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<meta name="keywords" content="C0024623, apc, ca - cancer of stomach, ca lesser curvature - stomach, cancer of stomach, cancer of the stomach, cancer, gastric, cancer, stomach, cancers, gastric, cancers, stomach, casp10, erbb2, fgfr2, gastric cancer, gastric cancer risk after h. pylori infection, gastric cancer, intestinal, gastric cancer, somatic, gastric cancers, gc, il1b, il1rn, irf1, klf6, kras, malignant gastric neoplasm, malignant gastric tumor, malignant gastric tumour, malignant neoplasm of lesser curve of stomach, malignant neoplasm of stomach, malignant neoplasm of the stomach, malignant stomach neoplasm, malignant tumor of body of stomach, malignant tumor of greater curve of stomach, malignant tumor of lesser curve of stomach, malignant tumor of stomach, malignant tumor of the stomach, malignant tumour of body of stomach, malignant tumour of greater curve of stomach, malignant tumour of lesser curve of stomach, malignant tumour of stomach, malignant tumour of the stomach, mutyh, neoplastic process, pik3ca, stomach cancer, stomach cancers, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer. Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see 120435), familial adenomatous polyposis (FAP; 175100), Peutz-Jeghers syndrome (PJS; 175200), Cowden disease (CD; 158350), the Li-Fraumeni syndrome (151623), and diffuse gastric and lobular breast cancer syndrome (DGLBC; 137215). Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see 600263)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=44264
|
||
ConceptID=C0024623
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Gastric cancer</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44264</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0024623</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Malignant tumor of stomach; Stomach cancer</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Cancer of stomach (363349007); Gastric cancer (363349007); CA - Cancer of stomach (363349007); Malignant tumor of stomach (363349007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Genes (locations):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="APC - ID: 324 - NCBI Gene" href="/gene/324" class="medgenPMinfo">APC</a> (5q22.2); <a target="_blank" title="CASP10 - ID: 843 - NCBI Gene" href="/gene/843" class="medgenPMinfo">CASP10</a> (2q33.1); <a target="_blank" title="ERBB2 - ID: 2064 - NCBI Gene" href="/gene/2064" class="medgenPMinfo">ERBB2</a> (17q12); <a target="_blank" title="FGFR2 - ID: 2263 - NCBI Gene" href="/gene/2263" class="medgenPMinfo">FGFR2</a> (10q26.13); <a target="_blank" title="IL1B - ID: 3553 - NCBI Gene" href="/gene/3553" class="medgenPMinfo">IL1B</a> (2q14.1); <a target="_blank" title="IL1RN - ID: 3557 - NCBI Gene" href="/gene/3557" class="medgenPMinfo">IL1RN</a> (2q14.1); <a target="_blank" title="IRF1 - ID: 3659 - NCBI Gene" href="/gene/3659" class="medgenPMinfo">IRF1</a> (5q31.1); <a target="_blank" title="KLF6 - ID: 1316 - NCBI Gene" href="/gene/1316" class="medgenPMinfo">KLF6</a> (10p15.2); <a target="_blank" title="KRAS - ID: 3845 - NCBI Gene" href="/gene/3845" class="medgenPMinfo">KRAS</a> (12p12.1); <a target="_blank" title="MUTYH - ID: 4595 - NCBI Gene" href="/gene/4595" class="medgenPMinfo">MUTYH</a> (1p34.1); <a target="_blank" title="PIK3CA - ID: 5290 - NCBI Gene" href="/gene/5290" class="medgenPMinfo">PIK3CA</a> (3q26.32)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0012126">HP:0012126</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0001056" target="_blank">MONDO:0001056</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/613659" target="_blank">613659</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer. Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see 120435), familial adenomatous polyposis (FAP; 175100), Peutz-Jeghers syndrome (PJS; 175200), Cowden disease (CD; 158350), the Li-Fraumeni syndrome (151623), and diffuse gastric and lobular breast cancer syndrome (DGLBC; 137215). Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see 600263). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_1646743"><div><strong>Increased level of L-fucose in urine</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1646743</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4703633</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An increase in the level of L-fucose in the urine.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1646743">Feature record</a> | <a href="/medgen?term=%22Increased%20level%20of%20L-fucose%20in%20urine%22%5BClinical%20Features%5D%20OR%201646743%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_44264"><div><strong>Gastric cancer</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44264</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0024623</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer. Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see 120435), familial adenomatous polyposis (FAP; 175100), Peutz-Jeghers syndrome (PJS; 175200), Cowden disease (CD; 158350), the Li-Fraumeni syndrome (151623), and diffuse gastric and lobular breast cancer syndrome (DGLBC; 137215). Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see 600263).