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<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p id="tagline">Transforming the understanding
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<p>If you or a friend or family member are thinking about taking part in clinical research, this page contains basic information about clinical trials.</p>
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<p>Use these free education and outreach materials in your community and on social media to spread the word about mental health and related topics.</p>
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<p>Use these free digital, outreach materials in your community and on social media to spread the word about mental health.</p>
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<p>NIMH supports research at universities, medical centers, and other institutions via grants, contracts, and cooperative agreements. Learn more about NIMH research areas, policies, resources, and initiatives.</p>
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<h2>Research Conducted at NIMH (Intramural Research Program)</h2>
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<p>The Division of Intramural Research Programs (IRP) is the internal research division of the NIMH. Over 40 research groups conduct basic neuroscience research and clinical investigations of mental illnesses, brain function, and behavior at the NIH campus in Bethesda, Maryland. Learn more about research conducted at NIMH.</p>
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<h2>Priority Research Areas</h2>
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<p>Learn about NIMH priority areas for research and funding that have the potential to improve mental health care over the short, medium, and long term.</p>
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<p>Read more about the NIMH Strategic Plan for Research, Strategic Research Priorities, the anatomy of NIMH funding, and our yearly funding strategy for research grants.</p>
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<p>Explore the NIMH grant application process, including how to write your grant, how to submit your grant, and how the review process works.</p>
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<p>Learn about how NIMH manages research grants, including policies and reporting requirements.</p>
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<p>Find the latest NIH and NIMH policies, guidance, and resources for clinical research.</p>
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<p>Learn about funding opportunities for small businesses.</p>
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<div class="field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>A supplement is a process by which funds are added to an existing grant or cooperative agreement. NIMH supports several supplement programs, including Revision Applications and Administrative Supplement. The distinctions between these two types of supplements are described below.</p><p>More detailed NIMH-specific information on each supplement program, as well as the eligibility criteria and application procedures using the resources below. Applicants are encouraged to read the information provided on these linked web pages as well as the information provided in the associated notice of funding opportunity (NOFO).</p><p>In addition, applicants are strongly encouraged to contact the Program Officer assigned to their grant with questions related to developing a supplement application.</p><p>On this page:</p><ul><li><a href="#revision">Revision applications (formerly competitive supplements)</a></li><li><a href="#administrative">Administrative supplements</a></li><li><a href="#supplements">Supplements to enable continuity of research experiences of M.D./Ph.Ds. during clinical training</a></li><li><a href="#re-entry">Research supplements to promote re-entry into biomedical and behavioral research careers</a></li></ul><h2 id="revision">Revision applications (formerly competitive supplements)</h2><p>This is a request for an increase in support in a current budget period for <strong>expansion of the project’s approved scope or research protocol</strong>. The request may specify budgetary changes required for the remainder of the project period as well as for the current budget period. Revision applications are submitted using the forms, instructions, and guidelines detailed in the parent grant’s originating notice of funding opportunity . Should the parent grant’s notice be expired, applicants are encouraged to apply via the guidelines for the appropriate <a href="http://grants.nih.gov/grants/guide/parent_announcements.htm" rel="external">omnibus announcement <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>.</p><h2 id="administrative">Administrative supplements</h2><p>An <a href="/funding/grant-writing-and-application-process/administrative-supplements-to-research-grants-and-cooperative-agreements" data-entity-type="node" data-entity-uuid="24b2bb3f-3099-4f75-a2c9-87bf96ff9eea" data-entity-substitution="canonical">administrative supplement</a> is a request to provide additional funds to a grant or cooperative agreement to pay for necessary items or activities that fall <strong>within the scope</strong> of that award but were unanticipated at the time that the new or competing continuation application was submitted. (See the NIH Grants Policy Statement section on <a href="http://grants.nih.gov/grants/policy/nihgps_2012/nihgps_ch8.htm#_Change_in_Scope" rel="external">Change in Scope <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>, for more information) NIMH provides such supplements for a current budget period and future years, if necessary. An administrative supplement request is subject to an internal review and does not require peer review.