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Updated: February, 2025
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<span class="headername">Database of Clusters of Orthologous Genes (COGs)</span>
<ul data-jig="ncbimenu" id="ui-ncbimenu-1" role="menubar">
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<a href="/research/cog/" title="Home" class="uppercase" role="menuitem"
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COG Database
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COG Categories
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<a href="/research/cog/cogcategory/J/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
J - Translation, ribosomal structure and biogenesis</a>
<a href="/research/cog/cogcategory/A/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
A - RNA processing and modification</a>
<a href="/research/cog/cogcategory/K/" title="COG Categories"
class="uppercase"
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style="font-weight: normal;"
id="ui-ncbimenu-1_2">
K - Transcription</a>
<a href="/research/cog/cogcategory/L/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
L - Replication, recombination and repair</a>
<a href="/research/cog/cogcategory/B/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
B - Chromatin structure and dynamics</a>
<a href="/research/cog/cogcategory/D/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
D - Cell cycle control, cell division, chromosome partitioning</a>
<a href="/research/cog/cogcategory/Y/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
Y - Nuclear structure</a>
<a href="/research/cog/cogcategory/V/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
V - Defense mechanisms</a>
<a href="/research/cog/cogcategory/T/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
T - Signal transduction mechanisms</a>
<a href="/research/cog/cogcategory/M/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
M - Cell wall/membrane/envelope biogenesis</a>
<a href="/research/cog/cogcategory/N/" title="COG Categories"
class="uppercase"
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N - Cell motility</a>
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Z - Cytoskeleton</a>
<a href="/research/cog/cogcategory/W/" title="COG Categories"
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W - Extracellular structures</a>
<a href="/research/cog/cogcategory/U/" title="COG Categories"
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U - Intracellular trafficking, secretion, and vesicular transport</a>
<a href="/research/cog/cogcategory/O/" title="COG Categories"
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O - Posttranslational modification, protein turnover, chaperones</a>
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class="uppercase"
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X - nan</a>
<a href="/research/cog/cogcategory/C/" title="COG Categories"
class="uppercase"
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C - Energy production and conversion</a>
<a href="/research/cog/cogcategory/G/" title="COG Categories"
class="uppercase"
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id="ui-ncbimenu-1_2">
G - Carbohydrate transport and metabolism</a>
<a href="/research/cog/cogcategory/E/" title="COG Categories"
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E - Amino acid transport and metabolism</a>
<a href="/research/cog/cogcategory/F/" title="COG Categories"
class="uppercase"
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style="font-weight: normal;"
id="ui-ncbimenu-1_2">
F - Nucleotide transport and metabolism</a>
<a href="/research/cog/cogcategory/H/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
H - Coenzyme transport and metabolism</a>
<a href="/research/cog/cogcategory/I/" title="COG Categories"
class="uppercase"
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style="font-weight: normal;"
id="ui-ncbimenu-1_2">
I - Lipid transport and metabolism</a>
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class="uppercase"
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P - Inorganic ion transport and metabolism</a>
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Q - Secondary metabolites biosynthesis, transport and catabolism</a>
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S - Function unknown</a>
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<main id="main_content" accesskey="3">
<section class="usa-section cog_top_section">
<div class="usa-grid">
<h1>R<span style='font-weight: 100'> - General function prediction only</span></h1>
<div style="float: right; clear: both;margin-top: -53px;">
<a class="usa-button" href="#" onclick="download_table_as_tsv('cog_result_table');">Download</a>
</div>
<h2>Stats</h2>
<div style="width: 60%">
<div class="ui-ncbigrid-outer-div organism_cog_table">
<div class="ui-ncbigrid-inner-div">
<table data-jig="ncbigrid">
<thead>
<tr>
<th>COG<br>definitions</th>
<th>Organims</th>
<th>Proteins</th>
<th>Median Protein<br>Length</th>
<th>Genes</th>
</tr>
</thead>
<tbody>
<tr>
<td>560</td>
<td>2,289</td>
<td>510,474</td>
<td>307.0</td>
<td>297</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="ui-ncbigrid-outer-div" style="font-size: 80%;">
<div class="ui-ncbigrid-inner-div">
<table id="cog_result_table" data-jig="ncbigrid">
<thead>
<tr>
<th>Organism</th>
<th>Protein</th>
<th>COG</th>
<th>Cat</th>
<th>Annotation</th>
</tr>
</thead>
<tbody>
<tr>
<td>1669</td>
<td>4258</td>
<td><a href="/research/cog/cog/COG0110/">COG0110</a></td>
<td>
R
</td>
<td>O-acetyltransferase, isoleucine patch superfamily, LacA/YvoF/WbbJ family</td>
</tr>
<tr>
<td>674</td>
<td>821</td>
<td><a href="/research/cog/cog/COG0121/">COG0121</a></td>
<td>
R
</td>
<td>Predicted glutamine amidotransferase YafJ</td>
</tr>
<tr>
<td>1884</td>
<td>9239</td>
<td><a href="/research/cog/cog/COG0300/">COG0300</a></td>
<td>
R
</td>
<td>Short-chain dehydrogenase</td>
</tr>
<tr>
<td>1131</td>
<td>1547</td>
<td><a href="/research/cog/cog/COG0384/">COG0384</a></td>
<td>
R
</td>
<td>Predicted epimerase YddE/YHI9, PhzF superfamily</td>
</tr>
<tr>
<td>1073</td>
<td>1560</td>
<td><a href="/research/cog/cog/COG0385/">COG0385</a></td>
<td>
R
</td>
<td>Predicted Na+-dependent transporter YfeH</td>
</tr>
<tr>
<td>1204</td>
<td>1714</td>
<td><a href="/research/cog/cog/COG0400/">COG0400</a></td>
<td>
R
</td>
<td>Palmitoyl-CoA esterase</td>
</tr>
<tr>
<td>1624</td>
<td>4467</td>
<td><a href="/research/cog/cog/COG0402/">COG0402</a></td>
<td>
F
R
</td>
<td>Cytosine/adenosine deaminase or related metal-dependent hydrolase</td>
</tr>
<tr>
<td>635</td>
<td>679</td>
<td><a href="/research/cog/cog/COG0429/">COG0429</a></td>
<td>
R
</td>
<td>Predicted hydrolase of the alpha/beta-hydrolase fold</td>
</tr>
<tr>
<td>115</td>
<td>124</td>
<td><a href="/research/cog/cog/COG0454/">COG0454</a></td>
<td>
K
R
</td>
<td>N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2)</td>
</tr>
<tr>
<td>1537</td>
<td>8665</td>
<td><a href="/research/cog/cog/COG0457/">COG0457</a></td>
<td>
R
</td>
<td>Tetratricopeptide (TPR) repeat</td>
</tr>
<tr>
<td>846</td>
<td>2343</td>
<td><a href="/research/cog/cog/COG0477/">COG0477</a></td>
<td>
G
E
P
R
</td>
<td>MFS family permease, includes anhydromuropeptide permease AmpG</td>
</tr>
<tr>
<td>2130</td>
<td>11220</td>
<td><a href="/research/cog/cog/COG0491/">COG0491</a></td>
<td>
R
</td>
<td>Glyoxylase or a related metal-dependent hydrolase, beta-lactamase superfamily II</td>
</tr>
<tr>
<td>1785</td>
<td>4090</td>
<td><a href="/research/cog/cog/COG0493/">COG0493</a></td>
<td>
E
R
</td>
<td>NADPH-dependent glutamate synthase beta chain or related oxidoreductase</td>
</tr>
<tr>
<td>166</td>
<td>179</td>
<td><a href="/research/cog/cog/COG0500/">COG0500</a></td>
<td>
Q
R
</td>
<td>SAM-dependent methyltransferase SmtA (CmoB moved to COG2228)</td>
</tr>
<tr>
<td>1207</td>
<td>2680</td>
<td><a href="/research/cog/cog/COG0523/">COG0523</a></td>
<td>
R
</td>
<td>Zinc metallochaperone YeiR/ZagA and related GTPases, G3E family</td>
</tr>
<tr>
<td>2239</td>
<td>4083</td>
<td><a href="/research/cog/cog/COG0537/">COG0537</a></td>
<td>
F
R
</td>
<td>Purine nucleoside phosphoramidase/Ap4A hydrolase, histidine triade (HIT) family</td>
</tr>
<tr>
<td>1605</td>
<td>4596</td>
<td><a href="/research/cog/cog/COG0561/">COG0561</a></td>
<td>
H
R
</td>
<td>Hydroxymethylpyrimidine pyrophosphatase and other HAD family phosphatases</td>
</tr>
<tr>
<td>2096</td>
<td>22530</td>
<td><a href="/research/cog/cog/COG0596/">COG0596</a></td>
<td>
H
R
</td>
<td>2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH/undecaprenyl monophosphate-sugar esterase UshA/YqjL</td>
</tr>
<tr>
<td>1360</td>
<td>2555</td>
<td><a href="/research/cog/cog/COG0599/">COG0599</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YurZ, alkylhydroperoxidase/carboxymuconolactone decarboxylase family</td>
</tr>
<tr>
<td>1655</td>
<td>8394</td>
<td><a href="/research/cog/cog/COG0604/">COG0604</a></td>
<td>
C
R
</td>
<td>NADPH:quinone reductase or related Zn-dependent oxidoreductase</td>
</tr>
<tr>
<td>1842</td>
<td>4923</td>
<td><a href="/research/cog/cog/COG0612/">COG0612</a></td>
<td>
R
</td>
<td>Predicted Zn-dependent peptidase, M16 family</td>
</tr>
<tr>
<td>1395</td>
<td>2500</td>
<td><a href="/research/cog/cog/COG0622/">COG0622</a></td>
<td>
R
</td>
<td>Mn2+-dependent phosphodiesterase, calcineurin family</td>
</tr>
<tr>
<td>2121</td>
<td>5839</td>
<td><a href="/research/cog/cog/COG0628/">COG0628</a></td>
<td>
R
</td>
<td>Predicted PurR-regulated permease PerM</td>
</tr>
<tr>
<td>728</td>
<td>916</td>
<td><a href="/research/cog/cog/COG0645/">COG0645</a></td>
<td>
R
</td>
<td>Predicted kinase, contains AAA domain</td>
</tr>
<tr>
<td>1621</td>
<td>2419</td>
<td><a href="/research/cog/cog/COG0663/">COG0663</a></td>
<td>
R
</td>
<td>Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily</td>
</tr>
<tr>
<td>1757</td>
<td>8211</td>
<td><a href="/research/cog/cog/COG0667/">COG0667</a></td>
<td>
H
R
</td>
<td>Pyridoxal reductase PdxI or related oxidoreductase, aldo/keto reductase family</td>
</tr>
<tr>
<td>1864</td>
<td>13722</td>
<td><a href="/research/cog/cog/COG0673/">COG0673</a></td>
<td>
R
</td>
<td>Predicted dehydrogenase</td>
</tr>
<tr>
<td>1466</td>
<td>2716</td>
<td><a href="/research/cog/cog/COG0679/">COG0679</a></td>
<td>
R
</td>
<td>Predicted permease, AEC (auxin efflux carrier) family</td>
</tr>
<tr>
<td>2068</td>
<td>13867</td>
<td><a href="/research/cog/cog/COG0697/">COG0697</a></td>
<td>
E
R
</td>
<td>Amino acid export permease, drug/metabolite transporter (DMT) superfamily</td>
</tr>
<tr>
<td>1453</td>
<td>4449</td>
<td><a href="/research/cog/cog/COG0702/">COG0702</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains</td>
</tr>
<tr>
<td>1941</td>
<td>7177</td>
<td><a href="/research/cog/cog/COG0714/">COG0714</a></td>
<td>
R
</td>
<td>MoxR-like ATPase, includes components of a predicted archaeal secretion system</td>
</tr>
<tr>
<td>862</td>
<td>1301</td>
<td><a href="/research/cog/cog/COG0727/">COG0727</a></td>
<td>
R
</td>
<td>Uncharacterized protein YkgJ, contains CxxCxxCC motif</td>
</tr>
<tr>
<td>881</td>
<td>1542</td>
<td><a href="/research/cog/cog/COG0733/">COG0733</a></td>
<td>
R
</td>
<td>Na+-dependent transporter, SNF family</td>
</tr>
<tr>
<td>1008</td>
<td>3397</td>
<td><a href="/research/cog/cog/COG0790/">COG0790</a></td>
<td>
R
</td>
<td>Sel1-like repeat, TPR-related</td>
</tr>
<tr>
<td>664</td>
<td>726</td>
<td><a href="/research/cog/cog/COG0857/">COG0857</a></td>
<td>
R
</td>
<td>BioD-like N-terminal domain of phosphotransacetylase</td>
</tr>
<tr>
<td>157</td>
<td>158</td>
<td><a href="/research/cog/cog/COG1031/">COG1031</a></td>
<td>
R
</td>
<td>Radical SAM superfamily enzyme with C-terminal helix-hairpin-helix motif</td>
</tr>
<tr>
<td>1388</td>
<td>4492</td>
<td><a href="/research/cog/cog/COG1032/">COG1032</a></td>
<td>
R
</td>
<td>Radical SAM superfamily enzyme YgiQ, UPF0313 family</td>
</tr>
<tr>
<td>891</td>
<td>1732</td>
<td><a href="/research/cog/cog/COG1033/">COG1033</a></td>
<td>
R
</td>
<td>Predicted exporter protein, RND superfamily</td>
</tr>
<tr>
<td>1983</td>
<td>2123</td>
<td><a href="/research/cog/cog/COG1040/">COG1040</a></td>
<td>
R
</td>
<td>DNA utilization protein ComFC/GntX, contains phosphoribosyltransferase domain</td>
</tr>
<tr>
<td>1573</td>
<td>3063</td>
<td><a href="/research/cog/cog/COG1052/">COG1052</a></td>
<td>
C
H
R
</td>
<td>Lactate dehydrogenase or related 2-hydroxyacid dehydrogenase</td>
</tr>
<tr>
<td>1667</td>
<td>5740</td>
<td><a href="/research/cog/cog/COG1063/">COG1063</a></td>
<td>
E
R
</td>
<td>Threonine dehydrogenase or related Zn-dependent dehydrogenase</td>
