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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'7184',linkname:'',idsfromresult:'7514',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67ca001369195c35ad75d5ee" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="7184" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">XPO1</span> exportin 1 [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 7514, updated on
4-Mar-2025</span>
</div>
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<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
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<div class="rprt-body">
<div class="rprt-section gene-summary">
<section class="rprt-section-header" id="summary">
<h2 id="header-summary">
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<div id="summaryDiv" class="section">
<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">XPO1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>exportin 1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12825" data-gblink-text="Ensembl">HGNC:HGNC:12825</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000082898" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000082898">Ensembl:ENSG00000082898</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/602559" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=602559">MIM:602559;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:12825" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=HGNC:12825">AllianceGenome:HGNC:12825</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>REVIEWED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Also known as</dt>
<dd>emb; CRM1; exp1; CRM-1</dd>
<dt>Summary</dt>
<dd>This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jan 2015]</dd>
<dt>Expression</dt>
<dd>Ubiquitous expression in testis (RPKM 38.6), lymph node (RPKM 33.8) and 25 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/103573">mouse</a>
<a href="/gene/7514/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7514/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7514/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
</div>
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</div>
<div class="rprt-section gene-genomic-context">
<section class="rprt-section-header" id="genomic-context">
<h2 id="header-genomic-context">
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<span class="ui-ncbitoggler-master-text">Genomic context</span>
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</h2>
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</section>
<div class="rprt-section-body">
<div class="gc_cont">
<div class="gt_cont_contents">
<div style="float:right"><span>See XPO1 in </span><a href="/genome/gdv/?context=gene&amp;acc=7514" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">2p15</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>31</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=7514&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>2</td>
<td>NC_000002.12 (61477849..61538612, complement) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=7514&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>2</td>
<td>NC_060926.1 (61483936..61544825, complement) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=7514&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>2</td>
<td>NC_000002.11 (61704984..61765491, complement) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome 2 - NC_000002.12</strong><img usemap="#nbrMap7514_568815596" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=7514&amp;nuc_gi=568815596&amp;n0=USP34&amp;n1=BNIP3P45&amp;n2=LOC126806224&amp;n3=LOC127273451&amp;n4=LOC129660700&amp;n5=SNORA70B&amp;n6=LOC127273452&amp;n7=LOC127273453&amp;n8=LOC127273454&amp;n9=LOC129660701&amp;n10=LOC129933830&amp;n11=LOC129388867&amp;n12=LOC122757951&amp;n13=LOC129933831&amp;n14=LOC127273455&amp;n15=LOC127273456&amp;n16=LOC127273457&amp;n17=LOC129933832&amp;n18=LOC129933833&amp;n19=LOC129933834&amp;n20=USP34-DT&amp;n21=XPO1&amp;n22=LOC129388868&amp;n23=LOC129388869&amp;n24=LOC127273458&amp;n25=LOC129933835&amp;n26=LOC129933836&amp;n27=LOC129933837&amp;n28=LOC127273459&amp;n29=LOC100422418&amp;n30=LOC127273460&amp;n31=RPS29P10" /><map name="nbrMap7514_568815596" id="nbrMap7514_568815596">
<area shape="rect" onMouseOver="showtip(this,event,'ubiquitin specific peptidase 34')" onMouseOut="hidetip()" coords="37,23,317,31" alt="Neighboring gene ubiquitin specific peptidase 34" href="/gene/9736" />
<area shape="rect" onMouseOver="showtip(this,event,'BNIP3 pseudogene 45')" onMouseOut="hidetip()" coords="78,35,128,43" alt="Neighboring gene BNIP3 pseudogene 45" href="/gene/127379725" />
<area shape="rect" onMouseOver="showtip(this,event,'MED14-independent group 3 enhancer GRCh37_chr2:61504619-61505818')" onMouseOut="hidetip()" coords="82,47,152,55" alt="Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:61504619-61505818" href="/gene/126806224" />
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr2:61607882-61608383')" onMouseOut="hidetip()" coords="175,35,245,43" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr2:61607882-61608383" href="/gene/127273451" />
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:61644005-61644197')" onMouseOut="hidetip()" coords="207,47,277,55" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:61644005-61644197" href="/gene/129660700" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:61652307-61652984')" onMouseOut="hidetip()" coords="214,59,284,67" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:61652307-61652984" href="/gene/127273452" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:61652985-61653662')" onMouseOut="hidetip()" coords="215,71,285,79" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:61652985-61653662" href="/gene/127273453" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:61653663-61654340')" onMouseOut="hidetip()" coords="215,83,285,91" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:61653663-61654340" href="/gene/127273454" />
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:61657175-61657369')" onMouseOut="hidetip()" coords="219,95,289,103" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:61657175-61657369" href="/gene/129660701" />
<area shape="rect" onMouseOver="showtip(this,event,'small nucleolar RNA, H/ACA box 70B')" onMouseOut="hidetip()" coords="227,107,277,115" alt="Neighboring gene small nucleolar RNA, H/ACA box 70B" href="/gene/100124537" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 11526')" onMouseOut="hidetip()" coords="237,119,307,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11526" href="/gene/129933830" />
<area shape="rect" onMouseOver="showtip(this,event,'MPRA-validated peak3715 silencer')" onMouseOut="hidetip()" coords="245,131,315,139" alt="Neighboring gene MPRA-validated peak3715 silencer" href="/gene/129388867" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 6736')" onMouseOut="hidetip()" coords="245,143,315,151" alt="Neighboring gene Sharpr-MPRA regulatory region 6736" href="/gene/122757951" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 15830')" onMouseOut="hidetip()" coords="249,35,319,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15830" href="/gene/129933831" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:61692432-61692952')" onMouseOut="hidetip()" coords="250,155,320,163" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:61692432-61692952" href="/gene/127273455" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:61692953-61693472')" onMouseOut="hidetip()" coords="250,167,320,175" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:61692953-61693472" href="/gene/127273456" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr2:61694001-61694500')" onMouseOut="hidetip()" coords="251,179,321,187" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:61694001-61694500" href="/gene/127273457" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 11527')" onMouseOut="hidetip()" coords="255,191,325,199" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11527" href="/gene/129933832" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 11528')" onMouseOut="hidetip()" coords="255,203,325,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11528" href="/gene/129933833" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 11529')" onMouseOut="hidetip()" coords="255,215,325,223" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11529" href="/gene/129933834" />
<area shape="rect" onMouseOver="showtip(this,event,'MPRA-validated peak3716 silencer')" onMouseOut="hidetip()" coords="261,227,331,235" alt="Neighboring gene MPRA-validated peak3716 silencer" href="/gene/129388868" />
<area shape="rect" onMouseOver="showtip(this,event,'USP34 divergent transcript')" onMouseOut="hidetip()" coords="275,239,329,247" alt="Neighboring gene USP34 divergent transcript" href="/gene/105377633" />
<area shape="rect" onMouseOver="showtip(this,event,'MPRA-validated peak3717 silencer')" onMouseOut="hidetip()" coords="289,47,359,55" alt="Neighboring gene MPRA-validated peak3717 silencer" href="/gene/129388869" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:61743599-61744099')" onMouseOut="hidetip()" coords="296,59,366,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:61743599-61744099" href="/gene/127273458" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 15831')" onMouseOut="hidetip()" coords="313,83,383,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15831" href="/gene/129933835" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 15832')" onMouseOut="hidetip()" coords="314,95,384,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15832" href="/gene/129933836" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 15833')" onMouseOut="hidetip()" coords="315,107,385,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15833" href="/gene/129933837" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr2:61766044-61766833')" onMouseOut="hidetip()" coords="316,119,386,127" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:61766044-61766833" href="/gene/127273459" />
