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<meta name="keywords" content="C3276706, disease or syndrome, neuropathies, small fiber, neuropathies, small fibre, neuropathy, small fiber, neuropathy, small fibre, painful peripheral neuropathy small nerve fiber neuropathy, sfnp, sfnp - small fiber neuropathy, small fiber neuropathies, small fiber neuropathy, small fibre neuropathies, small fibre neuropathy, small nerve fiber neuropathy, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Small fiber neuropathy is a condition characterized by severe pain attacks that typically begin in the feet or hands. As a person ages, the pain attacks can affect other regions. Some people initially experience a more generalized, whole-body pain. The attacks usually consist of pain described as stabbing or burning, or abnormal skin sensations such as tingling or itchiness. In some individuals, the pain is more severe during times of rest or at night. The signs and symptoms of small fiber neuropathy usually begin in adolescence to mid-adulthood.\n\nIndividuals with small fiber neuropathy cannot feel pain that is concentrated in a very small area, such as the prick of a pin. However, they have an increased sensitivity to pain in general (hyperalgesia) and experience pain from stimulation that typically does not cause pain (allodynia). People affected with this condition may also have a reduced ability to differentiate between hot and cold. However, in some individuals, the pain attacks are provoked by cold or warm triggers.\n\nSome affected individuals have urinary or bowel problems, episodes of rapid heartbeat (palpitations), dry eyes or mouth, or abnormal sweating. They can also experience a sharp drop in blood pressure upon standing (orthostatic hypotension), which can cause dizziness, blurred vision, or fainting.\n\nSmall fiber neuropathy is considered a form of peripheral neuropathy because it affects the peripheral nervous system, which connects the brain and spinal cord to muscles and to cells that detect sensations such as touch, smell, and pain." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Small fiber neuropathy (Concept Id: C3276706)
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<!--
UID=478336
ConceptID=C3276706
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Small fiber neuropathy<span class="h1sub">(SFNP)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>478336</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C3276706</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>SFNP</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Small fiber neuropathy (709489006); Small nerve fiber neuropathy (709489006); SFNP - Small fiber neuropathy (709489006)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0800207" target="_blank">MONDO:0800207</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/133020" target="_blank">133020</a>; <a href="https://omim.org/entry/603415" target="_blank">603415</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Small fiber neuropathy is a condition characterized by severe pain attacks that typically begin in the feet or hands. As a person ages, the pain attacks can affect other regions. Some people initially experience a more generalized, whole-body pain. The attacks usually consist of pain described as stabbing or burning, or abnormal skin sensations such as tingling or itchiness. In some individuals, the pain is more severe during times of rest or at night. The signs and symptoms of small fiber neuropathy usually begin in adolescence to mid-adulthood.<br /><br />Individuals with small fiber neuropathy cannot feel pain that is concentrated in a very small area, such as the prick of a pin. However, they have an increased sensitivity to pain in general (hyperalgesia) and experience pain from stimulation that typically does not cause pain (allodynia). People affected with this condition may also have a reduced ability to differentiate between hot and cold. However, in some individuals, the pain attacks are provoked by cold or warm triggers.<br /><br />Some affected individuals have urinary or bowel problems, episodes of rapid heartbeat (palpitations), dry eyes or mouth, or abnormal sweating. They can also experience a sharp drop in blood pressure upon standing (orthostatic hypotension), which can cause dizziness, blurred vision, or fainting.<br /><br />Small fiber neuropathy is considered a form of peripheral neuropathy because it affects the peripheral nervous system, which connects the brain and spinal cord to muscles and to cells that detect sensations such as touch, smell, and pain. [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C3276706[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=478336">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=478336" target="_blank" href="/omim/133020">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=478336" ref="ncbi_uid=478336">V</a></span></span><span class="TLline">Small fiber neuropathy</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/14336" ref="tree=MeSH" title="MedGen record for Disorder of nervous system">Disorder of nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/141046" ref="tree=MeSH" title="MedGen record for Neuropathy">Neuropathy</a></span><ul><li><span class="matched_ds">Small fiber neuropathy</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38353900">Mast Cell Activation Syndrome and Gut Dysfunction: Diagnosis and Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hamilton MJ</span><br />
<span class="medgenPMjournal">Curr Gastroenterol Rep</span>
2024 Apr;26(4):107-114.
Epub 2024 Feb 14
doi: 10.1007/s11894-024-00924-w.
<span class="bold">PMID: </span><a href="/pubmed/38353900" target="_blank">38353900</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37432872">Updated consensus statement: Intravenous immunoglobulin in the treatment of neuromuscular disorders report of the AANEM ad hoc committee.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tavee J,
Brannagan TH 3rd,
Lenihan MW,
Muppidi S,
Kellermeyer L,
D Donofrio P;
AANEM</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2023 Oct;68(4):356-374.
