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<div class="h1">MTHCMSFRF (Metathesaurus CMS Formulary Reference File) Source Information</div>
</div>
</div>
<div id="source-doc-wrapper">
<div id="source-doc-intro">
<p> </p>
<p>Click on a topic below the Source Synopsis section to display details.</p>
</div>
<h2>Source Synopsis</h2>
<p><strong>Web site:</strong><br/>
<a href = "http://www.cms.gov/Medicare/Prescription-Drug-Coverage/PrescriptionDrugCovContra/RxContracting_FormularyGuidance.html" target = '_blank'>http://www.cms.gov/Medicare/Prescription-Drug-Coverage/PrescriptionDrugCovContra/RxContracting_FormularyGuidance.html</a>
</p>
<p><strong>Authority</strong><br/>
The U.S. National Library of Medicine (NLM) produces the Metathesaurus CMS Formulary Reference File (MTHCMSFRF), which is based on the Centers for Medicare &amp; Medicaid Services (CMS) Formulary Reference File (FRF).
</p>
<p><strong>Purpose</strong><br/>
The FRF is a listing of drugs that CMS Part D plan sponsors must utilize in the submission of Part D formularies to CMS for review.
</p>
<p><strong>RxNorm Scope</strong><br/>
RxNorm includes a subset of terms from the CMS FRF to produce MTHCMSFRF in each monthly and weekly RxNorm release. MTHCMSFRF information exists in the RxNorm RXNCONSO.RRF and RXNSAB.RRF files.</p>
<!--<p><strong>Metathesaurus Update Frequency</strong><br/>
MTHCMSFRF is updated annually in the Metathesaurus release as part of <a href="../RXNORM/index.html">RxNorm</a>.</p>-->
<p><strong>Sites Consulted</strong></p>
<ol>
<li>Centers for Medicare &amp; Medicaid Services. Baltimore (MD): Centers for Medicare &amp; Medicaid Services (US). Formulary guidance - Centers for Medicare &amp; Medicaid Services; [cited 2015 Mar 27]. Available from: <a href = "http://www.cms.gov/Medicare/Prescription-Drug-Coverage/PrescriptionDrugCovContra/RxContracting_FormularyGuidance.html" target = '_blank'>http://www.cms.gov/Medicare/Prescription-Drug-Coverage/PrescriptionDrugCovContra/RxContracting_FormularyGuidance.html</a></li>
</ol>
<div class="limboxcontent">
<h3><a class="jig-ncbitoggler">Metadata</a></h3>
<div class="sourcecontainer">
<table>
<tr>
<th>Field</th>
<th>Value</th>
</tr>
<!--<tr><td>Versioned Source Abbreviation</td><td>MTHCMSFRF_2014_19_03_04</td></tr>
<tr><td>Source Official Name</td><td>Metathesaurus CMS Formulary Reference File, MTHCMSFRF_2014</td></tr>
--><tr><td>Short Name</td><td>Metathesaurus CMS Formulary Reference File</td></tr>
<tr><td>Family</td><td>MTHCMSFRF</td></tr>
<tr><td>Source Restriction Level</td><td>0</td></tr>
<tr><td>Language</td><td>ENG</td></tr>
<tr><td>License Contact</td><td>RxNorm Customer Service<br />U.S. National Library of Medicine<br />8600 Rockville Pike<br />Bethesda<br />MD<br />United States<br />20894<br />(888) FIND-NLM<br />rxnorminfo@nlm.nih.gov<br />https://www.nlm.nih.gov/research/umls/rxnorm/</td></tr>
<tr><td>Content Contact</td><td>RxNorm Customer Service<br />U.S. National Library of Medicine<br />8600 Rockville Pike<br />Bethesda<br />MD<br />United States<br />20894<br />(888) FIND-NLM<br />rxnorminfo@nlm.nih.gov<br />https://www.nlm.nih.gov/research/umls/rxnorm/</td></tr>
<!--<tr><td>Citation</td><td>Metathesaurus Forms of CMS Formulary Reference File<br />2014<br />Bethesda, MD<br />National Library Of Medicine<br /></td></tr>
