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<meta name="keywords" content="C2931822, cancer of nasopharynx, cancer of the nasopharynx, carcinoma of nasopharynx, carcinoma of the nasopharynx, carcinoma, nasopharyngeal, carcinomas, nasopharyngeal, nasopharyngeal cancer, nasopharyngeal carcinoma, nasopharyngeal carcinoma, somatic, nasopharyngeal carcinomas, nasopharynx carcinoma, neoplastic process, npc, npca, squamous cell carcinoma of the nasopharynx, tp53, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated (Tse et al., 2009). Genetic Heterogeneity of Susceptibility to Nasopharyngeal Carcinoma NPCA1 maps to chromosome 4p. NPCA2 (161550) maps to chromosome 6p21. NPCA3 (617075) is associated with variation in the MST1R gene (600168) on chromosome 3p21. Somatic mutations have been found in the TP53 gene (191170) in nasopharyngeal carcinoma tumors." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=419909
|
||
ConceptID=C2931822
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Nasopharyngeal carcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>419909</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C2931822</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Nasopharyngeal carcinoma, somatic</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Nasopharyngeal carcinoma (449248000)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_109109"><div><strong>Non-Mendelian inheritance</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>109109</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0600599</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Genetic Function</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">A mode of inheritance that depends on genetic determinants in more than one gene.</div></div>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_109109" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Non-Mendelian inheritance</a><span> (Orphanet)</span></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Gene (location):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="TP53 - ID: 7157 - NCBI Gene" href="/gene/7157" class="medgenPMinfo">TP53</a> (17p13.1)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0015459" target="_blank">MONDO:0015459</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/607107" target="_blank">607107</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=150">ORPHA150</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated (Tse et al., 2009). Genetic Heterogeneity of Susceptibility to Nasopharyngeal Carcinoma NPCA1 maps to chromosome 4p. NPCA2 (161550) maps to chromosome 6p21. NPCA3 (617075) is associated with variation in the MST1R gene (600168) on chromosome 3p21. Somatic mutations have been found in the TP53 gene (191170) in nasopharyngeal carcinoma tumors. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_6526"><div><strong>Nasopharyngeal neoplasm</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6526</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027439</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A benign or malignant neoplasm affecting the nasopharynx. Representative examples of benign neoplasms include angiofibroma and squamous papilloma. Representative examples of malignant neoplasms include keratinizing squamous cell carcinoma and nonkeratinizing carcinoma.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6526">Feature record</a> | <a href="/medgen?term=%22Nasopharyngeal%20neoplasm%22%5BClinical%20Features%5D%20OR%206526%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_6526" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nasopharyngeal neoplasm</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2931822[DISCUI]&test_type=Clinical" ref="ncbi_uid=419909">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=419909" target="_blank" href="/omim/607107">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=419909" ref="ncbi_uid=419909">V</a></span></span><span class="TLline">Nasopharyngeal carcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="matched_ds">Nasopharyngeal carcinoma</span><ul><li><span class="TLline"><a href="/medgen/235127" ref="tree=MeSH" title="MedGen record for Metastatic Nasopharyngeal Carcinoma">Metastatic Nasopharyngeal Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1778755" ref="tree=MeSH" title="MedGen record for Advanced Nasopharyngeal