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<!--
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UID=124363
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ConceptID=C0270715
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Degenerative disease of the central nervous system</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>124363</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0270715</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Degenerative Diseases, Central Nervous System</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
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<td>Degenerative disease of the central nervous system (80690008)</td></tr>
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<div class="portlet_content ln">A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Degenerative disease of the central nervous system</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/311052" ref="tree=MeSH" title="MedGen record for Non-Neoplastic Disorder">Non-Neoplastic Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/317955" ref="tree=MeSH" title="MedGen record for Non-Neoplastic Disorder by Special Category">Non-Neoplastic Disorder by Special Category</a></span><ul><li><span class="TLline"><a href="/medgen/224837" ref="tree=MeSH" title="MedGen record for Degenerative disorder">Degenerative disorder</a></span><ul><li><span class="matched_ds">Degenerative disease of the central nervous system</span><ul><li><span class="TLline"><a href="/medgen/274" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis">Amyotrophic lateral sclerosis</a></span><ul><li><span class="TLline"><a href="/medgen/462753" ref="tree=MeSH" title="MedGen record for Amyotrophic Lateral Sclerosis 14, With or Without Frontotemporal Dementia">Amyotrophic Lateral Sclerosis 14, With or Without Frontotemporal Dementia</a></span></li><li><span class="TLline"><a href="/medgen/400169" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 1">Amyotrophic lateral sclerosis type 1</a></span></li><li><span class="TLline"><a href="/medgen/339829" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 3">Amyotrophic lateral sclerosis type 3</a></span></li><li><span class="TLline"><a href="/medgen/355983" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 4">Amyotrophic lateral sclerosis type 4</a></span></li><li><span class="TLline"><a href="/medgen/419901" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 6">Amyotrophic lateral sclerosis type 6</a></span><ul><li><span class="TLline"><a href="/medgen/413027" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis 6, autosomal recessive">Amyotrophic lateral sclerosis 6, autosomal recessive</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/334136" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 7">Amyotrophic lateral sclerosis type 7</a></span></li><li><span class="TLline"><a href="/medgen/325237" 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23">Amyotrophic lateral sclerosis type 23</a></span></li><li><span class="TLline"><a href="/medgen/923704" ref="tree=MeSH" title="MedGen record for Juvenile amyotrophic lateral sclerosis">Juvenile amyotrophic lateral sclerosis</a></span><ul><li><span class="TLline"><a href="/medgen/356388" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 5">Amyotrophic lateral sclerosis type 5</a></span></li><li><span class="TLline"><a href="/medgen/482217" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 16">Amyotrophic lateral sclerosis type 16</a></span></li><li><span class="TLline"><a href="/medgen/349246" ref="tree=MeSH" title="MedGen record for Amyotrophic lateral sclerosis type 2, juvenile">Amyotrophic lateral sclerosis type 2, juvenile</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/214634" ref="tree=MeSH" title="MedGen record for Progressive muscular atrophy">Progressive muscular atrophy</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1617621" ref="tree=MeSH" title="MedGen record for Brachial amyotrophic diplegia">Brachial amyotrophic diplegia</a></span></li><li><span class="TLline"><a href="/medgen/854" ref="tree=MeSH" title="MedGen record for Cerebral palsy">Cerebral palsy</a></span><ul><li><span class="TLline"><a href="/medgen/95998" ref="tree=MeSH" title="MedGen record for Ataxic cerebral palsy">Ataxic cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/82853" ref="tree=MeSH" title="MedGen record for Athetoid cerebral palsy">Athetoid cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/98296" ref="tree=MeSH" title="MedGen record for Hypotonic cerebral palsy">Hypotonic cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/148218" ref="tree=MeSH" title="MedGen record for Mixed cerebral palsy">Mixed cerebral palsy</a></span></li><li><span class="TLline"><a href="/medgen/137905" ref="tree=MeSH" title="MedGen record for Spastic 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Alzheimer disease 2">Alzheimer disease 2</a></span></li><li><span class="TLline"><a href="/medgen/334304" ref="tree=MeSH" title="MedGen record for Alzheimer disease 3">Alzheimer disease 3</a></span></li><li><span class="TLline"><a href="/medgen/376072" ref="tree=MeSH" title="MedGen record for Alzheimer disease 4">Alzheimer disease 4</a></span></li><li><span class="TLline"><a href="/medgen/381362" ref="tree=MeSH" title="MedGen record for Alzheimer disease 6">Alzheimer disease 6</a></span></li><li><span class="TLline"><a href="/medgen/342907" ref="tree=MeSH" title="MedGen record for Alzheimer disease 7">Alzheimer disease 