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3045 lines
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244 KiB
XML
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'2825',linkname:'',idsfromresult:'966',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9d9b3d74f6769103ef7b6" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="2825" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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|
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
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</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
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<div>
|
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</div>
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<div class="">
|
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<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
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|
||
<div id="messagearea" class="empty">
|
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|
||
|
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|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">CD59</span> CD59 molecule (CD59 blood group) [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 966, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
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<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
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<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
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<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
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</h4>
|
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<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
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<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="CD59_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
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<input type="hidden" id="gene-id-value" value="966" />
|
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<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
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<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">CD59<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>CD59 molecule (CD59 blood group)<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1689" data-gblink-text="Ensembl">HGNC:HGNC:1689</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000085063" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000085063">Ensembl:ENSG00000085063</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/107271" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=966&link_uid=107271">MIM:107271;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:1689" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=966&link_uid=HGNC:1689">AllianceGenome:HGNC:1689</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=966&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Ubiquitous expression in gall bladder (RPKM 62.1), lung (RPKM 52.8) and 25 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="/gene/966/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/966/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/966/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See CD59 in </span><a href="/genome/gdv/?context=gene&acc=966" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">11p13</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>8</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=966&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_000011.10 (33703010..33736479, complement) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=966&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_060935.1 (33840023..33873492, complement) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=966&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_000011.9 (33724556..33758025, complement) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 11 - NC_000011.10</strong><img usemap="#nbrMap966_568815587" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=966&nuc_gi=568815587&n0=HIPK3&n1=LOC130005497&n2=LOC130005498&n3=LOC130005499&n4=LOC130005500&n5=LOC130005501&n6=LOC130005502&n7=LOC130005503&n8=KIAA1549L&n9=LOC130005504&n10=LOC130005505&n11=LOC130005506&n12=LOC130005507&n13=LOC130005508&n14=LOC130005509&n15=LOC130005510&n16=LOC127820719&n17=LOC127820720&n18=LOC105376617&n19=LOC126861178&n20=LOC130005511&n21=LOC126861179&n22=C11orf91&n23=LOC130005512&n24=LOC130005513&n25=CD59&n26=LOC130005514&n27=LOC130005515&n28=LOC130005516&n29=FBXO3&n30=LOC130005517&n31=LOC124421514&n32=LOC127820721&n33=LOC130005518&n34=FBXO3-DT" /><map name="nbrMap966_568815587" id="nbrMap966_568815587">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3232')" onMouseOut="hidetip()" coords="2,23,72,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3232" href="/gene/130005497" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3233')" onMouseOut="hidetip()" coords="3,35,73,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3233" href="/gene/130005498" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3234')" onMouseOut="hidetip()" coords="3,47,73,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3234" href="/gene/130005499" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4575')" onMouseOut="hidetip()" coords="3,59,73,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4575" href="/gene/130005500" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4576')" onMouseOut="hidetip()" coords="3,71,73,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4576" href="/gene/130005501" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'homeodomain interacting protein kinase 3')" onMouseOut="hidetip()" coords="37,83,133,91" alt="Neighboring gene homeodomain interacting protein kinase 3" href="/gene/10114" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3235')" onMouseOut="hidetip()" coords="85,23,155,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3235" href="/gene/130005502" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3236')" onMouseOut="hidetip()" coords="85,35,155,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3236" href="/gene/130005503" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3237')" onMouseOut="hidetip()" coords="85,47,155,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3237" href="/gene/130005504" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3238')" onMouseOut="hidetip()" coords="85,59,155,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3238" href="/gene/130005505" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'KIAA1549 like')" onMouseOut="hidetip()" coords="100,71,353,79" alt="Neighboring gene KIAA1549 like" href="/gene/25758" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4577')" onMouseOut="hidetip()" coords="109,95,179,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4577" href="/gene/130005506" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4578')" onMouseOut="hidetip()" coords="155,83,225,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4578" href="/gene/130005507" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4579')" onMouseOut="hidetip()" coords="181,23,251,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4579" href="/gene/130005508" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4580')" onMouseOut="hidetip()" coords="188,35,258,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4580" href="/gene/130005509" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4581')" onMouseOut="hidetip()" coords="255,23,325,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4581" href="/gene/130005510" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr11:33667485-33667984')" onMouseOut="hidetip()" coords="271,35,341,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:33667485-33667984" href="/gene/127820720" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr11:33666983-33667484')" onMouseOut="hidetip()" coords="271,47,341,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:33666983-33667484" href="/gene/127820719" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105376617')" onMouseOut="hidetip()" coords="277,59,351,67" alt="Neighboring gene uncharacterized LOC105376617" href="/gene/105376617" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'MED14-independent group 3 enhancer