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<meta name="keywords" content="C0233763, hallucination, visual, hallucinations, visual, seeing things, sign or symptom, visual hallucination, visual hallucinations, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Visual perception in the absence of a visual stimulus." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Visual hallucination (Concept Id: C0233763)
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<!--
UID=66688
ConceptID=C0233763
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Visual hallucination</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66688</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0233763</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Sign or Symptom</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Visual hallucinations</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Seeing things (64269007); Visual hallucinations (64269007)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002367">HP:0002367</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Visual perception in the absence of a visual stimulus. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0233763[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=66688">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=66688" ref="ncbi_uid=66688">V</a></span></span><span class="TLline">Visual hallucination</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/474891" ref="tree=MeSH" title="MedGen record for Congenital Systemic Disorder">Congenital Systemic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/105425" ref="tree=MeSH" title="MedGen record for Abnormality of the nervous system">Abnormality of the nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/868417" ref="tree=MeSH" title="MedGen record for Abnormal nervous system physiology">Abnormal nervous system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868938" ref="tree=MeSH" title="MedGen record for Abnormality of mental function">Abnormality of mental function</a></span><ul><li><span class="TLline"><a href="/medgen/1853246" ref="tree=MeSH" title="MedGen record for Abnormal experience of reality">Abnormal experience of reality</a></span><ul><li><span class="TLline"><a href="/medgen/6709" ref="tree=MeSH" title="MedGen record for Hallucinations">Hallucinations</a></span><ul><li><span class="matched_ds">Visual hallucination</span><ul><li><span class="TLline"><a href="/medgen/870530" ref="tree=MeSH" title="MedGen record for Vivid hallucination">Vivid hallucination</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_199874"><div><strong>Lewy body dementia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>199874</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0752347</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Dementia with Lewy bodies (DLB) is a neurodegenerative disorder clinically characterized by dementia and parkinsonism, often with fluctuating cognitive function, visual hallucinations, falls, syncopal episodes, and sensitivity to neuroleptic medication. Pathologically, Lewy bodies are present in a pattern more widespread than usually observed in Parkinson disease (see PD; 168600). Alzheimer disease (AD; 104300)-associated pathology and spongiform changes may also be seen (McKeith et al., 1996; Mizutani, 2000; McKeith et al., 2005).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/199874">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_331388"><div><strong>Migraine, familial hemiplegic, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331388</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1832884</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Familial hemiplegic migraine (FHM) falls within the category of migraine with aura. In migraine with aura (including FHM) the neurologic symptoms of aura are unequivocally localizable to the cerebral cortex or brain stem and include visual disturbance (most common), sensory loss (e.g., numbness or paresthesias of the face or an extremity), and dysphasia (difficulty with speech). FHM must include motor involvement, such as hemiparesis (weakness of an extremity). Hemiparesis occurs with at least one other symptom during FHM aura. Neurologic deficits with FHM attacks can be prolonged for hours to days and may outlast the associated migrainous headache. FHM is often earlier in onset than typical migraine, frequently beginning in the first or second decade; the frequency of attacks tends to decrease with age. Approximately 40%-50% of families with CACNA1A-FHM have cerebellar signs ranging from nystagmus to progressive, usually late-onset mild ataxia.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/331388">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_320287"><div><strong>Ceroid lipofuscinosis, neuronal, 4 (Kufs type)</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>320287</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1834207</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Neuronal ceroid lipofuscinosis-4 (CLN4) is an autosomal dominant neurodegenerative disorder characterized by onset of symptoms in adulthood. It belongs to a group of progressive neurodegenerative diseases characterized by accumulation of intracellular autofluorescent lipopigment storage material in the brain and other tissues. Several different forms have been described according to age of onset (see, e.g., CLN3, 204200). Individuals with the adult form, sometimes referred to as Kufs disease, develop psychiatric manifestations, seizures, cerebellar ataxia, and cognitive decline. Retinal degeneration is usually not present (summary by Benitez et al., 2011 and Velinov et al., 2012).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of CLN, see CLN1 (256730).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/320287">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_862085"><div><strong>Bilateral parasagittal parieto-occipital polymicrogyria</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>862085</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4013648</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Polymicrogyria is a condition characterized by abnormal development of the brain before birth. The surface of the brain normally has many ridges or folds, called gyri. In people with polymicrogyria, the brain develops too many folds, and the folds are unusually small. The name of this condition literally means too many (poly-) small (micro-) folds (-gyria) in the surface of the brain.