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<meta name="keywords" content="C1970243, autism 9, autism, susceptibility to, 9, auts9, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior (Bailey et al., 1996; Risch et al., 1999). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; 608638) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Mental retardation coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in which mental retardation is conspicuously absent (Jones et al., 2008). Genetic studies in autism often include family members with these less stringent diagnoses (Schellenberg et al., 2006).&#13; For a discussion of genetic heterogeneity of autism, see 209850." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=410023
ConceptID=C1970243
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Autism, susceptibility to, 9<span class="h1sub">(AUTS9)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>410023</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1970243</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Autism 9; AUTS9</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0012600" target="_blank">MONDO:0012600</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/611015" target="_blank">611015</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Autism, the prototypic pervasive developmental disorder (PDD), is usually apparent by 3 years of age. It is characterized by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypic, and ritualized patterns of interests and behavior (Bailey et al., 1996; Risch et al., 1999). 'Autism spectrum disorder,' sometimes referred to as ASD, is a broader phenotype encompassing the less severe disorders Asperger syndrome (see ASPG1; 608638) and pervasive developmental disorder, not otherwise specified (PDD-NOS). 'Broad autism phenotype' includes individuals with some symptoms of autism, but who do not meet the full criteria for autism or other disorders. Mental retardation coexists in approximately two-thirds of individuals with ASD, except for Asperger syndrome, in which mental retardation is conspicuously absent (Jones et al., 2008). Genetic studies in autism often include family members with these less stringent diagnoses (Schellenberg et al., 2006).&#13; For a discussion of genetic heterogeneity of autism, see 209850. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38568605">Susceptibility to Treatment-Resistant Depression Within Families.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cheng CM,
Chen MH,
Tsai SJ,
Chang WH,
Tsai CF,
Lin WC,
Bai YM,
Su TP,
Chen TJ,
Li CT</span><br />
<span class="medgenPMjournal">JAMA Psychiatry</span>
2024 Jul 1;81(7):663-672.
doi: 10.1001/jamapsychiatry.2024.0378.
<span class="bold">PMID: </span><a href="/pubmed/38568605" target="_blank">38568605</a><a href="/pmc/articles/PMC10993159" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32472753">Risk factors, diagnosis, prognosis and treatment of autism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Styles M,
Alsharshani D,
Samara M,
Alsharshani M,
Khattab A,
Qoronfleh MW,
Al-Dewik NI</span><br />
<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
2020 Jun 1;25(9):1682-1717.
doi: 10.2741/4873.
<span class="bold">PMID: </span><a href="/pubmed/32472753" target="_blank">32472753</a></div>
<div class="nl"><a target="_blank" href="/pubmed/14534514">Diagnosis and treatment of autism spectrum disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Manning-Courtney P,
Brown J,
Molloy CA,
Reinhold J,
Murray D,
Sorensen-Burnworth R,
Messerschmidt T,
Kent B</span><br />
<span class="medgenPMjournal">Curr Probl Pediatr Adolesc Health Care</span>
2003 Oct;33(9):283-304.
doi: 10.1016/s1538-5442(03)00108-1.