<area shape="rect" onMouseOver="showtip(this,event,'proteasome 26S subunit, non-ATPase 12 pseudogene')" onMouseOut="hidetip()" coords="349,23,419,31" alt="Neighboring gene proteasome 26S subunit, non-ATPase 12 pseudogene" href="/gene/100422418" />
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:61809253-61809844')" onMouseOut="hidetip()" coords="353,35,423,43" alt="Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:61809253-61809844" href="/gene/127273460" />
<area shape="rect" onMouseOver="showtip(this,event,'ribosomal protein S29 pseudogene 10')" onMouseOut="hidetip()" coords="373,47,423,55" alt="Neighboring gene ribosomal protein S29 pseudogene 10" href="/gene/100132037" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="7514">
<option value="NC_000002.12_61477848_61538611">NC_000002.12 Chromosome 2 Reference GRCh38.p14 Primary Assembly</option>
<option value="NC_060926.1_61483935_61544824">NC_060926.1 Chromosome 2 Alternate T2T-CHM13v2.0</option>
<option value="NC_000002.11_61704983_61765490">NC_000002.11 Chromosome 2 Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000002" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&amp;from=61468734&amp;to=61547725&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&amp;from=61477849&amp;to=61538612&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&amp;from=61477849&amp;to=61538612&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12">GenBank</a>
</p>
<div id="divNC_000002" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.12&amp;from=61468734&amp;to=61547725&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.12&amp;from=61468734&amp;to=61547725&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.12" sid="1" type="hidden" id="nucleotideLink_NC_000002_12_61477848_61538611" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000002.12?report=graph&amp;amp;from=61468734&amp;amp;to=61547725&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.12&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000002.12?report=fasta&amp;amp;from=61477849&amp;amp;to=61538612&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.12&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000002.12?report=genbank&amp;amp;from=61477849&amp;amp;to=61538612&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.12&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.12" sid="1" type="hidden" id="relString_NC_000002_12_61477848_61538611" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000002.12&amp;amp;from=61468734&amp;amp;to=61547725&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060926.1" sid="1" type="hidden" id="nucleotideLink_NC_060926_1_61483935_61544824" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060926.1?report=graph&amp;amp;from=61474802&amp;amp;to=61553957&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_060926.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060926.1?report=fasta&amp;amp;from=61483936&amp;amp;to=61544825&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_060926.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060926.1?report=genbank&amp;amp;from=61483936&amp;amp;to=61544825&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_060926.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060926.1" sid="1" type="hidden" id="relString_NC_060926_1_61483935_61544824" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060926.1&amp;amp;from=61474802&amp;amp;to=61553957&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.11" sid="1" type="hidden" id="nucleotideLink_NC_000002_11_61704983_61765490" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000002.11?report=graph&amp;amp;from=61695907&amp;amp;to=61774566&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.11&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000002.11?report=fasta&amp;amp;from=61704984&amp;amp;to=61765491&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.11&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000002.11?report=genbank&amp;amp;from=61704984&amp;amp;to=61765491&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7514&amp;amp;link_uid=NC_000002.11&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.11" sid="1" type="hidden" id="relString_NC_000002_11_61704983_61765490" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000002.11&amp;amp;from=61695907&amp;amp;to=61774566&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/7514/?report=expression" data-url="/gene/7514/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/7514" data-report-type="summary">
<div>
<script type="text/javascript">
window.tissues_data = {'adrenal 10wk': {'id': '7514_Adrenal_10wk_PRJNA270632', 'gene': 7514, 'source_name': 'adrenal 10wk', 'full_rpkm': 19.9688, 'exp_rpkm': 20.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596188}, 'adrenal 16wk': {'id': '7514_Adrenal_16wk_PRJNA270632', 'gene': 7514, 'source_name': 'adrenal 16wk', 'full_rpkm': 11.2183, 'exp_rpkm': 11.2, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596189}, 'adrenal 18wk': {'id': '7514_Adrenal_18wk_PRJNA270632', 'gene': 7514, 'source_name': 'adrenal 18wk', 'full_rpkm': 13.7115, 'exp_rpkm': 13.7, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596190}, 'adrenal 20wk': {'id': '7514_Adrenal_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'adrenal 20wk', 'full_rpkm': 10.77, 'exp_rpkm': 10.8, 'var': 1.570958, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596191}, 'heart 10wk': {'id': '7514_Heart_10wk;_PRJNA270632', 'gene': 7514, 'source_name': 'heart 10wk', 'full_rpkm': 29.7463, 'exp_rpkm': 29.7, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596192}, 'heart 11wk': {'id': '7514_Heart_11wk;_PRJNA270632', 'gene': 7514, 'source_name': 'heart 11wk', 'full_rpkm': 20.4608, 'exp_rpkm': 20.5, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596193}, 'heart 17wk': {'id': '7514_Heart_17wk;_PRJNA270632', 'gene': 7514, 'source_name': 'heart 17wk', 'full_rpkm': 15.3393, 'exp_rpkm': 15.3, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596194}, 'heart 18wk': {'id': '7514_Heart_18wk;_PRJNA270632', 'gene': 7514, 'source_name': 'heart 18wk', 'full_rpkm': 14.9404, 'exp_rpkm': 14.9, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596195}, 'heart 20wk': {'id': '7514_Heart_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'heart 20wk', 'full_rpkm': 18.9731, 'exp_rpkm': 19.0, 'var': 16.8621, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596196}, 'intestine 10wk': {'id': '7514_Intestine_10wk_PRJNA270632', 'gene': 7514, 'source_name': 'intestine 10wk', 'full_rpkm': 28.7088, 'exp_rpkm': 28.7, 'var': 96.1824, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596197}, 'intestine 11wk': {'id': '7514_Intestine_11wk_PRJNA270632', 'gene': 7514, 'source_name': 'intestine 11wk', 'full_rpkm': 33.0288, 'exp_rpkm': 33.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596198}, 'intestine 15wk': {'id': '7514_Intestine_15wk_PRJNA270632', 'gene': 7514, 'source_name': 'intestine 15wk', 'full_rpkm': 20.1552, 'exp_rpkm': 20.2, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596199}, 'intestine 17wk': {'id': '7514_Intestine_17wk_PRJNA270632', 'gene': 7514, 'source_name': 'intestine 17wk', 'full_rpkm': 9.98621, 'exp_rpkm': 9.99, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596200}, 'intestine 20wk': {'id': '7514_Intestine_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'intestine 20wk', 'full_rpkm': 24.3191, 'exp_rpkm': 24.3, 'var': 0.39137, 'project_desc': 'PRJNA270632', '_version_': 1785734406901596201}, 'kidney 10wk': {'id': '7514_Kidney_10wk_PRJNA270632', 'gene': 7514, 'source_name': 'kidney 10wk', 'full_rpkm': 28.1127, 'exp_rpkm': 28.1, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644736}, 'kidney 16wk': {'id': '7514_Kidney_16wk_PRJNA270632', 'gene': 7514, 'source_name': 'kidney 16wk', 'full_rpkm': 12.6038, 'exp_rpkm': 12.6, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644737}, 'kidney 20wk': {'id': '7514_Kidney_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'kidney 20wk', 'full_rpkm': 6.44058, 'exp_rpkm': 6.44, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644738}, 'lung 10wk': {'id': '7514_Lung_10wk_PRJNA270632', 'gene': 7514, 'source_name': 'lung 10wk', 'full_rpkm': 26.2272, 'exp_rpkm': 26.2, 'var': 1.340504, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644739}, 'lung 17wk': {'id': '7514_Lung_17wk_PRJNA270632', 'gene': 7514, 'source_name': 'lung 17wk', 'full_rpkm': 28.7575, 'exp_rpkm': 28.8, 'var': 7.87072, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644740}, 'lung 20wk': {'id': '7514_Lung_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'lung 20wk', 'full_rpkm': 20.0357, 'exp_rpkm': 20.0, 'var': 31.9848, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644741}, 'stomach 10wk': {'id': '7514_Stomach_10wk_PRJNA270632', 'gene': 7514, 'source_name': 'stomach 10wk', 'full_rpkm': 15.9388, 'exp_rpkm': 15.9, 'var': 1.08687, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644742}, 'stomach 16wk': {'id': '7514_Stomach_16wk_PRJNA270632', 'gene': 7514, 'source_name': 'stomach 16wk', 'full_rpkm': 18.7563, 'exp_rpkm': 18.8, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644743}, 'stomach 18wk': {'id': '7514_Stomach_18wk_PRJNA270632', 'gene': 7514, 'source_name': 'stomach 18wk', 'full_rpkm': 18.3787, 'exp_rpkm': 18.4, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644744}, 'stomach 20wk': {'id': '7514_Stomach_20wk_PRJNA270632', 'gene': 7514, 'source_name': 'stomach 20wk', 'full_rpkm': 18.8118, 'exp_rpkm': 18.8, 'var': 4.70739, 'project_desc': 'PRJNA270632', '_version_': 1785734406902644745}};
