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<meta name="keywords" content="C4024936, disease or syndrome, temporal cortical atrophy, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Atrophy of the temporal cortex." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=870489
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ConceptID=C4024936
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Temporal cortical atrophy</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>870489</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C4024936</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0007112">HP:0007112</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">Atrophy of the temporal cortex. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Temporal cortical atrophy</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/892343" ref="tree=MeSH" title="MedGen record for Morphological central nervous system abnormality">Morphological central nervous system abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/866738" ref="tree=MeSH" title="MedGen record for Abnormal brain morphology">Abnormal brain morphology</a></span><ul><li><span class="TLline"><a href="/medgen/866620" ref="tree=MeSH" title="MedGen record for Abnormal forebrain morphology">Abnormal forebrain morphology</a></span><ul><li><span class="TLline"><a href="/medgen/867394" ref="tree=MeSH" title="MedGen record for Abnormal cerebral morphology">Abnormal cerebral morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871221" ref="tree=MeSH" title="MedGen record for Abnormal cerebral cortex morphology">Abnormal cerebral cortex morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1646740" ref="tree=MeSH" title="MedGen record for Cerebral cortical atrophy">Cerebral cortical atrophy</a></span><ul><li><span class="matched_ds">Temporal cortical atrophy</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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||
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_376072"><div><strong>Alzheimer disease 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>376072</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1847200</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Alzheimer's disease is a degenerative disease of the brain that causes dementia, which is a gradual loss of memory, judgment, and ability to function. This disorder usually appears in people older than age 65, but less common forms of the disease appear earlier in adulthood.\n\nMemory loss is the most common sign of Alzheimer's disease. Forgetfulness may be subtle at first, but the loss of memory worsens over time until it interferes with most aspects of daily living. Even in familiar settings, a person with Alzheimer's disease may get lost or become confused. Routine tasks such as preparing meals, doing laundry, and performing other household chores can be challenging. Additionally, it may become difficult to recognize people and name objects. Affected people increasingly require help with dressing, eating, and personal care.\n\nAs the disorder progresses, some people with Alzheimer's disease experience personality and behavioral changes and have trouble interacting in a socially appropriate manner. Other common symptoms include agitation, restlessness, withdrawal, and loss of language skills. People with Alzheimer's disease usually require total care during the advanced stages of the disease.\n\nIndividuals with Alzheimer's disease usually survive 8 to 10 years after the appearance of symptoms, but the course of the disease can range from 1 to 25 years. Survival is usually shorter in individuals diagnosed after age 80 than in those diagnosed at a younger age. In Alzheimer's disease, death usually results from pneumonia, malnutrition, or general body wasting (inanition).\n\nAlzheimer's disease can be classified as early-onset or late-onset. The signs and symptoms of the early-onset form appear between a person's thirties and mid-sixties, while the late-onset form appears during or after a person's mid-sixties. The early-onset form of Alzheimer's disease is much less common than the late-onset form, accounting for less than 10 percent of all cases of Alzheimer's disease.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/376072">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816608"><div><strong>Joubert syndrome 22</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816608</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3810278</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Classic Joubert syndrome (JS) is characterized by three primary findings: A distinctive cerebellar and brain stem malformation called the molar tooth sign (MTS). Hypotonia. Developmental delays. Often these findings are accompanied by episodic tachypnea or apnea and/or atypical eye movements. In general, the breathing abnormalities improve with age, truncal ataxia develops over time, and acquisition of gross motor milestones is delayed. Cognitive abilities are variable, ranging from severe intellectual disability to normal. Additional findings can include retinal dystrophy, renal disease, ocular colobomas, occipital encephalocele, hepatic fibrosis, polydactyly, oral hamartomas, and endocrine abnormalities. Both intra- and interfamilial variation are seen.