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<!--
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||
UID=1635115
|
||
ConceptID=C4554344
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Food allergy</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1635115</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4554344</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>allergic disease from food material; Allergic reaction to foods; allergy of food material; food allergy; food hypersensitivity; food material allergic disease; IgE-mediated food allergy; Immunoglobulin E-mediated food allergy; Reaction to food allergens</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0500093">HP:0500093</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
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<td><a href="https://monarchinitiative.org/disease/MONDO:0700226" target="_blank">MONDO:0700226</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Primary food allergies primarily occur as a result (most likely) of gastrointestinal sensitization to predominantly stable food allergens (glycoproteins). A secondary food allergy develops after primary sensitization to airborne allergens (e. g., pollen allergens) with subsequent reactions (due to cross-reactivity) to structurally related often labile allergens in (plant) foods. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Food allergy</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/232638" ref="tree=MeSH" title="MedGen record for Immune System and Related Disorders">Immune System and Related Disorders</a></span><ul><li><span class="TLline"><a href="/medgen/5759" ref="tree=MeSH" title="MedGen record for Immune system disorder">Immune system disorder</a></span><ul><li><span class="TLline"><a href="/medgen/9370" ref="tree=MeSH" title="MedGen record for Allergy">Allergy</a></span><ul><li><span class="matched_ds">Food allergy</span><ul><li><span class="TLline"><a href="/medgen/1705383" ref="tree=MeSH" title="MedGen record for Dairy allergy">Dairy allergy</a></span><ul><li><span class="TLline"><a href="/medgen/1668719" ref="tree=MeSH" title="MedGen record for Cow milk allergy">Cow milk allergy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/108241" ref="tree=MeSH" title="MedGen record for Egg allergy">Egg allergy</a></span></li><li><span class="TLline"><a href="/medgen/1698538" ref="tree=MeSH" title="MedGen record for Gluten allergy">Gluten allergy</a></span></li><li><span class="TLline"><a href="/medgen/844468" ref="tree=MeSH" title="MedGen record for Meat allergen allergy">Meat allergen allergy</a></span></li><li><span class="TLline"><a href="/medgen/1700974" ref="tree=MeSH" title="MedGen record for Plant based food allergy">Plant based food allergy</a></span><ul><li><span class="TLline"><a href="/medgen/108401" ref="tree=MeSH" title="MedGen record for Nut food product allergy">Nut food product allergy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/672821" ref="tree=MeSH" title="MedGen record for Seafood allergy">Seafood allergy</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_83339"><div><strong>Insulin-dependent diabetes mellitus secretory diarrhea syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>83339</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0342288</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome is characterized by systemic autoimmunity, typically beginning in the first year of life, which includes the triad of enteropathy (manifesting as malabsorption and watery diarrhea), endocrinopathy (most commonly type 1 insulin-dependent diabetes mellitus), and eczematous dermatitis. In addition to these manifestations, many children have other autoimmune phenomena including cytopenias, autoimmune hepatitis, nephropathy, lymphadenopathy, splenomegaly, alopecia, arthritis, and interstitial lung disease related to immune dysregulation. Fetal presentation of IPEX syndrome includes hydrops, echogenic bowel, skin desquamation, intrauterine growth deficiency, and fetal akinesia. Without aggressive immunosuppression or hematopoietic stem cell transplantation (HSCT), the majority of affected males will die within the first one to two years of life from metabolic derangements, severe malabsorption, or sepsis. Individuals with a milder phenotype have survived into the second or third decade of life, but this is uncommon.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/83339">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324839"><div><strong>Ichthyosis prematurity syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324839</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1837610</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Ichthyosis prematurity syndrome (IPS) is a rare subtype of autosomal recessive congenital ichthyosis, a clinically and genetically heterogeneous group of inherited keratinization disorders. IPS presents with complications at midtrimester of pregnancy leading to prematurity, a thick caseous and desquamating skin, respiratory complications, and persistent eosinophilia. Skin features evolve into a flat follicular hyperkeratosis with atopy (Klar et al., 2004).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/324839">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_816049"><div><strong>Severe dermatitis-multiple allergies-metabolic wasting syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816049</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809719</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare genetic epidermal disorder with characteristics of congenital erythroderma with severe psoriasiform dermatitis, ichthyosis, severe palmoplantar keratoderma, yellow keratosis on the hands and feet, elevated immunoglobulin E, multiple food allergies, and metabolic wasting. Other variable features may include hypotrichosis, nail dystrophy, recurrent infections, mild global developmental delay, eosinophilia, nystagmus, growth impairment and cardiac defects.