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</div><div><span>Erythroderma</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Erythroderma</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Erythroderma is widespread redness of the skin. It is accompanied by <a test="test" href="./003226.htm">scaling</a>, peeling, and flaking of the skin, and may include itching and hair loss.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Erythroderma may occur due to:</p><ul><li>Complication of other skin conditions, such as <a test="test" href="./000853.htm">eczema</a> and <a test="test" href="./000434.htm">psoriasis</a></li><li>Reaction to medicines or some chemicals, such as phenytoin and allopurinol</li><li>Some types of cancer, such as lymphoma</li></ul><p>Sometimes the cause is unknown. It is more common in males.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Symptoms may include any of the following:</p><ul><li>Redness over 80% to 90% of the body</li><li>Scaly skin patches</li><li>Thickened skin</li><li>Skin is itchy or painful with an odor</li><li>Swelling of the arms or legs</li><li>Fast heart beat</li><li>Loss of fluids, leading to dehydration</li><li>Loss of temperature regulation by the body</li></ul><p>There may be secondary infections of the skin.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Your health care provider will ask about your symptoms and take your medical history. The provider will do a skin examination with a dermatoscope. Most of the time, the cause can be identified after the exam.</p><p>If needed, the following tests may be ordered:</p><ul><li>Biopsy of the skin</li><li>Allergy testing</li><li>Other tests to find the cause of erythroderma</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Since erythroderma can quickly lead to serious complications, the provider will start treatment right away. This usually involves strong doses of cortisone medicines to reduce inflammation. </p><p>Other treatments may include:</p><ul><li>Medicines to treat the underlying cause of erythroderma</li><li>Antibiotics for any infection</li><li>Dressings applied to the skin</li><li>Ultraviolet light</li><li>Correction of fluid and electrolyte balance</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>In serious cases, the person needs to be treated in the hospital. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Complications may include:</p><ul><li>Secondary infections that can lead to <a test="test" href="./000666.htm">sepsis</a> (bodywide inflammatory response)</li><li>Fluid loss that can result in dehydration and an imbalance of minerals (electrolytes) in the body </li><li>Heart failure</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Contact your provider right away if:</p><ul><li>Symptoms get worse or do not get better, even with treatment.</li><li>You develop new lesions.</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Prevention</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-8"><p>Risk for erythroderma may be reduced by following the provider's instructions on skin care. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Exfoliative dermatitis; Dermatitis exfoliativa; Pruritus - exfoliative dermatitis; Pityriasis rubra; Red man syndrome; Exfoliative erythroderma</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/2407t.jpg" alt="Eczema, atopic - close-up" title="Eczema, atopic - close-up" class="side-img"/><a href="../imagepages/2407.htm">Eczema, atopic - close-up</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/2232t.jpg" alt="Psoriasis - magnified x4" title="Psoriasis - magnified x4" class="side-img"/><a href="../imagepages/2232.htm">Psoriasis - magnified x4</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/19323t.jpg" alt="Atopic dermatitis" title="Atopic dermatitis" class="side-img"/><a href="../imagepages/19323.htm">Atopic dermatitis</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/2419t.jpg" alt="Exfoliation following erythroderma" title="Exfoliation following erythroderma" class="side-img"/><a href="../imagepages/2419.htm">Exfoliation following erythroderma</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Calonje E, Brenn T, Lazar AJ, Billings SD. Spongiotic, psoriasiform and pustular dermatoses. In: Calonje E, Brenn T, Lazar AJ, Billings SD, eds. <em>McKee's Pathology of the Skin</em>. 5th ed. Philadelphia, PA: Elsevier; 2020:chap 6.</p><p>James WD, Elston DM, Treat JR, Rosenbach MA, Neuhaus IM. Pityriasis rosea, pityriasis rubra pilaris, and other papulosquamous and hyperkeratotic diseases. In: James WD, Elston DM, Treat JR, Rosenbach MA, Neuhaus IM, eds. <em>Andrews' Diseases of the Skin</em>. 13th ed. Philadelphia, PA: Elsevier; 2020:chap 11.</p><p>Whittaker S. Erythroderma. In: Bolognia JL, Schaffer JV, Cerroni L, eds. <em>Dermatology</em>. 5th ed. Philadelphia, PA: Elsevier; 2024:chap 10.</p></div></div></section>
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