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816608">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1641069"><div><strong>Inclusion body myopathy with Paget disease of bone and frontotemporal dementia type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1641069</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551951</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Inclusion body myopathy associated with Paget disease of bone (PDB) and/or frontotemporal dementia (IBMPFD) is characterized by adult-onset proximal and distal muscle weakness (clinically resembling a limb-girdle muscular dystrophy syndrome), early-onset PDB, and premature frontotemporal dementia (FTD). Muscle weakness progresses to involve other limb and respiratory muscles. PDB involves focal areas of increased bone turnover that typically lead to spine and/or hip pain and localized enlargement and deformity of the long bones; pathologic fractures occur on occasion. Early stages of FTD are characterized by dysnomia, dyscalculia, comprehension deficits, and paraphasic errors, with minimal impairment of episodic memory; later stages are characterized by inability to speak, auditory comprehension deficits for even one-step commands, alexia, and agraphia. Mean age at diagnosis for muscle disease and PDB is 42 years; for FTD, 56 years. Dilated cardiomyopathy, amyotrophic lateral sclerosis, and Parkinson disease are now known to be part of the spectrum of findings associated with IBMPFD.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1641069">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1710110"><div><strong>Neurodevelopmental disorder with hypotonia, microcephaly, and seizures</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1710110</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5394312</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neurodevelopmental disorder with hypotonia, microcephaly, and seizures (NEDHYMS) is an autosomal recessive disorder characterized by global developmental delay with axial hypotonia, inability to sit or walk, and severely impaired intellectual development with absent language. Most patients develop early-onset intractable seizures that prevent normal development. Additional features include feeding difficulties with poor overall growth and microcephaly. Some patients may have spastic quadriplegia, poor eye contact due to cortical blindness, variable dysmorphic features, and nonspecific abnormalities on brain imaging (summary by Tan et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1710110">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_376072" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Alzheimer disease 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1641069" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Inclusion body myopathy with Paget disease of bone and frontotemporal dementia type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816608" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Joubert syndrome 22</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1710110" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with hypotonia, microcephaly, and seizures</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39135427">Methods for assessment of Rey Auditory Verbal Learning Test performance in memory clinic patients and healthy adults - at the cross-roads of learning theory and clinical utility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Almkvist O,
|
||
Rennie A,
|
||
Westman E,
|
||
Wallert J,
|
||
Ekman U</span><br />
|
||
<span class="medgenPMjournal">Clin Neuropsychol</span>
|
||
2025 Feb;39(2):424-438.
|
||
Epub 2024 Aug 12
|
||
doi: 10.1080/13854046.2024.2384616.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39135427" target="_blank">39135427</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22temporal%20cortical%20atrophy%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33667779">Fronto-temporal cortical atrophy in 'nyaope' combination heroin and cannabis use disorder.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ndlovu NA,
|
||
Morgan N,
|
||
Malapile S,
|
||
Subramaney U,
|
||
Daniels W,
|
||
Naidoo J,
|
||
van den Heuvel MP,
|
||
Calvey T</span><br />
|
||
<span class="medgenPMjournal">Drug Alcohol Depend</span>
|
||
2021 Apr 1;221:108630.
|
||
Epub 2021 Feb 16
|
||
doi: 10.1016/j.drugalcdep.2021.108630.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33667779" target="_blank">33667779</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29504533">Associations between the Frailty Index and Brain Atrophy: The Treviso Dementia (TREDEM) Registry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gallucci M,
|
||
Piovesan C,
|
||
Di Battista ME</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2018;62(4):1623-1634.
|
||
doi: 10.3233/JAD-170938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29504533" target="_blank">29504533</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27012504">Disease-specific patterns of cortical and subcortical degeneration in a longitudinal study of Alzheimer's disease and behavioural-variant frontotemporal dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Landin-Romero R,
|
||
Kumfor F,
|
||
Leyton CE,
|
||
Irish M,
|
||
Hodges JR,
|
||
Piguet O</span><br />
|
||
<span class="medgenPMjournal">Neuroimage</span>
|
||
2017 May 1;151:72-80.
|
||
Epub 2016 Mar 21
|
||
doi: 10.1016/j.neuroimage.2016.03.032.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27012504" target="_blank">27012504</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12397139">Long term outcome of temporal lobe epilepsy surgery: analyses of 140 consecutive patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jutila L,
|
||
Immonen A,
|
||
Mervaala E,
|
||
Partanen J,
|
||
Partanen K,
|
||
Puranen M,
|
||
Kälviäinen R,
|
||
Alafuzoff I,
|
||
Hurskainen H,
|
||
Vapalahti M,
|
||
Ylinen A</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
2002 Nov;73(5):486-94.
|
||
doi: 10.1136/jnnp.73.5.486.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12397139" target="_blank">12397139</a><a href="/pmc/articles/PMC1738104" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10567490">Clinical and radiological determinants of prestroke cognitive decline in a stroke cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pohjasvaara T,
