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<meta name="keywords" content="C0041657, consciousness, loss of, fainting, finding, loss of consciousness, mental status, unconsciousness, passing out, state, unconscious, unconscious, unconscious state, unconscious states, unconsciousness, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Loss of alertness and orientation to place and time." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=52915
|
||
ConceptID=C0041657
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Loss of consciousness</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>52915</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0041657</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Consciousness, Loss of; Loss of Consciousness; State, Unconscious; Unconscious State; Unconscious States; Unconsciousness</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Loss of consciousness (419045004); Unconscious (418107008); Mental status, unconsciousness (418107008); Unconsciousness (418107008)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0007185">HP:0007185</a></td></tr>
|
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Loss of alertness and orientation to place and time. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_118">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Loss of consciousness</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/18017" ref="tree=MeSH" title="MedGen record for Neurologic Manifestations">Neurologic Manifestations</a></span><ul><li><span class="TLline"><a href="/medgen/105653" ref="tree=MeSH" title="MedGen record for Neurobehavioral Manifestations">Neurobehavioral Manifestations</a></span><ul><li><span class="TLline"><a href="/medgen/1099" ref="tree=MeSH" title="MedGen record for Consciousness Disorders">Consciousness Disorders</a></span><ul><li><span class="matched_ds">Loss of consciousness</span><ul><li><span class="TLline"><a href="/medgen/552579" ref="tree=MeSH" title="MedGen record for Blacking Out">Blacking Out</a></span></li><li><span class="TLline"><a href="/medgen/1054" ref="tree=MeSH" title="MedGen record for Coma">Coma</a></span><ul><li><span class="TLline"><a href="/medgen/646" ref="tree=MeSH" title="MedGen record for Brain Death">Brain Death</a></span></li><li><span class="TLline"><a href="/medgen/1646242" ref="tree=MeSH" title="MedGen record for Coma Greater than 24 Hours">Coma Greater than 24 Hours</a></span></li><li><span class="TLline"><a href="/medgen/5710" ref="tree=MeSH" title="MedGen record for Hypoglycemic coma">Hypoglycemic coma</a></span><ul><li><span class="TLline"><a href="/medgen/9496" ref="tree=MeSH" title="MedGen record for Insulin coma">Insulin coma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/140754" ref="tree=MeSH" title="MedGen record for Post-traumatic coma">Post-traumatic coma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/66947" ref="tree=MeSH" title="MedGen record for Persistent vegetative state">Persistent vegetative state</a></span></li><li><span class="TLline"><a href="/medgen/88446" ref="tree=MeSH" title="MedGen record for Stupor">Stupor</a></span></li><li><span class="TLline"><a href="/medgen/21443" ref="tree=MeSH" title="MedGen record for Syncope">Syncope</a></span><ul><li><span class="TLline"><a href="/medgen/1708567" ref="tree=MeSH" title="MedGen record for Arrhythmogenic Syncope">Arrhythmogenic Syncope</a></span></li><li><span class="TLline"><a href="/medgen/113141" ref="tree=MeSH" title="MedGen record for Carotid sinus syncope">Carotid sinus syncope</a></span></li><li><span class="TLline"><a href="/medgen/1712686" ref="tree=MeSH" title="MedGen record for Drug-induced Syncope">Drug-induced Syncope</a></span></li><li><span class="TLline"><a href="/medgen/65902" ref="tree=MeSH" title="MedGen record for Effort syncope">Effort syncope</a></span></li><li><span class="TLline"><a href="/medgen/1714363" ref="tree=MeSH" title="MedGen record for Faceplant">Faceplant</a></span></li><li><span class="TLline"><a href="/medgen/776676" ref="tree=MeSH" title="MedGen record for Orthostatic syncope">Orthostatic syncope</a></span></li><li><span class="TLline"><a href="/medgen/536371" ref="tree=MeSH" title="MedGen record for Psychogenic syncope">Psychogenic syncope</a></span></li><li><span class="TLline"><a href="/medgen/748921" ref="tree=MeSH" title="MedGen record for Reflex asystolic syncope">Reflex asystolic syncope</a></span></li><li><span class="TLline"><a href="/medgen/1718034" ref="tree=MeSH" title="MedGen record for Syncope due