\n\nPolymicrogyria can affect part of the brain or the whole brain. When the condition affects one side of the brain, researchers describe it as unilateral. When it affects both sides of the brain, it is described as bilateral. The signs and symptoms associated with polymicrogyria depend on how much of the brain, and which particular brain regions, are affected.\n\nResearchers have identified multiple forms of polymicrogyria. The mildest form is known as unilateral focal polymicrogyria. This form of the condition affects a relatively small area on one side of the brain. It may cause minor neurological problems, such as mild seizures that can be easily controlled with medication. Some people with unilateral focal polymicrogyria do not have any problems associated with the condition.\n\nPolymicrogyria most often occurs as an isolated feature, although it can occur with other brain abnormalities. It is also a feature of several genetic syndromes characterized by intellectual disability and multiple birth defects. These include 22q11.2 deletion syndrome, Adams-Oliver syndrome, Aicardi syndrome, Galloway-Mowat syndrome, Joubert syndrome, and Zellweger spectrum disorder.\n\nBilateral forms of polymicrogyria tend to cause more severe neurological problems. Signs and symptoms of these conditions can include recurrent seizures (epilepsy), delayed development, crossed eyes, problems with speech and swallowing, and muscle weakness or paralysis. The most severe form of the disorder, bilateral generalized polymicrogyria, affects the entire brain. This condition causes severe intellectual disability, problems with movement, and seizures that are difficult or impossible to control with medication.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/862085">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1794137"><div><strong>Ceroid lipofuscinosis, neuronal, 6B (Kufs type)</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794137</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5561927</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Neuronal ceroid lipofuscinosis-6B (CLN6B) is an autosomal recessive form of 'Kufs disease,' which refers in general to adult-onset neuronal ceroid lipofuscinosis without retinal involvement. CLN6B is a neurodegenerative disorder with a mean onset of symptoms at around age 28 years, although onset in the teens and later adulthood may also occur. Patients typically present with progressive myoclonus epilepsy, ataxia, loss of motor function, dysarthria, progressive dementia, and progressive cerebral and cerebellar atrophy on brain imaging. Ultrastructural examination typically shows fingerprint profiles and granular osmiophilic deposits in some tissues, including brain samples (summary by Arsov et al., 2011 and Berkovic et al., 2019). However, pathologic findings in peripheral tissues in adults is not as accurate for diagnosis as it is in children with the disease (Cherian et al., 2021).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of CLN, see CLN1 (256730).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1794137">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1844054"><div><strong>Myoclonic epilepsy of Lafora 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1844054</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5848203</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Progressive myoclonus epilepsy, Lafora type (also known as Lafora disease) is characterized by focal occipital seizures presenting as transient blindness or visual hallucinations and fragmentary, symmetric, or generalized myoclonus occurring in previously healthy individuals. Typical age of onset is eight to 19 years (peak: age14-16 years). Generalized tonic-clonic seizures, atypical absence seizures, atonic seizures, and focal seizures with impaired awareness may also occur. The course of the disease is characterized by increasing frequency and intractability of seizures. Status epilepticus with any of the seizure types is common. Cognitive decline becomes apparent at or soon after the onset of seizures. Dysarthria and ataxia appear early, while spasticity appears late. Emotional disturbances and confusion are common in the early stages of the disease and are followed by dementia. Most affected individuals die within ten years of onset, usually from status epilepticus or from complications related to neurologic degeneration.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1844054">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_862085" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bilateral parasagittal parieto-occipital polymicrogyria</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_320287" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ceroid lipofuscinosis, neuronal, 4 (Kufs type)</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794137" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ceroid lipofuscinosis, neuronal, 6B (Kufs type)</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_199874" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lewy body dementia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331388" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Migraine, familial hemiplegic, 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1844054" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myoclonic epilepsy of Lafora 1</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37737161">Clinical presentations and treatment outcomes of Hashimoto encephalopathy at Siriraj Hospital - Thailand's largest national tertiary referral center.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dumrikarnlert C,
Thakolwiboon S,
Senanarong V</span><br />
<span class="medgenPMjournal">BMC Neurol</span>
2023 Sep 22;23(1):334.
doi: 10.1186/s12883-023-03305-4.
<span class="bold">PMID: </span><a href="/pubmed/37737161" target="_blank">37737161</a><a href="/pmc/articles/PMC10514970" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33021110">Pharmacological management of dementia with Lewy bodies with a focus on zonisamide for treating parkinsonism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Panza F,
Lozupone M,
Watling M,
Imbimbo BP</span><br />
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
2021 Feb;22(3):325-337.
Epub 2020 Oct 6
doi: 10.1080/14656566.2020.1828350.
