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<meta name="keywords" content="C0007131, carcinoma, non small cell lung, carcinoma, non-small cell lung, carcinoma, non-small-cell lung, carcinomas, non-small-cell lung, lung carcinoma, non-small-cell, lung carcinomas, non-small-cell, lung non-small cell carcinoma, neoplastic process, non rare in europe: non-small cell lung cancer, non small cell lung cancer nos, non small cell lung carcinoma, non-small cell cancer of lung, non-small cell cancer of the lung, non-small cell carcinoma of lung, non-small cell carcinoma of the lung, non-small cell lung cancer, non-small cell lung carcinoma, non-small cell lung carcinoma (disease), non-small-cell lung carcinoma, non-small-cell lung carcinomas, nonsmall cell lung cancer, nsclc, nsclc - non-small cell lung cancer, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=40104
ConceptID=C0007131
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Non-small cell lung carcinoma<span class="h1sub">(NSCLC)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>40104</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0007131</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Non-small cell lung cancer; NSCLC</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Non-small cell lung cancer (254637007); NSCLC - Non-small cell lung cancer (254637007)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0030358">HP:0030358</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0005233" target="_blank">MONDO:0005233</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/211980" target="_blank">211980</a></td></tr>
<tr><td>Orphanet:</td>
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&amp;Expert=488201">ORPHA488201</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A group of at least three distinct histological types of lung cancer, including non-small cell squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. Non-small cell lung carcinomas have a poor response to conventional chemotherapy. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0007131[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=40104">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=40104" target="_blank" href="/omim/211980">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=40104" ref="ncbi_uid=40104">V</a></span></span><span class="TLline">Non-small cell lung carcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19750" ref="tree=MeSH" title="MedGen record for Disease, Respiratory Tract">Disease, Respiratory Tract</a></span><ul><li><span class="TLline"><a href="/medgen/14233" ref="tree=MeSH" title="MedGen record for Abnormality of the bronchi">Abnormality of the bronchi</a></span><ul><li><span class="TLline"><a href="/medgen/2735" ref="tree=MeSH" title="MedGen record for Bronchial neoplasm">Bronchial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2872" ref="tree=MeSH" title="MedGen record for Bronchogenic carcinoma">Bronchogenic carcinoma</a></span><ul><li><span class="matched_ds">Non-small cell lung carcinoma</span><ul><li><span class="TLline"><a href="/medgen/79006" ref="tree=MeSH" title="MedGen record for Adenosquamous lung carcinoma">Adenosquamous lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1628189" ref="tree=MeSH" title="MedGen record for Lung Adenosquamous Carcinoma by AJCC v7 Stage">Lung Adenosquamous Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1614221" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Adenosquamous Carcinoma AJCC v6 and v7">Stage 0 Lung Adenosquamous Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/167743" ref="tree=MeSH" title="MedGen record for Stage I Lung Adenosquamous Carcinoma AJCC v7">Stage I Lung Adenosquamous Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167744" ref="tree=MeSH" title="MedGen record for Stage II Lung Adenosquamous Carcinoma AJCC v7">Stage II Lung Adenosquamous Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167745" ref="tree=MeSH" title="MedGen record for Stage III Lung Adenosquamous Carcinoma AJCC v7">Stage III Lung Adenosquamous Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/163171" ref="tree=MeSH" title="MedGen record for Stage IV Lung Adenosquamous Carcinoma AJCC v7">Stage IV Lung Adenosquamous Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1663583" ref="tree=MeSH" title="MedGen record for Metastatic Lung Adenosquamous Carcinoma">Metastatic Lung Adenosquamous Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793835" ref="tree=MeSH" title="MedGen record for Advanced Lung Adenosquamous Carcinoma">Advanced Lung Adenosquamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1771112" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Adenosquamous Carcinoma">Locally Advanced Lung Adenosquamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233260" ref="tree=MeSH" title="MedGen record for Occult Lung Adenosquamous Carcinoma">Occult Lung Adenosquamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163170" ref="tree=MeSH" title="MedGen record for Recurrent Lung Adenosquamous Carcinoma">Recurrent Lung Adenosquamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/859244" ref="tree=MeSH" title="MedGen record for Childhood Lung Non-Small Cell Carcinoma">Childhood Lung Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/91060" ref="tree=MeSH" title="MedGen record for Large cell lung carcinoma">Large cell lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/231419" ref="tree=MeSH" title="MedGen record for Basaloid large cell lung carcinoma">Basaloid large cell lung carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/226828" ref="tree=MeSH" title="MedGen record for Large cell carcinoma with rhabdoid phenotype">Large cell carcinoma with rhabdoid phenotype</a></span></li><li><span class="TLline"><a