</tr>
<tr>
<td>734</td>
<td>891</td>
<td><a href="/research/cog/cog/COG1078/">COG1078</a></td>
<td>
R
</td>
<td>HD superfamily phosphohydrolase</td>
</tr>
<tr>
<td>164</td>
<td>165</td>
<td><a href="/research/cog/cog/COG1084/">COG1084</a></td>
<td>
R
</td>
<td>GTP-binding protein, GTP1/Obg family</td>
</tr>
<tr>
<td>1030</td>
<td>1244</td>
<td><a href="/research/cog/cog/COG1090/">COG1090</a></td>
<td>
R
</td>
<td>NAD dependent epimerase/dehydratase family enzyme</td>
</tr>
<tr>
<td>333</td>
<td>463</td>
<td><a href="/research/cog/cog/COG1098/">COG1098</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains ribosomal protein S1 (RPS1) domain</td>
</tr>
<tr>
<td>227</td>
<td>242</td>
<td><a href="/research/cog/cog/COG1099/">COG1099</a></td>
<td>
R
</td>
<td>Predicted metal-dependent hydrolase, TIM-barrel fold</td>
</tr>
<tr>
<td>281</td>
<td>805</td>
<td><a href="/research/cog/cog/COG1100/">COG1100</a></td>
<td>
R
</td>
<td>GTPase SAR1 family domain</td>
</tr>
<tr>
<td>459</td>
<td>547</td>
<td><a href="/research/cog/cog/COG1101/">COG1101</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, ATPase component</td>
</tr>
<tr>
<td>386</td>
<td>542</td>
<td><a href="/research/cog/cog/COG1106/">COG1106</a></td>
<td>
R
</td>
<td>ATPase/GTPase, AAA15 family</td>
</tr>
<tr>
<td>1206</td>
<td>3024</td>
<td><a href="/research/cog/cog/COG1122/">COG1122</a></td>
<td>
P
R
</td>
<td>Energy-coupling factor transporter ATP-binding protein EcfA2</td>
</tr>
<tr>
<td>655</td>
<td>1583</td>
<td><a href="/research/cog/cog/COG1149/">COG1149</a></td>
<td>
R
</td>
<td>MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain</td>
</tr>
<tr>
<td>853</td>
<td>1083</td>
<td><a href="/research/cog/cog/COG1168/">COG1168</a></td>
<td>
E
R
</td>
<td>Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities</td>
</tr>
<tr>
<td>2035</td>
<td>3482</td>
<td><a href="/research/cog/cog/COG1181/">COG1181</a></td>
<td>
M
R
</td>
<td>D-alanine-D-alanine ligase or related ATP-grasp enzyme</td>
</tr>
<tr>
<td>414</td>
<td>542</td>
<td><a href="/research/cog/cog/COG1237/">COG1237</a></td>
<td>
R
</td>
<td>Metal-dependent hydrolase, beta-lactamase superfamily II</td>
</tr>
<tr>
<td>547</td>
<td>584</td>
<td><a href="/research/cog/cog/COG1242/">COG1242</a></td>
<td>
R
</td>
<td>Radical SAM superfamily enzyme</td>
</tr>
<tr>
<td>88</td>
<td>88</td>
<td><a href="/research/cog/cog/COG1255/">COG1255</a></td>
<td>
R
</td>
<td>Predicted small methyltransferase MTH1000, UPF0146 family</td>
</tr>
<tr>
<td>821</td>
<td>878</td>
<td><a href="/research/cog/cog/COG1259/">COG1259</a></td>
<td>
A
R
</td>
<td>Bifunctional DNase/RNase</td>
</tr>
<tr>
<td>389</td>
<td>570</td>
<td><a href="/research/cog/cog/COG1288/">COG1288</a></td>
<td>
R
</td>
<td>Predicted membrane transporter YfcC, affects glyoxylate shunt</td>
</tr>
<tr>
<td>688</td>
<td>1378</td>
<td><a href="/research/cog/cog/COG1289/">COG1289</a></td>
<td>
R
</td>
<td>Aromatic carboxylic acid efflux pump AaeB or related transporter, AaeB/MdtO/YccS family</td>
</tr>
<tr>
<td>418</td>
<td>518</td>
<td><a href="/research/cog/cog/COG1297/">COG1297</a></td>
<td>
R
</td>
<td>Predicted oligopeptide transporter, OPT family</td>
</tr>
<tr>
<td>1328</td>
<td>2098</td>
<td><a href="/research/cog/cog/COG1304/">COG1304</a></td>
<td>
C
I
R
</td>
<td>FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase</td>
</tr>
<tr>
<td>189</td>
<td>203</td>
<td><a href="/research/cog/cog/COG1306/">COG1306</a></td>
<td>
R
</td>
<td>Predicted glycosyl hydrolase, alpha amylase family</td>
</tr>
<tr>
<td>319</td>
<td>348</td>
<td><a href="/research/cog/cog/COG1313/">COG1313</a></td>
<td>
R
</td>
<td>Radical SAM superfamily enzyme PflX</td>
</tr>
<tr>
<td>109</td>
<td>111</td>
<td><a href="/research/cog/cog/COG1326/">COG1326</a></td>
<td>
R
</td>
<td>Uncharacterized archaeal Zn-finger protein</td>
</tr>
<tr>
<td>1052</td>
<td>1514</td>
<td><a href="/research/cog/cog/COG1331/">COG1331</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains</td>
</tr>
<tr>
<td>521</td>
<td>544</td>
<td><a href="/research/cog/cog/COG1334/">COG1334</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, FlaG/YvyC family</td>
</tr>
<tr>
<td>1776</td>
<td>4907</td>
<td><a href="/research/cog/cog/COG1335/">COG1335</a></td>
<td>
H
R
</td>
<td>Nicotinamidase-related amidase</td>
</tr>
<tr>
<td>337</td>
<td>432</td>
<td><a href="/research/cog/cog/COG1342/">COG1342</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein, UPF0251 family</td>
</tr>
<tr>
<td>500</td>
<td>562</td>
<td><a href="/research/cog/cog/COG1355/">COG1355</a></td>
<td>
R
</td>
<td>Predicted class III extradiol dioxygenase, MEMO1 family</td>
</tr>
<tr>
<td>217</td>
<td>386</td>
<td><a href="/research/cog/cog/COG1361/">COG1361</a></td>
<td>
R
</td>
<td>S-layer protein MJ0795, predicted component of type IV pili-like system</td>
</tr>
<tr>
<td>17</td>
<td>19</td>
<td><a href="/research/cog/cog/COG1365/">COG1365</a></td>
<td>
R
</td>
<td>Predicted ATPase, PP-loop superfamily</td>
</tr>
<tr>
<td>652</td>
<td>1900</td>
<td><a href="/research/cog/cog/COG1373/">COG1373</a></td>
<td>
R
</td>
<td>Predicted ATPase, AAA+ superfamily</td>
</tr>
<tr>
<td>304</td>
<td>337</td>
<td><a href="/research/cog/cog/COG1379/">COG1379</a></td>
<td>
R
</td>
<td>PHP family phosphoesterase with a Zn ribbon</td>
</tr>
<tr>
<td>663</td>
<td>775</td>
<td><a href="/research/cog/cog/COG1380/">COG1380</a></td>
<td>
R
</td>
<td>Putative effector of murein hydrolase LrgA, UPF0299 family</td>
</tr>
<tr>
<td>1098</td>
<td>1897</td>
<td><a href="/research/cog/cog/COG1387/">COG1387</a></td>
<td>
E
R
</td>
<td>Histidinol phosphatase or related hydrolase of the PHP family</td>
</tr>
<tr>
<td>595</td>
<td>692</td>
<td><a href="/research/cog/cog/COG1407/">COG1407</a></td>
<td>
R
</td>
<td>Metallophosphoesterase superfamily enzyme</td>
</tr>
<tr>
<td>1193</td>
<td>1830</td>
<td><a href="/research/cog/cog/COG1408/">COG1408</a></td>
<td>
M
R
</td>
<td>Phosphohydrolase of MPP superfamily, includes undecaprenyl diphosphate-linked teichoic acid hydrolase UpsH/YpbG</td>
</tr>
<tr>
<td>133</td>
<td>134</td>
<td><a href="/research/cog/cog/COG1411/">COG1411</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein related to proFAR isomerase (HisA)</td>
</tr>
<tr>
<td>817</td>
<td>3011</td>
<td><a href="/research/cog/cog/COG1413/">COG1413</a></td>
<td>
R
</td>
<td>HEAT repeat</td>
</tr>
<tr>
<td>1291</td>
<td>2209</td>
<td><a href="/research/cog/cog/COG1418/">COG1418</a></td>
<td>
J
R
</td>
<td>HD superfamily phosphodiesterase, includes HD domain of RNase Y</td>
</tr>
<tr>
<td>1216</td>
<td>1755</td>
<td><a href="/research/cog/cog/COG1432/">COG1432</a></td>
<td>
R
</td>
<td>NYN domain, predicted PIN-related RNAse, tRNA/rRNA maturation</td>
</tr>
<tr>
<td>405</td>
<td>454</td>
<td><a href="/research/cog/cog/COG1437/">COG1437</a></td>
<td>
T
R
</td>
<td>Adenylate cyclase class IV, CYTH domain (includes archaeal enzymes of unknown function)</td>
</tr>
<tr>
<td>1393</td>
<td>1775</td>
<td><a href="/research/cog/cog/COG1451/">COG1451</a></td>
<td>
R
</td>
<td>UTP pyrophosphatase, metal-dependent hydrolase family</td>
</tr>
<tr>
<td>433</td>
<td>895</td>
<td><a href="/research/cog/cog/COG1453/">COG1453</a></td>
<td>
R
</td>
<td>Predicted oxidoreductase of the aldo/keto reductase family</td>
</tr>
<tr>
<td>1574</td>
<td>4269</td>
<td><a href="/research/cog/cog/COG1473/">COG1473</a></td>
<td>
R
</td>
<td>Metal-dependent amidase/aminoacylase/carboxypeptidase</td>
</tr>
<tr>
<td>203</td>
<td>246</td>
<td><a href="/research/cog/cog/COG1483/">COG1483</a></td>
<td>
R
</td>
<td>Predicted ATPase, AAA+ superfamily</td>
</tr>
<tr>
<td>207</td>
<td>208</td>
<td><a href="/research/cog/cog/COG1491/">COG1491</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding OB-fold protein</td>
</tr>
<tr>
<td>66</td>
<td>79</td>
<td><a href="/research/cog/cog/COG1532/">COG1532</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein</td>
</tr>
<tr>
<td>506</td>
<td>1367</td>
<td><a href="/research/cog/cog/COG1545/">COG1545</a></td>
<td>
R
</td>
<td>Uncharacterized OB-fold protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>319</td>
<td>354</td>
<td><a href="/research/cog/cog/COG1563/">COG1563</a></td>
<td>
R
</td>
<td>Uncharacterized MnhB-related membrane protein, DUF4040 domain</td>
</tr>
<tr>
<td>799</td>
<td>813</td>
<td><a href="/research/cog/cog/COG1565/">COG1565</a></td>
<td>
R
</td>
<td>SAM-dependent methyltransferase, MidA family</td>
</tr>
<tr>
<td>387</td>
<td>630</td>
<td><a href="/research/cog/cog/COG1569/">COG1569</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains PIN domain</td>
</tr>
<tr>
<td>426</td>
<td>794</td>
<td><a href="/research/cog/cog/COG1572/">COG1572</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains cell adhesion related (CARDB) domains</td>
</tr>
<tr>
<td>1104</td>
<td>2085</td>
<td><a href="/research/cog/cog/COG1574/">COG1574</a></td>
<td>
R
</td>
<td>Predicted amidohydrolase YtcJ</td>
</tr>
<tr>
<td>836</td>
<td>890</td>
<td><a href="/research/cog/cog/COG1579/">COG1579</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain</td>
</tr>
<tr>
<td>1444</td>
<td>2616</td>
<td><a href="/research/cog/cog/COG1597/">COG1597</a></td>
<td>
I
R
</td>
<td>Phosphatidylglycerol kinase, diacylglycerol kinase family</td>
</tr>
<tr>
<td>617</td>
<td>656</td>
<td><a href="/research/cog/cog/COG1606/">COG1606</a></td>
<td>
R
</td>
<td>ATP-utilizing enzyme, PP-loop superfamily</td>
</tr>
<tr>
<td>1473</td>
<td>1482</td>
<td><a href="/research/cog/cog/COG1610/">COG1610</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YqeY, may have tRNA amino acid amidase activity</td>
</tr>
<tr>
<td>15</td>
<td>15</td>
<td><a href="/research/cog/cog/COG1627/">COG1627</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein MJ0835, predicted component of type IV pili-like system, DUF1515 family</td>
</tr>
<tr>
<td>195</td>
<td>197</td>
<td><a href="/research/cog/cog/COG1628/">COG1628</a></td>
<td>
R
</td>
<td>Endonuclease V homolog, UPF0215 family</td>
</tr>
<tr>
<td>169</td>
<td>171</td>
<td><a href="/research/cog/cog/COG1645/">COG1645</a></td>
<td>
R
</td>
<td>Uncharacterized Zn-finger containing protein, UPF0148 family</td>
</tr>
<tr>
<td>336</td>
<td>341</td>
<td><a href="/research/cog/cog/COG1656/">COG1656</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains PIN-related Mut7-C RNAse domain</td>
</tr>
<tr>
<td>433</td>
<td>495</td>
<td><a href="/research/cog/cog/COG1661/">COG1661</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein with PD1-like DNA-binding motif, PPC/DUF296 domain</td>
</tr>
<tr>
<td>88</td>
<td>107</td>
<td><a href="/research/cog/cog/COG1665/">COG1665</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase AF1967</td>
</tr>
<tr>
<td>787</td>
<td>2101</td>
<td><a href="/research/cog/cog/COG1669/">COG1669</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase MJ0435</td>
</tr>
<tr>
<td>340</td>
<td>683</td>
<td><a href="/research/cog/cog/COG1672/">COG1672</a></td>
<td>
R
</td>
<td>Predicted ATPase, archaeal AAA+ ATPase superfamily</td>
</tr>
<tr>
<td>54</td>
<td>72</td>
<td><a href="/research/cog/cog/COG1673/">COG1673</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains PUA-like EVE domain</td>
</tr>
<tr>
<td>43</td>
<td>46</td>
<td><a href="/research/cog/cog/COG1689/">COG1689</a></td>
<td>
R
</td>
<td>Class II terpene cyclase family protein AF1543</td>
</tr>
<tr>
<td>42</td>
<td>46</td>
<td><a href="/research/cog/cog/COG1707/">COG1707</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains ACT and PBP-like DUF5612 domains, MJ1458 family</td>
</tr>
<tr>
<td>342</td>
<td>587</td>
<td><a href="/research/cog/cog/COG1708/">COG1708</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase, MJ0604 family</td>
</tr>
<tr>
<td>22</td>
<td>27</td>
<td><a href="/research/cog/cog/COG1710/">COG1710</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein MJ1475, contains C-terminal HTH domain</td>
</tr>
<tr>
<td>503</td>
<td>530</td>
<td><a href="/research/cog/cog/COG1713/">COG1713</a></td>
<td>
T
R
</td>
<td>Diadenosine tetraphosphatase YqeK or a related HD superfamily phosphohydrolase</td>
</tr>
<tr>
<td>306</td>
<td>493</td>
<td><a href="/research/cog/cog/COG1719/">COG1719</a></td>
<td>
R
</td>
<td>Predicted hydrocarbon binding protein, contains 4VR domain</td>
</tr>
<tr>
<td>1628</td>
<td>3909</td>
<td><a href="/research/cog/cog/COG1721/">COG1721</a></td>
<td>
R
</td>
<td>Uncharacterized membrane-anchored protein with extracellular vWFA and Ig-like domains, component of a predicted archaeal secretion system</td>
</tr>
<tr>
<td>516</td>
<td>1074</td>
<td><a href="/research/cog/cog/COG1724/">COG1724</a></td>
<td>
R
</td>