7</a></span></li><li><span class="TLline"><a href="/medgen/375956" ref="tree=MeSH" title="MedGen record for Alzheimer disease 8">Alzheimer disease 8</a></span></li><li><span class="TLline"><a href="/medgen/924255" ref="tree=MeSH" title="MedGen record for Alzheimer disease 9">Alzheimer disease 9</a></span></li><li><span class="TLline"><a href="/medgen/351228" ref="tree=MeSH" title="MedGen record for Alzheimer disease 10">Alzheimer disease 10</a></span></li><li><span class="TLline"><a href="/medgen/377886" ref="tree=MeSH" title="MedGen record for Alzheimer disease 11">Alzheimer disease 11</a></span></li><li><span class="TLline"><a href="/medgen/410013" ref="tree=MeSH" title="MedGen record for Alzheimer disease 12">Alzheimer disease 12</a></span></li><li><span class="TLline"><a href="/medgen/370835" ref="tree=MeSH" title="MedGen record for Alzheimer disease 13">Alzheimer disease 13</a></span></li><li><span class="TLline"><a href="/medgen/369666" ref="tree=MeSH" title="MedGen record for Alzheimer disease 14">Alzheimer disease 14</a></span></li><li><span class="TLline"><a href="/medgen/394384" ref="tree=MeSH" title="MedGen record for Alzheimer disease 16">Alzheimer disease 16</a></span></li><li><span class="TLline"><a href="/medgen/767366" ref="tree=MeSH" title="MedGen record for Alzheimer disease 17">Alzheimer disease 17</a></span></li><li><span class="TLline"><a href="/medgen/346983" ref="tree=MeSH" title="MedGen record for Alzheimer disease without neurofibrillary tangles">Alzheimer disease without neurofibrillary tangles</a></span></li><li><span class="TLline"><a href="/medgen/448010" ref="tree=MeSH" title="MedGen record for Early-onset autosomal dominant Alzheimer disease">Early-onset autosomal dominant Alzheimer disease</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/7179" ref="tree=MeSH" title="MedGen record for Creutzfeldt-Jakob disease">Creutzfeldt-Jakob disease</a></span><ul><li><span class="TLline"><a href="/medgen/1826177" ref="tree=MeSH" title="MedGen record for Acquired Creutzfeldt-Jakob disease">Acquired Creutzfeldt-Jakob disease</a></span></li><li><span class="TLline"><a href="/medgen/155837" ref="tree=MeSH" title="MedGen record for Inherited Creutzfeldt-Jakob disease">Inherited Creutzfeldt-Jakob disease</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/148228" ref="tree=MeSH" title="MedGen record for Degenerations, Frontotemporal Lobar">Degenerations, Frontotemporal Lobar</a></span><ul><li><span class="TLline"><a href="/medgen/83266" ref="tree=MeSH" title="MedGen record for Frontotemporal dementia">Frontotemporal dementia</a></span></li><li><span class="TLline"><a href="/medgen/148373" ref="tree=MeSH" title="MedGen record for Primary progressive non fluent aphasia">Primary progressive non fluent aphasia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/177" ref="tree=MeSH" title="MedGen record for Dementia associated with AIDS">Dementia associated with AIDS</a></span></li><li><span class="TLline"><a href="/medgen/403960" ref="tree=MeSH" title="MedGen record for Diffuse Neurofibrillary Tangles with Calcification">Diffuse Neurofibrillary Tangles with Calcification</a></span></li><li><span class="TLline"><a href="/medgen/572577" ref="tree=MeSH" title="MedGen record for Frontal lobe dementia">Frontal lobe dementia</a></span></li><li><span class="TLline"><a href="/medgen/324447" ref="tree=MeSH" title="MedGen record for Frontolimbic dementia">Frontolimbic dementia</a></span></li><li><span class="TLline"><a href="/medgen/5654" ref="tree=MeSH" title="MedGen record for Huntington disease">Huntington disease</a></span><ul><li><span class="TLline"><a href="/medgen/155518" ref="tree=MeSH" title="MedGen record for Juvenile Huntington disease">Juvenile Huntington disease</a></span></li><li><span class="TLline"><a href="/medgen/224821" ref="tree=MeSH" title="MedGen record for Westphal disease">Westphal disease</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124361" ref="tree=MeSH" title="MedGen record for Kluver-Bucy syndrome">Kluver-Bucy syndrome</a></span></li><li><span class="TLline"><a href="/medgen/199874" ref="tree=MeSH" title="MedGen record for Lewy body dementia">Lewy body dementia</a></span></li><li><span class="TLline"><a href="/medgen/8278" ref="tree=MeSH" title="MedGen record for Presenile dementia">Presenile dementia</a></span></li><li><span class="TLline"><a href="/medgen/79466" ref="tree=MeSH" title="MedGen record for Primary progressive aphasia">Primary progressive aphasia</a></span><ul><li><span class="TLline"><a href="/medgen/907332" ref="tree=MeSH" title="MedGen record for Logopenic progressive aphasia">Logopenic progressive aphasia</a></span></li><li><span class="TLline"><a href="/medgen/83268" ref="tree=MeSH" title="MedGen record for Semantic dementia">Semantic dementia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/8279" ref="tree=MeSH" title="MedGen record for Senile dementia">Senile dementia</a></span></li><li><span class="TLline"><a href="/medgen/870488" ref="tree=MeSH" title="MedGen record for Subcortical dementia">Subcortical dementia</a></span></li><li><span class="TLline"><a href="/medgen/41447" ref="tree=MeSH" title="MedGen record for Vascular dementia">Vascular dementia</a></span><ul><li><span class="TLline"><a href="/medgen/199687" ref="tree=MeSH" title="MedGen record for Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy">Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy</a></span></li><li><span class="TLline"><a href="/medgen/8277" ref="tree=MeSH" title="MedGen record