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"metadata_9606_SAMN03267777", "gene": 7514, "sample_id": "SAMN03267777", "full_rpkm": 6.44058, "exp_rpkm": 6.44, "exp_total": 434400, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 7514, "sample_id": "SAMN03267770", "full_rpkm": 25.0694, "exp_rpkm": 25.1, "exp_total": 979109, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 7514, "sample_id": "SAMN03267767", "full_rpkm": 27.385, "exp_rpkm": 27.4, "exp_total": 939916, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", 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18.7563, "exp_rpkm": 18.8, "exp_total": 765365, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 7514, "sample_id": "SAMN03267771", "full_rpkm": 18.3787, "exp_rpkm": 18.4, "exp_total": 701840, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 7514, "sample_id": "SAMN03267765", "full_rpkm": 20.4531, "exp_rpkm": 20.5, "exp_total": 603140, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 7514, "sample_id": "SAMN03267781", "full_rpkm": 20.2363, 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window.taxId = 9606
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<div>
<select name="p" id="project-selector">
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
</option>
<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
</option>
</select>
<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
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</div>
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<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
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<span class="pubmed-auth-date"> Camus V, <em>et al</em>. Haematologica, 2016 Sep. PMID 27479820, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC5060026/" ref="ordinalpos=0&amp;ncbi_uid=7514&amp;link_uid=PMC5060026">Free PMC Article</a></span></span>
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<span class="pubmed-auth-date"> Zhang X, <em>et al</em>. Microbes Infect, 2006 Mar. PMID 16504563</span>
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<p class="see-all-pm">
<a href="/pubmed?LinkName=gene_pubmed&amp;from_uid=7514" title="See all 620 citations in Pubmed">See all (620) citations in PubMed</a>
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<div class="generif-pubmed generif">
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<div id="gene-popper7" class="gene-rif-popper">Title: Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/37097386" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=37097386">Differential impact of exportin-1-mediated nuclear export of RNAs on the RNA content of extracellular vesicle subpopulations.</a>
<div id="gene-popper8" class="gene-rif-popper">Title: Differential impact of exportin-1-mediated nuclear export of RNAs on the RNA content of extracellular vesicle subpopulations.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/37094850" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=37094850">Interference with XPO1 Suppresses the Stemness and Radioresistance of CD44 Positive Cervical Cancer Cells via Binding with Rad21.</a>
<div id="gene-popper9" class="gene-rif-popper">Title: Interference with XPO1 Suppresses the Stemness and Radioresistance of CD44 Positive Cervical Cancer Cells via Binding with Rad21.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/36200270" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=36200270">Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation.</a>
<div id="gene-popper10" class="gene-rif-popper">Title: Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=7514&amp;sym=XPO1&amp;name=exportin 1&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=7514&amp;symbol=XPO1;task=fixpub">Correction</a>
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&amp;report=generif&amp;term=7514" class="seeall-generif">See all GeneRIFs (225)</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=XPO1[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=7514">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=XPO1[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=7514" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=7514[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=7514[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-HIV-1-interactions">
<section class="rprt-section-header" id="HIV-1-interactions">
<h2 id="header-HIV-1-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div class="fgrid">
<h3 id="replicationinteractions">Replication interactions</h3>
<table summary="replication interactions" class="jig-ncbigrid">
<thead>
<tr>
<th id="hivinter">Interaction</th>
<th id="hivpub">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="hivinter">HIV-1 requires XPO1 for efficient replication as determined through the use of the XPO1 inhibitor KPT-185</td>
<td headers="hivpub">
<a title="PubMed Id(s): 26501108" href="/pubmed/26501108">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivinter">Knockdown of exportin 1 (CRM1 homolog; XPO1) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 18976975" href="/pubmed/18976975">PubMed</a>
</td>
</tr>
</tbody>
</table>
<h3 id="proteininteractions">Protein interactions</h3>
<table summary="protein interactions" class="jig-ncbigrid">
<thead>
<tr>
<th id="hivprotein">Protein</th>
<th id="gene-hivprotein">Gene</th>
<th id="hivinter">Interaction</th>
<th id="hivpub">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="hivprotein">
<a href="/protein/9629360">Pr55(Gag)</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Human CRM1 exports gag mRNA to the cytoplasm more efficiently than rat CRM1 in rat cells, leading to efficient processing of Gag proteins and particle formation</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25275125,22318151,21251165" href="/pubmed/25275125,22318151,21251165">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Mouse-human CRM1 chimera analysis reveals that the amino-acid residues 146-444 of human CRM1 are important for increased HIV-1 titers in mouse cells. Three residues P411/M412/F414 are critical for human CRM1 function</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22933280" href="/pubmed/22933280">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Human CRM1 increases HIV-1 Gag production in mouse cells. Human CRM1 and SRp40 increase the amount of unspliced HIV-1 RNA and have a more-than-additive effect on HIV-1 titers in mouse cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22933280" href="/pubmed/22933280">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Human CRM1 enhances HIV-1 MA-dependent Gag membrane targeting in mouse cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22114565" href="/pubmed/22114565">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Expression of CRM1 enhances Gag production 10-15 fold in rat macrophages, but only marginally in rat T cells. Expression of both CRM1 and CycT1 factors synergistically enhances Gag production to levels approximately 10-40% of those detected in human cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 21251165,19435492" href="/pubmed/21251165,19435492">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">HIV-1 Matrix contains a nuclear export signal (amino acids 15-32) which is recognized by exportin 1 (CRM1; XPO1) and is important for nucleocytoplasmic shuttling of HIV-1 Gag and genomic RNA to the cytoplasm by exportin 1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24478440,22318151,10604476" href="/pubmed/24478440,22318151,10604476">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/9629359">Rev</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">A dimeric CRM1-RanGTP complex binds a Rev-RRE complex to export the Rev-RRE complex from the nuclear to the cytoplasm in cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25723178,25486595" href="/pubmed/25723178,25486595">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Computational molecular docking, alanine scanning, clustering, and evolutionary analysis reveal the interaction of DDX3 with HIV-1 Rev-CRM1-RanGTP complex</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25723178" href="/pubmed/25723178">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Co-immunoprecipitation analysis demonstrates that endogenous RBM14 associates with HIV-1 Rev, XPO1, and p54NRB in cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25589658" href="/pubmed/25589658">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">The CRM1 dimer interface, including residues T346, P411, M412, F414, R474, E478, and H481, facilitates cooperative assembly with the Rev-RRE complex</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25486595" href="/pubmed/25486595">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">CRM1-mediated nuclear export of Rev involves interactions of CRM1 with RanGTP, RanBP1 and RanGEF</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25564443,25486595,25486594,23082981,22783232,19536614,19535902,19149559,19149558,18508616,10518602,10347184,9837918,9111043" href="/pubmed/25564443,25486595,25486594,23082981,22783232,19536614,19535902,19149559,19149558,18508616,10518602,10347184,9837918,9111043">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">CRM1 interacts with the nuclear export signal of Rev and acts as a bridge between Rev and nuclear pore proteins</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25486595,24606219,23754689,23082981,22783232,22675540,22421880,21613532,20953181,19536614,19535902,19342232,19149559,18976462,18508616,9368759" href="/pubmed/25486595,24606219,23754689,23082981,22783232,22675540,22421880,21613532,20953181,19536614,19535902,19342232,19149559,18976462,18508616,9368759">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Nuclear export of Rev is dependent on its activation domain which encodes a nuclear export signal (amino acids 75-83)</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25486595,22783232,20972448,19149559,7745679,7543368" href="/pubmed/25486595,22783232,20972448,19149559,7745679,7543368">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">The