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/44264">Feature record</a> | <a href="/medgen?term=%22Gastric%20cancer%22%5BClinical%20Features%5D%20OR%2044264%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of the digestive system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_44264" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Gastric cancer</a></span></li></ul></li><li><span class="TLline">Abnormality of the genitourinary system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_1646743" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Increased level of L-fucose in urine</a></span></li></ul></li></ul></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_118">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0038356[DISCUI]&test_type=Clinical" ref="ncbi_uid=20958">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=20958" ref="ncbi_uid=20958">V</a></span></span><span class="TLline"><a href="/medgen/20958" ref="tree=GTR&ncbi_uid=20958&link_uid=20958" title="View MedGen record for 'Neoplasm of stomach'">Neoplasm of stomach</a></span><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0024623[DISCUI]&test_type=Clinical" ref="ncbi_uid=44264">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=44264" target="_blank" href="/omim/613659">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=44264" ref="ncbi_uid=44264">V</a></span></span><span class="TLline">Gastric cancer</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/147066" ref="tree=GTR&ncbi_uid=147066&link_uid=147066" title="View MedGen record for 'Gastric carcinoma'">Gastric carcinoma</a></span></li></ul></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/14297" ref="tree=MeSH" title="MedGen record for Malignant neoplastic disease">Malignant neoplastic disease</a></span><ul><li><span class="TLline"><a href="/medgen/195783" ref="tree=MeSH" title="MedGen record for Malignant gastrointestinal tract tumors">Malignant gastrointestinal tract tumors</a></span><ul><li><span class="matched_ds">Gastric cancer</span><ul><li><span class="TLline"><a href="/medgen/147066" ref="tree=MeSH" title="MedGen record for Gastric carcinoma">Gastric carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/859255" ref="tree=MeSH" title="MedGen record for Childhood Gastric Carcinoma">Childhood Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/896878" ref="tree=MeSH" title="MedGen record for Epstein-Barr virus-associated gastric carcinoma">Epstein-Barr virus-associated gastric carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/82961" ref="tree=MeSH" title="MedGen record for Gastric adenocarcinoma">Gastric adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/79019" ref="tree=MeSH" title="MedGen record for Diffuse gastric adenocarcinoma">Diffuse gastric adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1658765" ref="tree=MeSH" title="MedGen record for Metastatic Gastric Adenocarcinoma">Metastatic Gastric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718863" ref="tree=MeSH" title="MedGen record for Proximal Gastric Adenocarcinoma">Proximal Gastric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1649479" ref="tree=MeSH" title="MedGen record for Recurrent Gastric Adenocarcinoma">Recurrent Gastric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1712797" ref="tree=MeSH" title="MedGen record for Refractory Gastric Adenocarcinoma">Refractory Gastric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/328294" ref="tree=MeSH" title="MedGen record for Sporadic Gastric Adenocarcinoma">Sporadic Gastric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1662439" ref="tree=MeSH" title="MedGen record for Unresectable Gastric Adenocarcinoma">Unresectable Gastric Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272661" ref="tree=MeSH" title="MedGen record for Gastric adenosquamous carcinoma">Gastric adenosquamous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/87515" ref="tree=MeSH" title="MedGen record for Gastric body carcinoma">Gastric body carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1621882" ref="tree=MeSH" title="MedGen record for Gastric Body Carcinoma In Situ AJCC v6 and v7">Gastric Body Carcinoma In Situ AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/455930" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v6 Stage">Gastric Cancer by AJCC v6 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1617293" ref="tree=MeSH" title="MedGen record for Stage 0 Gastric Cancer AJCC v6 and v7">Stage 0 Gastric Cancer AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/456313" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v7 Stage">Gastric Cancer by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/452379" ref="tree=MeSH" title="MedGen record for Stage I Gastric Cancer AJCC v7">Stage I Gastric Cancer AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/452380" ref="tree=MeSH" title="MedGen record for Stage II Gastric Cancer AJCC v7">Stage II Gastric Cancer AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/452381" ref="tree=MeSH" title="MedGen record for Stage III Gastric Cancer AJCC v7">Stage III Gastric Cancer AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/452382" ref="tree=MeSH" title="MedGen record for Stage IV Gastric Cancer AJCC v7">Stage IV Gastric Cancer AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612691" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v8 Stage">Gastric Cancer by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1619594" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v8 Clinical Stage">Gastric Cancer by AJCC v8 Clinical Stage</a></span></li><li><span class="TLline"><a href="/medgen/1616050" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v8 Pathologic Stage">Gastric Cancer by AJCC v8 Pathologic Stage</a></span></li><li><span class="TLline"><a href="/medgen/1617289" ref="tree=MeSH" title="MedGen record for Gastric Cancer by AJCC v8 Postneoadjuvant Therapy Stage">Gastric Cancer by AJCC v8 Postneoadjuvant Therapy Stage</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234295" ref="tree=MeSH" title="MedGen record for Gastric cardia carcinoma">Gastric cardia carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/232543" ref="tree=MeSH" title="MedGen record for Gastric cardia adenocarcinoma">Gastric cardia adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1624294" ref="tree=MeSH" title="MedGen record for Gastric Cardia Carcinoma In Situ AJCC v6 and v7">Gastric Cardia Carcinoma In Situ AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1668789" ref="tree=MeSH" title="MedGen record for Gastric Cardia Squamous Cell Carcinoma">Gastric Cardia Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87514" ref="tree=MeSH" title="MedGen record for Gastric