<td>Predicted RNA binding protein YcfA, dsRBD-like fold, HicA-like mRNA interferase family</td>
</tr>
<tr>
<td>275</td>
<td>354</td>
<td><a href="/research/cog/cog/COG1735/">COG1735</a></td>
<td>
R
</td>
<td>Predicted metal-dependent hydrolase, phosphotriesterase family</td>
</tr>
<tr>
<td>1310</td>
<td>1313</td>
<td><a href="/research/cog/cog/COG1739/">COG1739</a></td>
<td>
R
</td>
<td>Putative translation regulator, IMPACT (imprinted ancient) protein family</td>
</tr>
<tr>
<td>1380</td>
<td>2715</td>
<td><a href="/research/cog/cog/COG1741/">COG1741</a></td>
<td>
R
</td>
<td>Redox-sensitive bicupin YhaK, pirin superfamily</td>
</tr>
<tr>
<td>508</td>
<td>558</td>
<td><a href="/research/cog/cog/COG1742/">COG1742</a></td>
<td>
R
</td>
<td>Uncharacterized inner membrane protein YnfA, drug/metabolite transporter superfamily</td>
</tr>
<tr>
<td>81</td>
<td>98</td>
<td><a href="/research/cog/cog/COG1750/">COG1750</a></td>
<td>
R
</td>
<td>Predicted archaeal serine protease, S18 family</td>
</tr>
<tr>
<td>1478</td>
<td>3417</td>
<td><a href="/research/cog/cog/COG1752/">COG1752</a></td>
<td>
R
</td>
<td>Predicted acylesterase/phospholipase RssA, containd patatin domain</td>
</tr>
<tr>
<td>1387</td>
<td>2403</td>
<td><a href="/research/cog/cog/COG1765/">COG1765</a></td>
<td>
R
</td>
<td>Uncharacterized OsmC-related protein/domain</td>
</tr>
<tr>
<td>175</td>
<td>177</td>
<td><a href="/research/cog/cog/COG1768/">COG1768</a></td>
<td>
R
</td>
<td>Predicted phosphohydrolase, DR1119 family, metallophosphatase superfamily</td>
</tr>
<tr>
<td>957</td>
<td>1046</td>
<td><a href="/research/cog/cog/COG1778/">COG1778</a></td>
<td>
M
R
</td>
<td>3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases</td>
</tr>
<tr>
<td>92</td>
<td>92</td>
<td><a href="/research/cog/cog/COG1779/">COG1779</a></td>
<td>
R
</td>
<td>C4-type Zn-finger protein</td>
</tr>
<tr>
<td>124</td>
<td>126</td>
<td><a href="/research/cog/cog/COG1784/">COG1784</a></td>
<td>
R
</td>
<td>TctA family transporter</td>
</tr>
<tr>
<td>707</td>
<td>890</td>
<td><a href="/research/cog/cog/COG1785/">COG1785</a></td>
<td>
P
R
</td>
<td>Alkaline phosphatase</td>
</tr>
<tr>
<td>13</td>
<td>18</td>
<td><a href="/research/cog/cog/COG1800/">COG1800</a></td>
<td>
R
</td>
<td>Predicted transglutaminase-like protease, UPF0252 family</td>
</tr>
<tr>
<td>942</td>
<td>1302</td>
<td><a href="/research/cog/cog/COG1801/">COG1801</a></td>
<td>
R
</td>
<td>Sugar isomerase-related protein YecE, UPF0759/DUF72 family</td>
</tr>
<tr>
<td>150</td>
<td>212</td>
<td><a href="/research/cog/cog/COG1817/">COG1817</a></td>
<td>
R
</td>
<td>Predicted glycosyltransferase DUF354 family</td>
</tr>
<tr>
<td>133</td>
<td>133</td>
<td><a href="/research/cog/cog/COG1831/">COG1831</a></td>
<td>
R
</td>
<td>Predicted metal-dependent hydrolase, urease superfamily</td>
</tr>
<tr>
<td>1127</td>
<td>1205</td>
<td><a href="/research/cog/cog/COG1832/">COG1832</a></td>
<td>
R
</td>
<td>Predicted CoA-binding protein</td>
</tr>
<tr>
<td>252</td>
<td>254</td>
<td><a href="/research/cog/cog/COG1833/">COG1833</a></td>
<td>
R
</td>
<td>Uri superfamily endonuclease</td>
</tr>
<tr>
<td>326</td>
<td>327</td>
<td><a href="/research/cog/cog/COG1836/">COG1836</a></td>
<td>
R
</td>
<td>Cytidylyltransferase family enzyme</td>
</tr>
<tr>
<td>958</td>
<td>1000</td>
<td><a href="/research/cog/cog/COG1837/">COG1837</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein YlqC, contains KH domain, UPF0109 family</td>
</tr>
<tr>
<td>913</td>
<td>970</td>
<td><a href="/research/cog/cog/COG1847/">COG1847</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein Jag (SpoIIIJ-associated), conains KH and R3H domains</td>
</tr>
<tr>
<td>200</td>
<td>219</td>
<td><a href="/research/cog/cog/COG1852/">COG1852</a></td>
<td>
R
</td>
<td>Predicted redox protein with CxxCxxC motif, DUF116 family</td>
</tr>
<tr>
<td>88</td>
<td>98</td>
<td><a href="/research/cog/cog/COG1856/">COG1856</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, radical SAM superfamily</td>
</tr>
<tr>
<td>500</td>
<td>830</td>
<td><a href="/research/cog/cog/COG1873/">COG1873</a></td>
<td>
R
</td>
<td>Sporulation protein YlmC, YlmC/YmxH family, contains PRC-barrel domain</td>
</tr>
<tr>
<td>847</td>
<td>882</td>
<td><a href="/research/cog/cog/COG1875/">COG1875</a></td>
<td>
R
</td>
<td>Predicted ribonuclease YlaK, contains NYN-type RNase and PhoH-family ATPase domains</td>
</tr>
<tr>
<td>935</td>
<td>1216</td>
<td><a href="/research/cog/cog/COG1881/">COG1881</a></td>
<td>
R
</td>
<td>Uncharacterized protein, putative kinase inhibitor, PEBP/RKIP/YbhB/UPF0098 family</td>
</tr>
<tr>
<td>896</td>
<td>1152</td>
<td><a href="/research/cog/cog/COG1896/">COG1896</a></td>
<td>
F
R
</td>
<td>5&#x27;-deoxynucleotidase YfbR and related HD superfamily hydrolases</td>
</tr>
<tr>
<td>93</td>
<td>104</td>
<td><a href="/research/cog/cog/COG1906/">COG1906</a></td>
<td>
R
</td>
<td>Predicted GntP-related membrane permease AF0261, DUF401 family</td>
</tr>
<tr>
<td>1853</td>
<td>6942</td>
<td><a href="/research/cog/cog/COG1917/">COG1917</a></td>
<td>
R
</td>
<td>Cupin domain protein related to quercetin dioxygenase</td>
</tr>
<tr>
<td>517</td>
<td>626</td>
<td><a href="/research/cog/cog/COG1926/">COG1926</a></td>
<td>
R
</td>
<td>Predicted phosphoribosyltransferase</td>
</tr>
<tr>
<td>148</td>
<td>149</td>
<td><a href="/research/cog/cog/COG1931/">COG1931</a></td>
<td>
R
</td>
<td>Predicted RNA binding protein with dsRBD fold, UPF0201 family</td>
</tr>
<tr>
<td>338</td>
<td>485</td>
<td><a href="/research/cog/cog/COG1938/">COG1938</a></td>
<td>
R
</td>
<td>Predicted ATP-dependent carboligase, ATP-grasp superfamily</td>
</tr>
<tr>
<td>351</td>
<td>388</td>
<td><a href="/research/cog/cog/COG1963/">COG1963</a></td>
<td>
R
</td>
<td>Acid phosphatase family membrane protein YuiD</td>
</tr>
<tr>
<td>155</td>
<td>163</td>
<td><a href="/research/cog/cog/COG1978/">COG1978</a></td>
<td>
R
</td>
<td>Predicted RNase H-related nuclease YkuK, DUF458 family</td>
</tr>
<tr>
<td>599</td>
<td>748</td>
<td><a href="/research/cog/cog/COG1988/">COG1988</a></td>
<td>
R
</td>
<td>Membrane-bound metal-dependent hydrolase YbcI, DUF457 family</td>
</tr>
<tr>
<td>59</td>
<td>64</td>
<td><a href="/research/cog/cog/COG2000/">COG2000</a></td>
<td>
R
</td>
<td>Uncharacterized Fe-S cluster-containing protein</td>
</tr>
<tr>
<td>6</td>
<td>8</td>
<td><a href="/research/cog/cog/COG2028/">COG2028</a></td>
<td>
R
</td>
<td>ASCH domain, putative RNA-binding protein, DUF365 family</td>
</tr>
<tr>
<td>283</td>
<td>375</td>
<td><a href="/research/cog/cog/COG2044/">COG2044</a></td>
<td>
R
</td>
<td>Predicted peroxiredoxin, DsrE/DsrF-like family</td>
</tr>
<tr>
<td>239</td>
<td>266</td>
<td><a href="/research/cog/cog/COG2047/">COG2047</a></td>
<td>
R
</td>
<td>Proteasome assembly chaperone (PAC2) family protein</td>
</tr>
<tr>
<td>283</td>
<td>292</td>
<td><a href="/research/cog/cog/COG2061/">COG2061</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains ACT domain</td>
</tr>
<tr>
<td>1446</td>
<td>2982</td>
<td><a href="/research/cog/cog/COG2070/">COG2070</a></td>
<td>
R
</td>
<td>NAD(P)H-dependent flavin oxidoreductase YrpB, nitropropane dioxygenase family</td>
</tr>
<tr>
<td>590</td>
<td>618</td>
<td><a href="/research/cog/cog/COG2078/">COG2078</a></td>
<td>
R
</td>
<td>Predicted RNA modification protein, AMMECR1 domain</td>
</tr>
<tr>
<td>1391</td>
<td>1833</td>
<td><a href="/research/cog/cog/COG2081/">COG2081</a></td>
<td>
R
</td>
<td>Predicted flavoprotein YhiN</td>
</tr>
<tr>
<td>603</td>
<td>986</td>
<td><a href="/research/cog/cog/COG2085/">COG2085</a></td>
<td>
R
</td>
<td>Predicted dinucleotide-binding enzyme</td>
</tr>
<tr>
<td>51</td>
<td>52</td>
<td><a href="/research/cog/cog/COG2100/">COG2100</a></td>
<td>
R
</td>
<td>Uncharacterized Fe-S cluster-containing enzyme, radical SAM superfamily</td>
</tr>
<tr>
<td>124</td>
<td>124</td>
<td><a href="/research/cog/cog/COG2106/">COG2106</a></td>
<td>
R
</td>
<td>Predicted RNA methylase MTH1, SPOUT superfamily</td>
</tr>
<tr>
<td>191</td>
<td>199</td>
<td><a href="/research/cog/cog/COG2118/">COG2118</a></td>
<td>
R
</td>
<td>DNA-binding TFAR19-related protein, PDSD5 family</td>
</tr>
<tr>
<td>612</td>
<td>758</td>
<td><a href="/research/cog/cog/COG2119/">COG2119</a></td>
<td>
R
</td>
<td>Putative Ca2+/H+ antiporter, TMEM165/GDT1 family</td>
</tr>
<tr>
<td>585</td>
<td>806</td>
<td><a href="/research/cog/cog/COG2129/">COG2129</a></td>
<td>
R
</td>
<td>Predicted phosphoesterase, related to the Icc protein</td>
</tr>
<tr>
<td>678</td>
<td>927</td>
<td><a href="/research/cog/cog/COG2130/">COG2130</a></td>
<td>
Q
R
</td>
<td>NADPH-dependent curcumin reductase CurA</td>
</tr>
<tr>
<td>1245</td>
<td>8519</td>
<td><a href="/research/cog/cog/COG2141/">COG2141</a></td>
<td>
H
R
</td>
<td>Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase)</td>
</tr>
<tr>
<td>164</td>
<td>176</td>
<td><a href="/research/cog/cog/COG2144/">COG2144</a></td>
<td>
R
</td>
<td>Selenophosphate synthetase-related protein</td>
</tr>
<tr>
<td>130</td>
<td>139</td>
<td><a href="/research/cog/cog/COG2150/">COG2150</a></td>
<td>
R
</td>
<td>Predicted regulator of amino acid metabolism, contains ACT domain</td>
</tr>
<tr>
<td>1196</td>
<td>1739</td>
<td><a href="/research/cog/cog/COG2153/">COG2153</a></td>
<td>
R
</td>
<td>Predicted N-acyltransferase, GNAT family</td>
</tr>
<tr>
<td>132</td>
<td>140</td>
<td><a href="/research/cog/cog/COG2158/">COG2158</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains a Zn-finger-like domain</td>
</tr>
<tr>
<td>94</td>
<td>105</td>
<td><a href="/research/cog/cog/COG2164/">COG2164</a></td>
<td>
R
</td>
<td>Uncharacterized protein with cyclophilin fold, contains DUF369 domain</td>
</tr>
<tr>
<td>421</td>
<td>456</td>
<td><a href="/research/cog/cog/COG2187/">COG2187</a></td>
<td>
R
</td>
<td>Aminoglycoside phosphotransferase family enzyme</td>
</tr>
<tr>
<td>385</td>
<td>546</td>
<td><a href="/research/cog/cog/COG2192/">COG2192</a></td>
<td>
R
</td>
<td>Predicted carbamoyl transferase, NodU family</td>
</tr>
<tr>
<td>68</td>
<td>74</td>
<td><a href="/research/cog/cog/COG2248/">COG2248</a></td>
<td>
R
</td>
<td>Predicted hydrolase, metallo-beta-lactamase superfamily</td>
</tr>
<tr>
<td>850</td>
<td>1502</td>
<td><a href="/research/cog/cog/COG2249/">COG2249</a></td>
<td>
R
</td>
<td>Putative NADPH-quinone reductase (modulator of drug activity B)</td>
</tr>
<tr>
<td>310</td>
<td>350</td>
<td><a href="/research/cog/cog/COG2251/">COG2251</a></td>
<td>
R
</td>
<td>Predicted nuclease, RecB family</td>
</tr>
<tr>
<td>823</td>
<td>1154</td>
<td><a href="/research/cog/cog/COG2261/">COG2261</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein YeaQ/YmgE, transglycosylase-associated protein family</td>
</tr>
<tr>
<td>246</td>
<td>261</td>
<td><a href="/research/cog/cog/COG2263/">COG2263</a></td>
<td>
R
</td>
<td>Predicted RNA methylase</td>
</tr>
<tr>
<td>669</td>
<td>797</td>
<td><a href="/research/cog/cog/COG2268/">COG2268</a></td>
<td>
R
</td>
<td>Flotillin family membrane protein YqiK, contains Band7/PHB/SPFH domain</td>
</tr>
<tr>
<td>960</td>
<td>1084</td>
<td><a href="/research/cog/cog/COG2270/">COG2270</a></td>
<td>
R
</td>
<td>MFS-type transporter involved in bile tolerance, Atg22 family</td>
</tr>
<tr>
<td>1147</td>
<td>3832</td>
<td><a href="/research/cog/cog/COG2303/">COG2303</a></td>
<td>
I
R
</td>
<td>Choline dehydrogenase or related flavoprotein</td>
</tr>
<tr>
<td>607</td>
<td>1004</td>
<td><a href="/research/cog/cog/COG2304/">COG2304</a></td>
<td>
R
</td>
<td>Secreted protein containing bacterial Ig-like domain and vWFA domain</td>
</tr>
<tr>
<td>804</td>
<td>1200</td>
<td><a href="/research/cog/cog/COG2308/">COG2308</a></td>
<td>
R
</td>
<td>Circularly permuted ATP-grasp protein</td>
</tr>
<tr>
<td>418</td>
<td>506</td>
<td><a href="/research/cog/cog/COG2314/">COG2314</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein YozV, TM2 domain, contains pTyr</td>
</tr>
<tr>
<td>368</td>
<td>388</td>
<td><a href="/research/cog/cog/COG2316/">COG2316</a></td>
<td>
R
</td>
<td>Predicted hydrolase, HD superfamily</td>
</tr>
<tr>
<td>731</td>
<td>4172</td>
<td><a href="/research/cog/cog/COG2319/">COG2319</a></td>
<td>
R
</td>
<td>WD40 repeat</td>
</tr>
<tr>
<td>489</td>
<td>627</td>
<td><a href="/research/cog/cog/COG2320/">COG2320</a></td>
<td>
R
</td>
<td>GrpB domain, predicted nucleotidyltransferase, UPF0157 family</td>
</tr>
<tr>
<td>759</td>
<td>944</td>
<td><a href="/research/cog/cog/COG2321/">COG2321</a></td>
<td>
R
</td>
<td>Predicted metalloprotease</td>
</tr>
<tr>
<td>828</td>
<td>1127</td>
<td><a href="/research/cog/cog/COG2331/">COG2331</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>1060</td>