GRCh37_chr11:33676703-33677902')" onMouseOut="hidetip()" coords="278,83,348,91" alt="Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:33676703-33677902" href="/gene/126861178" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4582')" onMouseOut="hidetip()" coords="279,95,349,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4582" href="/gene/130005511" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:33711673-33712872')" onMouseOut="hidetip()" coords="302,107,372,115" alt="Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:33711673-33712872" href="/gene/126861179" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3239')" onMouseOut="hidetip()" coords="309,119,379,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3239" href="/gene/130005512" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3240')" onMouseOut="hidetip()" coords="309,131,379,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3240" href="/gene/130005513" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4583')" onMouseOut="hidetip()" coords="325,143,395,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4583" href="/gene/130005514" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'chromosome 11 open reading frame 91')" onMouseOut="hidetip()" coords="327,23,377,31" alt="Neighboring gene chromosome 11 open reading frame 91" href="/gene/100131378" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4584')" onMouseOut="hidetip()" coords="331,155,401,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4584" href="/gene/130005515" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3241')" onMouseOut="hidetip()" coords="334,167,404,175" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3241" href="/gene/130005516" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4585')" onMouseOut="hidetip()" coords="351,47,421,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4585" href="/gene/130005517" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12829')" onMouseOut="hidetip()" coords="353,59,423,67" alt="Neighboring gene Sharpr-MPRA regulatory region 12829" href="/gene/124421514" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr11:33795080-33795580')" onMouseOut="hidetip()" coords="353,83,423,91" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:33795080-33795580" href="/gene/127820721" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3243')" onMouseOut="hidetip()" coords="353,95,423,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3243" href="/gene/130005518" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'F-box protein 3')" onMouseOut="hidetip()" coords="372,71,422,79" alt="Neighboring gene F-box protein 3" href="/gene/26273" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'FBXO3 divergent transcript')" onMouseOut="hidetip()" coords="373,107,423,115" alt="Neighboring gene FBXO3 divergent transcript" href="/gene/101928440" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="966">
|
||
<option value="NC_000011.10_33703009_33736478">NC_000011.10 Chromosome 11 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NG_008057.1_4999_38468">NG_008057.1 RefSeqGene</option>
|
||
<option value="NC_060935.1_33840022_33873491">NC_060935.1 Chromosome 11 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000011.9_33724555_33758024">NC_000011.9 Chromosome 11 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000011" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000011.10?report=graph&from=33697989&to=33741498&strand=true&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000011.10?report=fasta&from=33703010&to=33736479&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000011.10?report=genbank&from=33703010&to=33736479&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000011" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000011.10&from=33697989&to=33741498&strand=true&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000011.10&from=33697989&to=33741498&strand=true&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000011.10" sid="1" type="hidden" id="nucleotideLink_NC_000011_10_33703009_33736478" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000011.10?report=graph&amp;from=33697989&amp;to=33741498&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.10">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000011.10?report=fasta&amp;from=33703010&amp;to=33736479&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.10">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000011.10?report=genbank&amp;from=33703010&amp;to=33736479&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.10">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000011.10" sid="1" type="hidden" id="relString_NC_000011_10_33703009_33736478" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000011.10&amp;from=33697989&amp;to=33741498&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_008057.1" sid="1" type="hidden" id="nucleotideLink_NG_008057_1_4999_38468" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_008057.1?report=graph&amp;from=1&amp;to=43488&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NG_008057.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_008057.1?report=fasta&amp;from=5000&amp;to=38469" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NG_008057.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_008057.1?report=genbank&amp;from=5000&amp;to=38469" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NG_008057.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_008057.1" sid="1" type="hidden" id="relString_NG_008057_1_4999_38468" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_008057.1&amp;from=1&amp;to=43488&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060935.1" sid="1" type="hidden" id="nucleotideLink_NC_060935_1_33840022_33873491" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060935.1?report=graph&amp;from=33835002&amp;to=33878511&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_060935.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060935.1?report=fasta&amp;from=33840023&amp;to=33873492&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_060935.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060935.1?report=genbank&amp;from=33840023&amp;to=33873492&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_060935.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060935.1" sid="1" type="hidden" id="relString_NC_060935_1_33840022_33873491" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060935.1&amp;from=33835002&amp;to=33878511&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000011.9" sid="1" type="hidden" id="nucleotideLink_NC_000011_9_33724555_33758024" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000011.9?report=graph&amp;from=33719535&amp;to=33763044&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.9">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000011.9?report=fasta&amp;from=33724556&amp;to=33758025&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.9">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000011.9?report=genbank&amp;from=33724556&amp;to=33758025&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=966&amp;link_uid=NC_000011.9">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000011.9" sid="1" type="hidden" id="relString_NC_000011_9_33724555_33758024" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000011.9&amp;from=33719535&amp;to=33763044&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/966/?report=expression" data-url="/gene/966/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/966" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '966_Adrenal_10wk_PRJNA270632', 'gene': 966, 'source_name': 'adrenal 10wk', 'full_rpkm': 12.1221, 'exp_rpkm': 12.1, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268112}, 'adrenal 16wk': {'id': '966_Adrenal_16wk_PRJNA270632', 'gene': 966, 'source_name': 'adrenal 16wk', 'full_rpkm': 15.2512, 'exp_rpkm': 15.3, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268113}, 'adrenal 18wk': {'id': '966_Adrenal_18wk_PRJNA270632', 'gene': 966, 'source_name': 'adrenal 18wk', 'full_rpkm': 24.0028, 'exp_rpkm': 24.