href="/medgen/317518" ref="tree=MeSH" title="MedGen record for Large cell lung carcinoma, clear cell variant">Large cell lung carcinoma, clear cell variant</a></span></li><li><span class="TLline"><a href="/medgen/1617516" ref="tree=MeSH" title="MedGen record for Lung Large Cell Carcinoma by AJCC v7 Stage">Lung Large Cell Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1626534" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Large Cell Carcinoma AJCC v6 and v7">Stage 0 Lung Large Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163488" ref="tree=MeSH" title="MedGen record for Stage I Lung Large Cell Carcinoma AJCC v7">Stage I Lung Large Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167747" ref="tree=MeSH" title="MedGen record for Stage II Lung Large Cell Carcinoma AJCC v7">Stage II Lung Large Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/208935" ref="tree=MeSH" title="MedGen record for Stage III Lung Large Cell Carcinoma AJCC v7">Stage III Lung Large Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/163173" ref="tree=MeSH" title="MedGen record for Stage IV Lung Large Cell Carcinoma AJCC v7">Stage IV Lung Large Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235399" ref="tree=MeSH" title="MedGen record for Lung occult large cell carcinoma">Lung occult large cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163172" ref="tree=MeSH" title="MedGen record for Recurrent Lung Large Cell Carcinoma">Recurrent Lung Large Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/57744" ref="tree=MeSH" title="MedGen record for Lung adenocarcinoma">Lung adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233130" ref="tree=MeSH" title="MedGen record for Acinar lung adenocarcinoma">Acinar lung adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1626367" ref="tree=MeSH" title="MedGen record for Invasive Lung Mucinous Adenocarcinoma">Invasive Lung Mucinous Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/883345" ref="tree=MeSH" title="MedGen record for Lepidic Adenocarcinoma">Lepidic Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1622442" ref="tree=MeSH" title="MedGen record for Lung Adenocarcinoma by AJCC v7 Stage">Lung Adenocarcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1618775" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Adenocarcinoma AJCC v6 and v7">Stage 0 Lung Adenocarcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163489" ref="tree=MeSH" title="MedGen record for Stage I Lung Adenocarcinoma AJCC v7">Stage I Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/163490" ref="tree=MeSH" title="MedGen record for Stage II Lung Adenocarcinoma AJCC v7">Stage II Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/208936" ref="tree=MeSH" title="MedGen record for Stage III Lung Adenocarcinoma AJCC v7">Stage III Lung Adenocarcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/163491" ref="tree=MeSH" title="MedGen record for Stage IV Lung Adenocarcinoma AJCC v7">Stage IV Lung Adenocarcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1620128" ref="tree=MeSH" title="MedGen record for Lung adenocarcinoma in situ">Lung adenocarcinoma in situ</a></span><ul><li><span class="TLline"><a href="/medgen/1618107" ref="tree=MeSH" title="MedGen record for Lung Mucinous Adenocarcinoma In Situ">Lung Mucinous Adenocarcinoma In Situ</a></span></li><li><span class="TLline"><a href="/medgen/1621951" ref="tree=MeSH" title="MedGen record for Lung Non-Mucinous Adenocarcinoma In Situ">Lung Non-Mucinous Adenocarcinoma In Situ</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/313370" ref="tree=MeSH" title="MedGen record for Lung colloid adenocarcinoma">Lung colloid adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1621526" ref="tree=MeSH" title="MedGen record for Lung Enteric Adenocarcinoma">Lung Enteric Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/353690" ref="tree=MeSH" title="MedGen record for Lung Fetal Adenocarcinoma">Lung Fetal Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/277443" ref="tree=MeSH" title="MedGen record for Lung occult adenocarcinoma">Lung occult adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1660921" ref="tree=MeSH" title="MedGen record for Metastatic Lung Adenocarcinoma">Metastatic Lung Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1786216" ref="tree=MeSH" title="MedGen record for Advanced Lung Adenocarcinoma">Advanced Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1763375" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Adenocarcinoma">Locally Advanced Lung Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/2871" ref="tree=MeSH" title="MedGen record for Minimally invasive lung adenocarcinoma">Minimally invasive lung adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/266090" ref="tree=MeSH" title="MedGen record for Minimally Invasive Lung Mucinous Adenocarcinoma">Minimally Invasive Lung Mucinous Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/266089" ref="tree=MeSH" title="MedGen record for Nonmucinous bronchioloalveolar adenocarcinoma">Nonmucinous bronchioloalveolar adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277495" ref="tree=MeSH" title="MedGen record for Papillary lung adenocarcinoma">Papillary lung adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/926281" ref="tree=MeSH" title="MedGen record for Lung Micropapillary Adenocarcinoma">Lung Micropapillary Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/167748" ref="tree=MeSH" title="MedGen record for Recurrent Lung Adenocarcinoma">Recurrent Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1791973" ref="tree=MeSH" title="MedGen record for Refractory Lung Adenocarcinoma">Refractory Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234799" ref="tree=MeSH" title="MedGen record for Solid Lung Adenocarcinoma">Solid