<td>2014</td>
<td><a href="/research/cog/cog/COG2340/">COG2340</a></td>
<td>
D
R
</td>
<td>Spore germination protein YkwD and related proteins with CAP (CSP/antigen 5/PR1) domain</td>
</tr>
<tr>
<td>1099</td>
<td>1551</td>
<td><a href="/research/cog/cog/COG2350/">COG2350</a></td>
<td>
Q
R
</td>
<td>YciI superfamily enzyme, includes 5-CHQ dehydrochlorinase, contains active-site pHis</td>
</tr>
<tr>
<td>1123</td>
<td>2458</td>
<td><a href="/research/cog/cog/COG2353/">COG2353</a></td>
<td>
R
</td>
<td>Polyisoprenoid-binding periplasmic protein YceI</td>
</tr>
<tr>
<td>782</td>
<td>1800</td>
<td><a href="/research/cog/cog/COG2358/">COG2358</a></td>
<td>
R
</td>
<td>TRAP-type uncharacterized transport system, periplasmic component</td>
</tr>
<tr>
<td>484</td>
<td>694</td>
<td><a href="/research/cog/cog/COG2364/">COG2364</a></td>
<td>
R
</td>
<td>Membrane protein possibly involved in the transport of sulfur-containing compounds</td>
</tr>
<tr>
<td>794</td>
<td>1128</td>
<td><a href="/research/cog/cog/COG2373/">COG2373</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family</td>
</tr>
<tr>
<td>770</td>
<td>1065</td>
<td><a href="/research/cog/cog/COG2374/">COG2374</a></td>
<td>
R
</td>
<td>Predicted extracellular nuclease</td>
</tr>
<tr>
<td>52</td>
<td>53</td>
<td><a href="/research/cog/cog/COG2380/">COG2380</a></td>
<td>
R
</td>
<td>NurA-like predicted nuclease, RNAse H fold</td>
</tr>
<tr>
<td>790</td>
<td>1071</td>
<td><a href="/research/cog/cog/COG2388/">COG2388</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase, GNAT superfamily</td>
</tr>
<tr>
<td>583</td>
<td>769</td>
<td><a href="/research/cog/cog/COG2391/">COG2391</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein YedE/YeeE, contains two sulfur transport domains</td>
</tr>
<tr>
<td>69</td>
<td>78</td>
<td><a href="/research/cog/cog/COG2401/">COG2401</a></td>
<td>
R
</td>
<td>ABC-type ATPase fused to a predicted acetyltransferase domain</td>
</tr>
<tr>
<td>225</td>
<td>452</td>
<td><a href="/research/cog/cog/COG2405/">COG2405</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains PIN domain</td>
</tr>
<tr>
<td>421</td>
<td>1439</td>
<td><a href="/research/cog/cog/COG2409/">COG2409</a></td>
<td>
R
</td>
<td>Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily</td>
</tr>
<tr>
<td>80</td>
<td>81</td>
<td><a href="/research/cog/cog/COG2410/">COG2410</a></td>
<td>
R
</td>
<td>Predicted nuclease (RNAse H fold)</td>
</tr>
<tr>
<td>85</td>
<td>100</td>
<td><a href="/research/cog/cog/COG2411/">COG2411</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains PUA-like ASCH domain</td>
</tr>
<tr>
<td>45</td>
<td>47</td>
<td><a href="/research/cog/cog/COG2413/">COG2413</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase</td>
</tr>
<tr>
<td>159</td>
<td>162</td>
<td><a href="/research/cog/cog/COG2433/">COG2433</a></td>
<td>
R
</td>
<td>Possible nuclease of RNase H fold, RuvC/YqgF family</td>
</tr>
<tr>
<td>39</td>
<td>41</td>
<td><a href="/research/cog/cog/COG2441/">COG2441</a></td>
<td>
R
</td>
<td>Predicted butyrate kinase, DUF1464 family</td>
</tr>
<tr>
<td>344</td>
<td>516</td>
<td><a href="/research/cog/cog/COG2445/">COG2445</a></td>
<td>
R
</td>
<td>Uncharacterized HEPN domain protein YutE, UPF0331/DUF86 family</td>
</tr>
<tr>
<td>87</td>
<td>88</td>
<td><a href="/research/cog/cog/COG2454/">COG2454</a></td>
<td>
R
</td>
<td>Predicted nuclease, contains PIN domain</td>
</tr>
<tr>
<td>239</td>
<td>281</td>
<td><a href="/research/cog/cog/COG2461/">COG2461</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein AF0170, contains SAB, hemerythrin HHE, and PAS domains</td>
</tr>
<tr>
<td>802</td>
<td>959</td>
<td><a href="/research/cog/cog/COG2509/">COG2509</a></td>
<td>
R
</td>
<td>FAD-dependent dehydrogenase</td>
</tr>
<tr>
<td>209</td>
<td>573</td>
<td><a href="/research/cog/cog/COG2512/">COG2512</a></td>
<td>
R
</td>
<td>Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain</td>
</tr>
<tr>
<td>220</td>
<td>245</td>
<td><a href="/research/cog/cog/COG2516/">COG2516</a></td>
<td>
R
</td>
<td>Biotin synthase-related protein, radical SAM superfamily</td>
</tr>
<tr>
<td>23</td>
<td>24</td>
<td><a href="/research/cog/cog/COG2517/">COG2517</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains C-terminal EMAP domain</td>
</tr>
<tr>
<td>242</td>
<td>288</td>
<td><a href="/research/cog/cog/COG2605/">COG2605</a></td>
<td>
R
</td>
<td>Predicted kinase related to galactokinase and mevalonate kinase</td>
</tr>
<tr>
<td>703</td>
<td>715</td>
<td><a href="/research/cog/cog/COG2607/">COG2607</a></td>
<td>
R
</td>
<td>Predicted ATPase, AAA+ superfamily</td>
</tr>
<tr>
<td>454</td>
<td>460</td>
<td><a href="/research/cog/cog/COG2715/">COG2715</a></td>
<td>
R
</td>
<td>Spore maturation protein SpmA (function unknown)</td>
</tr>
<tr>
<td>576</td>
<td>592</td>
<td><a href="/research/cog/cog/COG2718/">COG2718</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YeaH/YhbH, required for sporulation, DUF444 family</td>
</tr>
<tr>
<td>566</td>
<td>978</td>
<td><a href="/research/cog/cog/COG2819/">COG2819</a></td>
<td>
R
</td>
<td>Predicted hydrolase of the alpha/beta superfamily</td>
</tr>
<tr>
<td>868</td>
<td>896</td>
<td><a href="/research/cog/cog/COG2824/">COG2824</a></td>
<td>
R
</td>
<td>Uncharacterized Zn-ribbon-containing protein</td>
</tr>
<tr>
<td>37</td>
<td>91</td>
<td><a href="/research/cog/cog/COG2880/">COG2880</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein, potential antitoxin AbrB/MazE fold</td>
</tr>
<tr>
<td>83</td>
<td>109</td>
<td><a href="/research/cog/cog/COG2881/">COG2881</a></td>
<td>
R
</td>
<td>GTPase-interacting Yip1 domain</td>
</tr>
<tr>
<td>159</td>
<td>308</td>
<td><a href="/research/cog/cog/COG2886/">COG2886</a></td>
<td>
R
</td>
<td>Predicted antitoxin, contains HTH domain</td>
</tr>
<tr>
<td>306</td>
<td>372</td>
<td><a href="/research/cog/cog/COG2888/">COG2888</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein involved in translation, contains Zn-ribbon domain, DUF1610 family</td>
</tr>
<tr>
<td>574</td>
<td>662</td>
<td><a href="/research/cog/cog/COG2907/">COG2907</a></td>
<td>
R
</td>
<td>Predicted flavin-containing amine oxidase</td>
</tr>
<tr>
<td>662</td>
<td>1010</td>
<td><a href="/research/cog/cog/COG2910/">COG2910</a></td>
<td>
R
</td>
<td>Putative NADH-flavin reductase</td>
</tr>
<tr>
<td>736</td>
<td>1355</td>
<td><a href="/research/cog/cog/COG2936/">COG2936</a></td>
<td>
R
</td>
<td>Predicted acyl esterase</td>
</tr>
<tr>
<td>793</td>
<td>904</td>
<td><a href="/research/cog/cog/COG2945/">COG2945</a></td>
<td>
R
</td>
<td>Alpha/beta superfamily hydrolase</td>
</tr>
<tr>
<td>780</td>
<td>795</td>
<td><a href="/research/cog/cog/COG2947/">COG2947</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains EVE domain</td>
</tr>
<tr>
<td>500</td>
<td>526</td>
<td><a href="/research/cog/cog/COG2954/">COG2954</a></td>
<td>
R
</td>
<td>CYTH domain, found in class IV adenylate cyclase and various triphosphatases</td>
</tr>
<tr>
<td>81</td>
<td>83</td>
<td><a href="/research/cog/cog/COG2958/">COG2958</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, HrgA family, contains HARE-HTH domain</td>
</tr>
<tr>
<td>416</td>
<td>417</td>
<td><a href="/research/cog/cog/COG2959/">COG2959</a></td>
<td>
R
</td>
<td>Proteobacterial HemX domain, involved in 2-ketogluconate production (unrelated to B. subtilis HemX, COG0755, no evidence of involvement in heme biosynthesis)</td>
</tr>
<tr>
<td>874</td>
<td>994</td>
<td><a href="/research/cog/cog/COG2962/">COG2962</a></td>
<td>
R
</td>
<td>Membrane protein RarD, contains two EamA domains, drug/metabolite transporter family</td>
</tr>
<tr>
<td>967</td>
<td>1094</td>
<td><a href="/research/cog/cog/COG2968/">COG2968</a></td>
<td>
R
</td>
<td>Oxidative stress-related protein YggE, contains kinase-interacting SIMPL domain</td>
</tr>
<tr>
<td>553</td>
<td>559</td>
<td><a href="/research/cog/cog/COG2983/">COG2983</a></td>
<td>
R
</td>
<td>Uncharacterized cysteine cluster protein YcgN, CxxCxxCC family</td>
</tr>
<tr>
<td>734</td>
<td>1407</td>
<td><a href="/research/cog/cog/COG2984/">COG2984</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, periplasmic component</td>
</tr>
<tr>
<td>385</td>
<td>536</td>
<td><a href="/research/cog/cog/COG2985/">COG2985</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein YbjL, putative transporter</td>
</tr>
<tr>
<td>214</td>
<td>257</td>
<td><a href="/research/cog/cog/COG2992/">COG2992</a></td>
<td>
R
</td>
<td>Uncharacterized FlgJ-related protein</td>
</tr>
<tr>
<td>569</td>
<td>572</td>
<td><a href="/research/cog/cog/COG2996/">COG2996</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein YitL, contains S1 domains, virulence factor B family</td>
</tr>
<tr>
<td>827</td>
<td>989</td>
<td><a href="/research/cog/cog/COG3011/">COG3011</a></td>
<td>
R
</td>
<td>Predicted thiol-disulfide oxidoreductase YuxK, DCC family</td>
</tr>
<tr>
<td>437</td>
<td>476</td>
<td><a href="/research/cog/cog/COG3016/">COG3016</a></td>
<td>
R
</td>
<td>Putative heme-binding protein PhuW, contains EreA/ChaN-like domain</td>
</tr>
<tr>
<td>582</td>
<td>745</td>
<td><a href="/research/cog/cog/COG3021/">COG3021</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YafD, endonuclease/exonuclease/phosphatase (EEP) superfamily</td>
</tr>
<tr>
<td>841</td>
<td>845</td>
<td><a href="/research/cog/cog/COG3030/">COG3030</a></td>
<td>
R
</td>
<td>FxsA protein affecting phage T7 exclusion by the F plasmid, UPF0716 family</td>
</tr>
<tr>
<td>150</td>
<td>191</td>
<td><a href="/research/cog/cog/COG3042/">COG3042</a></td>
<td>
R
</td>
<td>Putative hemolysin</td>
</tr>
<tr>
<td>209</td>
<td>212</td>
<td><a href="/research/cog/cog/COG3044/">COG3044</a></td>
<td>
R
</td>
<td>Predicted ATPase of the ABC class</td>
</tr>
<tr>
<td>521</td>
<td>527</td>
<td><a href="/research/cog/cog/COG3046/">COG3046</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein related to deoxyribodipyrimidine photolyase</td>
</tr>
<tr>
<td>418</td>
<td>578</td>
<td><a href="/research/cog/cog/COG3049/">COG3049</a></td>
<td>
M
R
</td>
<td>Penicillin V acylase or related amidase, Ntn superfamily</td>
</tr>
<tr>
<td>100</td>
<td>116</td>
<td><a href="/research/cog/cog/COG3054/">COG3054</a></td>
<td>
R
</td>
<td>Predicted transcriptional regulator YtfJ</td>
</tr>
<tr>
<td>154</td>
<td>166</td>
<td><a href="/research/cog/cog/COG3085/">COG3085</a></td>
<td>
R
</td>
<td>Uncharacterized RNA-binding protein YifE, UPF0438 family</td>
</tr>
<tr>
<td>393</td>
<td>408</td>
<td><a href="/research/cog/cog/COG3091/">COG3091</a></td>
<td>
R
</td>
<td>Predicted Zn-dependent metalloprotease, SprT family</td>
</tr>
<tr>
<td>104</td>
<td>104</td>
<td><a href="/research/cog/cog/COG3102/">COG3102</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YecM, predicted metalloenzyme</td>
</tr>
<tr>
<td>681</td>
<td>1107</td>
<td><a href="/research/cog/cog/COG3103/">COG3103</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YgiM, contains N-terminal SH3 domain, DUF1202 family</td>
</tr>
<tr>
<td>159</td>
<td>228</td>
<td><a href="/research/cog/cog/COG3111/">COG3111</a></td>
<td>
R
</td>
<td>Predicted periplasmic protein with OB-fold, involved in stress response, YdeI/OmdA family</td>
</tr>
<tr>
<td>437</td>
<td>557</td>
<td><a href="/research/cog/cog/COG3128/">COG3128</a></td>
<td>
R
</td>
<td>Predicted 2-oxoglutarate- and Fe(II)-dependent dioxygenase YbiX</td>
</tr>
<tr>
<td>683</td>
<td>743</td>
<td><a href="/research/cog/cog/COG3146/">COG3146</a></td>
<td>
R
</td>
<td>Putative amidoligase,GNAT N-acyltransferase family</td>
</tr>
<tr>
<td>402</td>
<td>481</td>
<td><a href="/research/cog/cog/COG3150/">COG3150</a></td>
<td>
R
</td>
<td>Predicted esterase YcpF, UPF0227 family</td>
</tr>
<tr>
<td>1344</td>
<td>2755</td>
<td><a href="/research/cog/cog/COG3153/">COG3153</a></td>
<td>
R
</td>
<td>Predicted N-acetyltransferase YhbS</td>
</tr>
<tr>
<td>944</td>
<td>2283</td>
<td><a href="/research/cog/cog/COG3173/">COG3173</a></td>
<td>
R
</td>
<td>Predicted kinase, aminoglycoside phosphotransferase (APT) family</td>
</tr>
<tr>
<td>824</td>
<td>1143</td>
<td><a href="/research/cog/cog/COG3176/">COG3176</a></td>
<td>
R
</td>
<td>GNAT family N-acetyltransferase domain</td>
</tr>
<tr>
<td>742</td>
<td>748</td>
<td><a href="/research/cog/cog/COG3178/">COG3178</a></td>
<td>
R
</td>
<td>N-acetylmuramate/N-acetylglucosamine kinase, aminoglycoside/choline kinase (APH/ChoK) family</td>
</tr>
<tr>
<td>473</td>
<td>618</td>
<td><a href="/research/cog/cog/COG3180/">COG3180</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein AbrB, regulator of aidB expression</td>
</tr>
<tr>
<td>1033</td>
<td>1468</td>
<td><a href="/research/cog/cog/COG3185/">COG3185</a></td>