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/816049">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_862808"><div><strong>Immunodeficiency 23</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>862808</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4014371</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">IMD23 is an autosomal recessive primary immunodeficiency syndrome characterized by onset of recurrent infections, usually respiratory or cutaneous, in early childhood. Immune workup usually shows neutropenia, lymphopenia, eosinophilia, and increased serum IgE or IgA. Neutrophil chemotactic defects have also been reported. Infectious agents include bacteria, viruses, and fungi. Many patients develop atopic dermatitis, eczema, and other signs of autoinflammation. Affected individuals may also show developmental delay or cognitive impairment of varying severity (summary by Bjorksten and Lundmark, 1976 and Zhang et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/862808">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1627819"><div><strong>Immunodeficiency 11b with atopic dermatitis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1627819</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4539957</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">IMD11B is an autosomal dominant disorder of immune dysfunction characterized by onset of moderate to severe atopic dermatitis in early childhood. Some patients may have recurrent infections and other variable immune abnormalities. Laboratory studies show defects in T-cell activation, increased IgE, and eosinophilia (summary by Ma et al., 2017).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1627819">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1614787"><div><strong>Intellectual disability, autosomal dominant 54</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1614787</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4540484</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1614787">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648410"><div><strong>Combined immunodeficiency due to DOCK8 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648410</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4722305</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-2 with recurrent infections (HIES2) is an autosomal recessive immunologic disorder characterized by recurrent staphylococcal infections of the skin and respiratory tract, eczema, elevated serum immunoglobulin E, and hypereosinophilia. It is distinguished from autosomal dominant HIES1 (147060) by the lack of connective tissue and skeletal involvement (Renner et al., 2004). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see 147060. See also TYK2 deficiency (611521), a clinically distinct disease entity that includes characteristic features of both autosomal recessive HIES2 and mendelian susceptibility to mycobacterial disease (MSMD; 209950) (Minegishi et al., 2006).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648410">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1673363"><div><strong>Hyper-IgE recurrent infection syndrome 4, autosomal recessive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1673363</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5193141</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-4B with recurrent infections (HIES4B) is an autosomal recessive immunologic disorder characterized by early childhood onset of recurrent infections and skeletal abnormalities, including craniosynostosis and scoliosis. Patients are mainly susceptible to bacterial infections that affect the respiratory tract, skin, and eye. Immunologic workup shows increased serum IgE, intermittent eosinophilia, and impaired IL6 (147620) and IL27 (608273) downstream signaling that affects the development and function of certain B- and T-cell populations, as well as the acute-phase response; IL11 (147681) signaling in fibroblasts is also affected (summary by Shahin et al., 2019). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see HIES1 (147060).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1673363">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1724999"><div><strong>Tolchin-Le Caignec syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1724999</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436509</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Tolchin-Le Caignec syndrome (TOLCAS) is a developmental disorder characterized by mildly to moderately impaired intellectual development and behavioral problems, such as autism, ADHD, labile mood, and aggressive episodes. Many patients have bony abnormalities, including osteochondroma, craniosynostosis, dysmorphic facies, arachnodactyly, and large head circumference. Rarely, additional congenital anomalies may also be observed. These additional features and the bony defects are highly variable (summary by Tolchin et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1724999">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1750270"><div><strong>Autoinflammation, immune dysregulation, and eosinophilia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1750270</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436572</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autoinflammation, immune dysregulation, and eosinophilia (AIIDE) is an autosomal dominant disorder characterized by onset of severe atopic dermatitis and chronic gastrointestinal inflammation, mainly involving the colon, in infancy or early childhood. Affected individuals tend to have asthma and food