fundus carcinoma">Gastric fundus carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1621644" ref="tree=MeSH" title="MedGen record for Gastric Fundus Carcinoma In Situ AJCC v6 and v7">Gastric Fundus Carcinoma In Situ AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/474044" ref="tree=MeSH" title="MedGen record for Gastric Mixed Adenoneuroendocrine Carcinoma">Gastric Mixed Adenoneuroendocrine Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/474042" ref="tree=MeSH" title="MedGen record for Gastric Neuroendocrine Carcinoma">Gastric Neuroendocrine Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/474043" ref="tree=MeSH" title="MedGen record for Gastric Large Cell Neuroendocrine Carcinoma">Gastric Large Cell Neuroendocrine Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272664" ref="tree=MeSH" title="MedGen record for Gastric small cell neuroendocrine carcinoma">Gastric small cell neuroendocrine carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1666857" ref="tree=MeSH" title="MedGen record for Metastatic Gastric Neuroendocrine Carcinoma">Metastatic Gastric Neuroendocrine Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234301" ref="tree=MeSH" title="MedGen record for Gastric pylorus carcinoma">Gastric pylorus carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1628096" ref="tree=MeSH" title="MedGen record for Gastric Pylorus Carcinoma In Situ AJCC v6 and v7">Gastric Pylorus Carcinoma In Situ AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234302" ref="tree=MeSH" title="MedGen record for Gastric squamous cell carcinoma">Gastric squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1656961" ref="tree=MeSH" title="MedGen record for Localized Gastric Carcinoma">Localized Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1660239" ref="tree=MeSH" title="MedGen record for Metastatic Gastric Carcinoma">Metastatic Gastric Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1719475" ref="tree=MeSH" title="MedGen record for Advanced Gastric Carcinoma">Advanced Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1698287" ref="tree=MeSH" title="MedGen record for Locally Advanced Gastric Carcinoma">Locally Advanced Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793749" ref="tree=MeSH" title="MedGen record for Recurrent Metastatic Gastric Carcinoma">Recurrent Metastatic Gastric Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75828" ref="tree=MeSH" title="MedGen record for Recurrent Gastric Carcinoma">Recurrent Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1631246" ref="tree=MeSH" title="MedGen record for Refractory Gastric Carcinoma">Refractory Gastric Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/237029" ref="tree=MeSH" title="MedGen record for Undifferentiated carcinoma of stomach">Undifferentiated carcinoma of stomach</a></span></li><li><span class="TLline"><a href="/medgen/1693015" ref="tree=MeSH" title="MedGen record for Unresectable Gastric Carcinoma">Unresectable Gastric Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87603" ref="tree=MeSH" title="MedGen record for Gastric lymphoma">Gastric lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/232234" ref="tree=MeSH" title="MedGen record for Gastric Hodgkin Lymphoma">Gastric Hodgkin Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/232549" ref="tree=MeSH" title="MedGen record for Gastric non-hodgkin lymphoma">Gastric non-hodgkin lymphoma</a></span><ul><li><span class="TLline"><a href="/medgen/235495" ref="tree=MeSH" title="MedGen record for Gastric Burkitt Lymphoma">Gastric Burkitt Lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/277530" ref="tree=MeSH" title="MedGen record for Gastric diffuse large B-cell lymphoma">Gastric diffuse large B-cell lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/232547" ref="tree=MeSH" title="MedGen record for Gastric mucosa-associated lymphoid tissue lymphoma">Gastric mucosa-associated lymphoid tissue lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/233872" ref="tree=MeSH" title="MedGen record for Gastric T-Cell Non-Hodgkin Lymphoma">Gastric T-Cell Non-Hodgkin Lymphoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1789441" ref="tree=MeSH" title="MedGen record for Gastric Melanoma">Gastric Melanoma</a></span></li><li><span class="TLline"><a href="/medgen/1735081" ref="tree=MeSH" title="MedGen record for Gastric Sarcoma">Gastric Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/232236" ref="tree=MeSH" title="MedGen record for Gastric Kaposi Sarcoma">Gastric Kaposi Sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/234470" ref="tree=MeSH" title="MedGen record for AIDS-Related Gastric Kaposi Sarcoma">AIDS-Related Gastric Kaposi Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/196652" ref="tree=MeSH" title="MedGen record for Gastric leiomyosarcoma">Gastric leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/272663" ref="tree=MeSH" title="MedGen record for Gastric liposarcoma">Gastric liposarcoma</a></span></li><li><span class="TLline"><a href="/medgen/474054" ref="tree=MeSH" title="MedGen record for Gastric Malignant Gastrointestinal Stromal Tumor">Gastric Malignant Gastrointestinal Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/474056" ref="tree=MeSH" title="MedGen record for Gastric Synovial Sarcoma">Gastric Synovial Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1731587" ref="tree=MeSH" title="MedGen record for Gastroblastoma">Gastroblastoma</a></span></li><li><span class="TLline"><a href="/medgen/1754723" ref="tree=MeSH" title="MedGen record for Malignant Fundus Neoplasm">Malignant Fundus Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/233663" ref="tree=MeSH" title="MedGen record for Malignant gastric germ cell tumor">Malignant gastric germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/459624" ref="tree=MeSH" title="MedGen record for Gastric choriocarcinoma">Gastric choriocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233664" ref="tree=MeSH" title="MedGen record for Malignant gastric