<td>
E
R
</td>
<td>4-hydroxyphenylpyruvate dioxygenase and related hemolysins</td>
</tr>
<tr>
<td>48</td>
<td>51</td>
<td><a href="/research/cog/cog/COG3196/">COG3196</a></td>
<td>
R
</td>
<td>Colicin E2 tolerance protein CbrC, UPF0167 family</td>
</tr>
<tr>
<td>150</td>
<td>186</td>
<td><a href="/research/cog/cog/COG3204/">COG3204</a></td>
<td>
R
</td>
<td>Uncharacterized Ca-binding beta-propeller protein YjiK</td>
</tr>
<tr>
<td>717</td>
<td>2583</td>
<td><a href="/research/cog/cog/COG3209/">COG3209</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein RhsA, contains RHS repeats</td>
</tr>
<tr>
<td>700</td>
<td>971</td>
<td><a href="/research/cog/cog/COG3211/">COG3211</a></td>
<td>
R
</td>
<td>Secreted phosphatase, PhoX family</td>
</tr>
<tr>
<td>368</td>
<td>379</td>
<td><a href="/research/cog/cog/COG3218/">COG3218</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, auxiliary component</td>
</tr>
<tr>
<td>163</td>
<td>169</td>
<td><a href="/research/cog/cog/COG3223/">COG3223</a></td>
<td>
R
</td>
<td>Phosphate starvation-inducible membrane PsiE (function unknown)</td>
</tr>
<tr>
<td>242</td>
<td>292</td>
<td><a href="/research/cog/cog/COG3224/">COG3224</a></td>
<td>
R
</td>
<td>Antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme</td>
</tr>
<tr>
<td>120</td>
<td>128</td>
<td><a href="/research/cog/cog/COG3233/">COG3233</a></td>
<td>
R
</td>
<td>Predicted deacetylase</td>
</tr>
<tr>
<td>173</td>
<td>173</td>
<td><a href="/research/cog/cog/COG3235/">COG3235</a></td>
<td>
R
</td>
<td>Uncharacterized CbiM-related membrane protein</td>
</tr>
<tr>
<td>907</td>
<td>1325</td>
<td><a href="/research/cog/cog/COG3237/">COG3237</a></td>
<td>
R
</td>
<td>Uncharacterized ProP-interacting protein YjbJ, UPF0337 family</td>
</tr>
<tr>
<td>673</td>
<td>854</td>
<td><a href="/research/cog/cog/COG3247/">COG3247</a></td>
<td>
R
</td>
<td>Acid resistance membrane protein HdeD, DUF308 family</td>
</tr>
<tr>
<td>172</td>
<td>507</td>
<td><a href="/research/cog/cog/COG3269/">COG3269</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein, contains TRAM domain</td>
</tr>
<tr>
<td>250</td>
<td>323</td>
<td><a href="/research/cog/cog/COG3273/">COG3273</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains PhoU and TrkA_C domains</td>
</tr>
<tr>
<td>196</td>
<td>206</td>
<td><a href="/research/cog/cog/COG3294/">COG3294</a></td>
<td>
R
</td>
<td>Metal-dependent phosphatase/phosphodiesterase, HD supefamily</td>
</tr>
<tr>
<td>426</td>
<td>563</td>
<td><a href="/research/cog/cog/COG3296/">COG3296</a></td>
<td>
R
</td>
<td>Uncharacterized Tic20-related protein, DUF4870 domain</td>
</tr>
<tr>
<td>537</td>
<td>724</td>
<td><a href="/research/cog/cog/COG3313/">COG3313</a></td>
<td>
R
</td>
<td>Predicted Fe-S protein YdhL, DUF1289 family</td>
</tr>
<tr>
<td>618</td>
<td>631</td>
<td><a href="/research/cog/cog/COG3323/">COG3323</a></td>
<td>
R
</td>
<td>PII-like insert in the global regulator YqfO, YbgI/NIF3 family</td>
</tr>
<tr>
<td>1109</td>
<td>2937</td>
<td><a href="/research/cog/cog/COG3324/">COG3324</a></td>
<td>
R
</td>
<td>Lactoylglutathione lyase-related enzyme, vicinal oxygen chelate (VOC) family</td>
</tr>
<tr>
<td>229</td>
<td>244</td>
<td><a href="/research/cog/cog/COG3331/">COG3331</a></td>
<td>
R
</td>
<td>Penicillin-binding protein-related factor A, putative recombinase</td>
</tr>
<tr>
<td>457</td>
<td>459</td>
<td><a href="/research/cog/cog/COG3332/">COG3332</a></td>
<td>
R
</td>
<td>Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, contains NRDE motif</td>
</tr>
<tr>
<td>584</td>
<td>1809</td>
<td><a href="/research/cog/cog/COG3333/">COG3333</a></td>
<td>
R
</td>
<td>TctA family transporter</td>
</tr>
<tr>
<td>233</td>
<td>241</td>
<td><a href="/research/cog/cog/COG3341/">COG3341</a></td>
<td>
R
</td>
<td>Ribonuclease HI-related protein, contains viroplasmin and RNaseH domains</td>
</tr>
<tr>
<td>400</td>
<td>492</td>
<td><a href="/research/cog/cog/COG3342/">COG3342</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, Ntn-hydrolase superfamily</td>
</tr>
<tr>
<td>414</td>
<td>636</td>
<td><a href="/research/cog/cog/COG3349/">COG3349</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster</td>
</tr>
<tr>
<td>378</td>
<td>403</td>
<td><a href="/research/cog/cog/COG3359/">COG3359</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YprB, contains RNaseH-like and TPR domains</td>
</tr>
<tr>
<td>523</td>
<td>621</td>
<td><a href="/research/cog/cog/COG3360/">COG3360</a></td>
<td>
R
</td>
<td>Flavin-binding protein dodecin</td>
</tr>
<tr>
<td>104</td>
<td>105</td>
<td><a href="/research/cog/cog/COG3364/">COG3364</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>390</td>
<td>449</td>
<td><a href="/research/cog/cog/COG3367/">COG3367</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, NAD-dependent epimerase/dehydratase family</td>
</tr>
<tr>
<td>15</td>
<td>17</td>
<td><a href="/research/cog/cog/COG3368/">COG3368</a></td>
<td>
R
</td>
<td>Predicted permease</td>
</tr>
<tr>
<td>116</td>
<td>150</td>
<td><a href="/research/cog/cog/COG3370/">COG3370</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein AF1964, DsrE/DsrF-like family</td>
</tr>
<tr>
<td>194</td>
<td>221</td>
<td><a href="/research/cog/cog/COG3372/">COG3372</a></td>
<td>
R
</td>
<td>Predicted nuclease of restriction endonuclease-like (RecB) superfamily, implicated in nucleotide excision repair</td>
</tr>
<tr>
<td>149</td>
<td>179</td>
<td><a href="/research/cog/cog/COG3375/">COG3375</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase, GNAT superfamily</td>
</tr>
<tr>
<td>247</td>
<td>508</td>
<td><a href="/research/cog/cog/COG3379/">COG3379</a></td>
<td>
R
</td>
<td>Predicted phosphohydrolase or phosphomutase, AlkP superfamily</td>
</tr>
<tr>
<td>361</td>
<td>379</td>
<td><a href="/research/cog/cog/COG3380/">COG3380</a></td>
<td>
R
</td>
<td>Predicted NAD/FAD-dependent oxidoreductase</td>
</tr>
<tr>
<td>334</td>
<td>398</td>
<td><a href="/research/cog/cog/COG3382/">COG3382</a></td>
<td>
R
</td>
<td>B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase)</td>
</tr>
<tr>
<td>1110</td>
<td>2900</td>
<td><a href="/research/cog/cog/COG3391/">COG3391</a></td>
<td>
R
</td>
<td>DNA-binding beta-propeller fold protein YncE</td>
</tr>
<tr>
<td>664</td>
<td>1128</td>
<td><a href="/research/cog/cog/COG3393/">COG3393</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase, GNAT family</td>
</tr>
<tr>
<td>160</td>
<td>328</td>
<td><a href="/research/cog/cog/COG3397/">COG3397</a></td>
<td>
R
</td>
<td>Predicted carbohydrate-binding protein, contains CBM5 and CBM33 domains</td>
</tr>
<tr>
<td>259</td>
<td>377</td>
<td><a href="/research/cog/cog/COG3401/">COG3401</a></td>
<td>
R
</td>
<td>Fibronectin type 3 domain</td>
</tr>
<tr>
<td>110</td>
<td>1990</td>
<td><a href="/research/cog/cog/COG3413/">COG3413</a></td>
<td>
R
</td>
<td>Predicted transcriptional regulator, contains HTH domain</td>
</tr>
<tr>
<td>384</td>
<td>590</td>
<td><a href="/research/cog/cog/COG3450/">COG3450</a></td>
<td>
R
</td>
<td>Predicted enzyme of the cupin superfamily</td>
</tr>
<tr>
<td>433</td>
<td>591</td>
<td><a href="/research/cog/cog/COG3453/">COG3453</a></td>
<td>
R
</td>
<td>Predicted phosphohydrolase, protein tyrosine phosphatase (PTP) superfamily, DUF442 family</td>
</tr>
<tr>
<td>99</td>
<td>109</td>
<td><a href="/research/cog/cog/COG3477/">COG3477</a></td>
<td>
R
</td>
<td>Membrane protein YagU involved in acid resistance, DUF1440 family</td>
</tr>
<tr>
<td>141</td>
<td>146</td>
<td><a href="/research/cog/cog/COG3478/">COG3478</a></td>
<td>
R
</td>
<td>Predicted nucleic-acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>381</td>
<td>484</td>
<td><a href="/research/cog/cog/COG3488/">COG3488</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein with two CxxC motifs, DUF1111 family</td>
</tr>
<tr>
<td>314</td>
<td>352</td>
<td><a href="/research/cog/cog/COG3489/">COG3489</a></td>
<td>
R
</td>
<td>Imelysin-like iron-regulated protein IrpA, duplicated M75 peptidase-like domain</td>
</tr>
<tr>
<td>416</td>
<td>499</td>
<td><a href="/research/cog/cog/COG3503/">COG3503</a></td>
<td>
R
</td>
<td>Integral membrane N-acetyltransferase, HGSNAT/DUF1624 family</td>
</tr>
<tr>
<td>326</td>
<td>333</td>
<td><a href="/research/cog/cog/COG3526/">COG3526</a></td>
<td>
R
</td>
<td>Predicted selenoprotein, Rdx family</td>
</tr>
<tr>
<td>186</td>
<td>186</td>
<td><a href="/research/cog/cog/COG3529/">COG3529</a></td>
<td>
R
</td>
<td>Predicted nucleic-acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>558</td>
<td>621</td>
<td><a href="/research/cog/cog/COG3536/">COG3536</a></td>
<td>
R
</td>
<td>Putative dioxygenase with GBBH-like_N/DUF971 domain</td>
</tr>
<tr>
<td>315</td>
<td>412</td>
<td><a href="/research/cog/cog/COG3541/">COG3541</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase YcgL</td>
</tr>
<tr>
<td>514</td>
<td>532</td>
<td><a href="/research/cog/cog/COG3542/">COG3542</a></td>
<td>
R
</td>
<td>Predicted sugar epimerase, cupin superfamily</td>
</tr>
<tr>
<td>435</td>
<td>573</td>
<td><a href="/research/cog/cog/COG3545/">COG3545</a></td>
<td>
R
</td>
<td>Predicted esterase of the alpha/beta hydrolase fold</td>
</tr>
<tr>
<td>160</td>
<td>170</td>
<td><a href="/research/cog/cog/COG3554/">COG3554</a></td>
<td>
R
</td>
<td>Spiral beta-roll protein, possibly glycolipid-binding</td>
</tr>
<tr>
<td>189</td>
<td>207</td>
<td><a href="/research/cog/cog/COG3560/">COG3560</a></td>
<td>
R
</td>
<td>FRM2-like oxidoreductase, nitroreductase family</td>
</tr>
<tr>
<td>387</td>
<td>421</td>
<td><a href="/research/cog/cog/COG3565/">COG3565</a></td>
<td>
R
</td>
<td>Predicted dioxygenase of extradiol dioxygenase family</td>
</tr>
<tr>
<td>1321</td>
<td>2572</td>
<td><a href="/research/cog/cog/COG3568/">COG3568</a></td>
<td>
R
</td>
<td>Metal-dependent hydrolase, endonuclease/exonuclease/phosphatase family</td>
</tr>
<tr>
<td>351</td>
<td>361</td>
<td><a href="/research/cog/cog/COG3571/">COG3571</a></td>
<td>
R
</td>
<td>Predicted hydrolase of the alpha/beta-hydrolase fold</td>
</tr>
<tr>
<td>267</td>
<td>318</td>
<td><a href="/research/cog/cog/COG3573/">COG3573</a></td>
<td>
R
</td>
<td>Predicted oxidoreductase</td>
</tr>
<tr>
<td>195</td>
<td>202</td>
<td><a href="/research/cog/cog/COG3575/">COG3575</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase</td>
</tr>
<tr>
<td>628</td>
<td>977</td>
<td><a href="/research/cog/cog/COG3576/">COG3576</a></td>
<td>
R
</td>
<td>Predicted flavin-nucleotide-binding protein, pyridoxine 5&#x27;-phosphate oxidase superfamily</td>
</tr>
<tr>
<td>566</td>
<td>809</td>
<td><a href="/research/cog/cog/COG3577/">COG3577</a></td>
<td>
R
</td>
<td>Predicted aspartyl protease</td>
</tr>
<tr>
<td>358</td>
<td>495</td>
<td><a href="/research/cog/cog/COG3580/">COG3580</a></td>
<td>
R
</td>
<td>Predicted nucleotide-binding protein, sugar kinase/HSP70/actin superfamily</td>
</tr>
<tr>
<td>353</td>
<td>493</td>
<td><a href="/research/cog/cog/COG3581/">COG3581</a></td>
<td>
R
</td>
<td>Predicted nucleotide-binding protein, sugar kinase/HSP70/actin superfamily</td>
</tr>
<tr>
<td>412</td>
<td>536</td>
<td><a href="/research/cog/cog/COG3583/">COG3583</a></td>
<td>
R
</td>
<td>Putative cell wall-binding protein/resuscitation-promoting factor YabE, contains G5 and DUF348 domains</td>
</tr>
<tr>
<td>128</td>
<td>135</td>
<td><a href="/research/cog/cog/COG3586/">COG3586</a></td>
<td>
R
</td>
<td>Uncharacterized protein domain, C-terminal to COG1479 DNAse/DNA nickase</td>
</tr>
<tr>
<td>280</td>
<td>375</td>
<td><a href="/research/cog/cog/COG3596/">COG3596</a></td>
<td>
R
</td>
<td>Predicted GTPase</td>
</tr>
<tr>
<td>613</td>
<td>884</td>
<td><a href="/research/cog/cog/COG3607/">COG3607</a></td>
<td>
R
</td>
<td>Lactoylglutathione lyase-related enzyme, vicinal oxygen chelate (VOC) family</td>
</tr>
<tr>
<td>822</td>
<td>1478</td>
<td><a href="/research/cog/cog/COG3608/">COG3608</a></td>
<td>
R
</td>
<td>Predicted deacylase</td>
</tr>
<tr>
<td>630</td>
<td>1230</td>
<td><a href="/research/cog/cog/COG3618/">COG3618</a></td>
<td>
R
</td>
<td>Predicted metal-dependent hydrolase, TIM-barrel fold</td>
</tr>
<tr>
<td>245</td>
<td>317</td>
<td><a href="/research/cog/cog/COG3621/">COG3621</a></td>
<td>
R
</td>
<td>Patatin-like phospholipase/acyl hydrolase, includes sporulation protein CotR</td>
</tr>
<tr>
<td>719</td>
<td>1431</td>
<td><a href="/research/cog/cog/COG3631/">COG3631</a></td>
<td>
R
</td>
<td>Ketosteroid isomerase-related protein</td>
</tr>
<tr>
<td>254</td>
<td>271</td>
<td><a href="/research/cog/cog/COG3647/">COG3647</a></td>
<td>
R
</td>
<td>Uncharacterized riboswitch-regulated membrane protein YjdF</td>
</tr>
<tr>
<td>265</td>
<td>278</td>