or environmental allergies, as well as poor overall growth with short stature. Severe liver involvement has also been reported (Takeichi et al., 2021). Laboratory studies show increased eosinophils with normal or increased IgE levels, as well as evidence of a hyperactive immune state, including increased erythrocyte sedimentation rate and C-reactive protein. Treatment with JAK inhibitors, such as ruxolitinib and tofacitinib, results in dramatic clinical improvement (summary by Gruber et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1750270">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1794167"><div><strong>Developmental delay, impaired speech, and behavioral abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794167</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5561957</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Developmental delay, impaired speech, and behavioral abnormalities (DDISBA) is characterized by global developmental delay apparent from early childhood. Intellectual disability can range from mild to severe. Additional variable features may include dysmorphic facial features, seizures, hypotonia, motor abnormalities such as Tourette syndrome or dystonia, and hearing loss (summary by Cousin et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1794167">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1802991"><div><strong>Netherton syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1802991</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5574950</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Netherton syndrome (NETH) is a rare and severe autosomal recessive skin disorder characterized by congenital erythroderma, a specific hair-shaft abnormality, and atopic manifestations with high IgE levels. Generalized scaly erythroderma is apparent at or soon after birth and usually persists. Scalp hair is sparse and brittle with a characteristic 'bamboo' shape under light microscopic examination due to invagination of the distal part of the hair shaft to its proximal part. Atopic manifestations include eczema-like rashes, atopic dermatitis, pruritus, hay fever, angioedema, urticaria, high levels of IgE in the serum, and hypereosinophilia. Life-threatening complications are frequent during the neonatal period, including hypernatremic dehydration, hypothermia, extreme weight loss, bronchopneumonia, and sepsis. During childhood, failure to thrive is common as a result of malnutrition, metabolic disorders, chronic erythroderma, persistent cutaneous infections, or enteropathy (summary by Bitoun et al., 2002).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1802991">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1808193"><div><strong>Intellectual disability and myopathy syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1808193</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676904</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Intellectual disability and myopathy syndrome (IDMYS) is an autosomal recessive developmental disorder characterized by global developmental delay with mildly impaired intellectual development, hypotonia, muscle weakness and fatigue, and white matter abnormalities on brain imaging. Variable additional features may include sensorineural hearing loss, dysmorphic facies, and progressive heart disease (summary by Smeland et al., 2019).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1808193">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1809613"><div><strong>Hyper-IgE recurrent infection syndrome 4A, autosomal dominant</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1809613</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676920</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-4A with recurrent infections (HIES4A) is an autosomal dominant immunologic disorder characterized by recurrent, mainly sinopulmonary infections associated with increased serum IgE. The phenotype is variable, even within families. Some patients have onset of symptoms in early childhood and develop complications, including bronchiectasis or hemoptysis, whereas others have later onset of less severe infections. Immunologic workup usually shows normal leukocyte levels, although some patients may demonstrate alterations in lymphocyte subsets, including T cells. Affected individuals also have variable skeletal abnormalities, including high-arched palate, hyperextensible joints, scoliosis, and bone fractures. The IL6ST mutations are loss-of-function, although the truncated mutant proteins are expressed and interfere with the wildtype protein in a dominant-negative manner by disrupting IL6 (147620) and IL11 (147681) signaling (summary by Beziat et al., 2020). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see HIES1 (147060).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1809613">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1851769"><div><strong>Hyper-IgE syndrome 6, autosomal dominant, with recurrent infections</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1851769</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5848786</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hyper-IgE syndrome-6 with recurrent infections (HIES6) is an autosomal dominant immunologic disorder characterized by early-childhood onset of severe refractory atopic dermatitis, IgE-mediated food and drug allergies, asthma, and eosinophilic esophagitis. Laboratory studies show increased serum IgE levels and eosinophilia. Affected individuals are susceptible to life-threatening anaphylaxis. Additional features may include allergic rhinitis, recurrent secondary infections (bacterial, viral, fungal), and short stature. Rare patients show intracerebral vascular abnormalities, including the Circle of Willis, increased risk of ruptured aneurysm, and B-cell lymphoma. The disorder results from immune dysregulation with inappropriate activation of inflammatory signaling pathways associated with a Th2 phenotype. Treatment with an IL4 (147780)/IL13 (147683) inhibitor (dupilumab) or JAK inhibitor results in clinical improvement. Sharma et al. (2023) classified this disease as a 'primary atopic disorder' (PAD). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see HIES1 (147060).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1851769">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1848890"><div><strong>Immunodeficiency 114, folate-responsive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1848890</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882719</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Folate-responsive immunodeficiency-114 (IMD114) is an autosomal recessive immunologic disorder characterized by the onset of oral ulcers and recurrent skin and respiratory infections in early infancy. Affected individuals have lip fissures, skin sores and abscesses, genital dermatitis, chronic diarrhea, and poor overall growth. Laboratory studies show megaloblastic anemia, thrombocytopenia, and lymphopenia with decreased Ig levels. Some individuals have global developmental delay, often with brain imaging abnormalities. Treatment with folic acid supplementation results in significant clinical improvement of the hematologic and immunologic abnormalities, although neurologic abnormalities, if already present, do not respond to treatment. Early intervention and treatment with folic acid supplementation may prevent or delay neurologic deficits in affected infants (Gok et al., 2023; Shiraishi et al., 2023).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1848890">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1860800"><div><strong>Immunodeficiency 122</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1860800</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935632</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-122 (IMD122) is an autosomal recessive inborn error of immunity characterized by early-infantile onset of recurrent viral and bacterial infections of the respiratory tract and skin. Laboratory studies show severely decreased CD3+ T cells particularly affecting naive T cells, impaired early TCR recombination with a restricted TCR repertoire, normal or low-normal B cells, and decreased or increased NK cells. Affected individuals have poor overall growth, global developmental delay with poor motor skills, impaired intellectual development, and poor or absent speech acquisition. More variable findings may include diffuse skin rash, erythroderma, sensorineural hearing loss, lymphadenopathy, dysmorphic facial features, and tooth abnormalities. Death in early childhood may occur (Mehawej et al., 2023; Riestra et al., 2024).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1860800">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1750270" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autoinflammation, immune dysregulation, and eosinophilia</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648410" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to DOCK8 deficiency</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794167" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Developmental delay, impaired speech, and behavioral abnormalities</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1673363" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyper-IgE recurrent infection syndrome 4, autosomal recessive</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1809613" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyper-IgE recurrent infection syndrome 4A, autosomal dominant</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (17)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1851769" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyper-IgE syndrome 6, autosomal dominant, with recurrent infections</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324839" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ichthyosis prematurity syndrome</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1848890" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 114, folate-responsive</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1627819" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 11b with atopic dermatitis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1860800" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 122</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_862808" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 23</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_83339" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Insulin-dependent diabetes mellitus secretory diarrhea syndrome</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1808193" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability and myopathy syndrome</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1614787" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability, autosomal dominant 54</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1802991" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Netherton syndrome</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816049" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severe dermatitis-multiple allergies-metabolic wasting syndrome</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1724999" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tolchin-Le Caignec syndrome</a></div></span></div></div>
|
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/36878860">International consensus statement on allergy and rhinology: Allergic rhinitis - 2023.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wise SK,
