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M - NCBI
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Updated: February, 2025
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<span class="headername">Database of Clusters of Orthologous Genes (COGs)</span>
<ul data-jig="ncbimenu" id="ui-ncbimenu-1" role="menubar">
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<a href="/research/cog/cogcategory/J/" title="COG Categories"
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J - Translation, ribosomal structure and biogenesis</a>
<a href="/research/cog/cogcategory/A/" title="COG Categories"
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A - RNA processing and modification</a>
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K - Transcription</a>
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L - Replication, recombination and repair</a>
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B - Chromatin structure and dynamics</a>
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D - Cell cycle control, cell division, chromosome partitioning</a>
<a href="/research/cog/cogcategory/Y/" title="COG Categories"
class="uppercase"
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Y - Nuclear structure</a>
<a href="/research/cog/cogcategory/V/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
V - Defense mechanisms</a>
<a href="/research/cog/cogcategory/T/" title="COG Categories"
class="uppercase"
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T - Signal transduction mechanisms</a>
<a href="/research/cog/cogcategory/M/" title="COG Categories"
class="uppercase"
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M - Cell wall/membrane/envelope biogenesis</a>
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N - Cell motility</a>
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Z - Cytoskeleton</a>
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W - Extracellular structures</a>
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U - Intracellular trafficking, secretion, and vesicular transport</a>
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O - Posttranslational modification, protein turnover, chaperones</a>
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X - nan</a>
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C - Energy production and conversion</a>
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class="uppercase"
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style="font-weight: normal;"
id="ui-ncbimenu-1_2">
G - Carbohydrate transport and metabolism</a>
<a href="/research/cog/cogcategory/E/" title="COG Categories"
class="uppercase"
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E - Amino acid transport and metabolism</a>
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class="uppercase"
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style="font-weight: normal;"
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F - Nucleotide transport and metabolism</a>
<a href="/research/cog/cogcategory/H/" title="COG Categories"
class="uppercase"
role="menuitem"
style="font-weight: normal;"
id="ui-ncbimenu-1_2">
H - Coenzyme transport and metabolism</a>
<a href="/research/cog/cogcategory/I/" title="COG Categories"
class="uppercase"
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style="font-weight: normal;"
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I - Lipid transport and metabolism</a>
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class="uppercase"
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P - Inorganic ion transport and metabolism</a>
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Q - Secondary metabolites biosynthesis, transport and catabolism</a>
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R - General function prediction only</a>
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class="uppercase"
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S - Function unknown</a>
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<section class="usa-section cog_top_section">
<div class="usa-grid">
<h1>M<span style='font-weight: 100'> - Cell wall/membrane/envelope biogenesis</span></h1>
<div style="float: right; clear: both;margin-top: -53px;">
<a class="usa-button" href="#" onclick="download_table_as_tsv('cog_result_table');">Download</a>
</div>
<h2>Stats</h2>
<div style="width: 60%">
<div class="ui-ncbigrid-outer-div organism_cog_table">
<div class="ui-ncbigrid-inner-div">
<table data-jig="ncbigrid">
<thead>
<tr>
<th>COG<br>definitions</th>
<th>Organims</th>
<th>Proteins</th>
<th>Median Protein<br>Length</th>
<th>Genes</th>
</tr>
</thead>
<tbody>
<tr>
<td>261</td>
<td>2,295</td>
<td>453,192</td>
<td>362.0</td>
<td>252</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="ui-ncbigrid-outer-div" style="font-size: 80%;">
<div class="ui-ncbigrid-inner-div">
<table id="cog_result_table" data-jig="ncbigrid">
<thead>
<tr>
<th>Organism</th>
<th>Protein</th>
<th>COG</th>
<th>Cat</th>
<th>Annotation</th>
</tr>
</thead>
<tbody>
<tr>
<td>301</td>
<td>352</td>
<td><a href="/research/cog/cog/COG0170/">COG0170</a></td>
<td>
M
O
</td>
<td>Dolichol kinase</td>
</tr>
<tr>
<td>2114</td>
<td>5103</td>
<td><a href="/research/cog/cog/COG0329/">COG0329</a></td>
<td>
M
E
</td>
<td>4-hydroxy-tetrahydrodipicolinate synthase/N-acetylneuraminate lyase</td>
</tr>
<tr>
<td>1352</td>
<td>1964</td>
<td><a href="/research/cog/cog/COG0381/">COG0381</a></td>
<td>
M
</td>
<td>UDP-N-acetylglucosamine 2-epimerase</td>
</tr>
<tr>
<td>901</td>
<td>1299</td>
<td><a href="/research/cog/cog/COG0392/">COG0392</a></td>
<td>
M
</td>
<td>Predicted membrane flippase AglD2/YbhN, UPF0104 family</td>
</tr>
<tr>
<td>1799</td>
<td>4857</td>
<td><a href="/research/cog/cog/COG0399/">COG0399</a></td>
<td>
M
</td>
<td>dTDP-4-amino-4,6-dideoxygalactose transaminase</td>
</tr>
<tr>
<td>303</td>
<td>347</td>
<td><a href="/research/cog/cog/COG0434/">COG0434</a></td>
<td>
M
</td>
<td>Membrane biogenesis protein, BtpA/SgcQ family</td>
</tr>
<tr>
<td>2199</td>
<td>29347</td>
<td><a href="/research/cog/cog/COG0438/">COG0438</a></td>
<td>
M
</td>
<td>Lipopolysaccharide 1,6-galactosyltransferase, GT1 family</td>
</tr>
<tr>
<td>2139</td>
<td>2643</td>
<td><a href="/research/cog/cog/COG0449/">COG0449</a></td>
<td>
M
</td>