for Multi-infarct dementia">Multi-infarct dementia</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/3719" ref="tree=MeSH" title="MedGen record for Demyelinating disease of central nervous system">Demyelinating disease of central nervous system</a></span><ul><li><span class="TLline"><a href="/medgen/272540" ref="tree=MeSH" title="MedGen record for Demyelinating Encephalopathy">Demyelinating Encephalopathy</a></span><ul><li><span class="TLline"><a href="/medgen/64511" ref="tree=MeSH" title="MedGen record for Central pontine myelinolysis">Central pontine myelinolysis</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/155630" ref="tree=MeSH" title="MedGen record for Dentatorubral-pallidoluysian atrophy">Dentatorubral-pallidoluysian atrophy</a></span></li><li><span class="TLline"><a href="/medgen/41927" ref="tree=MeSH" title="MedGen record for Extrapyramidal disease">Extrapyramidal disease</a></span><ul><li><span class="TLline"><a href="/medgen/10590" ref="tree=MeSH" title="MedGen record for Parkinson disease">Parkinson disease</a></span><ul><li><span class="TLline"><a href="/medgen/357008" ref="tree=MeSH" title="MedGen record for Autosomal dominant Parkinson disease 1">Autosomal dominant Parkinson disease 1</a></span></li><li><span class="TLline"><a href="/medgen/381361" ref="tree=MeSH" title="MedGen record for Autosomal dominant Parkinson disease 4">Autosomal dominant Parkinson disease 4</a></span></li><li><span class="TLline"><a href="/medgen/339628" ref="tree=MeSH" title="MedGen record for Autosomal dominant Parkinson disease 8">Autosomal dominant Parkinson disease 8</a></span></li><li><span class="TLline"><a href="/medgen/342982" ref="tree=MeSH" title="MedGen record for Autosomal recessive early-onset Parkinson disease 6">Autosomal recessive early-onset Parkinson disease 6</a></span></li><li><span class="TLline"><a href="/medgen/344049" ref="tree=MeSH" title="MedGen record for Autosomal recessive early-onset Parkinson disease 7">Autosomal recessive early-onset Parkinson disease 7</a></span></li><li><span class="TLline"><a href="/medgen/401500" ref="tree=MeSH" title="MedGen record for Autosomal recessive juvenile Parkinson disease 2">Autosomal recessive juvenile Parkinson disease 2</a></span></li><li><span class="TLline"><a href="/medgen/414488" ref="tree=MeSH" title="MedGen record for Autosomal recessive Parkinson disease 14">Autosomal recessive Parkinson disease 14</a></span></li><li><span class="TLline"><a href="/medgen/66768" ref="tree=MeSH" title="MedGen record for Juvenile paralysis agitans of Hunt">Juvenile paralysis agitans of Hunt</a></span></li><li><span class="TLline"><a href="/medgen/338281" ref="tree=MeSH" title="MedGen record for Kufor-Rakeb syndrome">Kufor-Rakeb syndrome</a></span></li><li><span class="TLline"><a href="/medgen/409973" ref="tree=MeSH" title="MedGen record for Parkinson disease 6">Parkinson disease 6</a></span></li><li><span class="TLline"><a href="/medgen/339741" ref="tree=MeSH" title="MedGen record for Parkinson disease 10">Parkinson disease 10</a></span></li><li><span class="TLline"><a href="/medgen/896658" ref="tree=MeSH" title="MedGen record for Parkinson disease 11, autosomal dominant, susceptibility to">Parkinson disease 11, autosomal dominant, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/337173" ref="tree=MeSH" title="MedGen record for Parkinson disease 12">Parkinson disease 12</a></span></li><li><span class="TLline"><a href="/medgen/343992" ref="tree=MeSH" title="MedGen record for Parkinson disease 13, autosomal dominant, susceptibility to">Parkinson disease 13, autosomal dominant, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/442620" ref="tree=MeSH" title="MedGen record for Parkinson disease 16">Parkinson disease 16</a></span></li><li><span class="TLline"><a href="/medgen/481763" ref="tree=MeSH" title="MedGen record for Parkinson disease 17">Parkinson disease 17</a></span></li><li><span class="TLline"><a href="/medgen/355499" ref="tree=MeSH" title="MedGen record for Parkinson disease 3, autosomal dominant">Parkinson disease 3, autosomal dominant</a></span></li><li><span class="TLline"><a href="/medgen/462249" ref="tree=MeSH" title="MedGen record for Parkinson disease 5, autosomal dominant, susceptibility to">Parkinson disease 5, autosomal dominant, susceptibility to</a></span></li><li><span class="TLline"><a href="/medgen/463618" ref="tree=MeSH" title="MedGen record for Parkinson disease, late-onset">Parkinson disease, late-onset</a></span></li><li><span class="TLline"><a href="/medgen/333199" ref="tree=MeSH" title="MedGen record for Parkinson disease, mitochondrial">Parkinson disease, mitochondrial</a></span></li><li><span class="TLline"><a href="/medgen/337969" ref="tree=MeSH" title="MedGen record for Parkinsonian-pyramidal syndrome">Parkinsonian-pyramidal syndrome</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/854771" ref="tree=MeSH" title="MedGen record for Frontotemporal dementia with motor neuron disease">Frontotemporal dementia with motor neuron disease</a></span></li><li><span class="TLline"><a href="/medgen/474858" ref="tree=MeSH" title="MedGen record for Hereditary Neurodegenerative Disorder">Hereditary Neurodegenerative Disorder</a></span><ul><li><span class="TLline"><a href="/medgen/482001" ref="tree=MeSH" title="MedGen record for Neurodegeneration with brain iron accumulation 4">Neurodegeneration with brain iron accumulation 4</a></span></li><li><span class="TLline"><a href="/medgen/763887" ref="tree=MeSH" title="MedGen record for Neurodegeneration