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<meta name="keywords" content="C0919267, neoplasm of ovary, neoplasm of the ovaries, neoplasm of the ovary, neoplasm, ovarian, neoplasm, ovary, neoplasms, ovarian, neoplasms, ovary, neoplastic process, ovarian cancer, ovarian neoplasia, ovarian neoplasm, ovarian neoplasms, ovarian tumor, ovarian tumors, ovarian tumour, ovarian tumours, ovary neoplasm, ovary neoplasm (disease), ovary neoplasms, ovary tumor, ovary tumour, tumor of ovary, tumor of the ovary, tumour of ovary, tumour of the ovary, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A tumor (abnormal growth of tissue) of the ovary." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Ovarian neoplasm (Concept Id: C0919267)
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<!--
UID=181539
ConceptID=C0919267
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Ovarian neoplasm</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>181539</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0919267</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Neoplasm of ovary; Ovarian Neoplasms; Ovarian tumor</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Ovarian tumor (123843001); Tumor of ovary (123843001); Neoplasm of ovary (123843001)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help" data-jig="ncbipopper" href="#target-gene-related">Related genes:<img src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div id="target-gene-related" class="display-none">
Gene(s) associated with related conditions. For conditions<br />
in a hierarchy, the parent condition will list the genes<br />
associated with the children conditions.</div></td>
<td><a target="_blank" href="/gene/5290">PIK3CA</a>, <a target="_blank" href="/gene/5071">PRKN</a>, <a target="_blank" href="/gene/4978">OPCML</a>, <a target="_blank" href="/gene/2064">ERBB2</a>, <a target="_blank" href="/gene/1499">CTNNB1</a>, <a target="_blank" href="/gene/999">CDH1</a>, <a target="_blank" href="/gene/207">AKT1</a></td></tr><tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100615">HP:0100615</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0021068" target="_blank">MONDO:0021068</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A tumor (abnormal growth of tissue) of the ovary. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042065[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=22583">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/22583" ref="tree=GTR&amp;ncbi_uid=22583&amp;link_uid=22583" title="View MedGen record for 'Neoplasm of the genitourinary tract'">Neoplasm of the genitourinary tract</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0474809[DISCUI]&amp;test_type=Clinical&amp;redirect=true" ref="ncbi_uid=105374">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/105374" ref="tree=GTR&amp;ncbi_uid=105374&amp;link_uid=105374" title="View MedGen record for 'Endometrioid tumor'">Endometrioid tumor</a></span></li><li class="TLclosed"><span class="TLline"><a href="/medgen/69146" ref="tree=GTR&amp;ncbi_uid=69146&amp;link_uid=69146" title="View MedGen record for 'Kidney angiomyolipoma'">Kidney angiomyolipoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0376358[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=138169">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=138169" target="_blank" href="/omim/176807">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=138169" ref="ncbi_uid=138169">V</a></span></span><span class="TLline"><a href="/medgen/138169" ref="tree=GTR&amp;ncbi_uid=138169&amp;link_uid=138169" title="View MedGen record for 'Malignant tumor of prostate'">Malignant tumor of prostate</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2931456[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=419810">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=419810" ref="ncbi_uid=419810">V</a></span></span><span class="TLline"><a href="/medgen/419810" ref="tree=GTR&amp;ncbi_uid=419810&amp;link_uid=419810" title="View MedGen record for 'Familial prostate cancer'">Familial prostate cancer</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0153594[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=56313">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=56313" ref="ncbi_uid=56313">V</a></span></span><span class="TLline"><a href="/medgen/56313" ref="tree=GTR&amp;ncbi_uid=56313&amp;link_uid=56313" title="View MedGen record for 'Malignant tumor of testis'">Malignant tumor of testis</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336708[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=277809">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=277809" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=277809" ref="ncbi_uid=277809">V</a></span></span><span class="TLline"><a href="/medgen/277809" ref="tree=GTR&amp;ncbi_uid=277809&amp;link_uid=277809" title="View MedGen record for 'Germ cell tumor of testis'">Germ cell tumor of testis</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=11371" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/11371" ref="tree=GTR&amp;ncbi_uid=11371&amp;link_uid=11371" title="View MedGen record for 'Seminoma'">Seminoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=68669" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/68669" ref="tree=GTR&amp;ncbi_uid=68669&amp;link_uid=68669" title="View MedGen record for 'Testicular teratoma'">Testicular teratoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=102281" target="_blank" href="/omim/191600">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/102281" ref="tree=GTR&amp;ncbi_uid=102281&amp;link_uid=102281" title="View MedGen record for 'Malignant tumor of ureter'">Malignant tumor of ureter</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0005684[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=14150">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=14150" target="_blank" href="/omim/109800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=14150" ref="ncbi_uid=14150">V</a></span></span><span class="TLline"><a href="/medgen/14150" ref="tree=GTR&amp;ncbi_uid=14150&amp;link_uid=14150" title="View MedGen record for 'Malignant tumor of urinary bladder'">Malignant tumor of urinary bladder</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0699885[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=147071">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/147071" ref="tree=GTR&amp;ncbi_uid=147071&amp;link_uid=147071" title="View MedGen record for 'Urinary bladder carcinoma'">Urinary bladder carcinoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0015558[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=8775">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8775" ref="tree=GTR&amp;ncbi_uid=8775&amp;link_uid=8775" title="View MedGen record for 'Neoplasm of fallopian tube'">Neoplasm of fallopian tube</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042138[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=12030">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=12030" ref="ncbi_uid=12030">V</a></span></span><span class="TLline"><a href="/medgen/12030" ref="tree=GTR&amp;ncbi_uid=12030&amp;link_uid=12030" title="View MedGen record for 'Neoplasm of uterus'">Neoplasm of uterus</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0014170[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=8619">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8619" ref="tree=GTR&amp;ncbi_uid=8619&amp;link_uid=8619" title="View MedGen record for 'Endometrium neoplasm'">Endometrium neoplasm</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0007873[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=40201">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/40201" ref="tree=GTR&amp;ncbi_uid=40201&amp;link_uid=40201" title="View MedGen record for 'Neoplasm of uterine cervix'">Neoplasm of uterine cervix</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/91094" ref="tree=GTR&amp;ncbi_uid=91094&amp;link_uid=91094" title="View MedGen record for 'Oncocytoma of kidney'">Oncocytoma of kidney</a></span></li><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0919267[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=181539">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=181539" ref="ncbi_uid=181539">V</a></span></span><span class="TLline">Ovarian neoplasm</span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1333992[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=272713">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=272713" ref="ncbi_uid=272713">V</a></span></span><span class="TLline"><a href="/medgen/272713" ref="tree=GTR&amp;ncbi_uid=272713&amp;link_uid=272713" title="View MedGen record for 'Familial ovarian carcinoma'">Familial ovarian carcinoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1140680[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=216027">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=216027" target="_blank" href="/omim/167000">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=216027" ref="ncbi_uid=216027">V</a></span></span><span class="TLline"><a href="/medgen/216027" ref="tree=GTR&amp;ncbi_uid=216027&amp;link_uid=216027" title="View MedGen record for 'Ovarian cancer'">Ovarian cancer</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1868358[DISCUI]&amp;test_type=Clinical&amp;redirect=true" ref="ncbi_uid=358303">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=358303" target="_blank" href="/omim/171834">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=358303" ref="ncbi_uid=358303">V</a></span></span><span class="TLline"><a href="/medgen/358303" ref="tree=GTR&amp;ncbi_uid=358303&amp;link_uid=358303" title="View MedGen record for 'OVARIAN CANCER, EPITHELIAL, SOMATIC'">OVARIAN CANCER, EPITHELIAL, SOMATIC</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336839[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=237026">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=237026" target="_blank" href="/omim/164860">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=237026" ref="ncbi_uid=237026">V</a></span></span><span class="TLline"><a href="/medgen/237026" ref="tree=GTR&amp;ncbi_uid=237026&amp;link_uid=237026" title="View MedGen record for 'Papillary renal cell carcinoma type 1'">Papillary renal cell carcinoma type 1</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1266142[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=690113">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/690113" ref="tree=GTR&amp;ncbi_uid=690113&amp;link_uid=690113" title="View MedGen record for 'Renal hamartoma'">Renal hamartoma</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/508335" ref="tree=MeSH" title="MedGen record for Disorder of the genitourinary system">Disorder of the genitourinary system</a></span><ul><li><span class="TLline"><a href="/medgen/1783801" ref="tree=MeSH" title="MedGen record for Diseases, Genital">Diseases, Genital</a></span><ul><li><span class="TLline"><a href="/medgen/9003" ref="tree=MeSH" title="MedGen record for Disorder of female genital system">Disorder of female genital system</a></span><ul><li><span class="TLline"><a href="/medgen/1763" ref="tree=MeSH" title="MedGen record for Adnexal Diseases">Adnexal Diseases</a></span><ul><li><span class="TLline"><a href="/medgen/45256" ref="tree=MeSH" title="MedGen record for Disorder of ovary">Disorder of ovary</a></span><ul><li><span class="matched_ds">Ovarian neoplasm</span><ul><li><span class="TLline"><a href="/medgen/2345" ref="tree=MeSH" title="MedGen record for Brenner Tumor">Brenner Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1716777" ref="tree=MeSH" title="MedGen record for Ovarian Brenner tumor">Ovarian Brenner tumor</a></span><ul><li><span class="TLline"><a href="/medgen/99183" ref="tree=MeSH" title="MedGen record for Benign Ovarian Brenner Tumor">Benign Ovarian Brenner Tumor</a></span></li><li><span class="TLline"><a href="/medgen/90792" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Brenner Tumor">Borderline Ovarian Brenner Tumor</a></span></li><li><span class="TLline"><a href="/medgen/90793" ref="tree=MeSH" title="MedGen record for Malignant ovarian Brenner tumor">Malignant ovarian Brenner tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/273631" ref="tree=MeSH" title="MedGen record for Testicular Brenner tumor">Testicular Brenner tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/61661" ref="tree=MeSH" title="MedGen record for Endometrioid carcinoma">Endometrioid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272713" ref="tree=MeSH" title="MedGen record for Familial ovarian carcinoma">Familial ovarian carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1635506" ref="tree=MeSH" title="MedGen record for BRCA-Associated Ovarian Carcinoma">BRCA-Associated Ovarian Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1637849" ref="tree=MeSH" title="MedGen record for Recurrent BRCA- Associated Ovarian Carcinoma">Recurrent BRCA- Associated Ovarian Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/57706" ref="tree=MeSH" title="MedGen record for Fibroma of ovary">Fibroma of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/277455" ref="tree=MeSH" title="MedGen record for Ovarian Cellular Fibroma">Ovarian Cellular Fibroma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/6676" ref="tree=MeSH" title="MedGen record for Granulosa cell tumor">Granulosa cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/361158" ref="tree=MeSH" title="MedGen record for Adult Granulosa Cell Tumor">Adult Granulosa Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/231362" ref="tree=MeSH" title="MedGen record for Adult Ovarian Granulosa Cell Tumor">Adult Ovarian Granulosa Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/272840" ref="tree=MeSH" title="MedGen record for Adult type testicular granulosa cell tumor">Adult type testicular granulosa cell tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83141" ref="tree=MeSH" title="MedGen record for Juvenile Granulosa Cell Tumor">Juvenile Granulosa Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/340891" ref="tree=MeSH" title="MedGen record for Juvenile type ovarian granulosa cell tumor">Juvenile type ovarian granulosa cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/308257" ref="tree=MeSH" title="MedGen record for Juvenile type testicular granulosa cell tumor">Juvenile type testicular granulosa cell tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87235" ref="tree=MeSH" title="MedGen record for Malignant Granulosa Cell Tumor">Malignant Granulosa Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/138043" ref="tree=MeSH" title="MedGen record for Maligant granulosa cell tumor of ovary">Maligant granulosa cell tumor of ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277970" ref="tree=MeSH" title="MedGen record for Ovarian granulosa cell tumor">Ovarian granulosa cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/237001" ref="tree=MeSH" title="MedGen record for Testicular granulosa cell tumor">Testicular granulosa cell tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/151793" ref="tree=MeSH" title="MedGen record for Hereditary breast ovarian cancer syndrome">Hereditary breast ovarian cancer syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/231922" ref="tree=MeSH" title="MedGen record for BRCA1-Associated Hereditary Breast and Ovarian Cancer Syndrome">BRCA1-Associated Hereditary Breast and Ovarian Cancer Syndrome</a></span></li><li><span class="TLline"><a href="/medgen/231923" ref="tree=MeSH" title="MedGen record for BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome">BRCA2-Associated Hereditary Breast and Ovarian Cancer Syndrome</a></span></li><li><span class="TLline"><a href="/medgen/382914" ref="tree=MeSH" title="MedGen record for Breast-ovarian cancer, familial, susceptibility to, 1">Breast-ovarian cancer, familial, susceptibility to, 1</a></span></li><li><span class="TLline"><a href="/medgen/382625" ref="tree=MeSH" title="MedGen record for Breast-ovarian cancer, familial, susceptibility to, 2">Breast-ovarian cancer, familial, susceptibility to, 2</a></span></li><li><span class="TLline"><a href="/medgen/462009" ref="tree=MeSH" title="MedGen record for Breast-ovarian cancer, familial, susceptibility to, 3">Breast-ovarian cancer, familial, susceptibility to, 3</a></span></li><li><span class="TLline"><a href="/medgen/481975" ref="tree=MeSH" title="MedGen record for Breast-ovarian cancer, familial, susceptibility to, 4">Breast-ovarian cancer, familial, susceptibility to, 4</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/6287" ref="tree=MeSH" title="MedGen record for Meigs syndrome">Meigs syndrome</a></span></li><li><span class="TLline"><a href="/medgen/14058" ref="tree=MeSH" title="MedGen record for Ovarian benign neoplasm">Ovarian benign neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/83411" ref="tree=MeSH" title="MedGen record for Benign Ovarian Epithelial Tumor">Benign Ovarian Epithelial Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/307263" ref="tree=MeSH" title="MedGen record for Benign Ovarian Clear Cell Tumor">Benign Ovarian Clear Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/384480" ref="tree=MeSH" title="MedGen record for Benign Ovarian Endometrioid Tumor">Benign Ovarian Endometrioid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/267038" ref="tree=MeSH" title="MedGen record for Benign ovarian mucinous tumor">Benign ovarian mucinous tumor</a></span></li><li><span class="TLline"><a href="/medgen/272361" ref="tree=MeSH" title="MedGen record for Benign Ovarian Seromucinous Tumor">Benign Ovarian Seromucinous Tumor</a></span></li><li><span class="TLline"><a href="/medgen/272362" ref="tree=MeSH" title="MedGen record for Benign Ovarian Serous Tumor">Benign Ovarian Serous