Epub 2023 Jul 11
doi: 10.1002/mus.27922.
<span class="bold">PMID: </span><a href="/pubmed/37432872" target="_blank">37432872</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32654574">Clinical diagnosis and management of small fiber neuropathy: an update on best practice.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devigili G,
Cazzato D,
Lauria G</span><br />
<span class="medgenPMjournal">Expert Rev Neurother</span>
2020 Sep;20(9):967-980.
Epub 2020 Jul 23
doi: 10.1080/14737175.2020.1794825.
<span class="bold">PMID: </span><a href="/pubmed/32654574" target="_blank">32654574</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22small%20fiber%20neuropathy%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (47)</a></div></div>
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<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36086910">Primary Sjögren syndrome-related peripheral neuropathy: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liampas A,
Parperis K,
Erotocritou MF,
Nteveros A,
Papadopoulou M,
Moschovos C,
Akil M,
Coaccioli S,
Hadjigeorgiou GM,
Hadjivassiliou M,
Zis P</span><br />
<span class="medgenPMjournal">Eur J Neurol</span>
2023 Jan;30(1):255-265.
Epub 2022 Sep 23
doi: 10.1111/ene.15555.
<span class="bold">PMID: </span><a href="/pubmed/36086910" target="_blank">36086910</a><a href="/pmc/articles/PMC10087501" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33098165">Metabolic syndrome and peripheral neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kazamel M,
Stino AM,
Smith AG</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Mar;63(3):285-293.
Epub 2020 Oct 24
doi: 10.1002/mus.27086.
<span class="bold">PMID: </span><a href="/pubmed/33098165" target="_blank">33098165</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32654574">Clinical diagnosis and management of small fiber neuropathy: an update on best practice.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devigili G,
Cazzato D,
Lauria G</span><br />
<span class="medgenPMjournal">Expert Rev Neurother</span>
2020 Sep;20(9):967-980.
Epub 2020 Jul 23
doi: 10.1080/14737175.2020.1794825.
<span class="bold">PMID: </span><a href="/pubmed/32654574" target="_blank">32654574</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31639835">A Clinician's Approach to Peripheral Neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Siao P,
Kaku M</span><br />
<span class="medgenPMjournal">Semin Neurol</span>
2019 Oct;39(5):519-530.
Epub 2019 Oct 22
doi: 10.1055/s-0039-1694747.
<span class="bold">PMID: </span><a href="/pubmed/31639835" target="_blank">31639835</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29029847">The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Terkelsen AJ,
Karlsson P,
Lauria G,
Freeman R,
Finnerup NB,
Jensen TS</span><br />
<span class="medgenPMjournal">Lancet Neurol</span>
2017 Nov;16(11):934-944.
doi: 10.1016/S1474-4422(17)30329-0.
<span class="bold">PMID: </span><a href="/pubmed/29029847" target="_blank">29029847</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (361)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35384587">Small Fiber Neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Strand N,
Wie C,
Peck J,
Maita M,
Singh N,
Dumbroff J,
Tieppo Francio V,
Murphy M,
Chang K,
Dickerson DM,
Maloney J</span><br />
<span class="medgenPMjournal">Curr Pain Headache Rep</span>
2022 Jun;26(6):429-438.
Epub 2022 Apr 6
doi: 10.1007/s11916-022-01044-8.
<span class="bold">PMID: </span><a href="/pubmed/35384587" target="_blank">35384587</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35130356">Small fiber neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Finsterer J,
Scorza FA</span><br />
<span class="medgenPMjournal">Acta Neurol Scand</span>
2022 May;145(5):493-503.
Epub 2022 Feb 7
doi: 10.1111/ane.13591.
<span class="bold">PMID: </span><a href="/pubmed/35130356" target="_blank">35130356</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33098165">Metabolic syndrome and peripheral neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kazamel M,
Stino AM,
Smith AG</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Mar;63(3):285-293.
Epub 2020 Oct 24
doi: 10.1002/mus.27086.
<span class="bold">PMID: </span><a href="/pubmed/33098165" target="_blank">33098165</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32654574">Clinical diagnosis and management of small fiber neuropathy: an update on best practice.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Devigili G,
Cazzato D,
Lauria G</span><br />
<span class="medgenPMjournal">Expert Rev Neurother</span>
2020 Sep;20(9):967-980.
Epub 2020 Jul 23
doi: 10.1080/14737175.2020.1794825.
<span class="bold">PMID: </span><a href="/pubmed/32654574" target="_blank">32654574</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31639840">Small Fiber Neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou L</span><br />
<span class="medgenPMjournal">Semin Neurol</span>
2019 Oct;39(5):570-577.
Epub 2019 Oct 22
doi: 10.1055/s-0039-1688977.