addition of a second NES to HIV-1 Rev or a second RRE to Rev-dependent transcripts rescues HIV-1 virion production in murine cells independently of human CRM1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25275125" href="/pubmed/25275125">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">HIV-1 Rev co-localizes with CRM1 at the HIV-1 transcription site in the nucleus</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25275125,24255166" href="/pubmed/25275125,24255166">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Human CRM1 rescues RRE/Rev-dependent HIV-1 virion production in mouse cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25275125,22783232,22114565" href="/pubmed/25275125,22783232,22114565">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Rev recruitment of CRM1 to HIV-1 mRNA is sufficient to mediate nuclear export of incompletely spliced HIV-1 mRNA</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24255166,24158817,23082981,19535902,16354571,11836381" href="/pubmed/24255166,24158817,23082981,19535902,16354571,11836381">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Ratjadone A (myxobacterial metabolite) interacts with CRM1 to inhibit the Rev-dependent HIV-1 RNA nuclear export</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24475978" href="/pubmed/24475978">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Eukaryotic initiation factor 5A (eIF-5A) mediates the binding of CRM1 to Rev</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19149559,19149558,11238447,10381392" href="/pubmed/19149559,19149558,11238447,10381392">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Interaction of CRM1 with nucleoporins Nup42 and Nup159 results in the release of Rev from CRM1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19535902,19149559,10347184" href="/pubmed/19535902,19149559,10347184">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">During Rev-mediated nuclear export of HIV-1 mRNA, Rev interacts directly with the nucleocytoplasmic mRNA-transport system</td>
<td headers="hivpub">
<a title="PubMed Id(s): 21613532,19535902,1648487" href="/pubmed/21613532,19535902,1648487">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Excess CRM1 may downregulate Rev-mediated RNA export by sequestering Rev to a subnucleolar structure</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19020832,10875611" href="/pubmed/19020832,10875611">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Nuclear retention and co-localization of Rev and CRM1 is caused by down-modulation of GAP-associated tyrosine phosphoprotein p62 (Sam68), suggesting Sam68 is directly involved in the CRM1-mediated Rev nuclear export pathway</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19535902,19149559,19149558,12134041" href="/pubmed/19535902,19149559,19149558,12134041">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">HIV-1 Rev interacting protein, exportin 1 (XPO1), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22174317" href="/pubmed/22174317">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">The HEAT repeat helix 9A domain (residues 402-423) of CRM1 serves as an effective cofactor for HIV-1 Rev function in higher primates</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22114565" href="/pubmed/22114565">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Three specific domains (residues 89-123, 405-593, and 594-670) of NF90 promote Rev-RRE mediated nuclear export of Gag mRNA, which is dependent on CRM1 function</td>
<td headers="hivpub">
<a title="PubMed Id(s): 21364984" href="/pubmed/21364984">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">HIV-1 Rev/CRM1 export complexes are observed in nucleoli by cotransfection with CFP/YFP pairs of the proteins on a large three-dimensional set of fixed cells, with Rev/CRM1 colocalization in nucleoli decreasing exponentially after addition of leptomycin B</td>
<td headers="hivpub">
<a title="PubMed Id(s): 15189895" href="/pubmed/15189895">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Studies suggest Rev is necessary and sufficient for the accumulation of incompletely spliced HIV RNAs at nuclear pores while CRM1 is required for translocation across the nuclear pore complex</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22783232,12239324" href="/pubmed/22783232,12239324">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">Rev-Rev interactions (multimerization) are enhanced by CRM1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 20953181,12134013" href="/pubmed/20953181,12134013">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">The C-terminal region of Rev (amino acids 86-116) plays a role in enhancing the interaction of Rev with CRM1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 12134013" href="/pubmed/12134013">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">CRM1 is involved in the binding of Rev to yeast Rip1 and hRip/Rab, which is involved in Rev-mediated nuclear export of HIV-1 mRNA</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19149558,14554087,9368759,9070945,8633082,7637788,7634337" href="/pubmed/19149558,14554087,9368759,9070945,8633082,7637788,7634337">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155908">rev</a>
</td>
<td headers="hivinter">CRM1 interacts with FG-repeat-containing nuclear pore proteins during nuclear export of Rev</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24530126,23754689,22783232,22421880,22355797,21358275,20972448,20712566,20018238,19535902,19149558,19020832,18508616,17661632,16354571,9368759" href="/pubmed/24530126,23754689,22783232,22421880,22355797,21358275,20972448,20712566,20018238,19535902,19149558,19020832,18508616,17661632,16354571,9368759">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/9629358">Tat</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155871">tat</a>
</td>
<td headers="hivinter">Exportin 1 (XPO1, CRM1 homolog) is identified to interact with HIV-1 Tat mutant Nullbasic in HeLa cells by LC MS/MS</td>
<td headers="hivpub">
<a title="PubMed Id(s): 25496916" href="/pubmed/25496916">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155871">tat</a>
</td>
<td headers="hivinter">Interaction of HIV-1 Tat with XPO1 in T-cells is identified by a proteomic strategy based on affinity chromatography</td>
<td headers="hivpub">
<a title="PubMed Id(s): 19454010" href="/pubmed/19454010">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/28872817">Vpr</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155807">vpr</a>
</td>
<td headers="hivinter">Nuclear export of HIV-1 Vpr by exportin-1 is required for efficient HIV replication in tissue macrophages and is important for Vpr incorporation into virions</td>
<td headers="hivpub">
<a title="PubMed Id(s): 20012529,12805458" href="/pubmed/20012529,12805458">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155807">vpr</a>
</td>
<td headers="hivinter">HIV-1 Vpr contains a nuclear export signal within amino acids 1-71 that is sensitive to Leptomycin B, suggesting it is recognized by CRM1 (exportin 1)</td>
<td headers="hivpub">
<a title="PubMed Id(s): 20012529,12805458,11152524" href="/pubmed/20012529,12805458,11152524">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/9629366">Vpu</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155945">vpu</a>
</td>
<td headers="hivinter">HIV-1 Vpu is identified to have a physical interaction with exportin 1 (XPO1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22190034" href="/pubmed/22190034">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/19172948">capsid</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Human CRM1 and SRp40 have a more-than-additive effect on HIV-1 CA production in mouse cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22933280" href="/pubmed/22933280">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein">
<a href="/protein/28876542">matrix</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">Human CRM1 enhances HIV-1 MA-dependent Gag membrane targeting in mouse cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22114565" href="/pubmed/22114565">PubMed</a>
</td>
</tr>
<tr>
<td headers="hivprotein"></td>
<td headers="gene-hivprotein">
<a href="/gene/155030">gag</a>
</td>
<td headers="hivinter">HIV-1 Matrix contains a nuclear export signal (amino acids 15-32) which is recognized by exportin 1 (CRM1; XPO1) and is important for nucleocytoplasmic shuttling of HIV-1 Gag and genomic RNA to the cytoplasm by exportin 1</td>
<td headers="hivpub">
<a title="PubMed Id(s): 10604476" href="/pubmed/10604476">PubMed</a>
</td>
</tr>
</tbody>
</table>
<p class="withnote">
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
</p>
</div>
</div>
</div>
<div class="rprt-section gene-pathways">
<section class="rprt-section-header" id="pathways">
<h2 id="header-pathways">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<ul class="geneinfo-subsec infopathway">
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/7514#section=Pathways&amp;embed=true&amp;hide_all_headings=true&amp;page_size=25" style="border: 0; width: 100%;"></iframe>
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