Tumor</a></span></li><li><span class="TLline"><a href="/medgen/138041" ref="tree=MeSH" title="MedGen record for Ovarian cystadenoma">Ovarian cystadenoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/138045" ref="tree=MeSH" title="MedGen record for Benign Ovarian Germ Cell Tumor">Benign Ovarian Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233672" ref="tree=MeSH" title="MedGen record for Mature ovarian teratoma">Mature ovarian teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/231435" ref="tree=MeSH" title="MedGen record for Benign ovarian sex cord-stromal tumor">Benign ovarian sex cord-stromal tumor</a></span><ul><li><span class="TLline"><a href="/medgen/231436" ref="tree=MeSH" title="MedGen record for Benign Ovarian Thecoma">Benign Ovarian Thecoma</a></span></li><li><span class="TLline"><a href="/medgen/889995" ref="tree=MeSH" title="MedGen record for Ovarian microcystic stromal tumor">Ovarian microcystic stromal tumor</a></span></li><li><span class="TLline"><a href="/medgen/235083" ref="tree=MeSH" title="MedGen record for Ovarian Sclerosing Stromal Tumor">Ovarian Sclerosing Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/276673" ref="tree=MeSH" title="MedGen record for Ovarian Stromal-Leydig Cell Tumor">Ovarian Stromal-Leydig Cell Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/926077" ref="tree=MeSH" title="MedGen record for Ovarian Adenomatoid Tumor">Ovarian Adenomatoid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1792083" ref="tree=MeSH" title="MedGen record for Ovarian Leiomyoma">Ovarian Leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/235421" ref="tree=MeSH" title="MedGen record for Ovarian Myxoma">Ovarian Myxoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/216027" ref="tree=MeSH" title="MedGen record for Ovarian cancer">Ovarian cancer</a></span><ul><li><span class="TLline"><a href="/medgen/266966" ref="tree=MeSH" title="MedGen record for Adenocarcinofibroma">Adenocarcinofibroma</a></span><ul><li><span class="TLline"><a href="/medgen/384483" ref="tree=MeSH" title="MedGen record for Ovarian clear cell malignant adenofibroma">Ovarian clear cell malignant adenofibroma</a></span></li><li><span class="TLline"><a href="/medgen/384497" ref="tree=MeSH" title="MedGen record for Ovarian mucinous adenocarcinofibroma">Ovarian mucinous adenocarcinofibroma</a></span></li><li><span class="TLline"><a href="/medgen/473548" ref="tree=MeSH" title="MedGen record for Ovarian Serous Adenocarcinofibroma">Ovarian Serous Adenocarcinofibroma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/91089" ref="tree=MeSH" title="MedGen record for Choriocarcinoma of ovary">Choriocarcinoma of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/274586" ref="tree=MeSH" title="MedGen record for Gestational ovarian choriocarcinoma">Gestational ovarian choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/274798" ref="tree=MeSH" title="MedGen record for Non-gestational ovarian choriocarcinoma">Non-gestational ovarian choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163165" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Choriocarcinoma">Stage I Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/167734" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Choriocarcinoma">Stage II Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163166" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Choriocarcinoma">Stage III Ovarian Choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/167735" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Choriocarcinoma">Stage IV Ovarian Choriocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1737130" ref="tree=MeSH" title="MedGen record for Extrarenal Rhabdoid Tumor of the Ovary">Extrarenal Rhabdoid Tumor of the Ovary</a></span><ul><li><span class="TLline"><a href="/medgen/1734687" ref="tree=MeSH" title="MedGen record for Recurrent Extrarenal Rhabdoid Tumor of the Ovary">Recurrent Extrarenal Rhabdoid Tumor of the Ovary</a></span></li><li><span class="TLline"><a href="/medgen/1749849" ref="tree=MeSH" title="MedGen record for Refractory Extrarenal Rhabdoid Tumor of the Ovary">Refractory Extrarenal Rhabdoid Tumor of the Ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87544" ref="tree=MeSH" title="MedGen record for Malignant germ cell tumor of ovary">Malignant germ cell tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/164003" ref="tree=MeSH" title="MedGen record for Childhood Malignant Ovarian Germ Cell Tumor">Childhood Malignant Ovarian Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/798473" ref="tree=MeSH" title="MedGen record for Malignant dysgerminomatous germ cell tumor of ovary">Malignant dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1826164" ref="tree=MeSH" title="MedGen record for Malignant non-dysgerminomatous germ cell tumor of ovary">Malignant non-dysgerminomatous germ cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/1657209" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Teratoma">Malignant Ovarian Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/137777" ref="tree=MeSH" title="MedGen record for Malignant struma ovarii">Malignant struma ovarii</a></span></li><li><span class="TLline"><a href="/medgen/275291" ref="tree=MeSH" title="MedGen record for Ovarian primitive germ cell tumor">Ovarian primitive germ cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/906353" ref="tree=MeSH" title="MedGen record for Primary non-gestational choriocarcinoma of ovary">Primary non-gestational choriocarcinoma of ovary</a></span></li><li><span class="TLline"><a href="/medgen/79058" ref="tree=MeSH" title="MedGen record for Recurrent Ovarian Germ Cell Tumor">Recurrent Ovarian Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/124681" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Germ Cell Tumor AJCC v6 and v7">Stage I Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/76052" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Germ Cell Tumor AJCC v6 and v7">Stage II Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/124682" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Germ Cell Tumor AJCC v6 and v7">Stage III Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1669130" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7">Stage IV Ovarian Germ Cell Tumor AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/273560" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Epithelial Tumor">Malignant Ovarian Epithelial Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/309396" ref="tree=MeSH" title="MedGen record for Malignant ovarian serous tumor">Malignant ovarian serous tumor</a></span></li><li><span class="TLline"><a href="/medgen/274767" ref="tree=MeSH" title="MedGen record for Mucinous ovarian cancer">Mucinous ovarian cancer</a></span></li><li><span class="TLline"><a href="/medgen/1648335" ref="tree=MeSH" title="MedGen record for Ovarian carcinoma">Ovarian carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/276544" ref="tree=MeSH" title="MedGen record for Ovarian clear cell cancer">Ovarian clear cell cancer</a></span></li><li><span class="TLline"><a href="/medgen/276545" ref="tree=MeSH" title="MedGen record for Ovarian endometrial cancer">Ovarian endometrial cancer</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233667" ref="tree=MeSH" title="MedGen record for Malignant sex cord stromal tumor of ovary">Malignant sex cord stromal tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/412169" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Steroid Cell Tumor">Malignant Ovarian Steroid Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/83139" ref="tree=MeSH" title="MedGen record for Malignant Ovarian Thecoma">Malignant Ovarian Thecoma</a></span></li><li><span class="TLline"><a href="/medgen/1825991" ref="tree=MeSH" title="MedGen record for Malignant Sertoli-Leydig cell tumor of ovary">Malignant Sertoli-Leydig cell tumor of ovary</a></span></li><li><span class="TLline"><a href="/medgen/83412" ref="tree=MeSH" title="MedGen record for Ovarian gynandroblastoma">Ovarian gynandroblastoma</a></span></li><li><span class="TLline"><a href="/medgen/362651" ref="tree=MeSH" title="MedGen record for Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor">Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/904268" ref="tree=MeSH" title="MedGen record for Theca steroid-producing cell malignant tumor of ovary, not further specified">Theca steroid-producing cell malignant tumor of ovary, not further specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/777081" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Neoplasm in the Ovary">Metastatic Malignant Neoplasm in the Ovary</a></span><ul><li><span class="TLline"><a href="/medgen/9652" ref="tree=MeSH" title="MedGen record for Krukenberg carcinoma">Krukenberg carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276669" ref="tree=MeSH" title="MedGen record for Ovarian lymphoma">Ovarian lymphoma</a></span></li><li><span