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<meta name="keywords" content="C4721429, familial nonmedullary thyroid cancer, papillary, neoplastic process, nkx2-1, nmtc1, nonmedullary thyroid carcinoma 1, nonmedullary thyroid carcinoma, papillary, papillary carcinoma of thyroid, thyroid cancer, nonmedullary, 1, thyroid cancer, nonmedullary, type 1, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin and accounts for more than 95% of all thyroid cancer cases. The remaining cancers originate from parafollicular cells (medullary thyroid cancer, MTC; 155240). NMTC is classified into 4 groups: papillary, follicular (188470), Hurthle cell (607464), and anaplastic. Approximately 5% of NMTC is hereditary, occurring as a component of a familial cancer syndrome (e.g., familial adenomatous polyposis, 175100; Carney complex, 160980) or as a primary feature (familial NMTC or FNMTC). Papillary thyroid cancer (PTC) is the most common histologic subtype of FNMTC, accounting for approximately 85% of cases (summary by Vriens et al., 2009). PTC is characterized by distinctive nuclear alterations including pseudoinclusions, grooves, and chromatin clearing. PTCs smaller than 1 cm are referred to as papillary microcarcinomas. These tumors have been identified in up to 35% of individuals at autopsy, suggesting that they may be extremely common although rarely clinically relevant. PTC can also be multifocal but is typically slow-growing with a tendency to spread to lymph nodes and usually has an excellent prognosis (summary by Bonora et al., 2010). Genetic Heterogeneity of Susceptibility to Nonmedullary Thyroid Cancer Other susceptibilities to nonmedullary thyroid cancer include NMTC2 (188470), caused by mutation in the SRGAP1 gene (606523); NMTC3 (606240), mapped to chromosome 2q21; NMTC4 (616534), caused by mutation in the FOXE1 gene (602617); and NMTC5 (616535), caused by mutation in the HABP2 gene (603924). A susceptibility locus for familial nonmedullary thyroid carcinoma with or without cell oxyphilia (TCO; 603386) has been mapped to chromosome 19p." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=1648293
|
||
ConceptID=C4721429
|
||
-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Thyroid cancer, nonmedullary, 1<span class="h1sub">(NMTC1)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648293</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4721429</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Nonmedullary thyroid carcinoma 1</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="NKX2-1 - ID: 7080 - NCBI Gene" href="/gene/7080" class="medgenPMinfo">NKX2-1</a> (14q13.3)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0008567" target="_blank">MONDO:0008567</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/188550" target="_blank">188550</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Nonmedullary thyroid cancer (NMTC) comprises thyroid cancers of follicular cell origin and accounts for more than 95% of all thyroid cancer cases. The remaining cancers originate from parafollicular cells (medullary thyroid cancer, MTC; 155240). NMTC is classified into 4 groups: papillary, follicular (188470), Hurthle cell (607464), and anaplastic. Approximately 5% of NMTC is hereditary, occurring as a component of a familial cancer syndrome (e.g., familial adenomatous polyposis, 175100; Carney complex, 160980) or as a primary feature (familial NMTC or FNMTC). Papillary thyroid cancer (PTC) is the most common histologic subtype of FNMTC, accounting for approximately 85% of cases (summary by Vriens et al., 2009). PTC is characterized by distinctive nuclear alterations including pseudoinclusions, grooves, and chromatin clearing. PTCs smaller than 1 cm are referred to as papillary microcarcinomas. These tumors have been identified in up to 35% of individuals at autopsy, suggesting that they may be extremely common although rarely clinically relevant. PTC can also be multifocal but is typically slow-growing with a tendency to spread to lymph nodes and usually has an excellent prognosis (summary by Bonora et al., 2010). Genetic Heterogeneity of Susceptibility to Nonmedullary Thyroid Cancer Other susceptibilities to nonmedullary thyroid cancer include NMTC2 (188470), caused by mutation in the SRGAP1 gene (606523); NMTC3 (606240), mapped to chromosome 2q21; NMTC4 (616534), caused by mutation in the FOXE1 gene (602617); and NMTC5 (616535), caused by mutation in the HABP2 gene (603924). A susceptibility locus for familial nonmedullary thyroid carcinoma with or without cell oxyphilia (TCO; 603386) has been mapped to chromosome 19p. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_66773"><div><strong>Papillary thyroid carcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66773</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0238463</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a papillary adenocarcinoma of the thyroid gland.