<span class="bold">PMID: </span><a href="/pubmed/14534514" target="_blank">14534514</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(autism%2C%20susceptibility%20to%2C%209)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (14)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36368308">Genomic architecture of autism from comprehensive whole-genome sequence annotation.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Trost B,
Thiruvahindrapuram B,
Chan AJS,
Engchuan W,
Higginbotham EJ,
Howe JL,
Loureiro LO,
Reuter MS,
Roshandel D,
Whitney J,
Zarrei M,
Bookman M,
Somerville C,
Shaath R,
Abdi M,
Aliyev E,
Patel RV,
Nalpathamkalam T,
Pellecchia G,
Hamdan O,
Kaur G,
Wang Z,
MacDonald JR,
Wei J,
Sung WWL,
Lamoureux S,
Hoang N,
Selvanayagam T,
Deflaux N,
Geng M,
Ghaffari S,
Bates J,
Young EJ,
Ding Q,
Shum C,
D'Abate L,
Bradley CA,
Rutherford A,
Aguda V,
Apresto B,
Chen N,
Desai S,
Du X,
Fong MLY,
Pullenayegum S,
Samler K,
Wang T,
Ho K,
Paton T,
Pereira SL,
Herbrick JA,
Wintle RF,
Fuerth J,
Noppornpitak J,
Ward H,
Magee P,
Al Baz A,
Kajendirarajah U,
Kapadia S,
Vlasblom J,
Valluri M,
Green J,
Seifer V,
Quirbach M,
Rennie O,
Kelley E,
Masjedi N,
Lord C,
Szego MJ,
Zawati MH,
Lang M,
Strug LJ,
Marshall CR,
Costain G,
Calli K,
Iaboni A,
Yusuf A,
Ambrozewicz P,
Gallagher L,
Amaral DG,
Brian J,
Elsabbagh M,
Georgiades S,
Messinger DS,
Ozonoff S,
Sebat J,
Sjaarda C,
Smith IM,
Szatmari P,
Zwaigenbaum L,
Kushki A,
Frazier TW,
Vorstman JAS,
Fakhro KA,
Fernandez BA,
Lewis MES,
Weksberg R,
Fiume M,
Yuen RKC,
Anagnostou E,
Sondheimer N,
Glazer D,
Hartley DM,
Scherer SW</span><br />
<span class="medgenPMjournal">Cell</span>
2022 Nov 10;185(23):4409-4427.e18.
doi: 10.1016/j.cell.2022.10.009.
<span class="bold">PMID: </span><a href="/pubmed/36368308" target="_blank">36368308</a><a href="/pmc/articles/PMC10726699" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35982160">Rare coding variation provides insight into the genetic architecture and phenotypic context of autism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fu JM,
Satterstrom FK,
Peng M,
Brand H,
Collins RL,
Dong S,
Wamsley B,
Klei L,
Wang L,
Hao SP,
Stevens CR,
Cusick C,
Babadi M,
Banks E,
Collins B,
Dodge S,
Gabriel SB,
Gauthier L,
Lee SK,
Liang L,
Ljungdahl A,
Mahjani B,
Sloofman L,
Smirnov AN,
Barbosa M,
Betancur C,
Brusco A,
Chung BHY,
Cook EH,
Cuccaro ML,
Domenici E,
Ferrero GB,
Gargus JJ,
Herman GE,
Hertz-Picciotto I,
Maciel P,
Manoach DS,
Passos-Bueno MR,
Persico AM,
Renieri A,
Sutcliffe JS,
Tassone F,
Trabetti E,
Campos G,
Cardaropoli S,
Carli D,
Chan MCY,
Fallerini C,
Giorgio E,
Girardi AC,
Hansen-Kiss E,
Lee SL,
Lintas C,
Ludena Y,
Nguyen R,
Pavinato L,
Pericak-Vance M,
Pessah IN,
Schmidt RJ,
Smith M,
Costa CIS,
Trajkova S,
Wang JYT,
Yu MHC;
Autism Sequencing Consortium (ASC);
Broad Institute Center for Common Disease Genomics (Broad-CCDG);
iPSYCH-BROAD Consortium,
Cutler DJ,
De Rubeis S,
Buxbaum JD,
Daly MJ,
Devlin B,
Roeder K,
Sanders SJ,
Talkowski ME</span><br />
<span class="medgenPMjournal">Nat Genet</span>
2022 Sep;54(9):1320-1331.
Epub 2022 Aug 18
doi: 10.1038/s41588-022-01104-0.