<span class="bold">PMID: </span><a href="/pubmed/33021110" target="_blank">33021110</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30398127">Management of visual hallucinations in dementia and Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Swann P,
O'Brien JT</span><br />
<span class="medgenPMjournal">Int Psychogeriatr</span>
2019 Jun;31(6):815-836.
Epub 2018 Nov 6
doi: 10.1017/S1041610218001400.
<span class="bold">PMID: </span><a href="/pubmed/30398127" target="_blank">30398127</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22visual%20hallucination%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37141962">Understanding visual hallucinations: A new synthesis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Collerton D,
Barnes J,
Diederich NJ,
Dudley R,
Ffytche D,
Friston K,
Goetz CG,
Goldman JG,
Jardri R,
Kulisevsky J,
Lewis SJG,
Nara S,
O'Callaghan C,
Onofrj M,
Pagonabarraga J,
Parr T,
Shine JM,
Stebbins G,
Taylor JP,
Tsuda I,
Weil RS</span><br />
<span class="medgenPMjournal">Neurosci Biobehav Rev</span>
2023 Jul;150:105208.
Epub 2023 May 2
doi: 10.1016/j.neubiorev.2023.105208.
<span class="bold">PMID: </span><a href="/pubmed/37141962" target="_blank">37141962</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33021110">Pharmacological management of dementia with Lewy bodies with a focus on zonisamide for treating parkinsonism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Panza F,
Lozupone M,
Watling M,
Imbimbo BP</span><br />
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
2021 Feb;22(3):325-337.
Epub 2020 Oct 6
doi: 10.1080/14656566.2020.1828350.
<span class="bold">PMID: </span><a href="/pubmed/33021110" target="_blank">33021110</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31530334">Modality-general and modality-specific processes in hallucinations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fernyhough C</span><br />
<span class="medgenPMjournal">Psychol Med</span>
2019 Dec;49(16):2639-2645.
Epub 2019 Sep 18
doi: 10.1017/S0033291719002496.
<span class="bold">PMID: </span><a href="/pubmed/31530334" target="_blank">31530334</a><a href="/pmc/articles/PMC6877466" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28802934">Psychosis in Parkinson's Disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ffytche DH,
Aarsland D</span><br />
<span class="medgenPMjournal">Int Rev Neurobiol</span>
2017;133:585-622.
Epub 2017 Jun 16
doi: 10.1016/bs.irn.2017.04.005.
<span class="bold">PMID: </span><a href="/pubmed/28802934" target="_blank">28802934</a></div>
<div class="nl"><a target="_blank" href="/pubmed/486593">A mathematical theory of visual hallucination patterns.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ermentrout GB,
Cowan JD</span><br />
<span class="medgenPMjournal">Biol Cybern</span>
1979 Oct;34(3):137-50.
doi: 10.1007/BF00336965.
<span class="bold">PMID: </span><a href="/pubmed/486593" target="_blank">486593</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (81)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37992107">BEAST ON HER SHOULDER: A RARE PRESENTATION OF PEDUNCULAR VISUAL HALLUCINATION IN A CASE OF CRANIOPHARYNGIOMA.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shekhar S,
Ranjan R,
Mallik S,
Aggarwal K,
Kumar P</span><br />
<span class="medgenPMjournal">Psychiatr Danub</span>
2023 Winter;35(4):595-597.
doi: 10.24869/psyd.2023.595.
<span class="bold">PMID: </span><a href="/pubmed/37992107" target="_blank">37992107</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33021110">Pharmacological management of dementia with Lewy bodies with a focus on zonisamide for treating parkinsonism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Panza F,
Lozupone M,
Watling M,
Imbimbo BP</span><br />
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
2021 Feb;22(3):325-337.
Epub 2020 Oct 6
doi: 10.1080/14656566.2020.1828350.
<span class="bold">PMID: </span><a href="/pubmed/33021110" target="_blank">33021110</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31530334">Modality-general and modality-specific processes in hallucinations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fernyhough C</span><br />
<span class="medgenPMjournal">Psychol Med</span>
2019 Dec;49(16):2639-2645.
Epub 2019 Sep 18
doi: 10.1017/S0033291719002496.