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/66773">Feature record</a> | <a href="/medgen?term=%22Papillary%20thyroid%20carcinoma%22%5BClinical%20Features%5D%20OR%2066773%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_502247"><div><strong>Familial nonmedullary thyroid carcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>502247</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3501843</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare non-syndromic form of thyroid cancer characterized by occurrence of thyroid carcinoma (TC) as the primary feature in a familial setting.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/502247">Feature record</a> | <a href="/medgen?term=%22Familial%20nonmedullary%20thyroid%20carcinoma%22%5BClinical%20Features%5D%20OR%20502247%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_42270"><div><strong>Goiter</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>42270</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0018021</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An enlargement of the thyroid gland.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/42270">Feature record</a> | <a href="/medgen?term=%22Goiter%22%5BClinical%20Features%5D%20OR%2042270%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of the endocrine system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_42270" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Goiter</a></span></li></ul></li><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_502247" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial nonmedullary thyroid carcinoma</a></span></li><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_66773" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Papillary thyroid carcinoma</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35243857">Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Klubo-Gwiezdzinska J,
|
||
Wartofsky L</span><br />
|
||
<span class="medgenPMjournal">Pol Arch Intern Med</span>
|
||
2022 Mar 30;132(3)
|
||
Epub 2022 Mar 3
|
||
doi: 10.20452/pamw.16222.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35243857" target="_blank">35243857</a><a href="/pmc/articles/PMC9478900" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32491169">Contemporary Thyroid Nodule Evaluation and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grani G,
|
||
Sponziello M,
|
||
Pecce V,
|
||
Ramundo V,
|
||
Durante C</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2020 Sep 1;105(9):2869-83.
|
||
doi: 10.1210/clinem/dgaa322.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32491169" target="_blank">32491169</a><a href="/pmc/articles/PMC7365695" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25900731">Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Francis GL,
|
||
Waguespack SG,
|
||
Bauer AJ,
|
||
Angelos P,
|
||
Benvenga S,
|
||
Cerutti JM,
|
||
Dinauer CA,
|
||
Hamilton J,
|
||
Hay ID,
|
||
Luster M,
|
||
Parisi MT,
|
||
Rachmiel M,
|
||
Thompson GB,
|
||
Yamashita S;
|
||
American Thyroid Association Guidelines Task Force</span><br />
|
||
<span class="medgenPMjournal">Thyroid</span>
|
||
2015 Jul;25(7):716-59.
|
||
doi: 10.1089/thy.2014.0460.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25900731" target="_blank">25900731</a><a href="/pmc/articles/PMC4854274" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(thyroid%20cancer%2C%20nonmedullary%2C%201)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (451)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng230" target="_blank">UK NICE Guideline NG230, Thyroid cancer: assessment and management</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39354701">Joker Sign After Drooling Radioactive Saliva.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim M,
|
||
Han YH,
|
||
Jeong HJ,
|
||
Jeong JS,
|
||
Lim ST</span><br />
|
||
<span class="medgenPMjournal">Clin Nucl Med</span>
|
||
2025 Jan 1;50(1):96-97.
|
||
Epub 2024 Oct 2
|
||
doi: 10.1097/RLU.0000000000005449.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39354701" target="_blank">39354701</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37916932">Risk stratification of papillary thyroid cancers using multidimensional machine learning.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
|
||
Wu F,
|
||
Ge W,
|
||
Zhang Y,
|
||
Hu Y,
|
||
Zhao L,
|
||
Gou W,
|
||
Shi J,
|
||
Ni Y,
|
||
Li L,
|
||
Fu W,
|
||
Lin X,
|
||
Yu Y,
|
||
Han Z,
|
||
Chen C,
|
||
Xu R,
|
||
Zhang S,
|
||
Zhou L,
|
||
Pan G,
|
||
Peng Y,
|
||
Mao L,
|
||
Zhou T,
|
||
Zheng J,
|
||
Zheng H,
|
||
Sun Y,
|
||
Guo T,
|
||
Luo D</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2024 Jan 1;110(1):372-384.