<td>Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains</td>
</tr>
<tr>
<td>2134</td>
<td>16200</td>
<td><a href="/research/cog/cog/COG0451/">COG0451</a></td>
<td>
M
</td>
<td>Nucleoside-diphosphate-sugar epimerase</td>
</tr>
<tr>
<td>2198</td>
<td>17824</td>
<td><a href="/research/cog/cog/COG0463/">COG0463</a></td>
<td>
M
</td>
<td>Glycosyltransferase involved in cell wall bisynthesis</td>
</tr>
<tr>
<td>1254</td>
<td>2738</td>
<td><a href="/research/cog/cog/COG0464/">COG0464</a></td>
<td>
D
T
M
</td>
<td>AAA+-type ATPase, SpoVK/Ycf46/Vps4 family</td>
</tr>
<tr>
<td>2133</td>
<td>3820</td>
<td><a href="/research/cog/cog/COG0472/">COG0472</a></td>
<td>
M
</td>
<td>UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase/archaeal AglH</td>
</tr>
<tr>
<td>473</td>
<td>512</td>
<td><a href="/research/cog/cog/COG0562/">COG0562</a></td>
<td>
M
</td>
<td>UDP-galactopyranose mutase</td>
</tr>
<tr>
<td>1603</td>
<td>3496</td>
<td><a href="/research/cog/cog/COG0586/">COG0586</a></td>
<td>
M
</td>
<td>Undecaprenyl phosphate translocase (flippase), DedA/Tvp38 family</td>
</tr>
<tr>
<td>2030</td>
<td>2344</td>
<td><a href="/research/cog/cog/COG0597/">COG0597</a></td>
<td>
M
U
</td>
<td>Lipoprotein signal peptidase</td>
</tr>
<tr>
<td>490</td>
<td>537</td>
<td><a href="/research/cog/cog/COG0615/">COG0615</a></td>
<td>
M
</td>
<td>Glycerol-3-phosphate cytidylyltransferase, cytidylyltransferase family</td>
</tr>
<tr>
<td>1935</td>
<td>4296</td>
<td><a href="/research/cog/cog/COG0668/">COG0668</a></td>
<td>
M
</td>
<td>Small-conductance mechanosensitive channel</td>
</tr>
<tr>
<td>1321</td>
<td>1782</td>
<td><a href="/research/cog/cog/COG0677/">COG0677</a></td>
<td>
M
</td>
<td>UDP-N-acetyl-D-mannosaminuronate dehydrogenase</td>
</tr>
<tr>
<td>2027</td>
<td>2450</td>
<td><a href="/research/cog/cog/COG0682/">COG0682</a></td>
<td>
M
</td>
<td>Prolipoprotein diacylglyceryltransferase</td>
</tr>
<tr>
<td>2072</td>
<td>2328</td>
<td><a href="/research/cog/cog/COG0706/">COG0706</a></td>
<td>
M
</td>
<td>Membrane protein insertase Oxa1/YidC/SpoIIIJ</td>
</tr>
<tr>
<td>2064</td>
<td>2822</td>
<td><a href="/research/cog/cog/COG0707/">COG0707</a></td>
<td>
M
</td>
<td>UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase</td>
</tr>
<tr>
<td>1852</td>
<td>6321</td>
<td><a href="/research/cog/cog/COG0726/">COG0726</a></td>
<td>
M
G
</td>
<td>Peptidoglycan/xylan/chitin deacetylase, PgdA/NodB/CDA1 family</td>
</tr>
<tr>
<td>1617</td>
<td>1981</td>
<td><a href="/research/cog/cog/COG0728/">COG0728</a></td>
<td>
M
</td>
<td>Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis)</td>
</tr>
<tr>
<td>803</td>
<td>899</td>
<td><a href="/research/cog/cog/COG0729/">COG0729</a></td>
<td>
M
</td>
<td>Outer membrane translocation and assembly module TamA</td>
</tr>
<tr>
<td>1814</td>
<td>5282</td>
<td><a href="/research/cog/cog/COG0739/">COG0739</a></td>
<td>
M
</td>
<td>Murein endopeptidase or hydrolase activator MepM/NlpD, contains LysM domain</td>
</tr>
<tr>
<td>1556</td>
<td>4304</td>
<td><a href="/research/cog/cog/COG0741/">COG0741</a></td>
<td>
M
U
</td>
<td>Soluble lytic murein transglycosylase or regulatory protein ( may contain LysM/invasin domain), , includes type III secretion system proteins IagB/IpgF/YsaH</td>
</tr>
<tr>
<td>1715</td>
<td>3543</td>
<td><a href="/research/cog/cog/COG0744/">COG0744</a></td>
<td>
M
</td>
<td>Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase</td>
</tr>
<tr>
<td>1943</td>
<td>2056</td>
<td><a href="/research/cog/cog/COG0759/">COG0759</a></td>
<td>
M
</td>
<td>Membrane-anchored protein YidD, putatitve component of membrane protein insertase Oxa1/YidC/SpoIIIJ</td>
</tr>
<tr>
<td>1265</td>
<td>1359</td>
<td><a href="/research/cog/cog/COG0763/">COG0763</a></td>
<td>
M
</td>
<td>Lipid A disaccharide synthetase</td>
</tr>
<tr>
<td>2007</td>
<td>2445</td>
<td><a href="/research/cog/cog/COG0766/">COG0766</a></td>
<td>
M
</td>
<td>UDP-N-acetylglucosamine enolpyruvyl transferase</td>
</tr>
<tr>
<td>1343</td>
<td>2373</td>
<td><a href="/research/cog/cog/COG0767/">COG0767</a></td>
<td>
M
</td>
<td>Permease subunit MlaE of the ABC-type intermembrane phospholipid transporter Mla</td>
</tr>
<tr>
<td>2023</td>
<td>5041</td>
<td><a href="/research/cog/cog/COG0768/">COG0768</a></td>
<td>
D
M
</td>
<td>Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2)</td>
</tr>
<tr>
<td>2044</td>
<td>3002</td>
<td><a href="/research/cog/cog/COG0769/">COG0769</a></td>
<td>
M
</td>
<td>UDP-N-acetylmuramyl tripeptide synthase</td>
</tr>
<tr>
<td>2055</td>
<td>2353</td>
<td><a href="/research/cog/cog/COG0770/">COG0770</a></td>
<td>
M
</td>
<td>UDP-N-acetylmuramyl pentapeptide synthase</td>
</tr>
<tr>
<td>2011</td>
<td>2067</td>
<td><a href="/research/cog/cog/COG0771/">COG0771</a></td>
<td>
M
</td>
<td>UDP-N-acetylmuramoylalanine-D-glutamate ligase</td>
</tr>
<tr>
<td>2009</td>
<td>2768</td>
<td><a href="/research/cog/cog/COG0773/">COG0773</a></td>
<td>
M
</td>
<td>UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family</td>
</tr>
<tr>
<td>1279</td>
<td>1295</td>
<td><a href="/research/cog/cog/COG0774/">COG0774</a></td>
<td>
M
</td>
<td>UDP-3-O-acyl-N-acetylglucosamine deacetylase</td>
</tr>
<tr>
<td>1941</td>
<td>2379</td>
<td><a href="/research/cog/cog/COG0787/">COG0787</a></td>
<td>
M
</td>
<td>Alanine racemase</td>
</tr>
<tr>
<td>1599</td>
<td>4245</td>
<td><a href="/research/cog/cog/COG0791/">COG0791</a></td>
<td>
M
</td>
<td>Cell wall-associated hydrolase, NlpC_P60 family</td>
</tr>
<tr>
<td>1416</td>
<td>1660</td>
<td><a href="/research/cog/cog/COG0794/">COG0794</a></td>
<td>
M
G
</td>
<td>D-arabinose 5-phosphate isomerase GutQ</td>
</tr>
<tr>
<td>1361</td>
<td>2725</td>
<td><a href="/research/cog/cog/COG0795/">COG0795</a></td>
<td>
M
N
</td>
<td>Lipopolysaccharide export LptBFGC system, permease protein LptF</td>
</tr>
<tr>
<td>1700</td>
<td>1779</td>
<td><a href="/research/cog/cog/COG0796/">COG0796</a></td>
<td>
M
</td>
<td>Glutamate racemase</td>
</tr>
<tr>
<td>1039</td>
<td>1452</td>
<td><a href="/research/cog/cog/COG0797/">COG0797</a></td>
<td>
M
</td>
<td>Peptidoglycan lytic transglycosylase RlpA, contains C-terminal SPOR domain</td>
</tr>
<tr>
<td>1307</td>
<td>4212</td>
<td><a href="/research/cog/cog/COG0810/">COG0810</a></td>
<td>
M
</td>
<td>Periplasmic protein TonB, links inner and outer membranes</td>
</tr>
<tr>
<td>2026</td>