<span class="bold">PMID: </span><a href="/pubmed/31530334" target="_blank">31530334</a><a href="/pmc/articles/PMC6877466" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31446216">Visual hallucinations in psychosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">van Ommen MM,
van Laar T,
Cornelissen FW,
Bruggeman R</span><br />
<span class="medgenPMjournal">Psychiatry Res</span>
2019 Oct;280:112517.
Epub 2019 Aug 10
doi: 10.1016/j.psychres.2019.112517.
<span class="bold">PMID: </span><a href="/pubmed/31446216" target="_blank">31446216</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6658921">Clinicopathological study of pontine hemorrhage.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nakajima K</span><br />
<span class="medgenPMjournal">Stroke</span>
1983 Jul-Aug;14(4):485-93.
doi: 10.1161/01.str.14.4.485.
<span class="bold">PMID: </span><a href="/pubmed/6658921" target="_blank">6658921</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (96)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/37922514">The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blackman G,
Dadwal AK,
Teixeira-Dias M,
Ffytche D</span><br />
<span class="medgenPMjournal">Cogn Neuropsychiatry</span>
2023 Nov;28(6):391-405.
Epub 2023 Nov 30
doi: 10.1080/13546805.2023.2266872.
<span class="bold">PMID: </span><a href="/pubmed/37922514" target="_blank">37922514</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34515368">Isotretinoin-induced visual hallucinations in a patient with acne vulgaris.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Demirci Saadet E</span><br />
<span class="medgenPMjournal">Pediatr Dermatol</span>
2021 Sep;38(5):1349-1350.
Epub 2021 Sep 13
doi: 10.1111/pde.14807.
<span class="bold">PMID: </span><a href="/pubmed/34515368" target="_blank">34515368</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33733898">Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Anupama BK,
Sampat P,
Gambhir HS</span><br />
<span class="medgenPMjournal">J Investig Med High Impact Case Rep</span>
2021 Jan-Dec;9:23247096211001659.
doi: 10.1177/23247096211001659.
<span class="bold">PMID: </span><a href="/pubmed/33733898" target="_blank">33733898</a><a href="/pmc/articles/PMC7983233" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33021110">Pharmacological management of dementia with Lewy bodies with a focus on zonisamide for treating parkinsonism.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Panza F,
Lozupone M,
Watling M,
Imbimbo BP</span><br />
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
2021 Feb;22(3):325-337.
Epub 2020 Oct 6
doi: 10.1080/14656566.2020.1828350.
<span class="bold">PMID: </span><a href="/pubmed/33021110" target="_blank">33021110</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31446216">Visual hallucinations in psychosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">van Ommen MM,
van Laar T,
Cornelissen FW,
Bruggeman R</span><br />
<span class="medgenPMjournal">Psychiatry Res</span>
2019 Oct;280:112517.
Epub 2019 Aug 10
doi: 10.1016/j.psychres.2019.112517.
<span class="bold">PMID: </span><a href="/pubmed/31446216" target="_blank">31446216</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (63)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37930972">Pareidolias are a function of visuoperceptual impairment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McCann E,
Lee S,
Coleman F,
O'Sullivan JD,
Nestor PJ</span><br />
<span class="medgenPMjournal">PLoS One</span>
2023;18(11):e0293942.
Epub 2023 Nov 6
doi: 10.1371/journal.pone.0293942.
<span class="bold">PMID: </span><a href="/pubmed/37930972" target="_blank">37930972</a><a href="/pmc/articles/PMC10627440" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37922514">The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blackman G,
Dadwal AK,
Teixeira-Dias M,
Ffytche D</span><br />
<span class="medgenPMjournal">Cogn Neuropsychiatry</span>
2023 Nov;28(6):391-405.
Epub 2023 Nov 30
doi: 10.1080/13546805.2023.2266872.
<span class="bold">PMID: </span><a href="/pubmed/37922514" target="_blank">37922514</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30566288">Conceptual definition in the metamorphosing Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maeda T,
Iwaoka K,
Terayama Y</span><br />
<span class="medgenPMjournal">Nihon Rinsho</span>
2017 Jan;75(1):9-13.
<span class="bold">PMID: </span><a href="/pubmed/30566288" target="_blank">30566288</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25162511">Experience in delirium: is it distressing?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Grover S,
Ghosh A,
Ghormode D</span><br />
<span class="medgenPMjournal">J Neuropsychiatry Clin Neurosci</span>
2015;27(2):139-46.
Epub 2014 Oct 31
doi: 10.1176/appi.neuropsych.13110329.
