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<meta name="keywords" content="C1266158, germ cell tumor, nonseminomatous, neoplastic process, non-dysgerminomatous germ cell tumor, non-dysgerminomatous germ cell tumour, non-germinomatous germ cell tumor, non-germinomatous germ cell tumour, non-seminomatous germ cell tumor, non-seminomatous germ cell tumour, non-seminomatous germ-cell tumors, nongerminomatous germ cell tumor, nongerminomatous germ cell tumor including central nervous system, nongerminomatous germ cell tumour, nongerminomatous germ cell tumour including central nervous system, nonseminomatous germ cell tumor, nonseminomatous germ cell tumors, nonseminomatous germ cell tumors, somatic, nsgct, nsgct nonseminomatous germ cell tumor, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A term that refers to teratoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, or mixed forms of these tumors." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Nongerminomatous germ cell tumor (Concept Id: C1266158)
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<!--
UID=220426
ConceptID=C1266158
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Nongerminomatous germ cell tumor</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>220426</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1266158</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Germ cell tumor, nonseminomatous; Non-seminomatous germ-cell tumors; NONSEMINOMATOUS GERM CELL TUMORS, SOMATIC</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Germ cell tumor, nonseminomatous (128766005)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0021656" target="_blank">MONDO:0021656</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/273300" target="_blank">273300</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A term that refers to teratoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, or mixed forms of these tumors. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=220426" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=220426" ref="ncbi_uid=220426">V</a></span></span><span class="TLline">Nongerminomatous germ cell tumor</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/99182" ref="tree=MeSH" title="MedGen record for Neoplasm by Morphology">Neoplasm by Morphology</a></span><ul><li><span class="TLline"><a href="/medgen/60030" ref="tree=MeSH" title="MedGen record for Germ cell tumor">Germ cell tumor</a></span><ul><li><span class="matched_ds">Nongerminomatous germ cell tumor</span><ul><li><span class="TLline"><a href="/medgen/760465" ref="tree=MeSH" title="MedGen record for Central nervous system nongerminomatous germ cell tumor">Central nervous system nongerminomatous germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/234105" ref="tree=MeSH" title="MedGen record for Central nervous system teratoma">Central nervous system teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/234583" ref="tree=MeSH" title="MedGen record for Adult central nervous system teratoma">Adult central nervous system teratoma</a></span></li><li><span class="TLline"><a href="/medgen/272442" ref="tree=MeSH" title="MedGen record for Central nervous system immature teratoma">Central nervous system immature teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234103" ref="tree=MeSH" title="MedGen record for Central nervous system mature teratoma">Central nervous system mature teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234418" ref="tree=MeSH" title="MedGen record for Central Nervous System Teratoma with Malignant Transformation">Central Nervous System Teratoma with Malignant Transformation</a></span></li><li><span class="TLline"><a href="/medgen/234602" ref="tree=MeSH" title="MedGen record for Childhood Central Nervous System Teratoma">Childhood Central Nervous System Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/277517" ref="tree=MeSH" title="MedGen record for Pineal region teratoma">Pineal region teratoma</a></span></li><li><span class="TLline"><a href="/medgen/1657063" ref="tree=MeSH" title="MedGen record for Sellar Teratoma">Sellar Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/233575" ref="tree=MeSH" title="MedGen record for Spinal cord intramedullary teratoma">Spinal cord intramedullary teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234100" ref="tree=MeSH" title="MedGen record for Choriocarcinoma of the central nervous system">Choriocarcinoma of the central nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/234582" ref="tree=MeSH" title="MedGen record for Adult central nervous system choriocarcinoma">Adult central nervous system choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234603" ref="tree=MeSH" title="MedGen record for Pediatric CNS choriocarcinoma">Pediatric CNS choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233327" ref="tree=MeSH" title="MedGen record for Pineal region choriocarcinoma">Pineal region choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1662085" ref="tree=MeSH" title="MedGen record for Sellar Choriocarcinoma">Sellar Choriocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272566" ref="tree=MeSH" title="MedGen record for Embryonal carcinoma of the central nervous system">Embryonal carcinoma of the central nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/234580" ref="tree=MeSH" title="MedGen record for Adult central nervous system embryonal carcinoma">Adult central nervous system embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277988" ref="tree=MeSH" title="MedGen record for Childhood central nervous system embryonal