with brain iron accumulation 5">Neurodegeneration with brain iron accumulation 5</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/20844" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia">Hereditary spastic paraplegia</a></span><ul><li><span class="TLline"><a href="/medgen/934734" ref="tree=MeSH" title="MedGen record for Cerebral palsy, spastic quadriplegic, 3">Cerebral palsy, spastic quadriplegic, 3</a></span></li><li><span class="TLline"><a href="/medgen/339552" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 7">Hereditary spastic paraplegia 7</a></span></li><li><span class="TLline"><a href="/medgen/388073" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 11">Hereditary spastic paraplegia 11</a></span></li><li><span class="TLline"><a href="/medgen/419393" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 3A">Hereditary spastic paraplegia 3A</a></span></li><li><span class="TLline"><a href="/medgen/481368" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 47">Hereditary spastic paraplegia 47</a></span></li><li><span class="TLline"><a href="/medgen/376521" ref="tree=MeSH" title="MedGen record for Hereditary spastic paraplegia 5A">Hereditary spastic paraplegia 5A</a></span></li><li><span class="TLline"><a href="/medgen/777979" ref="tree=MeSH" title="MedGen record for Spastic Paraplegia 4">Spastic Paraplegia 4</a></span></li><li><span class="TLline"><a href="/medgen/1678550" ref="tree=MeSH" title="MedGen record for Spastic Paraplegia 76">Spastic Paraplegia 76</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/61440" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease">Pelizaeus-Merzbacher disease</a></span><ul><li><span class="TLline"><a href="/medgen/1740046" ref="tree=MeSH" title="MedGen record for Null syndrome">Null syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1753109" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease in female carriers">Pelizaeus-Merzbacher disease in female carriers</a></span></li><li><span class="TLline"><a href="/medgen/155959" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, classic form">Pelizaeus-Merzbacher disease, classic form</a></span></li><li><span class="TLline"><a href="/medgen/1842817" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, connatal form">Pelizaeus-Merzbacher disease, connatal form</a></span></li><li><span class="TLline"><a href="/medgen/199764" ref="tree=MeSH" title="MedGen record for Pelizaeus-Merzbacher disease, transitional form">Pelizaeus-Merzbacher disease, transitional form</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/116020" ref="tree=MeSH" title="MedGen record for Pick disease">Pick disease</a></span></li><li><span class="TLline"><a href="/medgen/6708" ref="tree=MeSH" title="MedGen record for Pigmentary pallidal degeneration">Pigmentary pallidal degeneration</a></span><ul><li><span class="TLline"><a href="/medgen/1800044" ref="tree=MeSH" title="MedGen record for Atypical pantothenate kinase-associated neurodegeneration">Atypical pantothenate kinase-associated neurodegeneration</a></span></li><li><span class="TLline"><a href="/medgen/1826057" ref="tree=MeSH" title="MedGen record for Classic pantothenate kinase-associated neurodegeneration">Classic pantothenate kinase-associated neurodegeneration</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/21026" ref="tree=MeSH" title="MedGen record for Progressive supranuclear palsy">Progressive supranuclear palsy</a></span><ul><li><span class="TLline"><a href="/medgen/1779597" ref="tree=MeSH" title="MedGen record for Atypical progressive supranuclear palsy syndrome">Atypical progressive supranuclear palsy syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1640811" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 1">Supranuclear palsy, progressive, 1</a></span></li><li><span class="TLline"><a href="/medgen/324446" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 2">Supranuclear palsy, progressive, 2</a></span></li><li><span class="TLline"><a href="/medgen/370922" ref="tree=MeSH" title="MedGen record for Supranuclear palsy, progressive, 3">Supranuclear palsy, progressive, 3</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/39733" ref="tree=MeSH" title="MedGen record for Spinocerebellar atrophy">Spinocerebellar atrophy</a></span><ul><li><span class="TLline"><a href="/medgen/767604" ref="tree=MeSH" title="MedGen record for Ataxia with oculomotor apraxia type 3">Ataxia with oculomotor apraxia type 3</a></span></li><li><span class="TLline"><a href="/medgen/395301" ref="tree=MeSH" title="MedGen record for Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia">Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia</a></span></li><li><span class="TLline"><a href="/medgen/439" ref="tree=MeSH" title="MedGen record for Ataxia-telangiectasia syndrome">Ataxia-telangiectasia syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1684639" ref="tree=MeSH" title="MedGen record for Autosomal dominant cerebellar ataxia">Autosomal dominant cerebellar ataxia</a></span></li><li><span class="TLline"><a href="/medgen/1843058" ref="tree=MeSH" title="MedGen record for Autosomal recessive cerebellar ataxia">Autosomal recessive cerebellar ataxia</a></span><ul><li><span class="TLline"><a href="/medgen/436985" ref="tree=MeSH" title="MedGen record for Autosomal recessive ataxia due to ubiquinone deficiency">Autosomal recessive ataxia due to ubiquinone deficiency</a></span></li><li><span class="TLline"><a href="/medgen/343973" ref="tree=MeSH" title="MedGen record for Autosomal