class="TLline"><a href="/medgen/274089" ref="tree=MeSH" title="MedGen record for Ovarian malignant mesothelioma">Ovarian malignant mesothelioma</a></span></li><li><span class="TLline"><a href="/medgen/1790038" ref="tree=MeSH" title="MedGen record for Ovarian melanoma">Ovarian melanoma</a></span></li><li><span class="TLline"><a href="/medgen/1792161" ref="tree=MeSH" title="MedGen record for Ovarian Neuroectodermal-Type Tumor">Ovarian Neuroectodermal-Type Tumor</a></span></li><li><span class="TLline"><a href="/medgen/128881" ref="tree=MeSH" title="MedGen record for Ovarian sarcoma">Ovarian sarcoma</a></span><ul><li><span class="TLline"><a href="/medgen/233808" ref="tree=MeSH" title="MedGen record for Liposarcoma of the ovary">Liposarcoma of the ovary</a></span></li><li><span class="TLline"><a href="/medgen/277458" ref="tree=MeSH" title="MedGen record for Ovarian adenosarcoma">Ovarian adenosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233805" ref="tree=MeSH" title="MedGen record for Ovarian angiosarcoma">Ovarian angiosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/235417" ref="tree=MeSH" title="MedGen record for Ovarian Fibrosarcoma">Ovarian Fibrosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/276498" ref="tree=MeSH" title="MedGen record for Ovarian Low Grade Endometrioid Stromal Sarcoma">Ovarian Low Grade Endometrioid Stromal Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/384493" ref="tree=MeSH" title="MedGen record for Ovarian Undifferentiated Sarcoma">Ovarian Undifferentiated Sarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233275" ref="tree=MeSH" title="MedGen record for Ovary leiomyosarcoma">Ovary leiomyosarcoma</a></span></li><li><span class="TLline"><a href="/medgen/233277" ref="tree=MeSH" title="MedGen record for Ovary rhabdomyosarcoma">Ovary rhabdomyosarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/275296" ref="tree=MeSH" title="MedGen record for Ovarian Wilms tumor">Ovarian Wilms tumor</a></span></li><li><span class="TLline"><a href="/medgen/1709430" ref="tree=MeSH" title="MedGen record for Solid Pseudopapillary Neoplasm of the Ovary">Solid Pseudopapillary Neoplasm of the Ovary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/358303" ref="tree=MeSH" title="MedGen record for OVARIAN CANCER, EPITHELIAL, SOMATIC">OVARIAN CANCER, EPITHELIAL, SOMATIC</a></span></li><li><span class="TLline"><a href="/medgen/90969" ref="tree=MeSH" title="MedGen record for Ovarian epithelial tumor">Ovarian epithelial tumor</a></span><ul><li><span class="TLline"><a href="/medgen/777110" ref="tree=MeSH" title="MedGen record for Borderline epithelial tumor of ovary">Borderline epithelial tumor of ovary</a></span><ul><li><span class="TLline"><a href="/medgen/267394" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Clear Cell Tumor">Borderline Ovarian Clear Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1790837" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Endometrioid Tumor">Borderline Ovarian Endometrioid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1699016" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Mixed Epithelial Tumor/Atypical Proliferative Ovarian Mixed Epithelial Tumor">Borderline Ovarian Mixed Epithelial Tumor/Atypical Proliferative Ovarian Mixed Epithelial Tumor</a></span></li><li><span class="TLline"><a href="/medgen/307298" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Mucinous Tumor">Borderline Ovarian Mucinous Tumor</a></span></li><li><span class="TLline"><a href="/medgen/1792001" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Seromucinous Tumor">Borderline Ovarian Seromucinous Tumor</a></span></li><li><span class="TLline"><a href="/medgen/231957" ref="tree=MeSH" title="MedGen record for Borderline ovarian serous tumor">Borderline ovarian serous tumor</a></span></li><li><span class="TLline"><a href="/medgen/857357" ref="tree=MeSH" title="MedGen record for Recurrent Borderline Ovarian Surface Epithelial-Stromal Tumor">Recurrent Borderline Ovarian Surface Epithelial-Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/458925" ref="tree=MeSH" title="MedGen record for Stage I Borderline Ovarian Surface Epithelial-Stromal Tumor">Stage I Borderline Ovarian Surface Epithelial-Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/458926" ref="tree=MeSH" title="MedGen record for Stage II Borderline Ovarian Surface Epithelial-Stromal Tumor">Stage II Borderline Ovarian Surface Epithelial-Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/458927" ref="tree=MeSH" title="MedGen record for Stage III Borderline Ovarian Surface Epithelial-Stromal Tumor">Stage III Borderline Ovarian Surface Epithelial-Stromal Tumor</a></span></li><li><span class="TLline"><a href="/medgen/458928" ref="tree=MeSH" title="MedGen record for Stage IV Borderline Ovarian Surface Epithelial-Stromal Tumor">Stage IV Borderline Ovarian Surface Epithelial-Stromal Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/138040" ref="tree=MeSH" title="MedGen record for Ovarian clear cell tumor">Ovarian clear cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/233273" ref="tree=MeSH" title="MedGen record for Ovarian Endometrioid Tumor">Ovarian Endometrioid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/235419" ref="tree=MeSH" title="MedGen record for Ovarian mucinous tumor">Ovarian mucinous tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1707329" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Mucinous Tumor/Atypical Proliferative Ovarian Mucinous Tumor with Microinvasion">Borderline Ovarian Mucinous Tumor/Atypical Proliferative Ovarian Mucinous Tumor with Microinvasion</a></span></li><li><span class="TLline"><a href="/medgen/309512" ref="tree=MeSH" title="MedGen record for Ovarian Mucinous Cystic Tumor Associated with Pseudomyxoma Peritonei">Ovarian Mucinous Cystic Tumor Associated with Pseudomyxoma Peritonei</a></span></li><li><span class="TLline"><a href="/medgen/269341" ref="tree=MeSH" title="MedGen record for Ovarian Mucinous Cystic Tumor with Mural Nodules">Ovarian Mucinous Cystic Tumor with Mural Nodules</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/99195" ref="tree=MeSH" title="MedGen record for Ovarian papillary tumor">Ovarian papillary tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233276" ref="tree=MeSH" title="MedGen record for Ovarian papillary cystadenoma">Ovarian papillary cystadenoma</a></span></li><li><span class="TLline"><a href="/medgen/233279" ref="tree=MeSH" title="MedGen record for Ovarian serous surface papillary adenocarcinoma">Ovarian serous surface papillary adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235423" ref="tree=MeSH" title="MedGen record for Ovarian surface papilloma">Ovarian surface papilloma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83409" ref="tree=MeSH" title="MedGen record for Ovarian seromucinous tumor">Ovarian seromucinous tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1651770" ref="tree=MeSH" title="MedGen record for Ovarian seromucinous carcinoma">Ovarian seromucinous carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/141653" ref="tree=MeSH" title="MedGen record for Ovarian serous tumor">Ovarian serous tumor</a></span><ul><li><span class="TLline"><a href="/medgen/267395" ref="tree=MeSH" title="MedGen record for Borderline Ovarian Serous Tumor/Atypical Proliferative Ovarian Serous Tumor with Microinvasion">Borderline Ovarian Serous Tumor/Atypical Proliferative Ovarian Serous Tumor with Microinvasion</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1792201" ref="tree=MeSH" title="MedGen record for Ovarian Wolffian Tumor">Ovarian Wolffian Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/65958" ref="tree=MeSH" title="MedGen record for Ovarian germ cell tumor">Ovarian germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/76072" ref="tree=MeSH" title="MedGen record for Ovarian teratoma">Ovarian teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/272466" ref="tree=MeSH" title="MedGen record for Childhood teratoma of the ovary">Childhood teratoma of the ovary</a></span></li><li><span class="TLline"><a href="/medgen/274086" ref="tree=MeSH" title="MedGen record for Ovarian biphasic or triphasic teratoma">Ovarian biphasic or triphasic teratoma</a></span></li><li><span class="TLline"><a href="/medgen/68637" ref="tree=MeSH" title="MedGen record for Ovarian dermoid cyst">Ovarian dermoid cyst</a></span></li><li><span class="TLline"><a href="/medgen/266265" ref="tree=MeSH" title="MedGen record for Ovarian monodermal teratoma">Ovarian monodermal teratoma</a></span></li><li><span class="TLline"><a href="/medgen/1656269" ref="tree=MeSH" title="MedGen record for Stage I Ovarian Teratoma AJCC v6 and v7">Stage I Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1663837" ref="tree=MeSH" title="MedGen record for Stage II Ovarian Teratoma AJCC v6 and v7">Stage II Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1648756" ref="tree=MeSH" title="MedGen