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268114}, 'adrenal 20wk': {'id': '966_Adrenal_20wk_PRJNA270632', 'gene': 966, 'source_name': 'adrenal 20wk', 'full_rpkm': 19.513, 'exp_rpkm': 19.5, 'var': 14.23012, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268115}, 'heart 10wk': {'id': '966_Heart_10wk;_PRJNA270632', 'gene': 966, 'source_name': 'heart 10wk', 'full_rpkm': 5.14268, 'exp_rpkm': 5.14, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268116}, 'heart 11wk': {'id': '966_Heart_11wk;_PRJNA270632', 'gene': 966, 'source_name': 'heart 11wk', 'full_rpkm': 7.90409, 'exp_rpkm': 7.9, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268117}, 'heart 17wk': {'id': '966_Heart_17wk;_PRJNA270632', 'gene': 966, 'source_name': 'heart 17wk', 'full_rpkm': 8.05306, 'exp_rpkm': 8.05, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268118}, 'heart 18wk': {'id': '966_Heart_18wk;_PRJNA270632', 'gene': 966, 'source_name': 'heart 18wk', 'full_rpkm': 9.26482, 'exp_rpkm': 9.26, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268119}, 'heart 20wk': {'id': '966_Heart_20wk_PRJNA270632', 'gene': 966, 'source_name': 'heart 20wk', 'full_rpkm': 9.606, 'exp_rpkm': 9.61, 'var': 9.33933, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268120}, 'intestine 10wk': {'id': '966_Intestine_10wk_PRJNA270632', 'gene': 966, 'source_name': 'intestine 10wk', 'full_rpkm': 3.21631, 'exp_rpkm': 3.22, 'var': 0.582842, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268121}, 'intestine 11wk': {'id': '966_Intestine_11wk_PRJNA270632', 'gene': 966, 'source_name': 'intestine 11wk', 'full_rpkm': 4.58745, 'exp_rpkm': 4.59, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268122}, 'intestine 15wk': {'id': '966_Intestine_15wk_PRJNA270632', 'gene': 966, 'source_name': 'intestine 15wk', 'full_rpkm': 5.0711, 'exp_rpkm': 5.07, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268123}, 'intestine 17wk': {'id': '966_Intestine_17wk_PRJNA270632', 'gene': 966, 'source_name': 'intestine 17wk', 'full_rpkm': 3.09091, 'exp_rpkm': 3.09, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268124}, 'intestine 20wk': {'id': '966_Intestine_20wk_PRJNA270632', 'gene': 966, 'source_name': 'intestine 20wk', 'full_rpkm': 11.2497, 'exp_rpkm': 11.2, 'var': 0.241488, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268125}, 'kidney 10wk': {'id': '966_Kidney_10wk_PRJNA270632', 'gene': 966, 'source_name': 'kidney 10wk', 'full_rpkm': 6.64845, 'exp_rpkm': 6.65, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268126}, 'kidney 16wk': {'id': '966_Kidney_16wk_PRJNA270632', 'gene': 966, 'source_name': 'kidney 16wk', 'full_rpkm': 3.83261, 'exp_rpkm': 3.83, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268127}, 'kidney 20wk': {'id': '966_Kidney_20wk_PRJNA270632', 'gene': 966, 'source_name': 'kidney 20wk', 'full_rpkm': 2.14729, 'exp_rpkm': 2.15, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268128}, 'lung 10wk': {'id': '966_Lung_10wk_PRJNA270632', 'gene': 966, 'source_name': 'lung 10wk', 'full_rpkm': 4.80322, 'exp_rpkm': 4.8, 'var': 0.00654756, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268129}, 'lung 17wk': {'id': '966_Lung_17wk_PRJNA270632', 'gene': 966, 'source_name': 'lung 17wk', 'full_rpkm': 12.6778, 'exp_rpkm': 12.7, 'var': 0.969474, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268130}, 'lung 20wk': {'id': '966_Lung_20wk_PRJNA270632', 'gene': 966, 'source_name': 'lung 20wk', 'full_rpkm': 11.4621, 'exp_rpkm': 11.5, 'var': 12.90628, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268131}, 'stomach 10wk': {'id': '966_Stomach_10wk_PRJNA270632', 'gene': 966, 'source_name': 'stomach 10wk', 'full_rpkm': 3.8364, 'exp_rpkm': 3.84, 'var': 0.0459024, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268132}, 'stomach 16wk': {'id': '966_Stomach_16wk_PRJNA270632', 'gene': 966, 'source_name': 'stomach 16wk', 'full_rpkm': 9.57609, 'exp_rpkm': 9.58, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268133}, 'stomach 18wk': {'id': '966_Stomach_18wk_PRJNA270632', 'gene': 966, 'source_name': 'stomach 18wk', 'full_rpkm': 13.6406, 'exp_rpkm': 13.6, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268134}, 'stomach 20wk': {'id': '966_Stomach_20wk_PRJNA270632', 'gene': 966, 'source_name': 'stomach 20wk', 'full_rpkm': 14.3223, 'exp_rpkm': 14.3, 'var': 4.0971, 'project_desc': 'PRJNA270632', '_version_': 1785734389323268135}};
|
||
|
||
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||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 966, "sample_id": "SAMN03267754", "full_rpkm": 12.1221, "exp_rpkm": 12.1, "exp_total": 475327, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 966, "sample_id": "SAMN03267755", "full_rpkm": 15.2512, "exp_rpkm": 15.3, "exp_total": 895797, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 966, "sample_id": "SAMN03267761", "full_rpkm": 24.0028, "exp_rpkm": 24.0, "exp_total": 1294645, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", "exp_Mcount": 6675.41}], "adrenal 20wk": [{"id": "metadata_9606_SAMN03267762", "gene": 966, "sample_id": "SAMN03267762", "full_rpkm": 15.7407, "exp_rpkm": 15.7, "exp_total": 961740, "project_desc": "PRJNA270632", "_version_": 1785734387345653761, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 7561.75}, {"id": "metadata_9606_SAMN03267753", "gene": 966, "sample_id": "SAMN03267753", "full_rpkm": 23.2853, "exp_rpkm": 23.3, "exp_total": 1250784, "project_desc": "PRJNA270632", "_version_": 1785734387345653762, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 6647.98}], "heart 10wk": [{"id": "metadata_9606_SAMN03267750", "gene": 966, "sample_id": "SAMN03267750", "full_rpkm": 5.14268, "exp_rpkm": 5.14, "exp_total": 221899, "project_desc": "PRJNA270632", "_version_": 1785734387345653760, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 10wk", "exp_Mcount": 5340.16}], "heart 11wk": [{"id": "metadata_9606_SAMN03267763", "gene": 966, "sample_id": "SAMN03267763", "full_rpkm": 7.90409, "exp_rpkm": 7.9, "exp_total": 379172, "project_desc": "PRJNA270632", "_version_": 1785734387344605210, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 11wk", "exp_Mcount": 5937.09}], "heart 17wk": [{"id": "metadata_9606_SAMN03267757", "gene": 966, "sample_id": "SAMN03267757", "full_rpkm": 8.05306, "exp_rpkm": 8.05, "exp_total": 514541, "project_desc": "PRJNA270632", "_version_": 1785734387344605209, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 17wk", "exp_Mcount": 7907.66}], "heart 18wk": [{"id": "metadata_9606_SAMN03267751", "gene": 966, "sample_id": "SAMN03267751", "full_rpkm": 9.26482, "exp_rpkm": 9.26, "exp_total": 477673, "project_desc": "PRJNA270632", "_version_": 1785734387344605208, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 18wk", "exp_Mcount": 6380.91}], "heart 20wk": [{"id": "metadata_9606_SAMN03267756", "gene": 966, "sample_id": "SAMN03267756", "full_rpkm": 5.88561, "exp_rpkm": 5.89, "exp_total": 516285, "project_desc": "PRJNA270632", "_version_": 1785734387344605205, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 10856.4}, {"id": "metadata_9606_SAMN03267764", "gene": 966, "sample_id": "SAMN03267764", "full_rpkm": 13.3709, "exp_rpkm": 13.4, "exp_total": 550726, "project_desc": "PRJNA270632", "_version_": 1785734387344605206, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5097.56}, {"id": "metadata_9606_SAMN03267760", "gene": 966, "sample_id": "SAMN03267760", "full_rpkm": 9.56147, "exp_rpkm": 9.56, "exp_total": 463081, "project_desc": "PRJNA270632", "_version_": 1785734387344605207, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5994.06}], "intestine 10wk": [{"id": "metadata_9606_SAMN03267752", "gene": 966, "sample_id": "SAMN03267752", "full_rpkm": 2.45287, "exp_rpkm": 2.45, "exp_total": 154764, "project_desc": "PRJNA270632", "_version_": 1785734387344605203, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 7808.8}, {"id": "metadata_9606_SAMN03267759", "gene": 966, "sample_id": "SAMN03267759", "full_rpkm": 3.97975, "exp_rpkm": 3.98, "exp_total": 222099, "project_desc": "PRJNA270632", "_version_": 1785734387344605204, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 6906.84}], "intestine 11wk": [{"id": "metadata_9606_SAMN03267758", "gene": 966, "sample_id": "SAMN03267758", "full_rpkm": 4.58745, "exp_rpkm": 4.59, "exp_total": 160680, "project_desc": "PRJNA270632", "_version_": 1785734387344605202, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 11wk", "exp_Mcount": 4334.9}], "intestine 15wk": [{"id": "metadata_9606_SAMN03267775", "gene": 966, "sample_id": "SAMN03267775", "full_rpkm": 5.0711, "exp_rpkm": 5.07, "exp_total": 163097, "project_desc": "PRJNA270632", "_version_": 1785734387344605201, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 15wk", "exp_Mcount": 3980.45}], "intestine 17wk": [{"id": "metadata_9606_SAMN03267782", "gene": 966, "sample_id": "SAMN03267782", "full_rpkm": 3.09091, "exp_rpkm": 3.09, "exp_total": 241395, "project_desc": "PRJNA270632", "_version_": 1785734387344605200, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 17wk", "exp_Mcount": 9665.65}], "intestine 20wk": [{"id": "metadata_9606_SAMN03267766", "gene": 966, "sample_id": "SAMN03267766", "full_rpkm": 11.7411, "exp_rpkm": 