Lung Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1772480" ref="tree=MeSH" title="MedGen record for Unresectable Lung Adenocarcinoma">Unresectable Lung Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612118" ref="tree=MeSH" title="MedGen record for Lung Non-Small Cell Cancer by AJCC v7 Stage">Lung Non-Small Cell Cancer by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1620691" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Non-Small Cell Cancer AJCC v6 and v7">Stage 0 Lung Non-Small Cell Cancer AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/124466" ref="tree=MeSH" title="MedGen record for Stage I Lung Non-Small Cell Cancer AJCC v7">Stage I Lung Non-Small Cell Cancer AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/234820" ref="tree=MeSH" title="MedGen record for Stage IA Lung Non-Small Cell Carcinoma AJCC v7">Stage IA Lung Non-Small Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/277679" ref="tree=MeSH" title="MedGen record for Stage IB Lung Non-Small Cell Carcinoma AJCC v7">Stage IB Lung Non-Small Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/82935" ref="tree=MeSH" title="MedGen record for Stage II Lung Non-Small Cell Cancer AJCC v7">Stage II Lung Non-Small Cell Cancer AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/277687" ref="tree=MeSH" title="MedGen record for Stage IIA Lung Non-Small Cell Carcinoma AJCC v7">Stage IIA Lung Non-Small Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/233490" ref="tree=MeSH" title="MedGen record for Stage IIB Lung Non-Small Cell Carcinoma AJCC v7">Stage IIB Lung Non-Small Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/82936" ref="tree=MeSH" title="MedGen record for Stage III Lung Non-Small Cell Cancer AJCC v7">Stage III Lung Non-Small Cell Cancer AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/75903" ref="tree=MeSH" title="MedGen record for Stage IIIA Lung Non-Small Cell Cancer AJCC v7">Stage IIIA Lung Non-Small Cell Cancer AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/124544" ref="tree=MeSH" title="MedGen record for Stage IIIB Lung Non-Small Cell Cancer AJCC v7">Stage IIIB Lung Non-Small Cell Cancer AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83018" ref="tree=MeSH" title="MedGen record for Stage IV Non-Small Cell Lung Cancer">Stage IV Non-Small Cell Lung Cancer</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1660179" ref="tree=MeSH" title="MedGen record for Lung Non-Squamous Non-Small Cell Carcinoma">Lung Non-Squamous Non-Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/926287" ref="tree=MeSH" title="MedGen record for Metastatic Lung Non-Squamous Non-Small Cell Carcinoma">Metastatic Lung Non-Squamous Non-Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1644529" ref="tree=MeSH" title="MedGen record for Advanced Lung Non-Squamous Non-Small Cell Carcinoma">Advanced Lung Non-Squamous Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1667050" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Non-Squamous Non-Small Cell Carcinoma">Locally Advanced Lung Non-Squamous Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1791075" ref="tree=MeSH" title="MedGen record for Metastatic Lung Large Cell Neuroendocrine Carcinoma">Metastatic Lung Large Cell Neuroendocrine Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/925836" ref="tree=MeSH" title="MedGen record for Recurrent Lung Non-Squamous Non-Small Cell Carcinoma">Recurrent Lung Non-Squamous Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1779624" ref="tree=MeSH" title="MedGen record for Refractory Lung Non-Squamous Non-Small Cell Carcinoma">Refractory Lung Non-Squamous Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1690099" ref="tree=MeSH" title="MedGen record for Unresectable Lung Non-Squamous Non-Small Cell Carcinoma">Unresectable Lung Non-Squamous Non-Small Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/353871" ref="tree=MeSH" title="MedGen record for Lung sarcomatoid carcinoma">Lung sarcomatoid carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/354456" ref="tree=MeSH" title="MedGen record for Lung Carcinosarcoma">Lung Carcinosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/83392" ref="tree=MeSH" title="MedGen record for Lung giant cell carcinoma">Lung giant cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/314017" ref="tree=MeSH" title="MedGen record for Lung pleomorphic carcinoma">Lung pleomorphic carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/310951" ref="tree=MeSH" title="MedGen record for Lung Spindle Cell Carcinoma">Lung Spindle Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/61645" ref="tree=MeSH" title="MedGen record for Pulmonary blastoma">Pulmonary blastoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/313374" ref="tree=MeSH" title="MedGen record for Lymphoepithelioma-like lung carcinoma">Lymphoepithelioma-like lung carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1648938" ref="tree=MeSH" title="MedGen record for Metastatic Lung Non-Small Cell Carcinoma">Metastatic Lung Non-Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1701032" ref="tree=MeSH" title="MedGen record for Advanced Lung Non-Small Cell Carcinoma">Advanced Lung Non-Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1670722" ref="tree=MeSH" title="MedGen record for Advanced Lung Non-Small Cell Squamous Carcinoma">Advanced Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1691150" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Non-Small Cell Carcinoma">Locally Advanced Lung Non-Small Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1684528" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Non-Small Cell Squamous Carcinoma">Locally Advanced Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1679728" ref="tree=MeSH" title="MedGen record for Metastatic Lung Non-Small Cell Squamous