</ul>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7514/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">GDB:434012 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=157204%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=157204">UniSTS:157204</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">D11S2560 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=37928%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=37928">UniSTS:37928</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">L17705 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=66091%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=66091">UniSTS:66091</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">D8S2279 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=473907%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=473907">UniSTS:473907</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH75489 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=84533%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=84533">UniSTS:84533</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">sY3084 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=515126%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=515126">UniSTS:515126</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH46337 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=53817%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=53817">UniSTS:53817</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">L18426 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=34648%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=34648">UniSTS:34648</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">D1S1423 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=149619%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=149619">UniSTS:149619</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH80312 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=89486%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=89486">UniSTS:89486</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH12025 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=36347%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=36347">UniSTS:36347</a></li></ul></li>
</ul>
</div>
</div>
<div></div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/7514/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="infosec info-comment" id="info-comment">
<h3 id="CloneNames">
<a class="jig-ncbitoggler-open">Clone Names</a>
</h3>
<ul class="geneinfo-subsec">
<li>DKFZp686B1823 </li>
</ul>
</div>
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003723">enables RNA binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005049">enables nuclear export signal receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005049">enables nuclear export signal receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-3-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/29666234" target="_blank" title="PubMed ID 29666234" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=29666234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005049">enables nuclear export signal receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-4-0" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12724356,12773398" target="_blank" title="PubMed ID 12724356,12773398" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12724356,12773398">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005049">enables nuclear export signal receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-5-0" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/31340148" target="_blank" title="PubMed ID 31340148" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=31340148">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005049">enables nuclear export signal receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-6-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-7-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/10358091,10557333,11000203,11545741,11932251,12724356,15161933,16302269,16314522,16319068,17099693,17268548,18952844,19339969,19339972,19955415,20485264,20826784,20921223,21378169,22022502,22084111,22250199,22427340,22500989,22730302,23850451,24169621,25893289,26496610,29666234,30131165,31575075,35271311,35384245" target="_blank" title="PubMed ID 10358091,10557333,11000203,11545741,11932251,12724356,15161933,16302269,16314522,16319068,17099693,17268548,18952844,19339969,19339972,19955415,20485264,20826784,20921223,21378169,22022502,22084111,22250199,22427340,22500989,22730302,23850451,24169621,25893289,26496610,29666234,30131165,31575075,35271311,35384245" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=10358091,10557333,11000203,11545741,11932251,12724356,15161933,16302269,16314522,16319068,17099693,17268548,18952844,19339969,19339972,19955415,20485264,20826784,20921223,21378169,22022502,22084111,22250199,22427340,22500989,22730302,23850451,24169621,25893289,26496610,29666234,30131165,31575075,35271311,35384245">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031267">enables small GTPase binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-8-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006406">involved_in mRNA export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/31340148" target="_blank" title="PubMed ID 31340148" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=31340148">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006913">involved_in nucleocytoplasmic transport</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-2-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/11000203" target="_blank" title="PubMed ID 11000203" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=11000203">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006611">involved_in protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
<div id="evidence-code-3-1" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/21378169" target="_blank" title="PubMed ID 21378169" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=21378169">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006611">involved_in protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-4-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22250199,29666234" target="_blank" title="PubMed ID 22250199,29666234" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=22250199,29666234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006611">acts_upstream_of_or_within protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-5-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22427340" target="_blank" title="PubMed ID 22427340" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=22427340">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006611">involved_in protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-6-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/12773398" target="_blank" title="PubMed ID 12773398" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12773398">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006611">involved_in protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-7-1" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/29666234" target="_blank" title="PubMed ID 29666234" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=29666234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0034504">involved_in protein localization to nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-8-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010824">involved_in regulation of centrosome duplication</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-9-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032434">involved_in regulation of proteasomal ubiquitin-dependent protein catabolic process</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-10-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/29666234" target="_blank" title="PubMed ID 29666234" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=29666234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046825">involved_in regulation of protein export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-11-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000055">involved_in ribosomal large subunit export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-12-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000055">involved_in ribosomal large subunit export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-13-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/12773398" target="_blank" title="PubMed ID 12773398" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12773398">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000056">involved_in ribosomal small subunit export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-14-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000056">involved_in ribosomal small subunit export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-15-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/12773398" target="_blank" title="PubMed ID 12773398" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12773398">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000054">involved_in ribosomal subunit export from nucleus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-16-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/12724356" target="_blank" title="PubMed ID 12724356" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12724356">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0042254">involved_in ribosome biogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-17-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/12724356" target="_blank" title="PubMed ID 12724356" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12724356">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0015030">located_in Cajal body</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005642">located_in annulate lamellae</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/12210765" target="_blank" title="PubMed ID 12210765" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=12210765">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">is_active_in cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-3-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">located_in cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-4-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23782956" target="_blank" title="PubMed ID 23782956" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=23782956">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-5-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-6-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043231">located_in intracellular membrane-bounded organelle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-7-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000776">located_in kinetochore</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-8-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/17363900" target="_blank" title="PubMed ID 17363900" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=17363900">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016020">located_in membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