<td>2114</td>
<td><a href="/research/cog/cog/COG0812/">COG0812</a></td>
<td>
M
</td>
<td>UDP-N-acetylenolpyruvoylglucosamine reductase</td>
</tr>
<tr>
<td>1404</td>
<td>1622</td>
<td><a href="/research/cog/cog/COG0815/">COG0815</a></td>
<td>
M
</td>
<td>Apolipoprotein N-acyltransferase</td>
</tr>
<tr>
<td>1465</td>
<td>1697</td>
<td><a href="/research/cog/cog/COG0836/">COG0836</a></td>
<td>
M
</td>
<td>Mannose-1-phosphate guanylyltransferase</td>
</tr>
<tr>
<td>1713</td>
<td>11708</td>
<td><a href="/research/cog/cog/COG0845/">COG0845</a></td>
<td>
V
M
</td>
<td>Multidrug efflux pump subunit AcrA (membrane-fusion protein)</td>
</tr>
<tr>
<td>1098</td>
<td>3450</td>
<td><a href="/research/cog/cog/COG0859/">COG0859</a></td>
<td>
M
</td>
<td>ADP-heptose:LPS heptosyltransferase</td>
</tr>
<tr>
<td>1758</td>
<td>3474</td>
<td><a href="/research/cog/cog/COG0860/">COG0860</a></td>
<td>
M
</td>
<td>N-acetylmuramoyl-L-alanine amidase</td>
</tr>
<tr>
<td>1705</td>
<td>2205</td>
<td><a href="/research/cog/cog/COG1004/">COG1004</a></td>
<td>
M
</td>
<td>UDP-glucose 6-dehydrogenase</td>
</tr>
<tr>
<td>1325</td>
<td>1516</td>
<td><a href="/research/cog/cog/COG1043/">COG1043</a></td>
<td>
M
</td>
<td>Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase</td>
</tr>
<tr>
<td>1463</td>
<td>1984</td>
<td><a href="/research/cog/cog/COG1044/">COG1044</a></td>
<td>
M
</td>
<td>UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase</td>
</tr>
<tr>
<td>576</td>
<td>722</td>
<td><a href="/research/cog/cog/COG1083/">COG1083</a></td>
<td>
M
</td>
<td>CMP-N-acetylneuraminic acid synthetase, NeuA/PseF family</td>
</tr>
<tr>
<td>1584</td>
<td>2869</td>
<td><a href="/research/cog/cog/COG1086/">COG1086</a></td>
<td>
M
</td>
<td>NDP-sugar epimerase, includes UDP-N-acetylglucosamine 4,6-dehydratase EpsC</td>
</tr>
<tr>
<td>1832</td>
<td>2385</td>
<td><a href="/research/cog/cog/COG1087/">COG1087</a></td>
<td>
M
</td>
<td>UDP-glucose 4-epimerase</td>
</tr>
<tr>
<td>1686</td>
<td>2037</td>
<td><a href="/research/cog/cog/COG1088/">COG1088</a></td>
<td>
M
</td>
<td>dTDP-D-glucose 4,6-dehydratase</td>
</tr>
<tr>
<td>926</td>
<td>1261</td>
<td><a href="/research/cog/cog/COG1089/">COG1089</a></td>
<td>
M
</td>
<td>GDP-D-mannose dehydratase</td>
</tr>
<tr>
<td>1578</td>
<td>2117</td>
<td><a href="/research/cog/cog/COG1091/">COG1091</a></td>
<td>
M
</td>
<td>dTDP-4-dehydrorhamnose reductase</td>
</tr>
<tr>
<td>1344</td>
<td>2000</td>
<td><a href="/research/cog/cog/COG1127/">COG1127</a></td>
<td>
M
</td>
<td>ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla</td>
</tr>
<tr>
<td>2159</td>
<td>13012</td>
<td><a href="/research/cog/cog/COG1132/">COG1132</a></td>
<td>
V
M
</td>
<td>ABC-type multidrug and LPS transport system, ATPase and permease component MsbA</td>
</tr>
<tr>
<td>2224</td>
<td>10649</td>
<td><a href="/research/cog/cog/COG1136/">COG1136</a></td>
<td>
M
</td>
<td>ABC-type lipoprotein targeting system ATPase component LolD</td>
</tr>
<tr>
<td>1352</td>
<td>1369</td>
<td><a href="/research/cog/cog/COG1137/">COG1137</a></td>
<td>
M
</td>
<td>ABC-type lipopolysaccharide export system, ATPase component</td>
</tr>
<tr>
<td>2035</td>
<td>3482</td>
<td><a href="/research/cog/cog/COG1181/">COG1181</a></td>
<td>
M
R
</td>
<td>D-alanine-D-alanine ligase or related ATP-grasp enzyme</td>
</tr>
<tr>
<td>1996</td>
<td>2332</td>
<td><a href="/research/cog/cog/COG1207/">COG1207</a></td>
<td>
M
</td>
<td>Bifunctional protein GlmU, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase</td>
</tr>
<tr>
<td>1563</td>
<td>3090</td>
<td><a href="/research/cog/cog/COG1208/">COG1208</a></td>
<td>
J
M
</td>
<td>NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis protein s</td>
</tr>
<tr>
<td>1723</td>
<td>2427</td>
<td><a href="/research/cog/cog/COG1209/">COG1209</a></td>
<td>
M
</td>
<td>dTDP-glucose pyrophosphorylase</td>
</tr>
<tr>
<td>1508</td>
<td>1845</td>
<td><a href="/research/cog/cog/COG1210/">COG1210</a></td>
<td>
M
</td>
<td>UTP-glucose-1-phosphate uridylyltransferase</td>
</tr>
<tr>
<td>1216</td>
<td>1279</td>
<td><a href="/research/cog/cog/COG1212/">COG1212</a></td>
<td>
M
</td>
<td>CMP-2-keto-3-deoxyoctulosonic acid synthetase</td>
</tr>
<tr>
<td>1160</td>
<td>1178</td>
<td><a href="/research/cog/cog/COG1286/">COG1286</a></td>
<td>
M
F
</td>
<td>Colicin V production accessory protein CvpA, regulator of purF expression and biofilm formation</td>
</tr>
<tr>
<td>837</td>
<td>1784</td>
<td><a href="/research/cog/cog/COG1292/">COG1292</a></td>
<td>
M
</td>
<td>Choline-glycine betaine transporter</td>
</tr>
<tr>
<td>798</td>
<td>2349</td>
<td><a href="/research/cog/cog/COG1316/">COG1316</a></td>
<td>
M
</td>
<td>Anionic cell wall polymer biosynthesis enzyme TagV/TagU, LytR-Cps2A-Psr (LCP) family (peptidoglycan teichoic acid transferase)</td>
</tr>
<tr>
<td>672</td>
<td>794</td>
<td><a href="/research/cog/cog/COG1346/">COG1346</a></td>
<td>
M
</td>
<td>Putative effector of murein hydrolase</td>
</tr>
<tr>
<td>796</td>
<td>1329</td>
<td><a href="/research/cog/cog/COG1368/">COG1368</a></td>
<td>
M
</td>
<td>Phosphoglycerol transferase MdoB/OpgB, AlkP superfamily</td>
</tr>
<tr>
<td>1259</td>
<td>3525</td>
<td><a href="/research/cog/cog/COG1376/">COG1376</a></td>
<td>
M
</td>
<td>Lipoprotein-anchoring transpeptidase ErfK/SrfK</td>
</tr>
<tr>
<td>1335</td>
<td>2778</td>
<td><a href="/research/cog/cog/COG1388/">COG1388</a></td>
<td>
M
</td>
<td>LysM repeat</td>
</tr>
<tr>
<td>1193</td>
<td>1830</td>
<td><a href="/research/cog/cog/COG1408/">COG1408</a></td>
<td>
M
R
</td>
<td>Phosphohydrolase of MPP superfamily, includes undecaprenyl diphosphate-linked teichoic acid hydrolase UpsH/YpbG</td>
</tr>
<tr>
<td>163</td>
<td>184</td>
<td><a href="/research/cog/cog/COG1422/">COG1422</a></td>
<td>
M
</td>
<td>Archaeal membrane insertase Oxa1/YidC</td>
</tr>
<tr>
<td>1293</td>
<td>1987</td>
<td><a href="/research/cog/cog/COG1434/">COG1434</a></td>
<td>
M
</td>
<td>Lipid carrier protein ElyC involved in cell wall biogenesis, DUF218 family</td>
</tr>
<tr>
<td>350</td>
<td>503</td>
<td><a href="/research/cog/cog/COG1442/">COG1442</a></td>
<td>
M
</td>
<td>Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase</td>
</tr>
<tr>
<td>1339</td>
<td>1409</td>
<td><a href="/research/cog/cog/COG1452/">COG1452</a></td>
<td>
M
</td>