recessive ataxia, Beauce type">Autosomal recessive ataxia, Beauce type</a></span></li><li><span class="TLline"><a href="/medgen/324520" ref="tree=MeSH" title="MedGen record for Autosomal recessive spinocerebellar ataxia 7">Autosomal recessive spinocerebellar ataxia 7</a></span></li><li><span class="TLline"><a href="/medgen/462348" ref="tree=MeSH" title="MedGen record for Autosomal recessive spinocerebellar ataxia 10">Autosomal recessive spinocerebellar ataxia 10</a></span></li><li><span class="TLline"><a href="/medgen/1636182" ref="tree=MeSH" title="MedGen record for Autosomal recessive spinocerebellar ataxia 14">Autosomal recessive spinocerebellar ataxia 14</a></span></li><li><span class="TLline"><a href="/medgen/1674542" ref="tree=MeSH" title="MedGen record for Autosomal recessive spinocerebellar ataxia 16">Autosomal recessive spinocerebellar ataxia 16</a></span></li><li><span class="TLline"><a href="/medgen/334220" ref="tree=MeSH" title="MedGen record for Infantile-onset autosomal recessive nonprogressive cerebellar ataxia">Infantile-onset autosomal recessive nonprogressive cerebellar ataxia</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/9841" ref="tree=MeSH" title="MedGen record for Azorean disease">Azorean disease</a></span><ul><li><span class="TLline"><a href="/medgen/155610" ref="tree=MeSH" title="MedGen record for Machado-Joseph disease type 1">Machado-Joseph disease type 1</a></span></li><li><span class="TLline"><a href="/medgen/199707" ref="tree=MeSH" title="MedGen record for Machado-Joseph disease type 2">Machado-Joseph disease type 2</a></span></li><li><span class="TLline"><a href="/medgen/155611" ref="tree=MeSH" title="MedGen record for Machado-Joseph disease type 3">Machado-Joseph disease type 3</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/341248" ref="tree=MeSH" title="MedGen record for Familial isolated deficiency of vitamin E">Familial isolated deficiency of vitamin E</a></span></li><li><span class="TLline"><a href="/medgen/156006" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia 7">Spinocerebellar ataxia 7</a></span></li><li><span class="TLline"><a href="/medgen/155703" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 1">Spinocerebellar ataxia type 1</a></span></li><li><span class="TLline"><a href="/medgen/155704" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 2">Spinocerebellar ataxia type 2</a></span></li><li><span class="TLline"><a href="/medgen/148458" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 6">Spinocerebellar ataxia type 6</a></span></li><li><span class="TLline"><a href="/medgen/347653" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 12">Spinocerebellar ataxia type 12</a></span></li><li><span class="TLline"><a href="/medgen/337637" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 17">Spinocerebellar ataxia type 17</a></span></li><li><span class="TLline"><a href="/medgen/1711119" ref="tree=MeSH" title="MedGen record for Spinocerebellar Ataxia Type 19/22">Spinocerebellar Ataxia Type 19/22</a></span></li><li><span class="TLline"><a href="/medgen/348439" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 31">Spinocerebellar ataxia type 31</a></span></li><li><span class="TLline"><a href="/medgen/483339" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 36">Spinocerebellar ataxia type 36</a></span></li><li><span class="TLline"><a href="/medgen/902592" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia type 42">Spinocerebellar ataxia type 42</a></span></li><li><span class="TLline"><a href="/medgen/340052" ref="tree=MeSH" title="MedGen record for Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2">Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124366" ref="tree=MeSH" title="MedGen record for Striatonigral degeneration">Striatonigral degeneration</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/38654507">Ginkgo biloba and Its Chemical Components in the Management of Alzheimer's Disease.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Peng Y,
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Chen Q,
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Xue YH,
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Jin H,
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Liu S,
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Du MQ,
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Yao SY</span><br />
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<span class="medgenPMjournal">Am J Chin Med</span>
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2024;52(3):625-666.
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Epub 2024 Apr 24
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doi: 10.1142/S0192415X24500277.
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<span class="bold">PMID: </span><a href="/pubmed/38654507" target="_blank">38654507</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37741528">Multiple sclerosis and pregnancy: Pathogenesis, influencing factors, and treatment options.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
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Wang J,
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Feng J</span><br />
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<span class="medgenPMjournal">Autoimmun Rev</span>
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2023 Nov;22(11):103449.
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Epub 2023 Sep 21
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doi: 10.1016/j.autrev.2023.103449.