<span class="bold">PMID: </span><a href="/pubmed/31639840" target="_blank">31639840</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (582)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36738954">Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) in 2023.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cohen Tervaert JW,
Martinez-Lavin M,
Jara LJ,
Halpert G,
Watad A,
Amital H,
Shoenfeld Y</span><br />
<span class="medgenPMjournal">Autoimmun Rev</span>
2023 May;22(5):103287.
Epub 2023 Feb 3
doi: 10.1016/j.autrev.2023.103287.
<span class="bold">PMID: </span><a href="/pubmed/36738954" target="_blank">36738954</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35384587">Small Fiber Neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Strand N,
Wie C,
Peck J,
Maita M,
Singh N,
Dumbroff J,
Tieppo Francio V,
Murphy M,
Chang K,
Dickerson DM,
Maloney J</span><br />
<span class="medgenPMjournal">Curr Pain Headache Rep</span>
2022 Jun;26(6):429-438.
Epub 2022 Apr 6
doi: 10.1007/s11916-022-01044-8.
<span class="bold">PMID: </span><a href="/pubmed/35384587" target="_blank">35384587</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35130356">Small fiber neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Finsterer J,
Scorza FA</span><br />
<span class="medgenPMjournal">Acta Neurol Scand</span>
2022 May;145(5):493-503.
Epub 2022 Feb 7
doi: 10.1111/ane.13591.
<span class="bold">PMID: </span><a href="/pubmed/35130356" target="_blank">35130356</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33098165">Metabolic syndrome and peripheral neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kazamel M,
Stino AM,
Smith AG</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Mar;63(3):285-293.
Epub 2020 Oct 24
doi: 10.1002/mus.27086.
<span class="bold">PMID: </span><a href="/pubmed/33098165" target="_blank">33098165</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30569495">Small-fiber neuropathy: Expanding the clinical pain universe.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sopacua M,
Hoeijmakers JGJ,
Merkies ISJ,
Lauria G,
Waxman SG,
Faber CG</span><br />
<span class="medgenPMjournal">J Peripher Nerv Syst</span>
2019 Mar;24(1):19-33.
Epub 2019 Jan 8
doi: 10.1111/jns.12298.
<span class="bold">PMID: </span><a href="/pubmed/30569495" target="_blank">30569495</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (182)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36448457">Expanding the genetic causes of small-fiber neuropathy: SCN genes and beyond.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chan ACY,
Kumar S,
Tan G,
Wong HY,
Ong JJY,
Chandra B,
Huang H,
Sharma VK,
Lai PS</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2023 Apr;67(4):259-271.
Epub 2022 Nov 30
doi: 10.1002/mus.27752.
<span class="bold">PMID: </span><a href="/pubmed/36448457" target="_blank">36448457</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36086910">Primary Sjögren syndrome-related peripheral neuropathy: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liampas A,
Parperis K,
Erotocritou MF,
Nteveros A,
Papadopoulou M,
Moschovos C,
Akil M,
Coaccioli S,
Hadjigeorgiou GM,
Hadjivassiliou M,
Zis P</span><br />
<span class="medgenPMjournal">Eur J Neurol</span>
2023 Jan;30(1):255-265.
Epub 2022 Sep 23
doi: 10.1111/ene.15555.
<span class="bold">PMID: </span><a href="/pubmed/36086910" target="_blank">36086910</a><a href="/pmc/articles/PMC10087501" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35772032">State-of-the-Art Treatments for Sarcoidosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Papanikolaou IC,
Antonakis E,
Pandi A</span><br />
<span class="medgenPMjournal">Methodist Debakey Cardiovasc J</span>
2022;18(2):94-105.
Epub 2022 Mar 14
doi: 10.14797/mdcvj.1068.
<span class="bold">PMID: </span><a href="/pubmed/35772032" target="_blank">35772032</a><a href="/pmc/articles/PMC9237819" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33098165">Metabolic syndrome and peripheral neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kazamel M,
Stino AM,
Smith AG</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Mar;63(3):285-293.
Epub 2020 Oct 24
doi: 10.1002/mus.27086.
<span class="bold">PMID: </span><a href="/pubmed/33098165" target="_blank">33098165</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31639840">Small Fiber Neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou L</span><br />
<span class="medgenPMjournal">Semin Neurol</span>
2019 Oct;39(5):570-577.
Epub 2019 Oct 22
doi: 10.1055/s-0039-1688977.
<span class="bold">PMID: </span><a href="/pubmed/31639840" target="_blank">31639840</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (138)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/34639176">Inflammatory Mechanisms in the Pathophysiology of Diabetic Peripheral Neuropathy (DN)-New Aspects.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baum P,
Toyka KV,
Blüher M,
Kosacka J,
Nowicki M</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2021 Oct 7;22(19)
doi: 10.3390/ijms221910835.
