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<meta name="keywords" content="C1295607, decreased plasma tsh, decreased thyroid stimulating hormone level, decreased thyroid-stimulating hormone level, decreased thyrotropin level, finding, thyroid stimulating hormone level below reference range, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Reduced amount of the thyroid-stimulating hormone (TSH), which is produced by the anterior pituitary gland and stimulates the function of the thyroid gland." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=717708
|
||
ConceptID=C1295607
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Decreased thyroid-stimulating hormone level</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>717708</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1295607</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Decreased plasma TSH; Decreased thyroid stimulating hormone level; Decreased thyrotropin level; Thyroid stimulating hormone level below reference range</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Decreased thyroid stimulating hormone level (131017004); Thyroid stimulating hormone level below reference range (131017004)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0031098">HP:0031098</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Reduced amount of the thyroid-stimulating hormone (TSH), which is produced by the anterior pituitary gland and stimulates the function of the thyroid gland. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Decreased thyroid-stimulating hormone level</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/893021" ref="tree=MeSH" title="MedGen record for Abnormality of the endocrine system">Abnormality of the endocrine system</a></span><ul><li><span class="TLline"><a href="/medgen/871176" ref="tree=MeSH" title="MedGen record for Abnormal circulating hormone concentration">Abnormal circulating hormone concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1384219" ref="tree=MeSH" title="MedGen record for Abnormal thyroid-stimulating hormone level">Abnormal thyroid-stimulating hormone level</a></span><ul><li><span class="matched_ds">Decreased thyroid-stimulating hormone level</span></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_78786"><div><strong>Isolated thyroid-stimulating hormone deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>78786</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0271789</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A type of central congenital hypothyroidism, a permanent thyroid deficiency that is present from birth, characterized by low levels of thyroid hormones due to a deficiency in TSH synthesis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/78786">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_209236"><div><strong>Pituitary hormone deficiency, combined, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>209236</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0878683</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">PROP1-related combined pituitary hormone deficiency (CPHD) is associated with deficiencies of: growth hormone (GH); thyroid-stimulating hormone (TSH); the two gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH); prolactin (PrL); and occasionally adrenocorticotropic hormone (ACTH). At birth, in contrast to individuals with congenital CPHD of other etiologies, neonates with PROP1-related CPHD lack perinatal signs of hypopituitarism. Mean birth weights and lengths are usually within the normal range and neonatal hypoglycemia and prolonged neonatal jaundice are not prevalent findings. Most affected individuals are ascertained because of short stature during childhood. Although TSH deficiency can present shortly after birth, TSH deficiency usually occurs with or after the onset of GH deficiency. Hypothyroidism is usually mild. FSH and LH deficiencies are typically identified at the age of onset of puberty. Affected individuals can have absent or delayed and incomplete secondary sexual development with infertility. Untreated males usually have a small penis and small testes. Some females experience menarche but subsequently require hormone replacement therapy. ACTH deficiency is less common and, when present, usually occurs in adolescence or adulthood. Neuroimaging of hypothalamic-pituitary region usually demonstrates a hypoplastic or normal anterior pituitary lobe and a normal posterior pituitary lobe.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/209236">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_373154"><div><strong>Familial hyperthyroidism due to mutations in TSH receptor</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>373154</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1836706</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare hyperthyroidism characterized by mild to severe hyperthyroidism, presence of goiter, absence of features of autoimmunity, frequent relapses while on treatment and a positive family history.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/373154">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_341307"><div><strong>Graves disease, susceptibility to, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341307</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1848795</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Graves disease (GRD) is an autoimmune disorder in which antibodies to the thyrotropin receptor (TSHR; 603372) result in constitutive activation of the receptor and increased levels of thyroid hormone. Wilkin (1990) reviewed endocrine disorders of hormone excess and hormone deficiency resulting from receptor autoimmunity. Genetic Heterogeneity of Graves Disease Susceptibility to Graves disease-1 (GRD1) has been mapped to chromosome 14q31. Other susceptibility loci for Graves disease include GRD2 (603388) on chromosome 20q13, GRDX1 (300351) on Xp11, and GRDX2 (see 300351) on Xq21.33-q22. Graves disease has also been mapped to several loci that confer susceptibility to autoimmune thyroid diseases, including Hashimoto thyroiditis (HT; 140300): AITD1 (608173) on 6p11; AITD2 (608174) on 5q31-q33; AITD3 (608175) on 8q24; AITD4 (608176) on 10q, and AITD5 (601941) on 18q21.