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href="/research">Research</a><ul class="open"><li class="inactive"><a href="/research/atniehs">At NIEHS</a><ul><li class="inactive"><a href="/research/atniehs/labs">Branches &amp; Laboratories</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb">Biostatistics &amp; Computational Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/pi/applied-statistics">Applied Statistics</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/pi/bioinformatics">Bioinformatics</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/pi/bioinformatics/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/bb/pi/computational-systems-biology">Computational Systems Biology</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/pi/constrained-statistical-inference">Constrained Statistical Inference</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/pi/statistical-epidemiology">Statistical Epidemiology</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/pi/statistical-omics">Statistical Omics</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/staff/motsinger-reif">Alison Motsinger-Reif</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/anchang">Benedict Anchang</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/weinberg">Clarice R. Weinberg</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/umbach">David M. Umbach</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/house">John S. House</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/shockley">Keith Shockley</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/li">Leping Li</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/staff/li/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/santana">Mary Díaz Santana</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/minshi">Min Shi</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/zhao">Shanshan Zhao</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/peddada">Shyamal D. Peddada</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/xu">Zongli Xu</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/staff/wheeler">Matt Wheeler</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/bb/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/seminarseries">Seminar Series</a></li><li class="inactive"><a href="/research/atniehs/labs/bb/resources">Various Resources</a><ul><li class="inactive"><a href="/research/atniehs/labs/bb/resources/career-bb">BCBB Career Opportunities</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb">Clinical Research</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce">Office of Human Research and Community Engagement (OHRCE)</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce/coc">Certificates of Confidentiality</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce/hrpp">Human Research Protection Program (HRPP)</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce/dsmb">Policy for Data and Safety Monitoring of Human Subject Research Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce/dsmb/charter">Data Safety and Monitoring Board Charter</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/ohrce/dsmb/form">Data and Safety Monitoring Board Form</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/studies/covid_smoke">A Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19 Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/myopathies">Adult and Juvenile Myositis</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/biosample">Biosample Repository Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/bpa_pk">Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/black-cohosh">Black Cohosh Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/vessel">Blood Vessel Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/bwps">Body Weight &amp; Puberty Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/bpa">BPA Biomonitoring Study in Cashiers</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/calcinosis">Calcinosis Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/cockroach">Cockroach Allergen Intervention</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/reach">Community Resiliency, Environmental Action, and Collaborations for Health (REACH) Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/cox2">Cox-2 Gene and the Immune System</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/dustmite">Dust Mite Reduction Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/e-cigs">E-Cigs and Smoking Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/infertility">Environmental Causes of Infertility</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/exposure">Environmental Exposure and Injury Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/daycare">Exposure to Indoor Allergens in Day Care Facilities</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/first_period">Girl’s Menstrual Health Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/homes">Healthy Homes</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/immunity">Immunity Cells in Blood</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/p53">Inflammatory Response to DNA Damage</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/inflammatory">Inflammatory Response to Endotoxin</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/icas">Inner-City Asthma Study (ICAS)</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/lung">Lung Inflammation Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/glucocorticoid">Metabolic Disease</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/inherited">Molecular Basis of Inherited Reproductive Disorders Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/myositis">Myositis in Military Personnel</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/nhanes">National Health &amp; Nutrition Examination Survey (NHANES)</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/nslah">National Survey of Lead &amp; Allergens in Housing (NSLAH)</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/nhales">NHALES Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/consumer">NIEHS-EPA Pilot Study of Exposure to Chemicals in Consumer Products</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/carefree">Nutrition and Menstrual Cycles Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/reproductive-endocrine">Observation of Environment and Reproductive-Endocrine Effects</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs">PEGS: Personalized Environment and Genes Study</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about">About PEGS</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/snapshots">Data Snapshots</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/i2b2">Explore PEGS with i2b2</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/faqs">Frequently Asked Questions</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/data">Study Data</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/design">Study Design</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/about/participants">Study Participants</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/team">Leadership Team</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/collaboration">Scientific Collaborations</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/collaboration/studies">Collaborative Studies</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/collaboration/process">Policies and Process</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/collaboration/proposal">Submit a Proposal</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/news">News &amp; Updates</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/news/publications">Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/pegs/contact">Contact Us</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/plasma">Plasma Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/polycystic">Polycystic Ovary Syndrome in Twin Sisters</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/psoriasis">Psoriasis Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/twin-sibs">Rheumatic Disorders in Siblings</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/tgf-beta1">RSV Infection and Asthma</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/registry">Sample Collection Registry</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/covid">Serological Surveillance for COVID-19 in Central North Carolina</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/teen-menstrual-health">Teenage Menstrual Health Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/vitamin-d">The Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical Trial</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/myorisk">The MYORISK Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/ovarian">The Ovarian Health Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/solis">The SOLIS Study</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/studies/reproductive-health">Women’s Reproductive Health Study</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda">Clinical Center, Maryland</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/resources">Additional Resources</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/resources/immunogenetic">Immunogenetic Differences Between Caucasian Women With &amp; Without Silicone Implants in Whom Myositis Develops</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/participants">Participants&#039; Information</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/participants/general">General Information</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/participants/general/parking">Parking</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/participants/general/services">Services</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/bethesda/participants/general/area">Surrounding Area</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/durham">Clinical Research Unit, North Carolina</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/durham/services">CRU Clinical Research Services</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/durham/rights">CRU Patients&#039; Bill of Rights</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/durham/cru-clinical-staff">CRU Scientists</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/durham/information-sheet">Information Sheet for NIH Employees Participating in Intramural Research Protocols</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/durham/visiting">Visiting the CRU</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/ea">Environmental Autoimmunity</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/ea/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/ea/staff/schiffenbauer">Adam Schiffenbauer</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/ea/staff/miller">Frederick W. Miller</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/ea/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/pn">Pediatric Neuroendocrinology</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/pn/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/pn/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/rpp">Reproductive Physiology &amp; Pathophysiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/rpp/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/crb/pi/rpp/staff/shekhar">Skand Shekhar</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/pi/rpp/pubs">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/crb/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/crb/seminarseries">Seminar Series</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp">Comparative &amp; Molecular Pathogenesis</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/clin-path">Clinical Pathology</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/clin-path/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/clin-path/staff/cora">Michelle Cora</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/clin-path/staff/brar">Sukhdev Brar</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/clin-path/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-lam">Comparative Medicine</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-lam/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-lam/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/laser-capture">Laser Capture Microdissection</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/laser-capture/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/mole-path">Molecular Pathology</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/mole-path/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/mole-path/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/mole-path/staff/ton">Thai-Vu Ton</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/mole-path/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/phenotyping">Mouse Embryo Phenotyping and Special Techniques</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/phenotyping/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-path">Pathology Evaluation and Peer Review</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-path/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-path/staff/patial">Sonika Patial</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/ntp-path/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support">Pathology Support</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/electron-microscopy">Electron Microscopy</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/histology">Histology</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/image-analysis">Imaging Sciences</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/immuno">Immunohistochemistry</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/immuno/equipment">Equipment</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/necropsy-support">Necropsy</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/paragone">Ashley Paragone </a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/sutton">Deloris Sutton</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/ney">Eli Ney</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/corniffe">Glenda M. Corniffe</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/jensen">Heather Jensen</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/rubino">Mark A. Rubino</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/brown">Quashana Brown</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/fisher">Renee D. Fisher</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/cunningham">Willie Cunningham</a></li><li class="inactive"><a href="/research/atniehs/labs/cmp/path-support/staff/legrande">Yvette LeGrande </a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmp/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/cmp/staff/sills">Robert Sills</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/cmb">Comparative Medicine</a></li><li class="inactive"><a href="/research/atniehs/labs/epi">Epidemiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic">Chronic Disease Epidemiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/recent-pubs">Recent Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/staff/parks">Christine Parks</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/staff/lawrence">Kaitlyn G. Lawrence</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/staff/obrien">Katie M. O&#039;Brien</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/chronic/staff/juras">Paula S. Juras</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/cancer">Environment &amp; Cancer Epidemiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/cancer/pubs">Recent Publications</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/cancer/pubs/faq">Frequently Asked Questions</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/cancer/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/fertility">Fertility and Reproductive Health</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/fertility/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/perinatal">Perinatal &amp; Early Life Epidemiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/perinatal/pubs">Recent Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/perinatal/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/puberty">Puberty and Cancer Epidemiology Group</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/puberty/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/women">Women&#039;s Health</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/pi/women/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/pi/women/pubs">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/staff/support">Scientific Program Support Team</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus">Scientists Emeriti and Special Volunteers (Retired)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus/taylor">Jack Taylor</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus/taylor/recent_publications">Recent Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus/wilcox">Allen J. Wilcox</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus/wilcox/pubs">Recent Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/emeritus/rogan">Walter J. Rogan</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/ahs">Agricultural Health Study (AHS)</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/eps">Early Pregnancy Study (EPS)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/eps/publications">Study Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/gulfstudy">GuLFSTUDY</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/life">LIFE &amp; VALID Lung Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/life/publications">Study Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/ncl">Norway Facial Clefts Study (NCL)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/ncl/publications">Study Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/moba">Norwegian Mother and Child Cohort Study (MoBa)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/moba/publications">Study Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/sister">Sister Study</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/self">Study of Environment, Lifestyle &amp; Fibroids (SELF)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/self/publications">Study Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/studies/ufs">Uterine Fibroid Study (UFS)</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/studies/ufs/publications">Study Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/epi/resources">Various Resources</a><ul><li class="inactive"><a href="/research/atniehs/labs/epi/resources/career-epi">Epidemiology Branch Career Opportunities</a></li><li class="inactive"><a href="/research/atniehs/labs/epi/resources/orgphoto">Photo Gallery</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl">Epigenetics &amp; RNA Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/cge">Chromatin &amp; Gene Expression</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/cge/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/cge/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/cge/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/etr">Eukaryotic Transcriptional Regulation</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/etr/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/etr/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/etr/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/ms">Macromolecular Structure</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/ms/resources">Resources</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/ms/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/ms/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/molecular">Molecular &amp; Genetic Epidemiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/molecular/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/molecular/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/scd">Single Cell Dynamics</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/scd/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/scd/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/stemcell">Stem Cell Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/stemcell/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/stemcell/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/systemsbiology">Systems Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/systemsbiology/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/systemsbiology/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/trd">Transcriptional Responses in Disease</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/trd/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/pi/trd/publications">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/erbl/seminars">Seminar Series</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/resources">Various Resources</a><ul><li class="inactive"><a href="/research/atniehs/labs/erbl/resources/calendar">ERBL Calendar of Events</a></li><li class="inactive"><a href="/research/atniehs/labs/erbl/resources/history">History</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl">Genome Integrity &amp; Structural Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cs">Chromosome Stability</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cs/photo_gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cs/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cs/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna">DNA Repair &amp; Nucleic Acid Enzymology</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/studies/base">Base Excision Repair</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/studies/enzymology">DNA Polymerase β</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarna/studies/cell">Genotoxic Stress</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarf">DNA Replication Fidelity</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarf/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/dnarf/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mg">Mammalian Genome</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mg/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mg/staff">Scientists and Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mg/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mgd">Mechanisms of Genome Dynamics</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mgd/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mgd/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mm">Mechanisms of Mutation</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mm/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mm/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdnar">Mitochondrial DNA Replication</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdnar/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdnar/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdrr">Mutagenesis &amp; DNA Repair Regulation</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdrr/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/mdrr/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr">Nuclear Magnetic Resonance</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/london">Bob London, Ph.D.