|
||
Mäntylä R,
|
||
Aronen HJ,
|
||
Leskelä M,
|
||
Salonen O,
|
||
Kaste M,
|
||
Erkinjuntti T</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
1999 Dec;67(6):742-8.
|
||
doi: 10.1136/jnnp.67.6.742.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10567490" target="_blank">10567490</a><a href="/pmc/articles/PMC1736686" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Temporal%20cortical%20atrophy%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38702802">Combined in vivo MRI assessment of locus coeruleus and nucleus basalis of Meynert integrity in amnestic Alzheimer's disease, suspected-LATE and frontotemporal dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lagarde J,
|
||
Olivieri P,
|
||
Tonietto M,
|
||
Noiray C,
|
||
Lehericy S,
|
||
Valabrègue R,
|
||
Caillé F,
|
||
Gervais P,
|
||
Moussion M,
|
||
Bottlaender M,
|
||
Sarazin M</span><br />
|
||
<span class="medgenPMjournal">Alzheimers Res Ther</span>
|
||
2024 May 3;16(1):97.
|
||
doi: 10.1186/s13195-024-01466-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38702802" target="_blank">38702802</a><a href="/pmc/articles/PMC11067144" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37334599">Alzheimer's Disease and Neurosyphilis: Meaningful Commonalities and Differences of Clinical Phenotype and Pathophysiological Biomarkers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Milano C,
|
||
Hoxhaj D,
|
||
Del Chicca M,
|
||
Pascazio A,
|
||
Paoli D,
|
||
Tommasini L,
|
||
Vergallo A,
|
||
Pizzanelli C,
|
||
Tognoni G,
|
||
Nuti A,
|
||
Ceravolo R,
|
||
Siciliano G,
|
||
Hampel H,
|
||
Baldacci F;
|
||
Neurodegeneration Precision Medicine Initiative (NPMI)</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2023;94(2):611-625.
|
||
doi: 10.3233/JAD-230170.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37334599" target="_blank">37334599</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29504533">Associations between the Frailty Index and Brain Atrophy: The Treviso Dementia (TREDEM) Registry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gallucci M,
|
||
Piovesan C,
|
||
Di Battista ME</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2018;62(4):1623-1634.
|
||
doi: 10.3233/JAD-170938.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29504533" target="_blank">29504533</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27012504">Disease-specific patterns of cortical and subcortical degeneration in a longitudinal study of Alzheimer's disease and behavioural-variant frontotemporal dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Landin-Romero R,
|
||
Kumfor F,
|
||
Leyton CE,
|
||
Irish M,
|
||
Hodges JR,
|
||
Piguet O</span><br />
|
||
<span class="medgenPMjournal">Neuroimage</span>
|
||
2017 May 1;151:72-80.
|
||
Epub 2016 Mar 21
|
||
doi: 10.1016/j.neuroimage.2016.03.032.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27012504" target="_blank">27012504</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15079017">Dissociation of numbers and objects in corticobasal degeneration and semantic dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Halpern CH,
|
||
Glosser G,
|
||
Clark R,
|
||
Gee J,
|
||
Moore P,
|
||
Dennis K,
|
||
McMillan C,
|
||
Colcher A,
|
||
Grossman M</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2004 Apr 13;62(7):1163-9.
|
||
doi: 10.1212/01.wnl.0000118209.95423.96.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15079017" target="_blank">15079017</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Temporal%20cortical%20atrophy%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37334599">Alzheimer's Disease and Neurosyphilis: Meaningful Commonalities and Differences of Clinical Phenotype and Pathophysiological Biomarkers.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Milano C,
|
||
Hoxhaj D,
|
||
Del Chicca M,
|
||
Pascazio A,
|
||
Paoli D,
|
||
Tommasini L,
|
||
Vergallo A,
|
||
Pizzanelli C,
|
||
Tognoni G,
|
||
Nuti A,
|
||
Ceravolo R,
|
||
Siciliano G,
|
||
Hampel H,
|
||
Baldacci F;
|
||
Neurodegeneration Precision Medicine Initiative (NPMI)</span><br />
|
||
<span class="medgenPMjournal">J Alzheimers Dis</span>
|
||
2023;94(2):611-625.
|
||
doi: 10.3233/JAD-230170.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37334599" target="_blank">37334599</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30796080">Fulminant thymomatous AMPAR-antibody limbic encephalitis with hypertonic coma, bruxism, an isoelectric electroencephalogram and temporal cortical atrophy, with recovery.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Urriola N,
|
||
Soosapilla K,
|
||
Drummond J,
|
||
Thieben M</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2019 Feb 21;12(2)
|
||
doi: 10.1136/bcr-2018-227893.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30796080" target="_blank">30796080</a><a href="/pmc/articles/PMC6388879" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9043743">Regional HmPAO SPECT and CT measurements in the diagnosis of Alzheimer's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mattman A,
