780 lines
30 KiB
Text
780 lines
30 KiB
Text
|
||
<!DOCTYPE html>
|
||
<html lang="es" dir="ltr">
|
||
<head>
|
||
<meta charset="utf-8" />
|
||
<meta name="description" content="Uveitis causes inflammation inside the eye and is a cause of vision loss in the US. Clinical studies funded by NEI provide people the information they need to make informed health care decisions about their eyes." />
|
||
<meta name="google" content="vityevxlt8UuVFWvgz9_YwmJ5F0Nby_B3t54LLh-3Zw,lACaj571Gx_VdLF3HKSKUf1Wxx0H_bWxO3BYDZ_C1uw" />
|
||
<meta name="google-site-verification" content="vityevxlt8UuVFWvgz9_YwmJ5F0Nby_B3t54LLh-3Zw" />
|
||
<meta name="google-site-verification" content="lACaj571Gx_VdLF3HKSKUf1Wxx0H_bWxO3BYDZ_C1uw" />
|
||
<meta name="google-site-verification" content="UDfyeEAWNX_rJUHwog9j1kziEnByGwhkSJGLJclUWDA" />
|
||
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
||
<script type="application/ld+json">{
|
||
"@context": "https://schema.org",
|
||
"@graph": [
|
||
{
|
||
"@type": "WebPage",
|
||
"@id": "https://www.nei.nih.gov/research/clinical-trials/landmark-clinical-vision-and-eye-research/uveitis-research",
|
||
"breadcrumb": {
|
||
"@type": "BreadcrumbList",
|
||
"itemListElement": [
|
||
{
|
||
"@type": "ListItem",
|
||
"position": 1,
|
||
"name": "Home",
|
||
"item": "https://www.nei.nih.gov/espanol"
|
||
},
|
||
{
|
||
"@type": "ListItem",
|
||
"position": 2,
|
||
"name": "Uveitis Research ",
|
||
"item": "https://www.nei.nih.gov/espanol/node/3904"
|
||
}
|
||
]
|
||
},
|
||
"author": {
|
||
"@type": "GovernmentOrganization",
|
||
"@id": "https://www.nei.nih.gov",
|
||
"name": "National Eye Institute",
|
||
"url": "https://www.nei.nih.gov"
|
||
},
|
||
"publisher": {
|
||
"@type": "GovernmentOrganization",
|
||
"@id": "https://www.nei.nih.gov",
|
||
"name": "National Eye Institute",
|
||
"url": "https://www.nei.nih.gov"
|
||
}
|
||
}
|
||
]
|
||
}</script>
|
||
<link rel="icon" type="image/png" href="/themes/custom/nei/images/favicon.png" />
|
||
<link rel="apple-touch-icon" href="/themes/custom/nei/images/apple-touch-icon.png" />
|
||
<meta name="last-updated" content="Aug 14, 2023, 10:43:16 AM" />
|
||
<link rel="icon" href="/themes/custom/nei/favicon.ico" type="image/vnd.microsoft.icon" />
|
||
<link rel="alternate" hreflang="en" href="https://www.nei.nih.gov/research/clinical-trials/landmark-clinical-vision-and-eye-research/uveitis-research" />
|
||
<link rel="canonical" href="https://www.nei.nih.gov/research/clinical-trials/landmark-clinical-vision-and-eye-research/uveitis-research" />
|
||
<link rel="shortlink" href="https://www.nei.nih.gov/node/3904" />
|
||
|
||
<title>Uveitis Research</title>
|
||
<link rel="preload" href="/themes/custom/nei/fonts/Aleo-Bold.woff2" as="font" type="font/woff2" crossorigin>
|
||
<link rel="preload" href="/themes/custom/nei/fonts/Lato-Regular.woff2" as="font" type="font/woff2" crossorigin>
|
||
<link rel="stylesheet" media="all" href="/sites/default/files/css/css_PGSk_7b88hq2qr_--_38MLvoj1ffr9jv3JhnNJTnKUM.css?delta=0&language=es&theme=nei&include=eJw1ytEKgCAMRuEXsnwk-dMxrOliTqi3j4iuDnycfFCprpbyHK4tDb-FRvwSshrFYvOErNhxBUHnCaYEcbJ_61Qji26Q5ZXa-QH_YCJ9" />
|
||
<link rel="stylesheet" media="all" href="/themes/custom/nei/css/style.css?sraguf" />
|
||
|
||
<script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"espanol\/","currentPath":"node\/3904","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"es"},"pluralDelimiter":"\u0003","gtag":{"tagId":"","consentMode":false,"otherIds":[],"events":[],"additionalConfigInfo":[]},"suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJxdjFsOwjAMBC8U6iNFbmKZgPNQ7BTK6SmgCsrPrndkTbhSTFa7D0OtZq-2Cil8yoWOj5WYYT8c18pC3pCBt_jfE17wfoTZCRYeyORRjPruLmhpIS-b2EvFmArD73CFErDUGeWkoadmekCb5fXVsCN3bGeF2EdDmb5kGqWNWZKeKTpd1SjDjEpuSXRTeOeUaxxCT9WYZ50","theme":"nei","theme_token":null},"ajaxTrustedUrl":{"form_action_p_pvdeGsVG5zNF_XLGPTvYSKCf43t8qZYSwcfZl2uzM":true},"gtm":{"tagId":null,"settings":{"data_layer":"dataLayer","include_classes":false,"allowlist_classes":"google\nnonGooglePixels\nnonGoogleScripts\nnonGoogleIframes","blocklist_classes":"customScripts\ncustomPixels","include_environment":false,"environment_id":"","environment_token":""},"tagIds":["GTM-TLVNS7W"]},"user":{"uid":0,"permissionsHash":"c48594e108b5c1c2bea409821b71477d5bc2724c8cae6d31f1d985af0daab85c"}}</script>