11.7, "exp_total": 394771, "project_desc": "PRJNA270632", "_version_": 1785734387344605198, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 4161.26}, {"id": "metadata_9606_SAMN03267769", "gene": 966, "sample_id": "SAMN03267769", "full_rpkm": 10.7583, "exp_rpkm": 10.8, "exp_total": 338494, "project_desc": "PRJNA270632", "_version_": 1785734387344605199, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 3894.01}], "kidney 10wk": [{"id": "metadata_9606_SAMN03267784", "gene": 966, "sample_id": "SAMN03267784", "full_rpkm": 6.64845, "exp_rpkm": 6.65, "exp_total": 253856, "project_desc": "PRJNA270632", "_version_": 1785734387344605197, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 10wk", "exp_Mcount": 4725.59}], "kidney 16wk": [{"id": "metadata_9606_SAMN03267772", "gene": 966, "sample_id": "SAMN03267772", "full_rpkm": 3.83261, "exp_rpkm": 3.83, "exp_total": 473437, "project_desc": "PRJNA270632", "_version_": 1785734387344605196, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 16wk", "exp_Mcount": 15288.2}], "kidney 20wk": [{"id": "metadata_9606_SAMN03267777", "gene": 966, "sample_id": "SAMN03267777", "full_rpkm": 2.14729, "exp_rpkm": 2.15, "exp_total": 178360, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 966, "sample_id": "SAMN03267770", "full_rpkm": 4.88413, "exp_rpkm": 4.88, "exp_total": 234918, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 966, "sample_id": "SAMN03267767", "full_rpkm": 4.7223, "exp_rpkm": 4.72, "exp_total": 199605, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", 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"full_rpkm": 15.0546, "exp_rpkm": 15.1, "exp_total": 772732, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 966, "sample_id": "SAMN03267773", "full_rpkm": 3.62215, "exp_rpkm": 3.62, "exp_total": 192636, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 966, "sample_id": "SAMN03267779", "full_rpkm": 4.05065, "exp_rpkm": 4.05, "exp_total": 236764, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 966, "sample_id": "SAMN03267774", "full_rpkm": 9.57609, "exp_rpkm": 9.58, "exp_total": 481227, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 966, "sample_id": "SAMN03267771", "full_rpkm": 13.6406, "exp_rpkm": 13.6, "exp_total": 641501, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 966, "sample_id": "SAMN03267765", "full_rpkm": 16.355, "exp_rpkm": 16.4, "exp_total": 593953, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 966, "sample_id": "SAMN03267781", "full_rpkm": 11.5605, "exp_rpkm": 11.6, "exp_total": 426525, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 966, "sample_id": "SAMN03267783", "full_rpkm": 15.0513, "exp_rpkm": 15.1, "exp_total": 584306, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/26935178/" ref="ordinalpos=1&ncbi_uid=966&link_uid=26935178">The membrane complement regulatory protein CD59 promotes tumor growth and predicts poor prognosis in breast cancer.</a>
|
||
<span class="pubmed-auth-date"> Ouyang Q, <em>et al</em>. Int J Oncol, 2016 May. PMID 26935178</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/24036449/" ref="ordinalpos=2&ncbi_uid=966&link_uid=24036449">Hepatitis B virus core protein interacts with CD59 to promote complement-mediated liver inflammation during chronic hepatitis B virus infection.</a>
|
||
<span class="pubmed-auth-date"> Liu D, <em>et al</em>. FEBS Lett, 2013 Oct 11. PMID 24036449</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/24084445/" ref="ordinalpos=3&ncbi_uid=966&link_uid=24084445">Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice.</a>
|
||
<span class="pubmed-auth-date"> Li B, <em>et al</em>. Immunol Lett, 2013 Nov-Dec. PMID 24084445</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/24167638/" ref="ordinalpos=4&ncbi_uid=966&link_uid=24167638">Adeno-associated virus mediated delivery of a non-membrane targeted human soluble CD59 attenuates some aspects of diabetic retinopathy in mice.</a>
|
||
<span class="pubmed-auth-date"> Adhi M, <em>et al</em>. PLoS One, 2013. PMID 24167638, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3805538/" ref="ordinalpos=0&ncbi_uid=966&link_uid=PMC3805538">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/15147772/" ref="ordinalpos=5&ncbi_uid=966&link_uid=15147772">Heterogeneous expression of CD59 on human Purkinje cells.</a>
|
||
<span class="pubmed-auth-date"> Storstein A, <em>et al</em>. Neurosci Lett, 2004 May 13. PMID 15147772</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=966" title="See all 275 citations in Pubmed">See all (275) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/39435487" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=39435487">SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37522198" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=37522198">The bioinformatics analysis of CD59 in Helicobacter pylori infected gastric cancer.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: The bioinformatics analysis of CD59 in Helicobacter pylori infected gastric cancer.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37050931" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=37050931">Multiple CD59 Polymorphisms in Chinese Patients with Mycobacterium tuberculosis Infection.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: Multiple CD59 Polymorphisms in Chinese Patients with Mycobacterium tuberculosis Infection.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36396448" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=36396448">CD59 Expression in Skeletal Muscles and Its Role in Myasthenia Gravis.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: CD59 Expression in Skeletal Muscles and Its Role in Myasthenia Gravis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35907507" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=35907507">The utility of first trimester plasma glycated CD59 (pGCD59) in predicting gestational diabetes mellitus: A prospective study of non-diabetic pregnant women in Ireland.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: The utility of first trimester plasma glycated CD59 (pGCD59) in predicting gestational diabetes mellitus: A prospective study of non-diabetic pregnant women in Ireland.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35666870" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=35666870">Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35443950" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=35443950">Plasma-glycated CD59 as an early biomarker for gestational diabetes mellitus: prospective cohort study protocol.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Plasma-glycated CD59 as an early biomarker for gestational diabetes mellitus: prospective cohort study protocol.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32290641" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=32290641">Serum CD59: a novel biomarker of idiopathic pulmonary fibrosis?</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: Serum CD59: a novel biomarker of idiopathic pulmonary fibrosis?</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32940116" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=32940116">The value of p16 and HPV DNA in non-tonsillar, non-base of tongue oropharyngeal cancer.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: The value of p16 and HPV DNA in non-tonsillar, non-base of tongue oropharyngeal cancer.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/34524975" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=966&link_uid=34524975">Plasma glycated CD59 predicts postpartum glucose intolerance after gestational diabetes.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: Plasma glycated CD59 predicts postpartum glucose intolerance after gestational diabetes.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=966&sym=CD59&name=CD59 molecule (CD59 blood group)&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=966&symbol=CD59;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=966" class="seeall-generif">See all GeneRIFs (136)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=CD59[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=966">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="associatedconditions">Associated conditions</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
<th>Tests</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>
|
||
<a href="/gtr/conditions/C2676767" ref="ncbi_uid=966&link_uid=C2676767">Primary CD59 deficiency</a>
|
||
<div class="gtr-associated-cond-extra">
|
||
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C2676767" ref="ncbi_uid=966&link_uid=C2676767">C2676767</a></span>
