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1048 lines
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<!--
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||
UID=43225
|
||
ConceptID=C0085669
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Acute leukemia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>43225</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0085669</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Acute leukemias</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Acute leukemia (91855006); Acute leukemia, morphology, including blast cell OR undifferentiated leukemia (24072005); Acute leukemia, disease (91855006); Acute leukemia (24072005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002488">HP:0002488</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0010643" target="_blank">MONDO:0010643</a></td></tr>
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||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">A clonal (malignant) hematopoietic disorder with an acute onset, affecting the bone marrow and the peripheral blood. The malignant cells show minimal differentiation and are called blasts, either myeloid blasts (myeloblasts) or lymphoid blasts (lymphoblasts). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0085669[DISCUI]&test_type=Clinical" ref="ncbi_uid=43225">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Acute leukemia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/208860" ref="tree=MeSH" title="MedGen record for Hematopoietic and Lymphatic System Disorder">Hematopoietic and Lymphatic System Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/5483" ref="tree=MeSH" title="MedGen record for Hematologic disorder">Hematologic disorder</a></span><ul><li><span class="TLline"><a href="/medgen/138213" ref="tree=MeSH" title="MedGen record for Hematologic neoplasm">Hematologic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/9725" ref="tree=MeSH" title="MedGen record for Leukemia">Leukemia</a></span><ul><li><span class="matched_ds">Acute leukemia</span><ul><li><span class="TLline"><a href="/medgen/7318" ref="tree=MeSH" title="MedGen record for Acute biphenotypic leukemia">Acute biphenotypic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/926425" ref="tree=MeSH" title="MedGen record for Infant Acute Biphenotypic Leukemia">Infant Acute Biphenotypic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1641256" ref="tree=MeSH" title="MedGen record for Recurrent Acute Biphenotypic Leukemia">Recurrent Acute Biphenotypic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1731320" ref="tree=MeSH" title="MedGen record for Refractory Acute Biphenotypic Leukemia">Refractory Acute Biphenotypic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/226983" ref="tree=MeSH" title="MedGen record for Acute leukemia of ambiguous lineage">Acute leukemia of ambiguous lineage</a></span><ul><li><span class="TLline"><a href="/medgen/1666838" ref="tree=MeSH" title="MedGen record for Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified">Acute Leukemia of Ambiguous Lineage, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/79081" ref="tree=MeSH" title="MedGen record for Acute undifferentiated leukemia">Acute undifferentiated leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/926424" ref="tree=MeSH" title="MedGen record for Infant Acute Undifferentiated Leukemia">Infant Acute Undifferentiated Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1640402" ref="tree=MeSH" title="MedGen record for Recurrent Acute Undifferentiated Leukemia">Recurrent Acute Undifferentiated Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1741970" ref="tree=MeSH" title="MedGen record for Refractory Acute Undifferentiated Leukemia">Refractory Acute Undifferentiated Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/417342" ref="tree=MeSH" title="MedGen record for Mixed phenotype acute leukemia">Mixed phenotype acute leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/87614" ref="tree=MeSH" title="MedGen record for Acute bilineal leukemia">Acute bilineal leukemia</a></span></li><li><span class="TLline"><a href="/medgen/414807" ref="tree=MeSH" title="MedGen record for Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)">Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)</a></span></li><li><span class="TLline"><a href="/medgen/443130" ref="tree=MeSH" title="MedGen record for Mixed phenotype acute leukemia with t(v;11q23.3)">Mixed phenotype acute leukemia with t(v;11q23.3)</a></span></li><li><span class="TLline"><a href="/medgen/501146" ref="tree=MeSH" title="MedGen record for Mixed phenotype acute leukemia, B/myeloid">Mixed phenotype acute leukemia, B/myeloid</a></span></li><li><span class="TLline"><a href="/medgen/1661586" ref="tree=MeSH" title="MedGen record for Mixed Phenotype Acute Leukemia, Rare Types">Mixed Phenotype Acute Leukemia, Rare Types</a></span></li><li><span class="TLline"><a href="/medgen/443132" ref="tree=MeSH" title="MedGen record for Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified">Mixed Phenotype Acute Leukemia, T/Myeloid, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/1665335" ref="tree=MeSH" title="MedGen record for Recurrent Mixed Phenotype Acute Leukemia">Recurrent Mixed Phenotype Acute Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1648912" ref="tree=MeSH" title="MedGen record for Refractory Mixed Phenotype Acute Leukemia">Refractory Mixed Phenotype