<td>Lipopolysaccharide export system protein LptD/OstA, potential outer membrane flippase</td>
</tr>
<tr>
<td>1351</td>
<td>3170</td>
<td><a href="/research/cog/cog/COG1463/">COG1463</a></td>
<td>
M
</td>
<td>Periplasmic subunit MlaD of the ABC-type intermembrane phospholipid transporter Mla</td>
</tr>
<tr>
<td>1609</td>
<td>1642</td>
<td><a href="/research/cog/cog/COG1496/">COG1496</a></td>
<td>
M
F
</td>
<td>UDP-MurNAc-monopeptide hydrolase/purine nucleoside phosphorylase YfiH, contains laccase domain</td>
</tr>
<tr>
<td>1172</td>
<td>1291</td>
<td><a href="/research/cog/cog/COG1519/">COG1519</a></td>
<td>
M
</td>
<td>3-deoxy-D-manno-octulosonic-acid transferase</td>
</tr>
<tr>
<td>1229</td>
<td>3533</td>
<td><a href="/research/cog/cog/COG1520/">COG1520</a></td>
<td>
M
</td>
<td>Outer membrane protein assembly factor BamB, contains beta-propeller repeat</td>
</tr>
<tr>
<td>1449</td>
<td>10050</td>
<td><a href="/research/cog/cog/COG1538/">COG1538</a></td>
<td>
M
</td>
<td>Outer membrane protein TolC</td>
</tr>
<tr>
<td>1837</td>
<td>1982</td>
<td><a href="/research/cog/cog/COG1559/">COG1559</a></td>
<td>
M
</td>
<td>Endolytic transglycosylase MltG, terminates peptidoglycan polymerization</td>
</tr>
<tr>
<td>1124</td>
<td>2562</td>
<td><a href="/research/cog/cog/COG1596/">COG1596</a></td>
<td>
M
</td>
<td>Periplasmic protein Wza involved in polysaccharide export, contains SLBB domain of the beta-grasp fold</td>
</tr>
<tr>
<td>960</td>
<td>1249</td>
<td><a href="/research/cog/cog/COG1619/">COG1619</a></td>
<td>
M
</td>
<td>Muramoyltetrapeptide carboxypeptidase LdcA (peptidoglycan recycling)</td>
</tr>
<tr>
<td>1176</td>
<td>1179</td>
<td><a href="/research/cog/cog/COG1663/">COG1663</a></td>
<td>
M
</td>
<td>Tetraacyldisaccharide-1-P 4&#x27;-kinase (Lipid A 4&#x27;-kinase)</td>
</tr>
<tr>
<td>1445</td>
<td>3167</td>
<td><a href="/research/cog/cog/COG1686/">COG1686</a></td>
<td>
M
</td>
<td>D-alanyl-D-alanine carboxypeptidase</td>
</tr>
<tr>
<td>790</td>
<td>1273</td>
<td><a href="/research/cog/cog/COG1696/">COG1696</a></td>
<td>
M
</td>
<td>D-alanyl-lipoteichoic acid acyltransferase DltB, MBOAT superfamily</td>
</tr>
<tr>
<td>1279</td>
<td>1611</td>
<td><a href="/research/cog/cog/COG1704/">COG1704</a></td>
<td>
M
</td>
<td>Magnetosome formation protein MamQ, lipoprotein antigen LemA family</td>
</tr>
<tr>
<td>666</td>
<td>911</td>
<td><a href="/research/cog/cog/COG1705/">COG1705</a></td>
<td>
M
N
</td>
<td>Flagellum-specific peptidoglycan hydrolase FlgJ</td>
</tr>
<tr>
<td>827</td>
<td>1108</td>
<td><a href="/research/cog/cog/COG1732/">COG1732</a></td>
<td>
M
</td>
<td>Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)</td>
</tr>
<tr>
<td>957</td>
<td>1046</td>
<td><a href="/research/cog/cog/COG1778/">COG1778</a></td>
<td>
M
R
</td>
<td>3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC and related HAD superfamily phosphatases</td>
</tr>
<tr>
<td>760</td>
<td>967</td>
<td><a href="/research/cog/cog/COG1794/">COG1794</a></td>
<td>
M
</td>
<td>Amino acid racemase YgeA</td>
</tr>
<tr>
<td>1239</td>
<td>2994</td>
<td><a href="/research/cog/cog/COG1807/">COG1807</a></td>
<td>
M
O
</td>
<td>PMT family glycosyltransferase ArnT/Agl22, involved in glycosylation of proteins and lipid IVA</td>
</tr>
<tr>
<td>13</td>
<td>21</td>
<td><a href="/research/cog/cog/COG1822/">COG1822</a></td>
<td>
M
</td>
<td>Uncharacterized membrane protein MJ0419, predicted role in archaeal polysaccharide biosynthesis</td>
</tr>
<tr>
<td>1228</td>
<td>3354</td>
<td><a href="/research/cog/cog/COG1835/">COG1835</a></td>
<td>
M
</td>
<td>Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains</td>
</tr>
<tr>
<td>915</td>
<td>1270</td>
<td><a href="/research/cog/cog/COG1842/">COG1842</a></td>
<td>
V
M
</td>
<td>Phage shock protein A involved in membrane remodeling, PspA/Vipp1/IM30 family</td>
</tr>
<tr>
<td>273</td>
<td>322</td>
<td><a href="/research/cog/cog/COG1861/">COG1861</a></td>
<td>
M
</td>
<td>Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family</td>
</tr>
<tr>
<td>762</td>
<td>1090</td>
<td><a href="/research/cog/cog/COG1876/">COG1876</a></td>
<td>
M
</td>
<td>LD-carboxypeptidase LdcB, LAS superfamily</td>
</tr>
<tr>
<td>451</td>
<td>881</td>
<td><a href="/research/cog/cog/COG1887/">COG1887</a></td>
<td>
M
I
</td>
<td>CDP-glycerol glycerophosphotransferase, TagB/SpsB family</td>
</tr>
<tr>
<td>1575</td>
<td>2168</td>
<td><a href="/research/cog/cog/COG1898/">COG1898</a></td>
<td>
M
</td>
<td>dTDP-4-dehydrorhamnose 3,5-epimerase or related enzyme</td>
</tr>
<tr>
<td>973</td>
<td>1265</td>
<td><a href="/research/cog/cog/COG1922/">COG1922</a></td>
<td>
M
</td>
<td>UDP-N-acetyl-D-mannosaminuronic acid transferase, WecB/TagA/CpsF family</td>
</tr>
<tr>
<td>1070</td>
<td>1090</td>
<td><a href="/research/cog/cog/COG1934/">COG1934</a></td>
<td>
M
</td>
<td>Lipopolysaccharide export system protein LptA</td>
</tr>
<tr>
<td>1384</td>
<td>1479</td>
<td><a href="/research/cog/cog/COG1970/">COG1970</a></td>
<td>
M
</td>
<td>Large-conductance mechanosensitive channel</td>
</tr>
<tr>
<td>1020</td>
<td>1272</td>
<td><a href="/research/cog/cog/COG2027/">COG2027</a></td>
<td>
M
</td>
<td>D-alanyl-D-alanine carboxypeptidase</td>
</tr>
<tr>
<td>558</td>
<td>656</td>
<td><a href="/research/cog/cog/COG2035/">COG2035</a></td>
<td>
M
</td>
<td>Undecaprenyl phosphate translocase (flippase), DUF368 family</td>
</tr>
<tr>
<td>370</td>
<td>383</td>
<td><a href="/research/cog/cog/COG2052/">COG2052</a></td>
<td>
M
</td>
<td>Regulator of extracellular matrix RemA, YlzA/DUF370 family</td>
</tr>
<tr>
<td>726</td>
<td>939</td>
<td><a href="/research/cog/cog/COG2089/">COG2089</a></td>
<td>
M
</td>
<td>Sialic acid synthase SpsE, contains C-terminal SAF domain</td>
</tr>
<tr>
<td>798</td>
<td>908</td>
<td><a href="/research/cog/cog/COG2103/">COG2103</a></td>
<td>
M
</td>
<td>N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase</td>
</tr>
<tr>
<td>1173</td>
<td>2497</td>
<td><a href="/research/cog/cog/COG2132/">COG2132</a></td>
<td>
D
M
P
</td>
<td>Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA)</td>
</tr>
<tr>
<td>1796</td>
<td>4115</td>
<td><a href="/research/cog/cog/COG2148/">COG2148</a></td>
<td>
M
</td>
<td>Sugar transferase involved in LPS biosynthesis (colanic, teichoic acid)</td>
</tr>
<tr>
<td>584</td>
<td>653</td>
<td><a href="/research/cog/cog/COG2173/">COG2173</a></td>
<td>
M
</td>