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Damask C,
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Roland LT,
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Ebert C,
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Levy JM,
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Luong A,
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Rodriguez K,
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Sedaghat AR,
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Toskala E,
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Villwock J,
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Akdis C,
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Alt JA,
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Azar A,
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Brook C,
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Chew FT,
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Davis EM,
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Kuan EC,
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Lang D,
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Larenas-Linnemann D,
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Laury AM,
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Lechner M,
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Lee SE,
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Lee VS,
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Loftus P,
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Marcus S,
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Marzouk H,
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Mattos J,
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McCoul E,
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Melen E,
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Mims JW,
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Mullol J,
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Nayak JV,
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Oppenheimer J,
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Orlandi RR,
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Phillips K,
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Platt M,
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Ramanathan M Jr,
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Raymond M,
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Rhee CS,
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Reitsma S,
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Ryan M,
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Sastre J,
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Schlosser RJ,
|
||
Schuman TA,
|
||
Shaker MS,
|
||
Sheikh A,
|
||
Smith KA,
|
||
Soyka MB,
|
||
Takashima M,
|
||
Tang M,
|
||
Tantilipikorn P,
|
||
Taw MB,
|
||
Tversky J,
|
||
Tyler MA,
|
||
Veling MC,
|
||
Wallace D,
|
||
Wang Y,
|
||
White A,
|
||
Zhang L</span><br />
|
||
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
|
||
2023 Apr;13(4):293-859.
|
||
Epub 2023 Mar 6
|
||
doi: 10.1002/alr.23090.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36878860" target="_blank">36878860</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32707227">Rhinitis 2020: A practice parameter update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dykewicz MS,
|
||
Wallace DV,
|
||
Amrol DJ,
|
||
Baroody FM,
|
||
Bernstein JA,
|
||
Craig TJ,
|
||
Dinakar C,
|
||
Ellis AK,
|
||
Finegold I,
|
||
Golden DBK,
|
||
Greenhawt MJ,
|
||
Hagan JB,
|
||
Horner CC,
|
||
Khan DA,
|
||
Lang DM,
|
||
Larenas-Linnemann DES,
|
||
Lieberman JA,
|
||
Meltzer EO,
|
||
Oppenheimer JJ,
|
||
Rank MA,
|
||
Shaker MS,
|
||
Shaw JL,
|
||
Steven GC,
|
||
Stukus DR,
|
||
Wang J;
|
||
Chief Editor(s):,
|
||
Dykewicz MS,
|
||
Wallace DV;
|
||
Joint Task Force on Practice Parameters:,
|
||
Dinakar C,
|
||
Ellis AK,
|
||
Golden DBK,
|
||
Greenhawt MJ,
|
||
Horner CC,
|
||
Khan DA,
|
||
Lang DM,
|
||
Lieberman JA,
|
||
Oppenheimer JJ,
|
||
Rank MA,
|
||
Shaker MS,
|
||
Stukus DR,
|
||
Wang J;
|
||
Workgroup Contributors:,
|
||
Dykewicz MS,
|
||
Wallace DV,
|
||
Amrol DJ,
|
||
Baroody FM,
|
||
Bernstein JA,
|
||
Craig TJ,
|
||
Finegold I,
|
||
Hagan JB,
|
||
Larenas-Linnemann DES,
|
||
Meltzer EO,
|
||
Shaw JL,
|
||
Steven GC</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
|
||
2020 Oct;146(4):721-767.
|
||
Epub 2020 Jul 22
|
||
doi: 10.1016/j.jaci.2020.07.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32707227" target="_blank">32707227</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29157945">Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Sampson HA</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
|
||
2018 Jan;141(1):41-58.
|
||
Epub 2017 Nov 21
|
||
doi: 10.1016/j.jaci.2017.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29157945" target="_blank">29157945</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22food%20allergy%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (669)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33370488">Update on food allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peters RL,
|
||
Krawiec M,
|
||
Koplin JJ,
|
||
Santos AF</span><br />
|
||
<span class="medgenPMjournal">Pediatr Allergy Immunol</span>
|
||
2021 May;32(4):647-657.
|
||
Epub 2021 Jan 21
|
||
doi: 10.1111/pai.13443.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33370488" target="_blank">33370488</a><a href="/pmc/articles/PMC8247869" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32499034">Food Allergy from Infancy Through Adulthood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Warren CM,
|
||
Dant C,
|
||
Gupta RS,
|
||
Nadeau KC</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2020 Jun;8(6):1854-1864.
|
||
doi: 10.1016/j.jaip.2020.02.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32499034" target="_blank">32499034</a><a href="/pmc/articles/PMC7899184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32067114">Epidemiology and Burden of Food Allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Warren CM,
|
||
Jiang J,
|
||
Gupta RS</span><br />
|
||
<span class="medgenPMjournal">Curr Allergy Asthma Rep</span>
|
||
2020 Feb 14;20(2):6.
|
||
doi: 10.1007/s11882-020-0898-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32067114" target="_blank">32067114</a><a href="/pmc/articles/PMC7883751" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31930423">Food Allergy: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Seth D,
|
||
Poowutikul P,
|
||
Pansare M,
|
||
Kamat D</span><br />
|
||
<span class="medgenPMjournal">Pediatr Ann</span>
|
||
2020 Jan 1;49(1):e50-e58.
|
||
doi: 10.3928/19382359-20191206-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31930423" target="_blank">31930423</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29157945">Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Sampson HA</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
|
||
2018 Jan;141(1):41-58.
|
||
Epub 2017 Nov 21
|
||
doi: 10.1016/j.jaci.2017.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29157945" target="_blank">29157945</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4242)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34875122">Food allergy and hypersensitivity reactions in children and adults-A review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tedner SG,
|
||
Asarnoj A,
|
||
Thulin H,
|
||
Westman M,
|
||
Konradsen JR,
|
||
Nilsson C</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2022 Mar;291(3):283-302.