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<span class="bold">PMID: </span><a href="/pubmed/37741528" target="_blank">37741528</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37114956">Current study on diagnosis and treatment of Alzheimer's disease by targeting amyloid b-protein.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hua KY,
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Zhao WJ</span><br />
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<span class="medgenPMjournal">Folia Neuropathol</span>
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2023;61(1):8-15.
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doi: 10.5114/fn.2022.119778.
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<span class="bold">PMID: </span><a href="/pubmed/37114956" target="_blank">37114956</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22degenerative%20disease%20of%20the%20central%20nervous%20system%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (13)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37997324">Cognitive-motor dual-task training improves dynamic stability during straight and curved gait in patients with multiple sclerosis: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tramontano M,
|
||
Argento O,
|
||
Orejel Bustos AS,
|
||
DE Angelis S,
|
||
Montemurro R,
|
||
Bossa M,
|
||
Belluscio V,
|
||
Bergamini E,
|
||
Vannozzi G,
|
||
Nocentini U</span><br />
|
||
<span class="medgenPMjournal">Eur J Phys Rehabil Med</span>
|
||
2024 Feb;60(1):27-36.
|
||
Epub 2023 Nov 23
|
||
doi: 10.23736/S1973-9087.23.08156-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37997324" target="_blank">37997324</a><a href="/pmc/articles/PMC10932486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37001498">Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Charabati M,
|
||
Wheeler MA,
|
||
Weiner HL,
|
||
Quintana FJ</span><br />
|
||
<span class="medgenPMjournal">Cell</span>
|
||
2023 Mar 30;186(7):1309-1327.
|
||
doi: 10.1016/j.cell.2023.03.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37001498" target="_blank">37001498</a><a href="/pmc/articles/PMC10119687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34758102">Correlation between head tremble and the severity of Parkinson's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang J,
|
||
Guo Q,
|
||
Zou X,
|
||
Wang M,
|
||
Wen Y,
|
||
Chen X,
|
||
Weng X,
|
||
Xu F</span><br />
|
||
<span class="medgenPMjournal">CNS Neurosci Ther</span>
|
||
2022 Feb;28(2):218-225.
|
||
Epub 2021 Nov 10
|
||
doi: 10.1111/cns.13753.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34758102" target="_blank">34758102</a><a href="/pmc/articles/PMC8739048" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33893981">The relationship between diabetes-related cognitive dysfunction and leukoaraiosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan CL,
|
||
Yi R,
|
||
Dong Q,
|
||
Yao LF,
|
||
Liu B</span><br />
|
||
<span class="medgenPMjournal">Acta Neurol Belg</span>
|
||
2021 Oct;121(5):1101-1110.
|
||
Epub 2021 Apr 24
|
||
doi: 10.1007/s13760-021-01676-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33893981" target="_blank">33893981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/13626997">Kuru; clinical, pathological and epidemiological study of an acute progressive degenerative disease of the central nervous system among natives of the Eastern Highlands of New Guinea.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">GAJDUSEK DC,
|
||
ZIGAS V</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
1959 Mar;26(3):442-69.
|
||
doi: 10.1016/0002-9343(59)90251-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/13626997" target="_blank">13626997</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (53)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37114956">Current study on diagnosis and treatment of Alzheimer's disease by targeting amyloid b-protein.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hua KY,
|
||
Zhao WJ</span><br />
|
||
<span class="medgenPMjournal">Folia Neuropathol</span>
|
||
2023;61(1):8-15.
|
||
doi: 10.5114/fn.2022.119778.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37114956" target="_blank">37114956</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34758102">Correlation between head tremble and the severity of Parkinson's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yang J,
|
||
Guo Q,
|
||
Zou X,
|
||
Wang M,
|
||
Wen Y,
|
||
Chen X,
|
||
Weng X,
|
||
Xu F</span><br />
|
||
<span class="medgenPMjournal">CNS Neurosci Ther</span>
|
||
2022 Feb;28(2):218-225.
|
||
Epub 2021 Nov 10
|
||
doi: 10.1111/cns.13753.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34758102" target="_blank">34758102</a><a href="/pmc/articles/PMC8739048" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33893981">The relationship between diabetes-related cognitive dysfunction and leukoaraiosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan CL,
|
||
Yi R,
|
||
Dong Q,
|
||
Yao LF,
|
||
Liu B</span><br />
|
||
<span class="medgenPMjournal">Acta Neurol Belg</span>
|
||
2021 Oct;121(5):1101-1110.
|
||
Epub 2021 Apr 24
|
||
doi: 10.1007/s13760-021-01676-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33893981" target="_blank">33893981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4554083">Investigation of degenerative disease of the central nervous system.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson J</span><br />
|
||
<span class="medgenPMjournal">Arch Dis Child</span>
|
||
1972 Apr;47(252):163-70.
|
||
doi: 10.1136/adc.47.252.163.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4554083" target="_blank">4554083</a><a href="/pmc/articles/PMC1648073" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4242467">Degenerative disease of the central nervous system.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Freeman JM,
|
||
McKhann GM</span><br />
|
||
<span class="medgenPMjournal">Adv Pediatr</span>
|
||
1969;16:121-75.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4242467" target="_blank">4242467</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (37)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38654507">Ginkgo biloba and Its Chemical Components in the Management of Alzheimer's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Peng Y,
|
||
Chen Q,
|
||
Xue YH,
|
||
Jin H,
|
||
Liu S,
|
||
Du MQ,
|
||
Yao SY</span><br />
|
||
<span class="medgenPMjournal">Am J Chin Med</span>
|
||
2024;52(3):625-666.