<td>D-alanyl-D-alanine dipeptidase</td>
</tr>
<tr>
<td>436</td>
<td>450</td>
<td><a href="/research/cog/cog/COG2179/">COG2179</a></td>
<td>
M
</td>
<td>Phosphatidylglycerophosphate phosphatase PgpP/YqeG or related phosphohydrolase, HAD superfamily</td>
</tr>
<tr>
<td>411</td>
<td>699</td>
<td><a href="/research/cog/cog/COG2194/">COG2194</a></td>
<td>
M
</td>
<td>Phosphoethanolamine transferase for periplasmic glucans OpgE, AlkP superfamily</td>
</tr>
<tr>
<td>562</td>
<td>789</td>
<td><a href="/research/cog/cog/COG2222/">COG2222</a></td>
<td>
M
</td>
<td>Fructoselysine-6-P-deglycase FrlB or related protein, duplicated sugar isomerase (SIS) domain</td>
</tr>
<tr>
<td>1811</td>
<td>4812</td>
<td><a href="/research/cog/cog/COG2244/">COG2244</a></td>
<td>
M
</td>
<td>Membrane protein involved in the export of O-antigen and teichoic acid</td>
</tr>
<tr>
<td>79</td>
<td>825</td>
<td><a href="/research/cog/cog/COG2247/">COG2247</a></td>
<td>
M
</td>
<td>Putative cell wall-binding domain (amidase enhancer), LytB superfamily</td>
</tr>
<tr>
<td>723</td>
<td>914</td>
<td><a href="/research/cog/cog/COG2327/">COG2327</a></td>
<td>
M
</td>
<td>Polysaccharide pyruvyl transferase family protein WcaK (colanic acid biosynthesis)</td>
</tr>
<tr>
<td>733</td>
<td>1483</td>
<td><a href="/research/cog/cog/COG2335/">COG2335</a></td>
<td>
M
</td>
<td>Surface protein containing fasciclin (FAS1) repeats</td>
</tr>
<tr>
<td>465</td>
<td>649</td>
<td><a href="/research/cog/cog/COG2348/">COG2348</a></td>
<td>
M
</td>
<td>Lipid II:glycine glycyltransferase (Peptidoglycan interpeptide bridge formation enzyme)</td>
</tr>
<tr>
<td>828</td>
<td>871</td>
<td><a href="/research/cog/cog/COG2363/">COG2363</a></td>
<td>
M
</td>
<td>Membrane protein YgdD, affects sensitivity to antimicrobial peptides, TMEM256/DUF423 family</td>
</tr>
<tr>
<td>1052</td>
<td>1072</td>
<td><a href="/research/cog/cog/COG2377/">COG2377</a></td>
<td>
M
</td>
<td>1,6-Anhydro-N-acetylmuramate kinase</td>
</tr>
<tr>
<td>575</td>
<td>944</td>
<td><a href="/research/cog/cog/COG2385/">COG2385</a></td>
<td>
D
M
</td>
<td>Sporulation protein SpoIID (lytic transglycosylase)</td>
</tr>
<tr>
<td>948</td>
<td>1607</td>
<td><a href="/research/cog/cog/COG2815/">COG2815</a></td>
<td>
M
</td>
<td>PASTA domain, binds beta-lactams</td>
</tr>
<tr>
<td>670</td>
<td>717</td>
<td><a href="/research/cog/cog/COG2821/">COG2821</a></td>
<td>
M
</td>
<td>Membrane-bound lytic murein transglycosylase</td>
</tr>
<tr>
<td>836</td>
<td>1713</td>
<td><a href="/research/cog/cog/COG2823/">COG2823</a></td>
<td>
M
</td>
<td>Phospholipid-binding membrane integrity protein DolP/YraP/OsmY, contains BON domain</td>
</tr>
<tr>
<td>1073</td>
<td>1441</td>
<td><a href="/research/cog/cog/COG2825/">COG2825</a></td>
<td>
M
O
</td>
<td>Periplasmic chaperone for outer membrane proteins, Skp/HlpA/OmpH family</td>
</tr>
<tr>
<td>357</td>
<td>378</td>
<td><a href="/research/cog/cog/COG2829/">COG2829</a></td>
<td>
M
</td>
<td>Outer membrane phospholipase A</td>
</tr>
<tr>
<td>1418</td>
<td>1784</td>
<td><a href="/research/cog/cog/COG2834/">COG2834</a></td>
<td>
M
</td>
<td>Periplasmic chaperone for outer membrane lipoprotein sorting</td>
</tr>
<tr>
<td>732</td>
<td>1019</td>
<td><a href="/research/cog/cog/COG2843/">COG2843</a></td>
<td>
M
</td>
<td>Poly-gamma-glutamate biosynthesis protein CapA/YwtB (capsule formation), metallophosphatase superfamily</td>
</tr>
<tr>
<td>177</td>
<td>210</td>
<td><a href="/research/cog/cog/COG2845/">COG2845</a></td>
<td>
M
</td>
<td>Peptidoglycan O-acetyltransferase, SGNH hydrolase family</td>
</tr>
<tr>
<td>706</td>
<td>786</td>
<td><a href="/research/cog/cog/COG2853/">COG2853</a></td>
<td>
M
</td>
<td>Outer membrane channel MlaA of the intermembrane phospholipid transporter MlaABCDEF complex</td>
</tr>
<tr>
<td>731</td>
<td>909</td>
<td><a href="/research/cog/cog/COG2854/">COG2854</a></td>
<td>
M
</td>
<td>Periplasmic subunit MlaC of the ABC-type intermembrane phospholipid transporter Mla</td>
</tr>
<tr>
<td>250</td>
<td>256</td>
<td><a href="/research/cog/cog/COG2859/">COG2859</a></td>
<td>
M
</td>
<td>Outer membrane channel-forming protein BP26/OMP28, SIMPL family</td>
</tr>
<tr>
<td>681</td>
<td>1010</td>
<td><a href="/research/cog/cog/COG2866/">COG2866</a></td>
<td>
M
</td>
<td>Murein tripeptide amidase MpaA</td>
</tr>
<tr>
<td>926</td>
<td>1460</td>
<td><a href="/research/cog/cog/COG2870/">COG2870</a></td>
<td>
M
</td>
<td>ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase</td>
</tr>
<tr>
<td>1200</td>
<td>1217</td>
<td><a href="/research/cog/cog/COG2877/">COG2877</a></td>
<td>
M
</td>
<td>3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase</td>
</tr>
<tr>
<td>1405</td>
<td>7590</td>
<td><a href="/research/cog/cog/COG2885/">COG2885</a></td>
<td>
M
</td>
<td>Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins</td>
</tr>
<tr>
<td>644</td>
<td>644</td>
<td><a href="/research/cog/cog/COG2891/">COG2891</a></td>
<td>
M
</td>
<td>Cell shape-determining protein MreD</td>
</tr>
<tr>
<td>1001</td>
<td>1377</td>
<td><a href="/research/cog/cog/COG2908/">COG2908</a></td>
<td>
M
</td>
<td>UDP-2,3-diacylglucosamine pyrophosphatase LpxH</td>
</tr>
<tr>
<td>795</td>
<td>920</td>
<td><a href="/research/cog/cog/COG2913/">COG2913</a></td>
<td>
M
</td>
<td>Outer membrane protein assembly factor BamE</td>
</tr>
<tr>
<td>374</td>
<td>427</td>
<td><a href="/research/cog/cog/COG2943/">COG2943</a></td>
<td>
M
G
</td>
<td>Membrane glycosyltransferase</td>
</tr>
<tr>
<td>446</td>
<td>492</td>
<td><a href="/research/cog/cog/COG2949/">COG2949</a></td>
<td>
M
</td>
<td>Uncharacterized periplasmic protein SanA, affects membrane permeability for vancomycin</td>
</tr>
<tr>
<td>967</td>
<td>1673</td>
<td><a href="/research/cog/cog/COG2951/">COG2951</a></td>
<td>
M
</td>
<td>Membrane-bound lytic murein transglycosylase B</td>
</tr>
<tr>
<td>925</td>
<td>1415</td>
<td><a href="/research/cog/cog/COG2956/">COG2956</a></td>
<td>
M
</td>
<td>Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain</td>
</tr>
<tr>
<td>489</td>
<td>489</td>
<td><a href="/research/cog/cog/COG2980/">COG2980</a></td>
<td>
M
</td>
<td>Lipopolysaccharide export system lipoprotein LptE/RlpB</td>
</tr>
<tr>
<td>807</td>
<td>1260</td>
<td><a href="/research/cog/cog/COG2982/">COG2982</a></td>
<td>
M
</td>
<td>Outer membrane assembly factor AsmA</td>