|
||
Epub 2021 Dec 22
|
||
doi: 10.1111/joim.13422.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34875122" target="_blank">34875122</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33370488">Update on food allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peters RL,
|
||
Krawiec M,
|
||
Koplin JJ,
|
||
Santos AF</span><br />
|
||
<span class="medgenPMjournal">Pediatr Allergy Immunol</span>
|
||
2021 May;32(4):647-657.
|
||
Epub 2021 Jan 21
|
||
doi: 10.1111/pai.13443.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33370488" target="_blank">33370488</a><a href="/pmc/articles/PMC8247869" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32499034">Food Allergy from Infancy Through Adulthood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Warren CM,
|
||
Dant C,
|
||
Gupta RS,
|
||
Nadeau KC</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2020 Jun;8(6):1854-1864.
|
||
doi: 10.1016/j.jaip.2020.02.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32499034" target="_blank">32499034</a><a href="/pmc/articles/PMC7899184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31930423">Food Allergy: A Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Seth D,
|
||
Poowutikul P,
|
||
Pansare M,
|
||
Kamat D</span><br />
|
||
<span class="medgenPMjournal">Pediatr Ann</span>
|
||
2020 Jan 1;49(1):e50-e58.
|
||
doi: 10.3928/19382359-20191206-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31930423" target="_blank">31930423</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29157945">Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Sampson HA</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
|
||
2018 Jan;141(1):41-58.
|
||
Epub 2017 Nov 21
|
||
doi: 10.1016/j.jaci.2017.11.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29157945" target="_blank">29157945</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4516)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38009299">Systematic review and meta-analyses on the accuracy of diagnostic tests for IgE-mediated food allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Riggioni C,
|
||
Ricci C,
|
||
Moya B,
|
||
Wong D,
|
||
van Goor E,
|
||
Bartha I,
|
||
Buyuktiryaki B,
|
||
Giovannini M,
|
||
Jayasinghe S,
|
||
Jaumdally H,
|
||
Marques-Mejias A,
|
||
Piletta-Zanin A,
|
||
Berbenyuk A,
|
||
Andreeva M,
|
||
Levina D,
|
||
Iakovleva E,
|
||
Roberts G,
|
||
Chu D,
|
||
Peters R,
|
||
du Toit G,
|
||
Skypala I,
|
||
Santos AF</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2024 Feb;79(2):324-352.
|
||
Epub 2023 Nov 27
|
||
doi: 10.1111/all.15939.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38009299" target="_blank">38009299</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37105602">Food Allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mendonca CE,
|
||
Andreae DA</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2023 Jun;50(2):205-220.
|
||
Epub 2023 Mar 27
|
||
doi: 10.1016/j.pop.2023.01.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37105602" target="_blank">37105602</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36529441">Omalizumab in IgE-Mediated Food Allergy: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zuberbier T,
|
||
Wood RA,
|
||
Bindslev-Jensen C,
|
||
Fiocchi A,
|
||
Chinthrajah RS,
|
||
Worm M,
|
||
Deschildre A,
|
||
Fernandez-Rivas M,
|
||
Santos AF,
|
||
Jaumont X,
|
||
Tassinari P</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2023 Apr;11(4):1134-1146.
|
||
Epub 2022 Dec 15
|
||
doi: 10.1016/j.jaip.2022.11.036.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36529441" target="_blank">36529441</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32419030">Prevention of Atopic Dermatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Williams HC,
|
||
Chalmers J</span><br />
|
||
<span class="medgenPMjournal">Acta Derm Venereol</span>
|
||
2020 Jun 9;100(12):adv00166.
|
||
doi: 10.2340/00015555-3516.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32419030" target="_blank">32419030</a><a href="/pmc/articles/PMC9189742" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32396244">Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Silva D,
|
||
Halken S,
|
||
Singh C,
|
||
Muraro A,
|
||
Angier E,
|
||
Arasi S,
|
||
Arshad H,
|
||
Beyer K,
|
||
Boyle R,
|
||
du Toit G,
|
||
Eigenmann P,
|
||
Grimshaw K,
|
||
Hoest A,
|
||
Jones C,
|
||
Khaleva E,
|
||
Lack G,
|
||
Szajewska H,
|
||
Venter C,
|
||
Verhasselt V,
|
||
Roberts G;
|
||
European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group</span><br />
|
||
<span class="medgenPMjournal">Pediatr Allergy Immunol</span>
|
||
2020 Oct;31(7):813-826.
|
||
Epub 2020 Jun 18
|
||
doi: 10.1111/pai.13273.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32396244" target="_blank">32396244</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3734)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32973790">Research Progress in Atopic March.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang L,
|
||
Fu J,
|
||
Zhou Y</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2020;11:1907.