Carcinoma">Advanced Nasopharyngeal Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1662916" ref="tree=MeSH" title="MedGen record for Advanced Nasopharyngeal Squamous Cell Carcinoma">Advanced Nasopharyngeal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1653175" ref="tree=MeSH" title="MedGen record for Metastatic Nasopharyngeal Squamous Cell Carcinoma">Metastatic Nasopharyngeal Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1712139" ref="tree=MeSH" title="MedGen record for Locally Advanced Nasopharyngeal Squamous Cell Carcinoma">Locally Advanced Nasopharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1663213" ref="tree=MeSH" title="MedGen record for Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma">Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1780642" ref="tree=MeSH" title="MedGen record for Metastatic Nasopharyngeal Non-Keratinizing Carcinoma">Metastatic Nasopharyngeal Non-Keratinizing Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1736996" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Adenoid Cystic Carcinoma">Nasopharyngeal Adenoid Cystic Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/455946" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Carcinoma by AJCC v6 Stage">Nasopharyngeal Carcinoma by AJCC v6 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1613416" ref="tree=MeSH" title="MedGen record for Stage 0 Nasopharyngeal Carcinoma AJCC v6, v7, and v8">Stage 0 Nasopharyngeal Carcinoma AJCC v6, v7, and v8</a></span><ul><li><span class="TLline"><a href="/medgen/1621368" ref="tree=MeSH" title="MedGen record for Stage 0 Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v6, v7, and v8">Stage 0 Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v6, v7, and v8</a></span></li><li><span class="TLline"><a href="/medgen/1612588" ref="tree=MeSH" title="MedGen record for Stage 0 Nasopharyngeal Undifferentiated Carcinoma AJCC v6, v7, and v8">Stage 0 Nasopharyngeal Undifferentiated Carcinoma AJCC v6, v7, and v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235125" ref="tree=MeSH" title="MedGen record for Stage I Nasopharyngeal Carcinoma AJCC v6">Stage I Nasopharyngeal Carcinoma AJCC v6</a></span></li><li><span class="TLline"><a href="/medgen/1616020" ref="tree=MeSH" title="MedGen record for Stage II Nasopharyngeal Carcinoma AJCC v6">Stage II Nasopharyngeal Carcinoma AJCC v6</a></span></li><li><span class="TLline"><a href="/medgen/235126" ref="tree=MeSH" title="MedGen record for Stage III Nasopharyngeal Carcinoma AJCC v6">Stage III Nasopharyngeal Carcinoma AJCC v6</a></span></li><li><span class="TLline"><a href="/medgen/1624505" ref="tree=MeSH" title="MedGen record for Stage IV Nasopharyngeal Carcinoma AJCC v6">Stage IV Nasopharyngeal Carcinoma AJCC v6</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/456335" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Carcinoma by AJCC v7 Stage">Nasopharyngeal Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1638589" ref="tree=MeSH" title="MedGen record for Stage I Nasopharyngeal Carcinoma AJCC v7">Stage I Nasopharyngeal Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/79110" ref="tree=MeSH" title="MedGen record for Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7">Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/83641" ref="tree=MeSH" title="MedGen record for Stage I Nasopharyngeal Undifferentiated Carcinoma AJCC v7">Stage I Nasopharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/454664" ref="tree=MeSH" title="MedGen record for Stage II Nasopharyngeal Carcinoma AJCC v7">Stage II Nasopharyngeal Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/124733" ref="tree=MeSH" title="MedGen record for Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7">Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/83642" ref="tree=MeSH" title="MedGen record for Stage II Nasopharyngeal Undifferentiated Carcinoma AJCC v7">Stage II Nasopharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1617135" ref="tree=MeSH" title="MedGen record for Stage III Nasopharyngeal Carcinoma AJCC v7">Stage III Nasopharyngeal Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/83643" ref="tree=MeSH" title="MedGen record for Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7">Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/76104" ref="tree=MeSH" title="MedGen record for Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7">Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/459987" ref="tree=MeSH" title="MedGen record for Stage IV Nasopharyngeal Carcinoma AJCC v7">Stage IV Nasopharyngeal Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/1653060" ref="tree=MeSH" title="MedGen record for Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7">Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/124734" ref="tree=MeSH" title="MedGen record for Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7">Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/233517" ref="tree=MeSH" title="MedGen record for Stage IVA Nasopharyngeal Carcinoma AJCC v7">Stage IVA Nasopharyngeal Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/277741" ref="tree=MeSH" title="MedGen record for Stage IVB Nasopharyngeal Carcinoma AJCC v7">Stage IVB Nasopharyngeal Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/236932" ref="tree=MeSH" title="MedGen record for Stage IVC Nasopharyngeal Carcinoma AJCC v7">Stage IVC Nasopharyngeal Carcinoma AJCC v7</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1393839" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Carcinoma by AJCC v8 Stage">Nasopharyngeal Carcinoma by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1385283" ref="tree=MeSH" title="MedGen record for Stage I Nasopharyngeal Carcinoma AJCC v8">Stage I Nasopharyngeal Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1375519" ref="tree=MeSH" title="MedGen record for Stage II Nasopharyngeal Carcinoma AJCC v8">Stage II Nasopharyngeal Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1387420" ref="tree=MeSH" title="MedGen record for Stage III Nasopharyngeal Carcinoma AJCC v8">Stage III Nasopharyngeal Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1386732" ref="tree=MeSH" title="MedGen record for Stage IV Nasopharyngeal Carcinoma AJCC v8">Stage IV Nasopharyngeal Carcinoma AJCC v8</a></span><ul><li><span class="TLline"><a href="/medgen/1377877" ref="tree=MeSH" title="MedGen record for Stage IVA Nasopharyngeal Carcinoma AJCC v8">Stage IVA Nasopharyngeal Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1390826" ref="tree=MeSH" title="MedGen record for Stage IVB Nasopharyngeal Carcinoma AJCC v8">Stage IVB Nasopharyngeal Carcinoma AJCC v8</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/354457" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Low Grade Papillary Adenocarcinoma">Nasopharyngeal Low Grade Papillary Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/76017" ref="tree=MeSH" title="MedGen record for Nasopharyngeal squamous cell carcinoma">Nasopharyngeal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/328304" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Basaloid Squamous Cell Carcinoma">Nasopharyngeal Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1708895" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Keratinizing Squamous Cell Carcinoma">Nasopharyngeal Keratinizing Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1717441" ref="tree=MeSH" title="MedGen record for Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma">Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277408" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Non-Keratinizing Carcinoma">Nasopharyngeal Non-Keratinizing Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/313473" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Differentiated Carcinoma">Nasopharyngeal Differentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/124650" ref="tree=MeSH" title="MedGen record for Undifferentiated carcinoma of nasopharynx">Undifferentiated carcinoma of nasopharynx</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/76105" ref="tree=MeSH" title="MedGen record for Recurrent Nasopharyngeal Squamous Cell Carcinoma">Recurrent Nasopharyngeal Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/83645" ref="tree=MeSH" title="MedGen record for Recurrent Nasopharyngeal Undifferentiated Carcinoma">Recurrent Nasopharyngeal Undifferentiated Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1737201" ref="tree=MeSH" title="MedGen record for Unresectable Nasopharyngeal Squamous Cell Carcinoma">Unresectable Nasopharyngeal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83013" ref="tree=MeSH" title="MedGen record for Recurrent Nasopharyngeal Carcinoma">Recurrent Nasopharyngeal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1653446" ref="tree=MeSH" title="MedGen record for Refractory Nasopharyngeal Carcinoma">Refractory Nasopharyngeal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1715939" ref="tree=MeSH" title="MedGen record for Unresectable Nasopharyngeal Carcinoma">Unresectable Nasopharyngeal Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=1063&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Nasopharyngeal carcinoma</span> in Orphanet.</div></div></div>
