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2929 lines
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240 KiB
XML
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'3531',linkname:'',idsfromresult:'3635',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9e00069195c35ad6daf6c" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="3531" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
||
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|
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</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
||
|
||
|
||
</div>
|
||
<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">INPP5D</span> inositol polyphosphate-5-phosphatase D [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 3635, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
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<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
||
<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
||
<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="INPP5D_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="3635" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">INPP5D<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>inositol polyphosphate-5-phosphatase D<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6079" data-gblink-text="Ensembl">HGNC:HGNC:6079</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000168918" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000168918">Ensembl:ENSG00000168918</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/601582" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=3635&link_uid=601582">MIM:601582;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:6079" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=3635&link_uid=HGNC:6079">AllianceGenome:HGNC:6079</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=3635&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>SHIP; SHIP1; SHIP-1; hp51CN; SIP-145; p150Ship</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Deficiencies in the encoded protein, SHIP1, have been associated with Inflammatory Bowel Disease types such as Crohn's Disease and Ulcerative Colitis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2020]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Broad expression in lymph node (RPKM 33.2), spleen (RPKM 31.1) and 21 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/16331">mouse</a>
|
||
<a href="/gene/3635/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/3635/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/3635/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See INPP5D in </span><a href="/genome/gdv/?context=gene&acc=3635" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">2q37.1</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>27</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=3635&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.12 (233060342..233207903) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=3635&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_060926.1 (233547692..233695995) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=3635&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.11 (233925052..234116549) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 2 - NC_000002.12</strong><img usemap="#nbrMap3635_568815596" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=3635&nuc_gi=568815596&n0=NGEF&n1=LOC101928881&n2=NEU2&n3=LOC129935872&n4=LOC129935873&n5=INPP5D&n6=LOC129935874&n7=LOC129935875&n8=LOC127276062&n9=LOC127276063&n10=LOC129935876&n11=LOC129935877&n12=LOC127276064&n13=LOC129935878&n14=LOC129935879&n15=LOC122861316&n16=LOC129935880&n17=LOC127276065&n18=LOC127276066&n19=LOC127276067&n20=LOC129935881&n21=LOC127276068&n22=LOC127276069&n23=LOC127276070&n24=LOC127276071&n25=LOC127276072&n26=LOC127276073&n27=RN7SL32P&n28=LOC127276074&n29=LOC129660916&n30=LOC129660917&n31=LOC126806555&n32=LOC129935882&n33=ATG16L1&n34=LOC129935883&n35=LOC129935884&n36=LOC129935885&n37=SCARNA5&n38=SCARNA6&n39=LOC127276075" /><map name="nbrMap3635_568815596" id="nbrMap3635_568815596">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'neuronal guanine nucleotide exchange factor')" onMouseOut="hidetip()" coords="42,23,180,31" alt="Neighboring gene neuronal guanine nucleotide exchange factor" href="/gene/25791" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC101928881')" onMouseOut="hidetip()" coords="117,35,187,43" alt="Neighboring gene uncharacterized