|
||
Epub 2024 Apr 24
|
||
doi: 10.1142/S0192415X24500277.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38654507" target="_blank">38654507</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38611758">Neuroinflammation of Microglial Regulation in Alzheimer's Disease: Therapeutic Approaches.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen H,
|
||
Zeng Y,
|
||
Wang D,
|
||
Li Y,
|
||
Xing J,
|
||
Zeng Y,
|
||
Liu Z,
|
||
Zhou X,
|
||
Fan H</span><br />
|
||
<span class="medgenPMjournal">Molecules</span>
|
||
2024 Mar 26;29(7)
|
||
doi: 10.3390/molecules29071478.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38611758" target="_blank">38611758</a><a href="/pmc/articles/PMC11013124" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37997324">Cognitive-motor dual-task training improves dynamic stability during straight and curved gait in patients with multiple sclerosis: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tramontano M,
|
||
Argento O,
|
||
Orejel Bustos AS,
|
||
DE Angelis S,
|
||
Montemurro R,
|
||
Bossa M,
|
||
Belluscio V,
|
||
Bergamini E,
|
||
Vannozzi G,
|
||
Nocentini U</span><br />
|
||
<span class="medgenPMjournal">Eur J Phys Rehabil Med</span>
|
||
2024 Feb;60(1):27-36.
|
||
Epub 2023 Nov 23
|
||
doi: 10.23736/S1973-9087.23.08156-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37997324" target="_blank">37997324</a><a href="/pmc/articles/PMC10932486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37114956">Current study on diagnosis and treatment of Alzheimer's disease by targeting amyloid b-protein.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hua KY,
|
||
Zhao WJ</span><br />
|
||
<span class="medgenPMjournal">Folia Neuropathol</span>
|
||
2023;61(1):8-15.
|
||
doi: 10.5114/fn.2022.119778.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37114956" target="_blank">37114956</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36472107">Research Progress of Targeting Neuro-Immune Inflammation in the Treatment of Alzheimer's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen H,
|
||
Deng C,
|
||
Meng Z,
|
||
Meng S</span><br />
|
||
<span class="medgenPMjournal">Front Biosci (Landmark Ed)</span>
|
||
2022 Nov 25;27(11):312.
|
||
doi: 10.31083/j.fbl2711312.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36472107" target="_blank">36472107</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (35)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37741528">Multiple sclerosis and pregnancy: Pathogenesis, influencing factors, and treatment options.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
|
||
Wang J,
|
||
Feng J</span><br />
|
||
<span class="medgenPMjournal">Autoimmun Rev</span>
|
||
2023 Nov;22(11):103449.
|
||
Epub 2023 Sep 21
|
||
doi: 10.1016/j.autrev.2023.103449.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37741528" target="_blank">37741528</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37114956">Current study on diagnosis and treatment of Alzheimer's disease by targeting amyloid b-protein.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hua KY,
|
||
Zhao WJ</span><br />
|
||
<span class="medgenPMjournal">Folia Neuropathol</span>
|
||
2023;61(1):8-15.
|
||
doi: 10.5114/fn.2022.119778.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37114956" target="_blank">37114956</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33893981">The relationship between diabetes-related cognitive dysfunction and leukoaraiosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan CL,
|
||
Yi R,
|
||
Dong Q,
|
||
Yao LF,
|
||
Liu B</span><br />
|
||
<span class="medgenPMjournal">Acta Neurol Belg</span>
|
||
2021 Oct;121(5):1101-1110.
|
||
Epub 2021 Apr 24
|
||
doi: 10.1007/s13760-021-01676-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33893981" target="_blank">33893981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30411550">Interactions between platelets and leukocytes in pathogenesis of multiple sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dziedzic A,
|
||
Bijak M</span><br />
|
||
<span class="medgenPMjournal">Adv Clin Exp Med</span>
|
||
2019 Feb;28(2):277-285.
|
||
doi: 10.17219/acem/83588.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30411550" target="_blank">30411550</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28391781">Multiple Sclerosis: Epidemiologic, Clinical, and Therapeutic Aspects.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vidal-Jordana A,
|
||
Montalban X</span><br />
|
||
<span class="medgenPMjournal">Neuroimaging Clin N Am</span>
|
||
2017 May;27(2):195-204.
|
||
doi: 10.1016/j.nic.2016.12.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28391781" target="_blank">28391781</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (27)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37997324">Cognitive-motor dual-task training improves dynamic stability during straight and curved gait in patients with multiple sclerosis: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tramontano M,