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<div class="portlet_content ln"><span class="medgenPMauthor">Zhou X,
Feliciano P,
Shu C,
Wang T,
Astrovskaya I,
Hall JB,
Obiajulu JU,
Wright JR,
Murali SC,
Xu SX,
Brueggeman L,
Thomas TR,
Marchenko O,
Fleisch C,
Barns SD,
Snyder LG,
Han B,
Chang TS,
Turner TN,
Harvey WT,
Nishida A,
O'Roak BJ,
Geschwind DH;
SPARK Consortium,
Michaelson JJ,
Volfovsky N,
Eichler EE,
Shen Y,
Chung WK</span><br />
<span class="medgenPMjournal">Nat Genet</span>
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<span class="bold">PMID: </span><a href="/pubmed/35982159" target="_blank">35982159</a><a href="/pmc/articles/PMC9470534" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32472753">Risk factors, diagnosis, prognosis and treatment of autism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Styles M,
Alsharshani D,
Samara M,
Alsharshani M,
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<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
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<span class="bold">PMID: </span><a href="/pubmed/32472753" target="_blank">32472753</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">De Rubeis S,
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Liu L,
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Yuen RK;
DDD Study;
Homozygosity Mapping Collaborative for Autism;
UK10K Consortium,
Cook EH,
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Hultman CM,
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Palotie A,
Schellenberg GD,
Sklar P,
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<span class="medgenPMjournal">Nature</span>
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<span class="bold">PMID: </span><a href="/pubmed/25363760" target="_blank">25363760</a><a href="/pmc/articles/PMC4402723" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%209%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (291)</a></div><h3 class="subhead">Diagnosis</h3>
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<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
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<div class="portlet_content ln"><span class="medgenPMauthor">Sandin S,
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<span class="bold">PMID: </span><a href="/pubmed/24794370" target="_blank">24794370</a><a href="/pmc/articles/PMC4381277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
Xie T,
Vos M,
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<span class="medgenPMjournal">Transl Psychiatry</span>
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<div class="portlet_content ln"><span class="medgenPMauthor">Vaez M,
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Georgii Hellberg KL,
Dehkordi SR,
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Bybjerg-Grauholm J,
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Hougaard DM,
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<span class="medgenPMjournal">JAMA Psychiatry</span>
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<span class="bold">PMID: </span><a href="/pubmed/38922630" target="_blank">38922630</a><a href="/pmc/articles/PMC11209205" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Cheng CM,
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<span class="medgenPMjournal">JAMA Psychiatry</span>
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<span class="bold">PMID: </span><a href="/pubmed/38568605" target="_blank">38568605</a><a href="/pmc/articles/PMC10993159" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/32045779" target="_blank">32045779</a><a href="/pmc/articles/PMC8453372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Manning-Courtney P,
Brown J,
Molloy CA,
Reinhold J,
Murray D,
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<span class="medgenPMjournal">Curr Probl Pediatr Adolesc Health Care</span>
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<span class="bold">PMID: </span><a href="/pubmed/14534514" target="_blank">14534514</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%209%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (41)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36309498">Genome-wide rare variant score associates with morphological subtypes of autism spectrum disorder.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chan AJS,
Engchuan W,
Reuter MS,
Wang Z,
Thiruvahindrapuram B,
Trost B,
Nalpathamkalam T,
Negrijn C,
Lamoureux S,
Pellecchia G,
Patel RV,
Sung WWL,
MacDonald JR,
Howe JL,
Vorstman J,
Sondheimer N,
Takahashi N,
Miles JH,
Anagnostou E,
Tammimies K,
Zarrei M,
Merico D,
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Yuen RKC,
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<span class="medgenPMjournal">Nat Commun</span>
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<span class="bold">PMID: </span><a href="/pubmed/36309498" target="_blank">36309498</a><a href="/pmc/articles/PMC9617891" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32472753">Risk factors, diagnosis, prognosis and treatment of autism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Styles M,
Alsharshani D,
Samara M,
Alsharshani M,
Khattab A,
Qoronfleh MW,
Al-Dewik NI</span><br />
<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
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<span class="bold">PMID: </span><a href="/pubmed/32472753" target="_blank">32472753</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Taylor MJ,
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<span class="bold">PMID: </span><a href="/pubmed/32374377" target="_blank">32374377</a><a href="/pmc/articles/PMC7203675" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31110234">A novel de novo frameshift variant in SETD1B causes epilepsy.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/14534514">Diagnosis and treatment of autism spectrum disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Manning-Courtney P,
Brown J,
Molloy CA,
Reinhold J,
Murray D,
Sorensen-Burnworth R,
Messerschmidt T,
Kent B</span><br />
<span class="medgenPMjournal">Curr Probl Pediatr Adolesc Health Care</span>
2003 Oct;33(9):283-304.
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<span class="bold">PMID: </span><a href="/pubmed/14534514" target="_blank">14534514</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%209%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (65)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37704762">Single-cell brain organoid screening identifies developmental defects in autism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li C,
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Broad Institute Center for Common Disease Genomics (Broad-CCDG);
iPSYCH-BROAD Consortium,
Cutler DJ,
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Epub 2017 Feb 13
doi: 10.1038/ng.3789.