LOC101928881" href="/gene/101928881" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12465')" onMouseOut="hidetip()" coords="153,47,223,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12465" href="/gene/129935872" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17328')" onMouseOut="hidetip()" coords="158,59,228,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17328" href="/gene/129935873" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12466')" onMouseOut="hidetip()" coords="159,71,229,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12466" href="/gene/129935874" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17329')" onMouseOut="hidetip()" coords="159,83,229,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17329" href="/gene/129935875" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233926783-233927376')" onMouseOut="hidetip()" coords="160,95,230,103" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233926783-233927376" href="/gene/127276062" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233927377-233927970')" onMouseOut="hidetip()" coords="160,107,230,115" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233927377-233927970" href="/gene/127276063" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17330')" onMouseOut="hidetip()" coords="161,119,231,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17330" href="/gene/129935876" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12468')" onMouseOut="hidetip()" coords="166,131,236,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12468" href="/gene/129935877" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233937995-233938700')" onMouseOut="hidetip()" coords="170,143,240,151" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233937995-233938700" href="/gene/127276064" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'neuraminidase 2')" onMouseOut="hidetip()" coords="175,155,205,163" alt="Neighboring gene neuraminidase 2" href="/gene/4759" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17331')" onMouseOut="hidetip()" coords="177,167,247,175" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17331" href="/gene/129935878" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17332')" onMouseOut="hidetip()" coords="177,179,247,187" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17332" href="/gene/129935879" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 10619')" onMouseOut="hidetip()" coords="179,191,249,199" alt="Neighboring gene Sharpr-MPRA regulatory region 10619" href="/gene/122861316" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17333')" onMouseOut="hidetip()" coords="179,203,249,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17333" href="/gene/129935880" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233953501-233954000')" onMouseOut="hidetip()" coords="183,23,253,31" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233953501-233954000" href="/gene/127276065" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233972121-233972622')" onMouseOut="hidetip()" coords="199,215,269,223" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233972121-233972622" href="/gene/127276066" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233972623-233973122')" onMouseOut="hidetip()" coords="199,227,269,235" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233972623-233973122" href="/gene/127276067" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17334')" onMouseOut="hidetip()" coords="200,239,270,247" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17334" href="/gene/129935881" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233982267-233982860')" onMouseOut="hidetip()" coords="208,155,278,163" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233982267-233982860" href="/gene/127276068" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr2:233987251-233987751')" onMouseOut="hidetip()" coords="212,251,282,259" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:233987251-233987751" href="/gene/127276069" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233988888-233989435')" onMouseOut="hidetip()" coords="213,263,283,271" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233988888-233989435" href="/gene/127276070" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233989436-233989982')" onMouseOut="hidetip()" coords="214,275,284,283" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:233989436-233989982" href="/gene/127276071" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:233993677-233994176')" onMouseOut="hidetip()" coords="217,287,287,295" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:233993677-233994176" href="/gene/127276072" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:234072305-234072918')" onMouseOut="hidetip()" coords="247,47,317,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:234072305-234072918" href="/gene/127276073" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr2:234125377-234125936')" onMouseOut="hidetip()" coords="293,23,363,31" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr2:234125377-234125936" href="/gene/127276074" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:234131944-234132095')" onMouseOut="hidetip()" coords="299,59,369,67" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:234131944-234132095" href="/gene/129660916" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'RNA, 7SL, cytoplasmic 32, pseudogene')" onMouseOut="hidetip()" coords="303,71,353,79" alt="Neighboring gene RNA, 7SL, cytoplasmic 