|
||
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/612300" ref="ncbi_uid=966"> 612300</a></span>
|
||
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
|
||
</div>
|
||
</td>
|
||
<td>
|
||
<a href="/gtr/tests/?term=C2676767[DISCUI]&condition=C2676767&compare_labs=1" ref="ncbi_uid=966">Compare labs</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=CD59[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=966" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=966[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=966[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="replicationinteractions">Replication interactions</h3>
|
||
<table summary="replication interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivinter">HIV-1 replication requires CD59 as cells lacking CD59 did not support efficient viral replication</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 27231035" href="/pubmed/27231035">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28876544">Envelope surface glycoprotein gp120</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Env (gp120) co-localizes with human CD59 in lipid rafts on the surface of Jurkat cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 27231035" href="/pubmed/27231035">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 gp120 co-localizes with human CD59 in lipid rafts on the surface of ACH-2 cells upon provirus activation</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 25149467" href="/pubmed/25149467">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">The complement regulatory proteins CD55 (DAF) and CD59 (HRF20) exist on HIV-1 virions, along with HIV-1 gp120 molecules, suggesting an interaction between these proteins and gp120</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 24639397,19955519,8887350" href="/pubmed/24639397,19955519,8887350">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 gp120 induces CD4 association with lymphocyte surface molecules CD3, CD11a, CD27, CD45RA, CD45RB, CD45RO, CD49d, CD38, CD26, CD59, CD95 and class I MHC molecules</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 9263011" href="/pubmed/9263011">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">Treatment of CD4+ T cells with HIV-1 gp120 significantly increases CD4 association with CD3, CD45RA, CD45RB, CD59, CD38, CD26 and HLA class I, and decreases that with CD45RC</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 9263011,7539755" href="/pubmed/9263011,7539755">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/19172954">Envelope transmembrane glycoprotein gp41</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">A peptide corresponding to the amino acids 598-613 of HIV-1 gp41, as well as recombinant gp41 protein, markedly reduce CD59 levels in a dose dependent manner in human neuronal and glial cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 10786997" href="/pubmed/10786997">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28872818">Nef</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/156110">nef</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Nef induces release of CD59 (MAL-dependent exosome marker) from Jurkat T cells transfected with DNA constructs coding for Nef-GFP</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 26109641" href="/pubmed/26109641">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629360">Pr55(Gag)</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Gag P99A mutation reduces its co-localization with tetraspanin-enriched microdomain marker CD81 and lipid raft marker CD59</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 21813604" href="/pubmed/21813604">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">HIV Gag proteins adopt a ring-like supramolecular organization at sites of intercellular contacts and co-localize with CD63 tetraspanin and raft components GM1, Thy-1, and CD59</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 21813604,19369333" href="/pubmed/21813604,19369333">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">The highly basic region (HBR) of HIV-1 MA promotes Gag association with specific UDMs containing PSGL-1, CD43, and CD59</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 23536680" href="/pubmed/23536680">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">The Matrix protein of HIV-1 Gag colocalizes with CD59 in lipid rafts, the site of virus particle budding from cells, and CD59 is incorporated into virus particles as a result of this process</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 10708443" href="/pubmed/10708443">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28876542">matrix</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">The highly basic region (HBR) of HIV-1 MA promotes Gag association with specific UDMs containing PSGL-1, CD43, and CD59</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 23536680" href="/pubmed/23536680">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Matrix co-localizes with CD59 in lipid rafts, the site of virus particle budding from cells, and CD59 is incorporated into virus particles as a result of this process</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 10708443" href="/pubmed/10708443">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-pathways">
|
||
<section class="rprt-section-header" id="pathways">
|
||
<h2 id="header-pathways">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<ul class="geneinfo-subsec infopathway">
|
||
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/966#section=Pathways&embed=true&hide_all_headings=true&page_size=25" style="border: 0; width: 100%;"></iframe>
|
||
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
|
||
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/966/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH18284 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=4364%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=4364">UniSTS:4364</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">HUM0S15C02 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=40486%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=40486">UniSTS:40486</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D8S2279 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=473907%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=473907">UniSTS:473907</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D11S4339 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=70461%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=70461">UniSTS:70461</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D11S3984 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=53573%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=53573">UniSTS:53573</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">STS-N37061 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=30793%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=30793">UniSTS:30793</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D11S4717 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=61008%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=61008">UniSTS:61008</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">A004V27 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=13910%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=13910">UniSTS:13910</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">STS-M34671 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=70269%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=70269">UniSTS:70269</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">RH44913 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=69024%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=69024">UniSTS:69024</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">CD59_1802 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=280486%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=280486">UniSTS:280486</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-32142 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=25037%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=25037">UniSTS:25037</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH45061 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=7658%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=7658">UniSTS:7658</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">CD59 (e-PCR), detects polymorphism<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=59389%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=966&link_uid=59389">UniSTS:59389</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/966/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