Acute Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1747716" ref="tree=MeSH" title="MedGen record for Recurrent Acute Leukemia of Ambiguous Lineage">Recurrent Acute Leukemia of Ambiguous Lineage</a></span></li><li><span class="TLline"><a href="/medgen/1751423" ref="tree=MeSH" title="MedGen record for Refractory Acute Leukemia of Ambiguous Lineage">Refractory Acute Leukemia of Ambiguous Lineage</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7317" ref="tree=MeSH" title="MedGen record for Acute lymphoid leukemia">Acute lymphoid leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/890737" ref="tree=MeSH" title="MedGen record for Acute Lymphoblastic Leukemia by Gene Expression Profile">Acute Lymphoblastic Leukemia by Gene Expression Profile</a></span><ul><li><span class="TLline"><a href="/medgen/881413" ref="tree=MeSH" title="MedGen record for Acute Lymphoblastic Leukemia by ROSE Cluster">Acute Lymphoblastic Leukemia by ROSE Cluster</a></span></li><li><span class="TLline"><a href="/medgen/887378" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia, BCR-ABL1-Like">B Acute Lymphoblastic Leukemia, BCR-ABL1-Like</a></span></li><li><span class="TLline"><a href="/medgen/890499" ref="tree=MeSH" title="MedGen record for DDIT4L Acute Lymphoblastic Leukemia">DDIT4L Acute Lymphoblastic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/199693" ref="tree=MeSH" title="MedGen record for Adult acute lymphoblastic leukemia">Adult acute lymphoblastic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/79010" ref="tree=MeSH" title="MedGen record for B-cell adult acute lymphocytic leukemia">B-cell adult acute lymphocytic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/124510" ref="tree=MeSH" title="MedGen record for Recurrent Adult Acute Lymphoblastic Leukemia">Recurrent Adult Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/925834" ref="tree=MeSH" title="MedGen record for Refractory Adult Acute Lymphoblastic Leukemia">Refractory Adult Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/79009" ref="tree=MeSH" title="MedGen record for T-cell adult acute lymphocytic leukemia">T-cell adult acute lymphocytic leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/231365" ref="tree=MeSH" title="MedGen record for Aleukemic Acute Lymphoblastic Leukemia">Aleukemic Acute Lymphoblastic Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/231366" ref="tree=MeSH" title="MedGen record for Aleukemic Acute Lymphoblastic Leukemia Cutis">Aleukemic Acute Lymphoblastic Leukemia Cutis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/226949" ref="tree=MeSH" title="MedGen record for B-cell acute lymphoblastic leukemia">B-cell acute lymphoblastic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1374530" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21">B Acute Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21</a></span></li><li><span class="TLline"><a href="/medgen/396855" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia with t(12;21)(p13.2;q22.1); ETV6-RUNX1">B Acute Lymphoblastic Leukemia with t(12;21)(p13.2;q22.1); ETV6-RUNX1</a></span></li><li><span class="TLline"><a href="/medgen/396856" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia with t(1;19)(q23;p13.3); TCF3-PBX1">B Acute Lymphoblastic Leukemia with t(1;19)(q23;p13.3); TCF3-PBX1</a></span></li><li><span class="TLline"><a href="/medgen/437495" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia with t(5;14)(q31.1;q32.3); IL3-IGH">B Acute Lymphoblastic Leukemia with t(5;14)(q31.1;q32.3); IL3-IGH</a></span></li><li><span class="TLline"><a href="/medgen/397153" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia with t(v;11q23.3); KMT2A Rearranged">B Acute Lymphoblastic Leukemia with t(v;11q23.3); KMT2A Rearranged</a></span></li><li><span class="TLline"><a href="/medgen/927478" ref="tree=MeSH" title="MedGen record for B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative">B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative</a></span></li><li><span class="TLline"><a href="/medgen/83526" ref="tree=MeSH" title="MedGen record for B-cell childhood acute lymphoblastic leukemia">B-cell childhood acute lymphoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/394941" ref="tree=MeSH" title="MedGen record for Hyperdiploid B Acute Lymphoblastic Leukemia">Hyperdiploid B Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/394638" ref="tree=MeSH" title="MedGen record for Hypodiploid B Acute Lymphoblastic Leukemia">Hypodiploid B Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/313581" ref="tree=MeSH" title="MedGen record for Ph-positive acute lymphoblastic leukemia">Ph-positive acute lymphoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1634726" ref="tree=MeSH" title="MedGen record for Recurrent B Acute Lymphoblastic Leukemia">Recurrent B Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1636080" ref="tree=MeSH" title="MedGen record for Refractory B Acute Lymphoblastic Leukemia">Refractory B Acute Lymphoblastic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/44122" ref="tree=MeSH" title="MedGen record for Childhood acute lymphoblastic leukemia">Childhood acute lymphoblastic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/83527" ref="tree=MeSH" title="MedGen record for Adult L1 Acute Lymphoblastic Leukemia">Adult L1 Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/852470" ref="tree=MeSH" title="MedGen record for Childhood L1 Acute Lymphoblastic Leukemia">Childhood L1 Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/889772" ref="tree=MeSH" title="MedGen