<span class="bold">PMID: </span><a href="/pubmed/25162511" target="_blank">25162511</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10712657">Does the migraine aura reflect cortical organization?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dahlem MA,
Engelmann R,
Löwel S,
Müller SC</span><br />
<span class="medgenPMjournal">Eur J Neurosci</span>
2000 Feb;12(2):767-70.
doi: 10.1046/j.1460-9568.2000.00995.x.
<span class="bold">PMID: </span><a href="/pubmed/10712657" target="_blank">10712657</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (48)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37922514">The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blackman G,
Dadwal AK,
Teixeira-Dias M,
Ffytche D</span><br />
<span class="medgenPMjournal">Cogn Neuropsychiatry</span>
2023 Nov;28(6):391-405.
Epub 2023 Nov 30
doi: 10.1080/13546805.2023.2266872.
<span class="bold">PMID: </span><a href="/pubmed/37922514" target="_blank">37922514</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31810425">Pareidolia-proneness, reality discrimination errors, and visual hallucination-like experiences in a non-clinical sample.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Smailes D,
Burdis E,
Gregoriou C,
Fenton B,
Dudley R</span><br />
<span class="medgenPMjournal">Cogn Neuropsychiatry</span>
2020 Mar;25(2):113-125.
Epub 2019 Dec 6
doi: 10.1080/13546805.2019.1700789.
<span class="bold">PMID: </span><a href="/pubmed/31810425" target="_blank">31810425</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10712657">Does the migraine aura reflect cortical organization?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dahlem MA,
Engelmann R,
Löwel S,
Müller SC</span><br />
<span class="medgenPMjournal">Eur J Neurosci</span>
2000 Feb;12(2):767-70.
doi: 10.1046/j.1460-9568.2000.00995.x.
<span class="bold">PMID: </span><a href="/pubmed/10712657" target="_blank">10712657</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1537966">Hypnosis, reporting bias, and suggested negative hallucinations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Spanos NP,
Burgess CA,
Cross PA,
MacLeod G</span><br />
<span class="medgenPMjournal">J Abnorm Psychol</span>
1992 Feb;101(1):192-9.
doi: 10.1037//0021-843x.101.1.192.
<span class="bold">PMID: </span><a href="/pubmed/1537966" target="_blank">1537966</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6658921">Clinicopathological study of pontine hemorrhage.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nakajima K</span><br />
<span class="medgenPMjournal">Stroke</span>
1983 Jul-Aug;14(4):485-93.
doi: 10.1161/01.str.14.4.485.
<span class="bold">PMID: </span><a href="/pubmed/6658921" target="_blank">6658921</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (59)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/37922514">The association between visual hallucinations and secondary psychosis: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Blackman G,
Dadwal AK,
Teixeira-Dias M,
Ffytche D</span><br />
<span class="medgenPMjournal">Cogn Neuropsychiatry</span>
2023 Nov;28(6):391-405.
Epub 2023 Nov 30
doi: 10.1080/13546805.2023.2266872.
<span class="bold">PMID: </span><a href="/pubmed/37922514" target="_blank">37922514</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30474581">Auditory and visual hallucination prevalence in Parkinson's disease and dementia with Lewy bodies: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Eversfield CL,
Orton LD</span><br />
<span class="medgenPMjournal">Psychol Med</span>
2019 Oct;49(14):2342-2353.
Epub 2018 Nov 26
doi: 10.1017/S0033291718003161.
<span class="bold">PMID: </span><a href="/pubmed/30474581" target="_blank">30474581</a><a href="/pmc/articles/PMC6763539" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30398127">Management of visual hallucinations in dementia and Parkinson's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Swann P,
O'Brien JT</span><br />
<span class="medgenPMjournal">Int Psychogeriatr</span>
2019 Jun;31(6):815-836.
Epub 2018 Nov 6
doi: 10.1017/S1041610218001400.
<span class="bold">PMID: </span><a href="/pubmed/30398127" target="_blank">30398127</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24332912">MIBG myocardial scintigraphy in pre-motor Parkinson's disease: a review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sakakibara R,
Tateno F,
Kishi M,
Tsuyusaki Y,
Terada H,
Inaoka T</span><br />
<span class="medgenPMjournal">Parkinsonism Relat Disord</span>
2014 Mar;20(3):267-73.
Epub 2013 Nov 21
doi: 10.1016/j.parkreldis.2013.11.001.
<span class="bold">PMID: </span><a href="/pubmed/24332912" target="_blank">24332912</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Visual%20hallucination%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0233763%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (9)</a></li>
<li><a href="/gtr/tests?term=C0233763%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (9)</a></li>
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