granular cell tumor">Malignant gastric granular cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/473255" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Neoplasm in the Stomach">Metastatic Malignant Neoplasm in the Stomach</a></span></li><li><span class="TLline"><a href="/medgen/277581" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Gastric Neoplasm">Recurrent Malignant Gastric Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/1779219" ref="tree=MeSH" title="MedGen record for Unresectable Malignant Gastric Neoplasm">Unresectable Malignant Gastric Neoplasm</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_44264"><div><strong>Gastric cancer</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44264</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0024623</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several genes may be associated with an increased risk of gastric cancer. Gastric cancer is a manifestation of a number of inherited cancer predisposition syndromes, including hereditary nonpolyposis colon cancer (HNPCC1; see 120435), familial adenomatous polyposis (FAP; 175100), Peutz-Jeghers syndrome (PJS; 175200), Cowden disease (CD; 158350), the Li-Fraumeni syndrome (151623), and diffuse gastric and lobular breast cancer syndrome (DGLBC; 137215). Canedo et al. (2007) provided a review of genetic susceptibility to gastric cancer in patients infected with Helicobacter pylori (see 600263).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/44264">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_310839"><div><strong>Hereditary diffuse gastric adenocarcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>310839</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1708349</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
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<div class="spaceAbove">Diffuse gastric and lobular breast cancer syndrome (DGLBCS) is associated with an increased risk, in males and females, of diffuse gastric cancer (DGC), a poorly differentiated adenocarcinoma (also referred to as signet ring cell carcinoma or isolated cell-type carcinoma) that infiltrates into the stomach wall, causing thickening of the wall (linitis plastica) without forming a distinct mass. In females with CDH1-related DGLBCS, but not in males, there is also an increased risk for lobular breast cancer (LBC), characterized by small, non-cohesive cells dispersed in the stroma or arranged in single-file infiltrating patterns. Cleft lip with or without cleft palate has also been reported in some individuals with CDH1-related DGLBCS.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/310839">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1849727"><div><strong>Li-Fraumeni syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1849727</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882668</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Li-Fraumeni syndrome is a rare disorder that greatly increases the risk of developing several types of cancer, particularly in children and young adults.\n\nA very similar condition called Li-Fraumeni-like syndrome shares many of the features of classic Li-Fraumeni syndrome. Both conditions significantly increase the chances of developing multiple cancers beginning in childhood; however, the pattern of specific cancers seen in affected family members is different.\n\nThe cancers most often associated with Li-Fraumeni syndrome include breast cancer, a form of bone cancer called osteosarcoma, and cancers of soft tissues (such as muscle) called soft tissue sarcomas. Other cancers commonly seen in this syndrome include brain tumors, cancers of blood-forming tissues (leukemias), and a cancer called adrenocortical carcinoma that affects the outer layer of the adrenal glands (small hormone-producing glands on top of each kidney). Several other types of cancer also occur more frequently in people with Li-Fraumeni syndrome.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1849727">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_44264" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Gastric cancer</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_310839" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary diffuse gastric adenocarcinoma</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1849727" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Li-Fraumeni syndrome 2</a></div></div>
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/34454714">AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Shah SC,
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Piazuelo MB,
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Kuipers EJ,
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Li D</span><br />
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<span class="medgenPMjournal">Gastroenterology</span>
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2021 Oct;161(4):1325-1332.e7.
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Epub 2021 Aug 26
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doi: 10.1053/j.gastro.2021.06.078.
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<span class="bold">PMID: </span><a href="/pubmed/34454714" target="_blank">34454714</a><a href="/pmc/articles/PMC8740554" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28631728">ACG and CAG Clinical Guideline: Management of Dyspepsia.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Moayyedi P,
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Lacy BE,
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Andrews CN,
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Enns RA,
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Howden CW,
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Vakil N</span><br />
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<span class="medgenPMjournal">Am J Gastroenterol</span>
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2017 Jul;112(7):988-1013.