record for Infant Acute Lymphoblastic Leukemia">Infant Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/75831" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Acute Lymphoblastic Leukemia">Recurrent Childhood Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/889646" ref="tree=MeSH" title="MedGen record for Refractory Childhood Acute Lymphoblastic Leukemia">Refractory Childhood Acute Lymphoblastic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/75996" ref="tree=MeSH" title="MedGen record for T-cell childhood acute lymphocytic leukemia">T-cell childhood acute lymphocytic leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83896" ref="tree=MeSH" title="MedGen record for Precursor B-cell acute lymphoblastic leukemia">Precursor B-cell acute lymphoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/976286" ref="tree=MeSH" title="MedGen record for Precursor T-cell acute lymphoblastic leukemia">Precursor T-cell acute lymphoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1632670" ref="tree=MeSH" title="MedGen record for Recurrent Acute Lymphoblastic Leukemia">Recurrent Acute Lymphoblastic Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1626864" ref="tree=MeSH" title="MedGen record for Recurrent B Acute Lymphoblastic Leukemia, BCR-ABL1-Like">Recurrent B Acute Lymphoblastic Leukemia, BCR-ABL1-Like</a></span></li><li><span class="TLline"><a href="/medgen/1661578" ref="tree=MeSH" title="MedGen record for Recurrent T Acute Lymphoblastic Leukemia">Recurrent T Acute Lymphoblastic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612918" ref="tree=MeSH" title="MedGen record for Refractory Acute Lymphoblastic Leukemia">Refractory Acute Lymphoblastic Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1626003" ref="tree=MeSH" title="MedGen record for Refractory B Acute Lymphoblastic Leukemia, BCR-ABL1-Like">Refractory B Acute Lymphoblastic Leukemia, BCR-ABL1-Like</a></span></li><li><span class="TLline"><a href="/medgen/1655206" ref="tree=MeSH" title="MedGen record for Refractory T Acute Lymphoblastic Leukemia">Refractory T Acute Lymphoblastic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/368378" ref="tree=MeSH" title="MedGen record for T-cell acute lymphoblastic leukemia">T-cell acute lymphoblastic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1385175" ref="tree=MeSH" title="MedGen record for Early T cell progenitor acute lymphoblastic leukemia">Early T cell progenitor acute lymphoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/313961" ref="tree=MeSH" title="MedGen record for Mediastinal T Acute Lymphoblastic Leukemia">Mediastinal T Acute Lymphoblastic Leukemia</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/44124" ref="tree=MeSH" title="MedGen record for Acute megakaryoblastic leukemia">Acute megakaryoblastic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/79016" ref="tree=MeSH" title="MedGen record for Acute megakaryoblastic leukemia in adult">Acute megakaryoblastic leukemia in adult</a></span></li><li><span class="TLline"><a href="/medgen/1863778" ref="tree=MeSH" title="MedGen record for Acute megakaryoblastic leukemia in down syndrome">Acute megakaryoblastic leukemia in down syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1843134" ref="tree=MeSH" title="MedGen record for Acute megakaryoblastic leukemia without down syndrome">Acute megakaryoblastic leukemia without down syndrome</a></span></li><li><span class="TLline"><a href="/medgen/79023" ref="tree=MeSH" title="MedGen record for Childhood acute megakaryoblastic leukemia">Childhood acute megakaryoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1718677" ref="tree=MeSH" title="MedGen record for Recurrent Acute Megakaryoblastic Leukemia">Recurrent Acute Megakaryoblastic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7319" ref="tree=MeSH" title="MedGen record for Acute monocytic leukemia">Acute monocytic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/9730" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia">Acute myeloid leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/7314" ref="tree=MeSH" title="MedGen record for Acute basophilic leukemia">Acute basophilic leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/124637" ref="tree=MeSH" title="MedGen record for Adult Acute Basophilic Leukemia">Adult Acute Basophilic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/83536" ref="tree=MeSH" title="MedGen record for Childhood Acute Basophilic Leukemia">Childhood Acute Basophilic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/44121" ref="tree=MeSH" title="MedGen record for Acute Eosinophilic Leukemia">Acute Eosinophilic Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/76005" ref="tree=MeSH" title="MedGen record for Adult Acute Eosinophilic Leukemia">Adult Acute Eosinophilic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/79022" ref="tree=MeSH" title="MedGen record for Childhood Acute Eosinophilic Leukemia">Childhood Acute Eosinophilic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/824521" ref="tree=MeSH" title="MedGen record for Acute Monoblastic and Monocytic Leukemia">Acute Monoblastic and Monocytic Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/141597" ref="tree=MeSH" title="MedGen record for Acute monoblastic leukemia">Acute monoblastic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/272289" ref="tree=MeSH" title="MedGen record for Adult Acute Monoblastic and Monocytic Leukemia">Adult Acute Monoblastic and Monocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/272456" ref="tree=MeSH" title="MedGen record for Childhood Acute Monoblastic and Monocytic Leukemia">Childhood Acute Monoblastic and Monocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1719565" ref="tree=MeSH" title="MedGen record for Recurrent Acute Monoblastic and Monocytic Leukemia">Recurrent Acute Monoblastic and Monocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1734713" ref="tree=MeSH" title="MedGen record for Refractory Acute Monoblastic and Monocytic Leukemia">Refractory Acute Monoblastic and Monocytic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/361829" ref="tree=MeSH" title="MedGen record for Acute myeloblastic leukemia with maturation">Acute myeloblastic leukemia with maturation</a></span><ul><li><span class="TLline"><a href="/medgen/83534" ref="tree=MeSH" title="MedGen record for Adult Acute Myeloid Leukemia with Maturation">Adult Acute Myeloid Leukemia with Maturation</a></span></li><li><span class="TLline"><a href="/medgen/124638" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia with Maturation">Childhood Acute Myeloid Leukemia with Maturation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/10232" ref="tree=MeSH" title="MedGen record for Acute myeloblastic leukemia without maturation">Acute myeloblastic leukemia without maturation</a></span><ul><li><span class="TLline"><a href="/medgen/83533" ref="tree=MeSH" title="MedGen record for Adult Acute Myeloid Leukemia without Maturation">Adult Acute Myeloid Leukemia without Maturation</a></span></li><li><span class="TLline"><a href="/medgen/79018" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia without Maturation">Childhood Acute Myeloid Leukemia without Maturation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/101100" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with minimal differentiation">Acute myeloid leukemia with minimal differentiation</a></span><ul><li><span class="TLline"><a href="/medgen/76319" ref="tree=MeSH" title="MedGen record for Adult Acute Myeloid Leukemia with Minimal Differentiation">Adult Acute Myeloid Leukemia with Minimal Differentiation</a></span></li><li><span class="TLline"><a href="/medgen/129065" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia with Minimal Differentiation">Childhood Acute Myeloid Leukemia with Minimal Differentiation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/224861" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with multilineage dysplasia">Acute myeloid leukemia with multilineage dysplasia</a></span><ul><li><span class="TLline"><a href="/medgen/1649394" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myeloid Leukemia with Multilineage Dysplasia">Recurrent Acute Myeloid Leukemia with Multilineage Dysplasia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/220899" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with recurrent genetic anomaly">Acute myeloid leukemia with recurrent genetic anomaly</a></span><ul><li><span class="TLline"><a href="/medgen/414840" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1">Acute Myeloid Leukemia (Megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1</a></span></li><li><span class="TLline"><a href="/medgen/266234" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with 11q23 abnormalities">Acute myeloid leukemia with 11q23 abnormalities</a></span></li><li><span class="TLline"><a href="/medgen/442905" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia with a Variant RARA Rearrangement">Acute Myeloid Leukemia with a Variant RARA Rearrangement</a></span></li><li><span class="TLline"><a href="/medgen/1716406" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)">Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)</a></span></li><li><span class="TLline"><a href="/medgen/1377153" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with BCR-ABL1">Acute myeloid leukemia with BCR-ABL1</a></span></li><li><span class="TLline"><a href="/medgen/1640289" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with CEBPA somatic mutations">Acute myeloid leukemia with CEBPA somatic mutations</a></span></li><li><span class="TLline"><a href="/medgen/414839" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with DEK::NUP214 fusion">Acute myeloid leukemia with DEK::NUP214 fusion</a></span></li><li><span class="TLline"><a href="/medgen/415269" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)">Acute myeloid leukemia with inv3(p21;q26.2) or t(3;3)(p21;q26.2)</a></span></li><li><span class="TLline"><a href="/medgen/1376688" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with t(8;16)(p11;p13) translocation">Acute myeloid leukemia with t(8;16)(p11;p13) translocation</a></span></li><li><span class="TLline"><a href="/medgen/224862" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia with t(8;21)(q22;q22) translocation">Acute myeloid leukemia with t(8;21)(q22;q22) translocation</a></span></li><li><span class="TLline"><a href="/medgen/1696774" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia with Trisomy 8">Acute Myeloid Leukemia with Trisomy 8</a></span></li><li><span class="TLline"><a href="/medgen/44127" ref="tree=MeSH" title="MedGen record for Acute promyelocytic leukemia">Acute promyelocytic leukemia</a></span></li><li><span class="TLline"><a href="/medgen/389485" ref="tree=MeSH" title="MedGen record for Adult Acute Myeloid Leukemia with Recurrent Genetic Abnormalities">Adult Acute Myeloid Leukemia with Recurrent