|
||
<script src="/sites/default/files/js/js_WgzMsgqb-MiW-Z2aLffGQHepZwX2hWrEHSrb46WqZrk.js?scope=header&delta=0&language=es&theme=nei&include=eJxdjEEOgCAMBD-E9kmkYrOpqdQAMerr5eBBvUx29jCp8HUKQOkZAe4wiY1B6Pj7yAsf33MNmZvuEq0nojnPmkFvCVmUYD6xDTUV3Vq9ATUbLxk"></script>
|
||
<script src="https://script.crazyegg.com/pages/scripts/0117/6571.js" async></script>
|
||
<script src="/modules/contrib/google_tag/js/gtag.js?sraguf"></script>
|
||
<script src="/modules/contrib/google_tag/js/gtm.js?sraguf"></script>
|
||
|
||
</head>
|
||
<body class="t-page t-node__3904 path-node-3904">
|
||
<a href="#main-content" class="u-skip-link">
|
||
Skip to content
|
||
</a>
|
||
<noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-TLVNS7W"
|
||
height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
|
||
|
||
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
|
||
|
||
<div id="u-page-outer" class="u-outer">
|
||
<div class="views-element-container site-notice-block" id="block-views-block-site-notices-block-1">
|
||
|
||
|
||
|
||
|
||
|
||
<div>
|
||
<div class="js-view-dom-id-0ad8bc2e426a8b1cafef8a2990c96d7d973a7a2e7a770918fcf24ec9352cfecc site-notices">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<img src="/themes/custom/nei/images/NEI-logo-tagline.svg" alt="" width="200" height="48" class="u-print-only">
|
||
<div class="r-global-header">
|
||
<div id="r-header-outer" class="r-header">
|
||
|
||
<div class="r-header-inner">
|
||
|
||
<div id="block-nei-branding" class="o-block--logo" role="banner">
|
||
|
||
|
||
|
||
|
||
|
||
<div class="o-logo">
|
||
<a href="/espanol" class="o-logo__link" title="Home" rel="home"><span class="o-logo__text">National Eye Institute</span> <span class="o-logo__tagline">Research Today… Vision Tomorrow</span></a>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
<div id="block-neimenubutton-2">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="o-menu-toggle"><button class="o-menu-toggle__btn" id="menu-toggle__btn" aria-controls="block-mainnavigation" aria-expanded="true">Menú</button></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="language-switcher-language-url has-no-translation" id="block-languageswitcher" role="navigation" aria-label="Language switcher">
|
||
|
||
|
||
<ul class="links">
|
||
<li>
|
||
<a href="/research/clinical-trials/landmark-clinical-vision-and-eye-research/uveitis-research" class="language-link is-active" lang="en" data-drupal-link-system-path="node/3904" aria-current="page">English</a>
|
||
</li>
|
||
<li class="is-active">
|
||
<a href="/espanol/node/3904" class="language-link is-active" lang="es" data-drupal-link-system-path="node/3904" aria-current="page"> Español</a>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
</div>
|
||
<div class="search-global c-search--global" data-drupal-selector="search-global" id="block-globalsearchform" role="search">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<form action="/espanol/node/3904" method="post" id="search-global" accept-charset="UTF-8">
|
||
<div class="c-form__inner">
|
||
<div class="js-form-item form-item js-form-type-textfield form-item-global-terms js-form-item-global-terms">
|
||
<label for="edit-global-terms">Buscar en la página</label>
|
||
<input data-drupal-selector="edit-global-terms" type="text" id="edit-global-terms" name="global-terms" value="" size="30" maxlength="128" placeholder="Buscar en la página" class="form-text" />
|
||
|
||
</div>
|
||
<input data-drupal-selector="form-ld6e475f9rpepvl5tiratyljhkphzrgw577el-4tcuy" type="hidden" name="form_build_id" value="form-ld6E475F9RPePvL5TiratYlJHkpHzRgW577el-4tcUY" />
|
||
<input data-drupal-selector="edit-search-global" type="hidden" name="form_id" value="search_global" />