</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/gallery">Structure Gallery</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/gallery/aids-related">AIDS Related Structures</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/gallery/allergens">Allergens</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/gallery/dna-repair">DNA Repair</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/nmr/gallery/other">Other</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/srr">Stalled Replication Repair</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/srr/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/genome">Structural Cell Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/genome/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/genome/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc">Structure Function</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/studies/dnarepair">DNA Repair Enzymes</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/studies/heparan">Heparan Sulfate/Heparin Biosynthesis</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/pi/cxc/studies/smchd1">SMCHD1</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/seminarseries">Seminar Series</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/seminarseries/gisbl_seminars">Genome Integrity &amp; Structural Biology Laboratory Seminar Series</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/seminarseries/tac_seminars">Trainees Action Committee Seminar Series</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources">Various Resources</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/retreat">GISBL Retreat</a><ul><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/retreat/2015">GISBL TAC Retreat (2015)</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/retreat/2017">GISBL TAC Retreat (2017)</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/retreat/2018">GISBL TAC Retreat (2018)</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/retreat/2024">GISBL TAC Retreat (2024)</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/inthenews">GISBL in the News</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/gisbl/resources/tac">Trainees Action Committee (TAC)</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl">Immunity, Inflammation, and Disease</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio">Cell Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/photo">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/studies/glis">GLI-Similar (GLIS) Proteins</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/studies/retinoid">Nuclear Receptor Signaling</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/cell-bio/studies/ubiquitin">Ubiquitin-Containing RAP80</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/host-def">Clinical Investigation of Host Defense</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/host-def/photo">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/host-def/methods">Research Methods</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/host-def/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/host-def/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio">Environmental Cardiopulmonary Disease</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/studies/asthma">Asthma, Allergy and the Environment</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/studies/eicosanoids">COX-Derived Eicosanoids</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-cardio/studies/cytochromes">Cytochromes P450</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/eg">Environmental Epigenomics and Disease</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/eg/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/eg/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/enviro-gen">Environmental Genetics</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/immuno-gen">Immunogenetics</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/immuno-gen/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/immuno-gen/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/immuno-gen/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/immuno-gen/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi">Integrative Genomic Epidemiology Group</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi/pace">Pregnancy And Childhood Epigenetics (PACE)</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi/pace/projects">PACE Projects</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi/pace/publications">PACE Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi/recent_publications">Recent Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/gen-epi/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/matrixbio">Matrix Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/matrixbio/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/pi/matrixbio/publications">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iidl/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/iidl/seminar">Seminar Series</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iha">Integrative Health Assessments</a><ul><li class="inactive"><a href="/research/atniehs/labs/iha/dextr">Dextr: Semi-automated Data Extraction Tool</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat">Health Assessment and Translation</a><ul><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/wang">Amy Wang</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/rooney">Andrew A. Rooney</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/beverly">Brandy Beverly</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/howdeshell">Kembra L. Howdeshell</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/taylor">Kyla W. Taylor</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/ohat/walker">Vickie R. Walker</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iha/roc">Report on Carcinogens</a><ul><li class="inactive"><a href="/research/atniehs/labs/iha/roc/lunn">Ruth M. Lunn</a></li><li class="inactive"><a href="/research/atniehs/labs/iha/roc/mehta">Suril S. Mehta</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/iha/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mtb">Mechanistic Toxicology</a><ul><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path">Molecular Pathogenesis</a><ul><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/resources">Resources</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/studies">Studies</a><ul><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/studies/animal">Animal Models of Human Disease</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/studies/effects">Effects of Bromoethane in the Uterus of Ovariectomized B6C3F1 Mice</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/studies/induction">Induction of Telomerase Activity in Human Uterine Leiomyoma Cell Lines</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/comp_path/studies/role">Role of Growth Factors in the Pathogenesis of Uterine Leiomyoma Growth in Women</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mtb/neurodevelopmental">Neurodevelopmental and Behavioral Toxicology</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/newell">Andrew J. Newell</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/mcpherson">Christopher McPherson</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/crizer">David Crizer</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/tokar">Erik Tokar</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/harry">G. Jean Harry</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/st-armour">Genna St. Armour </a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/santos">Janine Santos</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/cao">Jinyan Cao</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/birnbaum">Linda S. Birnbaum</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/marquez">Lysandra Castro Marquez</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/ferguson">Stephen S. Ferguson</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/qu">Wei Qu</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/yan">Yitang Yan</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/coulter">Sherry Coulter</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/dunlap">Paul Dunlap</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/robinson">Veronica G. Robinson</a></li><li class="inactive"><a href="/research/atniehs/labs/mtb/staff/rice">Julie Rice</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl">Molecular &amp; Cellular Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/calcium_signaling">Calcium Signaling in Health &amp; Disease</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/calcium_signaling/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/calcium_signaling/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/calcium_signaling/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/metabolism">Metabolism, Genes, and Environment</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/metabolism/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/metabolism/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/molecular">Molecular Endocrinology</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/molecular/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/molecular/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/nucleolar">Nucleolar Integrity</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/nucleolar/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/nucleolar/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/polypeptide">Post-Transcriptional Gene Expression</a><ul><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/polypeptide/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/pi/polypeptide/publications">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/mcbl/sa">Secondary Appointments</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln">Neurobiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/dn">Developmental Neurobiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/dn/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/dn/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/iv">In Vivo Neurobiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/iv/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/iv/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/iv/pubs">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/iv/tools">Various Resources</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/icp">Ion Channel Physiology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/icp/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/icp/pubs">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/nc">Neurobehavioral Circuits</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/nc/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/ne">Neuroepigenomics</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/ne/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/ne/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/neuropharm">Neuropharmacology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/neuropharm/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/neuropharm/publications">Selected Publications</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/neuropharm/studies">Studies</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/sdp">Synaptic &amp; Developmental Plasticity</a><ul><li class="inactive"><a href="/research/atniehs/labs/ln/pi/sdp/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/pi/sdp/pubs">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ln/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/ln/resources">Various Resources</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ptb">Predictive Toxicology</a><ul><li class="inactive"><a href="/research/atniehs/labs/ptb/niceatm">NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM)</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/reif">David M. Reif</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/chao">Frank G. Chao</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/parham">Frederick Parham</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/hoegberg-durdock">Helena Hoegberg-Durdock</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/erickson">Jeremy Erickson</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/hsieh">Jui-Hua Hsieh</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/mansouri">Kamel Mansouri</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/messier">Kyle P. Messier</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/kleinstreuer">Nicole Kleinstreuer</a></li><li class="inactive"><a href="/research/atniehs/labs/ptb/staff/auerbach">Scott S. Auerbach</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/ptb/spatiotemporal">Spatiotemporal Exposures and Toxicology Group</a><ul></ul></li><li class="inactive"><a href="/research/atniehs/labs/ptb/toxico">Toxicoinformatics</a><ul><li class="inactive"><a href="/research/atniehs/labs/ptb/toxico/pubs">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl">Reproductive &amp; Developmental Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi">Principal Investigators</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/male-reproduction">Male Reproduction &amp; RNA Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/male-reproduction/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/male-reproduction/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pharmaco">Pharmacogenetics</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pharmaco/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pharmaco/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/placental-cell">Placental Cell Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/placental-cell/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/placental-cell/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pregnancy">Pregnancy &amp; Female Reproduction</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pregnancy/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pregnancy/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/pregnancy/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/receptor">Receptor Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/receptor/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/receptor/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/developmental">Reproductive Developmental Biology</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/developmental/gallery">Photo Gallery</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/developmental/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/developmental/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/reproductive">Reproductive Medicine</a><ul><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/reproductive/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/pi/reproductive/pubs">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/staff">Scientists &amp; Staff</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/sa">Secondary Appointments</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/seminar_series">Seminar Series</a></li><li class="inactive"><a href="/research/atniehs/labs/rdbl/gallery">Various Resources</a></li></ul></li><li class="inactive"><a href="/research/atniehs/labs/stb">Systems Toxicology</a><ul><li class="inactive"><a href="/research/atniehs/labs/stb/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/labs/stb/staff/mcintyre">Barry S. McIntyre</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/blystone">Chad Blystone</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/rider">Cynthia Rider</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/germolec">Dori Germolec</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/dunnick">June K. Dunnick</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/ryan">Kristen R. Ryan</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/wyde">Michael E. Wyde</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/walker">Nigel J. Walker</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/frawley">Rachel Frawley</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/smith-roe">Stephanie Smith-Roe</a></li><li class="inactive"><a href="/research/atniehs/labs/stb/staff/gwinn">William Gwinn</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/dir">Intramural Research Division</a><ul><li class="inactive"><a href="/research/atniehs/dir/arsb">Administrative and Research Services</a></li><li class="inactive"><a href="/research/atniehs/dir/sio">Office of Scientific Computing</a><ul><li class="inactive"><a href="/research/atniehs/dir/sio/publications">Selected Publications</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt">Translational Toxicology Division</a><ul><li class="inactive"><a href="/research/atniehs/dtt/tools">DTT Scientific Tools</a><ul><li class="inactive"><a href="/research/atniehs/dtt/tools/dnt-diver">Developmental NeuroToxicity Data Integration and Visualization Enabling Resource (DNT-DIVER) </a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc">Scientific Director</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/olpr">Policy, Review, and Outreach</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/olpr/staff">Scientists &amp; Staff</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/ons">Portfolio Strategy and Research Management</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/ons/portfolio">Portfolio Strategy</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/ons/research-management">Scientific Research Management</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/ons/strategy">Strategic Partnerships</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo">Program Operations</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/budget">Budget and Procurement</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/adme">Chemistry and ADME Resources</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/info-data">Information and Data Management</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/brad">Brad Collins</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/georgia">Georgia Roberts</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/helen">Helen Cunny</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/stanko">Jason Stanko</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/sloop">John Sloop</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/shipkowski">Kelly Shipkowski</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/laura">Laura Hall</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/stout">Matthew Stout</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/michelle">Michelle Hooth</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/yao">Pei-Li Yao</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/shawn">Shawn Jeter</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/staff/suramya">Suramya Waidyanatha</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/opo/toxicology">Toxicology Resource Management</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports">Reports and Publications</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-01">AIDS-01</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-02">AIDS-02</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-03">AIDS-03</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-04">AIDS-04</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-05">AIDS-05</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-06">AIDS-06</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-07">AIDS-07</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-08">AIDS-08</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/aids-09">AIDS-09</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-01">NIEHS-01</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-02">NIEHS-02</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-03">NIEHS-03</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-04">NIEHS-04</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-05">NIEHS-05</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-06">NIEHS-06</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-07">NIEHS-07</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-08">NIEHS-08</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-09">NIEHS-09</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-10">NIEHS-10</a></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/reports/niehs-11">NIEHS-11</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/assoc/owdo">Workforce