carcinoma">Childhood central nervous system embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1650933" ref="tree=MeSH" title="MedGen record for Sellar Embryonal Carcinoma">Sellar Embryonal Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234492" ref="tree=MeSH" title="MedGen record for Yolk sac tumor of central nervous system">Yolk sac tumor of central nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/234604" ref="tree=MeSH" title="MedGen record for Central nervous system endodermal sinus tumor">Central nervous system endodermal sinus tumor</a></span></li><li><span class="TLline"><a href="/medgen/277518" ref="tree=MeSH" title="MedGen record for Pineal region yolk sac tumor">Pineal region yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/1669021" ref="tree=MeSH" title="MedGen record for Sellar Yolk Sac Tumor">Sellar Yolk Sac Tumor</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/903302" ref="tree=MeSH" title="MedGen record for Childhood Nongerminomatous Germ Cell Tumor">Childhood Nongerminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/901410" ref="tree=MeSH" title="MedGen record for Childhood Choriocarcinoma">Childhood Choriocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/234135" ref="tree=MeSH" title="MedGen record for Childhood choriocarcinoma of the ovary">Childhood choriocarcinoma of the ovary</a></span></li><li><span class="TLline"><a href="/medgen/272469" ref="tree=MeSH" title="MedGen record for Childhood testicular choriocarcinoma">Childhood testicular choriocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/895969" ref="tree=MeSH" title="MedGen record for Childhood Embryonal Carcinoma">Childhood Embryonal Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/272470" ref="tree=MeSH" title="MedGen record for Childhood embryonal testis carcinoma">Childhood embryonal testis carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232352" ref="tree=MeSH" title="MedGen record for Childhood ovarian embryonal carcinoma">Childhood ovarian embryonal carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234139" ref="tree=MeSH" title="MedGen record for Childhood endodermal sinus tumor">Childhood endodermal sinus tumor</a></span><ul><li><span class="TLline"><a href="/medgen/234136" ref="tree=MeSH" title="MedGen record for Childhood ovarian yolk sac tumor">Childhood ovarian yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/272473" ref="tree=MeSH" title="MedGen record for Childhood Testicular Yolk Sac Tumor">Childhood Testicular Yolk Sac Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/899770" ref="tree=MeSH" title="MedGen record for Childhood Ovarian Nongerminomatous Germ Cell Tumor">Childhood Ovarian Nongerminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/272466" ref="tree=MeSH" title="MedGen record for Childhood teratoma of the ovary">Childhood teratoma of the ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/384872" ref="tree=MeSH" title="MedGen record for Childhood Teratoma">Childhood Teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/895296" ref="tree=MeSH" title="MedGen record for Childhood Immature Teratoma">Childhood Immature Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/905598" ref="tree=MeSH" title="MedGen record for Childhood Mature Teratoma">Childhood Mature Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234138" ref="tree=MeSH" title="MedGen record for Childhood Testicular Teratoma">Childhood Testicular Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/901672" ref="tree=MeSH" title="MedGen record for Childhood Testicular Non-Seminomatous Germ Cell Tumor">Childhood Testicular Non-Seminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/234137" ref="tree=MeSH" title="MedGen record for Childhood testicular mixed embryonal carcinoma and teratoma">Childhood testicular mixed embryonal carcinoma and teratoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/61653" ref="tree=MeSH" title="MedGen record for Embryonal carcinoma">Embryonal carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/208964" ref="tree=MeSH" title="MedGen record for Extragonadal Embryonal Carcinoma">Extragonadal Embryonal Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233677" ref="tree=MeSH" title="MedGen record for Mediastinal Embryonal Carcinoma">Mediastinal Embryonal Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1842755" ref="tree=MeSH" title="MedGen record for Non-central nervous system-localized embryonal carcinoma">Non-central nervous system-localized embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/91090" ref="tree=MeSH" title="MedGen record for Ovarian embryonal carcinoma">Ovarian embryonal carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/277761" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236906" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236896" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234888" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7">Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/66771" ref="tree=MeSH" title="MedGen record for Testicular embryonal carcinoma">Testicular embryonal carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233470" ref="tree=MeSH" title="MedGen record for Intratubular Non-Seminoma">Intratubular Non-Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/163531" ref="tree=MeSH" title="MedGen record for Stage I Testicular Embryonal Carcinoma AJCC v6 and v7">Stage I Testicular Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163532" ref="tree=MeSH" title="MedGen record for Stage II Testicular Embryonal Carcinoma AJCC v6 and v7">Stage II