<td><a href="/research/cog/cog/COG3683/">COG3683</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, periplasmic component</td>
</tr>
<tr>
<td>143</td>
<td>347</td>
<td><a href="/research/cog/cog/COG3687/">COG3687</a></td>
<td>
R
</td>
<td>Predicted metal-dependent hydrolase</td>
</tr>
<tr>
<td>340</td>
<td>441</td>
<td><a href="/research/cog/cog/COG3694/">COG3694</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>64</td>
<td>67</td>
<td><a href="/research/cog/cog/COG3700/">COG3700</a></td>
<td>
P
R
</td>
<td>Acid phosphatase, class B</td>
</tr>
<tr>
<td>93</td>
<td>142</td>
<td><a href="/research/cog/cog/COG3729/">COG3729</a></td>
<td>
R
</td>
<td>General stress protein YciG, contains tandem KGG domains</td>
</tr>
<tr>
<td>342</td>
<td>388</td>
<td><a href="/research/cog/cog/COG3752/">COG3752</a></td>
<td>
R
</td>
<td>Steroid 5-alpha reductase family enzyme</td>
</tr>
<tr>
<td>305</td>
<td>334</td>
<td><a href="/research/cog/cog/COG3760/">COG3760</a></td>
<td>
R
</td>
<td>Predicted aminoacyl-tRNA deacylase, YbaK-like aminoacyl-tRNA editing domain</td>
</tr>
<tr>
<td>479</td>
<td>491</td>
<td><a href="/research/cog/cog/COG3762/">COG3762</a></td>
<td>
R
</td>
<td>TPM domain-containing protein</td>
</tr>
<tr>
<td>443</td>
<td>656</td>
<td><a href="/research/cog/cog/COG3800/">COG3800</a></td>
<td>
R
</td>
<td>Predicted transcriptional regulator</td>
</tr>
<tr>
<td>355</td>
<td>428</td>
<td><a href="/research/cog/cog/COG3809/">COG3809</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-finger domain</td>
</tr>
<tr>
<td>349</td>
<td>350</td>
<td><a href="/research/cog/cog/COG3816/">COG3816</a></td>
<td>
R
</td>
<td>Predicted stress response protein, DUF1285 family</td>
</tr>
<tr>
<td>106</td>
<td>116</td>
<td><a href="/research/cog/cog/COG3818/">COG3818</a></td>
<td>
R
</td>
<td>Predicted N-acetyltransferase, GNAT superfamily</td>
</tr>
<tr>
<td>409</td>
<td>1134</td>
<td><a href="/research/cog/cog/COG3828/">COG3828</a></td>
<td>
R
</td>
<td>Type 1 glutamine amidotransferase (GATase1)-like domain</td>
</tr>
<tr>
<td>261</td>
<td>304</td>
<td><a href="/research/cog/cog/COG3864/">COG3864</a></td>
<td>
R
</td>
<td>Predicted metal-dependent peptidase</td>
</tr>
<tr>
<td>617</td>
<td>767</td>
<td><a href="/research/cog/cog/COG3865/">COG3865</a></td>
<td>
R
</td>
<td>Glyoxalase superfamily enzyme, possible 3-demethylubiquinone-9 3-methyltransferase</td>
</tr>
<tr>
<td>68</td>
<td>75</td>
<td><a href="/research/cog/cog/COG3889/">COG3889</a></td>
<td>
R
</td>
<td>Extracellular solute-binding protein, contains Ig-fold domain</td>
</tr>
<tr>
<td>595</td>
<td>2614</td>
<td><a href="/research/cog/cog/COG3899/">COG3899</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>262</td>
<td>1282</td>
<td><a href="/research/cog/cog/COG3903/">COG3903</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>203</td>
<td>213</td>
<td><a href="/research/cog/cog/COG3907/">COG3907</a></td>
<td>
R
</td>
<td>Membrane-associated enzyme, PAP2 (acid phosphatase) superfamily</td>
</tr>
<tr>
<td>314</td>
<td>355</td>
<td><a href="/research/cog/cog/COG3910/">COG3910</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>258</td>
<td>289</td>
<td><a href="/research/cog/cog/COG3911/">COG3911</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>399</td>
<td>497</td>
<td><a href="/research/cog/cog/COG3919/">COG3919</a></td>
<td>
R
</td>
<td>Predicted ATP-dependent carboligase, ATP-grasp superfamily</td>
</tr>
<tr>
<td>169</td>
<td>187</td>
<td><a href="/research/cog/cog/COG3930/">COG3930</a></td>
<td>
R
</td>
<td>Regulator of flavohemoglobin expression, contains QEGLA motif</td>
</tr>
<tr>
<td>323</td>
<td>415</td>
<td><a href="/research/cog/cog/COG3945/">COG3945</a></td>
<td>
R
</td>
<td>Hemerythrin domain</td>
</tr>
<tr>
<td>294</td>
<td>444</td>
<td><a href="/research/cog/cog/COG3950/">COG3950</a></td>
<td>
R
</td>
<td>Predicted ATP-binding protein involved in virulence</td>
</tr>
<tr>
<td>219</td>
<td>230</td>
<td><a href="/research/cog/cog/COG3952/">COG3952</a></td>
<td>
R
</td>
<td>Uncharacterized N-terminal domain of lipid-A-disaccharide synthase</td>
</tr>
<tr>
<td>1558</td>
<td>1611</td>
<td><a href="/research/cog/cog/COG3956/">COG3956</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YabN, contains tetrapyrrole methylase and MazG-like pyrophosphatase domain</td>
</tr>
<tr>
<td>245</td>
<td>280</td>
<td><a href="/research/cog/cog/COG3961/">COG3961</a></td>
<td>
G
H
R
</td>
<td>TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase</td>
</tr>
<tr>
<td>217</td>
<td>284</td>
<td><a href="/research/cog/cog/COG3964/">COG3964</a></td>
<td>
R
</td>
<td>Predicted amidohydrolase</td>
</tr>
<tr>
<td>69</td>
<td>77</td>
<td><a href="/research/cog/cog/COG3969/">COG3969</a></td>
<td>
R
</td>
<td>Predicted phosphoadenosine phosphosulfate sulfurtransferase, contains C-terminal DUF3440 domain</td>
</tr>
<tr>
<td>313</td>
<td>334</td>
<td><a href="/research/cog/cog/COG3970/">COG3970</a></td>
<td>
R
</td>
<td>Fumarylacetoacetate (FAA) hydrolase family protein</td>
</tr>
<tr>
<td>584</td>
<td>805</td>
<td><a href="/research/cog/cog/COG3975/">COG3975</a></td>
<td>
R
</td>
<td>Predicted metalloprotease, contains C-terminal PDZ domain</td>
</tr>
<tr>
<td>302</td>
<td>614</td>
<td><a href="/research/cog/cog/COG3976/">COG3976</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains FMN-binding domain</td>
</tr>
<tr>
<td>298</td>
<td>375</td>
<td><a href="/research/cog/cog/COG3981/">COG3981</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase</td>
</tr>
<tr>
<td>49</td>
<td>51</td>
<td><a href="/research/cog/cog/COG4002/">COG4002</a></td>
<td>
R
</td>
<td>Predicted methyltransferase MtxX, methanogen marker protein 4</td>
</tr>
<tr>
<td>10</td>
<td>15</td>
<td><a href="/research/cog/cog/COG4007/">COG4007</a></td>
<td>
R
</td>
<td>Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase</td>
</tr>
<tr>
<td>61</td>
<td>61</td>
<td><a href="/research/cog/cog/COG4012/">COG4012</a></td>
<td>
R
</td>
<td>Uncharacterized protein, DUF1786 family, actin-like ATPase superfamily</td>
</tr>
<tr>
<td>14</td>
<td>14</td>
<td><a href="/research/cog/cog/COG4015/">COG4015</a></td>
<td>
R
</td>
<td>Predicted dinucleotide-utilizing enzyme of the ThiF/HesA family</td>
</tr>
<tr>
<td>34</td>
<td>34</td>
<td><a href="/research/cog/cog/COG4020/">COG4020</a></td>
<td>
R
</td>
<td>Predicted ATPase/kinase of ASKHA (acetate and sugar kinases, HSC70, actin) superfamily</td>
</tr>
<tr>
<td>9</td>
<td>9</td>
<td><a href="/research/cog/cog/COG4025/">COG4025</a></td>
<td>
R
</td>
<td>Predicted component of archaeal type IV pili-like system, DUF2101 family</td>
</tr>
<tr>
<td>16</td>
<td>16</td>
<td><a href="/research/cog/cog/COG4026/">COG4026</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease</td>
</tr>
<tr>
<td>63</td>
<td>64</td>
<td><a href="/research/cog/cog/COG4028/">COG4028</a></td>
<td>
R
</td>
<td>Predicted P-loop ATPase/GTPase</td>
</tr>
<tr>
<td>34</td>
<td>34</td>
<td><a href="/research/cog/cog/COG4030/">COG4030</a></td>
<td>
R
</td>
<td>Predicted phosphohydrolase, HAD superfamily</td>
</tr>
<tr>
<td>61</td>
<td>77</td>
<td><a href="/research/cog/cog/COG4043/">COG4043</a></td>
<td>
R
</td>
<td>ASC-1 homology (ASCH) domain, predicted RNA-binding domain</td>
</tr>
<tr>
<td>10</td>
<td>10</td>
<td><a href="/research/cog/cog/COG4049/">COG4049</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains archaeal-type C2H2 Zn-finger</td>
</tr>
<tr>
<td>44</td>
<td>48</td>
<td><a href="/research/cog/cog/COG4052/">COG4052</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein related to methyl-CoM reductase subunit C, methanogenesis marker protein 7</td>
</tr>
<tr>
<td>34</td>
<td>44</td>
<td><a href="/research/cog/cog/COG4068/">COG4068</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>46</td>
<td>48</td>
<td><a href="/research/cog/cog/COG4070/">COG4070</a></td>
<td>
R
</td>
<td>Cyclophilin family protein MJ1412, methanogenesis marker protein 3</td>
</tr>
<tr>
<td>24</td>
<td>24</td>
<td><a href="/research/cog/cog/COG4071/">COG4071</a></td>
<td>
R
</td>
<td>Gamma-glutamyl ligase family protein MJ1361</td>
</tr>
<tr>
<td>86</td>
<td>89</td>
<td><a href="/research/cog/cog/COG4076/">COG4076</a></td>
<td>
R
</td>
<td>Predicted RNA methylase</td>
</tr>
<tr>
<td>149</td>
<td>152</td>
<td><a href="/research/cog/cog/COG4087/">COG4087</a></td>
<td>
R
</td>
<td>Soluble P-type ATPase</td>
</tr>
<tr>
<td>371</td>
<td>659</td>
<td><a href="/research/cog/cog/COG4099/">COG4099</a></td>
<td>
R
</td>
<td>Predicted peptidase</td>
</tr>
<tr>
<td>378</td>
<td>386</td>
<td><a href="/research/cog/cog/COG4100/">COG4100</a></td>
<td>
P
R
</td>
<td>Cystathionine beta-lyase family protein involved in aluminum resistance</td>
</tr>
<tr>
<td>202</td>
<td>240</td>
<td><a href="/research/cog/cog/COG4101/">COG4101</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, RmlC-like cupin domain</td>
</tr>
<tr>
<td>99</td>
<td>99</td>
<td><a href="/research/cog/cog/COG4112/">COG4112</a></td>
<td>
R
</td>
<td>Predicted phosphoesterase YmaB, NUDIX family</td>
</tr>
<tr>
<td>130</td>
<td>131</td>
<td><a href="/research/cog/cog/COG4116/">COG4116</a></td>
<td>
R
</td>
<td>Predicted triphosphatase or cyclase YjbK, contains CYTH domain</td>
</tr>
<tr>
<td>169</td>
<td>179</td>
<td><a href="/research/cog/cog/COG4119/">COG4119</a></td>
<td>
F
R
</td>
<td>Predicted NTP pyrophosphohydrolase, NUDIX family</td>
</tr>
<tr>
<td>461</td>
<td>559</td>
<td><a href="/research/cog/cog/COG4120/">COG4120</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>178</td>
<td>190</td>
<td><a href="/research/cog/cog/COG4127/">COG4127</a></td>
<td>
R
</td>
<td>Predicted restriction endonuclease, Mrr-cat superfamily</td>
</tr>
<tr>
<td>56</td>
<td>70</td>
<td><a href="/research/cog/cog/COG4128/">COG4128</a></td>
<td>
R
</td>
<td>Zona occludens toxin, predicted ATPase</td>
</tr>
<tr>
<td>493</td>
<td>764</td>
<td><a href="/research/cog/cog/COG4129/">COG4129</a></td>
<td>
R
</td>
<td>Predicted membrane transporter YgaE, aromatic acid exporter family</td>
</tr>
<tr>
<td>187</td>
<td>195</td>
<td><a href="/research/cog/cog/COG4132/">COG4132</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>299</td>
<td>350</td>
<td><a href="/research/cog/cog/COG4134/">COG4134</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system YnjBCD, periplasmic component</td>
</tr>
<tr>
<td>135</td>
<td>136</td>
<td><a href="/research/cog/cog/COG4135/">COG4135</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system YnjBCD, permease component</td>
</tr>
<tr>
<td>131</td>
<td>131</td>
<td><a href="/research/cog/cog/COG4136/">COG4136</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system YnjBCD, ATPase component</td>
</tr>
<tr>
<td>593</td>
<td>593</td>
<td><a href="/research/cog/cog/COG4137/">COG4137</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>338</td>
<td>617</td>
<td><a href="/research/cog/cog/COG4146/">COG4146</a></td>
<td>
R
</td>
<td>Uncharacterized membrane permease YidK, sodium:solute symporter family</td>
</tr>
<tr>
<td>589</td>
<td>637</td>
<td><a href="/research/cog/cog/COG4152/">COG4152</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, ATPase component</td>
</tr>
<tr>
<td>101</td>
<td>109</td>
<td><a href="/research/cog/cog/COG4158/">COG4158</a></td>
<td>
R
</td>
<td>Predicted ABC-type sugar transport system, permease component</td>
</tr>
<tr>
<td>339</td>
<td>487</td>
<td><a href="/research/cog/cog/COG4178/">COG4178</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease and ATPase components</td>
</tr>
<tr>
<td>278</td>
<td>331</td>
<td><a href="/research/cog/cog/COG4185/">COG4185</a></td>
<td>
R
</td>
<td>Predicted ABC-type ATPase or kinase, zeta toxin family</td>
</tr>
<tr>
<td>165</td>
<td>190</td>
<td><a href="/research/cog/cog/COG4186/">COG4186</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein MJ1445, calcineurin-like phosphoesterase superfamily</td>
</tr>
<tr>
<td>502</td>
<td>875</td>
<td><a href="/research/cog/cog/COG4188/">COG4188</a></td>
<td>
R
</td>
<td>Predicted dienelactone hydrolase</td>
</tr>
<tr>
<td>289</td>
<td>373</td>
<td><a href="/research/cog/cog/COG4226/">COG4226</a></td>
<td>
R
</td>
<td>Predicted nuclease of the RNAse H fold, HicB family</td>
</tr>
<tr>
<td>161</td>
<td>164</td>
<td><a href="/research/cog/cog/COG4240/">COG4240</a></td>
<td>
R
</td>
<td>Pantothenate kinase-related protein Tda10 (topoisomerase I damage affected protein)</td>
</tr>
<tr>
<td>373</td>
<td>562</td>
<td><a href="/research/cog/cog/COG4242/">COG4242</a></td>
<td>
Q
R
</td>
<td>Cyanophycinase and related exopeptidases</td>
</tr>
<tr>
<td>386</td>
<td>440</td>
<td><a href="/research/cog/cog/COG4243/">COG4243</a></td>
<td>
R
</td>