|
||
Feldman H,
|
||
Forster B,
|
||
Li D,
|
||
Szasz I,
|
||
Beattie BL,
|
||
Schulzer M</span><br />
|
||
<span class="medgenPMjournal">Can J Neurol Sci</span>
|
||
1997 Feb;24(1):22-8.
|
||
doi: 10.1017/s0317167100021041.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9043743" target="_blank">9043743</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Temporal%20cortical%20atrophy%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/22405087">Infantile cerebellar-retinal degeneration associated with a mutation in mitochondrial aconitase, ACO2.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Spiegel R,
|
||
Pines O,
|
||
Ta-Shma A,
|
||
Burak E,
|
||
Shaag A,
|
||
Halvardson J,
|
||
Edvardson S,
|
||
Mahajna M,
|
||
Zenvirt S,
|
||
Saada A,
|
||
Shalev S,
|
||
Feuk L,
|
||
Elpeleg O</span><br />
|
||
<span class="medgenPMjournal">Am J Hum Genet</span>
|
||
2012 Mar 9;90(3):518-23.
|
||
doi: 10.1016/j.ajhg.2012.01.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22405087" target="_blank">22405087</a><a href="/pmc/articles/PMC3309186" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12397139">Long term outcome of temporal lobe epilepsy surgery: analyses of 140 consecutive patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jutila L,
|
||
Immonen A,
|
||
Mervaala E,
|
||
Partanen J,
|
||
Partanen K,
|
||
Puranen M,
|
||
Kälviäinen R,
|
||
Alafuzoff I,
|
||
Hurskainen H,
|
||
Vapalahti M,
|
||
Ylinen A</span><br />
|
||
<span class="medgenPMjournal">J Neurol Neurosurg Psychiatry</span>
|
||
2002 Nov;73(5):486-94.
|
||
doi: 10.1136/jnnp.73.5.486.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12397139" target="_blank">12397139</a><a href="/pmc/articles/PMC1738104" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9728730">Early-onset Alzheimer's disease due to mutations of the presenilin-1 gene on chromosome 14: a 7-year follow-up of a patient with a mutation at codon 139.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hüll M,
|
||
Fiebich BL,
|
||
Dykierek P,
|
||
Schmidtke K,
|
||
Nitzsche E,
|
||
Orszagh M,
|
||
Deuschl G,
|
||
Moser E,
|
||
Schumacher M,
|
||
Lücking C,
|
||
Berger M,
|
||
Bauer J</span><br />
|
||
<span class="medgenPMjournal">Eur Arch Psychiatry Clin Neurosci</span>
|
||
1998;248(3):123-9.
|
||
doi: 10.1007/s004060050028.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9728730" target="_blank">9728730</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Temporal%20cortical%20atrophy%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38702802">Combined in vivo MRI assessment of locus coeruleus and nucleus basalis of Meynert integrity in amnestic Alzheimer's disease, suspected-LATE and frontotemporal dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lagarde J,
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Olivieri P,
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Tonietto M,
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Noiray C,
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Lehericy S,
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Valabrègue R,
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Caillé F,
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Gervais P,
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2024 May 3;16(1):97.
|
||
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|
||
<span class="bold">PMID: </span><a href="/pubmed/38702802" target="_blank">38702802</a><a href="/pmc/articles/PMC11067144" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29504533">Associations between the Frailty Index and Brain Atrophy: The Treviso Dementia (TREDEM) Registry.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gallucci M,
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<span class="bold">PMID: </span><a href="/pubmed/29504533" target="_blank">29504533</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/26437767">Epilepsy is a possible feature in Williams-Beuren syndrome patients harboring typical deletions of the 7q11.23 critical region.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Nicita F,
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Garone G,
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Spalice A,
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Savasta S,
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Spartà MV,
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Kluger G,
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Epub 2015 Oct 5
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|
||
<span class="bold">PMID: </span><a href="/pubmed/26437767" target="_blank">26437767</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/15852395">Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grossman M,
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Farmer J,
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Leight S,
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Work M,
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Pratico D,
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Coslett HB,
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2005 May;57(5):721-9.
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|
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<span class="bold">PMID: </span><a href="/pubmed/15852395" target="_blank">15852395</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/12397139">Long term outcome of temporal lobe epilepsy surgery: analyses of 140 consecutive patients.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Jutila L,
|
||
Immonen A,
|
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Mervaala E,
|
||
Partanen J,
|
||
Partanen K,
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Puranen M,
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Kälviäinen R,
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Alafuzoff I,
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2002 Nov;73(5):486-94.
|
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|
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<span class="bold">PMID: </span><a href="/pubmed/12397139" target="_blank">12397139</a><a href="/pmc/articles/PMC1738104" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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