Testicular Embryonal Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/208971" ref="tree=MeSH" title="MedGen record for Stage III Testicular Embryonal Carcinoma AJCC v6 and v7">Stage III Testicular Embryonal Carcinoma AJCC v6 and v7</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/233662" ref="tree=MeSH" title="MedGen record for Extragonadal nonseminomatous germ cell tumor">Extragonadal nonseminomatous germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/459624" ref="tree=MeSH" title="MedGen record for Gastric choriocarcinoma">Gastric choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277351" ref="tree=MeSH" title="MedGen record for Malignant Mediastinal Nongerminomatous Germ Cell Tumor">Malignant Mediastinal Nongerminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/313417" ref="tree=MeSH" title="MedGen record for Malignant Mediastinal Germ Cell Tumor with Associated Hematologic Malignancy">Malignant Mediastinal Germ Cell Tumor with Associated Hematologic Malignancy</a></span></li><li><span class="TLline"><a href="/medgen/235307" ref="tree=MeSH" title="MedGen record for Mediastinal Choriocarcinoma">Mediastinal Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233173" ref="tree=MeSH" title="MedGen record for Mediastinal Mixed Nongerminomatous Germ Cell Tumor">Mediastinal Mixed Nongerminomatous Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/233176" ref="tree=MeSH" title="MedGen record for Mediastinal yolk sac tumor">Mediastinal yolk sac tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/857329" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Extragonadal Nongerminomatous Germ Cell Tumor">Recurrent Malignant Extragonadal Nongerminomatous Germ Cell Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1791049" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Nongerminomatous Germ Cell Tumor">Metastatic Malignant Nongerminomatous Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/769623" ref="tree=MeSH" title="MedGen record for Ovarian Non-Dysgerminomatous Germ Cell Tumor">Ovarian Non-Dysgerminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/274798" ref="tree=MeSH" title="MedGen record for Non-gestational ovarian choriocarcinoma">Non-gestational ovarian choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83415" ref="tree=MeSH" title="MedGen record for Ovarian yolk sac tumor">Ovarian yolk sac tumor</a></span><ul><li><span class="TLline"><a href="/medgen/309520" ref="tree=MeSH" title="MedGen record for Ovarian yolk sac tumor, glandular pattern">Ovarian yolk sac tumor, glandular pattern</a></span></li><li><span class="TLline"><a href="/medgen/276676" ref="tree=MeSH" title="MedGen record for Ovarian yolk sac tumor, hepatoid pattern">Ovarian yolk sac tumor, hepatoid pattern</a></span></li><li><span class="TLline"><a href="/medgen/309521" ref="tree=MeSH" title="MedGen record for Ovarian yolk sac tumor, polyvesicular vitelline pattern">Ovarian yolk sac tumor, polyvesicular vitelline pattern</a></span></li><li><span class="TLline"><a href="/medgen/277762" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234856" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236897" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234890" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7">Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/271323" ref="tree=MeSH" title="MedGen record for Polyembryoma of the ovary">Polyembryoma of the ovary</a></span><ul><li><span class="TLline"><a href="/medgen/234359" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Polyembryoma AJCC v6 and v7">Stage I Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236907" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Polyembryoma AJCC v6 and v7">Stage II Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277714" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Polyembryoma AJCC v6 and v7">Stage III Ovarian Polyembryoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234889" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Polyembryoma AJCC v6 and v7">Stage IV Ovarian Polyembryoma AJCC v6 and v7</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1791050" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Nongerminomatous Germ Cell Tumor">Recurrent Malignant Nongerminomatous Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/104913" ref="tree=MeSH" title="MedGen record for Teratocarcinoma">Teratocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233172" ref="tree=MeSH" title="MedGen record for Mediastinal Mixed Embryonal Carcinoma and Teratoma">Mediastinal Mixed Embryonal Carcinoma and Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/277812" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Teratoma">Testicular Mixed Embryonal Carcinoma and Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/21097" ref="tree=MeSH" title="MedGen record for Teratoma">Teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/277966" ref="tree=MeSH" title="MedGen record for Adult teratoma">Adult teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/235084" ref="tree=MeSH" title="MedGen record for Adult cystic teratoma">Adult cystic teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/361206" ref="tree=MeSH" title="MedGen record for Benign teratoma">Benign teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/1666963" ref="tree=MeSH" title="MedGen record for Grade 1 Teratoma">Grade 1 Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/277967" ref="tree=MeSH" title="MedGen record for Mature teratoma">Mature teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/488953" ref="tree=MeSH" title="MedGen