Carcinoma">Metastatic Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1383559" ref="tree=MeSH" title="MedGen record for Non-small cell squamous lung carcinoma">Non-small cell squamous lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/318199" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Clear Cell Variant">Lung Squamous Cell Carcinoma, Clear Cell Variant</a></span></li><li><span class="TLline"><a href="/medgen/318200" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Papillary Variant">Lung Squamous Cell Carcinoma, Papillary Variant</a></span></li><li><span class="TLline"><a href="/medgen/1750219" ref="tree=MeSH" title="MedGen record for Recurrent Lung Non-Small Cell Squamous Carcinoma">Recurrent Lung Non-Small Cell Squamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1764028" ref="tree=MeSH" title="MedGen record for Refractory Lung Non-Small Cell Squamous Carcinoma">Refractory Lung Non-Small Cell Squamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1769067" ref="tree=MeSH" title="MedGen record for Unresectable Lung Non-Small Cell Squamous Carcinoma">Unresectable Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277444" ref="tree=MeSH" title="MedGen record for Occult Lung Non-Small Cell Carcinoma">Occult Lung Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/78841" ref="tree=MeSH" title="MedGen record for Recurrent Lung Non-Small Cell Carcinoma">Recurrent Lung Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1649140" ref="tree=MeSH" title="MedGen record for Refractory Lung Non-Small Cell Carcinoma">Refractory Lung Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718964" ref="tree=MeSH" title="MedGen record for Resectable Lung Non-Small Cell Carcinoma">Resectable Lung Non-Small Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/56202" ref="tree=MeSH" title="MedGen record for Squamous cell lung carcinoma">Squamous cell lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/318198" ref="tree=MeSH" title="MedGen record for Lung Basaloid Squamous Cell Carcinoma">Lung Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1625078" ref="tree=MeSH" title="MedGen record for Lung Keratinizing Squamous Cell Carcinoma">Lung Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1611891" ref="tree=MeSH" title="MedGen record for Lung Non-Keratinizing Squamous Cell Carcinoma">Lung Non-Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235400" ref="tree=MeSH" title="MedGen record for Lung occult squamous cell carcinoma">Lung occult squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1614560" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma by AJCC v7 Stage">Lung Squamous Cell Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1620963" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Squamous Cell Carcinoma AJCC v6 and v7">Stage 0 Lung Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/208937" ref="tree=MeSH" title="MedGen record for Stage I Lung Squamous Cell Carcinoma AJCC v7">Stage I Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167749" ref="tree=MeSH" title="MedGen record for Stage II Lung Squamous Cell Carcinoma AJCC v7">Stage II Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167750" ref="tree=MeSH" title="MedGen record for Stage III Lung Squamous Cell Carcinoma AJCC v7">Stage III Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1663964" ref="tree=MeSH" title="MedGen record for Stage IV Lung Squamous Cell Carcinoma AJCC v7">Stage IV Lung Squamous Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1625266" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma In Situ">Lung Squamous Cell Carcinoma In Situ</a></span></li><li><span class="TLline"><a href="/medgen/354199" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Small Cell Variant">Lung Squamous Cell Carcinoma, Small Cell Variant</a></span></li><li><span class="TLline"><a href="/medgen/163176" ref="tree=MeSH" title="MedGen record for Metastatic Lung Squamous Cell Carcinoma">Metastatic Lung Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1756132" ref="tree=MeSH" title="MedGen record for Advanced Lung Squamous Cell Carcinoma">Advanced Lung Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163175" ref="tree=MeSH" title="MedGen record for Recurrent Lung Squamous Cell Carcinoma">Recurrent Lung Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1743058" ref="tree=MeSH" title="MedGen record for Refractory Lung Squamous Cell Carcinoma">Refractory Lung Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1651777" ref="tree=MeSH" title="MedGen record for Unresectable Lung Non-Small Cell Carcinoma">Unresectable Lung Non-Small Cell Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_66885"><div><strong>Lung cancer</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66885</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0242379</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">A primary or metastatic malignant neoplasm involving the lung.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/66885">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_66885" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lung cancer</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38684283">Oral targeted therapy for the treatment of non-small cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Phillips WJ,
Leighl NB,
Blais N,
Wheatley-Price P</span><br />
<span class="medgenPMjournal">CMAJ</span>
2024 Apr 28;196(16):E558-E561.
doi: 10.1503/cmaj.231562.
<span class="bold">PMID: </span><a href="/pubmed/38684283" target="_blank">38684283</a><a href="/pmc/articles/PMC11057882" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33435596">Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rybarczyk-Kasiuchnicz A,
Ramlau R,
Stencel K</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2021 Jan 8;22(2)
doi: 10.3390/ijms22020593.