|
||
Argento O,
|
||
Orejel Bustos AS,
|
||
DE Angelis S,
|
||
Montemurro R,
|
||
Bossa M,
|
||
Belluscio V,
|
||
Bergamini E,
|
||
Vannozzi G,
|
||
Nocentini U</span><br />
|
||
<span class="medgenPMjournal">Eur J Phys Rehabil Med</span>
|
||
2024 Feb;60(1):27-36.
|
||
Epub 2023 Nov 23
|
||
doi: 10.23736/S1973-9087.23.08156-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37997324" target="_blank">37997324</a><a href="/pmc/articles/PMC10932486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37507575">Reexamining the Causes and Effects of Cholesterol Deposition in the Brains of Patients with Alzheimer's Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hu ZL,
|
||
Yuan YQ,
|
||
Tong Z,
|
||
Liao MQ,
|
||
Yuan SL,
|
||
Jian Y,
|
||
Yang JL,
|
||
Liu WF</span><br />
|
||
<span class="medgenPMjournal">Mol Neurobiol</span>
|
||
2023 Dec;60(12):6852-6868.
|
||
Epub 2023 Jul 28
|
||
doi: 10.1007/s12035-023-03529-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37507575" target="_blank">37507575</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37176155">The Role of BDNF in Multiple Sclerosis Neuroinflammation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nociti V,
|
||
Romozzi M</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2023 May 8;24(9)
|
||
doi: 10.3390/ijms24098447.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37176155" target="_blank">37176155</a><a href="/pmc/articles/PMC10178984" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33893981">The relationship between diabetes-related cognitive dysfunction and leukoaraiosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yuan CL,
|
||
Yi R,
|
||
Dong Q,
|
||
Yao LF,
|
||
Liu B</span><br />
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<span class="medgenPMjournal">Acta Neurol Belg</span>
|
||
2021 Oct;121(5):1101-1110.
|
||
Epub 2021 Apr 24
|
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doi: 10.1007/s13760-021-01676-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33893981" target="_blank">33893981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29373838">Quantifying multiple sclerosis pathology in post mortem spinal cord using MRI.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Schmierer K,
|
||
McDowell A,
|
||
Petrova N,
|
||
Carassiti D,
|
||
Thomas DL,
|
||
Miquel ME</span><br />
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<span class="medgenPMjournal">Neuroimage</span>
|
||
2018 Nov 15;182:251-258.
|
||
Epub 2018 Jan 31
|
||
doi: 10.1016/j.neuroimage.2018.01.052.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29373838" target="_blank">29373838</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (34)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/39579647">Psychometric properties of patient-reported outcome measures, measuring fatigue in patients with multiple sclerosis, a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ruzzi MAJ,
|
||
Coll MB,
|
||
Mata MJD,
|
||
Tello MCR,
|
||
García IC</span><br />
|
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<span class="medgenPMjournal">Mult Scler Relat Disord</span>
|
||
2024 Dec;92:106169.
|
||
Epub 2024 Nov 14
|
||
doi: 10.1016/j.msard.2024.106169.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39579647" target="_blank">39579647</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37068369">The association between brain volume loss and disability in multiple sclerosis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Matthews PM,
|
||
Gupta D,
|
||
Mittal D,
|
||
Bai W,
|
||
Scalfari A,
|
||
Pollock KG,
|
||
Sharma V,
|
||
Hill N</span><br />
|
||
<span class="medgenPMjournal">Mult Scler Relat Disord</span>
|
||
2023 Jun;74:104714.
|
||
Epub 2023 Apr 9
|
||
doi: 10.1016/j.msard.2023.104714.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37068369" target="_blank">37068369</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36731808">Clinical efficacy and safety of compound Congrong Yizhi Capsules on Alzheimer's disease in mainland China: A systematic review with trial sequential analysis and GRADE assessment.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
|
||
Wang N,
|
||
Xu Z,
|
||
Liu S,
|
||
Liang X,
|
||
Zhang Y,
|
||
Jin X</span><br />
|
||
<span class="medgenPMjournal">J Ethnopharmacol</span>
|
||
2023 Jun 12;309:116208.
|
||
Epub 2023 Jan 31
|
||
doi: 10.1016/j.jep.2023.116208.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36731808" target="_blank">36731808</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35309325">A Systematic Review of Tissue and Single Cell Transcriptome/Proteome Studies of the Brain in Multiple Sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Elkjaer ML,
|
||
Röttger R,
|
||
Baumbach J,
|
||
Illes Z</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2022;13:761225.
|
||
Epub 2022 Mar 2
|
||
doi: 10.3389/fimmu.2022.761225.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35309325" target="_blank">35309325</a><a href="/pmc/articles/PMC8924618" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29313265">A Systematic Review of Discrete-Choice Experiments and Conjoint Analysis Studies in People with Multiple Sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Webb EJD,
|
||
Meads D,
|
||
Eskyte I,
|
||
King N,
|
||
Dracup N,
|
||
Chataway J,
|
||
Ford HL,
|
||
Marti J,
|
||
Pavitt SH,
|
||
Schmierer K,
|
||
Manzano A</span><br />
|
||
<span class="medgenPMjournal">Patient</span>
|
||
2018 Aug;11(4):391-402.
|
||
doi: 10.1007/s40271-017-0296-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29313265" target="_blank">29313265</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Degenerative%20disease%20of%20the%20central%20nervous%20system%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div></div>
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