|
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</div>
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|
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/37658764">International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kuan EC,
|
||
Wang EW,
|
||
Adappa ND,
|
||
Beswick DM,
|
||
London NR Jr,
|
||
Su SY,
|
||
Wang MB,
|
||
Abuzeid WM,
|
||
Alexiev B,
|
||
Alt JA,
|
||
Antognoni P,
|
||
Alonso-Basanta M,
|
||
Batra PS,
|
||
Bhayani M,
|
||
Bell D,
|
||
Bernal-Sprekelsen M,
|
||
Betz CS,
|
||
Blay JY,
|
||
Bleier BS,
|
||
Bonilla-Velez J,
|
||
Callejas C,
|
||
Carrau RL,
|
||
Casiano RR,
|
||
Castelnuovo P,
|
||
Chandra RK,
|
||
Chatzinakis V,
|
||
Chen SB,
|
||
Chiu AG,
|
||
Choby G,
|
||
Chowdhury NI,
|
||
Citardi MJ,
|
||
Cohen MA,
|
||
Dagan R,
|
||
Dalfino G,
|
||
Dallan I,
|
||
Dassi CS,
|
||
de Almeida J,
|
||
Dei Tos AP,
|
||
DelGaudio JM,
|
||
Ebert CS,
|
||
El-Sayed IH,
|
||
Eloy JA,
|
||
Evans JJ,
|
||
Fang CH,
|
||
Farrell NF,
|
||
Ferrari M,
|
||
Fischbein N,
|
||
Folbe A,
|
||
Fokkens WJ,
|
||
Fox MG,
|
||
Lund VJ,
|
||
Gallia GL,
|
||
Gardner PA,
|
||
Geltzeiler M,
|
||
Georgalas C,
|
||
Getz AE,
|
||
Govindaraj S,
|
||
Gray ST,
|
||
Grayson JW,
|
||
Gross BA,
|
||
Grube JG,
|
||
Guo R,
|
||
Ha PK,
|
||
Halderman AA,
|
||
Hanna EY,
|
||
Harvey RJ,
|
||
Hernandez SC,
|
||
Holtzman AL,
|
||
Hopkins C,
|
||
Huang Z,
|
||
Huang Z,
|
||
Humphreys IM,
|
||
Hwang PH,
|
||
Iloreta AM,
|
||
Ishii M,
|
||
Ivan ME,
|
||
Jafari A,
|
||
Kennedy DW,
|
||
Khan M,
|
||
Kimple AJ,
|
||
Kingdom TT,
|
||
Knisely A,
|
||
Kuo YJ,
|
||
Lal D,
|
||
Lamarre ED,
|
||
Lan MY,
|
||
Le H,
|
||
Lechner M,
|
||
Lee NY,
|
||
Lee JK,
|
||
Lee VH,
|
||
Levine CG,
|
||
Lin JC,
|
||
Lin DT,
|
||
Lobo BC,
|
||
Locke T,
|
||
Luong AU,
|
||
Magliocca KR,
|
||
Markovic SN,
|
||
Matnjani G,
|
||
McKean EL,
|
||
Meço C,
|
||
Mendenhall WM,
|
||
Michel L,
|
||
Na'ara S,
|
||
Nicolai P,
|
||
Nuss DW,
|
||
Nyquist GG,
|
||
Oakley GM,
|
||
Omura K,
|
||
Orlandi RR,
|
||
Otori N,
|
||
Papagiannopoulos P,
|
||
Patel ZM,
|
||
Pfister DG,
|
||
Phan J,
|
||
Psaltis AJ,
|
||
Rabinowitz MR,
|
||
Ramanathan M Jr,
|
||
Rimmer R,
|
||
Rosen MR,
|
||
Sanusi O,
|
||
Sargi ZB,
|
||
Schafhausen P,
|
||
Schlosser RJ,
|
||
Sedaghat AR,
|
||
Senior BA,
|
||
Shrivastava R,
|
||
Sindwani R,
|
||
Smith TL,
|
||
Smith KA,
|
||
Snyderman CH,
|
||
Solares CA,
|
||
Sreenath SB,
|
||
Stamm A,
|
||
Stölzel K,
|
||
Sumer B,
|
||
Surda P,
|
||
Tajudeen BA,
|
||
Thompson LDR,
|
||
Thorp BD,
|
||
Tong CCL,
|
||
Tsang RK,
|
||
Turner JH,
|
||
Turri-Zanoni M,
|
||
Udager AM,
|
||
van Zele T,
|
||
VanKoevering K,
|
||
Welch KC,
|
||
Wise SK,
|
||
Witterick IJ,
|
||
Won TB,
|
||
Wong SN,
|
||
Woodworth BA,
|
||
Wormald PJ,
|
||
Yao WC,
|
||
Yeh CF,
|
||
Zhou B,
|
||
Palmer JN</span><br />
|
||
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
|
||
2024 Feb;14(2):149-608.
|
||
Epub 2024 Jan 2
|
||
doi: 10.1002/alr.23262.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37658764" target="_blank">37658764</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33358989">Nasopharyngeal carcinoma: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up(†).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bossi P,
|
||
Chan AT,
|
||
Licitra L,
|
||
Trama A,
|
||
Orlandi E,
|
||
Hui EP,
|
||
Halámková J,
|
||
Mattheis S,
|
||
Baujat B,
|
||
Hardillo J,
|
||
Smeele L,
|
||
van Herpen C,
|
||
Castro A,
|
||
Machiels JP;
|
||
ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org;
|
||
EURACAN</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2021 Apr;32(4):452-465.
|
||
Epub 2020 Dec 25
|
||
doi: 10.1016/j.annonc.2020.12.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33358989" target="_blank">33358989</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31470314">Management of locally recurrent nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee AWM,