<span class="bold">PMID: </span><a href="/pubmed/33435596" target="_blank">33435596</a><a href="/pmc/articles/PMC7826874" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29183778">Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Osmani L,
Askin F,
Gabrielson E,
Li QK</span><br />
<span class="medgenPMjournal">Semin Cancer Biol</span>
2018 Oct;52(Pt 1):103-109.
Epub 2017 Nov 26
doi: 10.1016/j.semcancer.2017.11.019.
<span class="bold">PMID: </span><a href="/pubmed/29183778" target="_blank">29183778</a><a href="/pmc/articles/PMC5970946" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22non-small%20cell%20lung%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (230)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Non-Small Cell Lung Cancer, 2024</a></h3>
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng122" target="_blank">UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023</a></h3>
<h3 class="nl vspace"><a href="https://www.cms.gov/Medicare/Coverage/DeterminationProcess/downloads/id90TA.pdf" target="_blank">Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin (ARCHIVED)</a></h3>
</div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_114">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Suggested_Reading">Suggested Reading</h1><a sid="114" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed</h3>
<div class="nl"><a target="_blank" href="/pubmed/24673736">National Working Group Meeting on ALK diagnostics in lung cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper W,
Fox S,
O'Toole S,
Morey A,
Frances G,
Pavlakis N,
O'Byrne K,
Dettrick A,
Leong T,
Rathi V,
Spagnolo D,
Hemmings C,
Singh M,
Moffat D,
Tsao MS,
Wilner K,
Buller R,
Pitman Lowenthal S,
Arifeen S,
Binko J,
Alam M</span><br />
<span class="medgenPMjournal">Asia Pac J Clin Oncol</span>
2014 Apr;10 Suppl 2:11-7.
doi: 10.1111/ajco.12190.
<span class="bold">PMID: </span><a href="/pubmed/24673736" target="_blank">24673736</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=" title="PubMed search"></a></div></div>
</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37448121">First-Line Alectinib vs. Brigatinib in Advanced Non-Small Cell Lung Cancer with ALK Rearrangement: Real-World Data.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeon Y,
Park S,
Jung HA,
Sun JM,
Lee SH,
Ahn JS,
Ahn MJ</span><br />
<span class="medgenPMjournal">Cancer Res Treat</span>
2024 Jan;56(1):61-69.
Epub 2023 Jul 14
doi: 10.4143/crt.2023.461.
<span class="bold">PMID: </span><a href="/pubmed/37448121" target="_blank">37448121</a><a href="/pmc/articles/PMC10789949" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34416901">N(6)-methyladenosine-modified circIGF2BP3 inhibits CD8(+) T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Z,
Wang T,
She Y,
Wu K,
Gu S,
Li L,
Dong C,
Chen C,
Zhou Y</span><br />
<span class="medgenPMjournal">Mol Cancer</span>
2021 Aug 20;20(1):105.
doi: 10.1186/s12943-021-01398-4.
<span class="bold">PMID: </span><a href="/pubmed/34416901" target="_blank">34416901</a><a href="/pmc/articles/PMC8377850" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33823116">Machine Learning for Early Lung Cancer Identification Using Routine Clinical and Laboratory Data.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gould MK,
Huang BZ,
Tammemagi MC,
Kinar Y,
Shiff R</span><br />
<span class="medgenPMjournal">Am J Respir Crit Care Med</span>
2021 Aug 15;204(4):445-453.
doi: 10.1164/rccm.202007-2791OC.
<span class="bold">PMID: </span><a href="/pubmed/33823116" target="_blank">33823116</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33435596">Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rybarczyk-Kasiuchnicz A,
Ramlau R,
Stencel K</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2021 Jan 8;22(2)
doi: 10.3390/ijms22020593.
<span class="bold">PMID: </span><a href="/pubmed/33435596" target="_blank">33435596</a><a href="/pmc/articles/PMC7826874" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32883457">Surgery for Locally Advanced and Oligometastatic Non-Small Cell Lung Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coster JN,
Groth SS</span><br />
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
2020 Oct;29(4):543-554.
doi: 10.1016/j.soc.2020.07.001.
<span class="bold">PMID: </span><a href="/pubmed/32883457" target="_blank">32883457</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1446)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38199926">Prognostic and predictive biomarkers in non-small cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Odintsov I,
Sholl LM</span><br />
<span class="medgenPMjournal">Pathology</span>
2024 Mar;56(2):192-204.
Epub 2023 Dec 22
doi: 10.1016/j.pathol.2023.11.006.
<span class="bold">PMID: </span><a href="/pubmed/38199926" target="_blank">38199926</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33823116">Machine Learning for Early Lung Cancer Identification Using Routine Clinical and Laboratory Data.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gould MK,
Huang BZ,
Tammemagi MC,
Kinar Y,
Shiff R</span><br />
<span class="medgenPMjournal">Am J Respir Crit Care Med</span>
2021 Aug 15;204(4):445-453.
doi: 10.1164/rccm.202007-2791OC.