record for Cardiac teratoma">Cardiac teratoma</a></span></li><li><span class="TLline"><a href="/medgen/906455" ref="tree=MeSH" title="MedGen record for Craniofacial teratoma">Craniofacial teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234578" ref="tree=MeSH" title="MedGen record for Cystic teratoma">Cystic teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/41504" ref="tree=MeSH" title="MedGen record for Dermoid cyst">Dermoid cyst</a></span></li><li><span class="TLline"><a href="/medgen/235415" ref="tree=MeSH" title="MedGen record for Ovarian cystic teratoma">Ovarian cystic teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/309129" ref="tree=MeSH" title="MedGen record for Fallopian tube teratoma">Fallopian tube teratoma</a></span></li><li><span class="TLline"><a href="/medgen/272665" ref="tree=MeSH" title="MedGen record for Gastric teratoma">Gastric teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/272752" ref="tree=MeSH" title="MedGen record for Immature gastric teratoma">Immature gastric teratoma</a></span></li><li><span class="TLline"><a href="/medgen/233165" ref="tree=MeSH" title="MedGen record for Mature gastric teratoma">Mature gastric teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/475575" ref="tree=MeSH" title="MedGen record for Gonadal teratoma">Gonadal teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/76072" ref="tree=MeSH" title="MedGen record for Ovarian teratoma">Ovarian teratoma</a></span></li><li><span class="TLline"><a href="/medgen/68669" ref="tree=MeSH" title="MedGen record for Testicular teratoma">Testicular teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/90798" ref="tree=MeSH" title="MedGen record for Immature teratoma">Immature teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/167781" ref="tree=MeSH" title="MedGen record for Immature extragonadal teratoma">Immature extragonadal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/138044" ref="tree=MeSH" title="MedGen record for Immature ovarian teratoma">Immature ovarian teratoma</a></span></li><li><span class="TLline"><a href="/medgen/232636" ref="tree=MeSH" title="MedGen record for Malignant teratoma of testis">Malignant teratoma of testis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1842162" ref="tree=MeSH" title="MedGen record for Kidney teratoma">Kidney teratoma</a></span></li><li><span class="TLline"><a href="/medgen/473415" ref="tree=MeSH" title="MedGen record for Liver Teratoma">Liver Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/87525" ref="tree=MeSH" title="MedGen record for Lung Teratoma">Lung Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/1652407" ref="tree=MeSH" title="MedGen record for Malignant teratoma">Malignant teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/1657209" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Teratoma">Malignant Ovarian Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233175" ref="tree=MeSH" title="MedGen record for Mediastinal teratoma">Mediastinal teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/1656782" ref="tree=MeSH" title="MedGen record for Mediastinal Immature Teratoma">Mediastinal Immature Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/233671" ref="tree=MeSH" title="MedGen record for Mediastinal Mature Teratoma">Mediastinal Mature Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1625954" ref="tree=MeSH" title="MedGen record for Nasopharyngeal teratoma">Nasopharyngeal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/1841692" ref="tree=MeSH" title="MedGen record for Neck teratoma">Neck teratoma</a></span></li><li><span class="TLline"><a href="/medgen/459452" ref="tree=MeSH" title="MedGen record for Pancreatic Teratoma">Pancreatic Teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/453215" ref="tree=MeSH" title="MedGen record for Pancreatic Mature Teratoma">Pancreatic Mature Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1639478" ref="tree=MeSH" title="MedGen record for Pericardial Teratoma">Pericardial Teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/233673" ref="tree=MeSH" title="MedGen record for Mature pericardial teratoma">Mature pericardial teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/107852" ref="tree=MeSH" title="MedGen record for Sacrococcygeal teratoma">Sacrococcygeal teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/904094" ref="tree=MeSH" title="MedGen record for Altman type I sacrococcygeal teratoma">Altman type I sacrococcygeal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/905394" ref="tree=MeSH" title="MedGen record for Altman type II sacrococcygeal teratoma">Altman type II sacrococcygeal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/901004" ref="tree=MeSH" title="MedGen record for Altman type III sacrococcygeal teratoma">Altman type III sacrococcygeal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/1647319" ref="tree=MeSH" title="MedGen record for Presacral teratoma">Presacral teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/20977" ref="tree=MeSH" title="MedGen record for Struma ovarii">Struma ovarii</a></span><ul><li><span class="TLline"><a href="/medgen/137777" ref="tree=MeSH" title="MedGen record for Malignant struma ovarii">Malignant struma ovarii</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87256" ref="tree=MeSH" title="MedGen record for Teratoma with malignant transformation">Teratoma with malignant transformation</a></span><ul><li><span class="TLline"><a href="/medgen/1791052" ref="tree=MeSH" title="MedGen record for Ovarian Dermoid Cyst with Somatic-Type Malignancy">Ovarian