32, pseudogene" href="/gene/106480930" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:234151441-234151635')" onMouseOut="hidetip()" coords="315,83,385,91" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:234151441-234151635" href="/gene/129660917" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:234155927-234157126')" onMouseOut="hidetip()" coords="319,47,389,55" alt="Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:234155927-234157126" href="/gene/126806555" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17335')" onMouseOut="hidetip()" coords="323,95,393,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17335" href="/gene/129935882" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17336')" onMouseOut="hidetip()" coords="332,107,402,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17336" href="/gene/129935883" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17337')" onMouseOut="hidetip()" coords="332,119,402,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17337" href="/gene/129935884" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12469')" onMouseOut="hidetip()" coords="335,131,405,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12469" href="/gene/129935885" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'autophagy related 16 like 1')" onMouseOut="hidetip()" coords="348,35,423,43" alt="Neighboring gene autophagy related 16 like 1" href="/gene/55054" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr2:234197330-234197831')" onMouseOut="hidetip()" coords="353,143,423,151" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr2:234197330-234197831" href="/gene/127276075" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'small Cajal body-specific RNA 5')" onMouseOut="hidetip()" coords="369,23,414,31" alt="Neighboring gene small Cajal body-specific RNA 5" href="/gene/677775" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'small Cajal body-specific RNA 6')" onMouseOut="hidetip()" coords="378,59,423,67" alt="Neighboring gene small Cajal body-specific RNA 6" href="/gene/677772" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="3635">
|
||
<option value="NC_000002.12_233060341_233207902">NC_000002.12 Chromosome 2 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NW_011332690.1_5679_153240">NW_011332690.1 Chromosome 2 Reference GRCh38.p14 PATCHES</option>
|
||
<option value="NG_033988.1_5375_152936">NG_033988.1 RefSeqGene</option>
|
||
<option value="NC_060926.1_233547691_233695994">NC_060926.1 Chromosome 2 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000002.11_233925051_234116548">NC_000002.11 Chromosome 2 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000002" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&from=233038207&to=233230036&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&from=233060342&to=233207903" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&from=233060342&to=233207903" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000002" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=233038207&to=233230036&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=233038207&to=233230036&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.12" sid="1" type="hidden" id="nucleotideLink_NC_000002_12_233060341_233207902" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&amp;from=233038207&amp;to=233230036&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.12">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&amp;from=233060342&amp;to=233207903" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.12">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&amp;from=233060342&amp;to=233207903" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.12">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.12" sid="1" type="hidden" id="relString_NC_000002_12_233060341_233207902" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.12&amp;from=233038207&amp;to=233230036&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NW_011332690.1" sid="1" type="hidden" id="nucleotideLink_NW_011332690_1_5679_153240" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NW_011332690.1?report=graph&amp;from=1&amp;to=175374&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NW_011332690.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NW_011332690.1?report=fasta&amp;from=5680&amp;to=153241" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NW_011332690.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NW_011332690.1?report=genbank&amp;from=5680&amp;to=153241" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NW_011332690.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NW_011332690.1" sid="1" type="hidden" id="relString_NW_011332690_1_5679_153240" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NW_011332690.1&amp;from=1&amp;to=175374&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_033988.1" sid="1" type="hidden" id="nucleotideLink_NG_033988_1_5375_152936" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_033988.1?report=graph&amp;from=1&amp;to=175070&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NG_033988.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_033988.1?report=fasta&amp;from=5376&amp;to=152937" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NG_033988.