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/341307">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_355106"><div><strong>Familial gestational hyperthyroidism</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355106</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1863959</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Some degree of stimulation of the thyroid gland by chorionic gonadotropin (see 118860) is common during early pregnancy. When serum chorionic gonadotropin concentrations are abnormally high, e.g., in women with molar pregnancies (231090), overt hyperthyroidism may ensue. The pathophysiologic mechanism appears to be promiscuous stimulation of the thyrotropin receptor by the excess chorionic gonadotropin. The explanation for this stimulation is the close structural relations between chorionic gonadotropin and thyrotropin and between their receptors (Grossmann et al., 1997).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/355106">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_413851"><div><strong>Thyrotoxic periodic paralysis, susceptibility to, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>413851</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2750473</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any thyrotoxic periodic paralysis in which the cause of the disease is a mutation in the KCNJ18 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/413851">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_414421"><div><strong>Pituitary hormone deficiency, combined, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>414421</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2751608</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Combined pituitary hormone deficiency (CPHD) in man denotes impaired production of growth hormone (GH; 139250) and one or more of the other 5 anterior pituitary hormones. Mutations of the POU1F1 gene in the human and Pit1 in the mouse are responsible for pleiotropic deficiencies of GH, prolactin (PRL; 176760), and thyroid-stimulating hormone (TSH; see 188540), while the production of adrenocorticotrophic hormone (ACTH; see 176830), luteinizing hormone (LH; 152780), and follicle-stimulating hormone (FSH; 136530) are preserved (Wu et al., 1998). Some patients exhibit only GH deficiency, although approximately 50% of isolated GH deficiency progresses to CPHD (Gergics et al., 2021). In infancy severe growth deficiency from birth as well as distinctive facial features with prominent forehead, marked midfacial hypoplasia with depressed nasal bridge, deep-set eyes, and a short nose with anteverted nostrils and hypoplastic pituitary gland by MRI examination can be seen (Aarskog et al., 1997). Some cases present with severe mental retardation along with short stature (Radovick et al., 1992). Reviews Voss and Rosenfeld (1992) reviewed the development and differentiation of the 5 pituitary cell types: galactotropes, gonadotropes, corticotropes, thyrotropes, and somatotropes. As indicated by the mutations in PIT1 described later, combined pituitary hormone deficiency can have either autosomal dominant or autosomal recessive inheritance, depending on the part of the PIT1 molecule affected by the mutation. Some mutations have a dominant-negative effect. Genetic Heterogeneity of Combined Pituitary Hormone Deficiency CPHD2 (262600), associated with hypogonadism, is caused by mutation in the PROP1 gene (601538). CPHD3 (221750), which is associated with rigid cervical spine and variable sensorineural deafness, is caused by mutation in the LHX3 gene (600577). CPHD4 (262700) is caused by mutation in the LHX4 gene (602146). CPHD5 (see septooptic dysplasia, 182230) is caused by mutation in the HESX1 gene (601802). CPHD6 (613986) is caused by mutation in the OTX2 gene (600037). CPHD7 (618160) is caused by mutation in the RNPC3 gene (618016). CPHD8 (620303) is caused by mutation in the ROBO1 gene (602430).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/414421">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462790"><div><strong>Pituitary hormone deficiency, combined, 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462790</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151440</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any combined pituitary hormone deficiencies, genetic form in which the cause of the disease is a mutation in the OTX2 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462790">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1785671"><div><strong>BDV syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1785671</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543403</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">BDV syndrome (BDVS) is an autosomal recessive disorder characterized by early-onset profound obesity, hyperphagia, and moderately impaired intellectual development accompanied by infantile hypotonia and other endocrine disorders including hypogonadotropic hypogonadism, hypothyroidism, and insulin resistance (summary by Bosch et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1785671">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1841011"><div><strong>Pituitary hormone deficiency, combined or isolated, 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1841011</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5830375</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Combined pituitary hormone deficiency-8 (CPHD8) is an autosomal dominant disorder characterized by deficiency of one or more of the pituitary hormones. Affected individuals have short stature due to growth hormone (GH; 139250) deficiency with variable deficiencies of other pituitary hormones, including TSH (see 188540), ACTH, and LH/FSH (see 118850). Posterior pituitary deficiency leading to central diabetes insipidus is rare (Bashamboo et al., 2017). Many patients are diagnosed with 'pituitary stalk interruption syndrome' (PSIS), which is characterized by a thin or absent pituitary stalk, absent or ectopic posterior pituitary, and hypoplasia of the anterior pituitary demonstrated on brain imaging, although this classic triad may be incomplete. Brauner et al. (2020) noted the complex phenotypic and genetic heterogeneity of PSIS, and concluded that it is a feature of genetic disorders or syndromes rather than a specific clinical entity. For a discussion of genetic heterogeneity of combined pituitary hormone deficiency, see CPHD1 (613038).