to Acquired Heart Lesion">Syncope due to Acquired Heart Lesion</a></span></li><li><span class="TLline"><a href="/medgen/1717259" ref="tree=MeSH" title="MedGen record for Syncope due to Congenital Heart Lesion">Syncope due to Congenital Heart Lesion</a></span></li><li><span class="TLline"><a href="/medgen/1709755" ref="tree=MeSH" title="MedGen record for Syncope due to Migraine">Syncope due to Migraine</a></span></li><li><span class="TLline"><a href="/medgen/1710535" ref="tree=MeSH" title="MedGen record for Syncope due to Pulmonary Hypertension">Syncope due to Pulmonary Hypertension</a></span></li><li><span class="TLline"><a href="/medgen/473896" ref="tree=MeSH" title="MedGen record for Syncope with High Risk Cardiac Characteristics">Syncope with High Risk Cardiac Characteristics</a></span></li><li><span class="TLline"><a href="/medgen/12060" ref="tree=MeSH" title="MedGen record for Vasovagal syncope">Vasovagal syncope</a></span><ul><li><span class="TLline"><a href="/medgen/1716300" ref="tree=MeSH" title="MedGen record for Cardioinhibitory Syncope">Cardioinhibitory Syncope</a></span></li><li><span class="TLline"><a href="/medgen/87408" ref="tree=MeSH" title="MedGen record for Situational syncope">Situational syncope</a></span></li><li><span class="TLline"><a href="/medgen/1720513" ref="tree=MeSH" title="MedGen record for Vasodepressor Syncope">Vasodepressor Syncope</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_82803"><div><strong>Inborn glycerol kinase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82803</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268418</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">NR0B1-related adrenal hypoplasia congenita includes both X-linked adrenal hypoplasia congenita (X-linked AHC) and Xp21 deletion (previously called complex glycerol kinase deficiency). X-linked AHC is characterized by primary adrenal insufficiency and/or hypogonadotropic hypogonadism (HH). Adrenal insufficiency is acute infantile onset (average age 3 weeks) in approximately 60% of affected males and childhood onset (ages 1-9 years) in approximately 40%. HH typically manifests in a male with adrenal insufficiency as delayed puberty (i.e., onset age >14 years) and less commonly as arrested puberty at about Tanner Stage 3. Rarely, X-linked AHC manifests initially in early adulthood as delayed-onset adrenal insufficiency, partial HH, and/or infertility. Heterozygous females very occasionally have manifestations of adrenal insufficiency or hypogonadotropic hypogonadism. Xp21 deletion includes deletion of NR0B1 (causing X-linked AHC) and GK (causing glycerol kinase deficiency), and in some cases deletion of DMD (causing Duchenne muscular dystrophy). Developmental delay has been reported in males with Xp21 deletion when the deletion extends proximally to include DMD or when larger deletions extend distally to include IL1RAPL1 and DMD.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82803">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_105400"><div><strong>Breath-holding Spells</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>105400</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0476287</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The diagnosis of severe breath-holding spells (BHS) in childhood is based on a distinctive and stereotyped sequence of clinical events beginning with a provocation resulting in crying or emotional upset that leads to a noiseless state of expiration accompanied by color change and ultimately loss of consciousness and postural tone (Lombroso and Lerman, 1967; DiMario, 1992). Two clinical types are recognized based on the child's coloration (cyanotic or pallid) during these events. Most children experience the cyanotic type, although some experience mixed types. BHS is an involuntary, nonvolitional, reflexic, nonepileptic paroxysmal phenomenon of childhood. The episodes occur during full expiration despite its misnomer. Autonomic dysregulation has been hypothesized as an underlying mechanism that results in loss of consciousness (Hunt, 1990; DiMario and Burleson, 1993; Dimario et al., 1998).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/105400">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_226944"><div><strong>Deficiency of beta-ureidopropionase</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>226944</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1291512</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Beta-ureidopropionase deficiency is a rare autosomal recessive inborn error of metabolism due to a defect in pyrimidine degradation. Less than 10 patients have been reported, and the phenotype can range from severe neurologic involvement with mental retardation and seizures to normal neurologic development (Yaplito-Lee et al., 2008).