<td>Vitamin K epoxide reductase (VKOR) family protein, predicted involvement in disulfide bond formation</td>
</tr>
<tr>
<td>172</td>
<td>221</td>
<td><a href="/research/cog/cog/COG4248/">COG4248</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YegI with protein kinase and helix-hairpin-helix DNA-binding domains</td>
</tr>
<tr>
<td>421</td>
<td>1096</td>
<td><a href="/research/cog/cog/COG4249/">COG4249</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains caspase domain</td>
</tr>
<tr>
<td>402</td>
<td>650</td>
<td><a href="/research/cog/cog/COG4254/">COG4254</a></td>
<td>
R
</td>
<td>Uncharacterized peptidoglycan binding protein, contains LysM and FecR domains</td>
</tr>
<tr>
<td>288</td>
<td>293</td>
<td><a href="/research/cog/cog/COG4258/">COG4258</a></td>
<td>
R
</td>
<td>Predicted exporter</td>
</tr>
<tr>
<td>285</td>
<td>293</td>
<td><a href="/research/cog/cog/COG4261/">COG4261</a></td>
<td>
R
</td>
<td>Predicted acyltransferase, LPLAT superfamily</td>
</tr>
<tr>
<td>360</td>
<td>419</td>
<td><a href="/research/cog/cog/COG4262/">COG4262</a></td>
<td>
R
</td>
<td>Predicted spermidine synthase with an N-terminal membrane domain</td>
</tr>
<tr>
<td>428</td>
<td>577</td>
<td><a href="/research/cog/cog/COG4270/">COG4270</a></td>
<td>
R
</td>
<td>Membrane protein DoxX, possibly involved in oxidative stress resistance</td>
</tr>
<tr>
<td>142</td>
<td>154</td>
<td><a href="/research/cog/cog/COG4271/">COG4271</a></td>
<td>
R
</td>
<td>Predicted nucleotide-binding protein containing TIR -like domain</td>
</tr>
<tr>
<td>506</td>
<td>613</td>
<td><a href="/research/cog/cog/COG4276/">COG4276</a></td>
<td>
R
</td>
<td>Ligand-binding SRPBCC domain</td>
</tr>
<tr>
<td>458</td>
<td>462</td>
<td><a href="/research/cog/cog/COG4277/">COG4277</a></td>
<td>
R
</td>
<td>Predicted DNA modification or repair protein, contains radical SAM and helix-hairpin-helix domains</td>
</tr>
<tr>
<td>174</td>
<td>190</td>
<td><a href="/research/cog/cog/COG4283/">COG4283</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein DfsB/IRC4, DUF1706 (PF08020) domain</td>
</tr>
<tr>
<td>78</td>
<td>99</td>
<td><a href="/research/cog/cog/COG4285/">COG4285</a></td>
<td>
R
</td>
<td>Uncharacterized protein, conains N-terminal GATase1-like BPL-N domain</td>
</tr>
<tr>
<td>91</td>
<td>98</td>
<td><a href="/research/cog/cog/COG4287/">COG4287</a></td>
<td>
R
</td>
<td>PhoPQ-activated pathogenicity-related protein</td>
</tr>
<tr>
<td>108</td>
<td>114</td>
<td><a href="/research/cog/cog/COG4295/">COG4295</a></td>
<td>
R
</td>
<td>Predicted RNA repair component, a phosphatase of H2Macro superfamily, DUF2263 family</td>
</tr>
<tr>
<td>289</td>
<td>517</td>
<td><a href="/research/cog/cog/COG4299/">COG4299</a></td>
<td>
R
</td>
<td>Predicted acyltransferase, DUF1624 domain</td>
</tr>
<tr>
<td>576</td>
<td>617</td>
<td><a href="/research/cog/cog/COG4301/">COG4301</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains predicted SAM-dependent methyltransferase domain</td>
</tr>
<tr>
<td>257</td>
<td>339</td>
<td><a href="/research/cog/cog/COG4309/">COG4309</a></td>
<td>
R
</td>
<td>SirA-like two-layered alpha/beta sandwich domain, DUF2249 family</td>
</tr>
<tr>
<td>90</td>
<td>93</td>
<td><a href="/research/cog/cog/COG4310/">COG4310</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, cotains an aminopeptidase-like domain</td>
</tr>
<tr>
<td>233</td>
<td>373</td>
<td><a href="/research/cog/cog/COG4312/">COG4312</a></td>
<td>
R
</td>
<td>Predicted dithiol-disulfide oxidoreductase, DUF899 family</td>
</tr>
<tr>
<td>336</td>
<td>480</td>
<td><a href="/research/cog/cog/COG4321/">COG4321</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein, contains ribbon-helix-helix (RHH) domain</td>
</tr>
<tr>
<td>143</td>
<td>144</td>
<td><a href="/research/cog/cog/COG4324/">COG4324</a></td>
<td>
R
</td>
<td>Predicted aminopeptidase</td>
</tr>
<tr>
<td>109</td>
<td>112</td>
<td><a href="/research/cog/cog/COG4328/">COG4328</a></td>
<td>
R
</td>
<td>Predicted nuclease (RNAse H fold)</td>
</tr>
<tr>
<td>359</td>
<td>432</td>
<td><a href="/research/cog/cog/COG4339/">COG4339</a></td>
<td>
R
</td>
<td>Predicted metal-dependent phosphohydrolase, HD superfamily</td>
</tr>
<tr>
<td>202</td>
<td>218</td>
<td><a href="/research/cog/cog/COG4340/">COG4340</a></td>
<td>
R
</td>
<td>Predicted dioxygenase, 2-oxoglutarate and Fe-dependent (2OG-Fe) dioxygenase superfamily</td>
</tr>
<tr>
<td>217</td>
<td>264</td>
<td><a href="/research/cog/cog/COG4341/">COG4341</a></td>
<td>
R
</td>
<td>Predicted HD phosphohydrolase</td>
</tr>
<tr>
<td>29</td>
<td>30</td>
<td><a href="/research/cog/cog/COG4345/">COG4345</a></td>
<td>
R
</td>
<td>Predicted DNA binding protein, Pae2254/DUF2258 family</td>
</tr>
<tr>
<td>21</td>
<td>21</td>
<td><a href="/research/cog/cog/COG4353/">COG4353</a></td>
<td>
R
</td>
<td>Acetyltransferase superfamily protein, DUF1122 family</td>
</tr>
<tr>
<td>75</td>
<td>80</td>
<td><a href="/research/cog/cog/COG4377/">COG4377</a></td>
<td>
R
</td>
<td>Predicted metal-dependent membrane protease YhfC, DUF2324 family</td>
</tr>
<tr>
<td>307</td>
<td>347</td>
<td><a href="/research/cog/cog/COG4405/">COG4405</a></td>
<td>
R
</td>
<td>Predicted RNA-binding protein YhfF, contains PUA-like ASCH domain</td>
</tr>
<tr>
<td>56</td>
<td>79</td>
<td><a href="/research/cog/cog/COG4449/">COG4449</a></td>
<td>
R
</td>
<td>Predicted protease, Abi (CAAX) family</td>
</tr>
<tr>
<td>290</td>
<td>396</td>
<td><a href="/research/cog/cog/COG4454/">COG4454</a></td>
<td>
R
</td>
<td>Uncharacterized copper-binding protein, cupredoxin-like subfamily</td>
</tr>
<tr>
<td>224</td>
<td>233</td>
<td><a href="/research/cog/cog/COG4469/">COG4469</a></td>
<td>
R
</td>
<td>Competence protein CoiA, contains predicted nuclease domain</td>
</tr>
<tr>
<td>232</td>
<td>234</td>
<td><a href="/research/cog/cog/COG4492/">COG4492</a></td>
<td>
R
</td>
<td>ACT domain-containing protein, UPF0735 family</td>
</tr>
<tr>
<td>364</td>
<td>382</td>
<td><a href="/research/cog/cog/COG4496/">COG4496</a></td>
<td>
R
</td>
<td>Predicted DNA-binding transcriptional regulator YerC, contains ArsR-like HTH domain</td>
</tr>
<tr>
<td>396</td>
<td>547</td>
<td><a href="/research/cog/cog/COG4529/">COG4529</a></td>
<td>
R
</td>
<td>Uncharacterized NAD(P)/FAD-binding protein YdhS</td>
</tr>
<tr>
<td>136</td>
<td>141</td>
<td><a href="/research/cog/cog/COG4551/">COG4551</a></td>
<td>
R
</td>
<td>Predicted protein tyrosine phosphatase</td>
</tr>
<tr>
<td>514</td>
<td>708</td>
<td><a href="/research/cog/cog/COG4552/">COG4552</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase</td>
</tr>
<tr>
<td>343</td>
<td>441</td>
<td><a href="/research/cog/cog/COG4586/">COG4586</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, ATPase component</td>
</tr>
<tr>
<td>340</td>
<td>444</td>
<td><a href="/research/cog/cog/COG4587/">COG4587</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>389</td>
<td>428</td>
<td><a href="/research/cog/cog/COG4589/">COG4589</a></td>
<td>
R
</td>
<td>Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase</td>
</tr>
<tr>
<td>168</td>
<td>169</td>
<td><a href="/research/cog/cog/COG4590/">COG4590</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, permease component</td>
</tr>
<tr>
<td>248</td>
<td>310</td>
<td><a href="/research/cog/cog/COG4627/">COG4627</a></td>
<td>
R
</td>
<td>Predicted SAM-depedendent methyltransferase</td>
</tr>
<tr>
<td>195</td>
<td>243</td>
<td><a href="/research/cog/cog/COG4633/">COG4633</a></td>
<td>
R
</td>
<td>Cupredoxin-like domain</td>
</tr>
<tr>
<td>216</td>
<td>456</td>
<td><a href="/research/cog/cog/COG4634/">COG4634</a></td>
<td>
R
</td>
<td>Predicted nuclease, contains PIN domain, potential toxin-antitoxin system component</td>
</tr>
<tr>
<td>437</td>
<td>5363</td>
<td><a href="/research/cog/cog/COG4636/">COG4636</a></td>
<td>
R
</td>
<td>Endonuclease, Uma2 family (restriction endonuclease fold)</td>
</tr>
<tr>
<td>511</td>
<td>896</td>
<td><a href="/research/cog/cog/COG4637/">COG4637</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>619</td>
<td>1565</td>
<td><a href="/research/cog/cog/COG4638/">COG4638</a></td>
<td>
P
R
</td>
<td>Phenylpropionate dioxygenase or related ring-hydroxylating dioxygenase, large terminal subunit</td>
</tr>
<tr>
<td>338</td>
<td>488</td>
<td><a href="/research/cog/cog/COG4639/">COG4639</a></td>
<td>
R
</td>
<td>Predicted kinase</td>
</tr>
<tr>
<td>288</td>
<td>391</td>
<td><a href="/research/cog/cog/COG4642/">COG4642</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains MORN repeats</td>
</tr>
<tr>
<td>225</td>
<td>275</td>
<td><a href="/research/cog/cog/COG4645/">COG4645</a></td>
<td>
R
</td>
<td>Predicted acyltransferase, DUF1624 domain</td>
</tr>
<tr>
<td>102</td>
<td>113</td>
<td><a href="/research/cog/cog/COG4655/">COG4655</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains TadX/Tad_C domain</td>
</tr>
<tr>
<td>556</td>
<td>1220</td>
<td><a href="/research/cog/cog/COG4666/">COG4666</a></td>
<td>
R
</td>
<td>TRAP-type uncharacterized transport system, fused permease components</td>
</tr>
<tr>
<td>477</td>
<td>595</td>
<td><a href="/research/cog/cog/COG4674/">COG4674</a></td>
<td>
R
</td>
<td>ABC-type uncharacterized transport system, ATPase component</td>
</tr>
<tr>
<td>377</td>
<td>384</td>
<td><a href="/research/cog/cog/COG4681/">COG4681</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YaeQ, putative virulence regulator</td>
</tr>
<tr>
<td>154</td>
<td>180</td>
<td><a href="/research/cog/cog/COG4710/">COG4710</a></td>
<td>
R
</td>
<td>Predicted DNA-binding protein with an HTH domain</td>
</tr>
<tr>
<td>11</td>
<td>12</td>
<td><a href="/research/cog/cog/COG4740/">COG4740</a></td>
<td>
R
</td>
<td>Predicted metalloprotease</td>
</tr>
<tr>
<td>107</td>
<td>157</td>
<td><a href="/research/cog/cog/COG4745/">COG4745</a></td>
<td>
R
</td>
<td>Predicted membrane-bound mannosyltransferase, involved in protein glycosylation</td>
</tr>
<tr>
<td>373</td>
<td>475</td>
<td><a href="/research/cog/cog/COG4747/">COG4747</a></td>
<td>
R
</td>
<td>ACT domain-containing protein</td>
</tr>
<tr>
<td>208</td>
<td>213</td>
<td><a href="/research/cog/cog/COG4754/">COG4754</a></td>
<td>
R
</td>
<td>Extracellular substrate-binding protein</td>
</tr>
<tr>
<td>32</td>
<td>46</td>
<td><a href="/research/cog/cog/COG4756/">COG4756</a></td>
<td>
R
</td>
<td>Predicted cation transporter, DUF1646 domain</td>
</tr>
<tr>
<td>257</td>
<td>300</td>
<td><a href="/research/cog/cog/COG4757/">COG4757</a></td>
<td>
R
</td>
<td>Predicted alpha/beta hydrolase</td>
</tr>
<tr>
<td>139</td>
<td>185</td>
<td><a href="/research/cog/cog/COG4759/">COG4759</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains thioredoxin-like domain</td>
</tr>
<tr>
<td>334</td>
<td>345</td>
<td><a href="/research/cog/cog/COG4760/">COG4760</a></td>
<td>
R
</td>
<td>Bax inhibitor-1-like(BI-1-like)/BC_2152 family protein, possible role in calcium leak</td>
</tr>
<tr>
<td>276</td>
<td>282</td>
<td><a href="/research/cog/cog/COG4764/">COG4764</a></td>
<td>
R
</td>
<td>Predicted transglycosylase, contains SLT domain</td>
</tr>
<tr>
<td>271</td>
<td>404</td>
<td><a href="/research/cog/cog/COG4782/">COG4782</a></td>
<td>
R
</td>
<td>Esterase/lipase superfamily enzyme</td>
</tr>
<tr>
<td>265</td>
<td>285</td>
<td><a href="/research/cog/cog/COG4784/">COG4784</a></td>
<td>
R
</td>
<td>Putative Zn-dependent protease</td>
</tr>
<tr>
<td>55</td>
<td>67</td>
<td><a href="/research/cog/cog/COG4797/">COG4797</a></td>
<td>
R
</td>
<td>Predicted regulatory domain of a methyltransferase</td>
</tr>
<tr>
<td>238</td>
<td>359</td>
<td><a href="/research/cog/cog/COG4798/">COG4798</a></td>
<td>
R
</td>
<td>Predicted methyltransferase</td>
</tr>
<tr>
<td>82</td>
<td>87</td>
<td><a href="/research/cog/cog/COG4801/">COG4801</a></td>
<td>
R
</td>
<td>Predicted acyltransferase, contains DUF342 domain</td>
</tr>
<tr>
<td>334</td>
<td>579</td>
<td><a href="/research/cog/cog/COG4804/">COG4804</a></td>
<td>
R
</td>
<td>Predicted nuclease of restriction endonuclease-like (RecB) superfamily, DUF1016 family</td>
</tr>
<tr>
<td>235</td>
<td>313</td>
<td><a href="/research/cog/cog/COG4821/">COG4821</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains SIS (Sugar ISomerase) phosphosugar binding domain</td>
</tr>
<tr>
<td>210</td>
<td>212</td>
<td><a href="/research/cog/cog/COG4825/">COG4825</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains thiamine pyrophosphokinase N- and C- domains</td>
</tr>
<tr>
<td>28</td>
<td>32</td>
<td><a href="/research/cog/cog/COG4827/">COG4827</a></td>
<td>
R
</td>
<td>Predicted transporter</td>
</tr>
<tr>
<td>145</td>
<td>151</td>
<td><a href="/research/cog/cog/COG4848/">COG4848</a></td>
<td>
R
</td>