Genetic Abnormalities</a></span></li><li><span class="TLline"><a href="/medgen/825586" ref="tree=MeSH" title="MedGen record for Core binding factor acute myeloid leukemia">Core binding factor acute myeloid leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1638466" ref="tree=MeSH" title="MedGen record for Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)">Megakaryoblastic acute myeloid leukemia with t(1;22)(p13;q13)</a></span></li><li><span class="TLline"><a href="/medgen/1665215" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities">Recurrent Acute Myeloid Leukemia with Recurrent Genetic Abnormalities</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7316" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia, M6 type">Acute myeloid leukemia, M6 type</a></span><ul><li><span class="TLline"><a href="/medgen/79015" ref="tree=MeSH" title="MedGen record for Adult Acute Erythroid Leukemia">Adult Acute Erythroid Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/232341" ref="tree=MeSH" title="MedGen record for Childhood Acute Erythroid Leukemia">Childhood Acute Erythroid Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1614281" ref="tree=MeSH" title="MedGen record for Erythroleukemia">Erythroleukemia</a></span></li><li><span class="TLline"><a href="/medgen/1790819" ref="tree=MeSH" title="MedGen record for Erythroleukemia, familial, susceptibility to">Erythroleukemia, familial, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/1626382" ref="tree=MeSH" title="MedGen record for Pure Erythroid Leukemia">Pure Erythroid Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1669222" ref="tree=MeSH" title="MedGen record for Recurrent Acute Erythroid Leukemia">Recurrent Acute Erythroid Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/414578" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia, Myelodysplasia-Related">Acute Myeloid Leukemia, Myelodysplasia-Related</a></span><ul><li><span class="TLline"><a href="/medgen/231352" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome">Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome</a></span></li><li><span class="TLline"><a href="/medgen/902081" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related">Recurrent Acute Myeloid Leukemia, Myelodysplasia-Related</a></span></li><li><span class="TLline"><a href="/medgen/1793142" ref="tree=MeSH" title="MedGen record for Refractory Acute Myeloid Leukemia, Myelodysplasia-Related">Refractory Acute Myeloid Leukemia, Myelodysplasia-Related</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/9732" ref="tree=MeSH" title="MedGen record for Acute myelomonocytic leukemia M4">Acute myelomonocytic leukemia M4</a></span><ul><li><span class="TLline"><a href="/medgen/272281" ref="tree=MeSH" title="MedGen record for Acute Myelomonocytic Leukemia with Abnormal Eosinophils">Acute Myelomonocytic Leukemia with Abnormal Eosinophils</a></span></li><li><span class="TLline"><a href="/medgen/310448" ref="tree=MeSH" title="MedGen record for Acute Myelomonocytic Leukemia without Abnormal Eosinophils">Acute Myelomonocytic Leukemia without Abnormal Eosinophils</a></span></li><li><span class="TLline"><a href="/medgen/76003" ref="tree=MeSH" title="MedGen record for Adult Acute Myelomonocytic Leukemia">Adult Acute Myelomonocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/124639" ref="tree=MeSH" title="MedGen record for Childhood Acute Myelomonocytic Leukemia">Childhood Acute Myelomonocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1712090" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myelomonocytic Leukemia">Recurrent Acute Myelomonocytic Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1758507" ref="tree=MeSH" title="MedGen record for Refractory Acute Myelomonocytic Leukemia">Refractory Acute Myelomonocytic Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87279" ref="tree=MeSH" title="MedGen record for Acute panmyelosis with myelofibrosis">Acute panmyelosis with myelofibrosis</a></span></li><li><span class="TLline"><a href="/medgen/113092" ref="tree=MeSH" title="MedGen record for Adult Acute Myeloid Leukemia">Adult Acute Myeloid Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/82982" ref="tree=MeSH" title="MedGen record for Recurrent Adult Acute Myeloid Leukemia">Recurrent Adult Acute Myeloid Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/65075" ref="tree=MeSH" title="MedGen record for Childhood acute myeloid leukemia">Childhood acute myeloid leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1389170" ref="tree=MeSH" title="MedGen record for Acute Megakaryoblastic Leukemia with CBFA2T3-GLIS2">Acute Megakaryoblastic Leukemia with CBFA2T3-GLIS2</a></span></li><li><span class="TLline"><a href="/medgen/1714533" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia with RAM Immunophenotype">Acute Myeloid Leukemia with RAM Immunophenotype</a></span></li><li><span class="TLline"><a href="/medgen/1385022" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia with t(6;11)(q27;q23.3); MLLT4-KMT2A">Acute Myeloid Leukemia with t(6;11)(q27;q23.3); MLLT4-KMT2A</a></span></li><li><span class="TLline"><a href="/medgen/888328" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia with t(7;12)(q36;p13); HLXB9-ETV6">Acute Myeloid Leukemia with t(7;12)(q36;p13); HLXB9-ETV6</a></span></li><li><span class="TLline"><a href="/medgen/889446" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia Not Otherwise Specified">Childhood Acute Myeloid