<div id="evidence-code-9-2" class="ecode">
<br />
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
</div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/19946888" target="_blank" title="PubMed ID 19946888" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=19946888">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005635">located_in nuclear envelope</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-10-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/9368044" target="_blank" title="PubMed ID 9368044" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=9368044">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031965">located_in nuclear membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-11-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005730">located_in nucleolus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-12-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23782956" target="_blank" title="PubMed ID 23782956" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=23782956">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-13-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-14-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">is_active_in nucleus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-15-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032991">part_of protein-containing complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-16-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/10557333,29666234" target="_blank" title="PubMed ID 10557333,29666234" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=10557333,29666234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:1990904">part_of ribonucleoprotein complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-17-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/18809582" target="_blank" title="PubMed ID 18809582" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=18809582">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>exportin-1</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>chromosome region maintenance 1 homolog</dd>
<dd>chromosome region maintenance 1 protein homolog</dd>
<dd>exportin 1 (CRM1 homolog, yeast)</dd>
<dd>exportin-1 (required for chromosome region maintenance)</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
<span class="new-icon">NEW</span>
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=7514&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="mrnaandproteins-p174407904">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_001410799.1">NM_001410799.1</a><a href="/protein/NP_001397728.1">NP_001397728.1</a>  exportin-1 isoform 2</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AC016727">AC016727</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS92765.1">CCDS92765.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000502940.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000502940.1</a>, <a href="http://www.ensembl.org/id/ENST00000676999.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000676999.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_003400.4">NM_003400.4</a><a href="/protein/NP_003391.1">NP_003391.1</a>  exportin-1 isoform 1</p>
<p>
<a href="/ipg/NP_003391.1/" ref="ncbi_uid=7514">See identical proteins and their annotated locations for NP_003391.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AC016727, AK124769, AL833550, BC032847, BX492941, BX643790, BX647758, BX954288, CR749840, Y08614">AC016727, AK124769, AL833550, BC032847, BX492941, BX643790, BX647758, BX954288, CR749840, Y08614</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS33205.1">CCDS33205.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000384863.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000384863.2</a>, <a href="http://www.ensembl.org/id/ENST00000401558.7" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000401558.7</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_003391.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">1044</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p186341936">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p186341936">Genomic </h4>
<ol>
<li>
<p>NC_000002.12 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>61477849..61538612 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000002.12?from=61477849&amp;to=61538612&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12?from=61477849&amp;to=61538612&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_000002.12?from=61477849&amp;to=61538612&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12?from=61477849&amp;to=61538612&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_000002.12?from=61468734&amp;to=61547725&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_000002.12?from=61468734&amp;to=61547725&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p161695808">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_047445764.1">XM_047445764.1</a><a href="/protein/XP_047301720.1">XP_047301720.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000503808.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000503808.1</a>, <a href="http://www.ensembl.org/id/ENST00000676771.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000676771.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011533097.2">XM_011533097.2</a><a href="/protein/XP_011531399.1">XP_011531399.1</a>  exportin-1 isoform X1</p>
<p>
<a href="/ipg/XP_011531399.1/" ref="ncbi_uid=7514">See identical proteins and their annotated locations for XP_011531399.1</a>
</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000504247.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000504247.1</a>, <a href="http://www.ensembl.org/id/ENST00000676553.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000676553.1</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011531399.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">1044</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445771.1">XM_047445771.1</a><a href="/protein/XP_047301727.1">XP_047301727.1</a>  exportin-1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_005264544.3">XM_005264544.3</a><a href="/protein/XP_005264601.1">XP_005264601.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005264601.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">1029</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011533098.3">XM_011533098.3</a><a href="/protein/XP_011531400.1">XP_011531400.1</a>  exportin-1 isoform X3</p>
<p>
<a href="/ipg/XP_011531400.1/" ref="ncbi_uid=7514">See identical proteins and their annotated locations for XP_011531400.1</a>
</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000503194.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000503194.1</a>, <a href="http://www.ensembl.org/id/ENST00000678081.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000678081.1</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011531400.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">999</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445761.1">XM_047445761.1</a><a href="/protein/XP_047301717.1">XP_047301717.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445767.1">XM_047445767.1</a><a href="/protein/XP_047301723.1">XP_047301723.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_047301723.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">999</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445760.1">XM_047445760.1</a><a href="/protein/XP_047301716.1">XP_047301716.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000504087.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000504087.1</a>, <a href="http://www.ensembl.org/id/ENST00000677239.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000677239.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445765.1">XM_047445765.1</a><a href="/protein/XP_047301721.1">XP_047301721.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445759.1">XM_047445759.1</a><a href="/protein/XP_047301715.1">XP_047301715.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445762.1">XM_047445762.1</a><a href="/protein/XP_047301718.1">XP_047301718.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445768.1">XM_047445768.1</a><a href="/protein/XP_047301724.1">XP_047301724.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_047301724.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">999</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_006712094.4">XM_006712094.4</a><a href="/protein/XP_006712157.1">XP_006712157.1</a>  exportin-1 isoform X1</p>
<p>
<a href="/ipg/XP_006712157.1/" ref="ncbi_uid=7514">See identical proteins and their annotated locations for XP_006712157.1</a>