|
||
Ng WT,
|
||
Chan JYW,
|
||
Corry J,
|
||
Mäkitie A,
|
||
Mendenhall WM,
|
||
Rinaldo A,
|
||
Rodrigo JP,
|
||
Saba NF,
|
||
Strojan P,
|
||
Suárez C,
|
||
Vermorken JB,
|
||
Yom SS,
|
||
Ferlito A</span><br />
|
||
<span class="medgenPMjournal">Cancer Treat Rev</span>
|
||
2019 Sep;79:101890.
|
||
Epub 2019 Aug 21
|
||
doi: 10.1016/j.ctrv.2019.101890.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31470314" target="_blank">31470314</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22nasopharyngeal%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (711)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38430391">Epidemiology of nasopharyngeal carcinoma: current insights and future outlook.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Su ZY,
|
||
Siak PY,
|
||
Lwin YY,
|
||
Cheah SC</span><br />
|
||
<span class="medgenPMjournal">Cancer Metastasis Rev</span>
|
||
2024 Sep;43(3):919-939.
|
||
Epub 2024 Mar 2
|
||
doi: 10.1007/s10555-024-10176-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38430391" target="_blank">38430391</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37097799">Radiomics and Deep Learning in Nasopharyngeal Carcinoma: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Z,
|
||
Fang M,
|
||
Zhang J,
|
||
Tang L,
|
||
Zhong L,
|
||
Li H,
|
||
Cao R,
|
||
Zhao X,
|
||
Liu S,
|
||
Zhang R,
|
||
Xie X,
|
||
Mai H,
|
||
Qiu S,
|
||
Tian J,
|
||
Dong D</span><br />
|
||
<span class="medgenPMjournal">IEEE Rev Biomed Eng</span>
|
||
2024;17:118-135.
|
||
Epub 2024 Jan 12
|
||
doi: 10.1109/RBME.2023.3269776.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37097799" target="_blank">37097799</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34089384">Optimal management of oligometastatic nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu H,
|
||
Yang P,
|
||
Jia Y</span><br />
|
||
<span class="medgenPMjournal">Eur Arch Otorhinolaryngol</span>
|
||
2022 Feb;279(2):567-576.
|
||
Epub 2021 Jun 5
|
||
doi: 10.1007/s00405-021-06918-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34089384" target="_blank">34089384</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31470314">Management of locally recurrent nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee AWM,
|
||
Ng WT,
|
||
Chan JYW,
|
||
Corry J,
|
||
Mäkitie A,
|
||
Mendenhall WM,
|
||
Rinaldo A,
|
||
Rodrigo JP,
|
||
Saba NF,
|
||
Strojan P,
|
||
Suárez C,
|
||
Vermorken JB,
|
||
Yom SS,
|
||
Ferlito A</span><br />
|
||
<span class="medgenPMjournal">Cancer Treat Rev</span>
|
||
2019 Sep;79:101890.
|
||
Epub 2019 Aug 21
|
||
doi: 10.1016/j.ctrv.2019.101890.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31470314" target="_blank">31470314</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31178151">Nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen YP,
|
||
Chan ATC,
|
||
Le QT,
|
||
Blanchard P,
|
||
Sun Y,
|
||
Ma J</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2019 Jul 6;394(10192):64-80.
|
||
Epub 2019 Jun 6
|
||
doi: 10.1016/S0140-6736(19)30956-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31178151" target="_blank">31178151</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5823)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37417358">Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang H,
|
||
Yao Y,
|
||
Deng X,
|
||
Huang Z,
|
||
Chen Y,
|
||
Wang Z,
|
||
Hong H,
|
||
Huang H,
|
||
Lin T</span><br />
|
||
<span class="medgenPMjournal">Int J Oncol</span>
|
||
2023 Aug;63(2)
|
||
Epub 2023 Jul 7
|
||
doi: 10.3892/ijo.2023.5545.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37417358" target="_blank">37417358</a><a href="/pmc/articles/PMC10367053" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33358989">Nasopharyngeal carcinoma: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up(†).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bossi P,
|
||
Chan AT,
|
||
Licitra L,
|
||
Trama A,
|
||
Orlandi E,
|
||
Hui EP,
|
||
Halámková J,
|
||
Mattheis S,
|
||
Baujat B,
|
||
Hardillo J,
|
||
Smeele L,
|
||
van Herpen C,
|
||
Castro A,
|
||
Machiels JP;
|
||
ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org;
|
||
EURACAN</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2021 Apr;32(4):452-465.