|
||
<div data-drupal-selector="edit-global-actions" class="form-actions js-form-wrapper form-wrapper" id="edit-global-actions"><input data-drupal-selector="edit-global-submit" type="submit" id="edit-global-submit" name="op" value="Buscar" class="button js-form-submit form-submit" />
|
||
</div>
|
||
|
||
</div>
|
||
</form>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="r-menu-primary">
|
||
<nav aria-label="Main navigation" id="block-mainnavigation" class="o-menu-main__outer">
|
||
|
||
<ul class="o-menu o-menu-main"> <li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/espanol/aprenda-sobre-la-salud-ocular" class="o-menu-main__link" data-drupal-link-system-path="node/39">Aprenda sobre la salud ocular</a>
|
||
<ul class="o-menu o-menu-main__submenu"> <li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/aprenda-sobre-la-salud-ocular/vision-saludable" class="o-menu-main__link" data-drupal-link-system-path="node/788">Visión saludable</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/aprenda-sobre-la-salud-ocular/enfermedades-y-afecciones-de-los-ojos" class="o-menu-main__link" data-drupal-link-system-path="learn-about-eye-health/eye-conditions-and-diseases">Enfermedades y afecciones de los ojos</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/aprenda-sobre-la-salud-ocular/datos-y-estadisticas-relacionadas-con-la-salud-ocular" class="o-menu-main__link" data-drupal-link-system-path="node/825">Datos y estadísticas relacionadas con la salud ocular</a>
|
||
</li>
|
||
<li class="o-menu-main__item"> <a href="/espanol/aprenda-sobre-la-salud-ocular/rehabilitacion-visual" class="o-menu-main__link" data-drupal-link-system-path="node/3865">Rehabilitación visual</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/aprenda-sobre-la-salud-ocular/campanas-de-difusion-y-recursos" class="o-menu-main__link" data-drupal-link-system-path="node/125">Campañas de difusión y recursos</a>
|
||
</li>
|
||
</ul>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--expanded o-menu-main__item--no-js"> <a href="/espanol/acerca-del-NEI" class="o-menu-main__link" data-drupal-link-system-path="node/275">Acerca del Instituto Nacional del Ojo</a>
|
||
<ul class="o-menu-main__submenu o-menu"> <li class="o-menu-main__item"> <a href="/espanol/acerca-del-NEI/planificacion-estrategica-en-el-nei" class="o-menu-main__link" data-drupal-link-system-path="node/2857">Planificación estratégica en el NEI</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/acerca-del-NEI/metas-y-logros" class="o-menu-main__link" data-drupal-link-system-path="node/281">Metas y logros</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/acerca-del-NEI/historia-del-nei" class="o-menu-main__link" data-drupal-link-system-path="node/282">Historia del NEI</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/acerca-del-NEI/lideres-del-instituto-nacional-del-ojo-nei" class="o-menu-main__link" data-drupal-link-system-path="node/415">Líderes del Instituto Nacional del Ojo (NEI)</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/acerca-del-NEI/el-presupuesto-y-el-congreso" class="o-menu-main__link" data-drupal-link-system-path="node/395">El presupuesto y el Congreso</a>
|
||
</li>
|
||
<li class="o-menu-main__item o-menu-main__item--collapsed"> <a href="/espanol/acerca-del-NEI/comites-asesores" class="o-menu-main__link" data-drupal-link-system-path="node/285">Comités asesores</a>
|
||
</li>
|
||
<li class="o-menu-main__item"> <a href="/espanol/aprenda-sobre-la-salud-ocular/campanas-de-difusion-y-recursos/programa-nacional-de-educacion-sobre-la-salud-del-ojo" title="National Eye Health Education Program" class="o-menu-main__link" data-drupal-link-system-path="node/265">Programa Nacional de Educación sobre la Salud del Ojo</a>
|
||
</li>
|
||
<li class="o-menu-main__item"> <a href="/espanol/acerca-del-NEI/done-al-instituto-nacional-del-ojo-nei" class="o-menu-main__link" data-drupal-link-system-path="node/286">Done al Instituto Nacional del Ojo (NEI)</a>