<div class="infosec info-comment" id="info-comment">
|
||
<h3 id="CloneNames">
|
||
<a class="jig-ncbitoggler-open">Clone Names</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>MGC2354, FLJ38134, FLJ92039 </li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0001848">enables complement binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/17500595,20427317,24036449,32296183,32814053" target="_blank" title="PubMed ID 17500595,20427317,24036449,32296183,32814053" ref="ordinalpos=1&ncbi_uid=966&link_uid=17500595,20427317,24036449,32296183,32814053">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0007596">involved_in blood coagulation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-1-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/1381503" target="_blank" title="PubMed ID 1381503" ref="ordinalpos=1&ncbi_uid=966&link_uid=1381503">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0007166">involved_in cell surface receptor signaling pathway</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-2-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/7691713" target="_blank" title="PubMed ID 7691713" ref="ordinalpos=1&ncbi_uid=966&link_uid=7691713">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0001971">involved_in negative regulation of activation of membrane attack complex</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-3-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0030449">acts_upstream_of_or_within regulation of complement activation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/25284781" target="_blank" title="PubMed ID 25284781" ref="ordinalpos=1&ncbi_uid=966&link_uid=25284781">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:1903659">acts_upstream_of_or_within regulation of complement-dependent cytotoxicity</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/25284781" target="_blank" title="PubMed ID 25284781" ref="ordinalpos=1&ncbi_uid=966&link_uid=25284781">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0012507">located_in ER to Golgi transport vesicle membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-1-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0000139">located_in Golgi membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-2-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0009986">located_in cell surface</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/15907827" target="_blank" title="PubMed ID 15907827" ref="ordinalpos=1&ncbi_uid=966&link_uid=15907827">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005789">located_in endoplasmic reticulum membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0033116">located_in endoplasmic reticulum-Golgi intermediate compartment membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-5-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0009897">located_in external side of plasma membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-6-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/9724629" target="_blank" title="PubMed ID 9724629" ref="ordinalpos=1&ncbi_uid=966&link_uid=9724629">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0070062">located_in extracellular exosome</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
|
||
<div id="evidence-code-7-2" class="ecode">
|
||
<br />
|
||
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
|
||
</div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/19056867,19199708,20458337,23533145" target="_blank" title="PubMed ID 19056867,19199708,20458337,23533145" ref="ordinalpos=1&ncbi_uid=966&link_uid=19056867,19199708,20458337,23533145">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005615">located_in extracellular space</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
|
||
<div id="evidence-code-8-2" class="ecode">
|
||
<br />
|
||
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
|
||
</div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/16502470" target="_blank" title="PubMed ID 16502470" ref="ordinalpos=1&ncbi_uid=966&link_uid=16502470">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005925">located_in focal adhesion</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
|
||
<div id="evidence-code-9-2" class="ecode">
|
||
<br />
|
||
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
|
||
</div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/21423176" target="_blank" title="PubMed ID 21423176" ref="ordinalpos=1&ncbi_uid=966&link_uid=21423176">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016020">located_in membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-10-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/1381503" target="_blank" title="PubMed ID 1381503" ref="ordinalpos=1&ncbi_uid=966&link_uid=1381503">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">is_active_in plasma membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-11-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-12-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035579">located_in specific granule membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-13-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0070821">located_in tertiary granule membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-14-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0030133">located_in transport vesicle</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-15-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0031982">located_in vesicle</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
|
||
<div id="evidence-code-16-2" class="ecode">
|
||
<br />
|
||
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
|
||
</div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/19190083" target="_blank" title="PubMed ID 19190083" ref="ordinalpos=1&ncbi_uid=966&link_uid=19190083">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>CD59 glycoprotein</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>1F5 antigen</dd>
|
||
<dd>20 kDa homologous restriction factor</dd>
|
||
<dd>CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)</dd>
|
||
<dd>CD59 blood group antigen</dd>
|
||
<dd>CD59 molecule, complement regulatory protein</dd>
|
||
<dd>Ly-6-like protein</dd>
|
||
<dd>MEM43 antigen</dd>
|
||
<dd>T cell-activating protein</dd>
|
||
<dd>human leukocyte antigen MIC11</dd>
|
||
<dd>lymphocytic antigen CD59/MEM43</dd>
|
||
<dd>membrane attack complex (MAC) inhibition factor</dd>
|
||
<dd>membrane attack complex inhibition factor</dd>
|
||
<dd>membrane inhibitor of reactive lysis</dd>
|
||
<dd>protectin</dd>
|
||
<dd>surface anitgen recognized by monoclonal antibody 16.3A5</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=966&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p87826272">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_008057.1 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5000..38469</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_008057.1?from=5000&to=38469&report=genbank" ref="ordinalpos=1&ncbi_uid=966&link_uid=NG_008057.1?from=5000&to=38469&report=genbank">GenBank</a>, <a href="/nuccore/NG_008057.1?from=5000&to=38469&report=fasta" ref="ordinalpos=1&ncbi_uid=966&link_uid=NG_008057.1?from=5000&to=38469&report=fasta">FASTA</a>, <a href="/nuccore/NG_008057.1?from=1&to=43488&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=966&link_uid=NG_008057.1?from=1&to=43488&report=graph&content=5">Sequence Viewer (Graphics)</a>, <a href="ftp://ftp.ebi.ac.uk/pub/databases/lrgex/LRG_41.xml">LRG_41</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p87570928">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_000611.6">NM_000611.6</a> → <a href="/protein/NP_000602.1">NP_000602.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_000602.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_000602.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU136899, BC001506, BM680161">AL049629, AU136899, BC001506, BM680161</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000494884.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000494884.1</a>, <a href="http://www.ensembl.org/id/ENST00000642928.2" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000642928.2</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_000602.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001127223.1">NM_001127223.1</a> → <a href="/protein/NP_001120695.1">NP_001120695.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_001120695.