|
||
Epub 2020 Dec 25
|
||
doi: 10.1016/j.annonc.2020.12.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33358989" target="_blank">33358989</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32858472">Chemotherapy and chemo-resistance in nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Guan S,
|
||
Wei J,
|
||
Huang L,
|
||
Wu L</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Chem</span>
|
||
2020 Dec 1;207:112758.
|
||
Epub 2020 Aug 20
|
||
doi: 10.1016/j.ejmech.2020.112758.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32858472" target="_blank">32858472</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31178151">Nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen YP,
|
||
Chan ATC,
|
||
Le QT,
|
||
Blanchard P,
|
||
Sun Y,
|
||
Ma J</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2019 Jul 6;394(10192):64-80.
|
||
Epub 2019 Jun 6
|
||
doi: 10.1016/S0140-6736(19)30956-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31178151" target="_blank">31178151</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26321262">Nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chua MLK,
|
||
Wee JTS,
|
||
Hui EP,
|
||
Chan ATC</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2016 Mar 5;387(10022):1012-1024.
|
||
Epub 2015 Aug 28
|
||
doi: 10.1016/S0140-6736(15)00055-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26321262" target="_blank">26321262</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4377)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38015220">Toripalimab Plus Chemotherapy for Recurrent or Metastatic Nasopharyngeal Carcinoma: The JUPITER-02 Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mai HQ,
|
||
Chen QY,
|
||
Chen D,
|
||
Hu C,
|
||
Yang K,
|
||
Wen J,
|
||
Li J,
|
||
Shi Y,
|
||
Jin F,
|
||
Xu R,
|
||
Pan J,
|
||
Qu S,
|
||
Li P,
|
||
Hu C,
|
||
Liu YC,
|
||
Jiang Y,
|
||
He X,
|
||
Wang HM,
|
||
Lim WT,
|
||
Liao W,
|
||
He X,
|
||
Chen X,
|
||
Wang S,
|
||
Yuan X,
|
||
Li Q,
|
||
Lin X,
|
||
Jing S,
|
||
Chen Y,
|
||
Lu Y,
|
||
Hsieh CY,
|
||
Yang MH,
|
||
Yen CJ,
|
||
Samol J,
|
||
Luo X,
|
||
Wang X,
|
||
Tang X,
|
||
Feng H,
|
||
Yao S,
|
||
Keegan P,
|
||
Xu RH</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2023 Nov 28;330(20):1961-1970.
|
||
doi: 10.1001/jama.2023.20181.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38015220" target="_blank">38015220</a><a href="/pmc/articles/PMC10685882" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37417358">Immunotherapy for nasopharyngeal carcinoma: Current status and prospects (Review).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang H,
|
||
Yao Y,
|
||
Deng X,
|
||
Huang Z,
|
||
Chen Y,
|
||
Wang Z,
|
||
Hong H,
|
||
Huang H,
|
||
Lin T</span><br />
|
||
<span class="medgenPMjournal">Int J Oncol</span>
|
||
2023 Aug;63(2)
|
||
Epub 2023 Jul 7
|
||
doi: 10.3892/ijo.2023.5545.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37417358" target="_blank">37417358</a><a href="/pmc/articles/PMC10367053" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31150573">Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang Y,
|
||
Chen L,
|
||
Hu GQ,
|
||
Zhang N,
|
||
Zhu XD,
|
||
Yang KY,
|
||
Jin F,
|
||
Shi M,
|
||
Chen YP,
|
||
Hu WH,
|
||
Cheng ZB,
|
||
Wang SY,
|
||
Tian Y,
|
||
Wang XC,
|
||
Sun Y,
|
||
Li JG,
|
||
Li WF,
|
||
Li YH,
|
||
Tang LL,
|
||
Mao YP,
|
||
Zhou GQ,
|
||
Sun R,
|
||
Liu X,
|
||
Guo R,
|
||
Long GX,
|
||
Liang SQ,
|
||
Li L,
|
||
Huang J,
|
||
Long JH,
|
||
Zang J,
|
||
Liu QD,
|
||
Zou L,
|
||
Su QF,
|
||
Zheng BM,
|
||
Xiao Y,
|
||
Guo Y,
|
||
Han F,
|
||
Mo HY,
|
||
Lv JW,
|
||
Du XJ,
|
||
Xu C,
|
||
Liu N,
|
||
Li YQ,
|
||
Chua MLK,
|
||
Xie FY,
|
||
Sun Y,
|
||
Ma J</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2019 Sep 19;381(12):1124-1135.
