely with international coordinating bodies to make certain that we keep pace with the latest data standards. We promote FAIR (i.e., Findable, Accessible, Interoperable, and Reusable) data principles, and ensure that data adhere to NIH’s <abbr class="taxonomy-tooltip-tip" data-tippy-content="Applies data models, standards, and processes to plan, develop, and manage data storage and retrieval systems. ">Data Management</abbr> and Sharing policy.</p><p><em><strong>Sharing Resources. </strong></em>We’re centralizing resources, such as software and training, to help others (at NCI and the broader cancer research field) access and use data. This includes looking at new ways of working with data—both in the cloud and locally, using technologies such as federated learning and edge computing.</p><h3>Computational Genomics & Bioinformatics Branch (CGBB)</h3><p><em>Branch Chief: </em><a href="https://datascience.cancer.gov/about/staff-directory/daoud-meerzaman"><em>Daoud Meerzaman, Ph.D.</em></a></p><p>At CGBB, we help solve research problems. Our staff offer skills and expertise to others (at NCI, NIH, and in the broader research community) to develop new bioinformatic and computational-genomics tools. We’re focused on:</p><p><em><strong>Advancing Research.</strong></em> We’re using the latest tools and technologies—such as proteogenomic approaches for sequencing and interpreting genomic, transcriptomics, and proteomic data—to advance cancer research.</p><p><em><strong>Developing Tomorrow’s Technology.</strong></em> Our team also is working to develop and implement new approaches, such as AI, machine learning, and algorithms, to find better ways of using data (e.g., genomic, proteomic, and imaging) to predict, diagnose, and treat cancer.</p><p><em><strong>Education and Training.</strong></em> We’re fostering the next generation of researchers and fellows through a robust training program. We also coordinate webinars and seminars, featuring renowned experts in the biomedical and technology fields, who share their insight and skills in bioinformatics and computational-genomics tools.</p>
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<p></p>
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<p></p>
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<div id="project-related">
|
||
<p></p>
|
||
<p></p>
|
||
|
||
|
||
<h2>Get Information on Our Projects</h2><p><strong>We lead many </strong><strong>data science</strong><strong>, informatics, and computational initiatives, including:</strong></p>
|
||
|
||
|
||
<div class="views-element-container"><div class="js-view-dom-id-b9e50372a1435a7ec6aee95b85298a14930c06383fc2c27f2913272173339bcf">
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<div class="views-view-responsive-grid views-view-responsive-grid--horizontal" style="--views-responsive-grid--column-count:2;--views-responsive-grid--cell-min-width:100px;--views-responsive-grid--layout-gap:25px;">
|
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<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2024-04/Bio%20Ana%20Tool%20Dev.png?itok=L3Ns3T41" width="350" height="156" alt="Image of blue topographical visual on dark background" typeof="Image" />
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||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://analysistools.cancer.gov/">Bioinformatics Analysis/Tool Development</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Delivers the latest data science approaches, including tools for data analysis and visualization.<br />
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</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2022-07/CancerDataStandardsRegistryandRepositoryProjectCard.png?itok=1GNrqQpW" width="350" height="156" alt="Photo of a male scientist carefully examining findings on his desktop computer screen. His hands are on the keyboard and he is entering information. Another scientist sits in the background and a poster showing human anatomy hangs on the wall." typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/resources/metadata">Cancer Data Standards Registry and Repository</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Provides access to oncology research, common data elements, and forms.<br />
|
||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2022-07/NCICancerResearchDataCommonsProjectCard.png?itok=yTgmw2JR" width="350" height="156" alt="Stylized image of a cloud showing repositories of data represented by circles with small icons hovering over top. The repositories include canine, imaging, genomic, and other types of data." typeof="Image" />
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||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/data-commons">Cancer Research Data Commons</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Connects you to the data ecosystem, NCI's primary platform for cancer research.<br />
|
||
</div></div></div>
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||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2024-04/Data%20Science%20Training.png?itok=6y8WWckv" width="350" height="156" alt="Image of professional taking notes by a laptop" typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/news-events/events/data-science-seminar">Data Science Training</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Brings you regular webinars and opportunities for learning the latest in data science.<br />
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||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2022-07/EnterpriseVocabularyServicesProjectCard.png?itok=6bYVK3pt" width="350" height="156" alt="Photo shows a transparent computer screen portraying icons often associated with cloud computing, including uploading and downloading to the cloud, file transfer, and file saving. A person is sitting at the screen with his hands on the keyboard. Small specks of bright lights appear in the background. " typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/resources/cancer-vocabulary">Enterprise Vocabulary Services</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Provides terminology content and tools to code, analyze, and share cancer and biomedical research information.<br />
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||
</div></div></div>
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||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2022-07/JointDesignofAdvancedComputingSolutionsforCancerProjectCard.png?itok=kc64NBno" width="350" height="156" alt="Photo shows a male sitting and facing a row of computer screens. He has his hand resting on the desk and he’s reading the screen that’s immediately in front of him. " typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/nci-department-energy-collaborations">NCI-Department of Energy Collaborations</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Advances computation, predictive models, and artificial intelligence/machine learning to accelerate precision oncology.<br />
|