|
||
</li>
|
||
</ul>
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
</nav>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="o-overlay" aria-hidden="true"></div>
|
||
|
||
<div class="r-breadcrumb">
|
||
|
||
<div id="block-nei-breadcrumbs">
|
||
|
||
|
||
|
||
|
||
|
||
<nav aria-label="Breadcrumb">
|
||
<ol class="c-breadcrumb">
|
||
<li>
|
||
<a href="/espanol">Home</a>
|
||
</li>
|
||
<li>
|
||
Uveitis Research
|
||
</li>
|
||
</ol>
|
||
</nav>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="r-page-header">
|
||
<div class="o-page-header">
|
||
|
||
<div id="block-nei-page-title">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<h1>
|
||
<span>Uveitis Research </span>
|
||
</h1>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="block-jumpmenu-2">
|
||
|
||
|
||
|
||
|
||
|
||
<div class="c-jump-menu">
|
||
<div class="c-jump-menu__intro">En esta página:</div>
|
||
<a class="c-jump-menu__item" href="#section-id-19880">MUST Trial</a>
|
||
<a class="c-jump-menu__item" href="#section-id-19883">FAST Trial</a>
|
||
<a class="c-jump-menu__item" href="#section-id-19886">POINT </a>
|
||
<a class="c-jump-menu__item" href="#section-id-20393">MERIT Trial</a>
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="r-highlighted">
|
||
<div data-drupal-messages-fallback class="hidden"></div>
|
||
|
||
|
||
</div>
|
||
|
||
<div class="r-help">
|
||
|
||
</div>
|
||
<main id="main-content" class="r-main">
|
||
<div class="r-pre-content">
|
||
|
||
</div>
|
||
|
||
<div class="r-splitter">
|
||
<div class="r-content">
|
||
|
||
<div id="block-nei-content">
|
||
|
||
|
||
|
||
|
||
|
||
<article data-history-node-id="3904" lang="en">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>Uveitis — inflammation inside the eye — is a cause of vision loss in the United States. Clinical studies funded by NEI provide doctors, patients, and caregivers with the information they need to make informed health care decisions. And the results of these studies inform future research to identify effective treatments for uveitis.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="/learn-about-eye-health/eye-conditions-and-diseases/uveitis" class="c-link__link">Learn more about uveitis</a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-callout c-callout--wide c-callout--rounded" id="section-id-20281">
|
||
<div class="c-callout__content">
|
||
<h2 class="c-callout__heading">
|
||
|
||
|
||
|
||
|
||
Putting decades of eye health research into context
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>Scientific research is cumulative, with new breakthroughs advancing the field and changing the landscape. And given NEI’s long history of research, results that were groundbreaking decades ago may be less directly relevant today. The studies showcased here represent landmarks in eye health research that laid the groundwork the treatments, diagnostic tools, and prevention options that exist today.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="https://www.nei.nih.gov/about/news-and-events/news?topic=58&initiatives=All&research=All&source=All&date=All&language=All#views-exposed-form-news-page-page-1" class="c-link__link">Get the latest news about uveitis research</a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-section" id="section-id-19880">
|
||
<h2 class="c-section__heading">
|
||
|
||
|
||
|
||
|
||
MUST Trial
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>In 2005, researchers started the NEI-funded MUST (Multicenter Uveitis Steroid Treatment, <a href="https://www.clinicaltrials.gov/study/NCT00132691?cond=Multicenter%20Uveitis%20Steroid%20Treatment%20(MUST)%20Trial%20(MUST)&rank=1">NCT00132691</a>) Trial to compare 2 treatment options for people with uveitis. Researchers recruited 255 people with uveitis and randomly assigned them to receive 1 of 2 uveitis treatments:</p>
|
||
|
||
<ul>
|
||
<li class="Listbullets">Standard treatment with steroid and immunosuppressant pills — systemic treatments that affect the whole body</li>