Leukemia Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/881978" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia with Abnormalities of Chromosome 7">Childhood Acute Myeloid Leukemia with Abnormalities of Chromosome 7</a></span></li><li><span class="TLline"><a href="/medgen/888150" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia with Abnormalities of Chromosome 5q">Childhood Acute Myeloid Leukemia with Abnormalities of Chromosome 5q</a></span></li><li><span class="TLline"><a href="/medgen/884951" ref="tree=MeSH" title="MedGen record for Childhood Acute Myeloid Leukemia with NUP98 Rearrangement">Childhood Acute Myeloid Leukemia with NUP98 Rearrangement</a></span></li><li><span class="TLline"><a href="/medgen/79020" ref="tree=MeSH" title="MedGen record for Childhood Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA">Childhood Acute Promyelocytic Leukemia with t(15;17)(q24.1;q21.2); PML-RARA</a></span></li><li><span class="TLline"><a href="/medgen/82981" ref="tree=MeSH" title="MedGen record for Recurrent Childhood Acute Myeloid Leukemia">Recurrent Childhood Acute Myeloid Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/825713" ref="tree=MeSH" title="MedGen record for Cytogenetically Normal Acute Myeloid Leukemia">Cytogenetically Normal Acute Myeloid Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1634915" ref="tree=MeSH" title="MedGen record for Inherited acute myeloid leukemia">Inherited acute myeloid leukemia</a></span></li><li><span class="TLline"><a href="/medgen/44123" ref="tree=MeSH" title="MedGen record for Mast cell leukemia">Mast cell leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1843106" ref="tree=MeSH" title="MedGen record for Acute mast cell leukemia">Acute mast cell leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1843226" ref="tree=MeSH" title="MedGen record for Chronic mast cell leukemia">Chronic mast cell leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1661148" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myeloid Leukemia">Recurrent Acute Myeloid Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1656787" ref="tree=MeSH" title="MedGen record for Recurrent Acute Myeloid Leukemia Not Otherwise Specified">Recurrent Acute Myeloid Leukemia Not Otherwise Specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1627534" ref="tree=MeSH" title="MedGen record for Refractory Acute Myeloid Leukemia">Refractory Acute Myeloid Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1773485" ref="tree=MeSH" title="MedGen record for Refractory Acute Myeloid Leukemia Not Otherwise Specified">Refractory Acute Myeloid Leukemia Not Otherwise Specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/76113" ref="tree=MeSH" title="MedGen record for Secondary Acute Myeloid Leukemia">Secondary Acute Myeloid Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/1760542" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia Arising from Previous Myelodysplastic/Myeloproliferative Neoplasm">Acute Myeloid Leukemia Arising from Previous Myelodysplastic/Myeloproliferative Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/1766651" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia Arising from Previous Myeloproliferative Neoplasm">Acute Myeloid Leukemia Arising from Previous Myeloproliferative Neoplasm</a></span></li><li><span class="TLline"><a href="/medgen/237008" ref="tree=MeSH" title="MedGen record for Acute Myeloid Leukemia Post Cytotoxic Therapy">Acute Myeloid Leukemia Post Cytotoxic Therapy</a></span></li><li><span class="TLline"><a href="/medgen/234037" ref="tree=MeSH" title="MedGen record for Benzene-Related Acute Myeloid Leukemia">Benzene-Related Acute Myeloid Leukemia</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1658558" ref="tree=MeSH" title="MedGen record for Burkitt Leukemia">Burkitt Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/75998" ref="tree=MeSH" title="MedGen record for Adult Burkitt Leukemia">Adult Burkitt Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/83525" ref="tree=MeSH" title="MedGen record for Childhood Burkitt Leukemia">Childhood Burkitt Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1670551" ref="tree=MeSH" title="MedGen record for Recurrent Burkitt Leukemia">Recurrent Burkitt Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1650262" ref="tree=MeSH" title="MedGen record for Refractory Burkitt Leukemia">Refractory Burkitt Leukemia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1668204" ref="tree=MeSH" title="MedGen record for Recurrent Acute Leukemia">Recurrent Acute Leukemia</a></span></li><li><span class="TLline"><a href="/medgen/1662593" ref="tree=MeSH" title="MedGen record for Refractory Acute Leukemia">Refractory Acute Leukemia</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_19351"><div><strong>Storage pool disease of platelets</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>19351</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0032197</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare hemorrhagic disorder due to a constitutional platelet anomaly characterized by moderate to severe deficiency in both platelet alpha-granules and dense bodies, resulting in impaired platelet function and decreased aggregation responses. Patients present increased bleeding tendency with symptoms like easy bruising, or menorrhagia.