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Epub 2017 Jun 20
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||
doi: 10.1038/ajg.2017.154.
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<span class="bold">PMID: </span><a href="/pubmed/28631728" target="_blank">28631728</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/28071659">ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chey WD,
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Leontiadis GI,
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Howden CW,
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Moss SF</span><br />
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<span class="medgenPMjournal">Am J Gastroenterol</span>
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2017 Feb;112(2):212-239.
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Epub 2017 Jan 10
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doi: 10.1038/ajg.2016.563.
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<span class="bold">PMID: </span><a href="/pubmed/28071659" target="_blank">28071659</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22gastric%20cancer%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (2633)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/gastric.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Gastric Cancer, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng83" target="_blank">UK NICE Guideline (NG83), Oesophago-gastric cancer: assessment and management in adults, 2023</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36959359">Global burden of gastric cancer: epidemiological trends, risk factors, screening and prevention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thrift AP,
|
||
Wenker TN,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Clin Oncol</span>
|
||
2023 May;20(5):338-349.
|
||
Epub 2023 Mar 23
|
||
doi: 10.1038/s41571-023-00747-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36959359" target="_blank">36959359</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36240980">Characteristics of gastric cancer around the world.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">López MJ,
|
||
Carbajal J,
|
||
Alfaro AL,
|
||
Saravia LG,
|
||
Zanabria D,
|
||
Araujo JM,
|
||
Quispe L,
|
||
Zevallos A,
|
||
Buleje JL,
|
||
Cho CE,
|
||
Sarmiento M,
|
||
Pinto JA,
|
||
Fajardo W</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
|
||
2023 Jan;181:103841.
|
||
Epub 2022 Oct 11
|
||
doi: 10.1016/j.critrevonc.2022.103841.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36240980" target="_blank">36240980</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32861308">Gastric cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Smyth EC,
|
||
Nilsson M,
|
||
Grabsch HI,
|
||
van Grieken NC,
|
||
Lordick F</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Aug 29;396(10251):635-648.
|
||
doi: 10.1016/S0140-6736(20)31288-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32861308" target="_blank">32861308</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31362118">Burden of Gastric Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thrift AP,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Clin Gastroenterol Hepatol</span>
|
||
2020 Mar;18(3):534-542.
|
||
Epub 2019 Jul 27
|
||
doi: 10.1016/j.cgh.2019.07.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31362118" target="_blank">31362118</a><a href="/pmc/articles/PMC8859863" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24618998">Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karimi P,
|
||
Islami F,
|
||
Anandasabapathy S,
|
||
Freedman ND,
|
||
Kamangar F</span><br />
|
||
<span class="medgenPMjournal">Cancer Epidemiol Biomarkers Prev</span>
|
||
2014 May;23(5):700-13.
|
||
Epub 2014 Mar 11
|
||
doi: 10.1158/1055-9965.EPI-13-1057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24618998" target="_blank">24618998</a><a href="/pmc/articles/PMC4019373" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (27575)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36240980">Characteristics of gastric cancer around the world.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">López MJ,
|
||
Carbajal J,
|
||
Alfaro AL,
|
||
Saravia LG,
|
||
Zanabria D,
|
||
Araujo JM,
|
||
Quispe L,
|
||
Zevallos A,
|
||
Buleje JL,
|
||
Cho CE,
|
||
Sarmiento M,
|
||
Pinto JA,
|
||
Fajardo W</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
|
||
2023 Jan;181:103841.
|
||
Epub 2022 Oct 11
|
||
doi: 10.1016/j.critrevonc.2022.103841.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36240980" target="_blank">36240980</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35481909">Advances in screening and detection of gastric cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xia JY,
|
||
Aadam AA</span><br />
|
||
<span class="medgenPMjournal">J Surg Oncol</span>
|
||
2022 Jun;125(7):1104-1109.
|
||
doi: 10.1002/jso.26844.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35481909" target="_blank">35481909</a><a href="/pmc/articles/PMC9322671" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32861308">Gastric cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Smyth EC,
|
||
Nilsson M,
|
||
Grabsch HI,
|
||
van Grieken NC,
|
||
Lordick F</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Aug 29;396(10251):635-648.