|
||
<li class="Lastbullet">Treatment with a steroid eye implant (fluocinolone acetonide implant) — a local treatment that only affects the eye</li>
|
||
</ul>
|
||
|
||
<p>The MUST Trial set the standard of care for uveitis. It showed that for most people, standard treatment with steroid and immunosuppressant pills is safer and more effective than steroid implants.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="/about/news-and-events/news/systemic-therapy-outperforms-intraocular-implant-treating-uveitis" class="c-link__link">Learn more about the MUST Trial</a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-section" id="section-id-19883">
|
||
<h2 class="c-section__heading">
|
||
|
||
|
||
|
||
|
||
FAST Trial
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>In 2013, researchers started the NEI-funded FAST (First-line Antimetabolites for Steroid-sparing Treatment, <a href="https://www.clinicaltrials.gov/study/NCT01829295?cond=Methotrexate%20and%20Mycophenolate%20Mofetil%20for%20UVEITIS%20(FAST)&rank=1">NCT01829295</a>) Trial to compare 2 steroid-sparing immunosuppressant treatments for uveitis. These treatments change the body’s immune response to make it easier for steroids to work properly. The FAST Trial recruited 216 people with uveitis and randomly assigned them to receive 1 of 2 immunosuppressant treatments:</p>
|
||
|
||
<ul>
|
||
<li class="Listbullets">Methotrexate</li>
|
||
<li class="Lastbullet">Mycophenolate mofetil</li>
|
||
</ul>
|
||
|
||
<p>The FAST Trial was the first head-to-head comparison of these 2 treatments. It showed that methotrexate is as effective at treating uveitis — and in some cases, more effective — than mycophenolate.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="/about/news-and-events/news/two-commonly-used-uveitis-drugs-perform-similarly-nih-funded-clinical-trial" class="c-link__link">Learn more about the FAST Trial</a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-section" id="section-id-19886">
|
||
<h2 class="c-section__heading">
|
||
|
||
|
||
|
||
|
||
POINT Trial
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>In 2015, researchers started the NEI-funded POINT (PeriOcular vs. INTravitreal Corticosteroids for Uveitic Macular Edema Trial, <a href="https://www.clinicaltrials.gov/study/NCT02374060?term=NCT02374060&rank=1">NCT02374060</a>) to compare 3 treatments for uveitic <a href="https://www.nei.nih.gov/learn-about-eye-health/eye-conditions-and-diseases/macular-edema">macular edema</a>, a common complication of uveitis. The POINT Trial recruited 192 people with uveitic macular edema and randomly assigned them to receive 1 of 3 steroid treatments:</p>
|
||
|
||
<ul>
|
||
<li class="Listbullets">Periocular (near the eye) triamcinolone acetonide <a>injections</a></li>
|
||
<li class="Listbullets">Intravitreal (inside the eye) triamcinolone acetonide injections</li>
|
||
<li class="Lastbullet">Intravitreal injections to place implants that slowly release dexamethasone inside the eye over several months</li>
|
||
</ul>
|
||
|
||
<p>The POINT Trial was the first head-to-head comparison of these 3 steroid treatments. It showed that intravitreal delivery of either steroid was more effective than periocular delivery at controlling uveitic macular edema and preserving vision.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="/about/news-and-events/news/therapy-applied-directly-inside-eye-best-treating-uveitic-macular-edema" class="c-link__link">Learn more about the POINT Trial </a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-section" id="section-id-20393">
|
||
<h2 class="c-section__heading">
|
||
|
||
|
||
|
||
|
||
MERIT Trial