</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000503167.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000503167.1</a>, <a href="http://www.ensembl.org/id/ENST00000677150.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000677150.1</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_006712157.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">1044</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445763.1">XM_047445763.1</a><a href="/protein/XP_047301719.1">XP_047301719.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445769.1">XM_047445769.1</a><a href="/protein/XP_047301725.1">XP_047301725.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_047301725.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">999</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445758.1">XM_047445758.1</a><a href="/protein/XP_047301714.1">XP_047301714.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_024453125.2">XM_024453125.2</a><a href="/protein/XP_024308893.1">XP_024308893.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000385942.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000385942.2</a>, <a href="http://www.ensembl.org/id/ENST00000404992.6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000404992.6</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308893.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">15</span><span class="cddto">1044</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445766.1">XM_047445766.1</a><a href="/protein/XP_047301722.1">XP_047301722.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_024453127.2">XM_024453127.2</a><a href="/protein/XP_024308895.1">XP_024308895.1</a>  exportin-1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_024308895.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">913</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445772.1">XM_047445772.1</a><a href="/protein/XP_047301728.1">XP_047301728.1</a>  exportin-1 isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000503702.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000503702.1</a>, <a href="http://www.ensembl.org/id/ENST00000677803.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000677803.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_005264546.3">XM_005264546.3</a><a href="/protein/XP_005264603.1">XP_005264603.1</a>  exportin-1 isoform X6</p>
<p>
<a href="/ipg/XP_005264603.1/" ref="ncbi_uid=7514">See identical proteins and their annotated locations for XP_005264603.1</a>
</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000504749.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000504749.1</a>, <a href="http://www.ensembl.org/id/ENST00000677556.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000677556.1</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005264603.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227432">COG5101</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">913</span></dt>
<dd class="clearfix"> CRM1; Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047445773.1">XM_047445773.1</a><a href="/protein/XP_047301729.1">XP_047301729.1</a>  exportin-1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000503789.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENSP00000503789.1</a>, <a href="http://www.ensembl.org/id/ENST00000677476.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">ENST00000677476.1</a></dd>
</dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p233557872">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p233557872">Genomic </h4>
<ol>
<li>
<p>NC_060926.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>61483936..61544825 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060926.1?from=61483936&amp;to=61544825&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_060926.1?from=61483936&amp;to=61544825&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_060926.1?from=61483936&amp;to=61544825&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_060926.1?from=61483936&amp;to=61544825&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_060926.1?from=61474802&amp;to=61553957&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=NC_060926.1?from=61474802&amp;to=61553957&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p185203904">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054343778.1">XM_054343778.1</a><a href="/protein/XP_054199753.1">XP_054199753.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343783.1">XM_054343783.1</a><a href="/protein/XP_054199758.1">XP_054199758.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343790.1">XM_054343790.1</a><a href="/protein/XP_054199765.1">XP_054199765.1</a>  exportin-1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343779.1">XM_054343779.1</a><a href="/protein/XP_054199754.1">XP_054199754.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343786.1">XM_054343786.1</a><a href="/protein/XP_054199761.1">XP_054199761.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343780.1">XM_054343780.1</a><a href="/protein/XP_054199755.1">XP_054199755.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343787.1">XM_054343787.1</a><a href="/protein/XP_054199762.1">XP_054199762.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343777.1">XM_054343777.1</a><a href="/protein/XP_054199752.1">XP_054199752.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343784.1">XM_054343784.1</a><a href="/protein/XP_054199759.1">XP_054199759.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343776.1">XM_054343776.1</a><a href="/protein/XP_054199751.1">XP_054199751.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343781.1">XM_054343781.1</a><a href="/protein/XP_054199756.1">XP_054199756.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343788.1">XM_054343788.1</a><a href="/protein/XP_054199763.1">XP_054199763.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343775.1">XM_054343775.1</a><a href="/protein/XP_054199750.1">XP_054199750.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343782.1">XM_054343782.1</a><a href="/protein/XP_054199757.1">XP_054199757.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343789.1">XM_054343789.1</a><a href="/protein/XP_054199764.1">XP_054199764.1</a>  exportin-1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2Y6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2Y6</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343774.1">XM_054343774.1</a><a href="/protein/XP_054199749.1">XP_054199749.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343773.1">XM_054343773.1</a><a href="/protein/XP_054199748.1">XP_054199748.1</a>  exportin-1 isoform X1</p>
<dl>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/A6NL14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A6NL14</a>, <a href="https://www.uniprot.org/uniprot/A8K1K5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A8K1K5</a>, <a href="https://www.uniprot.org/uniprot/D6W5E2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">D6W5E2</a>, <a href="https://www.uniprot.org/uniprot/O14980" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">O14980</a>, <a href="https://www.uniprot.org/uniprot/Q63HP8" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q63HP8</a>, <a href="https://www.uniprot.org/uniprot/Q68CP3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q68CP3</a>, <a href="https://www.uniprot.org/uniprot/Q99433" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">Q99433</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343785.1">XM_054343785.1</a><a href="/protein/XP_054199760.1">XP_054199760.1</a>  exportin-1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V2H0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V2H0</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V461" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V461</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343792.1">XM_054343792.1</a><a href="/protein/XP_054199767.1">XP_054199767.1</a>  exportin-1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343791.1">XM_054343791.1</a><a href="/protein/XP_054199766.1">XP_054199766.1</a>  exportin-1 isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A7I2V3W6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V3W6</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343793.1">XM_054343793.1</a><a href="/protein/XP_054199768.1">XP_054199768.1</a>  exportin-1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054343794.1">XM_054343794.1</a><a href="/protein/XP_054199769.1">XP_054199769.1</a>  exportin-1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A7I2V488" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V488</a>, <a href="https://www.uniprot.org/uniprot/A0A7I2V6B9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7514&amp;nlmid=&amp;db=gene">A0A7I2V6B9</a></dd>
</dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7514/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">O14980.1</td>
<td headers="rs-link rs-genepept">
<a href="/protein/68052989" ref="ordinalpos=1&amp;ncbi_uid=7514&amp;link_uid=68052989">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/O14980">UniProtKB/Swiss-Prot:O14980</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/XPO1?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>XPO1 products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000082898" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>XPO1 gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/7514/" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (795 hits/1433 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
<ul>
<li>
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7642">
<span>XPO1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=XPO1_1" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>XPO1_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/O14980" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
<ul>
<li>
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=3014" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8191">
<span>exportin 1 gene</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&amp;modeInput=Absolute&amp;primaryGene=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&amp;modeInput=Absolute&amp;primaryGene=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D7514%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=20060" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=53335" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000082898" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN62871/" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN62878/" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN62889/" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Pharmacogenomics Knowledge Base</li>