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1841011">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1845412"><div><strong>Diabetes, deafness, developmental delay, and short stature syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1845412</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882732</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Diabetes, deafness, developmental delay, and short stature syndrome (DDDS) is characterized by childhood-onset autoantibody-negative diabetes mellitus and bilateral sensorineural deafness, as well as short stature, microcephaly, and developmental delay (Montaser et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1845412">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1785671" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">BDV syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1845412" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Diabetes, deafness, developmental delay, and short stature syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355106" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial gestational hyperthyroidism</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_373154" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hyperthyroidism due to mutations in TSH receptor</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_341307" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Graves disease, susceptibility to, 1</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (11)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_78786" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Isolated thyroid-stimulating hormone deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1841011" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pituitary hormone deficiency, combined or isolated, 8</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_414421" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pituitary hormone deficiency, combined, 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_209236" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pituitary hormone deficiency, combined, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462790" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pituitary hormone deficiency, combined, 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_413851" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thyrotoxic periodic paralysis, susceptibility to, 2</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34040582">The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Benvenga S,
|
||
Nordio M,
|
||
Laganà AS,
|
||
Unfer V</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2021;12:662582.
|
||
Epub 2021 May 10
|
||
doi: 10.3389/fendo.2021.662582.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34040582" target="_blank">34040582</a><a href="/pmc/articles/PMC8143049" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26980880">Management of Neonates Born to Mothers With Graves' Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">van der Kaay DC,
|
||
Wasserman JD,
|
||
Palmert MR</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2016 Apr;137(4)
|
||
Epub 2016 Mar 15
|
||
doi: 10.1542/peds.2015-1878.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26980880" target="_blank">26980880</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23939500">Amenorrhea: an approach to diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Klein DA,
|
||
Poth MA</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2013 Jun 1;87(11):781-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23939500" target="_blank">23939500</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(decreased%20thyroid-stimulating%20hormone%20level)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (217)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36835005">Vitamin D and the Thyroid: A Critical Review of the Current Evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Babić Leko M,
|
||
Jureško I,
|
||
Rozić I,
|
||
Pleić N,
|
||
Gunjača I,
|
||
Zemunik T</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2023 Feb 10;24(4)
|
||
doi: 10.3390/ijms24043586.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36835005" target="_blank">36835005</a><a href="/pmc/articles/PMC9964959" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35837308">Myoinositol in Autoimmune Thyroiditis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Paparo SR,
|
||
Ferrari SM,
|
||
Patrizio A,
|
||
Elia G,
|
||
Ragusa F,
|
||
Botrini C,
|
||
Balestri E,
|
||
Guarneri F,
|
||
Benvenga S,
|
||
Antonelli A,
|
||
Fallahi P</span><br />
|
||
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
|
||
2022;13:930756.
|
||
Epub 2022 Jun 28
|
||
doi: 10.3389/fendo.2022.930756.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35837308" target="_blank">35837308</a><a href="/pmc/articles/PMC9273877" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35440339">Role of Dietary Supplements in Thyroid Diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dahiya V,
|
||
Vasudeva N,
|
||
Sharma S,
|
||
Kumar A</span><br />
|
||
<span class="medgenPMjournal">Endocr Metab Immune Disord Drug Targets</span>
|
||
2022;22(10):985-996.