|
||
doi: 10.1016/S0140-6736(20)31288-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32861308" target="_blank">32861308</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31362118">Burden of Gastric Cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thrift AP,
|
||
El-Serag HB</span><br />
|
||
<span class="medgenPMjournal">Clin Gastroenterol Hepatol</span>
|
||
2020 Mar;18(3):534-542.
|
||
Epub 2019 Jul 27
|
||
doi: 10.1016/j.cgh.2019.07.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31362118" target="_blank">31362118</a><a href="/pmc/articles/PMC8859863" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24618998">Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karimi P,
|
||
Islami F,
|
||
Anandasabapathy S,
|
||
Freedman ND,
|
||
Kamangar F</span><br />
|
||
<span class="medgenPMjournal">Cancer Epidemiol Biomarkers Prev</span>
|
||
2014 May;23(5):700-13.
|
||
Epub 2014 Mar 11
|
||
doi: 10.1158/1055-9965.EPI-13-1057.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24618998" target="_blank">24618998</a><a href="/pmc/articles/PMC4019373" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17886)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36620346">Microbiota in the stomach and application of probiotics to gastroduodenal diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Koga Y</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2022 Dec 21;28(47):6702-6715.
|
||
doi: 10.3748/wjg.v28.i47.6702.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36620346" target="_blank">36620346</a><a href="/pmc/articles/PMC9813937" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35535555">MATTERHORN: phase III study of durvalumab plus FLOT chemotherapy in resectable gastric/gastroesophageal junction cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Janjigian YY,
|
||
Van Cutsem E,
|
||
Muro K,
|
||
Wainberg Z,
|
||
Al-Batran SE,
|
||
Hyung WJ,
|
||
Molena D,
|
||
Marcovitz M,
|
||
Ruscica D,
|
||
Robbins SH,
|
||
Negro A,
|
||
Tabernero J</span><br />
|
||
<span class="medgenPMjournal">Future Oncol</span>
|
||
2022 Jun;18(20):2465-2473.
|
||
Epub 2022 May 10
|
||
doi: 10.2217/fon-2022-0093.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35535555" target="_blank">35535555</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33167735">First-line pembrolizumab/placebo plus trastuzumab and chemotherapy in HER2-positive advanced gastric cancer: KEYNOTE-811.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chung HC,
|
||
Bang YJ,
|
||
S Fuchs C,
|
||
Qin SK,
|
||
Satoh T,
|
||
Shitara K,
|
||
Tabernero J,
|
||
Van Cutsem E,
|
||
Alsina M,
|
||
Cao ZA,
|
||
Lu J,
|
||
Bhagia P,
|
||
Shih CS,
|
||
Janjigian YY</span><br />
|
||
<span class="medgenPMjournal">Future Oncol</span>
|
||
2021 Feb;17(5):491-501.
|
||
Epub 2020 Nov 10
|
||
doi: 10.2217/fon-2020-0737.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33167735" target="_blank">33167735</a><a href="/pmc/articles/PMC8411394" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32894370">Gastric cancer: a comprehensive review of current and future treatment strategies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sexton RE,
|
||
Al Hallak MN,
|
||
Diab M,
|
||
Azmi AS</span><br />
|
||
<span class="medgenPMjournal">Cancer Metastasis Rev</span>
|
||
2020 Dec;39(4):1179-1203.
|
||
Epub 2020 Sep 7
|
||
doi: 10.1007/s10555-020-09925-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32894370" target="_blank">32894370</a><a href="/pmc/articles/PMC7680370" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26896760">Magnifying endoscopy simple diagnostic algorithm for early gastric cancer (MESDA-G).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muto M,
|
||
Yao K,
|
||
Kaise M,
|
||
Kato M,
|
||
Uedo N,
|
||
Yagi K,
|
||
Tajiri H</span><br />
|
||
<span class="medgenPMjournal">Dig Endosc</span>
|
||
2016 May;28(4):379-393.
|
||
Epub 2016 Apr 22
|
||
doi: 10.1111/den.12638.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26896760" target="_blank">26896760</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15875)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35598628">Long-Term Impact of Helicobacter pylori Eradication Therapy on Gastric Cancer Incidence and Mortality in Healthy Infected Individuals: A Meta-Analysis Beyond 10 Years of Follow-Up.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Yuan Y,
|
||
Moayyedi P</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2022 Sep;163(3):754-756.e1.
|
||
Epub 2022 May 19
|
||
doi: 10.1053/j.gastro.2022.05.027.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35598628" target="_blank">35598628</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34309666">Global Incidence and Mortality of Gastric Cancer, 1980-2018.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wong MCS,
|
||
Huang J,
|
||
Chan PSF,
|
||
Choi P,
|
||
Lao XQ,
|
||
Chan SM,
|
||
Teoh A,
|
||
Liang P</span><br />
|
||
<span class="medgenPMjournal">JAMA Netw Open</span>
|
||
2021 Jul 1;4(7):e2118457.
|
||
doi: 10.1001/jamanetworkopen.2021.18457.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34309666" target="_blank">34309666</a><a href="/pmc/articles/PMC8314143" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29108643">Gastric cancer diagnosis after presentation to the ED: The independent association of presenting location and outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Solsky I,