--></table>
<br>
</div>
<h3><a class="jig-ncbitoggler">Source Representation (currently unavailable)</a></h3>
<div class="sourcecontainer">
<!--<p>This section lists specific source data elements and provides information on their representation in RxNorm.</p>
<h4>Summary of Changes</h4>
<p>There are no changes to the original data format or to RxNorm source processing.</p>
<h4>Source Provided Files: </h4>
<p>The file is available at <a href="https://portal.drugbankplus.com/">https://portal.drugbankplus.com/</a> </p>
<p> The following file is used for RxNorm source processing.</p>
<table>
<tbody>
<tr>
<th>File Name</th>
<th>Description</th>
</tr>
<tr>
<td>Drugs.json</td>
<td>Json File</td>
</tr>
</tbody>
</table>
<br/>
<h4>Source-Provided Files: Details</h4>
<p>The following is a list of fields in the DrugBank source file used in RxNorm:</p>
<h5>File name: Drugs.json</h5>
<table>
<tbody>
<tr>
<th>Field Name</th>
<th>Description</th>
</tr>
<tr>
<td>Primary_accession_number</td>
<td>Unique DrugBank accession number consisting of a 2-letter prefix (DB) and a 5-number suffix. This ID is used to access the drug entry via the URL. If an entry is deleted, it's DrugBank ID will not be reused.</td>
</tr>
<tr>
<td>Secondary_accession_number</td>
<td>It consists of the 4-letter prefix and a 5-number suffix. Each accession number is unique to the drug's generic name. The 4-letter suffix (APRD, EXPT, BIOD, NUTR) indicates the type of drug (APRD=approved small molecule drug, EXPT=experimental drug, BIOD=biotech drug, NUTR=nutraceutical or natural product).</td>
</tr>
<tr>
<td>Name</td>
<td>Standard name of drug as provided by drug manufacturer.</td>
</tr>
<tr>
<td>Synonym</td>
<td>Alternate names of the drug</td>
</tr>
<tr>
<td>UNII</td>
<td>FDA UNII code</td>
</tr>
<tr>
<td>Language</td>
<td>Language of Synonym</td>
</tr>
</tbody>
</table>
<br/>
<p>DrugBank Field Representation in RxNorm Files:</p>
<table>
<tbody>
<tr>
<th>Field</th>
<th>RxNorm Representation</th>
</tr>
<tr>
<td>Primary_accession_number</td>
<td>RXNCONSO.CODE</td>
</tr>
<tr>
<td>Secondary_accession_number</td>
<td>RXNSAT.ATN = SID</td>
</tr>
<tr>
<td>Name</td>
<td>RXNCONSO.STR<br/>
CODE = Primary_accession_number<br/>
TTY = "IN" <br/>
SUPPRESS = "N"
</td>
</tr>
<tr>
<td>Synonym</td>
<td>RXNCONSO.STR<br/>
CODE = Primary_accession_number<br/>
TTY = "SY" or "FSY" (TTY = SY when Language field is "English"; TTY = FSY when Language field is not "English")<br/>
SUPPRESS = "N"
</td>
<tr>
<td>UNII</td>
<td>RXNSAT.ATN = FDA_UNII_CODE</td>
</tr>
<tr>
<td>Language</td>
<td>Not represented in RxNorm but used to process TTY = "SY" or "FSY"</td>
</tr>
</tbody>
</table>
<br/>
-->
</div>
<h3><a class="jig-ncbitoggler">RxNorm Representation (currently unavailable)</a></h3>
<div class="sourcecontainer">
<!--<p>This section lists RxNorm data elements and traces them back to the specific DrugBank data that populates them.</p>
<h4>Summary of Changes</h4>
<p>There are no changes to the original data format or to RxNorm source processing.</p>
<h4>Source Provided Files: </h4>
<p>The file is available at <a href="https://portal.drugbankplus.com/">https://portal.drugbankplus.com/</a> </p>