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/226944">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_347149"><div><strong>Osteodysplastic primordial dwarfism, type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347149</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1859452</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">RNU4atac-opathy encompasses the phenotypic spectrum of biallelic RNU4ATAC pathogenic variants, including the three historically designated clinical phenotypes microcephalic osteodysplastic primordial dwarfism type I/III (MOPDI), Roifman syndrome, and Lowry-Wood syndrome, as well as varying combinations of the disease features / system involvement that do not match specific defined phenotypes. Findings present in all affected individuals include growth restriction, microcephaly, skeletal dysplasia, and cognitive impairment. Less common but variable findings include brain anomalies, seizures, strokes, immunodeficiency, and cardiac anomalies, as well as ophthalmologic, skin, renal, gastrointestinal, hearing, and endocrine involvement.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/347149">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_355075"><div><strong>Neuronal intranuclear inclusion disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355075</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1863843</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neuronal intranuclear inclusion disease (NIID) is an autosomal dominant, slowly progressive neurodegenerative disorder characterized by a wide range of clinical manifestations, including pyramidal and extrapyramidal symptoms, cerebellar ataxia, cognitive decline and dementia, peripheral neuropathy, and autonomic dysfunction. The age at onset varies, but most individuals present as adults between about 30 and 70 years of age. Pathologic investigation shows eosinophilic intranuclear inclusions in almost all cell types, including neurons, skin cells, fibroblasts, and skeletal muscle. Brain imaging shows a characteristic leukoencephalopathy with high intensity signals in the corticomedullary junction on diffusion-weighted imaging (DWI), as well as white matter abnormalities in subcortical and brainstem regions. Skin biopsy combined with brain imaging is useful for diagnosis (summary by Sone et al., 2016). The phenotype in some cases is suggestive of Parkinson disease (see 168600) and/or Alzheimer disease (see 104300), consistent with an evolving phenotypic spectrum of adult-onset NIID (summary by Tian et al., 2019).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/355075">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_105400" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Breath-holding Spells</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_226944" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Deficiency of beta-ureidopropionase</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82803" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Inborn glycerol kinase deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355075" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neuronal intranuclear inclusion disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347149" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteodysplastic primordial dwarfism, type 1</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37983697">Syncope: Evaluation and Differential Diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bayard M,
|
||
Gerayli F,
|
||
Holt J</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2023 Nov;108(5):454-463.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37983697" target="_blank">37983697</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34008935">Emergency department management of syncope.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morris J</span><br />
|
||
<span class="medgenPMjournal">Emerg Med Pract</span>
|
||
2021 Jun;23(6):1-24.
|
||
Epub 2021 Jun 1
|
||
<span class="bold">PMID: </span><a href="/pubmed/34008935" target="_blank">34008935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33065105">Management for the Drowning Patient.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Szpilman D,