Dermoid Cyst with Somatic-Type Malignancy</a></span></li><li><span class="TLline"><a href="/medgen/237006" ref="tree=MeSH" title="MedGen record for Testicular Teratoma with Somatic-Type Malignancy">Testicular Teratoma with Somatic-Type Malignancy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/328115" ref="tree=MeSH" title="MedGen record for Thyroid Gland Teratoma">Thyroid Gland Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/41782" ref="tree=MeSH" title="MedGen record for Yolk sac tumor">Yolk sac tumor</a></span><ul><li><span class="TLline"><a href="/medgen/231046" ref="tree=MeSH" title="MedGen record for Adult yolk sac tumor">Adult yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/1643931" ref="tree=MeSH" title="MedGen record for Cardiac Yolk Sac Tumor">Cardiac Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/927339" ref="tree=MeSH" title="MedGen record for Cervical Yolk Sac Tumor">Cervical Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/474711" ref="tree=MeSH" title="MedGen record for Liver Yolk Sac Tumor">Liver Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1643837" ref="tree=MeSH" title="MedGen record for Pericardial Yolk Sac Tumor">Pericardial Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/79028" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor">Testicular yolk sac tumor</a></span><ul><li><span class="TLline"><a href="/medgen/308261" ref="tree=MeSH" title="MedGen record for Enteric pattern testicular yolk sac tumor">Enteric pattern testicular yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/273638" ref="tree=MeSH" title="MedGen record for Polyvesicular vitelline pattern testicular yolk sac tumor">Polyvesicular vitelline pattern testicular yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/271773" ref="tree=MeSH" title="MedGen record for Reticular pattern testicular yolk sac tumor">Reticular pattern testicular yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/167787" ref="tree=MeSH" title="MedGen record for Stage I Testicular Yolk Sac Tumor AJCC v6 and v7">Stage I Testicular Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/208973" ref="tree=MeSH" title="MedGen record for Stage II Testicular Yolk Sac Tumor AJCC v6 and v7">Stage II Testicular Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163619" ref="tree=MeSH" title="MedGen record for Stage III Testicular Yolk Sac Tumor AJCC v6 and v7">Stage III Testicular Yolk Sac Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/273636" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, endodermal sinus pattern">Testicular yolk sac tumor, endodermal sinus pattern</a></span></li><li><span class="TLline"><a href="/medgen/273637" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, glandular-alveolar pattern">Testicular yolk sac tumor, glandular-alveolar pattern</a></span></li><li><span class="TLline"><a href="/medgen/272846" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, hepatoid pattern">Testicular yolk sac tumor, hepatoid pattern</a></span></li><li><span class="TLline"><a href="/medgen/271772" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, macrocystic pattern">Testicular yolk sac tumor, macrocystic pattern</a></span></li><li><span class="TLline"><a href="/medgen/271774" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, myxomatous pattern">Testicular yolk sac tumor, myxomatous pattern</a></span></li><li><span class="TLline"><a href="/medgen/308262" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, papillary pattern">Testicular yolk sac tumor, papillary pattern</a></span></li><li><span class="TLline"><a href="/medgen/308263" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor, solid pattern">Testicular yolk sac tumor, solid pattern</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234985" ref="tree=MeSH" title="MedGen record for Vaginal yolk sac tumor">Vaginal yolk sac tumor</a></span></li><li><span class="TLline"><a href="/medgen/925530" ref="tree=MeSH" title="MedGen record for Vulvar Yolk Sac Tumor">Vulvar Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1791547" ref="tree=MeSH" title="MedGen record for Yolk Sac Tumor with Somatic-Type Malignancy">Yolk Sac Tumor with Somatic-Type Malignancy</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/21563173">Longitudinal evaluation of neurocognitive function after treatment for central nervous system germ cell tumors in childhood.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mabbott DJ,
Monsalves E,
Spiegler BJ,
Bartels U,
Janzen L,
Guger S,
Laperriere N,
Andrews N,
Bouffet E</span><br />
<span class="medgenPMjournal">Cancer</span>
2011 Dec 1;117(23):5402-11.
Epub 2011 May 11
doi: 10.1002/cncr.26127.
<span class="bold">PMID: </span><a href="/pubmed/21563173" target="_blank">21563173</a></div>
<div class="nl"><a target="_blank" href="/pubmed/19841431">Central nervous system germ cell tumors: classification, clinical features, and treatment with a historical overview.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fujimaki T</span><br />
<span class="medgenPMjournal">J Child Neurol</span>
2009 Nov;24(11):1439-45.
doi: 10.1177/0883073809342127.
<span class="bold">PMID: </span><a href="/pubmed/19841431" target="_blank">19841431</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7514765">Treatment of nongerminomatous germ-cell tumors of the pineal region.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Herrmann HD,
Westphal M,
Winkler K,
Laas RW,
Schulte FJ</span><br />
<span class="medgenPMjournal">Neurosurgery</span>
1994 Mar;34(3):524-9; discussion 529.
doi: 10.1227/00006123-199403000-00021.