Development and Operations</a><ul><li class="inactive"><a href="/research/atniehs/dtt/assoc/owdo/personnel">Personnel Management Group</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan">Translational Toxicology Division Strategic Planning Framework</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/exposure">Exposure-based Research Programs</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/exposure/combined">Combined Exposures and Mixtures Program</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/exposure/consumer">Consumer Products and Therapeutics Program</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/exposure/occupational">Occupational and Inhalation Exposures Program</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/exposure/occupational/rfi-lung-models">Request for Information on the Use of In Vitro Lung Models in Inhalation Toxicology Research With Potential Application to Regulatory Decision-making</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/health">Health Effects Innovation Programs</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/health/carcinogenicity">Carcinogenicity Health Effects Innovation</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/health/cardiovascular">Cardiovascular Health Effects Innovation</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/health/developmental">Developmental Neurotoxicity Health Effects Innovation Program</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/health/developmental/chemical-list">Developmental Neurotoxicity Screening Assay Chemical List</a></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/responsive">Responsive Research Programs</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/responsive/emerging">Emerging Contaminants and Issues of Concern Program</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/responsive/sustainable">Safe and Sustainable Alternatives Program</a></li></ul></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/strength">Strengthening Capabilities Programs</a><ul><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/strength/novel">Novel Tools and Approaches Program</a></li><li class="inactive"><a href="/research/atniehs/dtt/strategic-plan/strength/cyberinfrastructure">Scientific Cyberinfrastructure Program</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/atniehs/facilities">Shared and Core Facilities</a><ul><li class="inactive"><a href="/research/atniehs/facilities/compmole">Computational Chemistry and Molecular Modeling Support</a></li><li class="inactive"><a href="/research/atniehs/facilities/bioinformatics">Integrative Bioinformatics Support</a></li><li class="inactive"><a href="/research/atniehs/facilities/mass">Mass Spectrometry 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href="/research/atniehs/facilities/metabolomics/about-us">About Us</a></li></ul></li><li class="inactive"><a href="/research/atniehs/facilities/molgencore">Molecular Genomics Core Facility</a></li><li class="inactive"><a href="/research/atniehs/facilities/mmc">Molecular Microscopy Consortium</a><ul><li class="inactive"><a href="/research/atniehs/facilities/mmc/gallery">Photo Gallery</a></li></ul></li><li class="inactive"><a href="/research/atniehs/facilities/neurobehavioral">Neurobehavioral Core Facility</a><ul><li class="inactive"><a href="/research/atniehs/facilities/neurobehavioral/publications">Selected Publications</a></li></ul></li><li class="inactive"><a href="/research/atniehs/facilities/special_techniques">Special Techniques Core Facility</a></li><li class="inactive"><a href="/research/atniehs/facilities/structural_biology">Structural Biology Core Facility</a></li><li class="inactive"><a href="/research/atniehs/facilities/trans-nih_metabolomics">Trans-NIH Metabolomics 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Scientists</a></li><li class="inactive"><a href="/research/scientistSearch/laboratories">All Research Groups</a></li></ul></li><li class="inactive"><a href="/research/supported">Grant Funded</a><ul><li class="inactive"><a href="/research/supported/dert">About the Extramural Research and Training Division</a><ul><li class="inactive"><a href="/research/supported/dert/od">Division Director</a><ul><li class="inactive"><a href="/research/supported/dert/od/vargas">Ashley Vargas</a></li><li class="inactive"><a href="/research/supported/dert/od/miller">Aubrey K. Miller</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/ertb">Exposure, Response, and Technology Branch</a><ul><li class="inactive"><a href="/research/supported/dert/ertb/collins">Jennifer Collins</a></li><li class="inactive"><a href="/research/supported/dert/ertb/ravichandran">Lingamanaidu V. Ravichandran</a></li><li class="inactive"><a href="/research/supported/dert/ertb/nadadur">Srikanth Nadadur</a></li><li class="inactive"><a href="/research/supported/dert/ertb/cui">Yuxia Cui</a></li><li class="inactive"><a href="/research/supported/dert/ertb/marzec">Jacqui Marzec</a></li><li class="inactive"><a href="/research/supported/dert/ertb/shaughnessy">Daniel Shaughnessy</a></li><li class="inactive"><a href="/research/supported/dert/ertb/shreffler">Carol Shreffler</a></li><li class="inactive"><a href="/research/supported/dert/ertb/sitaula">Sadichha Sitaula</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/geh">Genes, Environment, and Health Branch</a><ul><li class="inactive"><a href="/research/supported/dert/geh/garton">Amanda Garton</a></li><li class="inactive"><a href="/research/supported/dert/geh/dzierlenga">Anika Dzierlenga</a></li><li class="inactive"><a href="/research/supported/dert/geh/duncan">Christopher (Chris) Duncan</a></li><li class="inactive"><a href="/research/supported/dert/geh/lawler">Cindy Lawler</a></li><li class="inactive"><a href="/research/supported/dert/geh/tyson">Frederick Tyson</a></li><li class="inactive"><a href="/research/supported/dert/geh/hollander">Jonathan Hollander</a></li><li class="inactive"><a href="/research/supported/dert/geh/bollinger">Justin L. Bollinger</a></li><li class="inactive"><a href="/research/supported/dert/geh/mcallister">Kimberly A. McAllister</a></li><li class="inactive"><a href="/research/supported/dert/geh/humble">Michael Humble</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/gmb">Grants Management Branch</a><ul><li class="inactive"><a href="/research/supported/dert/gmb/graham">Alicia Graham</a></li><li class="inactive"><a href="/research/supported/dert/gmb/rogers">Caleb Rogers</a></li><li class="inactive"><a href="/research/supported/dert/gmb/asuncion">Camilo Asuncion</a></li><li class="inactive"><a href="/research/supported/dert/gmb/phillips">Clark Phillips</a></li><li class="inactive"><a href="/research/supported/dert/gmb/santos">Francoise Santos</a></li><li class="inactive"><a href="/research/supported/dert/gmb/weinstein">Irina Alva-Weinstein</a></li><li class="inactive"><a href="/research/supported/dert/gmb/williams">James Williams</a></li><li class="inactive"><a href="/research/supported/dert/gmb/greer">Jenny L. Greer</a></li><li class="inactive"><a href="/research/supported/dert/gmb/battle">Krisalaun Battle</a></li><li class="inactive"><a href="/research/supported/dert/gmb/miller">LaTavia Miller</a></li><li class="inactive"><a href="/research/supported/dert/gmb/mcgraw">Tracie McGraw</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/hsrb">Hazardous Substances Research Branch</a><ul><li class="inactive"><a href="/research/supported/dert/hsrb/trottier">Brittany A. Trottier</a></li><li class="inactive"><a href="/research/supported/dert/hsrb/carlin">Danielle Carlin</a></li><li class="inactive"><a href="/research/supported/dert/hsrb/henry">Heather F. Henry</a></li><li class="inactive"><a href="/research/supported/dert/hsrb/heacock">Michelle Heacock</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/phb">Population Health Branch</a><ul><li class="inactive"><a href="/research/supported/dert/phb/boyles">Abee L. Boyles</a></li><li class="inactive"><a href="/research/supported/dert/phb/quinn">Ashlinn K. Quinn</a></li><li class="inactive"><a href="/research/supported/dert/phb/joubert">Bonnie Joubert</a></li><li class="inactive"><a href="/research/supported/dert/phb/thompson">Claudia L. Thompson</a></li><li class="inactive"><a href="/research/supported/dert/phb/gray">Kimberly A. Gray</a></li><li class="inactive"><a href="/research/supported/dert/phb/ofallon">Liam R. O&#039;Fallon</a></li><li class="inactive"><a href="/research/supported/dert/phb/campbell">Michelle R. Campbell</a></li><li class="inactive"><a href="/research/supported/dert/phb/schug">Thaddeus Schug</a></li><li class="inactive"><a href="/research/supported/dert/phb/chamberlain">Toccara A. Chamberlain</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/pab">Program Analysis Branch</a><ul><li class="inactive"><a href="/research/supported/dert/pab/portfolio">Categorizing Our Portfolio</a></li><li class="inactive"><a href="/research/supported/dert/pab/evaluation">Evaluation Results</a></li><li class="inactive"><a href="/research/supported/dert/pab/interactive">Interactive Tools</a></li><li class="inactive"><a href="/research/supported/dert/pab/measuring-impacts">Measuring Impacts</a></li><li class="inactive"><a href="/research/supported/dert/pab/posters">Posters</a></li><li class="inactive"><a href="/research/supported/dert/pab/pubs">Publications</a></li><li class="inactive"><a href="/research/supported/dert/pab/staff">Scientists &amp; Staff</a><ul><li class="inactive"><a href="/research/supported/dert/pab/staff/drew">Christina Drew</a></li><li class="inactive"><a href="/research/supported/dert/pab/staff/pettibone">Kristianna Pettibone</a></li><li class="inactive"><a href="/research/supported/dert/pab/staff/lomotey">Mbeja Lomotey</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/dert/request">Request Technical Assistance Services</a><ul><li class="inactive"><a href="/research/supported/dert/request/confirmation-0">Confirmation</a></li></ul></li><li class="inactive"><a href="/research/supported/dert/srb">Scientific Review Branch</a><ul><li class="inactive"><a href="/research/supported/dert/srb/responsibilities">Scientific Review Officer Responsibilities</a></li><li class="inactive"><a href="/research/supported/dert/srb/staff">Staff</a><ul><li class="inactive"><a href="/research/supported/dert/srb/staff/duncan">Beverly W. 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Pearson</a></li><li class="inactive"><a href="/research/supported/dert/wet/staff/persaud">Eric Persaud</a></li><li class="inactive"><a href="/research/supported/dert/wet/staff/ahlmark">Kathy Ahlmark</a></li><li class="inactive"><a href="/research/supported/dert/wet/staff/beard">Sharon Beard</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/centers">Centers, Interagency Collaborations, and Consortia</a><ul><li class="inactive"><a href="/research/supported/centers/ehd">Centers of Excellence on Environmental Health Disparities Research</a><ul><li class="inactive"><a href="/research/supported/centers/ehd/about">About</a><ul><li class="inactive"><a href="/research/supported/centers/ehd/about/contact">Program Contact Information</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/ehd/resources">Environmental Health Disparities Resources</a></li><li class="inactive"><a href="/research/supported/centers/ehd/events">Environmental 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href="/research/supported/centers/ehd/grantees/texas">Maternal and Infant Environmental Health Riskscape (MIEHR) Research Center</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights">Highlights</a><ul><li class="inactive"><a href="/research/supported/centers/ehd/highlights/bastain">Air Pollution Exposure During Pregnancy Is Linked With Greater Risk of Depression Among Latinas</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/maldonado">Diet May Play a Role in Development of Pregnancy Complications Among Women</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/castro">Early Career Researcher Studies Exposures to Protect Babies and Mothers</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/symanski">Elaine Symanski, Ph.D. – Collaborating with Communities to Address Environmental Health Disparities</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/adamkiewicz">Gary Adamkiewicz, Ph.D. – Using Housing As an Opportunity to Improve Health</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/madres-center">MADRES Center Documents Latina Mother’s Environmental Health Concerns</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/madres-pilot">MADRES Pilot Projects Promote Environmental Health and Representation</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/madres">MADRES Story Map Depicts the Overlap of COVID-19 and Environmental Stressors</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/miehr">MIEHR Pilot Projects Support Young Investigators, Improve Health Disparity</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/beamer">Rural Health Disparities Influenced by Structural Factors, Experts Say</a></li><li class="inactive"><a href="/research/supported/centers/ehd/highlights/bastain2">Tracy Bastain Discusses Contribution of MADRES With California-Based Publication</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/centers/collaborative">Collaborative Centers in Children’s Environmental Health Research and Translation</a><ul><li class="inactive"><a href="/research/supported/centers/collaborative/about">About the Collaborative Centers in Children’s Environmental Health Research and Translation Program</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/funding">Center Funding Opportunities</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight">Center Spotlight</a><ul><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/coop-extension">OSU Researchers Talk Research Translation in NIEHS Podcast</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/flare-ups">Handout Provides Preventative Steps for Asthma Flare-Ups</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/adverse-birth">NYU Researchers Study Prenatal Exposure and Adverse Birth Outcomes in the U.S.</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/osu-opportunities">OSU Uses Social Media Metrics to Identify Opportunities to Advance Research</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/pilot">Pilot Project Funding Available</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/heat-waves">USC Developed Shareable Infographics on Heat Wave Health and Safety</a></li><li class="inactive"><a href="/research/supported/centers/collaborative/spotlight/video-highlights">Video Highlights Chemicals in Everyday Products, Ways to Reduce Exposure</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/collaborative/grantees">Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/counteract">Countermeasures Against Chemical Threats (CounterACT) Program</a></li><li class="inactive"><a href="/research/supported/centers/core">Environmental Health Sciences Core Centers</a><ul><li class="inactive"><a href="/research/supported/centers/core/about">About the EHS Core Centers</a></li><li class="inactive"><a href="/research/supported/centers/core/coe">Community Engagement Core</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight">Center Spotlight</a><ul><li class="inactive"><a href="/research/supported/centers/core/spotlight/water-contamination">Baylor Center Awardee Helps Community Address Water Contamination Concerns</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/blood-pressure">Better Health Care Access Linked To Improved High Blood Pressure Awareness, Control</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/chicago">CACHET Center Helps Protect Chicago Community from Car-shredding Operation</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/chemical-exposures">Chemical Exposures Linked to Higher Cancer Odds in Women</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/adult_health">Core Centers Study How Environment Affects Older Adult Health</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/petrochemical">Disease Rates Rise With Growing Petrochemical Production</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/worker-health">Documentary Film Features Research and Advocacy for Domestic Worker Health and Safety</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/sot">EHS Core Center Researchers Shine at SOT Conference</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/ehs-sot">EHS Core Centers Shine at SOT</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/edwards-recognized">Edwards Recognized for Research Examining Disparities in Beauty Product Use</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/pfas-testing">Engaging Students in Community PFAS Testing</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/exposing-exposome">HERCULES Center Members: Exposing the Exposome</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/hercules-exposome">HERCULES Researchers Explore the Exposome in NIEHS Podcast</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/howarth">Howarth Talks Lead and Health in NIEHS Podcast</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/pilot-projects">Mount Sinai Core Center Marks 10 Years of Pilot Projects Program, Career Development</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/cleanup">NIEHS-funded Centers, Community Partners Collaborate to Create Environmental Cleanup Resource</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/osu-health">OSU Video Provides Primer on Environmental Health</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/oral-histories">Oral Histories Inform a New Environmental Health Literacy Framework</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/fertility">PFAS Exposure Linked to Reduced Fertility in Women</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/pfas-exposure-offspring-health">PFAS Exposure in Males Altered Sperm Methylation, Triggered Downstream Effects on Offspring Health</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/pfas">PFAS-free Furniture Leads to Lower Levels of the Chemicals in Buildings</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/science-cafe">Science Cafés: Brewing Conversations in Rural Iowa and Beyond</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/hair-care">The Health Burden of Hair Care</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/microplastics-testicular">UNM Core Center Researchers Find Microplastics in Testicular Tissue</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/air-pollution">UW Core Center Researchers Work to Improve Air Quality for Washington Communities</a></li><li class="inactive"><a href="/research/supported/centers/core/spotlight/brain-health">University of Rochester Center Researchers Study Environment’s Role in Brain Health</a></li></ul></li><li class="inactive"><a href="https://tools.niehs.nih.gov/conference/ehs_core_data/index.cfm/rpage/datacollection">EHS Core Centers Data Collection Form</a></li><li class="inactive"><a href="/research/supported/centers/core/grantees">Environmental Health Sciences Core Centers Grantees</a></li><li class="inactive"><a href="/research/supported/centers/core/guidelines">Guidelines &amp; Funding Announcements</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/genome">Expanding Genome Integrity Assays to Population Studies</a><ul><li class="inactive"><a href="/research/supported/centers/genome/grantees">Funded Investigators</a><ul><li class="inactive"><a href="/research/supported/centers/genome/grantees/einstein">Albert Einstein College of Medicine</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/columbia">Columbia University</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/hutchinson">Fred Hutchinson Cancer Research Center</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/harvard">Harvard University</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/lovelace">Lovelace Biomedical &amp; Environmental Research Institute</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/minnesota">University of Minnesota</a></li><li class="inactive"><a href="/research/supported/centers/genome/grantees/alabama">University of South Alabama</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/genome/overview">Program Overview</a></li><li class="inactive"><a href="/research/supported/centers/genome/publications">Publications</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/oceans">Oceans and Human Health</a><ul><li class="inactive"><a href="/research/supported/centers/oceans/grantees">Grantees</a><ul><li class="inactive"><a href="/research/supported/centers/oceans/grantees/baylor_petrosino">Baylor College of Medicine</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/detech_obrien">D and E Technical, Inc.