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_033988.1?report=genbank&amp;from=5376&amp;to=152937" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NG_033988.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_033988.1" sid="1" type="hidden" id="relString_NG_033988_1_5375_152936" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_033988.1&amp;from=1&amp;to=175070&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060926.1" sid="1" type="hidden" id="nucleotideLink_NC_060926_1_233547691_233695994" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060926.1?report=graph&amp;from=233525446&amp;to=233718239&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_060926.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060926.1?report=fasta&amp;from=233547692&amp;to=233695995" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_060926.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060926.1?report=genbank&amp;from=233547692&amp;to=233695995" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_060926.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060926.1" sid="1" type="hidden" id="relString_NC_060926_1_233547691_233695994" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060926.1&amp;from=233525446&amp;to=233718239&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.11" sid="1" type="hidden" id="nucleotideLink_NC_000002_11_233925051_234116548" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.11?report=graph&amp;from=233896326&amp;to=234145273&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.11">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.11?report=fasta&amp;from=233925052&amp;to=234116549" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.11">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.11?report=genbank&amp;from=233925052&amp;to=234116549" ref="ordinalpos=1&amp;ncbi_uid=3635&amp;link_uid=NC_000002.11">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.11" sid="1" type="hidden" id="relString_NC_000002_11_233925051_234116548" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.11&amp;from=233896326&amp;to=234145273&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/3635/?report=expression" data-url="/gene/3635/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/3635" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '3635_Adrenal_10wk_PRJNA270632', 'gene': 3635, 'source_name': 'adrenal 10wk', 'full_rpkm': 0.498265, 'exp_rpkm': 0.498, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396545859626}, 'adrenal 16wk': {'id': '3635_Adrenal_16wk_PRJNA270632', 'gene': 3635, 'source_name': 'adrenal 16wk', 'full_rpkm': 0.369159, 'exp_rpkm': 0.369, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396545859627}, 'adrenal 18wk': {'id': '3635_Adrenal_18wk_PRJNA270632', 'gene': 3635, 'source_name': 'adrenal 18wk', 'full_rpkm': 0.466557, 'exp_rpkm': 0.467, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396545859628}, 'adrenal 20wk': {'id': '3635_Adrenal_20wk_PRJNA270632', 'gene': 3635, 'source_name': 'adrenal 20wk', 'full_rpkm': 0.568024, 'exp_rpkm': 0.568, 'var': 0.00419036, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908160}, 'heart 10wk': {'id': '3635_Heart_10wk;_PRJNA270632', 'gene': 3635, 'source_name': 'heart 10wk', 'full_rpkm': 0.239034, 'exp_rpkm': 0.239, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908161}, 'heart 11wk': {'id': '3635_Heart_11wk;_PRJNA270632', 'gene': 3635, 'source_name': 'heart 11wk', 'full_rpkm': 0.374689, 'exp_rpkm': 0.375, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908162}, 'heart 17wk': {'id': '3635_Heart_17wk;_PRJNA270632', 'gene': 3635, 'source_name': 'heart 17wk', 'full_rpkm': 0.279927, 'exp_rpkm': 0.28, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908163}, 'heart 18wk': {'id': '3635_Heart_18wk;_PRJNA270632', 'gene': 3635, 'source_name': 'heart 18wk', 'full_rpkm': 0.413874, 'exp_rpkm': 0.414, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908164}, 'heart 20wk': {'id': '3635_Heart_20wk_PRJNA270632', 'gene': 3635, 'source_name': 'heart 20wk', 'full_rpkm': 0.233754, 'exp_rpkm': 0.234, 'var': 0.00874134, 'project_desc': 'PRJNA270632', '_version_': 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'gene': 3635, 'source_name': 'intestine 20wk', 'full_rpkm': 1.16011, 'exp_rpkm': 1.16, 'var': 0.132125, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908170}, 'kidney 10wk': {'id': '3635_Kidney_10wk_PRJNA270632', 'gene': 3635, 'source_name': 'kidney 10wk', 'full_rpkm': 0.184987, 'exp_rpkm': 0.185, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908171}, 'kidney 16wk': {'id': '3635_Kidney_16wk_PRJNA270632', 'gene': 3635, 'source_name': 'kidney 16wk', 'full_rpkm': 0.244807, 'exp_rpkm': 0.245, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908172}, 'kidney 20wk': {'id': '3635_Kidney_20wk_PRJNA270632', 'gene': 3635, 'source_name': 'kidney 20wk', 'full_rpkm': 0.0743625, 'exp_rpkm': 0.0744, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908173}, 'lung 10wk': {'id': '3635_Lung_10wk_PRJNA270632', 'gene': 3635, 'source_name': 'lung 10wk', 