record for Stage III Ovarian Teratoma AJCC v6 and v7">Stage III Ovarian Teratoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1661846" ref="tree=MeSH" title="MedGen record for Stage IV Ovarian Teratoma AJCC v6 and v7">Stage IV Ovarian Teratoma AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/162990" ref="tree=MeSH" title="MedGen record for Pediatric ovarian germ cell tumor">Pediatric ovarian germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/899770" ref="tree=MeSH" title="MedGen record for Childhood Ovarian Nongerminomatous Germ Cell Tumor">Childhood Ovarian Nongerminomatous Germ Cell Tumor</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/309510" ref="tree=MeSH" title="MedGen record for Ovarian gonadoblastoma">Ovarian gonadoblastoma</a></span></li><li><span class="TLline"><a href="/medgen/277457" ref="tree=MeSH" title="MedGen record for Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor">Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/1792162" ref="tree=MeSH" title="MedGen record for Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified">Ovarian Mixed Germ Cell-Sex Cord-Stromal Tumor, Unclassified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/277459" ref="tree=MeSH" title="MedGen record for Ovarian neuroendocrine neoplasm">Ovarian neuroendocrine neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/1771718" ref="tree=MeSH" title="MedGen record for Ovarian Neuroendocrine Carcinoma">Ovarian Neuroendocrine Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233809" ref="tree=MeSH" title="MedGen record for Ovarian large-cell neuroendocrine carcinoma">Ovarian large-cell neuroendocrine carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/309517" ref="tree=MeSH" title="MedGen record for Pulmonary type ovarian small cell carcinoma">Pulmonary type ovarian small cell carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233806" ref="tree=MeSH" title="MedGen record for Ovarian Neuroendocrine Tumor">Ovarian Neuroendocrine Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/276668" ref="tree=MeSH" title="MedGen record for Ovarian Insular Carcinoid Tumor">Ovarian Insular Carcinoid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/275290" ref="tree=MeSH" title="MedGen record for Ovarian Mucinous Carcinoid Tumor">Ovarian Mucinous Carcinoid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/276675" ref="tree=MeSH" title="MedGen record for Ovarian Trabecular Carcinoid Tumor">Ovarian Trabecular Carcinoid Tumor</a></span></li><li><span class="TLline"><a href="/medgen/90799" ref="tree=MeSH" title="MedGen record for Strumal Carcinoid">Strumal Carcinoid</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/870531" ref="tree=MeSH" title="MedGen record for Ovarian papillary adenocarcinoma">Ovarian papillary adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/154644" ref="tree=MeSH" title="MedGen record for Ovarian sex cord-stromal tumor">Ovarian sex cord-stromal tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233274" ref="tree=MeSH" title="MedGen record for Ovarian Granulosa-Stromal Cell Tumor">Ovarian Granulosa-Stromal Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/277816" ref="tree=MeSH" title="MedGen record for Ovarian Tumor of the Thecoma/Fibroma Group">Ovarian Tumor of the Thecoma/Fibroma Group</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/309515" ref="tree=MeSH" title="MedGen record for Ovarian sertoli-stromal cell tumor">Ovarian sertoli-stromal cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/311375" ref="tree=MeSH" title="MedGen record for Ovarian Sertoli Cell Tumor">Ovarian Sertoli Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/2038" ref="tree=MeSH" title="MedGen record for Ovarian Sertoli-Leydig cell tumor">Ovarian Sertoli-Leydig cell tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/276804" ref="tree=MeSH" title="MedGen record for Ovarian Sex Cord Tumor with Annular Tubules">Ovarian Sex Cord Tumor with Annular Tubules</a></span></li><li><span class="TLline"><a href="/medgen/275292" ref="tree=MeSH" title="MedGen record for Ovarian Sex Cord-Stromal Tumor Associated with Peutz-Jeghers Syndrome">Ovarian Sex Cord-Stromal Tumor Associated with Peutz-Jeghers Syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1793867" ref="tree=MeSH" title="MedGen record for Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified">Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/137756" ref="tree=MeSH" title="MedGen record for Ovarian Steroid Cell Tumor">Ovarian Steroid Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/233807" ref="tree=MeSH" title="MedGen record for Ovarian Leydig Cell Tumor, Not Otherwise Specified">Ovarian Leydig Cell Tumor, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/309518" ref="tree=MeSH" title="MedGen record for Ovarian Steroid Cell Tumor, Not Otherwise Specified">Ovarian Steroid Cell Tumor, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/44209" ref="tree=MeSH" title="MedGen record for Ovarian Stromal Luteoma">Ovarian Stromal Luteoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/362863" ref="tree=MeSH" title="MedGen record for Ovarian Stromal Tumor with Minor Sex Cord Elements">Ovarian Stromal Tumor with Minor Sex Cord Elements</a></span></li><li><span class="TLline"><a href="/medgen/364155" ref="tree=MeSH" title="MedGen record for Ovarian thecoma">Ovarian thecoma</a></span><ul><li><span class="TLline"><a href="/medgen/90778" ref="tree=MeSH" title="MedGen record for Ovarian Luteinized Thecoma">Ovarian Luteinized Thecoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/277461" ref="tree=MeSH" title="MedGen record for Ovarian Soft Tissue Neoplasm">Ovarian Soft Tissue Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/926076" ref="tree=MeSH" title="MedGen record for Ovarian endometrioid stromal and related neoplasms">Ovarian endometrioid stromal and related neoplasms</a></span></li><li><span class="TLline"><a href="/medgen/1792082" ref="tree=MeSH" title="MedGen record for Ovarian Smooth Muscle Neoplasm">Ovarian Smooth Muscle Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/1792085" ref="tree=MeSH" title="MedGen record for Ovarian Smooth Muscle Tumor of Uncertain Malignant Potential">Ovarian Smooth Muscle Tumor of Uncertain Malignant Potential</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/61669" ref="tree=MeSH" title="MedGen record for Sertoli-Leydig cell tumor">Sertoli-Leydig cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/9747" ref="tree=MeSH" title="MedGen record for Leydig cell tumor">Leydig cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/83142" ref="tree=MeSH" title="MedGen record for Benign Leydig cell tumor">Benign Leydig cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/83143" ref="tree=MeSH" title="MedGen record for Malignant Leydig cell tumor">Malignant Leydig cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/163584" ref="tree=MeSH" title="MedGen record for Testicular Leydig cell tumor">Testicular Leydig cell tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/11387" ref="tree=MeSH" title="MedGen record for Sertoli cell tumor">Sertoli cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/361204" ref="tree=MeSH" title="MedGen record for Benign sertoli cell tumor">Benign sertoli cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/137755" ref="tree=MeSH" title="MedGen record for Malignant Sertoli cell tumor">Malignant Sertoli cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/91165" ref="tree=MeSH" title="MedGen record for Testicular sertoli cell tumor">Testicular sertoli cell tumor</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/21505" ref="tree=MeSH" title="MedGen record for Thecoma">Thecoma</a></span><ul><li><span class="TLline"><a href="/medgen/308260" ref="tree=MeSH" title="MedGen record for Testicular thecoma">Testicular thecoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_231157"><div><strong>Muir-Torré syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>231157</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1321489</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Lynch syndrome is characterized by an increased risk for colorectal cancer (CRC) and cancers of the endometrium, ovary, stomach, small bowel, urinary tract, biliary tract, brain (usually glioblastoma), skin (sebaceous adenomas, sebaceous carcinomas, and keratoacanthomas), pancreas, and prostate. Cancer risks and age of onset vary depending on the associated gene. Several other cancer types have been reported to occur in individuals with Lynch syndrome (e.g., breast, sarcomas, adrenocortical carcinoma). However, the data are not sufficient to demonstrate that the risk of developing these cancers is increased in individuals with Lynch syndrome.