|
||
doi: 10.2174/1871530322666220419125131.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35440339" target="_blank">35440339</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31894080">Thyroid Function During the Fetal and Neonatal Periods.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eng L,
|
||
Lam L</span><br />
|
||
<span class="medgenPMjournal">Neoreviews</span>
|
||
2020 Jan;21(1):e30-e36.
|
||
doi: 10.1542/neo.21-1-e30.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31894080" target="_blank">31894080</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31287527">Subclinical Hypothyroidism: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Biondi B,
|
||
Cappola AR,
|
||
Cooper DS</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2019 Jul 9;322(2):153-160.
|
||
doi: 10.1001/jama.2019.9052.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31287527" target="_blank">31287527</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2031)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37831130">Impaired Sensitivity to Thyroid Hormones Is Associated With Decreased Vitamin D Levels in the Euthyroid Population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li Y,
|
||
Sun J,
|
||
Jiao Y,
|
||
Li N,
|
||
Zhao W</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2024 Feb 20;109(3):691-700.
|
||
doi: 10.1210/clinem/dgad607.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37831130" target="_blank">37831130</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32975922">Subclinical hypothyroidism in pregnancy: controversies on diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gietka-Czernel M,
|
||
Glinicki P</span><br />
|
||
<span class="medgenPMjournal">Pol Arch Intern Med</span>
|
||
2021 Mar 30;131(3):266-275.
|
||
Epub 2020 Sep 25
|
||
doi: 10.20452/pamw.15626.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32975922" target="_blank">32975922</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31894080">Thyroid Function During the Fetal and Neonatal Periods.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eng L,
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<div class="nl"><a target="_blank" href="/pubmed/28724185">Myo-inositol plus selenium supplementation restores euthyroid state in Hashimoto's patients with subclinical hypothyroidism.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Nordio M,
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<span class="medgenPMjournal">Eur Rev Med Pharmacol Sci</span>
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2017 Jun;21(2 Suppl):51-59.
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<div class="nl"><a target="_blank" href="/pubmed/20537182">Congenital hypothyroidism.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Rastogi MV,
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LaFranchi SH</span><br />
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<span class="bold">PMID: </span><a href="/pubmed/20537182" target="_blank">20537182</a><a href="/pmc/articles/PMC2903524" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1107)</a></div><h3 class="subhead">Therapy</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38243784">Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.</a></div>
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Maissen-Abgottspon S,
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Stanga Z,
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Mühlebach S,
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Trepp R,
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Bally L,
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Bano A</span><br />
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<span class="medgenPMjournal">Thyroid</span>
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Epub 2024 Feb 16
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doi: 10.1089/thy.2023.0556.
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<span class="bold">PMID: </span><a href="/pubmed/38243784" target="_blank">38243784</a><a href="/pmc/articles/PMC10951571" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35837308">Myoinositol in Autoimmune Thyroiditis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Paparo SR,
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Ferrari SM,
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Patrizio A,
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Elia G,
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<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
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2022;13:930756.
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Epub 2022 Jun 28
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<span class="bold">PMID: </span><a href="/pubmed/35837308" target="_blank">35837308</a><a href="/pmc/articles/PMC9273877" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/35440339">Role of Dietary Supplements in Thyroid Diseases.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Dahiya V,
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Vasudeva N,
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Sharma S,
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Kumar A</span><br />
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<span class="medgenPMjournal">Endocr Metab Immune Disord Drug Targets</span>
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doi: 10.2174/1871530322666220419125131.
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<span class="bold">PMID: </span><a href="/pubmed/35440339" target="_blank">35440339</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/31287527">Subclinical Hypothyroidism: A Review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Biondi B,
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Cappola AR,
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Cooper DS</span><br />
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<span class="medgenPMjournal">JAMA</span>
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2019 Jul 9;322(2):153-160.
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doi: 10.1001/jama.2019.9052.
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<span class="bold">PMID: </span><a href="/pubmed/31287527" target="_blank">31287527</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/22191793">Overt and subclinical hypothyroidism: who to treat and how.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Khandelwal D,
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Tandon N</span><br />
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doi: 10.2165/11598070-000000000-00000.