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_001120695.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AK309894, AL049629, BM680161">AK309894, AL049629, BM680161</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000404822.2" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000404822.2</a>, <a href="http://www.ensembl.org/id/ENST00000415002.7" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000415002.7</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001120695.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001127225.2">NM_001127225.2</a> → <a href="/protein/NP_001120697.1">NP_001120697.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_001120697.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_001120697.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU139541, BM680161, DA840870">AL049629, AU139541, BM680161, DA840870</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000410182.2" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000410182.2</a>, <a href="http://www.ensembl.org/id/ENST00000437761.6" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000437761.6</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001120697.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001127226.2">NM_001127226.2</a> → <a href="/protein/NP_001120698.1">NP_001120698.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_001120698.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_001120698.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU139541, BM680161">AL049629, AU139541, BM680161</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000403511.2" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000403511.2</a>, <a href="http://www.ensembl.org/id/ENST00000445143.6" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000445143.6</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001120698.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001127227.2">NM_001127227.2</a> → <a href="/protein/NP_001120699.1">NP_001120699.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_001120699.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_001120699.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU139009, BM680161">AL049629, AU139009, BM680161</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000498448.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000498448.1</a>, <a href="http://www.ensembl.org/id/ENST00000652678.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000652678.1</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001120699.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_203329.3">NM_203329.3</a> → <a href="/protein/NP_976074.1">NP_976074.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_976074.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_976074.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, BM680161, DA578905">AL049629, BM680161, DA578905</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000432942.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000432942.1</a>, <a href="http://www.ensembl.org/id/ENST00000527577.5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000527577.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_976074.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_203330.2">NM_203330.2</a> → <a href="/protein/NP_976075.1">NP_976075.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_976075.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_976075.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) encodes the same protein as variants 2-8.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU136899, BM680161, DA250543">AL049629, AU136899, BM680161, DA250543</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000498879.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000498879.1</a>, <a href="http://www.ensembl.org/id/ENST00000651785.1" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000651785.1</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_976075.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_203331.3">NM_203331.3</a> → <a href="/protein/NP_976076.1">NP_976076.1</a> CD59 glycoprotein preproprotein</p>
|
||
<p>
|
||
<a href="/ipg/NP_976076.1/" ref="ncbi_uid=966">See identical proteins and their annotated locations for NP_976076.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All variants (1-8) encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL049629, AU136899, BM680161, DA917093">AL049629, AU136899, BM680161, DA917093</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7886.1">CCDS7886.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E9PR17" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">E9PR17</a>, <a href="https://www.uniprot.org/uniprot/P13987" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">P13987</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0A2U3TZL5" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">A0A2U3TZL5</a>, <a href="https://www.uniprot.org/uniprot/Q6FHM9" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">Q6FHM9</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000340210.3" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENSP00000340210.3</a>, <a href="http://www.ensembl.org/id/ENST00000351554.8" ref="itool=Gene_FullReport&PrId=5380&uid=966&nlmid=&db=gene">ENST00000351554.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_976076.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238065">cd00117</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">26</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p87551904">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p87551904">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000011.10 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>33703010..33736479 complement</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000011.10?from=33703010&to=33736479&report=genbank&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10?from=33703010&to=33736479&report=genbank&strand=true">GenBank</a>, <a href="/nuccore/NC_000011.10?from=33703010&to=33736479&report=fasta&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10?from=33703010&to=33736479&report=fasta&strand=true">FASTA</a>, <a href="/nuccore/NC_000011.10?from=33697989&to=33741498&report=graph&content=5&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_000011.10?from=33697989&to=33741498&report=graph&content=5&strand=true">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p87561040">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p87561040">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060935.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>33840023..33873492 complement</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060935.1?from=33840023&to=33873492&report=genbank&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_060935.1?from=33840023&to=33873492&report=genbank&strand=true">GenBank</a>, <a href="/nuccore/NC_060935.1?from=33840023&to=33873492&report=fasta&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_060935.1?from=33840023&to=33873492&report=fasta&strand=true">FASTA</a>, <a href="/nuccore/NC_060935.1?from=33835002&to=33878511&report=graph&content=5&strand=true" ref="ordinalpos=1&ncbi_uid=966&link_uid=NC_060935.1?from=33835002&to=33878511&report=graph&content=5&strand=true">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/966/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">P13987.1</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/116021" ref="ordinalpos=1&ncbi_uid=966&link_uid=116021">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/P13987">UniProtKB/Swiss-Prot:P13987</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="lsdb"><h3 class="withnote" id="locusspecificdatabases"><a class="jig-ncbitoggler-open">Locus-specific Databases</a></h3><div><ul class="locusdb"><li><a href="http://structure.bmc.lu.se/idbase/CD59base/" ref="from_uid=966" class="lsdblink">CD59base: Mutation registry for CD59 deficiency</a></li><li><a href="http://databases.lovd.nl/shared/genes/CD59" ref="from_uid=966" class="lsdblink">CD59 database</a></li></ul></div></div>
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/CD59?lang=en&region=US" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>CD59 products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000085063" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>CD59 gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/966/" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (12 hits/1387 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&format=genome&entry=CD59_1" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9624">