<td>YtpQ protein involved in methylglyoxal resistance, DUF1444/UPF0354 family</td>
</tr>
<tr>
<td>64</td>
<td>68</td>
<td><a href="/research/cog/cog/COG4849/">COG4849</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase</td>
</tr>
<tr>
<td>136</td>
<td>141</td>
<td><a href="/research/cog/cog/COG4851/">COG4851</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein involved in sex pheromone biosynthesis</td>
</tr>
<tr>
<td>248</td>
<td>264</td>
<td><a href="/research/cog/cog/COG4866/">COG4866</a></td>
<td>
R
</td>
<td>N-Acyltransferase, similar to phosphatidylglycerol lysyltransferase</td>
</tr>
<tr>
<td>225</td>
<td>229</td>
<td><a href="/research/cog/cog/COG4874/">COG4874</a></td>
<td>
R
</td>
<td>Amidinotransferase superfamily enzyme, FN0238 family</td>
</tr>
<tr>
<td>207</td>
<td>233</td>
<td><a href="/research/cog/cog/COG4880/">COG4880</a></td>
<td>
R
</td>
<td>Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats</td>
</tr>
<tr>
<td>21</td>
<td>26</td>
<td><a href="/research/cog/cog/COG4882/">COG4882</a></td>
<td>
R
</td>
<td>Predicted aminopeptidase, Iap family</td>
</tr>
<tr>
<td>36</td>
<td>37</td>
<td><a href="/research/cog/cog/COG4884/">COG4884</a></td>
<td>
R
</td>
<td>Conserved protein YfeS involved in borate resistance, contains WGR domain</td>
</tr>
<tr>
<td>240</td>
<td>356</td>
<td><a href="/research/cog/cog/COG4889/">COG4889</a></td>
<td>
R
</td>
<td>Predicted helicase</td>
</tr>
<tr>
<td>133</td>
<td>145</td>
<td><a href="/research/cog/cog/COG4892/">COG4892</a></td>
<td>
R
</td>
<td>Predicted heme/steroid binding protein</td>
</tr>
<tr>
<td>37</td>
<td>37</td>
<td><a href="/research/cog/cog/COG4900/">COG4900</a></td>
<td>
R
</td>
<td>Predicted metallopeptidase</td>
</tr>
<tr>
<td>130</td>
<td>150</td>
<td><a href="/research/cog/cog/COG4902/">COG4902</a></td>
<td>
R
</td>
<td>Ferritin-like protein MJ0754, DUF2202 family</td>
</tr>
<tr>
<td>373</td>
<td>721</td>
<td><a href="/research/cog/cog/COG4908/">COG4908</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, contains a NRPS condensation (elongation) domain</td>
</tr>
<tr>
<td>31</td>
<td>31</td>
<td><a href="/research/cog/cog/COG4914/">COG4914</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase</td>
</tr>
<tr>
<td>131</td>
<td>141</td>
<td><a href="/research/cog/cog/COG4915/">COG4915</a></td>
<td>
Q
R
</td>
<td>5-bromo-4-chloroindolyl phosphatase XpaC</td>
</tr>
<tr>
<td>71</td>
<td>75</td>
<td><a href="/research/cog/cog/COG4918/">COG4918</a></td>
<td>
R
</td>
<td>Predicted Fe-S cluster biosynthesis protein YqkB</td>
</tr>
<tr>
<td>273</td>
<td>361</td>
<td><a href="/research/cog/cog/COG4922/">COG4922</a></td>
<td>
R
</td>
<td>Predicted SnoaL-like aldol condensation-catalyzing enzyme</td>
</tr>
<tr>
<td>130</td>
<td>141</td>
<td><a href="/research/cog/cog/COG4923/">COG4923</a></td>
<td>
R
</td>
<td>Predicted nuclease (RNAse H fold)</td>
</tr>
<tr>
<td>182</td>
<td>206</td>
<td><a href="/research/cog/cog/COG4925/">COG4925</a></td>
<td>
R
</td>
<td>Cyclophilin-like family protein</td>
</tr>
<tr>
<td>245</td>
<td>301</td>
<td><a href="/research/cog/cog/COG4927/">COG4927</a></td>
<td>
R
</td>
<td>Isopenicillin-N-acyltransferase-related hydrolase or acyltransferase, C45 autoprotease family, Ntn-hydrolase superfamily</td>
</tr>
<tr>
<td>278</td>
<td>310</td>
<td><a href="/research/cog/cog/COG4928/">COG4928</a></td>
<td>
R
</td>
<td>Predicted P-loop ATPase, KAP-like</td>
</tr>
<tr>
<td>218</td>
<td>297</td>
<td><a href="/research/cog/cog/COG4938/">COG4938</a></td>
<td>
R
</td>
<td>Predicted ATPase</td>
</tr>
<tr>
<td>174</td>
<td>193</td>
<td><a href="/research/cog/cog/COG4947/">COG4947</a></td>
<td>
R
</td>
<td>Esterase/lipase superfamily enzyme</td>
</tr>
<tr>
<td>1481</td>
<td>5489</td>
<td><a href="/research/cog/cog/COG4948/">COG4948</a></td>
<td>
M
R
</td>
<td>L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily</td>
</tr>
<tr>
<td>504</td>
<td>506</td>
<td><a href="/research/cog/cog/COG4956/">COG4956</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YacL, contains PIN and TRAM domains</td>
</tr>
<tr>
<td>552</td>
<td>736</td>
<td><a href="/research/cog/cog/COG4976/">COG4976</a></td>
<td>
R
</td>
<td>Predicted methyltransferase, contains TPR repeat</td>
</tr>
<tr>
<td>392</td>
<td>532</td>
<td><a href="/research/cog/cog/COG4980/">COG4980</a></td>
<td>
R
</td>
<td>Gas vesicle protein YhaH</td>
</tr>
<tr>
<td>509</td>
<td>529</td>
<td><a href="/research/cog/cog/COG4989/">COG4989</a></td>
<td>
R
</td>
<td>Predicted oxidoreductase YdhF</td>
</tr>
<tr>
<td>149</td>
<td>255</td>
<td><a href="/research/cog/cog/COG4990/">COG4990</a></td>
<td>
R
</td>
<td>Predicted cysteine peptidase, C39 family</td>
</tr>
<tr>
<td>25</td>
<td>28</td>
<td><a href="/research/cog/cog/COG4996/">COG4996</a></td>
<td>
R
</td>
<td>Predicted phosphatase</td>
</tr>
<tr>
<td>169</td>
<td>178</td>
<td><a href="/research/cog/cog/COG4997/">COG4997</a></td>
<td>
R
</td>
<td>Predicted house-cleaning noncanonical NTP pyrophosphatase, all-alpha NTP-PPase (MazG) superfamily</td>
</tr>
<tr>
<td>29</td>
<td>35</td>
<td><a href="/research/cog/cog/COG5014/">COG5014</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein TM0948, MoaA-related, radical SAM superfamily</td>
</tr>
<tr>
<td>180</td>
<td>237</td>
<td><a href="/research/cog/cog/COG5015/">COG5015</a></td>
<td>
R
</td>
<td>Pyridoxamine 5&#x27;-phosphate oxidase (PNPOx-like) family protein</td>
</tr>
<tr>
<td>2</td>
<td>61</td>
<td><a href="/research/cog/cog/COG5048/">COG5048</a></td>
<td>
R
</td>
<td>Zn-finger-containing protein</td>
</tr>
<tr>
<td>18</td>
<td>18</td>
<td><a href="/research/cog/cog/COG5207/">COG5207</a></td>
<td>
R
</td>
<td>Uncharacterized Zn-finger protein, UBP-type</td>
</tr>
<tr>
<td>78</td>
<td>78</td>
<td><a href="/research/cog/cog/COG5258/">COG5258</a></td>
<td>
R
</td>
<td>GTPase</td>
</tr>
<tr>
<td>406</td>
<td>583</td>
<td><a href="/research/cog/cog/COG5266/">COG5266</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains GH25 family domain</td>
</tr>
<tr>
<td>16</td>
<td>17</td>
<td><a href="/research/cog/cog/COG5275/">COG5275</a></td>
<td>
R
</td>
<td>BRCT domain type II</td>
</tr>
<tr>
<td>69</td>
<td>76</td>
<td><a href="/research/cog/cog/COG5298/">COG5298</a></td>
<td>
R
</td>
<td>Predicted metal-dependent carbohydrate esterase YdaL, contains NodB-like catalytic (CE4) domain</td>
</tr>
<tr>
<td>283</td>
<td>545</td>
<td><a href="/research/cog/cog/COG5305/">COG5305</a></td>
<td>
R
</td>
<td>Uncharacterized membrane protein PF0508, contains N-terminal glycosyltransferase domain of PMT family</td>
</tr>
<tr>
<td>91</td>
<td>111</td>
<td><a href="/research/cog/cog/COG5306/">COG5306</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein MJ1470, contains DUF2341 domain, predicted component of type IV pili-like system</td>
</tr>
<tr>
<td>2</td>
<td>2</td>
<td><a href="/research/cog/cog/COG5307/">COG5307</a></td>
<td>
R
</td>
<td>Guanine-nucleotide exchange factor YEL1, contains Sec7 domain</td>
</tr>
<tr>
<td>199</td>
<td>208</td>
<td><a href="/research/cog/cog/COG5322/">COG5322</a></td>
<td>
R
</td>
<td>Predicted acyl-ACP reductase</td>
</tr>
<tr>
<td>234</td>
<td>450</td>
<td><a href="/research/cog/cog/COG5342/">COG5342</a></td>
<td>
R
</td>
<td>Invasion protein IalB, involved in pathogenesis</td>
</tr>
<tr>
<td>122</td>
<td>147</td>
<td><a href="/research/cog/cog/COG5350/">COG5350</a></td>
<td>
R
</td>
<td>Predicted protein tyrosine phosphatase</td>
</tr>
<tr>
<td>369</td>
<td>394</td>
<td><a href="/research/cog/cog/COG5360/">COG5360</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein, heparinase superfamily</td>
</tr>
<tr>
<td>59</td>
<td>78</td>
<td><a href="/research/cog/cog/COG5378/">COG5378</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains PIN domain</td>
</tr>
<tr>
<td>95</td>
<td>113</td>
<td><a href="/research/cog/cog/COG5397/">COG5397</a></td>
<td>
R
</td>
<td>Predicted nucleotidyltransferase superfamily protein</td>
</tr>
<tr>
<td>338</td>
<td>510</td>
<td><a href="/research/cog/cog/COG5426/">COG5426</a></td>
<td>
R
</td>
<td>Uncharacterized protein STM3548, contains class I glutamine amidotransferase domain</td>
</tr>
<tr>
<td>111</td>
<td>111</td>
<td><a href="/research/cog/cog/COG5431/">COG5431</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains SWIM-type Zn-finger domain</td>
</tr>
<tr>
<td>49</td>
<td>70</td>
<td><a href="/research/cog/cog/COG5439/">COG5439</a></td>
<td>
R
</td>
<td>STAS domain</td>
</tr>
<tr>
<td>322</td>
<td>337</td>
<td><a href="/research/cog/cog/COG5465/">COG5465</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YbjN, helps stabilize unstable proteins</td>
</tr>
<tr>
<td>309</td>
<td>523</td>
<td><a href="/research/cog/cog/COG5476/">COG5476</a></td>
<td>
R
</td>
<td>Microcystin degradation protein MlrC, contains DUF1485 domain</td>
</tr>
<tr>
<td>295</td>
<td>719</td>
<td><a href="/research/cog/cog/COG5492/">COG5492</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YjdB, contains Ig-like domain</td>
</tr>
<tr>
<td>46</td>
<td>111</td>
<td><a href="/research/cog/cog/COG5493/">COG5493</a></td>
<td>
R
</td>
<td>Uncharacterized protein, contains PD-(D/E)XK nuclease domain</td>
</tr>
<tr>
<td>592</td>
<td>595</td>
<td><a href="/research/cog/cog/COG5495/">COG5495</a></td>
<td>
R
</td>
<td>Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains</td>
</tr>
<tr>
<td>350</td>
<td>378</td>
<td><a href="/research/cog/cog/COG5496/">COG5496</a></td>
<td>
R
</td>
<td>Fluoroacetyl-CoA thioesterase (FlK)-like esterase</td>
</tr>
<tr>
<td>133</td>
<td>170</td>
<td><a href="/research/cog/cog/COG5504/">COG5504</a></td>
<td>
R
</td>
<td>Predicted Zn-dependent protease YjaZ, DUF2268 family</td>
</tr>
<tr>
<td>327</td>
<td>327</td>
<td><a href="/research/cog/cog/COG5512/">COG5512</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-ribbon domain (includes truncated derivatives)</td>
</tr>
<tr>
<td>302</td>
<td>656</td>
<td><a href="/research/cog/cog/COG5516/">COG5516</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding</td>
</tr>
<tr>
<td>159</td>
<td>212</td>
<td><a href="/research/cog/cog/COG5519/">COG5519</a></td>
<td>
R
</td>
<td>Predicted ATPase domain of Cch-like helicases, DUF927 family</td>
</tr>
<tr>
<td>22</td>
<td>26</td>
<td><a href="/research/cog/cog/COG5526/">COG5526</a></td>
<td>
R
</td>
<td>Lysozyme family protein</td>
</tr>
<tr>
<td>54</td>
<td>58</td>
<td><a href="/research/cog/cog/COG5532/">COG5532</a></td>
<td>
R
</td>
<td>Conserved protein YfdQ, affects toxicity of methyl methanesulfonate, YfdQ/DUF2303 family</td>
</tr>
<tr>
<td>209</td>
<td>266</td>
<td><a href="/research/cog/cog/COG5553/">COG5553</a></td>
<td>
R
</td>
<td>Predicted metal-dependent enzyme of the double-stranded beta helix superfamily</td>
</tr>
<tr>
<td>198</td>
<td>255</td>
<td><a href="/research/cog/cog/COG5573/">COG5573</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains PIN domain</td>
</tr>
<tr>
<td>55</td>
<td>66</td>
<td><a href="/research/cog/cog/COG5592/">COG5592</a></td>
<td>
R
</td>
<td>Hemerythrin domain-containing protein</td>
</tr>
<tr>
<td>52</td>
<td>52</td>
<td><a href="/research/cog/cog/COG5595/">COG5595</a></td>
<td>
R
</td>
<td>Predicted nucleic acid-binding protein, contains Zn-ribbon domain</td>
</tr>
<tr>
<td>132</td>
<td>160</td>
<td><a href="/research/cog/cog/COG5610/">COG5610</a></td>
<td>
R
</td>
<td>Predicted sugar hydrolase, contains GT1 and HAD domains</td>
</tr>
<tr>
<td>204</td>
<td>262</td>
<td><a href="/research/cog/cog/COG5611/">COG5611</a></td>
<td>
R
</td>
<td>Predicted nucleic-acid-binding protein, contains PIN domain</td>
</tr>
<tr>
<td>106</td>
<td>138</td>
<td><a href="/research/cog/cog/COG5617/">COG5617</a></td>
<td>
R
</td>
<td>Predicted membrane glycosyltransferase TK1552, contains 6-pyruvoyl-tetrahydropterin synthase (PTPS)-related domain</td>
</tr>
<tr>
<td>291</td>
<td>307</td>
<td><a href="/research/cog/cog/COG5621/">COG5621</a></td>
<td>
R
</td>
<td>Predicted lipocalin, contains AttH/CrtC domain</td>
</tr>
<tr>
<td>106</td>
<td>120</td>
<td><a href="/research/cog/cog/COG5628/">COG5628</a></td>
<td>
R
</td>
<td>Predicted acetyltransferase</td>
</tr>
<tr>
<td>16</td>
<td>25</td>
<td><a href="/research/cog/cog/COG5643/">COG5643</a></td>
<td>
R
</td>
<td>Polyferredoxin, FmdE/FwdE family</td>
</tr>
<tr>
<td>134</td>
<td>155</td>
<td><a href="/research/cog/cog/COG5663/">COG5663</a></td>
<td>
R
</td>
<td>Uncharacterized conserved protein YqfW, HAD superfamily</td>
</tr>
<tr>
<td>67</td>
<td>72</td>
<td><a href="/research/cog/cog/COG5877/">COG5877</a></td>
<td>
R
</td>
<td>Predicted amidase domain</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</section>
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