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/231157">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_318886"><div><strong>Lynch syndrome 5</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>318886</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1833477</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Lynch syndrome-5 (LYNCH5), or hereditary nonpolyposis colorectal cancer type 5 (HNPCC5), is a cancer predisposition syndrome characterized by onset of colorectal cancer and/or extracolonic cancers, particularly endometrial cancer, usually in mid-adulthood. The disorder shows autosomal dominant inheritance with incomplete penetrance (summary by Castellsague et al., 2015).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of Lynch syndrome, see 120435.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/318886">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_325005"><div><strong>Lynch syndrome 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>325005</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1838333</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Lynch syndrome-4 (LYNCH4), or hereditary nonpolyposis colorectal cancer type 4 (HNPCC4), is an autosomal dominant disorder characterized primarily by the development of early-onset colorectal cancer. It is associated with the development of a variety of epithelial tumors that include endometrial cancer, stomach cancer, and ovarian cancer (summary by Thompson et al., 2004).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/325005">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_382625"><div><strong>Breast-ovarian cancer, familial, susceptibility to, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382625</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2675520</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div></div>
<div class="spaceAbove">BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for female and male breast cancer, ovarian cancer (including fallopian tube and primary peritoneal cancers), and to a lesser extent other cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals with a BRCA2 pathogenic variant. The risk of developing an associated cancer varies depending on whether HBOC is caused by a BRCA1 or BRCA2 pathogenic variant.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/382625">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_382914"><div><strong>Breast-ovarian cancer, familial, susceptibility to, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382914</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2676676</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div></div>
<div class="spaceAbove">BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC) is characterized by an increased risk for female and male breast cancer, ovarian cancer (including fallopian tube and primary peritoneal cancers), and to a lesser extent other cancers such as prostate cancer, pancreatic cancer, and melanoma primarily in individuals with a BRCA2 pathogenic variant. The risk of developing an associated cancer varies depending on whether HBOC is caused by a BRCA1 or BRCA2 pathogenic variant.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/382914">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_816697"><div><strong>Premature ovarian failure 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816697</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3810367</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Premature ovarian failure (POF), the endpoint of primary ovarian insufficiency, affects approximately 1% of women worldwide. Patients with POF present with at least a 6-month history of amenorrhea and elevated plasma levels of follicle-stimulating hormone (more than 40 mIU per milliliter). The disorder can result from premature depletion of the follicle pool, follicular atresia, follicle growth arrest, or ovarian dysgenesis (see 233300). In approximately 10 to 15% of patients with POF, a genetic cause has been determined (summary by Caburet et al., 2014).&#13; For general phenotypic information and a discussion of genetic heterogeneity of premature ovarian failure, see POF1 (311360).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/816697">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_907624"><div><strong>Thyroid cancer, nonmedullary, 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>907624</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4225293</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Nonmedullary thyroid cancer (NMTC) refers to neoplasms originating from the thyroid follicular cells and represents 80 to 95% of all thyroid cancers. Approximately 5% of NMTC occurs on the background of a familial predisposition. Although papillary thyroid carcinoma (PTC) is usually the most frequent thyroid lesion in NMTC families, multinodular goiter (MNG) and follicular thyroid adenoma also occur (summary by Pereira et al., 2015).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of NMTC, see NMTC1 (188550).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/907624">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1632414"><div><strong>Fanconi anemia, complementation group S</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1632414</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4554406</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Fanconi anemia (FA) is characterized by physical abnormalities, bone marrow failure, and increased risk for malignancy. Physical abnormalities, present in approximately 75% of affected individuals, include one or more of the following: short stature, abnormal skin pigmentation, skeletal malformations of the upper and/or lower limbs, microcephaly, and ophthalmic and genitourinary tract anomalies. Progressive bone marrow failure with pancytopenia typically presents in the first decade, often initially with thrombocytopenia or leukopenia. The incidence of acute myeloid leukemia is 13% by age 50 years. Solid tumors particularly of the head and neck, skin, and genitourinary tract are more common in individuals with FA.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1632414">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_382914" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Breast-ovarian cancer, familial, susceptibility to, 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_382625" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Breast-ovarian cancer, familial, susceptibility to, 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1632414" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fanconi anemia, complementation group S</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_325005" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lynch syndrome 4</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_318886" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lynch syndrome 5</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_231157" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Muir-Torré syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816697" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Premature ovarian failure 8</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_907624" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Thyroid cancer, nonmedullary, 4</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26411956">Management of Ovarian Cancer In Younger Women.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Uma Devi K,
Purushotham N,
Jayashree N</span><br />
<span class="medgenPMjournal">Rev Recent Clin Trials</span>
2015;10(4):263-9.
doi: 10.2174/1574887110666150923112047.
<span class="bold">PMID: </span><a href="/pubmed/26411956" target="_blank">26411956</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23942301">Angiogenesis as a target for the treatment of ovarian cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shaw D,
Clamp A,
Jayson GC</span><br />
<span class="medgenPMjournal">Curr Opin Oncol</span>
2013 Sep;25(5):558-65.
doi: 10.1097/CCO.0b013e328363e0da.
<span class="bold">PMID: </span><a href="/pubmed/23942301" target="_blank">23942301</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ovarian%20neoplasm%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (25)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</a></h3>
<h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/cg122" target="_blank">UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</a></h3>
</div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37787794">Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Minneci PC,
Bergus KC,
Lutz C,
Aldrink J,
Bence C,
Breech L,
Dillon PA,
Downard C,
Ehrlich PF,
Fallat M,
Fraser JD,
Grabowski J,
Helmrath M,
Hertweck P,
Hewitt G,
Hirschl RB,
Kabre R,
Lal DR,
Landman M,
Leys C,
Mak G,
Markel T,
Pressey J,
Raiji M,
Rymeski B,
Saito J,
Sato TT,
St Peter SD,
Cooper J,
Deans K;
Midwest Pediatric Surgery Consortium</span><br />
<span class="medgenPMjournal">JAMA</span>
2023 Oct 3;330(13):1247-1254.
doi: 10.1001/jama.2023.17183.