</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/duke_pan">Duke University</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/fgcu_parsons">Florida Gulf Coast University</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/gi-tech">Georgia Institute of Technology</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/harvard">Harvard School of Public Health</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/mcw_dellinger">Medical College of Wisconsin</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/rice_miranda">Rice University</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/seacoastscience_cowart">Seacoast Science, Inc.</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/sitka-tribe">Sitka Tribe</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/tulane-ula">Tulane University of Louisiana</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/sandiego_hamdoun">University of California, San Diego - Hamdoun</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/sandiego_moore">University of California, San Diego - Moore</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/hawaii_yanagihara">University of Hawaii at Manoa</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/um_kumar">University of Miami School of Medicine</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/uw_marcinek">University of Washington - Marcinek</a></li><li class="inactive"><a href="/research/supported/centers/oceans/grantees/woods_anderson">Woods Hole Oceanographic Institution - Anderson</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/oceans/publications">Publications</a><ul><li class="inactive"><a href="/research/supported/centers/oceans/publications/2004-2013">2004-2013</a></li><li class="inactive"><a href="/research/supported/centers/oceans/publications/2014-2019">2014-2019</a></li><li class="inactive"><a href="/research/supported/centers/oceans/publications/2020-2021">2020-2021</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/oceans/highlights">Select Program Highlights</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp">Superfund Research Program</a><ul><li class="inactive"><a href="/research/supported/centers/srp/about">About SRP</a><ul><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/news/centeroutreach.cfm">Center Outreach: Websites, Multimedia, and Newsletters</a></li><li class="inactive"><a href="/research/supported/centers/srp/about/contact_us">Contact Us</a></li><li class="inactive"><a href="/research/supported/centers/srp/about/partner">Partnerships</a></li><li class="inactive"><a href="/research/supported/centers/srp/about/strat_plan">Strategic Planning</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/outreach">Community Engagement and Research Translation</a><ul><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/outreach/outreach2.cfm">Grant Recipient Community Engagement</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/outreach/outreach3.cfm">Grant Recipient Research Translation</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/datasets">Data Management and Sharing</a><ul><li class="inactive"><a href="/research/supported/centers/srp/datasets/euc">Data Management and Integration Use 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href="/research/supported/centers/srp/events/inprogresswebinar/Biogeochemical">Biogeochemical Interactions Grant Recipients</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/occupational_24">Emerging Technologies in Occupational Health and Safety</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/ReducingExposure">Reducing Exposure to Mercury, Arsenic, and Asbestos</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/multiproject">SRP Multiproject Center Grants: Research Across Disciplines (2018)</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/multiproject_2020">SRP Multiproject Center Grants: Research Across Disciplines (2020)</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/multiproject_2023">SRP Multiproject Center Grants: Research Across Disciplines (2023)</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/water_innovation">Small Business Water Innovation</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/tce_pcbs_phthalates">TCE, PCBs, and Phthalates</a></li><li class="inactive"><a href="/research/supported/centers/srp/events/inprogresswebinar/Innovative_materials_2022">Utilizing Innovative Materials Science Approaches to Enhance Bioremediation</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/resources">Materials for Grant Recipients</a><ul><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/programs/center_administrators.cfm">Center Administrators</a></li><li class="inactive"><a href="/research/supported/centers/srp/resources/general_administrative_supplements">General Administrative Supplements</a><ul></ul></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/rtc/">SRP Data Collection Tool</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi">Public Health Impacts</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives">Archives</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances">Analytical Advances</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/bioassay">Bioassay for Dioxin and Dioxin-like Chemicals</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/development">Development and Application of the &quot;Gellyfish&quot;</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/hammock">Fundamental Discovery Points to New Therapies for Wide-ranging Diseases</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/contaminantmovement">Integrating Approaches to Predict How Contaminants Move in the Environment</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/keycharacteristics">Key Characteristics Inform Risk Assessment</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/advances/wristbands">Tracking Personal Exposures Over Time and Around the World</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical">Biomedical Health Research</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical/enterosorbents">From Water Cleanup to Edible Clays that Reduce Harmful Exposures in People and Animals</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical/pce-birth%20defects">Prenatal Exposure to Perchloroethylene (PCE) and the Incidence of Birth Defects</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical/pcb-pesticide">Residential Exposure to PCBs and Pesticides May Increase the Risk of Leukemia</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical/HEALS">SRP Researchers Tackle Arsenic from Many Angles</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/biomedical/nutrition">Using Nutrition to Reduce Harmful Effects of Pollutants</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/community">Community Engagement</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/community/derbi">Reporting Results Empowers Communities, Advances Health</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/ecology">Ecology</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/ecology/killifish">Killifish Provide Clues for Human Toxicant Susceptibility</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/ecology/wildlife">Wildlife Biomonitoring at Hazardous Waste Sites</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy">Informing Public Policy</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/arsenic">Arsenic Drinking Water Standard</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/dartmouth">Dartmouth SRP Center Informs Protective Limit for Arsenic in Water</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/removal">Removal of Chlorpyrifos and Diazinon from Retail Sales</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/hornbuckle">Revolutionizing Understanding of PCBs as Air Pollutants</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/srp_PFAS">SRP Researchers Inform Health-Related Decision Making on PFAS</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/publicpolicy/triclosan">Tackling Triclosan: Congress Recommends Review Based in Part on SRP Research</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation">Remediation Technologies</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation/bioremediation">Bioremediation of Methyl Tertiary-Butyl Ether (MTBE)</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation/sedimite">Low Cost Technology Cleans Up Contaminated Sites</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation/phytoremediation">Pioneering Interdisciplinary Approaches to Phytoremediation</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation/srpresearch">SRP Research Results in Site Deletion From EPA National Priorities List</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/remediation/cyclopure">Sustainable Technology Cleans Up PFAS in Water</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/training">Training the Next Generation of Environmental Professionals</a><ul><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/training/kcdonnelly"> K.C. Donnelly: A Legacy of Opportunity</a></li><li class="inactive"><a href="/research/supported/centers/srp/phi/archives/training/wetterhahn_25anniversary">Karen Wetterhahn: A Lasting Legacy</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/products">Publications</a><ul><li class="inactive"><a href="/research/supported/centers/srp/products/bibliometrics">Bibliometrics</a><ul><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/publications/highimpactjournals.cfm">High Impact Journals</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/publications/mostfrequentpubs.cfm">Journals Most Frequently Published in by SRP Researchers</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/publications/pubsbyyear.cfm">Number of Publications By Year</a></li></ul></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/publications/positionpieces.cfm">Reviews and Commentaries</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/publications/staffpublications.cfm">Staff Publications</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/research-briefs">Research Briefs</a></li><li class="inactive"><a href="/research/supported/centers/srp/science_digest/">Science Digest</a></li><li class="inactive"><a href="/research/supported/centers/srp/funding">SRP Funding Opportunities</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/search/index.cfm">SRP Search Tools</a></li><li class="inactive"><a href="/research/supported/centers/srp/training">Training</a><ul><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly">K.C. Donnelly Externship Award Supplement</a><ul><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2023winners">2023 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2022winners">2022 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2021winners">2021 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2020winners">2020 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2019winners">2019 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2018winners">2018 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2017winners">2017 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2016winners">2016 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2015winners">2015 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2014winners">2014 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2013winners">2013 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2012winners">2012 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/2011winners">2011 Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/donnelly/externshipguidelines">K.C. Donnelly Externship Guidelines</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn">Karen Wetterhahn Memorial Award</a><ul><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/armijo">2022 - Amanda Armijo, MIT</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/mills">2023 – Rollie Mills, University of Kentucky</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/frazar">2021 – Molly Frazar, University of Kentucky</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/Kay">2020 – Jennifer Kay, Massachusetts Institute of Technology</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/elkin">2019 - Elana Elkin, University of Michigan</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/kim">2018 - Stephanie Kim, Boston University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/gutierrez">2017 - Angela Gutierrez, University of Kentucky</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/martin">2016 - Elizabeth Martin, University of North Carolina at Chapel Hill</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/jayasundara">2015 – Nishad Jayasundara, Duke University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/newsome">2014 – Bradley Newsome, University of Kentucky</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/hammond">2013 – Corin Hammond, University of Arizona</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/baker">2012 – Nicki Baker, University of Kentucky</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/ramirez-andreotta">2011 - Monica Ramirez-Andreotta, University of Arizona</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/kozulhorvath">2010 - Courtney Kozul-Horvath, Dartmouth College</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/radloff">2009 - Karrie Radloff, Columbia University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/senier">2008 - Laura Senier, Brown University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/karimi">2007 - Roxanne Karimi, Dartmouth College</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/timmelaragy">2006 - Alicia R. Timme-Laragy, Duke University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/bredfeldt">2005 - Tiffany Bredfeldt, University of Arizona</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/spuches">2004 - Anne Spuches, Dartmouth College</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/mendez">2003 - Monica Mendez, University of Arizona</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/craft">2002 - Elena Craft, Duke University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/adair">2001 - Blakely M. Adair, Texas Tech University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/andrew">2000 - Angeline Andrew, Dartmouth College</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/harrahy">1999 - Elisabeth Harrahy, Colorado State University</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/healy">1998 - Sheila Healy, University of Arizona</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/wetterhahn/wetterhahn_guidelines">Annual Karen Wetterhahn Memorial Award Application Guidelines</a></li></ul></li><li class="inactive"><a href="/research/supported/centers/srp/training/opportunities">Opportunities for Trainees</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/poster_winners">SRP Annual Meeting Poster Winners</a></li><li class="inactive"><a href="/research/supported/centers/srp/training/spa">Student / Postdoc / Alumni Network</a><ul></ul></li><li class="inactive"><a href="/research/supported/centers/srp/training/videos">Trainee Videos</a></li></ul></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/news/whatsnew.cfm">What&#039;s New</a></li><li class="inactive"><a href="https://tools.niehs.nih.gov/srp/sites/www.cfm">Where We Work</a></li><li class="inactive"><a href="/research/supported/centers/srp/programs">Who We Fund</a><ul><li class="inactive"><a href="/research/supported/centers/srp/programs/r01">Individual Research Grants</a></li><li class="inactive"><a href="/research/supported/centers/srp/programs/p42">Multiproject Center Grants</a></li><li class="inactive"><a href="/research/supported/centers/srp/programs/r25">Occupational Health and Safety Training Education Programs on Emerging Technologies</a></li><li class="inactive"><a href="/research/supported/centers/srp/programs/r43">Small Business Innovation Research Grants</a></li><li class="inactive"><a href="/research/supported/centers/srp/programs/r21">Time-Sensitive Research Grants</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/exposure">Environmental Exposure Research</a><ul><li class="inactive"><a href="/research/supported/exposure/air_pollution">Air Pollution</a></li><li class="inactive"><a href="/research/supported/exposure/endocrine">Endocrine Disruptors</a></li><li class="inactive"><a href="/research/supported/exposure/hhear">Exposure Analysis Resources</a><ul><li class="inactive"><a href="/research/supported/exposure/hhear/grantees">Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/exposure/bio">Exposure Biology and the Exposome</a></li><li class="inactive"><a href="/research/supported/exposure/mixtures">Mixtures</a><ul><li class="inactive"><a href="/research/supported/exposure/mixtures/prime_program">Powering Research Through Innovative Methods for Mixtures in Epidemiology (PRIME) Program</a><ul><li class="inactive"><a href="/research/supported/exposure/mixtures/prime_program/prime-grantees">Grantees</a></li><li class="inactive"><a href="/research/supported/exposure/mixtures/prime_program/events">PRIME Events</a></li><li class="inactive"><a href="/research/supported/exposure/mixtures/prime_program/publications">Publications</a></li><li class="inactive"><a href="/research/supported/exposure/mixtures/prime_program/toolbox">Toolbox</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/exposure/nanohealth">Nano Environmental Health and Safety (Nano EHS)</a><ul></ul></li><li class="inactive"><a href="/research/supported/exposure/pfas">Per- and Polyfluoroalkyl Substances (PFAS)</a><ul><li class="inactive"><a href="/research/supported/exposure/pfas/highlights">Highlighted Research</a><ul><li class="inactive"><a href="/research/supported/exposure/pfas/highlights/external/metabolic-changes">New Research Sheds Light on Metabolic Changes Associated with PFAS 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class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/chaps">Children’s Health and Air Pollution Study (CHAPS) Cohort Maintenance</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/e3gen">E3Gen: Multigenerational Effects of Toxicant Exposures on Life Course Health and Neurocognitive Outcomes in the ELEMENT Birth Cohorts</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/heals">Enhancement and Maintenance of the Health Effects of Arsenic Longitudinal Study (HEALS) Cohort</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/rhode-island">Enriching the Rhode Island Child Health Study (RICHS)</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/earli">Expanding the Value of the EARLI Study: Small Cohort with Big Data</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/fcc">Fernald Community Cohort: Research Resource for Environmental Epidemiology</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/nest">Follow-up and Maintenance of the Newborn Epigenetics STudy (NEST) Cohort</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/viva">Maintain and Enrich Resource Infrastructure for Project Viva: A Pre-birth Cohort With Follow Up Into Adolescence</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/isa">Maintaining and Enriching the Infants Environmental Health Study (ISA)</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/chamacos">Maintaining and Expanding the CHAMACOS Epidemiology Cohort Infrastructure for Future Generations</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/maternal-child-cohort">Maintenance and Enhancement of the Atlanta African American Maternal-Child Cohort: Exposome Profiling via High-resolution Metabolomics and Integration of Microbiome-Metabolome-Epigenome Data</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/nhs3">Nurses Health Study 3 (NHS3)</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/cares">Retention, Maintenance and Enhancement of the Communities Actively Researching Exposure Study (CARES)</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/seychelles">Seychelles Child Development and Nutrition Study</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/cl">Support for Infrastructure of Childhood Leukemia Environmental Research</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/progress">The Programming Research in Environment and Social Stressors (PROGRESS) Cohort</a></li><li class="inactive"><a href="/research/supported/epidemiology/maintaining-cohorts/grantees/epidemiology">To Maintain and Enrich Resource Infrastructure for Existing Environmental Epidemiology Cohorts</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/epidemiology/cohorts">NIEHS-Funded Epidemiology Resources Faceted Search Tool</a></li></ul></li><li class="inactive"><a href="/research/supported/health">Health Impacts Research</a><ul><li class="inactive"><a href="/research/supported/health/autism">Autism</a><ul><li class="inactive"><a href="/research/supported/health/autism/grantees">Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/health/childrens">Children&#039;s Health</a></li><li class="inactive"><a href="/research/supported/health/developmental">Developmental 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Administrative Supplement</a></li></ul></li><li class="inactive"><a href="/research/supported/success">Stories of Success</a><ul><li class="inactive"><a href="/research/supported/success/2025">2025</a><ul><li class="inactive"><a href="/research/supported/success/2025/cory-slechta">February 24 - RIVER Researcher Links Environmental Exposures and Neurological Dysfunction</a></li></ul></li><li class="inactive"><a href="/research/supported/success/2024">2024</a><ul><li class="inactive"><a href="/research/supported/success/2024/xiao">December 18 - Reproductive Replicas Advance Women’s Health Research</a></li><li class="inactive"><a href="/research/supported/success/2024/rajagopalan">December 