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<meta name="keywords" content="C0342543, central precocious puberties, central precocious puberty, cpp, disease or syndrome, gonadotropin-dependant precocious puberty, gonadotropin-dependent precocious puberty, precocious puberties, central, precocious puberty, central, puberties, central precocious, puberty, central precocious, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=90985
|
||
ConceptID=C0342543
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Central precocious puberty</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>90985</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0342543</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Central Precocious Puberties; Central Precocious Puberty; Precocious Puberties, Central; Precocious Puberty, Central; Puberties, Central Precocious; Puberty, Central Precocious</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Central precocious puberty (237816004)</td></tr>
|
||
<tr><td>Modes of inheritance:</td>
|
||
<td>
|
||
<div class="divPopper rprt" id="moi_141047"><div><strong>Autosomal dominant inheritance</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>141047</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0443147</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Intellectual Product</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in heterozygotes. In the context of medical genetics, an autosomal dominant disorder is caused when a single copy of the mutant allele is present. Males and females are affected equally, and can both transmit the disorder with a risk of 50% for each child of inheriting the mutant allele.</div></div>
|
||
<div class="divPopper rprt" id="moi_988794"><div><strong>Not genetically inherited</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>988794</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms that cannot be identified in NLM's Unified Medical Language system (UMLS) Click for more information.">CN307044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Source: Orphanet</div>
|
||
<div class="spaceAbove">clinical entity without genetic inheritance.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/988794">This record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_141047" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant inheritance</a><span> (Orphanet)</span></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#moi_988794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Not genetically inherited</a><span> (Orphanet)</span></div></td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0019165" target="_blank">MONDO:0019165</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span> Phenotypic series:</td>
|
||
<td><a href="https://omim.org/phenotypicSeries/PS176400" target="_blank">PS176400</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=759">ORPHA759</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys). [from <a title="Orphanet Rare Disease Ontology (ORDO)" href="http://www.orphadata.org/cgi-bin/inc/ordo_orphanet.inc.php" class="defSource" target="_blank">ORDO</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0342543[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=90985">C</a></span><span class="chiclet Rcolor round" title="Research test"><a target="_blank" href="/gtr/tests/?term=C0342543[DISCUI]&test_type=Research&redirect=true" ref="ncbi_uid=90985">R</a></span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=90985" ref="ncbi_uid=90985">V</a></span></span><span class="TLline">Central precocious puberty</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/893021" ref="tree=MeSH" title="MedGen record for Abnormality of the endocrine system">Abnormality of the endocrine system</a></span><ul><li><span class="TLline"><a href="/medgen/870247" ref="tree=MeSH" title="MedGen record for Puberty and gonadal disorders">Puberty and gonadal disorders</a></span><ul><li><span class="TLline"><a href="/medgen/868001" ref="tree=MeSH" title="MedGen record for Early onset of sexual maturation">Early onset of sexual maturation</a></span><ul><li><span class="TLline"><a href="/medgen/18752" ref="tree=MeSH" title="MedGen record for Precocious puberty">Precocious puberty</a></span><ul><li><span class="matched_ds">Central precocious puberty</span><ul><li><span class="TLline"><a href="/medgen/575094" ref="tree=MeSH" title="MedGen record for Idiopathic central precocious puberty">Idiopathic central precocious puberty</a></span></li><li><span class="TLline"><a href="/medgen/797791" ref="tree=MeSH" title="MedGen record for Secondary central precocious puberty">Secondary central precocious puberty</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=8674&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Central precocious puberty</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30086862">Central precocious puberty: From genetics to treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aguirre RS,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Endocrinol Metab</span>
|
||
2018 Aug;32(4):343-354.
|
||
Epub 2018 May 26
|
||
doi: 10.1016/j.beem.2018.05.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30086862" target="_blank">30086862</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26852255">Causes, diagnosis, and treatment of central precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latronico AC,
|
||
Brito VN,
|
||
Carel JC</span><br />
|
||
<span class="medgenPMjournal">Lancet Diabetes Endocrinol</span>
|
||
2016 Mar;4(3):265-274.
|
||
Epub 2016 Feb 4
|
||
doi: 10.1016/S2213-8587(15)00380-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26852255" target="_blank">26852255</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22central%20precocious%20puberty%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (187)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36916130">Approach to the Patient: Central Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kilberg MJ,
|
||
Vogiatzi MG</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2023 Jul 14;108(8):2115-2123.