<span class="bold">PMID: </span><a href="/pubmed/7514765" target="_blank">7514765</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22nongerminomatous%20germ%20cell%20tumor%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/testicular.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Testicular Cancer, 2024</a></h3>
</div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36342135">Split-Tendon Medial Transposition of Lateral Rectus for Pediatric Complete Oculomotor Palsy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang KX,
Varma H,
Cao Y,
Shah VS</span><br />
<span class="medgenPMjournal">J Neuroophthalmol</span>
2023 Jun 1;43(2):254-260.
Epub 2022 Nov 7
doi: 10.1097/WNO.0000000000001731.
<span class="bold">PMID: </span><a href="/pubmed/36342135" target="_blank">36342135</a><a href="/pmc/articles/PMC10166200" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36131594">Feasibility of treating pediatric intracranial germ cell tumors in a middle-income country: The Jordanian experience.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amayiri N,
Sarhan N,
Yousef Y,
Ibrahimi AK,
Abu-Shanab S,
Al-Zebin Z,
Al-Hussaini M,
Musharbash A,
Tawalbeh A,
Bouffet E,
Bartels U</span><br />
<span class="medgenPMjournal">Pediatr Blood Cancer</span>
2022 Dec;69(12):e30011.
Epub 2022 Sep 21
doi: 10.1002/pbc.30011.
<span class="bold">PMID: </span><a href="/pubmed/36131594" target="_blank">36131594</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31751614">Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tsuyuguchi S,
Sugiyama K,
Kinoshita Y,
Kolakshyapati M,
Takayasu T,
Usui S,
Takano M,
Yonezawa U,
Taguchi A,
Amatya VJ,
Takeshima Y,
Kurisu K,
Yamasaki F</span><br />
<span class="medgenPMjournal">World Neurosurg</span>
2020 Feb;134:e360-e371.
Epub 2019 Nov 18
doi: 10.1016/j.wneu.2019.10.074.
<span class="bold">PMID: </span><a href="/pubmed/31751614" target="_blank">31751614</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25062305">Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Teo WY,
Ross J,
Bollo RJ,
Seow WT,
Tan AM,
Kang SG,
Kim DS,
Li XN,
Lau CC,
Mohila CA,
Adesina AM,
Su JM</span><br />
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
2014 Oct;14(4):348-55.
Epub 2014 Jul 25
doi: 10.3171/2014.6.PEDS13651.
<span class="bold">PMID: </span><a href="/pubmed/25062305" target="_blank">25062305</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7514765">Treatment of nongerminomatous germ-cell tumors of the pineal region.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Herrmann HD,
Westphal M,
Winkler K,
Laas RW,
Schulte FJ</span><br />
<span class="medgenPMjournal">Neurosurgery</span>
1994 Mar;34(3):524-9; discussion 529.
doi: 10.1227/00006123-199403000-00021.
<span class="bold">PMID: </span><a href="/pubmed/7514765" target="_blank">7514765</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/31751614">Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tsuyuguchi S,
Sugiyama K,
Kinoshita Y,
Kolakshyapati M,
Takayasu T,
Usui S,
Takano M,
Yonezawa U,
Taguchi A,
Amatya VJ,
Takeshima Y,
Kurisu K,
Yamasaki F</span><br />
<span class="medgenPMjournal">World Neurosurg</span>
2020 Feb;134:e360-e371.
Epub 2019 Nov 18
doi: 10.1016/j.wneu.2019.10.074.
<span class="bold">PMID: </span><a href="/pubmed/31751614" target="_blank">31751614</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29848146">Central Nervous System Germ Cell Tumors: A Review of the Literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kong Z,
Wang Y,
Dai C,
Yao Y,
Ma W,
Wang Y</span><br />
<span class="medgenPMjournal">J Child Neurol</span>
2018 Aug;33(9):610-620.
Epub 2018 May 30
doi: 10.1177/0883073818772470.
<span class="bold">PMID: </span><a href="/pubmed/29848146" target="_blank">29848146</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25062305">Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Teo WY,
Ross J,
Bollo RJ,
Seow WT,
Tan AM,
Kang SG,
Kim DS,
Li XN,
Lau CC,
Mohila CA,
Adesina AM,
Su JM</span><br />
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
2014 Oct;14(4):348-55.
Epub 2014 Jul 25
doi: 10.3171/2014.6.PEDS13651.
<span class="bold">PMID: </span><a href="/pubmed/25062305" target="_blank">25062305</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22215101">Extraneural metastasis of a nongerminomatous germ cell tumor of the central nervous system in a pediatric patient with a ventriculoperitoneal shunt: a case report and review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Belongia M,
Jogal S</span><br />
<span class="medgenPMjournal">J Pediatr Hematol Oncol</span>
2012 Jan;34(1):e12-6.
doi: 10.1097/MPH.0b013e31823dd370.