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<div class="nl"><a target="_blank" href="/pubmed/23934111">De novo mutations in epileptic encephalopathies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Epi4K Consortium;
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Allen AS,
Berkovic SF,
Cossette P,
Delanty N,
Dlugos D,
Eichler EE,
Epstein MP,
Glauser T,
Goldstein DB,
Han Y,
Heinzen EL,
Hitomi Y,
Howell KB,
Johnson MR,
Kuzniecky R,
Lowenstein DH,
Lu YF,
Madou MR,
Marson AG,
Mefford HC,
Esmaeeli Nieh S,
O'Brien TJ,
Ottman R,
Petrovski S,
Poduri A,
Ruzzo EK,
Scheffer IE,
Sherr EH,
Yuskaitis CJ,
Abou-Khalil B,
Alldredge BK,
Bautista JF,
Berkovic SF,
Boro A,
Cascino GD,
Consalvo D,
Crumrine P,
Devinsky O,
Dlugos D,
Epstein MP,
Fiol M,
Fountain NB,
French J,
Friedman D,
Geller EB,
Glauser T,
Glynn S,
Haut SR,
Hayward J,
Helmers SL,
Joshi S,
Kanner A,
Kirsch HE,
Knowlton RC,
Kossoff EH,
Kuperman R,
Kuzniecky R,
Lowenstein DH,
McGuire SM,
Motika PV,
Novotny EJ,
Ottman R,
Paolicchi JM,
Parent JM,
Park K,
Poduri A,
Scheffer IE,
Shellhaas RA,
Sherr EH,
Shih JJ,
Singh R,
Sirven J,
Smith MC,
Sullivan J,
Lin Thio L,
Venkat A,
Vining EP,
Von Allmen GK,
Weisenberg JL,
Widdess-Walsh P,
Winawer MR</span><br />
<span class="medgenPMjournal">Nature</span>
2013 Sep 12;501(7466):217-21.
Epub 2013 Aug 11
doi: 10.1038/nature12439.
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<span class="medgenPMjournal">Genet Med</span>
2025 Jan;27(1):101227.
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<div class="nl"><a target="_blank" href="/pubmed/38732157">Bridging Genetic Insights with Neuroimaging in Autism Spectrum Disorder-A Systematic Review.</a></div>
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Rasga C,
Santos JX,
Martiniano H,
Marques AR,
Oliveira G,
Vicente AM</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2024 Apr 30;25(9)
doi: 10.3390/ijms25094938.
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<div class="nl"><a target="_blank" href="/pubmed/36429911">Special Care Patients and Caries Prevalence in Permanent Dentition: A Systematic Review.</a></div>
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Pecci-Lloret MP,
Rodríguez-Lozano FJ</span><br />
<span class="medgenPMjournal">Int J Environ Res Public Health</span>
2022 Nov 17;19(22)
doi: 10.3390/ijerph192215194.
<span class="bold">PMID: </span><a href="/pubmed/36429911" target="_blank">36429911</a><a href="/pmc/articles/PMC9690089" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32045779">Phthalate exposure and neurodevelopment: A systematic review and meta-analysis of human epidemiological evidence.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Radke EG,
Braun JM,
Nachman RM,
Cooper GS</span><br />
<span class="medgenPMjournal">Environ Int</span>
2020 Apr;137:105408.
Epub 2020 Feb 8
doi: 10.1016/j.envint.2019.105408.
<span class="bold">PMID: </span><a href="/pubmed/32045779" target="_blank">32045779</a><a href="/pmc/articles/PMC8453372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30182779">Genetic susceptibility to cerebrovascular disease: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Griessenauer CJ,
Farrell S,
Sarkar A,
Zand R,
Abedi V,
Holland N,
Michael A,
Cummings CL,
Metpally R,
Carey DJ,
Goren O,
Martin N,
Hendrix P,
Schirmer CM</span><br />
<span class="medgenPMjournal">J Cereb Blood Flow Metab</span>
2018 Nov;38(11):1853-1871.
Epub 2018 Sep 5
doi: 10.1177/0271678X18797958.
<span class="bold">PMID: </span><a href="/pubmed/30182779" target="_blank">30182779</a><a href="/pmc/articles/PMC6259318" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Autism%2C%20susceptibility%20to%2C%209%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div></div>
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