<span class="bold">PMID: </span><a href="/pubmed/37787794" target="_blank">37787794</a><a href="/pmc/articles/PMC10548301" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34846072">Ovarian Cystadenomas: Growth Rate and Reliability of Imaging Measurements.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Suh-Burgmann E,
Nakhaei M,
Gupta S,
Brook A,
Hecht J,
Hung YY,
Levine D</span><br />
<span class="medgenPMjournal">J Ultrasound Med</span>
2022 Sep;41(9):2157-2167.
Epub 2021 Nov 30
doi: 10.1002/jum.15895.
<span class="bold">PMID: </span><a href="/pubmed/34846072" target="_blank">34846072</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28668159">MR Imaging-Pathologic Correlation in Ovarian Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stein EB,
Wasnik AP,
Sciallis AP,
Kamaya A,
Maturen KE</span><br />
<span class="medgenPMjournal">Magn Reson Imaging Clin N Am</span>
2017 Aug;25(3):545-562.
Epub 2017 Apr 29
doi: 10.1016/j.mric.2017.03.004.
<span class="bold">PMID: </span><a href="/pubmed/28668159" target="_blank">28668159</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9228828">Ureteral injuries during gynecologic procedures.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mariotti G,
Natale F,
Trucchi A,
Cristini C,
Furbetta A</span><br />
<span class="medgenPMjournal">Minerva Urol Nefrol</span>
1997 Jun;49(2):95-8.
<span class="bold">PMID: </span><a href="/pubmed/9228828" target="_blank">9228828</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (269)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37787794">Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Minneci PC,
Bergus KC,
Lutz C,
Aldrink J,
Bence C,
Breech L,
Dillon PA,
Downard C,
Ehrlich PF,
Fallat M,
Fraser JD,
Grabowski J,
Helmrath M,
Hertweck P,
Hewitt G,
Hirschl RB,
Kabre R,
Lal DR,
Landman M,
Leys C,
Mak G,
Markel T,
Pressey J,
Raiji M,
Rymeski B,
Saito J,
Sato TT,
St Peter SD,
Cooper J,
Deans K;
Midwest Pediatric Surgery Consortium</span><br />
<span class="medgenPMjournal">JAMA</span>
2023 Oct 3;330(13):1247-1254.
doi: 10.1001/jama.2023.17183.
<span class="bold">PMID: </span><a href="/pubmed/37787794" target="_blank">37787794</a><a href="/pmc/articles/PMC10548301" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34928171">Brenner tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Costeira FS,
Félix A,
Cunha TM</span><br />
<span class="medgenPMjournal">Br J Radiol</span>
2022 Feb 1;95(1130):20210687.
Epub 2021 Dec 20
doi: 10.1259/bjr.20210687.
<span class="bold">PMID: </span><a href="/pubmed/34928171" target="_blank">34928171</a><a href="/pmc/articles/PMC8822556" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28668159">MR Imaging-Pathologic Correlation in Ovarian Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stein EB,
Wasnik AP,
Sciallis AP,
Kamaya A,
Maturen KE</span><br />
<span class="medgenPMjournal">Magn Reson Imaging Clin N Am</span>
2017 Aug;25(3):545-562.
Epub 2017 Apr 29
doi: 10.1016/j.mric.2017.03.004.
<span class="bold">PMID: </span><a href="/pubmed/28668159" target="_blank">28668159</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7296873">Endosalpingiosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Holmes MD,
Levin HS,
Ballard LA Jr</span><br />
<span class="medgenPMjournal">Cleve Clin Q</span>
1981 Fall;48(3):345-52.
doi: 10.3949/ccjm.48.3.345.
<span class="bold">PMID: </span><a href="/pubmed/7296873" target="_blank">7296873</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (381)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/37787794">Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Minneci PC,
Bergus KC,
Lutz C,
Aldrink J,
Bence C,
Breech L,
Dillon PA,
Downard C,
Ehrlich PF,
Fallat M,
Fraser JD,
Grabowski J,
Helmrath M,
Hertweck P,
Hewitt G,
Hirschl RB,
Kabre R,
Lal DR,
Landman M,
Leys C,
Mak G,
Markel T,
Pressey J,
Raiji M,
Rymeski B,
Saito J,
Sato TT,
St Peter SD,
Cooper J,
Deans K;
Midwest Pediatric Surgery Consortium</span><br />
<span class="medgenPMjournal">JAMA</span>
2023 Oct 3;330(13):1247-1254.
doi: 10.1001/jama.2023.17183.
<span class="bold">PMID: </span><a href="/pubmed/37787794" target="_blank">37787794</a><a href="/pmc/articles/PMC10548301" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34800494">Anesthesia strategy for factor X deficiency coagulopathy: case report.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ferreira CI,
Costa F,
Arantes AR,
Horta G,
Soares E,
Félix F</span><br />
<span class="medgenPMjournal">Braz J Anesthesiol</span>
2022 Nov-Dec;72(6):816-818.
Epub 2021 Nov 17
doi: 10.1016/j.bjane.2021.08.024.
<span class="bold">PMID: </span><a href="/pubmed/34800494" target="_blank">34800494</a><a href="/pmc/articles/PMC9660004" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26717495">Macroscopic deciduosis in pregnancy is finally a common entity.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Markou GA,
Goubin-Versini I,
Carbunaru OM,
Karatzios C,
Muray JM,
Fysekidis M</span><br />
<span class="medgenPMjournal">Eur J Obstet Gynecol Reprod Biol</span>
2016 Feb;197:54-8.
Epub 2015 Dec 2
doi: 10.1016/j.ejogrb.2015.11.036.
<span class="bold">PMID: </span><a href="/pubmed/26717495" target="_blank">26717495</a></div>
<div class="nl"><a target="_blank" href="/pubmed/4608334">Calcified metastases from malignant ovarian neoplasm. Review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moncada R,
Cooper RA,
Garces M,
Badrinath K</span><br />
<span class="medgenPMjournal">Radiology</span>
1974 Oct;113(1):31-5.
doi: 10.1148/113.1.31.
<span class="bold">PMID: </span><a href="/pubmed/4608334" target="_blank">4608334</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (121)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37787794">Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Minneci PC,
Bergus KC,
Lutz C,
Aldrink J,
Bence C,
Breech L,
Dillon PA,
Downard C,
Ehrlich PF,
Fallat M,
Fraser JD,
Grabowski J,
Helmrath M,
Hertweck P,
Hewitt G,
Hirschl RB,
Kabre R,
Lal DR,
Landman M,
Leys C,
Mak G,
Markel T,
Pressey J,
Raiji M,
Rymeski B,
Saito J,
Sato TT,
St Peter SD,
Cooper J,
Deans K;
Midwest Pediatric Surgery Consortium</span><br />
<span class="medgenPMjournal">JAMA</span>
2023 Oct 3;330(13):1247-1254.
doi: 10.1001/jama.2023.17183.
<span class="bold">PMID: </span><a href="/pubmed/37787794" target="_blank">37787794</a><a href="/pmc/articles/PMC10548301" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36497095">cAMP-Dependent Signaling and Ovarian Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kilanowska A,
Ziółkowska A,
Stasiak P,
Gibas-Dorna M</span><br />
<span class="medgenPMjournal">Cells</span>
2022 Nov 29;11(23)
doi: 10.3390/cells11233835.
<span class="bold">PMID: </span><a href="/pubmed/36497095" target="_blank">36497095</a><a href="/pmc/articles/PMC9738761" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27770228">ESUR recommendations for MR imaging of the sonographically indeterminate adnexal mass: an update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Forstner R,
Thomassin-Naggara I,
Cunha TM,
Kinkel K,
Masselli G,
Kubik-Huch R,
Spencer JA,
Rockall A</span><br />
<span class="medgenPMjournal">Eur Radiol</span>
2017 Jun;27(6):2248-2257.
Epub 2016 Oct 21
doi: 10.1007/s00330-016-4600-3.