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/19351">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_322656"><div><strong>Li-Fraumeni syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322656</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835398</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Li-Fraumeni syndrome (LFS) is a cancer predisposition syndrome associated with high risks for a broad spectrum of cancers including early-onset cancers. Five cancer types account for the majority of LFS tumors: adrenocortical carcinomas, breast cancer, central nervous system tumors, osteosarcomas, and soft-tissue sarcomas. Other cancers associated with LFS include leukemia, colorectal cancer, stomach cancer, lung cancer, melanoma, pediatric head and neck cancers, pancreatic cancer, and prostate cancer. Cancer survivors are at increased risk for developing additional primary cancers and treatment-related secondary cancers. The lifetime risks of cancer for women and men with classic LFS are 90% and 70%, respectively, and 50% of cancers occur prior to age 40 years.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/322656">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_502257"><div><strong>Leukemia, acute, X-linked</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>502257</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3501854</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">X-linked form of acute leukemia</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/502257">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_502257" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leukemia, acute, X-linked</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_322656" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Li-Fraumeni syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_19351" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Storage pool disease of platelets</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37156478">Acute Myeloid Leukemia, Version 3.2023, NCCN Clinical Practice Guidelines in Oncology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pollyea DA,
|
||
Altman JK,
|
||
Assi R,
|
||
Bixby D,
|
||
Fathi AT,
|
||
Foran JM,
|
||
Gojo I,
|
||
Hall AC,
|
||
Jonas BA,
|
||
Kishtagari A,
|
||
Lancet J,
|
||
Maness L,
|
||
Mangan J,
|
||
Mannis G,
|
||
Marcucci G,
|
||
Mims A,
|
||
Moriarty K,
|
||
Mustafa Ali M,
|
||
Neff J,
|
||
Nejati R,
|
||
Olin R,
|
||
Percival ME,
|
||
Perl A,
|
||
Przespolewski A,
|
||
Rao D,
|
||
Ravandi F,
|
||
Shallis R,
|
||
Shami PJ,
|
||
Stein E,
|
||
Stone RM,
|
||
Sweet K,
|
||
Thota S,
|
||
Uy G,
|
||
Vachhani P,
|
||
Cassara CJ,
|
||
Freedman-Cass DA,
|
||
Stehman K</span><br />
|
||
<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
|
||
2023 May;21(5):503-513.
|
||
doi: 10.6004/jnccn.2023.0025.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37156478" target="_blank">37156478</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27967252">Hyperleukocytosis and leukostasis: management of a medical emergency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Giammarco S,
|
||
Chiusolo P,
|
||
Piccirillo N,
|
||
Di Giovanni A,
|
||
Metafuni E,
|
||
Laurenti L,
|
||
Sica S,
|
||
Pagano L</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Hematol</span>
|
||
2017 Feb;10(2):147-154.
|
||
Epub 2016 Dec 26
|
||
doi: 10.1080/17474086.2017.1270754.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27967252" target="_blank">27967252</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7953914">Acute leukemia in adults: recent developments in diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Devine SM,
|
||
Larson RA</span><br />
|
||
<span class="medgenPMjournal">CA Cancer J Clin</span>
|
||
1994 Nov-Dec;44(6):326-52.
|
||
doi: 10.3322/canjclin.44.6.326.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7953914" target="_blank">7953914</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22acute%20leukemia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (917)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39890283">Pulmonary Complications in Hematologic Malignancies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McEvoy C,
|
||
Bjoraj P,
|
||
Lee JS</span><br />
|
||
<span class="medgenPMjournal">Clin Chest Med</span>
|
||
2025 Mar;46(1):115-127.
|
||
Epub 2024 Dec 19
|
||
doi: 10.1016/j.ccm.2024.10.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39890283" target="_blank">39890283</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37686807">Early Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kintossou AK,
|
||
Blanco-Lopez J,
|
||
Iguacel I,
|
||
Pisanu S,
|
||
Almeida CCB,
|
||
Steliarova-Foucher E,
|
||
Sierens C,
|
||
Gunter MJ,
|
||
Ladas EJ,
|
||
Barr RD,
|
||
Van Herck K,
|
||
Kozlakidis Z,
|
||
Huybrechts I</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2023 Aug 29;15(17)
|
||
doi: 10.3390/nu15173775.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37686807" target="_blank">37686807</a><a href="/pmc/articles/PMC10489830" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33544265">Mixed Phenotype Acute Leukemia: Current Approaches to Diagnosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alexander TB,
|
||
Orgel E</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol Rep</span>
|
||
2021 Feb 5;23(2):22.
|
||
doi: 10.1007/s11912-020-01010-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33544265" target="_blank">33544265</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21204710">Multiparameter flow cytometry in the diagnosis and management of acute leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peters JM,