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<span class="bold">PMID: </span><a href="/pubmed/22191793" target="_blank">22191793</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1771)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38900813">Vitamin D and thyroid function: A mendelian randomization study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Pleić N,
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Babić Leko M,
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Gunjača I,
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Zemunik T</span><br />
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<span class="medgenPMjournal">PLoS One</span>
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<span class="bold">PMID: </span><a href="/pubmed/38900813" target="_blank">38900813</a><a href="/pmc/articles/PMC11189194" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/36658102">Association of Thyroid-Stimulating Hormone With All-Cause Mortality: A 2-Sample Mendelian Randomization Study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gu Y,
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Song Z,
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Li Q,
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Wang J,
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Song Y,
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Meng G,
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Wu H,
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Zhang S,
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Wang X,
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Zhang J,
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Lu X,
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Liu Q,
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Huang T,
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Yang J,
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Niu K</span><br />
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<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
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2023 Jun 16;108(7):e396-e403.
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doi: 10.1210/clinem/dgad025.
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<span class="bold">PMID: </span><a href="/pubmed/36658102" target="_blank">36658102</a></div>
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|
||
<div class="nl"><a target="_blank" href="/pubmed/33899528">Thyroid Function and Mood Disorders: A Mendelian Randomization Study.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kuś A,
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Kjaergaard AD,
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Marouli E,
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Del Greco M F,
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Sterenborg RBTM,
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Chaker L,
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Peeters RP,
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Bednarczuk T,
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Åsvold BO,
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Burgess S,
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Deloukas P,
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Teumer A,
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Ellervik C,
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Medici M</span><br />
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<span class="medgenPMjournal">Thyroid</span>
|
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2021 Aug;31(8):1171-1181.
|
||
Epub 2021 May 26
|
||
doi: 10.1089/thy.2020.0884.
|
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<span class="bold">PMID: </span><a href="/pubmed/33899528" target="_blank">33899528</a><a href="/pmc/articles/PMC7612998" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33548002">Thyroid function, sex hormones and sexual function: a Mendelian randomization study.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Kjaergaard AD,
|
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Marouli E,
|
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Papadopoulou A,
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Deloukas P,
|
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Kuś A,
|
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Sterenborg R,
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Teumer A,
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Burgess S,
|
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Åsvold BO,
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Chasman DI,
|
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Medici M,
|
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Ellervik C</span><br />
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<span class="medgenPMjournal">Eur J Epidemiol</span>
|
||
2021 Mar;36(3):335-344.
|
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Epub 2021 Feb 6
|
||
doi: 10.1007/s10654-021-00721-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33548002" target="_blank">33548002</a><a href="/pmc/articles/PMC7612952" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20537182">Congenital hypothyroidism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rastogi MV,
|
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LaFranchi SH</span><br />
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<span class="medgenPMjournal">Orphanet J Rare Dis</span>
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2010 Jun 10;5:17.
|
||
doi: 10.1186/1750-1172-5-17.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20537182" target="_blank">20537182</a><a href="/pmc/articles/PMC2903524" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (717)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/36835005">Vitamin D and the Thyroid: A Critical Review of the Current Evidence.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Babić Leko M,
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Jureško I,
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Rozić I,
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Pleić N,
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Gunjača I,
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Zemunik T</span><br />
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<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2023 Feb 10;24(4)
|
||
doi: 10.3390/ijms24043586.
|
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<span class="bold">PMID: </span><a href="/pubmed/36835005" target="_blank">36835005</a><a href="/pmc/articles/PMC9964959" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35440339">Role of Dietary Supplements in Thyroid Diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dahiya V,
|
||
Vasudeva N,
|
||
Sharma S,
|
||
Kumar A</span><br />
|
||
<span class="medgenPMjournal">Endocr Metab Immune Disord Drug Targets</span>
|
||
2022;22(10):985-996.
|
||
doi: 10.2174/1871530322666220419125131.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35440339" target="_blank">35440339</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34204586">Environmental Factors Affecting Thyroid-Stimulating Hormone and Thyroid Hormone Levels.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Babić Leko M,
|
||
Gunjača I,
|
||
Pleić N,
|
||
Zemunik T</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2021 Jun 17;22(12)
|
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doi: 10.3390/ijms22126521.