|
||
doi: 10.1210/clinem/dgad081.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36916130" target="_blank">36916130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34784914">Obesity is a risk factor for central precocious puberty: a case-control study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu G,
|
||
Guo J,
|
||
Zhang X,
|
||
Lu Y,
|
||
Miao J,
|
||
Xue H</span><br />
|
||
<span class="medgenPMjournal">BMC Pediatr</span>
|
||
2021 Nov 16;21(1):509.
|
||
doi: 10.1186/s12887-021-02936-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34784914" target="_blank">34784914</a><a href="/pmc/articles/PMC8594221" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33325409">Central precocious puberty in spina bifida children: Guidelines for the care of people with spina bifida.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Almutlaq N,
|
||
O'Neil J,
|
||
Fuqua JS</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Rehabil Med</span>
|
||
2020;13(4):557-563.
|
||
doi: 10.3233/PRM-200728.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33325409" target="_blank">33325409</a><a href="/pmc/articles/PMC7838954" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19332438">Consensus statement on the use of gonadotropin-releasing hormone analogs in children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carel JC,
|
||
Eugster EA,
|
||
Rogol A,
|
||
Ghizzoni L,
|
||
Palmert MR;
|
||
ESPE-LWPES GnRH Analogs Consensus Conference Group,
|
||
Antoniazzi F,
|
||
Berenbaum S,
|
||
Bourguignon JP,
|
||
Chrousos GP,
|
||
Coste J,
|
||
Deal S,
|
||
de Vries L,
|
||
Foster C,
|
||
Heger S,
|
||
Holland J,
|
||
Jahnukainen K,
|
||
Juul A,
|
||
Kaplowitz P,
|
||
Lahlou N,
|
||
Lee MM,
|
||
Lee P,
|
||
Merke DP,
|
||
Neely EK,
|
||
Oostdijk W,
|
||
Phillip M,
|
||
Rosenfield RL,
|
||
Shulman D,
|
||
Styne D,
|
||
Tauber M,
|
||
Wit JM</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2009 Apr;123(4):e752-62.
|
||
Epub 2009 Mar 30
|
||
doi: 10.1542/peds.2008-1783.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19332438" target="_blank">19332438</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (608)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37074536">Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Banerjee S,
|
||
Bajpai A</span><br />
|
||
<span class="medgenPMjournal">Indian J Pediatr</span>
|
||
2023 Jun;90(6):582-589.
|
||
Epub 2023 Apr 19
|
||
doi: 10.1007/s12098-023-04554-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37074536" target="_blank">37074536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33745030">Diagnosis and management of precocious sexual maturation: an updated review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheuiche AV,
|
||
da Silveira LG,
|
||
de Paula LCP,
|
||
Lucena IRS,
|
||
Silveiro SP</span><br />
|
||
<span class="medgenPMjournal">Eur J Pediatr</span>
|
||
2021 Oct;180(10):3073-3087.
|
||
Epub 2021 Mar 21
|
||
doi: 10.1007/s00431-021-04022-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33745030" target="_blank">33745030</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30086862">Central precocious puberty: From genetics to treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Aguirre RS,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Endocrinol Metab</span>
|
||
2018 Aug;32(4):343-354.
|
||
Epub 2018 May 26
|
||
doi: 10.1016/j.beem.2018.05.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30086862" target="_blank">30086862</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26852255">Causes, diagnosis, and treatment of central precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Latronico AC,
|
||
Brito VN,
|
||
Carel JC</span><br />
|
||
<span class="medgenPMjournal">Lancet Diabetes Endocrinol</span>
|
||
2016 Mar;4(3):265-274.
|
||
Epub 2016 Feb 4
|
||
doi: 10.1016/S2213-8587(15)00380-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26852255" target="_blank">26852255</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (609)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37973253">Central precocious puberty: a review of diagnosis, treatment, and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zevin EL,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Lancet Child Adolesc Health</span>
|
||
2023 Dec;7(12):886-896.
|
||
doi: 10.1016/S2352-4642(23)00237-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37973253" target="_blank">37973253</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37074536">Precocious Puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Banerjee S,
|
||
Bajpai A</span><br />
|
||
<span class="medgenPMjournal">Indian J Pediatr</span>
|
||
2023 Jun;90(6):582-589.
|
||
Epub 2023 Apr 19
|
||
doi: 10.1007/s12098-023-04554-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37074536" target="_blank">37074536</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34975773">Should Skeletal Maturation Be Manipulated for Extra Height Gain?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wit JM</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2021;12:812196.