|
||
doi: 10.1097/JS9.0000000000000814.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37916932" target="_blank">37916932</a><a href="/pmc/articles/PMC10793787" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33580435">Clinical features of pediatric familial non-medullary thyroid cancer (FNMTC).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Capezzone M,
|
||
Maino F,
|
||
Sagnella A,
|
||
Campanile M,
|
||
Dalmiglio C,
|
||
Pilli T,
|
||
Forleo R,
|
||
Castagna MG</span><br />
|
||
<span class="medgenPMjournal">J Endocrinol Invest</span>
|
||
2021 Oct;44(10):2319-2321.
|
||
Epub 2021 Feb 12
|
||
doi: 10.1007/s40618-021-01520-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33580435" target="_blank">33580435</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30872763">Association Between Radiomics Signature and Disease-Free Survival in Conventional Papillary Thyroid Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Park VY,
|
||
Han K,
|
||
Lee E,
|
||
Kim EK,
|
||
Moon HJ,
|
||
Yoon JH,
|
||
Kwak JY</span><br />
|
||
<span class="medgenPMjournal">Sci Rep</span>
|
||
2019 Mar 14;9(1):4501.
|
||
doi: 10.1038/s41598-018-37748-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30872763" target="_blank">30872763</a><a href="/pmc/articles/PMC6418281" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28942234">Second generation of familial nonmedullary thyroid carcinoma: A meta-analysis on the clinicopathologic features and prognosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou YM,
|
||
Luo H,
|
||
Gou JX,
|
||
Zhao WJ,
|
||
Dai WY,
|
||
Zhu J,
|
||
Li ZH</span><br />
|
||
<span class="medgenPMjournal">Eur J Surg Oncol</span>
|
||
2017 Dec;43(12):2248-2256.
|
||
Epub 2017 Sep 12
|
||
doi: 10.1016/j.ejso.2017.09.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28942234" target="_blank">28942234</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5280)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38478516">A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Han PZ,
|
||
Ye WD,
|
||
Yu PC,
|
||
Tan LC,
|
||
Shi X,
|
||
Chen XF,
|
||
He C,
|
||
Hu JQ,
|
||
Wei WJ,
|
||
Lu ZW,
|
||
Qu N,
|
||
Wang Y,
|
||
Ji QH,
|
||
Ji DM,
|
||
Wang YL</span><br />
|
||
<span class="medgenPMjournal">JCI Insight</span>
|
||
2024 Mar 7;9(8)
|
||
doi: 10.1172/jci.insight.173712.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38478516" target="_blank">38478516</a><a href="/pmc/articles/PMC11141884" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32968067">Lymph node metastasis prediction of papillary thyroid carcinoma based on transfer learning radiomics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu J,
|
||
Deng Y,
|
||
Liu T,
|
||
Zhou J,
|
||
Jia X,
|
||
Xiao T,
|
||
Zhou S,
|
||
Li J,
|
||
Guo Y,
|
||
Wang Y,
|
||
Zhou J,
|
||
Chang C</span><br />
|
||
<span class="medgenPMjournal">Nat Commun</span>
|
||
2020 Sep 23;11(1):4807.
|
||
doi: 10.1038/s41467-020-18497-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32968067" target="_blank">32968067</a><a href="/pmc/articles/PMC7511309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32866364">Thyroid Nodules: Advances in Evaluation and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kant R,
|
||
Davis A,
|
||
Verma V</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2020 Sep 1;102(5):298-304.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32866364" target="_blank">32866364</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30747050">Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ibrahimpasic T,
|
||
Ghossein R,
|
||
Shah JP,
|
||
Ganly I</span><br />
|
||
<span class="medgenPMjournal">Thyroid</span>
|
||
2019 Mar;29(3):311-321.
|
||
doi: 10.1089/thy.2018.0509.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30747050" target="_blank">30747050</a><a href="/pmc/articles/PMC6437626" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30322317">Black Thyroid.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu NY,