|
||
Rapkin B,
|
||
Wong K,
|
||
Friedmann P,
|
||
Muscarella P,
|
||
In H</span><br />
|
||
<span class="medgenPMjournal">Am J Surg</span>
|
||
2018 Aug;216(2):286-292.
|
||
Epub 2017 Nov 3
|
||
doi: 10.1016/j.amjsurg.2017.10.030.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29108643" target="_blank">29108643</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20123339">Meta-analysis of effectiveness and safety of D2 plus para-aortic lymphadenectomy for resectable gastric cancer.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen XZ,
|
||
Hu JK,
|
||
Zhou ZG,
|
||
Rui YY,
|
||
Yang K,
|
||
Wang L,
|
||
Zhang B,
|
||
Chen ZX,
|
||
Chen JP</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Surg</span>
|
||
2010 Jan;210(1):100-5.
|
||
Epub 2009 Nov 4
|
||
doi: 10.1016/j.jamcollsurg.2009.09.033.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20123339" target="_blank">20123339</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11706759">Gastric cancer in Brazil.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lourenço LG,
|
||
Hamada GS</span><br />
|
||
<span class="medgenPMjournal">Gastric Cancer</span>
|
||
2001;4(2):103-5.
|
||
doi: 10.1007/pl00011722.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11706759" target="_blank">11706759</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (24706)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35461691">Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer with multitask deep learning: a retrospective study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jiang Y,
|
||
Zhang Z,
|
||
Yuan Q,
|
||
Wang W,
|
||
Wang H,
|
||
Li T,
|
||
Huang W,
|
||
Xie J,
|
||
Chen C,
|
||
Sun Z,
|
||
Yu J,
|
||
Xu Y,
|
||
Poultsides GA,
|
||
Xing L,
|
||
Zhou Z,
|
||
Li G,
|
||
Li R</span><br />
|
||
<span class="medgenPMjournal">Lancet Digit Health</span>
|
||
2022 May;4(5):e340-e350.
|
||
doi: 10.1016/S2589-7500(22)00040-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35461691" target="_blank">35461691</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34454714">AGA Clinical Practice Update on the Diagnosis and Management of Atrophic Gastritis: Expert Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah SC,
|
||
Piazuelo MB,
|
||
Kuipers EJ,
|
||
Li D</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2021 Oct;161(4):1325-1332.e7.
|
||
Epub 2021 Aug 26
|
||
doi: 10.1053/j.gastro.2021.06.078.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34454714" target="_blank">34454714</a><a href="/pmc/articles/PMC8740554" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32499390">Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hatta W,
|
||
Tsuji Y,
|
||
Yoshio T,
|
||
Kakushima N,
|
||
Hoteya S,
|
||
Doyama H,
|
||
Nagami Y,
|
||
Hikichi T,
|
||
Kobayashi M,
|
||
Morita Y,
|
||
Sumiyoshi T,
|
||
Iguchi M,
|
||
Tomida H,
|
||
Inoue T,
|
||
Koike T,
|
||
Mikami T,
|
||
Hasatani K,
|
||
Nishikawa J,
|
||
Matsumura T,
|
||
Nebiki H,
|
||
Nakamatsu D,
|
||
Ohnita K,
|
||
Suzuki H,
|
||
Ueyama H,
|
||
Hayashi Y,
|
||
Sugimoto M,
|
||
Yamaguchi S,
|
||
Michida T,
|
||
Yada T,
|
||
Asahina Y,
|
||
Narasaka T,
|
||
Kuribasyashi S,
|
||
Kiyotoki S,
|
||
Mabe K,
|
||
Nakamura T,
|
||
Nakaya N,
|
||
Fujishiro M,
|
||
Masamune A</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
2021 Mar;70(3):476-484.
|
||
Epub 2020 Jun 4
|
||
doi: 10.1136/gutjnl-2019-319926.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32499390" target="_blank">32499390</a><a href="/pmc/articles/PMC7873424" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32001553">Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arnold M,
|
||
Park JY,
|
||
Camargo MC,
|
||
Lunet N,
|
||
Forman D,
|
||
Soerjomataram I</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
2020 May;69(5):823-829.
|
||
Epub 2020 Jan 30
|
||
doi: 10.1136/gutjnl-2019-320234.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32001553" target="_blank">32001553</a><a href="/pmc/articles/PMC8520492" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25320521">Gastric cancer: prevention, screening and early diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pasechnikov V,
|
||
Chukov S,
|
||
Fedorov E,
|
||
Kikuste I,
|
||
Leja M</span><br />
|
||
<span class="medgenPMjournal">World J Gastroenterol</span>
|
||
2014 Oct 14;20(38):13842-62.
|
||
doi: 10.3748/wjg.v20.i38.13842.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25320521" target="_blank">25320521</a><a href="/pmc/articles/PMC4194567" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20003)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38176660">Global Prevalence of Helicobacter pylori Infection and Incidence of Gastric Cancer Between 1980 and 2022.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen YC,
|
||
Malfertheiner P,
|
||
Yu HT,
|
||
Kuo CL,
|
||
Chang YY,
|
||
Meng FT,
|
||
Wu YX,
|
||
Hsiao JL,
|
||
Chen MJ,
|
||
Lin KP,
|
||
Wu CY,
|
||
Lin JT,
|
||
O'Morain C,
|
||
Megraud F,
|
||
Lee WC,
|
||
El-Omar EM,
|
||
Wu MS,
|
||
Liou JM</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2024 Apr;166(4):605-619.