|
||
Epub 2021 Dec 16
|
||
doi: 10.3389/fendo.2021.812196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34975773" target="_blank">34975773</a><a href="/pmc/articles/PMC8716689" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24617179">Hypothalamic hamartoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Topff L,
|
||
Gelin G</span><br />
|
||
<span class="medgenPMjournal">JBR-BTR</span>
|
||
2013 Nov-Dec;96(6):362-4.
|
||
doi: 10.5334/jbr-btr.461.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24617179" target="_blank">24617179</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17970643">Leuprolide acetate: a drug of diverse clinical applications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson AC,
|
||
Meethal SV,
|
||
Bowen RL,
|
||
Atwood CS</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
|
||
2007 Nov;16(11):1851-63.
|
||
doi: 10.1517/13543784.16.11.1851.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17970643" target="_blank">17970643</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (495)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38677866">Treatment of Central Precocious Puberty with a Focus on Girls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bangalore Krishna K,
|
||
Klein KO,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Endocrinol Metab Clin North Am</span>
|
||
2024 Jun;53(2):229-238.
|
||
Epub 2024 Feb 18
|
||
doi: 10.1016/j.ecl.2024.01.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38677866" target="_blank">38677866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36339428">Precocious puberty and microbiota: The role of the sex hormone-gut microbiome axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Calcaterra V,
|
||
Rossi V,
|
||
Massini G,
|
||
Regalbuto C,
|
||
Hruby C,
|
||
Panelli S,
|
||
Bandi C,
|
||
Zuccotti G</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2022;13:1000919.
|
||
Epub 2022 Oct 21
|
||
doi: 10.3389/fendo.2022.1000919.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36339428" target="_blank">36339428</a><a href="/pmc/articles/PMC9634744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34975773">Should Skeletal Maturation Be Manipulated for Extra Height Gain?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wit JM</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2021;12:812196.
|
||
Epub 2021 Dec 16
|
||
doi: 10.3389/fendo.2021.812196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34975773" target="_blank">34975773</a><a href="/pmc/articles/PMC8716689" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32591066">Update on Precocious Puberty: Who Should Be Treated?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kaplowitz PB</span><br />
|
||
<span class="medgenPMjournal">Adv Pediatr</span>
|
||
2020 Aug;67:93-104.
|
||
Epub 2020 May 26
|
||
doi: 10.1016/j.yapd.2020.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32591066" target="_blank">32591066</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29323691">Premature Thelarche.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khokhar A,
|
||
Mojica A</span><br />
|
||
<span class="medgenPMjournal">Pediatr Ann</span>
|
||
2018 Jan 1;47(1):e12-e15.
|
||
doi: 10.3928/19382359-20171214-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29323691" target="_blank">29323691</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (398)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38677866">Treatment of Central Precocious Puberty with a Focus on Girls.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bangalore Krishna K,
|
||
Klein KO,
|
||
Eugster EA</span><br />
|
||
<span class="medgenPMjournal">Endocrinol Metab Clin North Am</span>
|
||
2024 Jun;53(2):229-238.
|
||
Epub 2024 Feb 18
|
||
doi: 10.1016/j.ecl.2024.01.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38677866" target="_blank">38677866</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37496240">Premature Thelarche: An Updated Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leung AKC,
|
||
Lam JM,
|
||
Hon KL</span><br />
|
||
<span class="medgenPMjournal">Curr Pediatr Rev</span>
|
||
2024;20(4):500-509.
|
||
doi: 10.2174/1573396320666230726110658.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37496240" target="_blank">37496240</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36339428">Precocious puberty and microbiota: The role of the sex hormone-gut microbiome axis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Calcaterra V,
|
||
Rossi V,
|
||
Massini G,
|
||
Regalbuto C,
|
||
Hruby C,
|
||
Panelli S,
|
||
Bandi C,
|
||
Zuccotti G</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2022;13:1000919.
|
||
Epub 2022 Oct 21
|
||
doi: 10.3389/fendo.2022.1000919.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36339428" target="_blank">36339428</a><a href="/pmc/articles/PMC9634744" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34975773">Should Skeletal Maturation Be Manipulated for Extra Height Gain?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wit JM</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2021;12:812196.