17 - Examining Connections Between Air Pollution, Circadian Rhythms, and Disease</a></li><li class="inactive"><a href="/research/supported/success/2024/zylka">October 24 - Unraveling the Genetic and Environmental Factors Behind Neurodevelopmental Disorders</a></li><li class="inactive"><a href="/research/supported/success/2024/cormier">September 30 - Revealing the Effects of Air Pollution Across the Life Span</a></li><li class="inactive"><a href="/research/supported/success/2024/kay">September 26 - Connecting the Dots Between DNA Damage, Hormonal Signaling, and Breast Cancer</a></li><li class="inactive"><a href="/research/supported/success/2024/fry">September 16 - From Cells to Society: Protecting Children and Pregnant Women From Environmental Harms</a></li><li class="inactive"><a href="/research/supported/success/2024/lomnicki">May 2 - Studying Free Radicals to Improve Air Quality</a></li><li class="inactive"><a href="/research/supported/success/2024/volk">May 1 - Untangling the Genetic and Environmental Complexities of Autism Spectrum Disorder</a></li><li class="inactive"><a href="/research/supported/success/2024/sung">March 19 - Unraveling the Mysteries of DNA Repair</a></li><li class="inactive"><a href="/research/supported/success/2024/el-hayek">March 12 - From Lebanon to New Mexico: Studying How Contaminants Interact with Plant and Human Health</a></li><li class="inactive"><a href="/research/supported/success/2024/wise">February 1 - Applying the One Environmental Health Approach to Hexavalent Chromium</a></li></ul></li><li class="inactive"><a href="/research/supported/success/2022">2022</a><ul><li class="inactive"><a href="/research/supported/success/2022/hajat">December 7, 2022 - Uncovering Relationships Between Air Pollution, Psychosocial Stressors, and Cardiovascular Disease</a></li><li class="inactive"><a href="/research/supported/success/2022/cardenas">September 1, 2022 - Combining Biostatics and Genomics Research to Prevent Disease</a></li><li class="inactive"><a href="/research/supported/success/2022/payne-sturges">August 23, 2022 - Embracing the Complexity of Environmental Health Challenges</a></li><li class="inactive"><a href="/research/supported/success/2022/stapleton">August 5, 2022 - Tracking Nanoparticles Across the Placental Barrier</a></li><li class="inactive"><a href="/research/supported/success/2022/groopman">June 16, 2022 - Fleshing Out a Fungal Toxin’s Role in Liver Cancer</a></li><li class="inactive"><a href="/research/supported/success/2022/chen">May 2, 2022 - Exploring the Cardiovascular Effects of Arsenic Exposure</a></li><li class="inactive"><a href="/research/supported/success/2022/wang">April 13, 2022 - Visualizing DNA Damage Through a Molecular Lens</a></li><li class="inactive"><a href="/research/supported/success/2022/sanchez">April 19, 2022 - Uncovering the Link Between Metals and Disease</a></li><li class="inactive"><a href="/research/supported/success/2022/monti">April 19, 2022 - Preventing Disease Through Bioinformatics</a></li><li class="inactive"><a href="/research/supported/success/2022/gaddameedhi">April 15, 2022 - Exploring the Role of the Biological Clock in Gene-environment Interactions</a></li><li class="inactive"><a href="/research/supported/success/2022/dolinoy">March 11, 2022 - Connecting the Epigenome to Environmental Health</a></li><li class="inactive"><a href="/research/supported/success/2022/ramirez-andreotta">February 17, 2022: Engaging Communities to Improve Well-being</a></li><li class="inactive"><a href="/research/supported/success/2022/sparks">January 20, 2022 - Applying Novel Techniques to Understand Developmental Toxicity in Bone</a></li></ul></li><li class="inactive"><a href="/research/supported/success/2023">2023</a><ul><li class="inactive"><a href="/research/supported/success/2023/herting">December 12 - Exposing Connections Between Air Pollution and Early Brain Development</a></li><li class="inactive"><a href="/research/supported/success/2023/petriello">November 29 - Gut Check: Studying Environmental Connections Between Diet and Disease</a></li><li class="inactive"><a href="/research/supported/success/2023/sweasy">October 11 - Connecting DNA, Autoimmunity, and the Environment</a></li><li class="inactive"><a href="/research/supported/success/2023/kioumourtzoglou">September 19, 2023 - Harnessing Data to Track Understudied Air Pollution Impacts</a></li><li class="inactive"><a href="/research/supported/success/2023/rahman">August 10, 2023 - What Makes Us Tick: Smoking’s Effect on Our Biological Clock</a></li><li class="inactive"><a href="/research/supported/success/2023/chen">May 8, 2023 - Sniffing Out Signs of Neurodegeneration</a></li><li class="inactive"><a href="/research/supported/success/2023/ghosh">March 23, 2023 - Enhancing Remediation Technology to Clean Up Contaminants</a></li><li class="inactive"><a href="/research/supported/success/2023/fleisch">February 24, 2023 - Linking Early Life Exposures with Lifelong Health</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/timesensitive">Time-Sensitive Research Opportunities in Environmental Health</a><ul><li class="inactive"><a href="/research/supported/timesensitve/grantees">Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/translational">Translational Science, Outreach, and Education</a><ul><li class="inactive"><a href="/research/supported/translational/community">Community-engaged Research and Citizen Science</a><ul><li class="inactive"><a href="/research/supported/translational/community/acat">Alaska Community Action on Toxics (ACAT)</a></li><li class="inactive"><a href="/research/supported/translational/community/enact">Environmental Health for Alabama Communities (ENACT)</a></li><li class="inactive"><a href="/research/supported/translational/community/gardenroots">Gardenroots: The Dewey-Humboldt, Arizona, Garden Project</a></li><li class="inactive"><a href="/research/supported/translational/community/mercury">Grand Lake Watershed Mercury Study</a></li><li class="inactive"><a href="/research/supported/translational/community/gulfcoast">Gulf Coast Health Alliance: Health Risks Related to the Macondo Spill (GC-HARMS)</a></li><li class="inactive"><a href="/research/supported/translational/community/hapi">HAPI: Putting Community Engaged Research into Action to Address Childhood Asthma</a></li><li class="inactive"><a href="/research/supported/translational/community/imperial">Imperial County Community Air Monitoring Project</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/ehsic">Environmental Health Science Education</a><ul><li class="inactive"><a href="/research/supported/translational/ehsic/highlights">Select Program Highlights</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/implementation">Implementation Science in Environmental Health</a><ul><li class="inactive"><a href="/research/supported/translational/implementation/cfg">Currently Funded Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph">Partnerships for Environmental Public Health (PEPH)</a><ul><li class="inactive"><a href="/research/supported/translational/peph/about">About PEPH</a></li><li class="inactive"><a href="/research/supported/translational/peph/contactus">Contact PEPH</a></li><li class="inactive"><a href="/research/supported/translational/peph/newsletter/">Current PEPH Newsletter</a></li><li class="inactive"><a href="/research/supported/translational/peph/events">Events</a></li><li class="inactive"><a href="/research/supported/translational/peph/foa">Funding Opportunities</a></li><li class="inactive"><a href="/research/supported/translational/peph/grantee-highlights">Grantee Highlights</a><ul><li class="inactive"><a href="/research/supported/translational/peph/grantee-highlights/2024">2024</a></li><li class="inactive"><a href="/research/supported/translational/peph/grantee-highlights/2023">2023</a></li><li class="inactive"><a href="/research/supported/translational/peph/grantee-highlights/2022">2022</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/resources">PEPH Resources</a><ul><li class="inactive"><a href="/research/supported/translational/peph/resources/communities">Healthy Communities</a></li><li class="inactive"><a href="/research/supported/translational/peph/resources/families">Healthy Families</a></li><li class="inactive"><a href="/research/supported/translational/peph/resources/spaces">Healthy Spaces</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts">Podcasts: Environmental Health Chat</a><ul><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024">2024</a><ul><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/coop-extension">November 25 - Partnerships to Advance Research Translation</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/pesticide-child-care-centers">October 23 - Reducing Pesticide Use in Child Care Centers</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/sep24_exposures-microplastics">September 24 - Understanding Exposures to Microplastics and Nanoplastics</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/aug14_menopause">August 14 - Menopause and the Environment</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/artificial-turf-and-your-health">May 20 - Artificial Turf and Your Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/feb26_prehs">February 26 - Incorporating the Environment into Maternal and Child Health Care</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2024/jan3_radon">January 3 - Keeping Your Home Safe From Radon</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023">2023</a><ul><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/feb22_drinking-water">February 22 - Reducing Exposure to Disinfection Byproducts in Drinking Water</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/oct2_lead">October 2 - Protecting Communities From Lead Exposure</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/july10_exposome">July 10 - The Exposome and Health (Part 1)</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/aug9_exposome">August 9 - The Exposome and Health (Part 2)</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/dec5_pfas">December 5 - PFAS in Drinking Water: Responding to Community Concerns</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/june15_firefighter">June 15 - Protecting Firefighter Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/apr14_nature">April 14 - Spending Time in Nature May Slow Alzheimer’s, Parkinson’s Disease Progression</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2023/jan6_workers-health">January 6 - Combining Technology and Training to Protect Workers’ Health</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022">2022</a><ul><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022/aug17_saferfish">August 17 - Campaign Promotes Eating Safer Fish</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022/sep23_pfas-your-health">September 23 - PFAS and Your Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022/july13_algal-blooms">July 13 - Community Science Aids Harmful Algal Blooms Research</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022/apr13_atlanta">April 13 - Community-engaged Research Leads to Soil Cleanup</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2022/mar16_saltonsea">March 16 - The Shrinking Salton Sea and Children’s Health</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021">2021</a><ul><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/dec16_microbiome">December 16 - Parkinson’s Disease, Pesticides, and the Gut Microbiome</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/feb8_smokefree">February 8 - Using Culturally Appropriate Messages to Promote Smoke-Free Homes</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/sep27_botanical">September 27 - Botanical Safety</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/aug19_youth">August 19 - Engaging Youth in Research</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/july30_wildfire">July 30 - Wildfire Smoke and Children’s Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/june22_nutrition">June 22 - Eating a Healthy Diet to Protect Against Pollution</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/april14_dogs">April 14 - Dogs Shed Light on Chemical Exposures and Disease</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/mar17_science">March 17 - Using Implementation Science to Move Environmental Health Discoveries into the Real-world</a></li><li class="inactive"><a href="/research/supported/translational/peph/podcasts/2021/feb23_greening">February 23 – Greening Neighborhoods to Improve Health</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/translational/peph/prog">Programs</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars">Webinars</a><ul><li class="inactive"><a href="/research/supported/translational/peph/webinars/air-monitor1">Air Monitoring Networks – Session I: Deciding Whether to Implement an Air Monitoring Network – Co-developing a Plan with Community Partners</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/air-monitor2">Air Monitoring and Community Engagement – Session II: Partnerships and Impact – How an Air Monitoring Network Can Benefit the Community</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/air-monitor3">Air Monitoring and Community Engagement – Session III: When Things Go Sideways – Overcoming Obstacles and Collaborative Problem Solving with Community Partners</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/community-health-workers">Community Health Workers: Building Cultural Bridges to Address Environmental Public Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/ehp-mobile1">Environmental Public Health Mobile Apps – Session One</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/ehp-mobile2">Environmental Public Health Mobile Apps – Session Two</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/meet-the-editors">Meet the Editors</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/plastic_and_human_health">Plastic and Human Health</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/safety-health-training">Safety &amp; Health Training for American Indians &amp; Alaska Natives in the Western U.S. – Session One</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/safety-health-training2">Safety &amp; Health Training for American Indians &amp; Alaska Natives in the Western U.S. – Session Two</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/social-stress">Social Stress and Susceptibility</a></li><li class="inactive"><a href="/research/supported/translational/peph/webinars/wastewater_surveillance">Wastewater Surveillance - Monitoring COVID-19 to Protect Public Health</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/translational/rta">Research to Action</a><ul><li class="inactive"><a href="/research/supported/translational/rta/cfg">Currently Funded Grantees</a><ul><li class="inactive"><a href="/research/supported/translational/rta/cfg/app">A University-community Partnership to Reduce Exposure to Disinfection By-products in Appalachia</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/indiana">Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents’ Concerns, Neurotoxic Effects, and Exposure Reduction</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/nyu">Building Food Sovereignty, Sustainability, and Better Health in Environmentally Impacted Native Americans</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/pbb">Collaborative Research and Action: Empowering an Exposed Community</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/caphe">Community Action to Promote Healthy Environments</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/ua">El Trabajo no te Debe Dañar: Reduction of Hazardous Exposures in Small Businesses through a Community Health Worker Intervention</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/mcw">Gigiigooinaan (Our Fish): A New Advisory to Promote Anishinaabe Health and Wellness</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/lasvoces">Los Angeles Voices on Oil, Community, Environment, and Salud (LAS VOCES) Study</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/ssi">PFAS-REACH (Research, Education, and Action for Community Health)</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/emory">Prevention of Paralytic Shellfish Poisoning in Subsistence Shellfish Harvest Communities of Southeast Alaska</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/uky">Radon on the RADAR</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/arizona">Restoring Northeast Cape for the Health and Well-being of the Yupik Communities of St. Lawrence Island (Sivuqaq), Alaska</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/qc">Safe and Just Cleaners: Reducing Exposure to Toxic Cleaning Chemical Products Among Low-Wage Immigrant Latino Community Members</a></li><li class="inactive"><a href="/research/supported/translational/rta/cfg/usc">The Salton Sea and Children’s Health: Assessing Imperial Valley Respiratory Health and the Environment</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/rta/pfg">Previously Funded Grantees</a><ul><li class="inactive"><a href="/research/supported/translational/rta/pfg/rand">Addressing Fugitive Chemical Health Risks Through Community-based Actions Study</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/karr">Aggravating Factors of Asthma in Hispanic Farm Workers</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/lu">City of Boston Housing Partnership for Environmental Public Health Exploration and Mitigation</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/uk">Community-Engaged Research and Action to Reduce Respiratory Disease in Appalachia</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/kamen">Environmental Determinants of Autoimmunity</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/morse">Green Cleaning: Exposure Characterization and Adoption</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/uw">Home Air In Agriculture - Pediatric Intervention Trial (HAPI)</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/ryan">Impact of Traffic-Related Particles on Asthma for Students in an Urban School District</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/mccauley">Improving Pregnancy Health Among Florida Farmworkers</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/schaider">Mercury Exposure from Fish Consumption in Subsistence Fishers in Rural Oklahoma</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/uc">Promoting Healthy Seafood Choices in Asian Communities</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/silbergeld">Reducing Exposures to Pathogens from Industrial Food Animal Production</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/mcbride">Reducing Exposures to Soil Contaminants from Urban Gardening</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/ut">Sustainable Solutions to Metal Air Pollution in Disadvantaged Neighborhoods</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/lemasters">The Libby Community: Childhood Health Investigation and Exposure Follow-Up Study (CHIEFS)</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/phi">Use of Community-Based Mapping and Monitoring to Reduce Air Pollution Exposures</a></li><li class="inactive"><a href="/research/supported/translational/rta/pfg/wilson">Use of a Community-University Partnership to Eliminate Environmental Stressors</a></li></ul></li></ul></li><li class="inactive"><a href="/research/supported/translational/sbir">Small Business Programs (SBIR/STTR)</a><ul><li class="inactive"><a href="/research/supported/translational/sbir/townhall">SBIR/STTR Town Hall Meeting</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/victer">Virtual Consortium for Translational / Transdisciplinary Environmental Research (ViCTER)</a><ul><li class="inactive"><a href="/research/supported/translational/victer/grantees">Grantees</a></li></ul></li><li class="inactive"><a href="/research/supported/translational/wtp">Worker Training Program</a></li></ul></li><li class="inactive"><a href="/research/supported/whatsnew">What&#039;s New</a><ul><li class="inactive"><a href="/research/supported/centers/srp/news/efactorarticles">SRP Environmental Factor 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href="/research/programs/disaster/training-education">Training &amp; Education</a></li></ul></li><li class="inactive"><a href="/research/programs/east_palestine">East Palestine (Ohio) Train Derailment Research Response</a></li><li class="inactive"><a href="/research/programs/ehlc">Environmental Health Language Collaborative</a><ul><li class="inactive"><a href="/research/programs/ehlc/about">About EHLC</a></li><li class="inactive"><a href="/research/programs/ehlc/use-cases">Environmental Health Use Cases</a><ul><li class="inactive"><a href="/research/programs/ehlc/use-cases/bio">Biomarkers and Biological Processes of Exposure Use Case</a></li><li class="inactive"><a href="/research/programs/ehlc/use-cases/concluded">Concluded Use Case Working Groups</a></li><li class="inactive"><a href="/research/programs/ehlc/use-cases/discovery">Data Discovery Use Case</a></li><li class="inactive"><a href="/research/programs/ehlc/use-cases/harmonization">Data Harmonization Use 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href="/research/programs/geh/podcasts/2024">2024</a><ul><li class="inactive"><a href="/research/programs/geh/podcasts/2024/august_10-years">August - Disaster Research Response Program Marks 10 Years</a></li></ul></li></ul></li><li class="inactive"><a href="/research/programs/geh/partnerships">WHO Collaborating Centre for Environmental Health Sciences</a><ul><li class="inactive"><a