|
||
Morgan PJ</span><br />
|
||
<span class="medgenPMjournal">Chest</span>
|
||
2021 Apr;159(4):1473-1483.
|
||
Epub 2020 Oct 14
|
||
doi: 10.1016/j.chest.2020.10.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33065105" target="_blank">33065105</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22loss%20of%20consciousness%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (209)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/cg109" target="_blank">UK NICE Clinical Guideline CG109, Transient loss of consciousness ('blackouts') in over 16s, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng127" target="_blank">UK NICE Guideline (NG127), Suspected neurological conditions: recognition and referral, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37891001">Drop attacks: a practical guide.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Manford E,
|
||
Garg A,
|
||
Manford M</span><br />
|
||
<span class="medgenPMjournal">Pract Neurol</span>
|
||
2024 Mar 19;24(2):106-113.
|
||
doi: 10.1136/pn-2023-003791.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37891001" target="_blank">37891001</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37030995">Vasovagal syncope: An overview of pathophysiological mechanisms.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Longo S,
|
||
Legramante JM,
|
||
Rizza S,
|
||
Federici M</span><br />
|
||
<span class="medgenPMjournal">Eur J Intern Med</span>
|
||
2023 Jun;112:6-14.
|
||
Epub 2023 Apr 6
|
||
doi: 10.1016/j.ejim.2023.03.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37030995" target="_blank">37030995</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35562226">Pharmacodynamic analysis of intravenous bolus remimazolam for loss of consciousness in patients undergoing general anaesthesia: a randomised, prospective, double-blind study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chae D,
|
||
Kim HC,
|
||
Song Y,
|
||
Choi YS,
|
||
Han DW</span><br />
|
||
<span class="medgenPMjournal">Br J Anaesth</span>
|
||
2022 Jul;129(1):49-57.
|
||
Epub 2022 May 11
|
||
doi: 10.1016/j.bja.2022.02.040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35562226" target="_blank">35562226</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30269732">The Necessity for Observation after Traumatic Loss of Consciousness.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Sellers W,
|
||
Toy F,
|
||
Klock B</span><br />
|
||
<span class="medgenPMjournal">Am Surg</span>
|
||
2018 Sep 1;84(9):e426-e427.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30269732" target="_blank">30269732</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26042877">Syncope due to Autonomic Dysfunction: Diagnosis and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Adkisson WO,
|
||
Benditt DG</span><br />
|
||
<span class="medgenPMjournal">Med Clin North Am</span>
|
||
2015 Jul;99(4):691-710.
|
||
Epub 2015 Apr 15
|
||
doi: 10.1016/j.mcna.2015.02.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26042877" target="_blank">26042877</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Loss%20of%20consciousness%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2514)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34817264">Loss of consciousness, encephalopathy and hereditary haemorrhagic telangiectasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gentry R,
|
||
Tokala A,
|
||
Wood H</span><br />
|
||
<span class="medgenPMjournal">Br J Hosp Med (Lond)</span>
|
||
2021 Nov 2;82(11):1-3.
|
||
Epub 2021 Nov 23
|
||
doi: 10.12968/hmed.2021.0287.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34817264" target="_blank">34817264</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34008935">Emergency department management of syncope.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morris J</span><br />
|
||
<span class="medgenPMjournal">Emerg Med Pract</span>
|
||
2021 Jun;23(6):1-24.
|
||
Epub 2021 Jun 1
|
||
<span class="bold">PMID: </span><a href="/pubmed/34008935" target="_blank">34008935</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30421679">Breath-Holding Spells in Pediatrics: A Narrative Review of the Current Evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leung AKC,
|
||
Leung AAM,
|
||
Wong AHC,
|
||
Hon KL</span><br />
|
||
<span class="medgenPMjournal">Curr Pediatr Rev</span>
|
||
2019;15(1):22-29.