|
||
Epub 2019 May 31
|
||
doi: 10.1056/NEJMoa1905287.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31150573" target="_blank">31150573</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29189159">Oncorine, the World First Oncolytic Virus Medicine and its Update in China.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liang M</span><br />
|
||
<span class="medgenPMjournal">Curr Cancer Drug Targets</span>
|
||
2018;18(2):171-176.
|
||
doi: 10.2174/1568009618666171129221503.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29189159" target="_blank">29189159</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12176778">Nasopharyngeal carcinoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chan AT,
|
||
Teo PM,
|
||
Johnson PJ</span><br />
|
||
<span class="medgenPMjournal">Ann Oncol</span>
|
||
2002 Jul;13(7):1007-15.
|
||
doi: 10.1093/annonc/mdf179.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12176778" target="_blank">12176778</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3373)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38878356">Global burdens of nasopharyngeal carcinoma in children and young adults and predictions to 2040.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lei S,
|
||
Chen L,
|
||
Ji P,
|
||
Li K,
|
||
Li Q,
|
||
Huang C,
|
||
Wang G,
|
||
Ma J,
|
||
Guo R,
|
||
Tang L</span><br />
|
||
<span class="medgenPMjournal">Oral Oncol</span>
|
||
2024 Aug;155:106891.
|
||
Epub 2024 Jun 14
|
||
doi: 10.1016/j.oraloncology.2024.106891.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38878356" target="_blank">38878356</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38430391">Epidemiology of nasopharyngeal carcinoma: current insights and future outlook.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Su ZY,
|
||
Siak PY,
|
||
Lwin YY,
|
||
Cheah SC</span><br />
|
||
<span class="medgenPMjournal">Cancer Metastasis Rev</span>
|
||
2024 Sep;43(3):919-939.
|
||
Epub 2024 Mar 2
|
||
doi: 10.1007/s10555-024-10176-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38430391" target="_blank">38430391</a></div>
|
||
|
||
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5371)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37269842">Role of chemotherapy in patients with nasopharynx carcinoma treated with radiotherapy (MAC-NPC): an updated individual patient data network meta-analysis.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29428165">Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study.</a></div>
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Li YQ,
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Jiang W,
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Mao YP,
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Yang XJ,
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<div class="nl"><a target="_blank" href="/pubmed/17921082">Tumour volume measurement in head and neck cancer.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4363)</a></div></div>
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</div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/38820656">A systematic review of antibody-drug conjugates and bispecific antibodies in head and neck squamous cell carcinoma and nasopharyngeal carcinoma: Charting the course of future therapies.</a></div>
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Rullan A,
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Hernando-Calvo A,
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Llop S,
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<span class="bold">PMID: </span><a href="/pubmed/38820656" target="_blank">38820656</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/33405943">Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chen YP,
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Ismaila N,
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<div class="nl"><a target="_blank" href="/pubmed/33202328">Viral markers in nasopharyngeal carcinoma: A systematic review and meta-analysis on the detection of p16(INK4a), human papillomavirus (HPV), and Ebstein-Barr virus (EBV).</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tham T,
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Machado R,
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<span class="bold">PMID: </span><a href="/pubmed/33202328" target="_blank">33202328</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31826376">Citrus fruit intake and the risk of nasopharyngeal carcinoma.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Feng XX,
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Wang MX,
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Li M,
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Tang X,
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Ma L,
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<div class="nl"><a target="_blank" href="/pubmed/31276776">International Guideline on Dose Prioritization and Acceptance Criteria in Radiation Therapy Planning for Nasopharyngeal Carcinoma.</a></div>
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Lee NY,
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Mendenhall WM,
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Peters LJ,
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Sanguineti G,
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<span class="bold">PMID: </span><a href="/pubmed/31276776" target="_blank">31276776</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nasopharyngeal%20carcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (152)</a></div></div>
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||
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|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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<div>
|
||
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C2931822%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (34)</a></li>
|
||
<li><a href="/gtr/tests?term=C2931822%5bDISCUI%5d&filter=method%3A2%5F30" target="_blank">RNA analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C2931822%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (9)</a></li>
|
||
<li><a href="/gtr/tests?term=C2931822%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (24)</a></li>
|
||
<li><a href="/gtr/tests?term=C2931822%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C2931822%5bDISCUI%5d" target="_blank">See all (48)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=607107" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=150" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Nasopharyngeal%20carcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22nasopharyngeal%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Nasopharyngeal%20carcinoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024</div></li></ul></div>
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