</p><p>The award of an administrative supplement depends on several factors, including alignment with institute expectations/priorities, documented need, and availability of funds from NIMH's allocation for supplements. <strong>NIMH awards administrative supplements under a limited number of defined circumstances, on a case-by-case basis. </strong>Documented justification and the approval of the Program Officer and other designated NIMH staff are required.</p><p>As of July 25, 2020, the National Institutes of Health (NIH) requires recipients to submit all administrative supplement applications electronically, for both single and multi-project awards. Please follow the instructions provided in <a href="https://grants.nih.gov/grants/guide/pa-files/PA-18-591.html" rel="external">Administrative Supplements to Existing NIH Grants and Cooperative Agreements <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a> (Parent Admin Supp).</p><h2 id="supplements">Supplements to enable continuity of research experiences of M.D./Ph.Ds. during clinical training</h2><p>The purpose of the <a href="https://grants.nih.gov/grants/guide/pa-files/PA-18-642.html" rel="external">NIMH Administrative Supplement Program to Enable Continuity of Research Experiences of M.D./Ph.Ds. during Clinical Training <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a> (NOT-MH-22-060) is to support advanced research training of exceptional individuals holding the M.D./Ph.D. degree early in their research careers so that they may move more efficiently and effectively from the period of clinical training to the next stage of their research careers. This program will provide opportunities for such individuals to continue to conduct research and to enhance their research skill set while completing clinical training (i.e., during the years of residency and clinical fellowship training).</p><p>Administrative supplements must be submitted electronically. Please follow the instructions provided in NOT-MH-22-060.</p><h2>Research supplements to promote re-entry into biomedical and behavioral research careers</h2><p>This program allows PIs with active NIMH research grants to apply for administrative supplements to support individuals with high potential to re-enter an active research career after a qualifying interruption for family or other reasons. The <a href="https://orwh.od.nih.gov/career-development-education/research-supplements-promote-reentry-and-reintegration-health-related" rel="external">NIH Office of Research on Women’s Health <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>, which initiated this program, can provide co-funding..</p><p>The NIMH-funded supplements encourage such individuals to re-enter NIMH mission-relevant research careers. This program will provide administrative supplements to existing NIMH research grants for the purpose of supporting full-time or part-time research by these individuals in a program geared to bring their existing research skills and knowledge up to date. At the completion of the supplement, it is anticipated that the re-entry scientist will be able to apply for a career development (K) award, a research award (R), or some other form of independent research support.</p><p>Administrative supplements must be submitted electronically. Please follow the instructions provided in <a href="https://grants.nih.gov/grants/guide/notice-files/NOT-OD-21-134.html" rel="external">Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>.</p><h2 id="re-entry">Research supplements to promote re-entry into biomedical and behavioral research careers</h2><p>This program allows PIs with active NIMH research grants to apply for administrative supplements to support individuals with high potential to re-enter an active research career after a qualifying interruption for family or other reasons. The <a href="https://orwh.od.nih.gov/career-development-education/research-supplements-promote-reentry-and-reintegration-health-related" rel="external">NIH Office of Research on Women’s Health <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>, which initiated this program, can provide co-funding.</p><p>The NIMH-funded supplements encourage such individuals to re-enter NIMH mission-relevant research careers. This program will provide administrative supplements to existing NIMH research grants for the purpose of supporting full-time or part-time research by these individuals in a program geared to bring their existing research skills and knowledge up to date. At the completion of the supplement, it is anticipated that the re-entry scientist will be able to apply for a career development (K) award, a research award (R), or some other form of independent research support.</p><p>Administrative supplements must be submitted electronically. Please follow the instructions provided in <a href="https://grants.nih.gov/grants/guide/notice-files/NOT-OD-21-134.html" rel="external">Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"></i></a>.</p></div>
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