|
||
<span>CD59_1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/P13987" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span><span class="regis-rsc"></span>Human Gene Mutation Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.hgmd.cf.ac.uk/ac/gene.php?gene=CD59" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=3100">
|
||
<span>Human Gene Mutation Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D966%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=38813" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000085063" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05308/" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05301/" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05306/" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Gene Wiki</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://en.wikipedia.org/wiki/CD59" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=6933">
|
||
<span>The Gene Wiki</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=CD59" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for CD59</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/cd59/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CD59 Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/cd59/elisa-kits?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=elisakits" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CD59 ELISA Kits</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/cd59b/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CD59b Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Creative Biogene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.creative-biogene.com/genesearch/CD59.html" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=10094">
|
||
<span>CD59 molecule, complement regulatory protein</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/CD59-antibody.html" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/CD59-antibody.html" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=22&field=5&key=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order promoter clone</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&field=5&key=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order shRNA clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=966&type=01&page=1" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=CD59;" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=3267">
|
||
<span>Kazusa DNA Research Institute</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=CD59" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order CD59 cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=966" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Miscellaneous</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Reactome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-168256" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Immune System</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-5653656" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Vesicle-mediated transport</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-392499" ref="itool=Gene_FullReport&uid=966&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Metabolism of proteins</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#pathways">Pathways from PubChem</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
<div class="subsection-links">
|
||
<a href="#lsdb">Locus-specific Databases</a>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/966" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&from_uid=966" ref="log$=recordlinks">3D structures</a>
|
||
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=966" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=966" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=966" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=966" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=966" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=966" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=966" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=966" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=966" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=966" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=966" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=966" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=966" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=966" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=966" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=966" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=966[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=966" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/medgen?LinkName=gene_medgen_diseases&from_uid=966" ref="log$=recordlinks">MedGen</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=966" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=966" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=966" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=966" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=966" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=966" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=966" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=966" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=966" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=966" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=966" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=966" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/190570182?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=966" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=966" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=966" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=966[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1689">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000085063">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:1689">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=966">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://databases.lovd.nl/shared/genes/CD59">CD59 database</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://structure.bmc.lu.se/idbase/CD59base/">CD59base: Mutation registry for CD59 deficiency</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.pharmgkb.org/gene/PA26228">PharmGKB</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_001127223">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC001506">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=CD59&geneID=966&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:966">KEGG</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=966&symbol=CD59">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=966&sym=CD59&name=CD59 molecule (CD59 blood group)&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9d9b484f3725e591024c5">CD59 CD59 molecule (CD59 blood group) [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">CD59 CD59 molecule (CD59 blood group) [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:966</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9d9b284f3725e5910192a">CD59 glycoprotein preproprotein [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">CD59 glycoprotein preproprotein [Homo sapiens]<div class="brieflinkpopdesc">gi|10835165|ref|NP_000602.1|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9d9b0f4a390645e1013bf">CD58 CD58 molecule [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">CD58 CD58 molecule [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:965</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9d9afb15b832ebce41f42">lymphocyte function-associated antigen 3 isoform 1 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">lymphocyte function-associated antigen 3 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|4502677|ref|NP_001770.1|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9d9ac84f3725e590ff02e">CD55 CD55 molecule (Cromer blood group) [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">CD55 CD55 molecule (Cromer blood group) [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:1604</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
</ul>
|
||
<p class="HTOn">Your browsing activity is empty.</p>
|
||
<p class="HTOff">Activity recording is turned off.</p>
|
||
<p id="turnOn" class="HTOff">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
|
||
</p>
|
||
<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="NCBIFooter_dynamic">
|
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