|
||
Epub 2021 Dec 16
|
||
doi: 10.3389/fendo.2021.812196.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34975773" target="_blank">34975773</a><a href="/pmc/articles/PMC8716689" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17970643">Leuprolide acetate: a drug of diverse clinical applications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson AC,
|
||
Meethal SV,
|
||
Bowen RL,
|
||
Atwood CS</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
|
||
2007 Nov;16(11):1851-63.
|
||
doi: 10.1517/13543784.16.11.1851.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17970643" target="_blank">17970643</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (509)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39420314">Comparison of central precocious puberty frequency before and during COVID-19: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang J,
|
||
Xu J,
|
||
Tang X,
|
||
Wu R</span><br />
|
||
<span class="medgenPMjournal">BMC Endocr Disord</span>
|
||
2024 Oct 17;24(1):219.
|
||
doi: 10.1186/s12902-024-01749-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39420314" target="_blank">39420314</a><a href="/pmc/articles/PMC11484383" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38116317">An updated meta-analysis of the relationship between vitamin D levels and precocious puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cheng H,
|
||
Chen D,
|
||
Gao H</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2023;14:1298374.
|
||
Epub 2023 Dec 5
|
||
doi: 10.3389/fendo.2023.1298374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38116317" target="_blank">38116317</a><a href="/pmc/articles/PMC10728595" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33887744">Kisspeptin Levels in Girls with Precocious Puberty: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cintra RG,
|
||
Wajnsztejn R,
|
||
Trevisan CM,
|
||
Zaia V,
|
||
Laganà AS,
|
||
Bianco B,
|
||
Montagna E</span><br />
|
||
<span class="medgenPMjournal">Horm Res Paediatr</span>
|
||
2020;93(11-12):589-598.
|
||
Epub 2021 Apr 22
|
||
doi: 10.1159/000515660.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33887744" target="_blank">33887744</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32654496">Herbal Medicine for Idiopathic Central Precocious Puberty: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee YB,
|
||
Lee JA,
|
||
Lee HL</span><br />
|
||
<span class="medgenPMjournal">J Altern Complement Med</span>
|
||
2020 Nov;26(11):976-999.
|
||
Epub 2020 Jul 10
|
||
doi: 10.1089/acm.2019.0312.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32654496" target="_blank">32654496</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29902155">Prevalence of cranial MRI findings in girls with central precocious puberty: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cantas-Orsdemir S,
|
||
Garb JL,
|
||
Allen HF</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Endocrinol Metab</span>
|
||
2018 Jul 26;31(7):701-710.
|
||
doi: 10.1515/jpem-2018-0052.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29902155" target="_blank">29902155</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Central%20precocious%20puberty%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0342543%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0342543%5bDISCUI%5d&test_type=Research" target="_blank">Research (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0342543%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0342543%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (1)</a></li>
|
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0342543%5bDISCUI%5d" target="_blank">See all (2)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/phenotypicSeries/PS176400" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=759" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Central%20precocious%20puberty" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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</div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22central%20precocious%20puberty%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Central%20precocious%20puberty%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet mgSection" id="ID_116">
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||
<div class="portlet_content ln"><ul><li><a href="http://www.diseaseinfosearch.org/Central+precocious+puberty/7933" target="_blank">Genetic Alliance</a></li><li><a href="https://www.malacards.org/card/precocious_puberty_central_1" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Central%20precocious%20puberty" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/16546/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
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|
||
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|
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<li>
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<a href="/pubmed/clinical?term=Central%20precocious%20puberty" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Central%20precocious%20puberty%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<h3>Related information</h3>
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<li class="brieflinkpopper">
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||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=90985" ref="log$=recordlinks">ClinVar</a>
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<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0342543[DISCUI]" ref="log$=recordlinks">GTR</a>
|
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<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
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|
||
<li class="brieflinkpopper">
|
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0342543[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
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<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
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</li>
|
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0342543[DISCUI]&test_type=Research" ref="log$=recordlinks">GTR(Research)</a>
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<div class="brieflinkpop offscreen_noflow">Research tests in GTR</div>
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<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=90985" ref="log$=recordlinks">MeSH</a>
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<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=90985" ref="log$=recordlinks">PMC Articles</a>
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<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
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<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=90985" ref="log$=recordlinks">PubMed</a>
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<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
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<h3>Recent activity</h3>
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
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Turn On
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d13d23f4a390645ebab565">Central precocious puberty</a>
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<div class="ralinkpop offscreen_noflow">Central precocious puberty<div class="brieflinkpopdesc"></div></div>
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<div class="tertiary">MedGen</div>
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