<span class="bold">PMID: </span><a href="/pubmed/22215101" target="_blank">22215101</a></div>
<div class="nl"><a target="_blank" href="/pubmed/19841431">Central nervous system germ cell tumors: classification, clinical features, and treatment with a historical overview.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fujimaki T</span><br />
<span class="medgenPMjournal">J Child Neurol</span>
2009 Nov;24(11):1439-45.
doi: 10.1177/0883073809342127.
<span class="bold">PMID: </span><a href="/pubmed/19841431" target="_blank">19841431</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (36)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38629258">Off-label prescribing of immune checkpoint inhibitor therapy at a single pediatric cancer center.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gikandi A,
Chi SN,
Yeo KK,
O'Neill AF,
Shulman DS,
DuBois SG,
Collins NB</span><br />
<span class="medgenPMjournal">Cancer Med</span>
2024 Apr;13(8):e7154.
doi: 10.1002/cam4.7154.
<span class="bold">PMID: </span><a href="/pubmed/38629258" target="_blank">38629258</a><a href="/pmc/articles/PMC11022150" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36131594">Feasibility of treating pediatric intracranial germ cell tumors in a middle-income country: The Jordanian experience.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amayiri N,
Sarhan N,
Yousef Y,
Ibrahimi AK,
Abu-Shanab S,
Al-Zebin Z,
Al-Hussaini M,
Musharbash A,
Tawalbeh A,
Bouffet E,
Bartels U</span><br />
<span class="medgenPMjournal">Pediatr Blood Cancer</span>
2022 Dec;69(12):e30011.
Epub 2022 Sep 21
doi: 10.1002/pbc.30011.
<span class="bold">PMID: </span><a href="/pubmed/36131594" target="_blank">36131594</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9307195">The growing teratoma syndrome in a nongerminomatous germ cell tumor of the pineal gland: a case report and review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">O'Callaghan AM,
Katapodis O,
Ellison DW,
Theaker JM,
Mead GM</span><br />
<span class="medgenPMjournal">Cancer</span>
1997 Sep 1;80(5):942-7.
doi: 10.1002/(sici)1097-0142(19970901)80:5&lt;942::aid-cncr16&gt;3.0.co;2-w.
<span class="bold">PMID: </span><a href="/pubmed/9307195" target="_blank">9307195</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7514765">Treatment of nongerminomatous germ-cell tumors of the pineal region.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Herrmann HD,
Westphal M,
Winkler K,
Laas RW,
Schulte FJ</span><br />
<span class="medgenPMjournal">Neurosurgery</span>
1994 Mar;34(3):524-9; discussion 529.
doi: 10.1227/00006123-199403000-00021.
<span class="bold">PMID: </span><a href="/pubmed/7514765" target="_blank">7514765</a></div>
<div class="nl"><a target="_blank" href="/pubmed/2477515">Control of extraneural metastasis of a primary intracranial nongerminomatous germ-cell tumor. Case report.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Watterson J,
Priest JR</span><br />
<span class="medgenPMjournal">J Neurosurg</span>
1989 Oct;71(4):601-4.
doi: 10.3171/jns.1989.71.4.0601.
<span class="bold">PMID: </span><a href="/pubmed/2477515" target="_blank">2477515</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/25413617">Apparent diffusion coefficient of intracranial germ cell tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ogiwara H,
Tsutsumi Y,
Matsuoka K,
Kiyotani C,
Terashima K,
Morota N</span><br />
<span class="medgenPMjournal">J Neurooncol</span>
2015 Feb;121(3):565-71.
Epub 2014 Nov 21
doi: 10.1007/s11060-014-1668-y.
<span class="bold">PMID: </span><a href="/pubmed/25413617" target="_blank">25413617</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25062305">Atypical location and clinical behavior of a subset of intracranial germ cell tumors in children younger than 3 years of age.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Teo WY,
Ross J,
Bollo RJ,
Seow WT,
Tan AM,
Kang SG,
Kim DS,
Li XN,
Lau CC,
Mohila CA,
Adesina AM,
Su JM</span><br />
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
2014 Oct;14(4):348-55.
Epub 2014 Jul 25
doi: 10.3171/2014.6.PEDS13651.
<span class="bold">PMID: </span><a href="/pubmed/25062305" target="_blank">25062305</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10582672">Treatment of intracranial nongerminomatous germ-cell tumor by high-dose chemotherapy and autologous stem-cell rescue.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tada T,
Takizawa T,
Nakazato F,
Kobayashi S,
Koike K,
Oguchi M,
Ishii E,
Amano Y</span><br />
<span class="medgenPMjournal">J Neurooncol</span>
1999 Aug;44(1):71-6.
doi: 10.1023/a:1006395719917.