<ul>
<li>
<a target="_blank" href="https://www.pharmgkb.org/gene/PA37418" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4067">
<span>Annotated Pharmacogenomic Information for XPO1 [PharmGKB]</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Gene Wiki</li>
<ul>
<li>
<a target="_blank" href="https://en.wikipedia.org/wiki/XPO1" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=6933">
<span>The Gene Wiki</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=XPO1" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for XPO1</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/crm1/proteins-enzymes?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=proteins" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>CRM1 Proteins</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/crm1/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>CRM1 Antibodies</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/XPO1-antibody.html" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.labome.com/review/gene/human/XPO1-antibody.html" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagent review</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&amp;field=5&amp;key=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order shRNA clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&amp;field=5&amp;prt=16&amp;key=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order miRNA target clones</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneTex Inc</li>
<ul>
<li>
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=7514&amp;type=01&amp;page=1" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8117">
<span>Find Quality Antibodies</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
<ul>
<li>
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=XPO1;" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3267">
<span>Kazusa DNA Research Institute</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=Emb" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order Emb cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.origene.com/search?q=Xpo1" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order Xpo1 cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=7514" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open">
<span>Miscellaneous</span>
</a>
<ul>
<li><span class="free-rsc"></span>Reactome</li>
<ul>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-1643685" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Disease</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-8953854" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Metabolism of RNA</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-162582" ref="itool=Gene_FullReport&amp;uid=7514&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Signal Transduction</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
<div id="urls-in-genombrowser" style="display:none">
</div>
</div>
</div>
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</div>
<div class=" bottom">
</div>
</div>
</div>
<div class="supplemental col three_col last" id="sidebar_tabular">
<!-- sidebar close/hide button-->
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#HIV-1-interactions">HIV-1 interactions</a>
</li>
<li class="">
<a href="#pathways">Pathways from PubChem</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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<li>
<a href="#">Loading...</a>
</li>
</ul>
</div>
</div>
<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/7514" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&amp;from_uid=7514" ref="log$=recordlinks">3D structures</a>
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=7514" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=7514" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=7514" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai_active&amp;from_uid=7514" ref="log$=recordlinks">BioAssays, RNAi Target, Active</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent, which is identified as a hit in a RNAi screening and flagged as "active" in the corresponding BioAssay record</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=7514" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=7514" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=7514" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=7514" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=7514" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=7514" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=7514" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=7514" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=7514" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&amp;from_uid=7514" ref="log$=recordlinks">GAP</a>
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=7514" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&amp;from_uid=7514" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=7514" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=7514" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=7514[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=7514" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=7514" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=7514" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=7514" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=7514" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=7514" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=7514" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=7514" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=7514" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=7514" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=7514" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=7514" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=7514" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&amp;from_uid=7514" ref="log$=recordlinks">Related gene-specific medical variations</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=7514" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=7514" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=7514[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
<div class="portlet dis-links-to-other-res brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Links to other resources</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12825">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000082898">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:12825">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=7514">AceView</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_003400">UCSC</a>
</li>
<li>
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&amp;LIST=BC032847">MGC</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:7514">KEGG</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-general-info">
<div class="portlet_head">
<div class="portlet_title">
<h3>General information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
</li>
<li>
<a href="/books/NBK3840">FAQ</a>
</li>
<li>
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
</li>
<li>
<a href="/books/NBK3841/">Help</a>
</li>
<li>
<a href="/books/NBK3842/">My NCBI help</a>
</li>
<li>
<a href="/books/NBK21085/">NCBI Handbook</a>
</li>
<li>
<a href="/gene/statistics/">Statistics</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-related-sites">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related sites</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-feedback">
<div class="portlet_head">
<div class="portlet_title">
<h3>Feedback</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&amp;deptID=28049">Contact Help Desk</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=7514&amp;symbol=XPO1">Submit Correction</a>
</li>
<li>
<a href="/gene/submit-generif?geneId=7514&amp;sym=XPO1&amp;name=exportin 1&amp;org=Homo sapiens">Submit GeneRIF</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-subscription">
<div class="portlet_head">
<div class="portlet_title">
<h3>Subscription</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
</li>
</ul>
</div>
</div>
</div>
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
<div class="portlet">
<div class="portlet_head">
<div class="portlet_title">
<h3>Recent activity</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
Clear
</a>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&amp;" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67ca0014a68b6b5afc240ec1">XPO1 exportin 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">XPO1 exportin 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:7514</div></div>
<div class="tertiary">Gene</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67ca0012b15b832ebcc2a24b">exportin-1 isoform 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">exportin-1 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|4507943|ref|NP_003391.1|</div></div>
<div class="tertiary">Protein</div>
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<div class="ralinkpop offscreen_noflow">WRNIP1 WRN helicase interacting protein 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:56897</div></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67ca000cb15b832ebcc281c8">ATPase WRNIP1 isoform 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">ATPase WRNIP1 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|18426902|ref|NP_064520.2|</div></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67ca000ab15b832ebcc27747">bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [Homo sapiens]<div class="brieflinkpopdesc">gi|110735439|ref|NP_000544.2|</div></div>
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