||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2024-04/Real%20World%20Data.png?itok=nGcqoJ0V" width="350" height="156" alt="Image of professional touching various data icons displayed by a holographic globe" typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/real-world-data-rwd">Real-World Data</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Improves utility of Real-World Data by focusing on data quality and standards (e.g. USCDI+ Cancer).<br />
|
||
</div></div></div>
|
||
</div>
|
||
</div>
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||
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||
|
||
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||
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||
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||
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||
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||
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||
</div>
|
||
</div>
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||
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||
<p><br>
|
||
<strong>We also help support a number of other key initiatives, including:</strong></p>
|
||
<div class="views-element-container"><div class="js-view-dom-id-d3b7a7f6aa5bfa79ae7337f7cfb447d0eacc7c5eeb2b7abc883c65aa9090a5da">
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|
||
<div class="views-view-responsive-grid views-view-responsive-grid--horizontal" style="--views-responsive-grid--column-count:2;--views-responsive-grid--cell-min-width:100px;--views-responsive-grid--layout-gap:25px;">
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2023-12/ARPA-HTwitter.png?itok=4xviUlYa" width="350" height="156" alt="Abstract blue polygonal wave on black backdrop." typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/advanced-research-projects-agency-health-arpa-h-biomedical-data-fabric-bdf-toolbox">Advanced Research Projects Agency for Health Biomedical Data Fabric Toolbox</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Helps you access and make better use of biomedical data from thousands of disparate sources.<br />
|
||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2024-04/APOLLO%20Edit.png?itok=2eVv_7EO" width="350" height="156" alt="Image of three researchers in a laboratory looking at computer screen." typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/applied-proteogenomics-organizational-learning-and-outcomes-apollo-network">Applied Proteogenomics Organizational Learning and Outcomes Program</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Supports data analysis, scientific consultation, and data science training for this research network.<br />
|
||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
<div class="views-view-responsive-grid__item-inner"><div class="views-field views-field-field-image"><div class="field-content"><div class="project-img"> <img loading="lazy" src="/sites/default/files/styles/350x156/public/2024-04/CIMAC%20Edit.png?itok=VSVOIaDB" width="350" height="156" alt="Image of researcher looking at case reports, genomic, and phenotypical data with a colleague" typeof="Image" />
|
||
|
||
|
||
</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/cancer-immune-monitoring-and-analysis-centers-and-cancer-immunologic-data-center-cimac-cidc-network">Cancer Immune Monitoring and Analysis Centers</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Develops analytical solutions to help with sharing data and further characterizing cancer immunotherapy.<br />
|
||
</div></div></div>
|
||
</div>
|
||
<div class="views-view-responsive-grid__item">
|
||
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</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://datascience.cancer.gov/collaborations/clinical-trials-reporting-program-ctrp">Clinical Trials Reporting Program</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Provides informatics infrastructure and data science expertise to aid in reporting data from clinical trials.<br />
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</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://dctd.cancer.gov/MajorInitiatives/NCI-supported_activities_in_precision_medicine.htm">Precision Medicine Initiatives</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Enables genomic data to guide therapy choices, matching cancer patients to the best available trials.<br />
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</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://www.cancer.gov/ccg/research/genome-sequencing/tcga">The Cancer Genome Atlas</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Consults on new and better ways of managing data from this foundational genomic data set.<br />
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</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative/implementation/human-tumor-atlas">The Human Tumor Atlas Network</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Gives you tools to show how human cancers evolve over time, from precancerous to advanced disease.<br />
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</div></div></div><div class="views-field views-field-name"><span class="field-content"><a href="https://www.cancer.gov/ccg/research/genome-sequencing/target">Therapeutically Applicable Research to Generate Effective Treatments</a></span></div><div class="views-field views-field-field-description"><div class="field-content">Works with NCI labs to analyze genetic data from childhood cancers to help guide less toxic therapies.<br />
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|
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<div class="op-page-name"><a href="/about/staff-directory/jill-barnholtz-sloan">Jill S. Barnholtz-Sloan, Ph.D.</a> </div>
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<div class="op-page-professional-title">CBIIT Acting Director, IDS Associate Director</div>
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<div class="views-row"><div class="views-field views-field-field-published-date"><div class="field-content"><time datetime="2024-11-07T12:00:00Z">November 7, 2024</time>
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</div></div><div class="views-field views-field-title"><span class="field-content"><a href="/news-events/news/united-states-core-data-interoperability-uscdi-seeks-feedback-adverse-event-data" hreflang="en">United States Core Data for Interoperability (USCDI+) Seeks Feedback on Adverse Event Data Elements</a></span></div><div class="views-field views-field-field-short-description"><div class="field-content">If you’re working with adverse event cancer and immune-related data, USCDI+ program staff need to hear from you! See how you can give your feedback on the new USCDI+Cancer draft data set. </div></div></div>
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<div class="views-row"><div class="views-field views-field-field-published-date"><div class="field-content"><time datetime="2024-10-03T12:00:00Z">October 3, 2024</time>
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