href="/research/programs/geh/partnerships/network">Network of WHO Collaborating Centres for Children&#039;s Environmental Health</a><ul><li class="inactive"><a href="/research/programs/geh/partnerships/network/centres">Centres in the Network</a><ul><li class="inactive"><a href="/research/programs/geh/partnerships/network/centres/mexico">Center for Applied Research in Environment and Health, Autonomous University of San Luis Potosí</a></li><li class="inactive"><a href="/research/programs/geh/partnerships/network/centres/canada">Children’s Environmental Health Clinic (ChEHC) WHO CC in CEH Department of 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href="/research/resources/databases/orio">Online Resource for Integrative Omics (ORIO)</a></li><li class="inactive"><a href="/research/resources/databases/p53">p53 Resources</a></li><li class="inactive"><a href="/research/resources/databases/snpinfo">SNPinfo Web Server</a></li><li class="inactive"><a href="/research/resources/databases/spintrap">Spin Trap Database</a></li></ul></li><li class="inactive"><a href="/research/resources/epresr">Electron Paramagnetic Resonance/Electron Spin Resonance (EPR/ESR)</a><ul><li class="inactive"><a href="/research/resources/epresr/esrs_database">Electron Spin Resonance Software Database</a></li><li class="inactive"><a href="/research/resources/epresr/sensitivity">Public Test of Electron Spin Resonance Sensitivity</a></li><li class="inactive"><a href="/research/resources/epresr/resources">EPR/ESR Resources</a></li><li class="inactive"><a href="/research/resources/epresr/performance">EPR System Performance Tests</a></li></ul></li><li class="inactive"><a href="/research/resources/glossary">Glossaries</a><ul><li class="inactive"><a href="/research/resources/glossary/cchhglossary">Climate Change and Human Health Glossary</a></li></ul></li><li class="inactive"><a href="/research/resources/imacs">International Myositis Assessment &amp; Clinical Studies Group (IMACS)</a><ul><li class="inactive"><a href="/research/resources/imacs/mentorship">About the IMACS Mentorship Program</a></li><li class="inactive"><a href="/research/resources/imacs/abouttools">About the Tools</a></li><li class="inactive"><a href="/research/resources/imacs/classificationcriteria">Classification Criteria</a></li><li class="inactive"><a href="/research/resources/imacs/committees">Committees and Scientific Interest Groups</a></li><li class="inactive"><a href="/research/resources/imacs/coordinators">Coordinators</a></li><li class="inactive"><a href="/research/resources/imacs/diseaseactivity">Disease Activity Core Set Measures</a></li><li class="inactive"><a href="/research/resources/imacs/diseasedamage">Disease Damage Core Set Measures</a></li><li class="inactive"><a href="/research/resources/imacs/imacsstudies">IMACS Studies</a></li><li class="inactive"><a href="/research/resources/imacs/membership">Membership</a><ul><li class="inactive"><a href="/research/resources/imacs/membership/imacshome">IMACS Member Home</a></li><li class="inactive"><a href="/research/resources/imacs/membership/membershipapp">Membership Application</a></li></ul></li><li class="inactive"><a href="/research/resources/imacs/response_criteria">Myositis Response Criteria</a></li><li class="inactive"><a href="/research/resources/imacs/othertools">Other Tools</a></li><li class="inactive"><a href="/research/resources/imacs/patientoutcome">Patient Reported Outcomes</a></li><li class="inactive"><a href="/research/resources/imacs/news_main">Program Updates</a><ul><li class="inactive"><a href="/research/resources/imacs/news_main/news_item06apr14">April 14, 2006: IMACS Joins the International Myositis Classification Criteria Project</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item2021apr2">April 2, 2021: Frederick W. Miller, M.D., Ph.D., Retirement</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item2021apr6">April 6, 2021: Global Genes RARE Champion of Hope Awards</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item05feb01">February 1, 2005: IMACS trial outcomes data repository in development</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item05feb18">February 18, 2005: The Rituximab In Myositis (RIM) Study</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item08jan16_1">January 16, 2008: Classification Criteria Project open for data collection</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item08jan16_2">January 16, 2008: IMACS Outcomes Repository Open for Trial/Study Submissions</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_itemdec10_1">January 7, 2011: Cure JM Wins Pepsi Challenge</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_itemsep10_1">January 7, 2011: TMA Opens Myositis Patient Registry</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item04jul01">July 1, 2004: Preliminary definitions of improvement for myositis published</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item2012jun26">June 1, 2012: Myositis Response Criteria to be Developed</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item05mar07">March 7, 2005: Investigative Opportunities in the RIM (Rituximab in Myositis) Study</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item2015may12">May 12, 2015: 1st International Myositis Conference</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item2017may5_8">May 5, 2017: 2nd Global Conference on Myositis</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item06oct18">October 18, 2006: IMACS Group Meeting 2006</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item08oct27">October 27, 2008: IMACS Group Meeting 2008</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item07oct28">October 28, 2007: IMACS Group Meeting 2007</a></li><li class="inactive"><a href="/research/resources/imacs/news_main/news_item05oct03">October 3, 2005: IMACS Annual Meeting 2005</a></li></ul></li><li class="inactive"><a href="/research/resources/imacs/imacspubs">Publications - IMACS</a></li><li class="inactive"><a href="/research/resources/imacs/relatedpubs">Publications - Related</a></li><li class="inactive"><a href="/research/resources/imacs/imacsforms">Registry Forms</a></li><li class="inactive"><a href="/research/resources/imacs/researchguidelines">Repository Use</a></li><li class="inactive"><a href="/research/resources/imacs/sponsors">Sponsors</a></li><li class="inactive"><a href="/research/resources/imacs/sites">Websites of Interest</a></li></ul></li><li class="inactive"><a href="/research/resources/library">Library &amp; Information Services</a><ul><li class="inactive"><a href="/research/resources/library/library_catalog">Library Catalog</a></li></ul></li><li class="inactive"><a href="/research/resources/protocols">Protocols</a><ul><li class="inactive"><a href="/research/resources/protocols/extraction">Extraction of High Quality RNA</a><ul><li class="inactive"><a href="/research/resources/protocols/extraction/disruption">Disruption and Homogenization of Tissue for the Extraction of RNA</a></li><li class="inactive"><a href="/research/resources/protocols/extraction/cleaning">Instrument Cleaning - Rnase Decontamination</a></li><li class="inactive"><a href="/research/resources/protocols/extraction/qiagen">RNA Isolation Using The Qiagen RNEasy Midi Kit</a></li><li class="inactive"><a href="/research/resources/protocols/extraction/picoscale">RNA Isolation from Pico-scale samples</a></li><li class="inactive"><a href="/research/resources/protocols/extraction/supplies">Supplies</a></li></ul></li><li class="inactive"><a href="/research/resources/protocols/protocols-immuno">Immunohistochemistry Protocols</a><ul><li class="inactive"><a href="/research/resources/protocols/protocols-immuno/reagents">Reagents</a></li><li class="inactive"><a href="/research/resources/protocols/protocols-immuno/retrievals">Retrievals</a></li></ul></li><li class="inactive"><a href="/research/resources/protocols/laser">Laser Microdissection</a><ul><li class="inactive"><a href="/research/resources/protocols/laser/embryo">Embryo Genotyping Protocol</a></li></ul></li></ul></li><li class="inactive"><a href="/research/resources/events">Seminars, Conferences, &amp; Symposia</a></li><li class="active ancestor"><a href="/research/resources/software">Software</a><ul class="open"><li class="inactive"><a 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href="/research/resources/software/biostatistics/ctrl-mom">Ctrl-Mom-Hybrid</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/epig-seq">EPIG-Seq</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/eagleview">EagleView</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/epicenter">EpiCenter</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/exp">Expression Predictor (ExP)</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/exp/quick-start">Expression Predictor Quick Start Guide</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/epig">Extracting Patterns and Identifying co-expressed Genes (EPIG)</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/epig/quick-start">Quick Start Guide</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/gaknn">GA/KNN</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/gaknn/gaknn-information">Variable Selection and Sample Classification Using a Genetic Algorithm and K-nearest Neighbors (GA/KNN) Method</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/gadem">GADEM</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/gei-trimm">GEI-TRIMM</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/gapwm">Genetic Algorithm Method for Optimizing a Position Weight Matrix</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/hillviewer">Hill Viewer</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/hybrid">Hybrid Design</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/iuta">Isoform Usage Two-step Analysis (IUTA)</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/lem_scripts">LEM Scripts Case-Sibling</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/lem">LEM Scripts</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/modk">Modk-Prototypes</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/omima">OMiMa</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/omima/instructions">OMiMa Instructions</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/omima/supplementary-material">OMiMa Supplementary Material</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/oriogen">ORIOGEN 4.01 - Order Restricted Inference for Ordered Gene Expression</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/orios">Order Restricted Inference for Oscillatory Systems (ORIOS) for Detecting Rhythmic Signals</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pvac">PCA-based Gene Filtering</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pcranalyzer">PCR Analyzer</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pixhap">PIX-HAP</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pixlrt">PIXLRT</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pspe">PSPE</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/page-software">Phase-shifted Analysis of Gene Expression (PAGE)</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/page/user-manual">PAGE User Manual</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/page/quick-start">Quick Start Guide for PAGE Software</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/phmm">Poisson Hidden Markov Model (PHMM)</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/pvca">Principal Variance Component Analysis</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/rscripts">R-SCRIPTS</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/r-code">R-code</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/r-code/how-to-use">How to Use R code for Fitting Random Periods Model</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/sa-modk">SA-Modk-Prototypes</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/sas">SAS Code to Fit Genetic Models</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/agnp">Silver Nano-particle Surface Coating and Gene Expression</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/sms">Sparse Multiclass SVM: Multiclass SVM with variable selection (SMS)</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/svn">Systematic Variation Normalization (SVN)</a><ul><li class="inactive"><a href="/research/resources/software/biostatistics/svn/start-guide">Systematic Variation Normalization Quick Start Guide</a></li></ul></li><li class="inactive"><a href="/research/resources/software/biostatistics/t-kde">T-KDE</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/trimmest">TRIMMEST</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/triad">TRlad Multi-Maker</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/comotif">coMotif</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/fdrMotif">fdrMotif</a></li><li class="inactive"><a href="/research/resources/software/biostatistics/gostag">goSTAG</a></li></ul></li><li class="inactive"><a href="/research/resources/software/epidemiology">Epidemiology</a><ul><li class="inactive"><a href="/research/resources/software/epidemiology/tagster">TAGster</a><ul><li class="inactive"><a href="/research/resources/software/epidemiology/tagster/algorithm">Algorithms Implemented in TAGster</a></li><li class="inactive"><a href="/research/resources/software/epidemiology/tagster/evaluation">Evaluation of the Algorithms Implemented in TAGster</a></li><li class="inactive"><a href="/research/resources/software/epidemiology/tagster/tutorial">TAGster Tutorial</a></li><li class="inactive"><a href="/research/resources/software/epidemiology/tagster/manual">User&#039;s Guide for TAGster</a></li></ul></li><li class="inactive"><a href="/research/resources/software/epidemiology/mpoptag">mPopTag</a><ul><li class="inactive"><a href="/research/resources/software/epidemiology/mpoptag/manual">User&#039;s Guide for mPopTag</a></li></ul></li></ul></li><li class="active ancestor"><a href="/research/resources/software/tox-pharm">Free Radical Metabolism</a><ul class="open"><li class="inactive"><a href="https://www.niehs.nih.gov/research/resources/software/tox-pharm/esdb/">Electron Spin Resonance Software Database</a></li><li class="active ancestor"><a href="/research/resources/software/tox-pharm/tools">Public Electron Paramagnetic Resonance Software Tools</a><ul class="open"><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/pgf">8-iso-PGF2α / PGF2α Ratio Tutorial and Software</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/dos">DOS Information</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/epr">EPR Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/er200">ER200 Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/ftepr">FT EPR Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/pest">PEST General Information Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/powfit">POWFIT HTML Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/scan">Scan Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/simepr">SimEPR Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/tune">Tune Manual</a></li><li class="active sibling"><a href="/research/resources/software/tox-pharm/tools/utilities">Utilities Manual</a></li><li class="this active open current"><span>WinSIM HTML Manual</span><a href="/research/resources/software/tox-pharm/tools/winsim" class="self is-active" id="mobileLink">WinSIM HTML Manual</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/resources/techtransfer">Technology Transfer</a><ul><li class="inactive"><a href="/research/resources/techtransfer/about">About Us</a><ul><li class="inactive"><a href="/research/resources/techtransfer/about/impact">Impact</a></li><li class="inactive"><a href="/research/resources/techtransfer/about/mission-vision-roles">OTT Mission, Vision, and Roles</a></li><li class="inactive"><a href="/research/resources/techtransfer/about/success-stories">Success Stories</a></li></ul></li><li class="inactive"><a href="/research/resources/techtransfer/information">For NIEHS Researchers</a><ul><li class="inactive"><a href="/research/resources/techtransfer/information/research-agreement">How to Get Started With a Research Agreement</a></li><li class="inactive"><a href="/research/resources/techtransfer/information/commercialization">Technology Commercialization Process</a></li></ul></li><li class="inactive"><a href="/research/resources/techtransfer/licensing">Licensing Opportunities</a></li><li class="inactive"><a href="/research/resources/techtransfer/partnering">Partnering With NIEHS</a><ul><li class="inactive"><a href="/research/resources/techtransfer/partnering/agreements">Types of Agreements</a></li></ul></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides">Training and Visual Guides</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath">Digitized Atlas of Mouse Liver Lesions</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/congenital">Congenital</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/congenital/ectopic">Ectopic Normal Kidney Tissue of the Liver</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/congenital/hepatodiaphragmatic">Hepatodiaphragmatic Nodule</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative">Degenerative</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/amyloid">Amyloid Deposition</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/bile_duct_cyst">Bile Duct Cyst</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/cystic_degeneration">Cystic Degeneration</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/fatty_change">Fatty Change</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/glycogen_deposition">Glycogen Deposition</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/hepatocyte">Hepatocyte Atrophy</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/hyaline_bodies">Hyaline Bodies</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/degenerative/hyaline_change">Hyaline Change</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder">Gallbladder</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/acute_inflammation">Acute Inflammation</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/chronic_inflammation">Chronic Inflammation</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/crystalline_inclusions">Crystalline Inclusions</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/cysts">Cysts</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/ectopic_pancreatic">Ectopic Pancreatic Acinar Tissue</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/edema">Edema</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/normal_gallbladder">Normal Gallbladder</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/papillary_adenoma">Papillary Adenoma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/gallbladder/papillary_hyperplasia">Papillary Hyperplasia</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast">Hyperplastic and Neoplastic</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/bile_duct_hyperplasia">Bile Duct Hyperplasia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/cholangiocarcinoma_hepatocholangiocarcinoma">Cholangiocarcinoma and Hepatocholangio-carcinoma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/cholangioma">Cholangioma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/endothelia_hyperplasia">Endothelial Hyperplasia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/erythroleukemia">Erythroleukemia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/foci_cellular_alteration">Foci of Cellular Alteration</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/foci_intravascular_hepatocytes">Foci of Intravascular Hepatocytes</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2">Hemangioma</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2/hemangioma_hemangiosarcoma">Hemangioma and Hemangiosarcoma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2/hepatoblastomas">Hepatoblastomas</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2/hepatocellular_adenomas">Hepatocellular Adenomas</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2/hepatocellular_carcinomas">Hepatocellular Carcinomas</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-2/histiocytic_sarcoma">Histiocytic Sarcoma</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3">Lipomatous Lesions</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3/kupffer_cell_hyperplasia">Kupffer Cell Hyperplasia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3/lipomatous_lesions">Lipomatous Lesions</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3/lymphoma">Lymphoma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3/malignant_melanoma">Malignant Melanoma</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-3/mast_cell_tumor">Mast Cell Tumor</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-4">Oval Cell Hyperplasia</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-4/hyperplasia">Hyperplasia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-4/ovarian_teratomas">Ovarian Teratomas</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/hyperplast/hyperplast-4/sarcoma">Sarcoma</a></li></ul></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous">Miscellaneous</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous/extramedullary_hematopoiesis">Extramedullary Hematopoiesis</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous/hepatocellular_hypertrophy">Hepatocellular Hypertrophy</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous/intrahepatocyte_erythrocytes">Intrahepatocyte Erythrocytes</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous/multinucleated_hepatocytes">Multinucleated