</tr>
<tr>
<td>572</td>
<td>840</td>
<td><a href="/research/cog/cog/COG2989/">COG2989</a></td>
<td>
M
</td>
<td>Murein L,D-transpeptidase YcbB/YkuD</td>
</tr>
<tr>
<td>454</td>
<td>758</td>
<td><a href="/research/cog/cog/COG2995/">COG2995</a></td>
<td>
M
</td>
<td>Intermembrane transporter PqiABC subunit PqiA</td>
</tr>
<tr>
<td>429</td>
<td>533</td>
<td><a href="/research/cog/cog/COG3008/">COG3008</a></td>
<td>
M
</td>
<td>Intermembrane transporter PqiABC subunit PqiB</td>
</tr>
<tr>
<td>393</td>
<td>437</td>
<td><a href="/research/cog/cog/COG3009/">COG3009</a></td>
<td>
M
</td>
<td>Intermembrane transporter PqiABC lipoprotein subunit PqiC</td>
</tr>
<tr>
<td>191</td>
<td>208</td>
<td><a href="/research/cog/cog/COG3015/">COG3015</a></td>
<td>
V
M
</td>
<td>Uncharacterized lipoprotein NlpE involved in copper resistance</td>
</tr>
<tr>
<td>466</td>
<td>467</td>
<td><a href="/research/cog/cog/COG3017/">COG3017</a></td>
<td>
M
</td>
<td>Outer membrane lipoprotein LolB, involved in outer membrane biogenesis</td>
</tr>
<tr>
<td>1126</td>
<td>1566</td>
<td><a href="/research/cog/cog/COG3023/">COG3023</a></td>
<td>
M
</td>
<td>N-acetyl-anhydromuramyl-L-alanine amidase AmpD</td>
</tr>
<tr>
<td>615</td>
<td>793</td>
<td><a href="/research/cog/cog/COG3034/">COG3034</a></td>
<td>
M
</td>
<td>Murein L,D-transpeptidase YafK</td>
</tr>
<tr>
<td>446</td>
<td>523</td>
<td><a href="/research/cog/cog/COG3040/">COG3040</a></td>
<td>
M
</td>
<td>Bacterial lipocalin Blc</td>
</tr>
<tr>
<td>491</td>
<td>626</td>
<td><a href="/research/cog/cog/COG3047/">COG3047</a></td>
<td>
M
</td>
<td>Outer membrane protein OmpW</td>
</tr>
<tr>
<td>418</td>
<td>578</td>
<td><a href="/research/cog/cog/COG3049/">COG3049</a></td>
<td>
M
R
</td>
<td>Penicillin V acylase or related amidase, Ntn superfamily</td>
</tr>
<tr>
<td>345</td>
<td>590</td>
<td><a href="/research/cog/cog/COG3055/">COG3055</a></td>
<td>
M
</td>
<td>N-acetylneuraminic acid mutarotase</td>
</tr>
<tr>
<td>673</td>
<td>1037</td>
<td><a href="/research/cog/cog/COG3064/">COG3064</a></td>
<td>
M
</td>
<td>Membrane protein TolA involved in colicin uptake</td>
</tr>
<tr>
<td>178</td>
<td>244</td>
<td><a href="/research/cog/cog/COG3065/">COG3065</a></td>
<td>
M
</td>
<td>Starvation-inducible outer membrane lipoprotein Slp</td>
</tr>
<tr>
<td>297</td>
<td>299</td>
<td><a href="/research/cog/cog/COG3079/">COG3079</a></td>
<td>
M
</td>
<td>Regulator of beta-lactam resistance, interacts with AlpA, YgfB/UPF0149 family</td>
</tr>
<tr>
<td>208</td>
<td>238</td>
<td><a href="/research/cog/cog/COG3083/">COG3083</a></td>
<td>
T
M
</td>
<td>Periplasmic protein PbgA/YejM, regulator of the LPS biosynthesis, AlkP superfamily</td>
</tr>
<tr>
<td>373</td>
<td>378</td>
<td><a href="/research/cog/cog/COG3107/">COG3107</a></td>
<td>
M
</td>
<td>Outer membrane lipoprotein LpoA, binds and activates PBP1a</td>
</tr>
<tr>
<td>530</td>
<td>737</td>
<td><a href="/research/cog/cog/COG3108/">COG3108</a></td>
<td>
M
</td>
<td>Metallopeptidase MepK/YcbK, cleaves mDAP crosslinks in peptidoglycan, peptidase M15/DUF882 family</td>
</tr>
<tr>
<td>509</td>
<td>653</td>
<td><a href="/research/cog/cog/COG3113/">COG3113</a></td>
<td>
M
</td>
<td>MlaB (STAS domain) subunit of the ABC-type intermembrane phospholipid transporter Mla</td>
</tr>
<tr>
<td>601</td>
<td>603</td>
<td><a href="/research/cog/cog/COG3117/">COG3117</a></td>
<td>
M
</td>
<td>Lipopolysaccharide export system protein LptC</td>
</tr>
<tr>
<td>341</td>
<td>533</td>
<td><a href="/research/cog/cog/COG3131/">COG3131</a></td>
<td>
M
</td>
<td>Periplasmic glucan biosynthesis protein OpgG</td>
</tr>
<tr>
<td>325</td>
<td>398</td>
<td><a href="/research/cog/cog/COG3133/">COG3133</a></td>
<td>
M
</td>
<td>Outer membrane lipoprotein SlyB</td>
</tr>
<tr>
<td>383</td>
<td>461</td>
<td><a href="/research/cog/cog/COG3137/">COG3137</a></td>
<td>
M
</td>
<td>Putative salt-induced outer membrane protein YdiY</td>
</tr>
<tr>
<td>608</td>
<td>626</td>
<td><a href="/research/cog/cog/COG3164/">COG3164</a></td>
<td>
M
</td>
<td>Phospholipid transporter to the outer membrane, contains AsmA2 domain</td>
</tr>
<tr>
<td>456</td>
<td>1806</td>
<td><a href="/research/cog/cog/COG3203/">COG3203</a></td>
<td>
M
</td>
<td>Outer membrane porin OmpC/OmpF/PhoE</td>
</tr>
<tr>
<td>1110</td>
<td>2709</td>
<td><a href="/research/cog/cog/COG3206/">COG3206</a></td>
<td>
M
</td>
<td>Tyrosine-protein kinase Wzc involved in exopolysaccharide export, GumC/Wzc1 domain</td>
</tr>
<tr>
<td>626</td>
<td>872</td>
<td><a href="/research/cog/cog/COG3238/">COG3238</a></td>
<td>
M
</td>
<td>Membrane protein involved in production of outer membrane vehicles,YdcZ/DUF606 family</td>
</tr>
<tr>
<td>163</td>
<td>193</td>
<td><a href="/research/cog/cog/COG3248/">COG3248</a></td>
<td>
M
</td>
<td>Nucleoside-specific outer membrane channel protein Tsx</td>
</tr>
<tr>
<td>461</td>
<td>642</td>
<td><a href="/research/cog/cog/COG3254/">COG3254</a></td>
<td>
M
</td>
<td>L-rhamnose mutarotase</td>
</tr>
<tr>
<td>1390</td>
<td>2777</td>
<td><a href="/research/cog/cog/COG3264/">COG3264</a></td>
<td>
M
</td>
<td>Small-conductance mechanosensitive channel MscK</td>
</tr>
<tr>
<td>284</td>
<td>348</td>
<td><a href="/research/cog/cog/COG3274/">COG3274</a></td>
<td>
M
</td>
<td>Surface polysaccharide O-acyltransferase WecH</td>
</tr>
<tr>
<td>276</td>
<td>397</td>
<td><a href="/research/cog/cog/COG3306/">COG3306</a></td>
<td>
M
</td>
<td>Glycosyltransferase involved in LPS biosynthesis, GR25 family</td>
</tr>
<tr>
<td>909</td>
<td>1339</td>
<td><a href="/research/cog/cog/COG3307/">COG3307</a></td>
<td>
M
</td>
<td>O-antigen ligase</td>
</tr>
<tr>
<td>428</td>
<td>436</td>
<td><a href="/research/cog/cog/COG3317/">COG3317</a></td>
<td>
M
</td>
<td>Outer membrane protein assembly factor BamC</td>
</tr>
<tr>
<td>928</td>
<td>2351</td>
<td><a href="/research/cog/cog/COG3409/">COG3409</a></td>
<td>
M
</td>
<td>Peptidoglycan-binding (PGRP) domain of peptidoglycan hydrolases</td>
</tr>
<tr>
<td>221</td>
<td>232</td>
<td><a href="/research/cog/cog/COG3417/">COG3417</a></td>
<td>
M
</td>
<td>Outer membrane lipoprotein LpoB, binds and activates PBP1b</td>
</tr>
<tr>
<td>375</td>
<td>377</td>
<td><a href="/research/cog/cog/COG3442/">COG3442</a></td>
<td>
M
H
</td>
<td>Glutaminase/glutamine amidotransferase domain of CobB, CobQ, and lipid II isoglutaminyl synthase</td>