<span class="bold">PMID: </span><a href="/pubmed/33823116" target="_blank">33823116</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29183778">Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Osmani L,
Askin F,
Gabrielson E,
Li QK</span><br />
<span class="medgenPMjournal">Semin Cancer Biol</span>
2018 Oct;52(Pt 1):103-109.
Epub 2017 Nov 26
doi: 10.1016/j.semcancer.2017.11.019.
<span class="bold">PMID: </span><a href="/pubmed/29183778" target="_blank">29183778</a><a href="/pmc/articles/PMC5970946" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25668228">EGFR T790M resistance mutation in non small-cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Denis MG,
Vallée A,
Théoleyre S</span><br />
<span class="medgenPMjournal">Clin Chim Acta</span>
2015 Apr 15;444:81-5.
Epub 2015 Feb 7
doi: 10.1016/j.cca.2015.01.039.
<span class="bold">PMID: </span><a href="/pubmed/25668228" target="_blank">25668228</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25002356">Adenosquamous carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rao N</span><br />
<span class="medgenPMjournal">Semin Diagn Pathol</span>
2014 Jul;31(4):271-7.
Epub 2014 Jun 11
doi: 10.1053/j.semdp.2014.06.004.
<span class="bold">PMID: </span><a href="/pubmed/25002356" target="_blank">25002356</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1450)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/34036692">Pembrolizumab plus pemetrexed-platinum for metastatic nonsquamous non-small-cell lung cancer: KEYNOTE-189 Japan Study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Horinouchi H,
Nogami N,
Saka H,
Nishio M,
Tokito T,
Takahashi T,
Kasahara K,
Hattori Y,
Ichihara E,
Adachi N,
Noguchi K,
Souza F,
Kurata T</span><br />
<span class="medgenPMjournal">Cancer Sci</span>
2021 Aug;112(8):3255-3265.
Epub 2021 Jun 15
doi: 10.1111/cas.14980.
<span class="bold">PMID: </span><a href="/pubmed/34036692" target="_blank">34036692</a><a href="/pmc/articles/PMC8353942" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32530388">Targeting HER2 expression in cancer: New drugs and new indications.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vranić S,
Bešlija S,
Gatalica Z</span><br />
<span class="medgenPMjournal">Bosn J Basic Med Sci</span>
2021 Feb 1;21(1):1-4.
doi: 10.17305/bjbms.2020.4908.
<span class="bold">PMID: </span><a href="/pubmed/32530388" target="_blank">32530388</a><a href="/pmc/articles/PMC7861626" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28499515">Incidence of Pneumonitis With Use of Programmed Death 1 and Programmed Death-Ligand 1 Inhibitors in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis of Trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Khunger M,
Rakshit S,
Pasupuleti V,
Hernandez AV,
Mazzone P,
Stevenson J,
Pennell NA,
Velcheti V</span><br />
<span class="medgenPMjournal">Chest</span>
2017 Aug;152(2):271-281.
Epub 2017 May 10
doi: 10.1016/j.chest.2017.04.177.
<span class="bold">PMID: </span><a href="/pubmed/28499515" target="_blank">28499515</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25996182">Oncolytic viruses: From bench to bedside with a focus on safety.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Buijs PR,
Verhagen JH,
van Eijck CH,
van den Hoogen BG</span><br />
<span class="medgenPMjournal">Hum Vaccin Immunother</span>
2015;11(7):1573-84.
doi: 10.1080/21645515.2015.1037058.
<span class="bold">PMID: </span><a href="/pubmed/25996182" target="_blank">25996182</a><a href="/pmc/articles/PMC4514197" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21730004">Targeted therapy of non-small-cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tiwari D,
Brodie SA,
Brandes JC</span><br />
<span class="medgenPMjournal">Ther Adv Respir Dis</span>
2012 Feb;6(1):41-56.
Epub 2011 Jul 5
doi: 10.1177/1753465811404590.
<span class="bold">PMID: </span><a href="/pubmed/21730004" target="_blank">21730004</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1398)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38979906">Survival and pulmonary function in stage IA non-small cell lung cancer after sublobar resection versus lobectomy: An updated meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mamede I,
Ribeiro L,
Stecca C,
Escalante-Romero L,
Cypel M</span><br />
<span class="medgenPMjournal">J Surg Oncol</span>
2024 Sep;130(3):523-532.
Epub 2024 Jul 9
doi: 10.1002/jso.27767.
<span class="bold">PMID: </span><a href="/pubmed/38979906" target="_blank">38979906</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34154327">Predictive testing in non-small cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dundr P,
Matěj R,
Němejcová K,
Bártů M,
Stružinská I</span><br />
<span class="medgenPMjournal">Klin Onkol</span>
2021 Spring;34(Supplementum 1):29-34.
doi: 10.48095/ccko2021S29.