Hepatocytes</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/miscellaneous/polyploidy">Polyploidy</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic">Necrotic, Inflammatory and Vascular</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic/angiectasis">Angiectasis</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic/apoptosis">Apoptosis</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic/helicobacter_hepaticus">Helicobacter Hepaticus</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic/inflammation_necrosis">Inflammation and Necrosis</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/necrotic/hepatitus_infection">Mouse Hepatitus Virus Infection</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal">Normal Liver</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal/gross">Gross</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal/immersion_non_fasted">Immersion Fixation in Non-Fasted Mouse Liver</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal/overnight_fast">Immersion Fixed Liver Following an Overnight Fast</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal/perfusion_non_fasted">Perfusion Fixation of the Lliver from a Non-Fasted Mouse</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/normal/polyploidy">Polyploidy in the Aged Mouse</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/toxicologic">Toxicologic</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/toxicologic/cholestasis">Cholestasis</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/toxicologic/hepatocyte_hypertrophy">Hepatocyte Hypertrophy</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/toxicologic/peroxisome_proliferation">Peroxisome Proliferation</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/toxicologic/toxic_change">Toxic Change</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique">Unique Lesions of Genetically Altered Mice</a><ul><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/transgenic">AL-TAg Transgenic</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/dual_transgenic">AL-TAg x AL-myc Dual Transgenic</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/bitransgenic">AL-ras x AL-myc Bitransgenic</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/transgenic_mice">Alb-uPA Transgenic Mice</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/erythroleukemia">Erythroleukemia</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/hepatitis_b">Hepatitis B Virus</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/myeloproliferative_syndrome">Myeloproliferative Syndrome</a></li><li class="inactive"><a href="/research/resources/visual-guides/liverpath/unique/alpha_transgenic">TGF Alpha Transgenic</a></li></ul></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training">Global Toxicologic Pathology Training Program</a><ul><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/tox-path">Global Toxicologic Pathology Training Program Training Modules</a><ul><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/tox-path/agent">Agent Based Training Modules</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/tox-path/practice">Practice Based Training Modules</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/tox-path/systems">Systems Based Training Modules</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/embryo-atlases">Mouse Embryo Atlases</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/nonneoplastic">Nonneoplastic Lesion Atlas and Nomenclature Resources</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/symposia">Satellite Symposia</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/techniques">Techniques in Toxicologic Pathology</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/resources">Toxicology and Pathology Career and Training Resources</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/publications">Toxicology and Pathology Publications</a></li><li class="inactive"><a href="/research/resources/visual-guides/dtt-training/societies">Toxicology, Pathology, and Laboratory Animal Medicine Societies and Organizations</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/embedding">Mouse &amp; Rat Embedding Suggestions</a><ul><li class="inactive"><a href="/research/resources/visual-guides/embedding/mouse">Mouse Embedding Suggestions</a></li><li class="inactive"><a href="/research/resources/visual-guides/embedding/rat">Rat Embedding Suggestions</a></li></ul></li><li class="inactive"><a href="/research/resources/visual-guides/guides">Revised Guides for Organ Sampling and Trimming in Rats and Mice</a><ul><li class="inactive"><a href="/research/resources/visual-guides/guides/kidneys">Adrenal and Kidney</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/brain-pituitary">Brain and Pituitary</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/female-repro">Female Reproductive System</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/gi-tract-sections">GI Tract</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/heart-sternum-diaphragm">Heart and Sternum</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/gross-trim-mouse">Intestine</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/livers">Liver</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/lungs">Lungs</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/male-repro">Male Reproductive and Urinary System</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/muscle-skin-bone">Musculoskeletal, Mammary Gland and Skin</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/l1-post">Nasal Cavity</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/spine">Spine</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/gi-stomach">Spleen and Stomach</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/thoracic-pluck-lungs">Thoracic Pluck, Lungs and Thymus</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/eye-lacrimal-tongue-zymbals">Tongue, Eye and Zymbal&#039;s</a></li><li class="inactive"><a href="/research/resources/visual-guides/guides/salivary-trachea">Trachea and Thyroid</a></li></ul></li></ul></li></ul></li><li class="inactive"><a href="/research/scientific-data">Scientific Data</a><ul><li class="inactive"><a href="/research/scientific-data/plan">Data Management and 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(FARE)</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/awards/mentor">Mentor of the Year</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/awards/misc">Miscellaneous Awards</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/awards/postbac-poster">NIH Postbac Poster Day Awards</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/awards/nih">NIH Summer Mentor Award</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/awards/science">Science Day Awards</a></li></ul></li><li class="inactive"><a href="/careers/research/fellows/involvement/committees">Committees</a><ul><li class="inactive"><a href="/careers/research/fellows/involvement/committees/planning">Career Symposium Planning Committee</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/committees/elite">ELITE Consortium</a></li><li class="inactive"><a 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href="/careers/research/fellows/involvement/events/symposium">Career Symposium</a><ul><li class="inactive"><a href="/careers/research/fellows/involvement/events/symposium/biomedical-career">Resources from the 23rd Annual NIEHS Biomedical Career Symposium</a></li></ul></li><li class="inactive"><a href="/careers/research/fellows/involvement/events/appreciation">Fellow Appreciation</a></li><li class="inactive"><a href="/careers/research/fellows/involvement/events/science-day">NIEHS Science Day</a></li></ul></li></ul></li><li class="inactive"><a href="/careers/research/fellows/alumni-outcomes">NIEHS Alumni Career Outcomes</a></li><li class="inactive"><a href="/careers/research/fellows/working">Working at NIEHS</a><ul><li class="inactive"><a href="/careers/research/fellows/working/benefits">Benefits</a><ul><li class="inactive"><a href="/careers/research/fellows/working/benefits/childcare">Childcare</a></li><li class="inactive"><a href="/careers/research/fellows/working/benefits/financial">Financial</a></li><li class="inactive"><a href="/careers/research/fellows/working/benefits/healthcare">Healthcare</a></li><li class="inactive"><a href="/careers/research/fellows/working/benefits/relocating">Relocating</a><ul><li class="inactive"><a href="/careers/research/fellows/working/benefits/relocating/moving-to-rtp">Moving to the RTP (Research Triangle Park) Area</a></li></ul></li><li class="inactive"><a href="/careers/research/fellows/working/benefits/salary">Stipend</a></li></ul></li><li class="inactive"><a href="/careers/research/fellows/working/policies">Policies and Guidelines</a><ul><li class="inactive"><a href="/careers/research/fellows/working/policies/maternity">Excused Leave</a></li><li class="inactive"><a href="/careers/research/fellows/working/policies/handbooks">Handbooks and Resources</a></li><li class="inactive"><a href="/careers/research/fellows/working/policies/outside">Outside Activities</a></li><li class="inactive"><a href="/careers/research/fellows/working/policies/rcr">Responsible Conduct of Research (RCR)</a></li><li class="inactive"><a href="/careers/research/fellows/working/policies/travel">Travel Policies</a></li><li class="inactive"><a href="/careers/research/fellows/working/policies/vacation">Vacation and Holiday</a></li></ul></li><li class="inactive"><a href="/careers/research/fellows/working/fellowships">Type of Fellowships</a><ul><li class="inactive"><a href="/careers/research/fellows/working/fellowships/graduate-students">Graduate Students</a></li><li class="inactive"><a href="/careers/research/fellows/working/fellowships/medical-students">Medical Students</a></li><li class="inactive"><a href="/careers/research/fellows/working/fellowships/postbacs">Postbaccalaureate Program</a></li><li class="inactive"><a href="/careers/research/fellows/working/fellowships/postdocs">Postdoctoral Program</a></li><li class="inactive"><a 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href="/careers/research/med-students/past-fellows/bob-sun">Bob Sun</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/chizoba-umesi">Chizoba Umesi</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/christian-hyacinthe">Christian Hyacinthe</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/dennis-akrobatu">Dennis Akrobatu</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/gordon-smilnak">Gordon Smilnak</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/michael-hu">Michael Hu</a></li><li class="inactive"><a href="/careers/research/med-students/past-fellows/teminioluwa-ajayi">Teminioluwa Ajayi</a></li></ul></li></ul></li><li class="inactive"><a href="/careers/research/summers">NIH Summer Internship Program</a><ul><li class="inactive"><a href="/careers/research/summers/process">Application Process</a></li><li class="inactive"><a 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<span class="jm-toc" tabindex="0">Table of Contents</span>
<ul style="display: none;">
<li><a href="#a3">This document's organization</a></li>
<li><a href="#a12">Introduction, Requirements, Installation</a></li>
<li><a href="#a14">Requirements</a></li>
<li><a href="#a21">Installation</a></li>
<li><a href="#a25">System Preferences</a></li>
<li><a href="#a49">Opening and Saving Data Files</a></li>
<li><a href="#a87">Spectrum Information</a></li>
<li><a href="#a91">Copying spectra to the Windows clipboard</a></li>
<li><a href="#a95">Controlling the Spectrum Display</a></li>
<li><a href="#a111">Spectrum Manipulations</a></li>
<li><a href="#a150">Introduction to EPR simulations</a></li>
<li><a href="#a267">Introduction to Optimizations</a></li>
<li><a href="#a277">Setting Optimizing Options</a></li>
<li><a href="#a278">Optimization options</a></li>
<li><a href="#a324">Starting an Interactive or Batch Optimization</a></li>
<li><a href="#a362">Reading Optimization Results</a></li>
<li><a href="#a383">Accessing Online Help Functions</a></li>
</ul>
</div>
<div>
<h3 id="a3">This document's organization</h3>
<p>This help file is organized in a tutorial manner to guide users through specific tasks, and does not specifically explain every detail of the program. Menu items are noted as <strong>choice:choice:choice</strong>; for instance, <strong>File:Open:Spectrum</strong> will indicate choose <strong>File</strong> then <strong>Open</strong> then <strong>Spectrum</strong>. Dialogue buttons are noted as enclosed in brackets, for instance <strong>[OK]</strong> indicates the OK button.</p>
<div class="slot-container" id="a36046" name="a36046">
<h3 id="a12">Introduction, Requirements, Installation</h3>
<p>PEST WinSIM is designed to compute the simulations of multiple species of isotropic EPR spectra. Up to 10 independent EPR signals each with up to 16 sets of hyper fine couplings can be calculated. Experimental spectra may be loaded for on-screen comparisons. A custom algorithm (LMB1) and the Simplex algorithm have been implemented to optimize the simulation to achieve the best possible fit with the experimental signal.</p>
<h3 id="a14">Requirements</h3>
<p>PEST WinSIM requires one of the following systems:</p>
<ul>
<li>Windows NT (intel only)</li>
<li>Windows 95</li>
<li>Windows 3.11 + Win32s libraries (not included with distribution)</li>
</ul>
<p>No additional memory or hard disk requirement is anticipated.</p>
<h3 id="a21">Installation</h3>
<p>Check the main <a href="/research/resources/software/tox-pharm/tools/pest" title="PEST General Information Manual">PEST documentation</a></p>
</div>
<div class="slot-container" id="a36048" name="a36048">
<h3 id="a25">System Preferences</h3>
<p>On start up, PEST WinSIM reads preferences from the niehs.ini file located in the Windows root directory. Other programs from the NIEHS may also access this file. Use <strong>Edit:Preferences</strong> to customize the program for your needs:</p>
<div class="back-to-page">← Back to Webpage</div>
<table class="pop_up_table" summary="Setting system preferences">
<tbody>
<tr>
<th width="20%">Start up Project</th>
<td width="80%">Defines default spectra and/or parameters to be opened when WinSIM is started if these options are selected. Click on <strong>[Save_now]</strong> to save the current spectra and/or parameters as defaults and <strong>[Open_now]</strong> to reload the default data.</td>
</tr>
<tr class="highlight">
<th width="20%">The Temp directory</th>
<td width="80%">Is the location for default data files for import/export exchange with the EPR.EXE program. This is normally C:\LAB\EPRDATA.</td>
</tr>
<tr>
<th width="20%">Help Browser</th>
<td width="80%">Refers to your WWW viewer, such as Netscape. Enter the full path so that WinSIM can start the browser for viewing help files and the Spin Trap Database.</td>
</tr>
<tr class="highlight">
<th width="20%">Help File</th>
<td width="80%">Refers to the HTML format help files that are part of the PEST distribution. A user may access them either over Internet directly from the NIEHS or install them onto her own hard disk. The current Internet address for these files was&nbsp;<em>http://alfred.niehs.nih.gov/LMB/pest/manual</em>. A typical hard disk address might be <em>c:\lab\docs\manual</em>. Since the first document is named <em>home.html</em>, a user only needs to enter the path of the directory.</td>
</tr>
</tbody>
</table>
</div>
<div class="slot-container" id="a36049" name="a36049">
<h3 id="a49">Opening and Saving Data Files</h3>
<p>The <strong>File:Open:Import</strong> function allows quick interchange with the DOS mode EPR.EXE program. The EPR.EXE program contains many more spectrum processing, measurement, and output options. Spectrum files are written to a temporary directory and located by number. For instance, in the DOS program, export the spectrum as #1, and in the WinSIM program import the same spectrum as #1. the user can also export from WinSIM and import into EPR.EXE.</p>
<p>The <strong>File:Open:Spectrum</strong> function is the primary means for loading new spectrum files into the program. The following types of files can be loaded.</p>
<ul>
<li>NIEHS binary from the PEST programs</li>
<li>spc/par from the Bruker OS/9 system</li>
<li>ASCII text columns</li>
</ul>
<p>A Dialogue box will prompt the user for the filename. By default, the spectrum will be loaded as the experimental continuous wave spectrum. However, the user may choose in the filename Dialogue box to load the spectrum as either FT Real, FT Imaginary, or CW simulation</p>
<p>The <strong>File:Open:Project</strong> function groups spectrum and parameter files together with a single base filename. This allows the user to save and recall an experimental spectrum, the simulated spectrum, and the parameters at once. Filename extensions are used to denote the different types of data:</p>
<table class="text-to-top" summary="Opening and saving data files">
<tbody>
<tr>
<th scope="row" width="60">.lmb ----</th>
<td>experimental spectrum file (NIEHS binary format only)</td>
</tr>
<tr class="highlight">
<th scope="row">.sim ----</th>
<td>simulated spectrum file (NIEHS binary format only)</td>
</tr>
<tr>
<th scope="row">.out ----</th>
<td>ASCII version of parameters file, calculated parameters only</td>
</tr>
<tr class="highlight">
<th scope="row">.epr ----</th>
<td>ASCII printout file of simulation parameters</td>
</tr>
<tr>
<th scope="row">.sdx ----</th>
<td>parameters file including all parameters</td>
</tr>
</tbody>
</table>
<p>By default, only the .lmb, .sim, and .sdx files are saved and opened. The user can select any set of these files to open and save. Therefore, the user can choose to load only the parameters from a project, for instance. Note that the extensions cannot be changed.</p>
<p>Chose <strong>File:New</strong> to erase the current spectrum data. This will not affect the current simulation parameters.</p>
<p><strong>File saving</strong> works the same as file opening. If a spectrum file is opened, the current simulation parameters are not disturbed. If simulation parameters are opened, the current spectrum data is not disturbed.</p>
<div class="center caption " style="max-width:371px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="371" style="max-width: 371px;width: 100%;" src="/sites/default/files/research/resources/assets/images/fileopengif.gif" alt="File Open">
</div>
<br class="clear-left">
&nbsp;</div>
<div class="slot-container" id="a36053" name="a36053">
<h3 id="a87">Spectrum Information</h3>
<p>Once a spectrum is opened, choose <strong>Edit:Information</strong> to check the number of data points, scan range and field center, and other instrumental parameters.</p>
</div>
<div class="slot-container" id="a36056" name="a36056">
<h3 id="a91">Copying spectra to the Windows clipboard</h3>
<p>PEST WinSIM will copy data to the Windows clipboard, which the user may employ to paste the data into a spreadsheet style program such as Microcal Origin or Microsoft Excel for custom manipulations. Choose <strong>Edit:Copy_data</strong> and the current spectra displayed will be formatted into multiple data columns for pasting into a spreadsheet control. Pasting from the clipboard into the spectra arrays is not supported.</p>
</div>
<div class="slot-container" id="a36059" name="a36059">
<h3 id="a95">Controlling the Spectrum Display</h3>
<p>The user may refresh the screen display with the <strong>Display:Plot</strong> command. Use <strong>Display:Rescale</strong> to automatically scale a spectrum plot which is too large or too small for the display area. Use <strong>Display:Overlay</strong> to switch between plotting multiple spectra as overlapped or separate lines.</p>
<p>Select <strong>Display:Display</strong> to further control the spectrum screen plotting. A dialogue box appears with entries for the left, right, bottom, and top values of the plotting area ; selections for which spectrum data to plot ; whether or not to overlay the plots ; and to show the x and y axis. To <strong>zoom</strong> into or out-of the plot, click on the arrow buttons <strong>[<big>&lt;</big>][<big>&gt;</big>]</strong>and switch between scale movements or position movements. The X scale is shown as datapoints and the Y scale is shown as program plotting units; the default Y scale is the same as the DOS EPR.EXE program (+/- 500).</p>
<div class="center caption " style="max-width:234px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="234" style="max-width: 234px;width: 100%;" src="/sites/default/files/research/resources/assets/images/displaygif.gif" alt="Display">
</div>
<br class="clear-left">
&nbsp;</div>
<div class="slot-container" id="a36072" name="a36072">
<h3 id="a111">Spectrum Manipulations</h3>
<h4 id="a112">Controlling the spectrum display</h4>