</tr>
<tr>
<td>158</td>
<td>515</td>
<td><a href="/research/cog/cog/COG3468/">COG3468</a></td>
<td>
M
U
</td>
<td>Autotransporter adhesin AidA</td>
</tr>
<tr>
<td>137</td>
<td>142</td>
<td><a href="/research/cog/cog/COG3470/">COG3470</a></td>
<td>
M
I
</td>
<td>Uncharacterized conserved protein probably involved in high-affinity Fe2+ transport</td>
</tr>
<tr>
<td>440</td>
<td>443</td>
<td><a href="/research/cog/cog/COG3494/">COG3494</a></td>
<td>
M
</td>
<td>UDP-2,3-diacylglucosamine hydrolase LpxI, combines lipid X-binding and nucleotide phosphodiesterase domains</td>
</tr>
<tr>
<td>139</td>
<td>158</td>
<td><a href="/research/cog/cog/COG3510/">COG3510</a></td>
<td>
V
M
</td>
<td>Rhamnose/hydroxycephalosporin O-methyltransferase, CmcI/Rv2959c family</td>
</tr>
<tr>
<td>326</td>
<td>647</td>
<td><a href="/research/cog/cog/COG3511/">COG3511</a></td>
<td>
M
</td>
<td>Phospholipase C</td>
</tr>
<tr>
<td>292</td>
<td>388</td>
<td><a href="/research/cog/cog/COG3524/">COG3524</a></td>
<td>
M
</td>
<td>Capsule polysaccharide export protein KpsE/RkpR</td>
</tr>
<tr>
<td>219</td>
<td>251</td>
<td><a href="/research/cog/cog/COG3528/">COG3528</a></td>
<td>
M
</td>
<td>Lipid A deacylase LpxR, DUF2219 family</td>
</tr>
<tr>
<td>231</td>
<td>273</td>
<td><a href="/research/cog/cog/COG3562/">COG3562</a></td>
<td>
M
</td>
<td>Capsule polysaccharide modification protein KpsS</td>
</tr>
<tr>
<td>208</td>
<td>238</td>
<td><a href="/research/cog/cog/COG3563/">COG3563</a></td>
<td>
M
</td>
<td>Capsule polysaccharide export protein KpsC/LpsZ</td>
</tr>
<tr>
<td>148</td>
<td>215</td>
<td><a href="/research/cog/cog/COG3589/">COG3589</a></td>
<td>
M
</td>
<td>6-phospho-N-acetylmuramidase MupG, DUF871 family</td>
</tr>
<tr>
<td>460</td>
<td>1343</td>
<td><a href="/research/cog/cog/COG3637/">COG3637</a></td>
<td>
M
</td>
<td>Opacity protein LomR and related surface antigens</td>
</tr>
<tr>
<td>288</td>
<td>538</td>
<td><a href="/research/cog/cog/COG3659/">COG3659</a></td>
<td>
M
</td>
<td>Carbohydrate-selective porin OprB</td>
</tr>
<tr>
<td>421</td>
<td>659</td>
<td><a href="/research/cog/cog/COG3713/">COG3713</a></td>
<td>
M
</td>
<td>Outer membrane scaffolding protein for murein synthesis, MipA/OmpV family</td>
</tr>
<tr>
<td>260</td>
<td>359</td>
<td><a href="/research/cog/cog/COG3754/">COG3754</a></td>
<td>
M
</td>
<td>Lipopolysaccharide biosynthesis protein</td>
</tr>
<tr>
<td>537</td>
<td>896</td>
<td><a href="/research/cog/cog/COG3757/">COG3757</a></td>
<td>
M
</td>
<td>Lyzozyme M1 (1,4-beta-N-acetylmuramidase), GH25 family</td>
</tr>
<tr>
<td>594</td>
<td>1303</td>
<td><a href="/research/cog/cog/COG3764/">COG3764</a></td>
<td>
M
</td>
<td>Sortase (surface protein transpeptidase)</td>
</tr>
<tr>
<td>184</td>
<td>259</td>
<td><a href="/research/cog/cog/COG3765/">COG3765</a></td>
<td>
M
</td>
<td>LPS O-antigen chain length determinant protein, WzzB/FepE family</td>
</tr>
<tr>
<td>323</td>
<td>371</td>
<td><a href="/research/cog/cog/COG3770/">COG3770</a></td>
<td>
M
</td>
<td>Murein endopeptidase MepA (D-alanyl-D-alanine-endopeptidase)</td>
</tr>
<tr>
<td>142</td>
<td>142</td>
<td><a href="/research/cog/cog/COG3771/">COG3771</a></td>
<td>
M
</td>
<td>Lipopolysaccharide assembly protein YciS/LapA, DUF1049 family</td>
</tr>
<tr>
<td>390</td>
<td>644</td>
<td><a href="/research/cog/cog/COG3772/">COG3772</a></td>
<td>
M
</td>
<td>Phage-related lysozyme (muramidase), GH24 family</td>
</tr>
<tr>
<td>515</td>
<td>1028</td>
<td><a href="/research/cog/cog/COG3773/">COG3773</a></td>
<td>
D
M
</td>
<td>Cell wall hydrolase CwlJ, involved in spore germination</td>
</tr>
<tr>
<td>261</td>
<td>337</td>
<td><a href="/research/cog/cog/COG3774/">COG3774</a></td>
<td>
M
</td>
<td>Mannosyltransferase OCH1 or related enzyme</td>
</tr>
<tr>
<td>364</td>
<td>391</td>
<td><a href="/research/cog/cog/COG3786/">COG3786</a></td>
<td>
M
</td>
<td>L,D-peptidoglycan transpeptidase YkuD, ErfK/YbiS/YcfS/YnhG family</td>
</tr>
<tr>
<td>397</td>
<td>623</td>
<td><a href="/research/cog/cog/COG3875/">COG3875</a></td>
<td>
M
</td>
<td>Nickel-dependent lactate racemase</td>
</tr>
<tr>
<td>556</td>
<td>660</td>
<td><a href="/research/cog/cog/COG3876/">COG3876</a></td>
<td>
M
</td>
<td>Exo-beta-N-acetylmuramidase YbbC/NamZ, DUF1343 family</td>
</tr>
<tr>
<td>240</td>
<td>253</td>
<td><a href="/research/cog/cog/COG3895/">COG3895</a></td>
<td>
M
</td>
<td>Membrane-bound inhibitor of C-type lysozyme</td>
</tr>
<tr>
<td>339</td>
<td>504</td>
<td><a href="/research/cog/cog/COG3932/">COG3932</a></td>
<td>
M
</td>
<td>Exopolysaccharide synthesis protein ExoD</td>
</tr>
<tr>
<td>184</td>
<td>320</td>
<td><a href="/research/cog/cog/COG3942/">COG3942</a></td>
<td>
M
</td>
<td>Surface antigen</td>
</tr>
<tr>
<td>444</td>
<td>703</td>
<td><a href="/research/cog/cog/COG3944/">COG3944</a></td>
<td>
M
</td>
<td>Capsular polysaccharide biosynthesis protein YveK</td>
</tr>
<tr>
<td>33</td>
<td>34</td>
<td><a href="/research/cog/cog/COG3955/">COG3955</a></td>
<td>
M
</td>
<td>Uncharacterized conserved protein, DUF1919 family</td>
</tr>
<tr>
<td>86</td>
<td>91</td>
<td><a href="/research/cog/cog/COG3966/">COG3966</a></td>
<td>
M
</td>
<td>Poly-D-alanine transfer protein DltD, involved in esterification of teichoic acids</td>
</tr>
<tr>
<td>230</td>
<td>276</td>
<td><a href="/research/cog/cog/COG3967/">COG3967</a></td>
<td>
M
I
</td>
<td>Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids</td>
</tr>
<tr>
<td>342</td>
<td>368</td>
<td><a href="/research/cog/cog/COG3980/">COG3980</a></td>
<td>
M
</td>
<td>Spore coat polysaccharide biosynthesis protein SpsG, predicted glycosyltransferase</td>
</tr>
<tr>
<td>12</td>
<td>12</td>
<td><a href="/research/cog/cog/COG4092/">COG4092</a></td>
<td>
M
</td>
<td>Predicted glycosyltransferase involved in capsule biosynthesis</td>
</tr>
<tr>
<td>1250</td>
<td>1476</td>
<td><a href="/research/cog/cog/COG4105/">COG4105</a></td>
<td>
M
</td>
<td>Outer membrane protein assembly factor BamD, BamD/ComL family</td>
</tr>
<tr>
<td>101</td>
<td>108</td>
<td><a href="/research/cog/cog/COG4238/">COG4238</a></td>
<td>
M
</td>
<td>Outer membrane murein-binding lipoprotein Lpp</td>
</tr>
<tr>
<td>87</td>
<td>89</td>
<td><a href="/research/cog/cog/COG4267/">COG4267</a></td>
<td>
M
</td>
<td>PelG component of the PelDEFG exopolysaccharide exporter complex</td>