<span class="bold">PMID: </span><a href="/pubmed/34154327" target="_blank">34154327</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31238096">Exploiting metabolic vulnerabilities of Non small cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Majem B,
Nadal E,
Muñoz-Pinedo C</span><br />
<span class="medgenPMjournal">Semin Cell Dev Biol</span>
2020 Feb;98:54-62.
Epub 2019 Jul 2
doi: 10.1016/j.semcdb.2019.06.004.
<span class="bold">PMID: </span><a href="/pubmed/31238096" target="_blank">31238096</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29183778">Current WHO guidelines and the critical role of immunohistochemical markers in the subclassification of non-small cell lung carcinoma (NSCLC): Moving from targeted therapy to immunotherapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Osmani L,
Askin F,
Gabrielson E,
Li QK</span><br />
<span class="medgenPMjournal">Semin Cancer Biol</span>
2018 Oct;52(Pt 1):103-109.
Epub 2017 Nov 26
doi: 10.1016/j.semcancer.2017.11.019.
<span class="bold">PMID: </span><a href="/pubmed/29183778" target="_blank">29183778</a><a href="/pmc/articles/PMC5970946" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17551011">Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kirson ED,
Dbalý V,
Tovarys F,
Vymazal J,
Soustiel JF,
Itzhaki A,
Mordechovich D,
Steinberg-Shapira S,
Gurvich Z,
Schneiderman R,
Wasserman Y,
Salzberg M,
Ryffel B,
Goldsher D,
Dekel E,
Palti Y</span><br />
<span class="medgenPMjournal">Proc Natl Acad Sci U S A</span>
2007 Jun 12;104(24):10152-7.
Epub 2007 Jun 5
doi: 10.1073/pnas.0702916104.
<span class="bold">PMID: </span><a href="/pubmed/17551011" target="_blank">17551011</a><a href="/pmc/articles/PMC1886002" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1676)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/38199926">Prognostic and predictive biomarkers in non-small cell lung carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Odintsov I,
Sholl LM</span><br />
<span class="medgenPMjournal">Pathology</span>
2024 Mar;56(2):192-204.
Epub 2023 Dec 22
doi: 10.1016/j.pathol.2023.11.006.
<span class="bold">PMID: </span><a href="/pubmed/38199926" target="_blank">38199926</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35501263">Immune checkpoint inhibitor-related thyroid dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Iwama S,
Kobayashi T,
Yasuda Y,
Arima H</span><br />
<span class="medgenPMjournal">Best Pract Res Clin Endocrinol Metab</span>
2022 May;36(3):101660.
Epub 2022 Apr 12
doi: 10.1016/j.beem.2022.101660.
<span class="bold">PMID: </span><a href="/pubmed/35501263" target="_blank">35501263</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31050216">Immunocytochemistry for predictive biomarker testing in lung cancer cytology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jain D,
Nambirajan A,
Borczuk A,
Chen G,
Minami Y,
Moreira AL,
Motoi N,
Papotti M,
Rekhtman N,
Russell PA,
Savic Prince S,
Yatabe Y,
Bubendorf L;
IASLC Pathology Committee</span><br />
<span class="medgenPMjournal">Cancer Cytopathol</span>
2019 May;127(5):325-339.
Epub 2019 May 3
doi: 10.1002/cncy.22137.
<span class="bold">PMID: </span><a href="/pubmed/31050216" target="_blank">31050216</a><a href="/pmc/articles/PMC7493418" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28777143">Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hendry S,
Salgado R,
Gevaert T,
Russell PA,
John T,
Thapa B,
Christie M,
van de Vijver K,
Estrada MV,
Gonzalez-Ericsson PI,
Sanders M,
Solomon B,
Solinas C,
Van den Eynden GGGM,
Allory Y,
Preusser M,
Hainfellner J,
Pruneri G,
Vingiani A,
Demaria S,
Symmans F,
Nuciforo P,
Comerma L,
Thompson EA,
Lakhani S,
Kim SR,
Schnitt S,
Colpaert C,
Sotiriou C,
Scherer SJ,
Ignatiadis M,
Badve S,
Pierce RH,
Viale G,
Sirtaine N,
Penault-Llorca F,
Sugie T,
Fineberg S,
Paik S,
Srinivasan A,
Richardson A,
Wang Y,
Chmielik E,
Brock J,
Johnson DB,
Balko J,
Wienert S,
Bossuyt V,
Michiels S,
Ternes N,
Burchardi N,
Luen SJ,
Savas P,
Klauschen F,
Watson PH,
Nelson BH,
Criscitiello C,
O'Toole S,
Larsimont D,
de Wind R,
Curigliano G,
André F,
Lacroix-Triki M,
van de Vijver M,
Rojo F,
Floris G,
Bedri S,
Sparano J,
Rimm D,
Nielsen T,
Kos Z,
Hewitt S,
Singh B,
Farshid G,
Loibl S,
Allison KH,
Tung N,
Adams S,
Willard-Gallo K,
Horlings HM,
Gandhi L,
Moreira A,
Hirsch F,
Dieci MV,
Urbanowicz M,
Brcic I,
Korski K,
Gaire F,
Koeppen H,
Lo A,
Giltnane J,
Rebelatto MC,
Steele KE,
Zha J,
Emancipator K,
Juco JW,
Denkert C,
Reis-Filho J,
Loi S,
Fox SB</span><br />
<span class="medgenPMjournal">Adv Anat Pathol</span>
2017 Nov;24(6):311-335.
doi: 10.1097/PAP.0000000000000161.