|
||
Gamez ME</span><br />
|
||
<span class="medgenPMjournal">Int J Surg Pathol</span>
|
||
2019 Jun;27(4):401-402.
|
||
Epub 2018 Sep 17
|
||
doi: 10.1177/1066896918800773.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30322317" target="_blank">30322317</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4226)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38478516">A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Han PZ,
|
||
Ye WD,
|
||
Yu PC,
|
||
Tan LC,
|
||
Shi X,
|
||
Chen XF,
|
||
He C,
|
||
Hu JQ,
|
||
Wei WJ,
|
||
Lu ZW,
|
||
Qu N,
|
||
Wang Y,
|
||
Ji QH,
|
||
Ji DM,
|
||
Wang YL</span><br />
|
||
<span class="medgenPMjournal">JCI Insight</span>
|
||
2024 Mar 7;9(8)
|
||
doi: 10.1172/jci.insight.173712.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38478516" target="_blank">38478516</a><a href="/pmc/articles/PMC11141884" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36449303">Comparison of Lobectomy vs Total Thyroidectomy for Intermediate-Risk Papillary Thyroid Carcinoma With Lymph Node Metastasis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu S,
|
||
Huang H,
|
||
Huang Y,
|
||
Qian J,
|
||
Wang X,
|
||
Xu Z,
|
||
Liu S,
|
||
Liu J</span><br />
|
||
<span class="medgenPMjournal">JAMA Surg</span>
|
||
2023 Jan 1;158(1):73-79.
|
||
doi: 10.1001/jamasurg.2022.5781.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36449303" target="_blank">36449303</a><a href="/pmc/articles/PMC9713681" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36326739">American Thyroid Association Guidelines and National Trends in Management of Papillary Thyroid Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gordon AJ,
|
||
Dublin JC,
|
||
Patel E,
|
||
Papazian M,
|
||
Chow MS,
|
||
Persky MJ,
|
||
Jacobson AS,
|
||
Patel KN,
|
||
Suh I,
|
||
Morris LGT,
|
||
Givi B</span><br />
|
||
<span class="medgenPMjournal">JAMA Otolaryngol Head Neck Surg</span>
|
||
2022 Dec 1;148(12):1156-1163.
|
||
doi: 10.1001/jamaoto.2022.3360.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36326739" target="_blank">36326739</a><a href="/pmc/articles/PMC9634599" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34237031">NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee YA,
|
||
Lee H,
|
||
Im SW,
|
||
Song YS,
|
||
Oh DY,
|
||
Kang HJ,
|
||
Won JK,
|
||
Jung KC,
|
||
Kwon D,
|
||
Chung EJ,
|
||
Hah JH,
|
||
Paeng JC,
|
||
Kim JH,
|
||
Choi J,
|
||
Kim OH,
|
||
Oh JM,
|
||
Ahn BC,
|
||
Wirth LJ,
|
||
Shin CH,
|
||
Kim JI,
|
||
Park YJ</span><br />
|
||
<span class="medgenPMjournal">J Clin Invest</span>
|
||
2021 Sep 15;131(18)
|
||
doi: 10.1172/JCI144847.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34237031" target="_blank">34237031</a><a href="/pmc/articles/PMC8439610" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30322317">Black Thyroid.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu NY,
|
||
Gamez ME</span><br />
|
||
<span class="medgenPMjournal">Int J Surg Pathol</span>
|
||
2019 Jun;27(4):401-402.
|
||
Epub 2018 Sep 17
|
||
doi: 10.1177/1066896918800773.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30322317" target="_blank">30322317</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1758)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38563672">Slow Growth, Excellent Prognosis: The Treatment and Overtreatment of Papillary Thyroid Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Georgiades C</span><br />
|
||
<span class="medgenPMjournal">Radiology</span>
|
||
2024 Apr;311(1):e240207.
|
||
doi: 10.1148/radiol.240207.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38563672" target="_blank">38563672</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37780815">Orthodenticle Homeobox OTX1 Promotes Papillary Thyroid Carcinoma Progression and Is a Potential Prognostic Biomarker.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Wei J,
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Wang X,
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Jiao K</span><br />
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<span class="medgenPMjournal">Genet Res (Camb)</span>
|
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2023;2023:5513812.