|
||
doi: 10.2174/1573396314666181113094047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30421679" target="_blank">30421679</a><a href="/pmc/articles/PMC6696822" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30269732">The Necessity for Observation after Traumatic Loss of Consciousness.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Sellers W,
|
||
Toy F,
|
||
Klock B</span><br />
|
||
<span class="medgenPMjournal">Am Surg</span>
|
||
2018 Sep 1;84(9):e426-e427.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30269732" target="_blank">30269732</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17892404">The mayo classification system for traumatic brain injury severity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Malec JF,
|
||
Brown AW,
|
||
Leibson CL,
|
||
Flaada JT,
|
||
Mandrekar JN,
|
||
Diehl NN,
|
||
Perkins PK</span><br />
|
||
<span class="medgenPMjournal">J Neurotrauma</span>
|
||
2007 Sep;24(9):1417-24.
|
||
doi: 10.1089/neu.2006.0245.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17892404" target="_blank">17892404</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Loss%20of%20consciousness%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2579)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37491938">Zuranolone for the Treatment of Postpartum Depression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Deligiannidis KM,
|
||
Meltzer-Brody S,
|
||
Maximos B,
|
||
Peeper EQ,
|
||
Freeman M,
|
||
Lasser R,
|
||
Bullock A,
|
||
Kotecha M,
|
||
Li S,
|
||
Forrestal F,
|
||
Rana N,
|
||
Garcia M,
|
||
Leclair B,
|
||
Doherty J</span><br />
|
||
<span class="medgenPMjournal">Am J Psychiatry</span>
|
||
2023 Sep 1;180(9):668-675.
|
||
Epub 2023 Jul 26
|
||
doi: 10.1176/appi.ajp.20220785.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37491938" target="_blank">37491938</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37030995">Vasovagal syncope: An overview of pathophysiological mechanisms.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Longo S,
|
||
Legramante JM,
|
||
Rizza S,
|
||
Federici M</span><br />
|
||
<span class="medgenPMjournal">Eur J Intern Med</span>
|
||
2023 Jun;112:6-14.
|
||
Epub 2023 Apr 6
|
||
doi: 10.1016/j.ejim.2023.03.025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37030995" target="_blank">37030995</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36627210">Understanding the Neural Mechanisms of General Anesthesia from Interaction with Sleep-Wake State: A Decade of Discovery.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bao WW,
|
||
Jiang S,
|
||
Qu WM,
|
||
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<div class="nl"><a target="_blank" href="/pubmed/27737513">Pharmacologic interventions for treating phantom limb pain.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30269732">The Necessity for Observation after Traumatic Loss of Consciousness.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25702218">Acute loss of consciousness.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tristán B,
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Gleichgerrcht E,
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<span class="bold">PMID: </span><a href="/pubmed/25702218" target="_blank">25702218</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Loss%20of%20consciousness%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1507)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38295384">Electroencephalogram Biomarkers from Anesthesia Induction to Identify Vulnerable Patients at Risk for Postoperative Delirium.</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37491938">Zuranolone for the Treatment of Postpartum Depression.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Deligiannidis KM,
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Meltzer-Brody S,
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Maximos B,
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<span class="bold">PMID: </span><a href="/pubmed/37491938" target="_blank">37491938</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30269732">The Necessity for Observation after Traumatic Loss of Consciousness.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
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Sellers W,
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Toy F,
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Klock B</span><br />
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2018 Sep 1;84(9):e426-e427.
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<div class="nl"><a target="_blank" href="/pubmed/25702218">Acute loss of consciousness.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Tristán B,
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Gleichgerrcht E,
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Manes F</span><br />
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<span class="medgenPMjournal">Handb Clin Neurol</span>
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2015;127:195-204.
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doi: 10.1016/B978-0-444-52892-6.00013-1.
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<span class="bold">PMID: </span><a href="/pubmed/25702218" target="_blank">25702218</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/19758692">Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kuppermann N,
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Dayan PS,
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Atabaki SM,
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Borgialli DA,
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Schunk JE,
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Mahajan P,
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Glass TF,
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Gerardi MJ,
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Melville KA,
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Muizelaar JP,
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Wisner DH,
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Zuspan SJ,
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Dean JM,
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Wootton-Gorges SL;
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Pediatric Emergency Care Applied Research Network (PECARN)</span><br />
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2009 Oct 3;374(9696):1160-70.