<span class="bold">PMID: </span><a href="/pubmed/10582672" target="_blank">10582672</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10550589">Germ cell tumors of the CNS in children: recent advances in therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Diez B,
Balmaceda C,
Matsutani M,
Weiner HL</span><br />
<span class="medgenPMjournal">Childs Nerv Syst</span>
1999 Oct;15(10):578-85.
doi: 10.1007/s003810050546.
<span class="bold">PMID: </span><a href="/pubmed/10550589" target="_blank">10550589</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7514765">Treatment of nongerminomatous germ-cell tumors of the pineal region.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Herrmann HD,
Westphal M,
Winkler K,
Laas RW,
Schulte FJ</span><br />
<span class="medgenPMjournal">Neurosurgery</span>
1994 Mar;34(3):524-9; discussion 529.
doi: 10.1227/00006123-199403000-00021.
<span class="bold">PMID: </span><a href="/pubmed/7514765" target="_blank">7514765</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/36342135">Split-Tendon Medial Transposition of Lateral Rectus for Pediatric Complete Oculomotor Palsy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang KX,
Varma H,
Cao Y,
Shah VS</span><br />
<span class="medgenPMjournal">J Neuroophthalmol</span>
2023 Jun 1;43(2):254-260.
Epub 2022 Nov 7
doi: 10.1097/WNO.0000000000001731.
<span class="bold">PMID: </span><a href="/pubmed/36342135" target="_blank">36342135</a><a href="/pmc/articles/PMC10166200" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31751614">Primary and Recurrent Growing Teratoma Syndrome in Central Nervous System Nongerminomatous Germ Cell Tumors: Case Series and Review of the Literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tsuyuguchi S,
Sugiyama K,
Kinoshita Y,
Kolakshyapati M,
Takayasu T,
Usui S,
Takano M,
Yonezawa U,
Taguchi A,
Amatya VJ,
Takeshima Y,
Kurisu K,
Yamasaki F</span><br />
<span class="medgenPMjournal">World Neurosurg</span>
2020 Feb;134:e360-e371.
Epub 2019 Nov 18
doi: 10.1016/j.wneu.2019.10.074.
<span class="bold">PMID: </span><a href="/pubmed/31751614" target="_blank">31751614</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29067503">Clinical features, radiologic findings, and treatment of pediatric germ cell tumors involving the basal ganglia and thalamus: a retrospective series of 15 cases at a single center.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang M,
Zhou P,
Zhang S,
Liu X,
Lv L,
Wang Z,
Ye F,
Ju Y,
Jiang S</span><br />
<span class="medgenPMjournal">Childs Nerv Syst</span>
2018 Mar;34(3):423-430.
Epub 2017 Oct 24
doi: 10.1007/s00381-017-3632-6.
<span class="bold">PMID: </span><a href="/pubmed/29067503" target="_blank">29067503</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25413617">Apparent diffusion coefficient of intracranial germ cell tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ogiwara H,
Tsutsumi Y,
Matsuoka K,
Kiyotani C,
Terashima K,
Morota N</span><br />
<span class="medgenPMjournal">J Neurooncol</span>
2015 Feb;121(3):565-71.
Epub 2014 Nov 21
doi: 10.1007/s11060-014-1668-y.
<span class="bold">PMID: </span><a href="/pubmed/25413617" target="_blank">25413617</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10582672">Treatment of intracranial nongerminomatous germ-cell tumor by high-dose chemotherapy and autologous stem-cell rescue.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tada T,
Takizawa T,
Nakazato F,
Kobayashi S,
Koike K,
Oguchi M,
Ishii E,
Amano Y</span><br />
<span class="medgenPMjournal">J Neurooncol</span>
1999 Aug;44(1):71-6.
doi: 10.1023/a:1006395719917.
<span class="bold">PMID: </span><a href="/pubmed/10582672" target="_blank">10582672</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12)</a></div></div>
</div>
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<div class="nl"><a target="_blank" href="/pubmed/33753128">Primary intracranial pure endodermal sinus tumor: A retrospective series of 6 cases in a single center and a systematic review of overall survival.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Raynald,
Yang H,
Zhang X,
Ma'ruf L,
Li C,
Jiang T</span><br />
<span class="medgenPMjournal">Neurochirurgie</span>
2021 Nov;67(6):587-598.
Epub 2021 Mar 19
doi: 10.1016/j.neuchi.2021.02.014.
<span class="bold">PMID: </span><a href="/pubmed/33753128" target="_blank">33753128</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Nongerminomatous%20germ%20cell%20tumor%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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