<p>Spectra may be <strong>filtered</strong> by selecting <strong>Manipulations:Filter</strong>. The experimental spectrum will undergo an <strong>FFT</strong> to separate its frequency components and the Real and <em>Imaginary</em> domains will be displayed. The FFT is a display of the magnitudes of the fourier frequencies in the data. Therefore, if you zero the lowest FFT data points, you will filter out low frequency information such as a slowly rolling baseline. If you zero the highest FFT data points, you will filter out high frequency noise in your spectrum. A dialogue box prompts the user for the starting and stopping filter points. The suggested High Filter value is the point at which the FFT signal has decreased to 0.025 (1/40) of its highest value. The FFT spectra are displayed with this value as the middle point of the X domain. For instance, if the 0.025 point occurs at FFT datapoint 98, then the X domain of the display will be from 0 to 196. This value is only a guess at a good point for filtering, the user may want to change it based on the display. If it appears that significant signals exist beyond that point, the user should enter a higher value. FFT datapoints above (to the right) of the High_Filter will be zeroed, and FFT datapoints below (to the left) of the Low_filter will be zeroed. Once you have verified the filter points, click on the <strong>High_Filter</strong> and/or <strong>Low_Filter</strong> buttons to actually zero out those FFT datapoints. Then select <strong>Keep</strong> compute the inverse FFT and receive the filtered spectrum; or select <strong>Discard</strong> to return to the un-filtered spectrum. Once a spectrum has been filtered, it must be re-opened from disk to go back to the original data.</p>
<p>The following display shows a spectrum before and after filtering:</p>
<div class="center caption " style="max-width:450px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="450" style="max-width: 450px;width: 100%;" src="/sites/default/files/research/resources/assets/images/filtergif.gif" alt="Filter">
</div>
&nbsp;
<h4 id="a127">Speeding simulations by combining FFT Real &amp; Imaginary</h4>
<p><strong>Simulation speed is improved</strong> by calculating only the FFT signal and thus not computing the inverse FFT. To compare with the experimental, we must first create the FFT of the experimental spectrum. Because the FFT has both Real and Imaginary domains, we then have two signals to display. However, only the first half of the FFT datapoints are meaningful, the Nicest theorem. Therefore, we can display the FFT signal as a combination of the Real and Imagines by just tacking on the Real component onto the end of the Imaginary. As with the filtering, we can discard frequencies that have insignificant intensity. When a user chooses <strong>Manipulations:Combine_FFT</strong>, the FFT of the experimental spectrum is computed and the Real and Imaginary domains are displayed. As with the filter function, the 0.025 (1/40th) intensity is chosen as a like combination point; although, the user may input another value. Once the user accepts a value, the experimental spectrum will be represented by the significant portion of the Imaginary domain on the left and the same size portion of the Real domain on the right:</p>
<div class="center caption " style="max-width:450px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="450" style="max-width: 450px;width: 100%;" src="/sites/default/files/research/resources/assets/images/combinegif.gif" alt="Ccombine">
</div>
&nbsp;
<h4 id="a135">Accessing FFT data directly</h4>
<p>The forward and inverse <strong>FFT of the experimental</strong> can be computed using <strong>Manipulations:exp_&gt;&gt;_FFT</strong> and <strong>Manipulations:exp_&lt;&lt;_FFT</strong> respectively. The display will switch appropriately.</p>
<p>If you use <strong>external programs</strong> to process FFT data you can save and load those datasets independently using the <strong>Manipulations:Controls</strong> selection which brings up a dialogue box with controls for <strong>transferring datasets</strong> and executing forward and inverse <strong>FFT</strong> computations directly.</p>
<div class="center caption " style="max-width:323px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="323" style="max-width: 323px;width: 100%;" src="/sites/default/files/research/resources/assets/images/fftcntrlgif.gif" alt="FFT Manipulations">
</div>
<br class="clear-left">
&nbsp;</div>
<div class="slot-container" id="a36123" name="a36123">
<h3 id="a150">Introduction to EPR simulations</h3>
<h4 id="a151">Simulating spectra</h4>
<p>The most definitive means of identifying a free radical species is to compute a successful simulation and assign the hyperfine parameters to structural members. The most important function of this program is to assist the user in that process. This program is specialized to compute the simulations of multiple species of freely rotating isotropic free radicals, such as found in complex biochemical spin trap systems. PEST WinSIM has the following capabilities:</p>
<ul>
<li>Computes up to 10 species of free radicals.</li>
<li>Computes up to 16 hyperfine nuclei sites per species. Each site may have an unlimited number of equivalent nuclei.</li>
<li>First order FFT based computations.</li>
<li>Approximates the M(I) dependent linewidths of motionally restricted nitroxide radicals, assigning independent linewidths to the -1,0,+1 line positions.</li>
<li>Approximates the effects of Time Constant and Modulation Amplitude.</li>
<li>Adjustable mix of Lorenztian and Gaussian lineshapes.</li>
<li>Optimizes any/all simulation parameters via:
<ul>
<li>LMB1 algorithm (published in J.M.R.)</li>
<li>Simplex algorithm</li>
</ul>
</li>
<li>Any parameter may be excluded from optimization.</li>
<li>Variable limits on parameter adjustment during optimization.</li>
<li>Graphically interactive and batch mode Optimization.</li>
<li>Optimization reports generated.</li>
</ul>
<h4 id="a168">Setting instrument and global spectral parameters</h4>
<p>Choose <strong>Simulation:Scan_info</strong> to enter consequential instrumental parameters :</p>
<ul>
<li>Field Center (G)</li>
<li>Scan Range (G)</li>
<li>Modulation amplitude (G)</li>
<li>Time Constant (TC)</li>
<li>Harmonic ( 0th, 1st, 2nd )</li>
<li>CW or FFT</li>
<li>Simple isotropic or M(I) dependent nitroxide</li>
</ul>
<p>To skip the Mod.Amp. and Time Constant computations, enter zero for their values. Note that that the Time Constant is expressed as the ratio which is generally in the range of 0.1 to 1.0 for most CW scans :</p>
<p>TC = Time Constant (ms) / Scan Time (s)</p>
<h4 id="a181">Setting hyper fine coupling, relative area, and line shape values</h4>
<p>Choose <strong>Simulation:Parameters</strong> to edit the hyperfine, relative area, and lineshape parameters. A LARGE dialogue box appears with several input fields:</p>
<ul>
<li><strong>Previous] [Next]</strong> : use these buttons to skip to another radical species.</li>
<li><strong>Calculate this species</strong> : choose whether or not to include each species in the simulation. Note that if no species are computed, a single line should result.</li>
<li><strong>Area</strong> : the relative spectral area of each species. For single species this data is not used. All simulations are computed with the same maximum peak height as the experimental spectrum if one is present.</li>
<li><strong>g-shift</strong> : the relative shift in gauss of the center of the spectrum (in G) from field center. This is used to move the spectrum in the magnetic field domain. I used this method since this value is more straightforward to estimate than g-value.</li>
<li><strong>Lineshape</strong> : the percentage of the spectrum that has Lorentzian shape. A pure lorentzian line would be 100%. A pure Gaussian line would be 0%.</li>
<li><strong>Simple LW</strong> : the linewidth used when computing single linewidth spectra. If nitroxide simulation is chosen, then this value is not used.</li>
<li><strong>Nitroxide</strong> : If nitroxide simulation is chosen, then these values are used in the computation:
<table class="text-to-top" style="width: 403px;" summary="Nitroxide">
<tbody>
<tr>
<th scope="row" style="width: 112px;" width="70">Hyperfine:</th>
<td style="width: 289px;">coupling from the principal nitrogen nuclei.</td>
</tr>
<tr class="highlight">
<th scope="row" style="width: 112px;">LW -1:</th>
<td style="width: 289px;">the low field component linewidth</td>
</tr>
<tr>
<th scope="row" style="width: 112px;">LW 0 :</th>
<td style="width: 289px;">the middle field component linewidth</td>
</tr>
<tr class="highlight">
<th scope="row" style="width: 112px;">LW +1 :</th>
<td style="width: 289px;">the high field component linewidth</td>
</tr>
</tbody>
</table>
</li>
</ul>
<p class="top"><a href="#top">&nbsp; Back to top</a></p>
<p>Each of these fields has a checkbox <strong>[x]</strong> in the <strong>Opt</strong> column for selecting if that parameter is to be adjusted during optimization. To exclude a parameter from optimization ( ie.. fix the value as constant ), make this selection unchecked.</p>
<p>Then enter the <strong>hyperfine coupling</strong> parameters as in this example :</p>
<table class="text-to-top" summary="hyperfine coupling parameters">
<tbody>
<tr>
<th scope="col" width="50">Set</th>
<th scope="col">Hyperfine</th>
<th scope="col">Spin</th>
<th scope="col">Number</th>
<th scope="col">Opt</th>
</tr>
<tr>
<td><strong>[x] 1</strong></td>
<td>14.0</td>
<td>1.0</td>
<td>1</td>
<td>[x]</td>
</tr>
<tr class="highlight">
<td><strong>[x] 2</strong></td>
<td>16.2</td>
<td>0.5</td>
<td>1</td>
<td>[x]</td>
</tr>
<tr>
<td><strong>[x] 3</strong></td>
<td>2.2</td>
<td>0.5</td>
<td>3</td>
<td>[&nbsp; ]</td>
</tr>
<tr class="highlight">
<td><strong>[ &nbsp; ] 4</strong></td>
<td>2.2</td>
<td>1.0</td>
<td>2</td>
<td>[&nbsp; ]</td>
</tr>
</tbody>
</table>
<p>The simulation will be computed with a spin=1 and coupling=14.0G nucleus ; a spin=1/2 and coupling=16.2 G nucleus ; and a spin=1/2 and coupling=2.2 G on three nuclei ( producing the 1-3-3-1 pattern of a methyl group ). Set #4, with a spin=1.0 and coupling=2.2 on two nuclei is not computed since the leading checkbox is not selected. The <strong>Opt</strong> field is used to indicate if that parameter should be adjusted during the optimization, in this example only the first two hyperfine will be adjusted during optimization. The user could easily switch off Set #3 and switch on Set #4 to alternate hypothesis about the radical structure.</p>
<p>Now select <strong>[Simulate]</strong> (or press Enter) to compute the simulation. The simulated spectrum will be plotted on the screen along with the experimental. (if there is an experimental spectrum loaded) The Simulation Parameters dialogue box will stay on the screen, the user can close the box or just move it to the side of the screen. This allows quick cycling of changing parameters - computing spectrum - viewing results.</p>
<h4 id="a258">Computing the correlation value and residual spectrum</h4>
<p>Choose <strong>Simulation:Correlation</strong> to compute the Spearman's Rank Correlation Coefficient between the current experimental and simulated spectra. The value shows up on the status bar at the bottom of the PEST WinSIM window. Choose <strong>Simulation:Residual</strong> to subtract the simulated spectrum from the experimental spectrum. Choose it again to quickly return to the simulated spectrum.</p>
<div class="center caption " style="max-width:450px; width:100%;">
<img class="media media--type-image media--view-mode-default" data-hide-caption="0" data-hide-print="0" data-hide-small="0" data-no-border="0" data-percent="0" data-width="450" style="max-width: 450px;width: 100%;" src="/sites/default/files/research/resources/assets/images/simpargif.gif" alt="Simulated spectrum">
</div>
<br class="clear-left">
&nbsp;</div>
<div class="slot-container" id="a36266" name="a36266">
<h3 id="a267">Introduction to Optimizations</h3>
<p>PEST WinSIM will adjust the values of the simulation parameters to create the best fit between simulated and experimental spectra. This is an iterative process consisting of guess adjustments, trial computations, and error computation. In general, EPR spectra are overdetermined, that is, more than one set of simulation parameters will produce an apparently good fit to the experimental spectrum. Therefore, any optimization algorithm must rigorously check the error space for local minima in the error estimation to produce a robust result. Two algorithms have been implemented: <strong>LMB1</strong> was developed by Dave Duling as an extension and derivation of the TUNE algorithm of Ann Motten and Joerg Schreiber and was published in J.M.R. The well known <strong>Simplex</strong> algorithm is also available. References for both methods may be found in the <a href="/research/resources/software/tox-pharm/tools/pest#references" title="PEST General Information Manual">PEST manual reference section</a>.</p>
<p>Select <strong>Simulations:Optimize</strong> to initiate the process. Choose the algorithm you will use and <strong>[Setup]</strong> to change the default optimization. Choose <strong>Constraints</strong> to set boundaries on how far certain parameters my deviate from their initial values.</p>
</div>
<div class="slot-container" id="a36267" name="a36267">
<h3 id="a277">Setting Optimizing Options</h3>
<h3 id="a278">Optimization options</h3>
<ul>
<li>
<h4 id="a276">LMB1 setup</h4>
<table class="text-to-top" summary="LMB1 setup">
<tbody>
<tr>
<th width="20%">Hyperfine analysis:</th>
<td width="80%"><strong>Two options are available:</strong>
<ul>
<li><strong>Non-parametric</strong> : hyperfine values are adjusted independently</li>
<li><strong>Parametric</strong> : hyperfine values are adjusted such that the sum of splitting values multiplied by twice the spin multiplied by the number of nuclei is constant. The keeps the total spectral width constant. Use this when you are certain of the end lines.</li>
</ul>
</td>
</tr>
<tr class="highlight">
<th width="20%">Parameter descent gradient:</th>
<td width="80%">Initially, the simulation parameters are adjusted in large increments and then increment size is decreased to digital resolution in finite steps. This value controls the curvature of the descent. The default value is <strong>binary</strong> which is the steepest descent. <strong>Quadratic</strong> and <strong>linear</strong> descents are much less steep and thus consume much more time but are somewhat less likely to miss important minima in the error domain.</td>
</tr>
<tr>
<th width="20%">Levels of granularity:</th>
<td width="80%">This controls the number of steps in the parameter descent curve. The steeper the descent, the smaller this value should be. For instance, the default value for binary gradient is 7, while corresponding value for linear would be 2^7=128.</td>
</tr>
</tbody>
</table>
</li>
<li>
<h4 id="a298">Simplex setup</h4>
<table class="text-to-top" summary="Simplex setup">
<tbody>
<tr>
<th width="20%">Number of restarts:</th>
<td width="80%">controls the number of times the algorithm will restart once it has reached an error minimum.</td>
</tr>
<tr class="highlight">
<th width="20%">Max. iterations per restart:</th>
<td width="80%">this puts a limit on the number of trial simulations that will be computed, keeping the program from wandering endlessly when it has an obviously wrong set of parameters.</td>
</tr>
<tr>
<th width="20%">Fractional tolerance:</th>
<td width="80%">Simplex stops when the slope of the imaginary line connecting the lowest errors thus far achieved is below a certain value. This tells the algorithm when to terminate within a minima.</td>
</tr>
</tbody>
</table>
</li>
<li>
<h4 id="a311">Constraints</h4>
<p>Used to limit the range of parameter deviation. To simplify the selection process, WinSIM implements constraints for the major classes of parameters: Hyperfines, g-positions, Linewidths, and relative Intensity. Enter a percentage value for the amount of deviation from the original value and use the checkbox <strong>[x]</strong> to enable or disable these constraints. <em>Constraints are only enabled for the LMB1 algorithm</em>.</p>
</li>
<li>
<h4 id="a316">Data point range</h4>
<p>Use this to limit the range of the scan that is used in the error computation, for instance when an unidentified signal grows during the scan to dominate the high field area ; when the main signal just decays very rapidly ; or when a bad baseline effect is visible in the wings.</p>
</li>
</ul>
</div>
<div class="slot-container" id="a36269" name="a36269">
<h3 id="a324">Starting an Interactive or Batch Optimization</h3>
<p>WinSIM may start either a <em>interactive</em> or batch mode optimization. Interactive Optimization run in the WinSIM window and present continuous updates of the simulation plot and error statistics. Batch mode Optimization run as a separate TUNE process whose results can only be viewed after the process has completed. However, several TUNE processes can be run concurrently and these processes may be run on other computers on the network.</p>
<p>Select <strong>[ GO ]</strong> to start the optimization as an <em>interactive process</em>. The plot of the simulation and experimental spectra will update on a timely basis and the status bar will show the current status of the optimization with the following information:</p>
<ul>
<li>Algorithm used: LMB1 or Simplex</li>
<li>Starting error ( sum of squared residuals )</li>
<li>Current error</li>
<li>Number of simulations ( n )<br>
&nbsp; - and -</li>
<li>Level : LMB1 parameter for the current step, see levels of granularity above; this value will decrement to one. If this value seems to never change, it may indicate that the initial parameters are in error, which would be obvious by the simulation plot.</li>
<li>Species, Par : LMB1 parameters for the current species and parameter being optimized. This is mostly for internal use as a programmer's diagnostic.<br>
&nbsp; - or -</li>
<li>Restart : SIMPLEX restart value, this value will increment to the number of simplex restarts, see above.</li>
</ul>
<p>Select <strong>[ TUNE ]</strong> to start a batch mode optimization. This will run the <strong>Tune</strong> program as a separate process; therefore, you may run several TUNE program Optimization concurrently to test different hypothesis or to test one hypothesis on several sets of data. WinSIM will present a dialogue box with these options:</p>
<table class="text-to-top" summary="options">
<tbody>
<tr>
<th width="20%">Format:</th>
<td width="80%">choose NIEHS binary or ASCII format data files. If the TUNE will be run on your Windows PC computer, choose binary. If you intend to run TUNE on a UNIX computer, choose ASCII.</td>
</tr>
<tr class="highlight">
<th width="20%">Filename:</th>
<td width="80%">TUNE requires input files to execute; WinSIM will write out the required TUNE files automatically. By default, the current filename with an underscore prepended will be used. The user may enter a different filename if needed. The files will be written into the current directory.</td>
</tr>
<tr>
<th width="20%">[ Start Now ]:</th>
<td width="80%">Choose this to initiate the TUNE process. First the necessary files will be written, then TUNE will be started as a separate process. The directory containing the TUNE binary (tune.exe) must be in the current system PATH (this is usually c:\lab).</td>
</tr>
<tr class="highlight">
<th width="20%">[ Save files ]:</th>
<td width="80%">Choose this to only save the necessary TUNE files but not start the TUNE process, for instance, when the TUNE is going to be run on a UNIX computer.</td>
</tr>
<tr>
<th width="20%">[ Read results ]:</th>
<td width="80%">Choose this to read in the TUNE results once a TUNE has completed. The files associated with the above displayed filename will be read. The simulation spectrum is not read automatically, but can be easily calculated with a <strong>Simulation:Simulate</strong> selection.</td>
</tr>
</tbody>
</table>
</div>
<div class="slot-container" id="a36271" name="a36271">
<h3 id="a362">Reading Optimization Results</h3>
<p>The optimization results are written in three places, depending on whether the process is run <em>interactively</em> or in <em>batch</em> mode.</p>
<table class="text-to-top" summary="Optimization Results">
<tbody>
<tr>
<th width="20%">Printout file:</th>
<td width="80%">A printout file is created containing the final parameters and error statistics in a readable and printable ASCII form. For interactive Optimization, the Notepad program is launched with this information. For batch Optimization, a file is written with a <strong>.epr</strong> extension, if you read in the TUNE results through the TUNE dialogue box, this file will be loaded into a new instance of Notepad.</td>
</tr>
<tr class="highlight">
<th width="20%">Parameter file:</th>
<td width="80%">A parameter file is created containing the final parameters in the TUNE input format which can be read by TUNE or WinSIM. This file has the .par extension. Only the batch mode TUNE program produces this file at the end of an optimization; however, WinSIM can produce this file through the <strong>File:Save:Project</strong> options.</td>
</tr>
<tr>
<th width="20%">Simulated spectrum:</th>
<td width="80%">A simulated spectrum file is created by the batch mode TUNE program; however, WinSIM can produce this file through the <strong>File:Save:Project</strong> options. This file has the <strong>.sim</strong> extension if it is a NIEHS binary file or the <strong>.dat</strong> extension if it is an ASCII file.</td>
</tr>
</tbody>
</table>
</div>
<div class="slot-container" id="a36272" name="a36272">
<h3 id="a383">Accessing Online Help Functions</h3>
<p>Select <strong>Help</strong>:</p>
<table class="text-to-top" summary="Online help">
<tbody>
<tr>
<th width="20%">Index</th>
<td width="80%">To view this help file.<br>
The <strong>Edit:Preferences</strong> must be correctly entered and saved.</td>
</tr>
<tr class="highlight">
<th width="20%">Database</th>
<td width="80%">To access the online Spin Trap Data Base (STDB).<br>
The <strong>Edit:Preferences</strong> must be correctly entered and saved.</td>
</tr>
<tr>
<th width="20%">About</th>
<td width="80%">To view information about the author of this program and the revision being used.</td>
</tr>
</tbody>
</table>
</div>
</div>
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