<span class="bold">PMID: </span><a href="/pubmed/34639176" target="_blank">34639176</a><a href="/pmc/articles/PMC8509236" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33551341">Sudomotor dysfunction in patients recovered from COVID-19.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hinduja A,
Moutairou A,
Calvet JH</span><br />
<span class="medgenPMjournal">Neurophysiol Clin</span>
2021 Mar;51(2):193-196.
Epub 2021 Jan 26
doi: 10.1016/j.neucli.2021.01.003.
<span class="bold">PMID: </span><a href="/pubmed/33551341" target="_blank">33551341</a><a href="/pmc/articles/PMC7835104" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33419664">Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cheshire WP,
Freeman R,
Gibbons CH,
Cortelli P,
Wenning GK,
Hilz MJ,
Spies JM,
Lipp A,
Sandroni P,
Wada N,
Mano A,
Ah Kim H,
Kimpinski K,
Iodice V,
Idiáquez J,
Thaisetthawatkul P,
Coon EA,
Low PA,
Singer W</span><br />
<span class="medgenPMjournal">Clin Neurophysiol</span>
2021 Feb;132(2):666-682.
Epub 2020 Dec 22
doi: 10.1016/j.clinph.2020.11.024.
<span class="bold">PMID: </span><a href="/pubmed/33419664" target="_blank">33419664</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33098165">Metabolic syndrome and peripheral neuropathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kazamel M,
Stino AM,
Smith AG</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Mar;63(3):285-293.
Epub 2020 Oct 24
doi: 10.1002/mus.27086.
<span class="bold">PMID: </span><a href="/pubmed/33098165" target="_blank">33098165</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31365388">Nonorgan manifestations of sarcoidosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tavee J,
Culver D</span><br />
<span class="medgenPMjournal">Curr Opin Pulm Med</span>
2019 Sep;25(5):533-538.
doi: 10.1097/MCP.0000000000000597.
<span class="bold">PMID: </span><a href="/pubmed/31365388" target="_blank">31365388</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (251)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/39518993">Small Fiber Neuropathy in Burning Mouth Syndrome: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kouri M,
Adamo D,
Vardas E,
Georgaki M,
Canfora F,
Mignogna MD,
Nikitakis N</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2024 Oct 24;25(21)
doi: 10.3390/ijms252111442.
<span class="bold">PMID: </span><a href="/pubmed/39518993" target="_blank">39518993</a><a href="/pmc/articles/PMC11546372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36448457">Expanding the genetic causes of small-fiber neuropathy: SCN genes and beyond.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chan ACY,
Kumar S,
Tan G,
Wong HY,
Ong JJY,
Chandra B,
Huang H,
Sharma VK,
Lai PS</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2023 Apr;67(4):259-271.
Epub 2022 Nov 30
doi: 10.1002/mus.27752.
<span class="bold">PMID: </span><a href="/pubmed/36448457" target="_blank">36448457</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36086910">Primary Sjögren syndrome-related peripheral neuropathy: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liampas A,
Parperis K,
Erotocritou MF,
Nteveros A,
Papadopoulou M,
Moschovos C,
Akil M,
Coaccioli S,
Hadjigeorgiou GM,
Hadjivassiliou M,
Zis P</span><br />
<span class="medgenPMjournal">Eur J Neurol</span>
2023 Jan;30(1):255-265.
Epub 2022 Sep 23
doi: 10.1111/ene.15555.
<span class="bold">PMID: </span><a href="/pubmed/36086910" target="_blank">36086910</a><a href="/pmc/articles/PMC10087501" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32989823">Diagnostic criteria for idiopathic small fiber neuropathy: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Haroutounian S,
Todorovic MS,
Leinders M,
Campagnolo M,
Gewandter JS,
Dworkin RH,
Freeman R</span><br />
<span class="medgenPMjournal">Muscle Nerve</span>
2021 Feb;63(2):170-177.
Epub 2020 Sep 29
doi: 10.1002/mus.27070.
<span class="bold">PMID: </span><a href="/pubmed/32989823" target="_blank">32989823</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30295933">Hereditary transthyretin-related amyloidosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Finsterer J,
Iglseder S,
Wanschitz J,
Topakian R,
Löscher WN,
Grisold W</span><br />
<span class="medgenPMjournal">Acta Neurol Scand</span>
2019 Feb;139(2):92-105.
Epub 2018 Oct 23
doi: 10.1111/ane.13035.
<span class="bold">PMID: </span><a href="/pubmed/30295933" target="_blank">30295933</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Small%20fiber%20neuropathy%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C3276706%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (2)</a></li>
<li><a href="/gtr/tests?term=C3276706%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (3)</a></li>
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C3276706%5bDISCUI%5d" target="_blank">See all (3)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Small%20fiber%20neuropathy" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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