<span class="bold">PMID: </span><a href="/pubmed/27770228" target="_blank">27770228</a><a href="/pmc/articles/PMC5408043" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25614393">Usefulness of diagnostic indices comprising clinical, sonographic, and biomarker data for discriminating benign from malignant ovarian masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stukan M,
Dudziak M,
Ratajczak K,
Grabowski JP</span><br />
<span class="medgenPMjournal">J Ultrasound Med</span>
2015 Feb;34(2):207-17.
doi: 10.7863/ultra.34.2.207.
<span class="bold">PMID: </span><a href="/pubmed/25614393" target="_blank">25614393</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (201)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37787794">Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Minneci PC,
Bergus KC,
Lutz C,
Aldrink J,
Bence C,
Breech L,
Dillon PA,
Downard C,
Ehrlich PF,
Fallat M,
Fraser JD,
Grabowski J,
Helmrath M,
Hertweck P,
Hewitt G,
Hirschl RB,
Kabre R,
Lal DR,
Landman M,
Leys C,
Mak G,
Markel T,
Pressey J,
Raiji M,
Rymeski B,
Saito J,
Sato TT,
St Peter SD,
Cooper J,
Deans K;
Midwest Pediatric Surgery Consortium</span><br />
<span class="medgenPMjournal">JAMA</span>
2023 Oct 3;330(13):1247-1254.
doi: 10.1001/jama.2023.17183.
<span class="bold">PMID: </span><a href="/pubmed/37787794" target="_blank">37787794</a><a href="/pmc/articles/PMC10548301" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34846072">Ovarian Cystadenomas: Growth Rate and Reliability of Imaging Measurements.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Suh-Burgmann E,
Nakhaei M,
Gupta S,
Brook A,
Hecht J,
Hung YY,
Levine D</span><br />
<span class="medgenPMjournal">J Ultrasound Med</span>
2022 Sep;41(9):2157-2167.
Epub 2021 Nov 30
doi: 10.1002/jum.15895.
<span class="bold">PMID: </span><a href="/pubmed/34846072" target="_blank">34846072</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32736853">Guideline No. 403: Initial Investigation and Management of Adnexal Masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salvador S,
Scott S,
Glanc P,
Eiriksson L,
Jang JH,
Sebastianelli A,
Dean E</span><br />
<span class="medgenPMjournal">J Obstet Gynaecol Can</span>
2020 Aug;42(8):1021-1029.e3.
doi: 10.1016/j.jogc.2019.08.044.
<span class="bold">PMID: </span><a href="/pubmed/32736853" target="_blank">32736853</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27770228">ESUR recommendations for MR imaging of the sonographically indeterminate adnexal mass: an update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Forstner R,
Thomassin-Naggara I,
Cunha TM,
Kinkel K,
Masselli G,
Kubik-Huch R,
Spencer JA,
Rockall A</span><br />
<span class="medgenPMjournal">Eur Radiol</span>
2017 Jun;27(6):2248-2257.
Epub 2016 Oct 21
doi: 10.1007/s00330-016-4600-3.
<span class="bold">PMID: </span><a href="/pubmed/27770228" target="_blank">27770228</a><a href="/pmc/articles/PMC5408043" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25614393">Usefulness of diagnostic indices comprising clinical, sonographic, and biomarker data for discriminating benign from malignant ovarian masses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stukan M,
Dudziak M,
Ratajczak K,
Grabowski JP</span><br />
<span class="medgenPMjournal">J Ultrasound Med</span>
2015 Feb;34(2):207-17.
doi: 10.7863/ultra.34.2.207.
<span class="bold">PMID: </span><a href="/pubmed/25614393" target="_blank">25614393</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (168)</a></div></div>
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<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/38438776">Histologic Subtypes in Endometriosis-Associated Ovarian Cancer and Ovarian Cancer Arising in Endometriosis: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chiaffarino F,
Cipriani S,
Ricci E,
Esposito G,
Parazzini F,
Vercellini P</span><br />
<span class="medgenPMjournal">Reprod Sci</span>
2024 Jun;31(6):1642-1650.
Epub 2024 Mar 4
doi: 10.1007/s43032-024-01489-9.
<span class="bold">PMID: </span><a href="/pubmed/38438776" target="_blank">38438776</a><a href="/pmc/articles/PMC11111532" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38030996">Effects of epidural anesthesia on the prognosis of ovarian cancer-a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shen H,
Pang Q,
Gao Y,
Liu H</span><br />
<span class="medgenPMjournal">BMC Anesthesiol</span>
2023 Nov 29;23(1):390.
doi: 10.1186/s12871-023-02352-1.
<span class="bold">PMID: </span><a href="/pubmed/38030996" target="_blank">38030996</a><a href="/pmc/articles/PMC10685604" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35384414">Anthropometric factors and the risk of ovarian cancer: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ellwanger B,
Schüler-Toprak S,
Jochem C,
Leitzmann MF,
Baurecht H</span><br />
<span class="medgenPMjournal">Cancer Rep (Hoboken)</span>
2022 Nov;5(11):e1618.
Epub 2022 Apr 5
doi: 10.1002/cnr2.1618.
<span class="bold">PMID: </span><a href="/pubmed/35384414" target="_blank">35384414</a><a href="/pmc/articles/PMC9675384" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35112281">Association Between the Frequent Use of Perineal Talcum Powder Products and Ovarian Cancer: a Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Woolen SA,
Lazar AA,
Smith-Bindman R</span><br />
<span class="medgenPMjournal">J Gen Intern Med</span>
2022 Aug;37(10):2526-2532.
Epub 2022 Feb 2
doi: 10.1007/s11606-022-07414-7.
<span class="bold">PMID: </span><a href="/pubmed/35112281" target="_blank">35112281</a><a href="/pmc/articles/PMC9360263" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28720017">Obesity and ovarian cancer risk: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Foong KW,
Bolton H</span><br />
<span class="medgenPMjournal">Post Reprod Health</span>
2017 Dec;23(4):183-198.
Epub 2017 Jul 18
doi: 10.1177/2053369117709225.
<span class="bold">PMID: </span><a href="/pubmed/28720017" target="_blank">28720017</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ovarian%20neoplasm%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul id="my-toc"></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (90)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F29" target="_blank">Detection of homozygosity (1)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A3%5F31" target="_blank">Fluorescence in situ hybridization (FISH) (1)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F18" target="_blank">Mutation scanning of select exons (1)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F17" target="_blank">Mutation scanning of the entire coding region (1)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F30" target="_blank">RNA analysis (4)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F9" target="_blank">Sequence analysis of select exons (4)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (97)</a></li>
<li><a href="/gtr/tests?term=C0919267%5bDISCUI%5d&amp;filter=method%3A2%5F19" target="_blank">Targeted variant analysis (10)</a></li>
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0919267%5bDISCUI%5d" target="_blank">See all (112)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Ovarian%20neoplasm" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ovarian%20neoplasm%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Ovarian%20neoplasm%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/ovarian.pdf">NCCN, 2024</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer, 2024</div></li><li><a target="_blank" href="https://www.nice.org.uk/guidance/cg122">NICE, 2023</a><div>UK NICE Clinical guideline (CG122), Ovarian cancer: recognition and initial management, 2023</div></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&amp;query=Ovarian%20neoplasm" target="_blank">MedlinePlus</a></li></ul></div>
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