|
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<span class="bold">PMID: </span><a href="/pubmed/34204586" target="_blank">34204586</a><a href="/pmc/articles/PMC8234807" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33548002">Thyroid function, sex hormones and sexual function: a Mendelian randomization study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kjaergaard AD,
|
||
Marouli E,
|
||
Papadopoulou A,
|
||
Deloukas P,
|
||
Kuś A,
|
||
Sterenborg R,
|
||
Teumer A,
|
||
Burgess S,
|
||
Åsvold BO,
|
||
Chasman DI,
|
||
Medici M,
|
||
Ellervik C</span><br />
|
||
<span class="medgenPMjournal">Eur J Epidemiol</span>
|
||
2021 Mar;36(3):335-344.
|
||
Epub 2021 Feb 6
|
||
doi: 10.1007/s10654-021-00721-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33548002" target="_blank">33548002</a><a href="/pmc/articles/PMC7612952" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31287527">Subclinical Hypothyroidism: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Biondi B,
|
||
Cappola AR,
|
||
Cooper DS</span><br />
|
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<span class="medgenPMjournal">JAMA</span>
|
||
2019 Jul 9;322(2):153-160.
|
||
doi: 10.1001/jama.2019.9052.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31287527" target="_blank">31287527</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1458)</a></div></div>
|
||
</div>
|
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|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38368537">Effects of Levothyroxine Treatment on Fertility and Pregnancy Outcomes in Subclinical Hypothyroidism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sankoda A,
|
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Suzuki H,
|
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Imaizumi M,
|
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Yoshihara A,
|
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Kobayashi S,
|
||
Katai M,
|
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Hamada K,
|
||
Hidaka Y,
|
||
Yoshihara A,
|
||
Nakamura H,
|
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Kubota S,
|
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Kakita-Kobayashi M,
|
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Iwase A,
|
||
Sugiyama T,
|
||
Ota E,
|
||
Arata N</span><br />
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<span class="medgenPMjournal">Thyroid</span>
|
||
2024 Apr;34(4):519-530.
|
||
doi: 10.1089/thy.2023.0546.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38368537" target="_blank">38368537</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38243784">Selenium Supplementation in Patients with Hashimoto Thyroiditis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huwiler VV,
|
||
Maissen-Abgottspon S,
|
||
Stanga Z,
|
||
Mühlebach S,
|
||
Trepp R,
|
||
Bally L,
|
||
Bano A</span><br />
|
||
<span class="medgenPMjournal">Thyroid</span>
|
||
2024 Mar;34(3):295-313.
|
||
Epub 2024 Feb 16
|
||
doi: 10.1089/thy.2023.0556.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38243784" target="_blank">38243784</a><a href="/pmc/articles/PMC10951571" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38206745">Effects of vitamin D supplementation on autoantibodies and thyroid function in patients with Hashimoto's thyroiditis: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tang J,
|
||
Shan S,
|
||
Li F,
|
||
Yun P</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2023 Dec 29;102(52):e36759.
|
||
doi: 10.1097/MD.0000000000036759.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38206745" target="_blank">38206745</a><a href="/pmc/articles/PMC10754614" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36772983">Association between bisphenol A exposure and thyroid dysfunction in adults: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan S,
|
||
Du X,
|
||
Liu H,
|
||
Guo X,
|
||
Zhang B,
|
||
Wang Y,
|
||
Wang B,
|
||
Zhang H,
|
||
Guo H</span><br />
|
||
<span class="medgenPMjournal">Toxicol Ind Health</span>
|
||
2023 Apr;39(4):188-203.
|
||
Epub 2023 Feb 11
|
||
doi: 10.1177/07482337231156284.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36772983" target="_blank">36772983</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34274416">Thyroid hormones in persons with schizophrenia: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Misiak B,
|
||
Stańczykiewicz B,
|
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Wiśniewski M,
|
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Bartoli F,
|
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Carra G,
|
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Cavaleri D,
|
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Samochowiec J,
|
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Jarosz K,
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Rosińczuk J,
|
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Frydecka D</span><br />
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<span class="medgenPMjournal">Prog Neuropsychopharmacol Biol Psychiatry</span>
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2021 Dec 20;111:110402.
|
||
Epub 2021 Jul 15
|
||
doi: 10.1016/j.pnpbp.2021.110402.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34274416" target="_blank">34274416</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20thyroid-stimulating%20hormone%20level%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (42)</a></div></div>
|
||
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|
||
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|
||
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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