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<span class="bold">PMID: </span><a href="/pubmed/19758692" target="_blank">19758692</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Loss%20of%20consciousness%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1803)</a></div></div>
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</div>
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||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">
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||
<div class="nl"><a target="_blank" href="/pubmed/38272015">Prevalence and Trajectories of Post-COVID-19 Neurological Manifestations: A Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Giussani G,
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Westenberg E,
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Garcia-Azorin D,
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Bianchi E,
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Yusof Khan AHK,
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Allegri RF,
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Atalar AÇ,
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Baykan B,
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Crivelli L,
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Fornari A,
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Frontera JA,
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Guekht A,
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Helbok R,
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Hoo FK,
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Kivipelto M,
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Leonardi M,
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Lopez Rocha AS,
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Mangialasche F,
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Marcassoli A,
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Özdag Acarli AN,
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Ozge A,
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Prasad K,
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Prasad M,
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Sviatskaia E,
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Thakur K,
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Vogrig A,
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Leone M,
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||
Winkler AS;
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||
Global COVID-19 Neuro Research Coalition</span><br />
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<span class="medgenPMjournal">Neuroepidemiology</span>
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||
2024;58(2):120-133.
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||
Epub 2024 Jan 25
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||
doi: 10.1159/000536352.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38272015" target="_blank">38272015</a></div>
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||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38261005">Remimazolam versus propofol for sedation in gastrointestinal endoscopy and colonoscopy within elderly patients: a meta-analysis of randomized controlled trials.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ahmer W,
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Imtiaz S,
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Alam DM,
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Ahmed K,
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Sajid B,
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Yousuf J,
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Asnani S,
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Fahim MAA,
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Ali R,
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Mansoor M,
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Safdar MT,
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Anjum MU,
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Hasanain M,
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||
Larik MO</span><br />
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<span class="medgenPMjournal">Eur J Clin Pharmacol</span>
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||
2024 Apr;80(4):493-503.
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||
Epub 2024 Jan 23
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||
doi: 10.1007/s00228-024-03624-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38261005" target="_blank">38261005</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37632535">Ocular microtremor: a structured review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Graham L,
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||
Das J,
|
||
Vitorio R,
|
||
McDonald C,
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Walker R,
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Godfrey A,
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Morris R,
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||
Stuart S</span><br />
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<span class="medgenPMjournal">Exp Brain Res</span>
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||
2023 Sep;241(9):2191-2203.
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||
Epub 2023 Aug 26
|
||
doi: 10.1007/s00221-023-06691-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37632535" target="_blank">37632535</a><a href="/pmc/articles/PMC10471653" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28786035">Cardiac Harms of Sofosbuvir: Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Caldeira D,
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Rodrigues FB,
|
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Duarte MM,
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Sterrantino C,
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Barra M,
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Gonçalves N,
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Pinto FJ,
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Ferreira JJ,
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Costa J</span><br />
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<span class="medgenPMjournal">Drug Saf</span>
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2018 Jan;41(1):77-86.
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doi: 10.1007/s40264-017-0586-2.
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||
<span class="bold">PMID: </span><a href="/pubmed/28786035" target="_blank">28786035</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27737513">Pharmacologic interventions for treating phantom limb pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alviar MJ,
|
||
Hale T,
|
||
Dungca M</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2016 Oct 14;10(10):CD006380.
|
||
doi: 10.1002/14651858.CD006380.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27737513" target="_blank">27737513</a><a href="/pmc/articles/PMC6472447" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Loss%20of%20consciousness%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (61)</a></div></div>
|
||
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|
||
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22loss%20of%20consciousness%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Loss%20of%20consciousness%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/cg109">NICE, 2023</a><div>UK NICE Clinical Guideline CG109, Transient loss of consciousness ('blackouts') in over 16s, 2023</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng127">NICE, 2023</a><div>UK NICE Guideline (NG127), Suspected neurological conditions: recognition and referral, 2023</div></li></ul></div>
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