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<meta name="keywords" content="C0220761, dizygotic twinning, dizygotic twins, dizygous twinning, finding, twinning, dizygotic, twinning, dizygous, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="The development of two genetically distinct EMBRYOS in a single UTERUS at the same time, from two separate OVA fertilized by two separate SPERMATOZOA." /><meta name="robots" content="index,nofollow,noarchive" />
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|
||
<!--
|
||
UID=67400
|
||
ConceptID=C0220761
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Dizygotic twins</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>67400</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0220761</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>TWINNING, DIZYGOTIC</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/276400" target="_blank">276400</a></td></tr>
|
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">The development of two genetically distinct EMBRYOS in a single UTERUS at the same time, from two separate OVA fertilized by two separate SPERMATOZOA. [from <a title="Medical Subject Headings" href="http://www.nlm.nih.gov/pubs/factsheets/mesh.html" class="defSource" target="_blank">MeSH</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/25719307">Pharmacogenetics of drug oxidation via cytochrome P450 (CYP) in the populations of Denmark, Faroe Islands and Greenland.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brosen K</span><br />
|
||
<span class="medgenPMjournal">Drug Metab Pers Ther</span>
|
||
2015 Sep;30(3):147-63.
|
||
doi: 10.1515/dmdi-2014-0029.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25719307" target="_blank">25719307</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/150232">Prenatal diagnosis of Down syndrome in one of dizygotic twins.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Filkins K,
|
||
Kushnick T,
|
||
Diamond N,
|
||
Searle B,
|
||
Desposito F</span><br />
|
||
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
|
||
1978 Jul 1;131(5):584-5.
|
||
doi: 10.1016/0002-9378(78)90123-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/150232" target="_blank">150232</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1036394">The problem of genotype-environment correlation in the estimation of heritability from monozygotic and dizygotic twins.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jensen AR</span><br />
|
||
<span class="medgenPMjournal">Acta Genet Med Gemellol (Roma)</span>
|
||
1976;25:86-99.
|
||
doi: 10.1017/s000156600001391x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1036394" target="_blank">1036394</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22dizygotic%20twins%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (23)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38482746">Congenital Anomalies in Multiple Pregnancy: A Literature Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shin JE,
|
||
Ko HS,
|
||
Bae JY,
|
||
Seong WJ,
|
||
Ahn TG,
|
||
Han YJ,
|
||
Cho GJ,
|
||
Park IY</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol Surv</span>
|
||
2024 Mar;79(3):167-175.
|
||
doi: 10.1097/OGX.0000000000001251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38482746" target="_blank">38482746</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34127172">Monochorionic Dizygotic Twins Conceived Spontaneously Showed Chimerism in Karyotype and Blood Group Type.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yoshida A,
|
||
Kaji T,
|
||
Sogawa E,
|
||
Yonetani N,
|
||
Suga K,
|
||
Nakagawa R,
|
||
Iwasa T</span><br />
|
||
<span class="medgenPMjournal">Twin Res Hum Genet</span>
|
||
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35033205">Handedness in twins: meta-analyses.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Pfeifer LS,
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Schmitz J,
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Papadatou-Pastou M,
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Peterburs J,
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Paracchini S,
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<div class="nl"><a target="_blank" href="/pubmed/33556853">The heritability of insomnia: Systematic review and meta-analysis of twin studies.</a></div>
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Rubio-Aparicio M,
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||
Tang S,
|
||
Mol BW,
|
||
Zamora J,
|
||
Thilaganathan B,
|
||
Thangaratinam S;
|
||
Global Obstetrics Network (GONet) Collaboration</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2016 Sep 6;354:i4353.
|
||
doi: 10.1136/bmj.i4353.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27599496" target="_blank">27599496</a><a href="/pmc/articles/PMC5013231" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Dizygotic%20twins%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (32)</a></div></div>
|
||
</div>
|
||
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<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0220761%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (7)</a></li>
|
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<li><a href="/gtr/tests?term=C0220761%5bDISCUI%5d&filter=method%3A2%5F13" target="_blank">Linkage analysis (1)</a></li>
|
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<li><a href="/gtr/tests?term=C0220761%5bDISCUI%5d&filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
|
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<li><a href="/gtr/tests?term=C0220761%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (9)</a></li>
|
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<li><a href="/gtr/tests?term=C0220761%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (4)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0220761%5bDISCUI%5d" target="_blank">See all (14)</a></total></li>
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