<span class="bold">PMID: </span><a href="/pubmed/28777143" target="_blank">28777143</a><a href="/pmc/articles/PMC5638696" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23885909">Personalized oncology in interventional radiology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abi-Jaoudeh N,
Duffy AG,
Greten TF,
Kohn EC,
Clark TW,
Wood BJ</span><br />
<span class="medgenPMjournal">J Vasc Interv Radiol</span>
2013 Aug;24(8):1083-92; quiz 1093.
doi: 10.1016/j.jvir.2013.04.019.
<span class="bold">PMID: </span><a href="/pubmed/23885909" target="_blank">23885909</a><a href="/pmc/articles/PMC3742380" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1551)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/38979906">Survival and pulmonary function in stage IA non-small cell lung cancer after sublobar resection versus lobectomy: An updated meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mamede I,
Ribeiro L,
Stecca C,
Escalante-Romero L,
Cypel M</span><br />
<span class="medgenPMjournal">J Surg Oncol</span>
2024 Sep;130(3):523-532.
Epub 2024 Jul 9
doi: 10.1002/jso.27767.
<span class="bold">PMID: </span><a href="/pubmed/38979906" target="_blank">38979906</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37216840">Systemic treatment for neuroendocrine non-small cell lung carcinoma: A cases series and a systematic review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jelli B,
Brandão M,
Mekinda Z,
Durieux V,
Berghmans T</span><br />
<span class="medgenPMjournal">Lung Cancer</span>
2023 Jul;181:107232.
Epub 2023 May 10
doi: 10.1016/j.lungcan.2023.107232.
<span class="bold">PMID: </span><a href="/pubmed/37216840" target="_blank">37216840</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34858541">MALAT-1 Expression Correlates with Prognosis in Non-Small-Cell Lung Carcinoma: A Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ran R,
Jin JW,
Zhang WP</span><br />
<span class="medgenPMjournal">Dis Markers</span>
2021;2021:5424623.
Epub 2021 Nov 23
doi: 10.1155/2021/5424623.
<span class="bold">PMID: </span><a href="/pubmed/34858541" target="_blank">34858541</a><a href="/pmc/articles/PMC8632423" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32912754">Oncologic Outcomes of Surgery Versus SBRT for Non-Small-Cell Lung Carcinoma: A Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ijsseldijk MA,
Shoni M,
Siegert C,
Wiering B,
van Engelenburg AKC,
Tsai TC,
Ten Broek RPG,
Lebenthal A</span><br />
<span class="medgenPMjournal">Clin Lung Cancer</span>
2021 May;22(3):e235-e292.
Epub 2020 May 7
doi: 10.1016/j.cllc.2020.04.017.
<span class="bold">PMID: </span><a href="/pubmed/32912754" target="_blank">32912754</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28499515">Incidence of Pneumonitis With Use of Programmed Death 1 and Programmed Death-Ligand 1 Inhibitors in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis of Trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Khunger M,
Rakshit S,
Pasupuleti V,
Hernandez AV,
Mazzone P,
Stevenson J,
Pennell NA,
Velcheti V</span><br />
<span class="medgenPMjournal">Chest</span>
2017 Aug;152(2):271-281.
Epub 2017 May 10
doi: 10.1016/j.chest.2017.04.177.
<span class="bold">PMID: </span><a href="/pubmed/28499515" target="_blank">28499515</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Non-small%20cell%20lung%20carcinoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (48)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (20)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A3%5F23" target="_blank">FISH-interphase (3)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (3)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F12" target="_blank">Microsatellite instability testing (MSI) (2)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (3)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (9)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (25)</a></li>
<li><a href="/gtr/tests?term=C0007131%5bDISCUI%5d&amp;filter=method%3A2%5F19" target="_blank">Targeted variant analysis (19)</a></li>
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0007131%5bDISCUI%5d" target="_blank">See all (58)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=488201" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Non-small%20cell%20lung%20carcinoma" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22non-small%20cell%20lung%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Non-small%20cell%20lung%20carcinoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/nscl.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Non-Small Cell Lung Cancer, 2024</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng122">NICE, 2023</a><div>UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023</div></li><li><a target="_blank" href="https://www.cms.gov/Medicare/Coverage/DeterminationProcess/downloads/id90TA.pdf">AHRQ, 2013</a><div>Technology Assessment on Genetic Testing or Molecular Pathology Testing of Cancers with Unknown Primary Site to Determine Origin (ARCHIVED)</div></li></ul></div>
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