<p> The following file is used for RxNorm source processing.</p>
<table>
<tbody>
<tr>
<th>File Name</th>
<th>Description</th>
</tr>
<tr>
<td>Drugs.json</td>
<td>Json File</td>
</tr>
</tbody>
</table>
<br/>
<h4>RxNorm Identifiers:</h4>
<p>Identifiers are assigned as follows:</p>
<table>
<tbody>
<tr>
<th>Identifier</th>
<th>Origin</th>
</tr>
<tr>
<td>CODE</td>
<td>Primary_accession_number</td>
</tr>
<tr>
<td>SAUI</td>
<td>Not applicable</td>
</tr>
<tr>
<td>SCUI</td>
<td>Not applicable</td>
</tr>
<tr>
<td>SDUI</td>
<td>Not applicable</td>
</tr>
</tbody>
</table>
<br/>
<h4>Atoms (RXNCONSO):</h4>
<table>
<tbody>
<tr>
<th>Term Type</th>
<th>Origin</th>
</tr>
<tr>
<td>IN</td>
<td>Name</td>
</tr>
<tr>
<td>SY</td>
<td>Synonym<br/> (Language = "English")</td>
</tr>
<tr>
<td>FSY</td>
<td>Synonym<br/> (Language = foreign language such as Latin)</td>
</tr>
</tbody>
</table>
<br/>
<h4>Relationships (RXNREL):</h4>
<p>No relationships are provided for this source.</p>
<h4>Attributes (RXNSAT):</h4>
<table>
<tbody>
<tr>
<th>ATN</th>
<th>Origin</th>
</tr>
<tr>
<td>SID</td>
<td>Secondary_accession_number</td>
</tr>
<tr>
<td>FDA_UNII_CODE</td>
<td>UNII</td>
</tr>
</tbody>
</table>
<br/>
-->
</div>
<h3><a class="jig-ncbitoggler">Data Examples with Sample Database Queries</a></h3>
<div class="sourcecontainer">
<p>This section lists source terminology specific data examples and sample database queries using Structured Query Language (SQL) to obtain the data. For more information about RxNorm data and files, see the <a href="https://www.nlm.nih.gov/research/umls/rxnorm/docs/index.html" target="_blank">RxNorm Technical Documentation</a>.</p>
<p>MTHCMSFRF information exists in the RxNorm RXNCONSO.RRF and RXNSAB.RRF files. There are no MTHCMSFRF attributes or relationships in RxNorm.</p>
<h4>Names and Codes in RXNCONSO.RRF</h4>
<p>Here are sample source terminology code, source string, RxNorm Concept Unique Identifier (RXCUI), RxNorm term type (TTY), and suppress values.</p>
<table>
<tbody>
<tr>
<th>SOURCE_CODE</th>
<th>SOURCE_STR</th>
<th>RXCUI</th>
<th>RXNORM_TTY</th>
<th>SUPPRESS</th>
</tr>
<tr>
<td>NOCODE</td>
<td>OTC product</td>
<td>3686</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Diabetic test strips</td>
<td>126628</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Disposable insulin syringe U-100 0.5 ML</td>
<td>244822</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Disposable insulin syringe U-100 1 ML</td>
<td>244823</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Disposable insulin syringe U-100 0.3 ML</td>
<td>248458</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Gauze pads and dressing - 2 X 2 Pads</td>
<td>636967</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Insulin pen needle</td>
<td>637093</td>
<td>PT</td>
<td>N</td>
</tr>
<tr>
<td>NOCODE</td>
<td>Disposable insulin safety needles</td>
<td>724217</td>
<td>PT</td>
<td>N</td>
</tr>
</tbody>
</table>
<br/>
<p>Here is a sample database query to retrieve the data above:</p>
<p>SELECT code as source_code, str as source_str, rxcui, tty as rxnorm_tty, suppress<br />
FROM rxnconso<br />
WHERE sab = 'MTHCMSFRF';
</p>
</div>
</div>
</div>
<p class=”margin-top-5”><small>Last Reviewed: September 28, 2020</small></p>
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