|
||
Epub 2023 Sep 21
|
||
doi: 10.1155/2023/5513812.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37780815" target="_blank">37780815</a><a href="/pmc/articles/PMC10539079" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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||
<div class="nl"><a target="_blank" href="/pubmed/35132899">Thyroid Cancer Incidence and Mortality Trends in the United States: 2000-2018.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Megwalu UC,
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Moon PK</span><br />
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<span class="medgenPMjournal">Thyroid</span>
|
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2022 May;32(5):560-570.
|
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Epub 2022 Mar 15
|
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doi: 10.1089/thy.2021.0662.
|
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<span class="bold">PMID: </span><a href="/pubmed/35132899" target="_blank">35132899</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/34663816">Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Pu W,
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Shi X,
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Yu P,
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Zhang M,
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Liu Z,
|
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Tan L,
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Han P,
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Wang Y,
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Ji D,
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Gan H,
|
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Wei W,
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Lu Z,
|
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Qu N,
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Hu J,
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Hu X,
|
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Luo Z,
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Li H,
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Ji Q,
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Wang J,
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Zhang X,
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Wang YL</span><br />
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<span class="medgenPMjournal">Nat Commun</span>
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2021 Oct 18;12(1):6058.
|
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doi: 10.1038/s41467-021-26343-3.
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<span class="bold">PMID: </span><a href="/pubmed/34663816" target="_blank">34663816</a><a href="/pmc/articles/PMC8523550" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/32866364">Thyroid Nodules: Advances in Evaluation and Management.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Kant R,
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Davis A,
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Verma V</span><br />
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<span class="medgenPMjournal">Am Fam Physician</span>
|
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2020 Sep 1;102(5):298-304.
|
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<span class="bold">PMID: </span><a href="/pubmed/32866364" target="_blank">32866364</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4145)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37916932">Risk stratification of papillary thyroid cancers using multidimensional machine learning.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
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Wu F,
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Ge W,
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Zhang Y,
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Hu Y,
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Zhao L,
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Gou W,
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Shi J,
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Ni Y,
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Li L,
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Fu W,
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Lin X,
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Yu Y,
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Han Z,
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Chen C,
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Xu R,
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Zhang S,
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Zhou L,
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Pan G,
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Peng Y,
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Mao L,
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Zhou T,
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Zheng J,
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Zheng H,
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Sun Y,
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Guo T,
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Luo D</span><br />
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<span class="medgenPMjournal">Int J Surg</span>
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2024 Jan 1;110(1):372-384.
|
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doi: 10.1097/JS9.0000000000000814.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37916932" target="_blank">37916932</a><a href="/pmc/articles/PMC10793787" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/36546348">Aggressive Subtypes of Papillary Thyroid Carcinoma Smaller Than 1 cm.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee JS,
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Lee JS,
|
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Yun HJ,
|
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Kim SM,
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Chang H,
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Lee YS,
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Chang HS,
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Park CS</span><br />
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<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
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2023 May 17;108(6):1370-1375.
|
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doi: 10.1210/clinem/dgac739.
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<span class="bold">PMID: </span><a href="/pubmed/36546348" target="_blank">36546348</a><a href="/pmc/articles/PMC10188299" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/32968067">Lymph node metastasis prediction of papillary thyroid carcinoma based on transfer learning radiomics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yu J,
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Deng Y,
|
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Liu T,
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Zhou J,
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Jia X,
|
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Xiao T,
|
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Zhou S,
|
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Li J,
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Guo Y,
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Wang Y,
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Zhou J,
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Chang C</span><br />
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<span class="medgenPMjournal">Nat Commun</span>
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2020 Sep 23;11(1):4807.
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doi: 10.1038/s41467-020-18497-3.
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<span class="bold">PMID: </span><a href="/pubmed/32968067" target="_blank">32968067</a><a href="/pmc/articles/PMC7511309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32866364">Thyroid Nodules: Advances in Evaluation and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kant R,
|
||
Davis A,
|
||
Verma V</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2020 Sep 1;102(5):298-304.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32866364" target="_blank">32866364</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30747050">Poorly Differentiated Carcinoma of the Thyroid Gland: Current Status and Future Prospects.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ibrahimpasic T,
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Ghossein R,
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Shah JP,
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Ganly I</span><br />
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<span class="medgenPMjournal">Thyroid</span>
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2019 Mar;29(3):311-321.
|
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doi: 10.1089/thy.2018.0509.