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<p>In 2017, researchers started the NEI-funded MERIT (Macular Edema Ranibizumab v. Intravitreal anti-inflammatory Therapy, <a href="https://clinicaltrials.gov/study/NCT02623426?term=MERIT&cond=Uveitis&rank=1">NCT02623426</a>) Trial to compare 3 treatments for uveitic <a href="/learn-about-eye-health/eye-conditions-and-diseases/macular-edema">macular edema</a>, a common complication of uveitis. The most common treatment for this condition is corticosteroids to reduce inflammation and swelling of the retina. However, intravitreal (inside the eye) corticosteroid injections can increase the pressure in the eye, raising the risk of glaucoma. The MERIT trial recruited 194 people with well-controlled uveitis — but persistent or recurring macular edema — and assigned them to receive 1 of 3 intravitreal injections of:</p>
|
||
|
||
<ul>
|
||
<li class="Listbullets"><span><span>Dexamethasone — an additional corticosteroid</span></span></li>
|
||
<li class="Listbullets"><span><span>Ranibizumab — anti-vascular endothelial growth factor (anti-VEGF)</span></span></li>
|
||
<li class="Lastbullet"><span><span>Methotrexate — anti-inflammatory</span></span></li>
|
||
</ul>
|
||
|
||
<p>The MERIT Trial was the first study to compare different treatments for persistent or recurring macular edema in patients with uveitis. It showed that despite the risk, intravitreal corticosteroid injections are the most effective treatment for this condition — lowering retinal swelling and improving vision better than ranibizumab or methotrexate injections.</p>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-link">
|
||
|
||
<a href="/about/news-and-events/news/intraocular-corticosteroids-best-treating-complications-chronic-inflammatory-eye-condition" class="c-link__link">Learn more about the MERIT Trial</a>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-callout c-callout--wide c-callout--rounded" id="section-id-20187">
|
||
<figure class="c-callout__image">
|
||
<img src="https://www.nei.nih.gov/sites/default/files/styles/400px_square_crop/public/2019-03/icon_red_investigate_BG.png?itok=nLPxbSx4" alt="" />
|
||
</figure>
|
||
<div class="c-callout__content">
|
||
<h2 class="c-callout__heading">
|
||
|
||
|
||
|
||
|
||
Learn more
|
||
|
||
|
||
</h2>
|
||
|
||
|
||
|
||
|
||
<div class="c-text">
|
||
|
||
|
||
|
||
|
||
<ul>
|
||
<li><a href="/about/news-and-events/news?topic=58&initiatives=All&research=All&source=All&created=All&language=All">Get the latest news on NEI-supported uveitis research</a></li>
|
||
<li><a href="/research/clinical-trials/learn-about-clinical-trials">Learn about clinical trials</a></li>
|
||
<li><a href="/grants-and-training/funding-opportunities/current-funding-opportunities">Explore current NEI funding opportunities</a></li>
|
||
<li><a href="/grants-and-training/funding-opportunities/programs-and-research-priorities">Get an overview of NEI’s programs and research priorities</a></li>
|
||
</ul>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</article>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<p class="views-element-container c-last-updated" id="block-views-block-nei-last-updated-block-1"><strong>Actualización más reciente:</strong> 14 de agosto de 2023</p>
|
||
|
||
|
||
</div>
|
||
<aside class="r-sidebar" role="complementary">
|
||
|
||
<div class="views-element-container" id="block-views-block-nei-sidebar-block-1">
|
||
|
||
|
||
|
||
|
||
|
||
<div>
|
||
<div class="js-view-dom-id-86654d900a492a289f78ba55cac9bdd8935456b87d1bc3721f0ebf26b5adde55 nei-sidebar">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="views-row">
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</aside>
|
||
</div>
|
||
</main>
|
||
|
||
<div class="r-footer">
|
||
<footer class="o-footer" role="contentinfo">
|
||
|
||
<div id="block-footer-2">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="o-footer__row">
|
||
<div class="o-footer__group o-footer__group--logo"><a class="o-logo__link" href="/" rel="home" title="Home"><span class="o-logo__text">National Eye Institute</span></a>
|
||
<ul class="o-menu-social">
|
||
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--facebook outlink-ignore" href="https://www.facebook.com/NationalEyeInstitute">Facebook</a></li>
|
||