</tr>
<tr>
<td>108</td>
<td>140</td>
<td><a href="/research/cog/cog/COG4282/">COG4282</a></td>
<td>
M
</td>
<td>Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4)</td>
</tr>
<tr>
<td>54</td>
<td>64</td>
<td><a href="/research/cog/cog/COG4305/">COG4305</a></td>
<td>
M
</td>
<td>Peptidoglycan-binding domain, expansin YoaJ</td>
</tr>
<tr>
<td>212</td>
<td>322</td>
<td><a href="/research/cog/cog/COG4313/">COG4313</a></td>
<td>
M
</td>
<td>Sphingosine uptake channel SphA-related outer membrane channel</td>
</tr>
<tr>
<td>182</td>
<td>331</td>
<td><a href="/research/cog/cog/COG4409/">COG4409</a></td>
<td>
M
G
</td>
<td>Neuraminidase (sialidase) NanH, contains C-terminal autotransporter domain</td>
</tr>
<tr>
<td>233</td>
<td>371</td>
<td><a href="/research/cog/cog/COG4421/">COG4421</a></td>
<td>
M
</td>
<td>Predicted N-acetylglucosamine transferase involved in capsular polysaccharide biosynthesis, GT61 family</td>
</tr>
<tr>
<td>112</td>
<td>145</td>
<td><a href="/research/cog/cog/COG4424/">COG4424</a></td>
<td>
M
</td>
<td>LPS sulfotransferase NodH</td>
</tr>
<tr>
<td>201</td>
<td>272</td>
<td><a href="/research/cog/cog/COG4520/">COG4520</a></td>
<td>
M
</td>
<td>Surface antigen</td>
</tr>
<tr>
<td>60</td>
<td>68</td>
<td><a href="/research/cog/cog/COG4571/">COG4571</a></td>
<td>
M
</td>
<td>Outer membrane protease</td>
</tr>
<tr>
<td>39</td>
<td>42</td>
<td><a href="/research/cog/cog/COG4588/">COG4588</a></td>
<td>
M
</td>
<td>Accessory colonization factor AcfC, contains ABC-type periplasmic domain</td>
</tr>
<tr>
<td>2002</td>
<td>6487</td>
<td><a href="/research/cog/cog/COG4591/">COG4591</a></td>
<td>
M
</td>
<td>ABC-type lipoprotein targeting system transmembrane component LolC/LolE</td>
</tr>
<tr>
<td>638</td>
<td>954</td>
<td><a href="/research/cog/cog/COG4623/">COG4623</a></td>
<td>
T
M
</td>
<td>Membrane-bound lytic murein transglycosylase MltF</td>
</tr>
<tr>
<td>119</td>
<td>151</td>
<td><a href="/research/cog/cog/COG4678/">COG4678</a></td>
<td>
M
X
</td>
<td>Muramidase (phage lambda lysozyme), glycosyl transferase family 104</td>
</tr>
<tr>
<td>228</td>
<td>348</td>
<td><a href="/research/cog/cog/COG4692/">COG4692</a></td>
<td>
M
G
</td>
<td>Predicted neuraminidase (sialidase)</td>
</tr>
<tr>
<td>73</td>
<td>106</td>
<td><a href="/research/cog/cog/COG4750/">COG4750</a></td>
<td>
M
I
</td>
<td>CTP:phosphocholine cytidylyltransferase LicC</td>
</tr>
<tr>
<td>1402</td>
<td>2872</td>
<td><a href="/research/cog/cog/COG4775/">COG4775</a></td>
<td>
M
</td>
<td>Outer membrane protein assembly factor BamA</td>
</tr>
<tr>
<td>1572</td>
<td>6170</td>
<td><a href="/research/cog/cog/COG4783/">COG4783</a></td>
<td>
M
O
</td>
<td>Periplasmic chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains</td>
</tr>
<tr>
<td>331</td>
<td>399</td>
<td><a href="/research/cog/cog/COG4785/">COG4785</a></td>
<td>
M
</td>
<td>Lipoprotein NlpI, contains TPR repeats</td>
</tr>
<tr>
<td>333</td>
<td>378</td>
<td><a href="/research/cog/cog/COG4864/">COG4864</a></td>
<td>
M
</td>
<td>Flotillin-like protein FloA/YqfA, UPF0365 family</td>
</tr>
<tr>
<td>341</td>
<td>724</td>
<td><a href="/research/cog/cog/COG4932/">COG4932</a></td>
<td>
M
</td>
<td>Clumping factor A-related surface protein, MSCRAMM (microbial surface components recognizing adhesive matrix molecules) family, DEv-IgG fold</td>
</tr>
<tr>
<td>94</td>
<td>99</td>
<td><a href="/research/cog/cog/COG4939/">COG4939</a></td>
<td>
M
</td>
<td>Membrane-anchored lipoprotein Tpp15, contains FMN-binding domain</td>
</tr>
<tr>
<td>1481</td>
<td>5489</td>
<td><a href="/research/cog/cog/COG4948/">COG4948</a></td>
<td>
M
R
</td>
<td>L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily</td>
</tr>
<tr>
<td>316</td>
<td>353</td>
<td><a href="/research/cog/cog/COG4952/">COG4952</a></td>
<td>
M
</td>
<td>L-rhamnose isomerase</td>
</tr>
<tr>
<td>580</td>
<td>615</td>
<td><a href="/research/cog/cog/COG4953/">COG4953</a></td>
<td>
M
</td>
<td>Membrane carboxypeptidase/penicillin-binding protein PbpC</td>
</tr>
<tr>
<td>1183</td>
<td>1422</td>
<td><a href="/research/cog/cog/COG5009/">COG5009</a></td>
<td>
M
</td>
<td>Membrane carboxypeptidase/penicillin-binding protein</td>
</tr>
<tr>
<td>104</td>
<td>120</td>
<td><a href="/research/cog/cog/COG5039/">COG5039</a></td>
<td>
M
G
</td>
<td>Exopolysaccharide biosynthesis protein EpsI, predicted pyruvyl transferase</td>
</tr>
<tr>
<td>236</td>
<td>371</td>
<td><a href="/research/cog/cog/COG5337/">COG5337</a></td>
<td>
M
</td>
<td>Spore coat protein CotH</td>
</tr>
<tr>
<td>285</td>
<td>286</td>
<td><a href="/research/cog/cog/COG5375/">COG5375</a></td>
<td>
M
</td>
<td>Predicted lipopolysaccharide assembly protein, LptC/YrbK-like family</td>
</tr>
<tr>
<td>74</td>
<td>130</td>
<td><a href="/research/cog/cog/COG5435/">COG5435</a></td>
<td>
M
</td>
<td>Lipoprotein DcrB/SciW involved in osmoprotection and C1/C6 phage infection</td>
</tr>
<tr>
<td>150</td>
<td>286</td>
<td><a href="/research/cog/cog/COG5479/">COG5479</a></td>
<td>
M
</td>
<td>LGFP repeat-containing protein, may be involved in cell wall binding</td>
</tr>
<tr>
<td>290</td>
<td>556</td>
<td><a href="/research/cog/cog/COG5520/">COG5520</a></td>
<td>
M
</td>
<td>Glucuronoxylan xylanohydrolase XynC, GH30 family</td>
</tr>
<tr>
<td>179</td>
<td>181</td>
<td><a href="/research/cog/cog/COG5567/">COG5567</a></td>
<td>
M
</td>
<td>Periplasmic lipoprotein LptM/YifL, part of outer membrane beta-barrel assembly machinery</td>
</tr>
<tr>
<td>133</td>
<td>229</td>
<td><a href="/research/cog/cog/COG5577/">COG5577</a></td>
<td>
M
</td>
<td>Spore coat protein CotF</td>
</tr>
<tr>
<td>37</td>
<td>38</td>
<td><a href="/research/cog/cog/COG5597/">COG5597</a></td>
<td>
M
</td>
<td>N-acetylglucosaminyl transferase</td>
</tr>
<tr>
<td>303</td>
<td>343</td>
<td><a href="/research/cog/cog/COG5622/">COG5622</a></td>
<td>
M
</td>
<td>Protein required for attachment to host cells</td>
</tr>
<tr>
<td>172</td>
<td>290</td>
<td><a href="/research/cog/cog/COG5632/">COG5632</a></td>
<td>
M
</td>
<td>N-acetylmuramoyl-L-alanine amidase CwlA</td>
</tr>
<tr>
<td>95</td>
<td>95</td>
<td><a href="/research/cog/cog/COG6142/">COG6142</a></td>
<td>
M
</td>
<td>Membrane protein insertase subunit EMC6</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</section>
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