|
||
Ansari MQ</span><br />
|
||
<span class="medgenPMjournal">Arch Pathol Lab Med</span>
|
||
2011 Jan;135(1):44-54.
|
||
doi: 10.5858/2010-0387-RAR.1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21204710" target="_blank">21204710</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1434828">Epidemiology and etiology of acute leukemia: an update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sandler DP</span><br />
|
||
<span class="medgenPMjournal">Leukemia</span>
|
||
1992 Nov;6 Suppl 4:3-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1434828" target="_blank">1434828</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20leukemia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5303)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38391169">Myeloma mimicking acute leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mabrouk M,
|
||
Baseggio L</span><br />
|
||
<span class="medgenPMjournal">Ann Biol Clin (Paris)</span>
|
||
2024 Feb 24;81(6):649-650.
|
||
doi: 10.1684/abc.2023.1856.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38391169" target="_blank">38391169</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35775438">How I Diagnose Acute Leukemia of Ambiguous Lineage.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weinberg OK,
|
||
Arber DA</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Pathol</span>
|
||
2022 Jul 1;158(1):27-34.
|
||
doi: 10.1093/ajcp/aqac070.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35775438" target="_blank">35775438</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33544265">Mixed Phenotype Acute Leukemia: Current Approaches to Diagnosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alexander TB,
|
||
Orgel E</span><br />
|
||
<span class="medgenPMjournal">Curr Oncol Rep</span>
|
||
2021 Feb 5;23(2):22.
|
||
doi: 10.1007/s11912-020-01010-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33544265" target="_blank">33544265</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29078921">Acute Leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rose-Inman H,
|
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<div class="nl"><a target="_blank" href="/pubmed/21204710">Multiparameter flow cytometry in the diagnosis and management of acute leukemia.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20leukemia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5385)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/37010259">Ferroptosis in acute leukemia.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lyu T,
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Li X,
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<div class="nl"><a target="_blank" href="/pubmed/33860520">Management of Disseminated Intravascular Coagulation in Acute Leukemias.</a></div>
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<span class="bold">PMID: </span><a href="/pubmed/33860520" target="_blank">33860520</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25696839">Established and novel agents for myelodysplastic syndromes.</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20leukemia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3207)</a></div></div>
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</div>
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<div class="portlet mgSection" id="ID_104">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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<div class="nl"><a target="_blank" href="/pubmed/37686807">Early Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kintossou AK,
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Blanco-Lopez J,
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Iguacel I,
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Pisanu S,
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Almeida CCB,
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Steliarova-Foucher E,
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Sierens C,
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Gunter MJ,
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Ladas EJ,
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Barr RD,
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Van Herck K,
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Kozlakidis Z,
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Huybrechts I</span><br />
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<span class="medgenPMjournal">Nutrients</span>
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2023 Aug 29;15(17)
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<span class="bold">PMID: </span><a href="/pubmed/37686807" target="_blank">37686807</a><a href="/pmc/articles/PMC10489830" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/34058766">Altered Fibrinolysis in Hematological Malignances.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bønløkke ST,
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Ommen HB,
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Hvas AM</span><br />
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<span class="medgenPMjournal">Semin Thromb Hemost</span>
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2021 Jul;47(5):569-580.
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Epub 2021 May 31
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<span class="bold">PMID: </span><a href="/pubmed/34058766" target="_blank">34058766</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30921533">Treatment of venous thromboembolism in acute leukemia: A systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Ahrari A,
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Al-Ani F,
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Wang YP,
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Lazo-Langner A</span><br />
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<span class="medgenPMjournal">Thromb Res</span>
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2019 Jun;178:1-6.
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<span class="bold">PMID: </span><a href="/pubmed/30921533" target="_blank">30921533</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/25269391">Prophylaxis for Pneumocystis pneumonia (PCP) in non-HIV immunocompromised patients.</a></div>
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||
<div class="portlet_content ln"><span class="medgenPMauthor">Stern A,
|
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Green H,
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Paul M,
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Vidal L,
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Leibovici L</span><br />
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<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
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2014 Oct 1;2014(10):CD005590.
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doi: 10.1002/14651858.CD005590.pub3.
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<span class="bold">PMID: </span><a href="/pubmed/25269391" target="_blank">25269391</a><a href="/pmc/articles/PMC6457644" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16483649">Cholecystitis in neutropenic patients: retrospective study and systematic review.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gorschlüter M,
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Mey U,
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Strehl J,
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Schepke M,
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Lamberti C,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Acute%20leukemia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (61)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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||
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||
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||
|
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||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0085669%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (8)</a></li>
|
||
<li><a href="/gtr/tests?term=C0085669%5bDISCUI%5d&filter=method%3A3%5F23" target="_blank">FISH-interphase (2)</a></li>
|
||
<li><a href="/gtr/tests?term=C0085669%5bDISCUI%5d&filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0085669%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (8)</a></li>
|
||
<li><a href="/gtr/tests?term=C0085669%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0085669%5bDISCUI%5d" target="_blank">See all (13)</a></total></li>
|
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Acute%20leukemia" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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