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--twitter outlink-ignore" href="https://twitter.com/NatEyeInstitute">Twitter</a></li>
|
||
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--linkedin outlink-ignore" href="https://www.linkedin.com/company/national-eye-institute-nei">LinkedIn</a></li>
|
||
<li class="o-menu-social__item"><a class="o-menu-social__link o-menu-social__link--youtube outlink-ignore" href="https://www.youtube.com/user/neinih">YouTube</a></li>
|
||
</ul>
|
||
|
||
<p> </p>
|
||
</div>
|
||
|
||
<div class="o-footer__group o-footer__group--contact">
|
||
<h2 class="o-footer__title">Contactenos NEI</h2>
|
||
|
||
<ul class="o-menu-footer">
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/contactenos">Contáctenos</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/about-nih/visitor-information">Visite a los NIH (en inglés)</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://list.nih.gov/cgi-bin/wa.exe?SUBED1=insidenei&A=1">Reciba actualizaciones del NEI a través del correo electrónico (en inglés)</a></li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="o-footer__group o-footer__group--policies">
|
||
<h2 class="o-footer__title">Politicas</h2>
|
||
|
||
<ul class="o-menu-footer">
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/informacion-sobre-accesibilidad">Accesibilidad</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/nondiscrimination-notice-language-assistance-services#spanish">Información en otros idiomas</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/ley-de-libertad-de-informacion-foia">Política de privacidad</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/ley-de-libertad-de-informacion-foia">Ley de Libertad de Información (FOIA)</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/descargo-de-responsabilidades">Descargo de responsabilidades</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="/espanol/politicas-de-la-pagina-web">Políticas de la página web</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html ">Declaración sobre vulnerabilidad (en inglés)</a></li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="o-footer__group o-footer__group--employees">
|
||
<h2 class="o-footer__title">Para los empleados de NEI</h2>
|
||
|
||
<ul class="o-menu-footer">
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://intranet.nei.nih.gov">Intranet</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://intranet.nei.nih.gov/hr/Pages/emergency.aspx">Información de emergencia</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://ned.nih.gov/search/search.aspx">Directorio de los funcionarios del NEI</a></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="o-footer__row">
|
||
<div class="o-footer__full o-footer__full--parent">
|
||
<ul class="o-menu-footer o-menu-footer--swing">
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://www.nih.gov/">NIH.gov</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://hhs.gov/">HHS.gov</a></li>
|
||
<li class="o-menu-footer__item"><a class="o-menu-footer__link" href="https://usa.gov/">USA.gov</a></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</footer>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="c-lb-wrapper" id="lb-wrapper" aria-hidden="true">
|
||
<div class="c-lb-overlay" tabindex="-1"></div>
|
||
<div role="dialog" class="c-lb" id="lb">
|
||
<div class="c-lb-header">
|
||
<button class="c-lb-close-btn"><span class="c-lb-close-btn-text">Close</span><span class="c-lb-close-btn-text times" aria-hidden="true">×</span></button>
|
||
</div>
|
||
<figure class="c-lb-figure">
|
||
<figcaption class="c-lb-caption"></figcaption>
|
||
</figure>
|
||
</div>
|
||
</div>
|
||
|
||
<script src="/sites/default/files/js/js_P5UBl7ML5jj6dp4P_zp1vfnURYj58JsfQMLHLuwiELA.js?scope=footer&delta=0&language=es&theme=nei&include=eJxdjEEOgCAMBD-E9kmkYrOpqdQAMerr5eBBvUx29jCp8HUKQOkZAe4wiY1B6Pj7yAsf33MNmZvuEq0nojnPmkFvCVmUYD6xDTUV3Vq9ATUbLxk"></script>
|
||
<script src="/themes/custom/nei/js/scripts.js?sraguf"></script>
|
||
|
||
</body>
|
||
</html>
|