|
||
Epub 2020 Aug 27
|
||
doi: 10.3389/fimmu.2020.01907.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32973790" target="_blank">32973790</a><a href="/pmc/articles/PMC7482645" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/32499034">Food Allergy from Infancy Through Adulthood.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
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Warren CM,
|
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Dant C,
|
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Gupta RS,
|
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Nadeau KC</span><br />
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<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
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2020 Jun;8(6):1854-1864.
|
||
doi: 10.1016/j.jaip.2020.02.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32499034" target="_blank">32499034</a><a href="/pmc/articles/PMC7899184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32143431">Immunoglobulin E (IgE)-Mediated Food Allergy in Children: Epidemiology, Pathogenesis, Diagnosis, Prevention, and Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barni S,
|
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Liccioli G,
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Sarti L,
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Giovannini M,
|
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Novembre E,
|
||
Mori F</span><br />
|
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<span class="medgenPMjournal">Medicina (Kaunas)</span>
|
||
2020 Mar 4;56(3)
|
||
doi: 10.3390/medicina56030111.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32143431" target="_blank">32143431</a><a href="/pmc/articles/PMC7142605" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29132679">Food Allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bird JA</span><br />
|
||
<span class="medgenPMjournal">Immunol Allergy Clin North Am</span>
|
||
2018 Feb;38(1):xv-xvi.
|
||
doi: 10.1016/j.iac.2017.10.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29132679" target="_blank">29132679</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24388012">Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
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Sampson HA</span><br />
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<span class="medgenPMjournal">J Allergy Clin Immunol</span>
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2014 Feb;133(2):291-307; quiz 308.
|
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Epub 2013 Dec 31
|
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doi: 10.1016/j.jaci.2013.11.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24388012" target="_blank">24388012</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1573)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33429723">Improving Diagnostic Accuracy in Food Allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Foong RX,
|
||
Dantzer JA,
|
||
Wood RA,
|
||
Santos AF</span><br />
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||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2021 Jan;9(1):71-80.
|
||
doi: 10.1016/j.jaip.2020.09.037.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33429723" target="_blank">33429723</a><a href="/pmc/articles/PMC7794657" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32499034">Food Allergy from Infancy Through Adulthood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Warren CM,
|
||
Dant C,
|
||
Gupta RS,
|
||
Nadeau KC</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2020 Jun;8(6):1854-1864.
|
||
doi: 10.1016/j.jaip.2020.02.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32499034" target="_blank">32499034</a><a href="/pmc/articles/PMC7899184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25680669">Food allergies: the basics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Valenta R,
|
||
Hochwallner H,
|
||
Linhart B,
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||
Pahr S</span><br />
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<span class="medgenPMjournal">Gastroenterology</span>
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2015 May;148(6):1120-31.e4.
|
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Epub 2015 Feb 11
|
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doi: 10.1053/j.gastro.2015.02.006.
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<span class="bold">PMID: </span><a href="/pubmed/25680669" target="_blank">25680669</a><a href="/pmc/articles/PMC4414527" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24388012">Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sicherer SH,
|
||
Sampson HA</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
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||
2014 Feb;133(2):291-307; quiz 308.
|
||
Epub 2013 Dec 31
|
||
doi: 10.1016/j.jaci.2013.11.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24388012" target="_blank">24388012</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18799559">Clinical practice. Food allergy.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Lack G</span><br />
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<span class="medgenPMjournal">N Engl J Med</span>
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2008 Sep 18;359(12):1252-60.
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doi: 10.1056/NEJMcp0800871.