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<span class="bold">PMID: </span><a href="/pubmed/30747050" target="_blank">30747050</a><a href="/pmc/articles/PMC6437626" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3311)</a></div></div>
|
||
</div>
|
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|
||
<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38018310">Glucagon-like peptide-1 receptor agonists and risk of thyroid cancer: A systematic review and meta-analysis of randomized controlled trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Silverii GA,
|
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Monami M,
|
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Gallo M,
|
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Ragni A,
|
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Prattichizzo F,
|
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Renzelli V,
|
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Ceriello A,
|
||
Mannucci E</span><br />
|
||
<span class="medgenPMjournal">Diabetes Obes Metab</span>
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||
2024 Mar;26(3):891-900.
|
||
Epub 2023 Nov 29
|
||
doi: 10.1111/dom.15382.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38018310" target="_blank">38018310</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37604507">Efficacy and safety of ultrasound-guided radiofrequency, microwave and laser ablation for the treatment of T1N0M0 papillary thyroid carcinoma on a large scale: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gao X,
|
||
Yang Y,
|
||
Wang Y,
|
||
Huang Y</span><br />
|
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<span class="medgenPMjournal">Int J Hyperthermia</span>
|
||
2023 Dec;40(1):2244713.
|
||
doi: 10.1080/02656736.2023.2244713.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37604507" target="_blank">37604507</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35647194">Risk and Prognostic Factors for BRAF(V600E) Mutations in Papillary Thyroid Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wei X,
|
||
Wang X,
|
||
Xiong J,
|
||
Li C,
|
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Liao Y,
|
||
Zhu Y,
|
||
Mao J</span><br />
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<span class="medgenPMjournal">Biomed Res Int</span>
|
||
2022;2022:9959649.
|
||
Epub 2022 May 18
|
||
doi: 10.1155/2022/9959649.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35647194" target="_blank">35647194</a><a href="/pmc/articles/PMC9132653" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35142816">Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">van Dijk SPJ,
|
||
Coerts HI,
|
||
Gunput STG,
|
||
van Velsen EFS,
|
||
Medici M,
|
||
Moelker A,
|
||
Peeters RP,
|
||
Verhoef C,
|
||
van Ginhoven TM</span><br />
|
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<span class="medgenPMjournal">JAMA Otolaryngol Head Neck Surg</span>
|
||
2022 Apr 1;148(4):317-325.
|
||
doi: 10.1001/jamaoto.2021.4381.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35142816" target="_blank">35142816</a><a href="/pmc/articles/PMC8832309" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32477264">Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mao J,
|
||
Zhang Q,
|
||
Zhang H,
|
||
Zheng K,
|
||
Wang R,
|
||
Wang G</span><br />
|
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<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2020;11:265.
|
||
Epub 2020 May 15
|
||
doi: 10.3389/fendo.2020.00265.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32477264" target="_blank">32477264</a><a href="/pmc/articles/PMC7242632" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thyroid%20cancer%2C%20nonmedullary%2C%201%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (150)</a></div></div>
|
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|
||
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C4721429%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (5)</a></li>
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<li><a href="/gtr/tests?term=C4721429%5bDISCUI%5d&filter=method%3A2%5F12" target="_blank">Microsatellite instability testing (MSI) (1)</a></li>
|
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<li><a href="/gtr/tests?term=C4721429%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (1)</a></li>
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<li><a href="/gtr/tests?term=C4721429%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (6)</a></li>
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<li><a href="/gtr/tests?term=C4721429%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (7)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C4721429%5bDISCUI%5d" target="_blank">See all (16)</a></total></li>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(thyroid%20cancer%2C%20nonmedullary%2C%201)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng230">NICE, 2022</a><div>UK NICE Guideline NG230, Thyroid cancer: assessment and management</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=600635" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=7080[geneid]" target="_blank">View NKX2-1 variations in ClinVar</a></li><li><a href="/nuccore/262331562" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=188550" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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