|
||
Epub 2024 Jan 2
|
||
doi: 10.1053/j.gastro.2023.12.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38176660" target="_blank">38176660</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35565732">Diet and Risk of Gastric Cancer: An Umbrella Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bouras E,
|
||
Tsilidis KK,
|
||
Triggi M,
|
||
Siargkas A,
|
||
Chourdakis M,
|
||
Haidich AB</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2022 Apr 23;14(9)
|
||
doi: 10.3390/nu14091764.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35565732" target="_blank">35565732</a><a href="/pmc/articles/PMC9105055" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32205420">Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford AC,
|
||
Yuan Y,
|
||
Moayyedi P</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
2020 Dec;69(12):2113-2121.
|
||
Epub 2020 Mar 23
|
||
doi: 10.1136/gutjnl-2020-320839.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32205420" target="_blank">32205420</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29579788">Risk Factors for Gastric Cancer: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yusefi AR,
|
||
Bagheri Lankarani K,
|
||
Bastani P,
|
||
Radinmanesh M,
|
||
Kavosi Z</span><br />
|
||
<span class="medgenPMjournal">Asian Pac J Cancer Prev</span>
|
||
2018 Mar 27;19(3):591-603.
|
||
doi: 10.22034/APJCP.2018.19.3.591.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29579788" target="_blank">29579788</a><a href="/pmc/articles/PMC5980829" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26836587">Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee YC,
|
||
Chiang TH,
|
||
Chou CK,
|
||
Tu YK,
|
||
Liao WC,
|
||
Wu MS,
|
||
Graham DY</span><br />
|
||
<span class="medgenPMjournal">Gastroenterology</span>
|
||
2016 May;150(5):1113-1124.e5.
|
||
Epub 2016 Feb 2
|
||
doi: 10.1053/j.gastro.2016.01.028.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26836587" target="_blank">26836587</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gastric%20cancer%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1212)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet mgSection" id="ID_106">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (28)</a></li>
|
||
<li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A3%5F23" target="_blank">FISH-interphase (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (36)</a></li>
|
||
<li><a href="/gtr/tests?term=C0024623%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (6)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0024623%5bDISCUI%5d" target="_blank">See all (48)</a></total></li>
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||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=613659" target="_blank">OMIM</a></li><li><a href="https://clinicaltrials.gov/search?cond=Gastric%20cancer" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
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|
||
<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22gastric%20cancer%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Gastric%20cancer%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/gastric.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Gastric Cancer, 2023</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng83">NICE, 2023</a><div>UK NICE Guideline (NG83), Oesophago-gastric cancer: assessment and management in adults, 2023</div></li></ul></div>
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|
||
<div class="portlet mgSection" id="ID_115">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=147575%20147679%20147720%20164870%20171834%20176943%20190070%20601762%20602053%20604933%20611731" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=324[geneid]" target="_blank">View APC variations in ClinVar</a></li><li><a href="/clinvar/?term=843[geneid]" target="_blank">View CASP10 variations in ClinVar</a></li><li><a href="/clinvar/?term=1316[geneid]" target="_blank">View KLF6 variations in ClinVar</a></li><li><a href="/clinvar/?term=2064[geneid]" target="_blank">View ERBB2 variations in ClinVar</a></li><li><a href="/clinvar/?term=2263[geneid]" target="_blank">View FGFR2 variations in ClinVar</a></li><li><a href="/clinvar/?term=3553[geneid]" target="_blank">View IL1B variations in ClinVar</a></li><li><a href="/clinvar/?term=3557[geneid]" target="_blank">View IL1RN variations in ClinVar</a></li><li><a href="/clinvar/?term=3659[geneid]" target="_blank">View IRF1 variations in ClinVar</a></li><li><a href="/clinvar/?term=3845[geneid]" target="_blank">View KRAS variations in ClinVar</a></li><li><a href="/clinvar/?term=4595[geneid]" target="_blank">View MUTYH variations in ClinVar</a></li><li><a href="/clinvar/?term=5290[geneid]" target="_blank">View PIK3CA variations in ClinVar</a></li><li><a href="/nuccore/166064018,171906587,176866166,194018735,210032106,224809245,237858742,239582780,254553324,296179406,299116992" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=613659" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
|
||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/gastric_cancer" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Gastric%20cancer" target="_blank">MedlinePlus</a></li></ul></div>
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