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<span class="bold">PMID: </span><a href="/pubmed/18799559" target="_blank">18799559</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2298)</a></div></div>
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||
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|
||
|
||
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38009299">Systematic review and meta-analyses on the accuracy of diagnostic tests for IgE-mediated food allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Riggioni C,
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Ricci C,
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Moya B,
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Wong D,
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van Goor E,
|
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Bartha I,
|
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Buyuktiryaki B,
|
||
Giovannini M,
|
||
Jayasinghe S,
|
||
Jaumdally H,
|
||
Marques-Mejias A,
|
||
Piletta-Zanin A,
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||
Berbenyuk A,
|
||
Andreeva M,
|
||
Levina D,
|
||
Iakovleva E,
|
||
Roberts G,
|
||
Chu D,
|
||
Peters R,
|
||
du Toit G,
|
||
Skypala I,
|
||
Santos AF</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2024 Feb;79(2):324-352.
|
||
Epub 2023 Nov 27
|
||
doi: 10.1111/all.15939.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38009299" target="_blank">38009299</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36529441">Omalizumab in IgE-Mediated Food Allergy: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zuberbier T,
|
||
Wood RA,
|
||
Bindslev-Jensen C,
|
||
Fiocchi A,
|
||
Chinthrajah RS,
|
||
Worm M,
|
||
Deschildre A,
|
||
Fernandez-Rivas M,
|
||
Santos AF,
|
||
Jaumont X,
|
||
Tassinari P</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol Pract</span>
|
||
2023 Apr;11(4):1134-1146.
|
||
Epub 2022 Dec 15
|
||
doi: 10.1016/j.jaip.2022.11.036.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36529441" target="_blank">36529441</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36271775">Frequency of food allergy in Europe: An updated systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Spolidoro GCI,
|
||
Amera YT,
|
||
Ali MM,
|
||
Nyassi S,
|
||
Lisik D,
|
||
Ioannidou A,
|
||
Rovner G,
|
||
Khaleva E,
|
||
Venter C,
|
||
van Ree R,
|
||
Worm M,
|
||
Vlieg-Boerstra B,
|
||
Sheikh A,
|
||
Muraro A,
|
||
Roberts G,
|
||
Nwaru BI</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2023 Feb;78(2):351-368.
|
||
Epub 2022 Nov 7
|
||
doi: 10.1111/all.15560.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36271775" target="_blank">36271775</a><a href="/pmc/articles/PMC10099188" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32396244">Preventing food allergy in infancy and childhood: Systematic review of randomised controlled trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Silva D,
|
||
Halken S,
|
||
Singh C,
|
||
Muraro A,
|
||
Angier E,
|
||
Arasi S,
|
||
Arshad H,
|
||
Beyer K,
|
||
Boyle R,
|
||
du Toit G,
|
||
Eigenmann P,
|
||
Grimshaw K,
|
||
Hoest A,
|
||
Jones C,
|
||
Khaleva E,
|
||
Lack G,
|
||
Szajewska H,
|
||
Venter C,
|
||
Verhasselt V,
|
||
Roberts G;
|
||
European Academy of Allergy, Clinical Immunology Food Allergy, Anaphylaxis Guidelines Group</span><br />
|
||
<span class="medgenPMjournal">Pediatr Allergy Immunol</span>
|
||
2020 Oct;31(7):813-826.
|
||
Epub 2020 Jun 18
|
||
doi: 10.1111/pai.13273.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32396244" target="_blank">32396244</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28058751">Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nurmatov U,
|
||
Dhami S,
|
||
Arasi S,
|
||
Pajno GB,
|
||
Fernandez-Rivas M,
|
||
Muraro A,
|
||
Roberts G,
|
||
Akdis C,
|
||
Alvaro-Lozano M,
|
||
Beyer K,
|
||
Bindslev-Jensen C,
|
||
Burks W,
|
||
du Toit G,
|
||
Ebisawa M,
|
||
Eigenmann P,
|
||
Knol E,
|
||
Makela M,
|
||
Nadeau KC,
|
||
O'Mahony L,
|
||
Papadopoulos N,
|
||
Poulsen LK,
|
||
Sackesen C,
|
||
Sampson H,
|
||
Santos AF,
|
||
van Ree R,
|
||
Timmermans F,
|
||
Sheikh A</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2017 Aug;72(8):1133-1147.
|
||
Epub 2017 May 11
|
||
doi: 10.1111/all.13124.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28058751" target="_blank">28058751</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20allergy%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (212)</a></div></div>
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