'full_rpkm': 0.497371, 'exp_rpkm': 0.497, 'var': 0.00233912, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908174}, 'lung 17wk': {'id': '3635_Lung_17wk_PRJNA270632', 'gene': 3635, 'source_name': 'lung 17wk', 'full_rpkm': 0.861979, 'exp_rpkm': 0.862, 'var': 0.00203386, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908175}, 'lung 20wk': {'id': '3635_Lung_20wk_PRJNA270632', 'gene': 3635, 'source_name': 'lung 20wk', 'full_rpkm': 0.717325, 'exp_rpkm': 0.717, 'var': 0.0026252, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908176}, 'stomach 10wk': {'id': '3635_Stomach_10wk_PRJNA270632', 'gene': 3635, 'source_name': 'stomach 10wk', 'full_rpkm': 0.525521, 'exp_rpkm': 0.526, 'var': 0.0508336, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908177}, 'stomach 16wk': {'id': '3635_Stomach_16wk_PRJNA270632', 'gene': 3635, 'source_name': 'stomach 16wk', 'full_rpkm': 0.735681, 'exp_rpkm': 0.736, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908178}, 'stomach 18wk': {'id': '3635_Stomach_18wk_PRJNA270632', 'gene': 3635, 'source_name': 'stomach 18wk', 'full_rpkm': 0.935003, 'exp_rpkm': 0.935, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908179}, 'stomach 20wk': {'id': '3635_Stomach_20wk_PRJNA270632', 'gene': 3635, 'source_name': 'stomach 20wk', 'full_rpkm': 1.0493, 'exp_rpkm': 1.05, 'var': 0.350091, 'project_desc': 'PRJNA270632', '_version_': 1785734396546908180}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 3635, "sample_id": "SAMN03267754", "full_rpkm": 0.498265, "exp_rpkm": 0.498, "exp_total": 12760, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 3635, "sample_id": "SAMN03267755", "full_rpkm": 0.369159, "exp_rpkm": 0.369, "exp_total": 14161, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 3635, "sample_id": "SAMN03267761", "full_rpkm": 0.466557, "exp_rpkm": 0.467, "exp_total": 16435, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 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"metadata_9606_SAMN03267777", "gene": 3635, "sample_id": "SAMN03267777", "full_rpkm": 0.0743625, "exp_rpkm": 0.0744, "exp_total": 4034, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 3635, "sample_id": "SAMN03267770", "full_rpkm": 0.545736, "exp_rpkm": 0.546, "exp_total": 17143, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 3635, "sample_id": "SAMN03267767", "full_rpkm": 0.449007, "exp_rpkm": 0.449, "exp_total": 12395, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", "gene": 3635, "sample_id": "SAMN03267778", "full_rpkm": 0.816881, "exp_rpkm": 0.817, "exp_total": 26960, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 3635, "sample_id": "SAMN03267776", "full_rpkm": 0.907078, "exp_rpkm": 0.907, "exp_total": 17918, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 3635, "sample_id": "SAMN03267780", "full_rpkm": 0.666088, "exp_rpkm": 0.666, "exp_total": 32584, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 3635, "sample_id": "SAMN03267768", "full_rpkm": 0.768562, "exp_rpkm": 0.769, "exp_total": 25764, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 3635, "sample_id": "SAMN03267773", "full_rpkm": 0.300058, "exp_rpkm": 0.3, "exp_total": 10422, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 3635, "sample_id": "SAMN03267779", "full_rpkm": 0.750984, "exp_rpkm": 0.751, "exp_total": 28668, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 3635, "sample_id": "SAMN03267774", "full_rpkm": 0.735681, "exp_rpkm": 0.736, "exp_total": 24145, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 3635, "sample_id": "SAMN03267771", "full_rpkm": 0.935003, "exp_rpkm": 0.935, "exp_total": 28718, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 3635, "sample_id": "SAMN03267765", "full_rpkm": 1.88604, "exp_rpkm": 1.89, "exp_total": 44733, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 3635, "sample_id": "SAMN03267781", "full_rpkm": 0.636744, "exp_rpkm": 0.637, "exp_total": 15343, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 3635, "sample_id": "SAMN03267783", "full_rpkm": 0.625115, "exp_rpkm": 0.625, "exp_total": 15849, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/22575191/" ref="ordinalpos=1&ncbi_uid=3635&link_uid=22575191">[Effect of SHIP mutation on invasion and migration of K562 leukemia cells].</a>
|
||
<span class="pubmed-auth-date"> Liu XJ, <em>et al</em>. Zhonghua Xue Ye Xue Za Zhi, 2012 Jan. PMID 22575191</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/32005521/" ref="ordinalpos=2&ncbi_uid=3635&link_uid=32005521">Characterization of the substrate specificity of the inositol 5-phosphatase SHIP1.</a>
|
||
<span class="pubmed-auth-date"> Nelson N, <em>et al</em>. Biochem Biophys Res Commun, 2020 Apr 2. PMID 32005521</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/9531585/" ref="ordinalpos=3&ncbi_uid=3635&link_uid=9531585">The SH2-containing inositol polyphosphate 5-phosphatase, ship, is expressed during hematopoiesis and spermatogenesis.</a>
|
||
<span class="pubmed-auth-date"> Liu Q, <em>et al</em>. Blood, 1998 Apr 15. PMID 9531585</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/31319229/" ref="ordinalpos=4&ncbi_uid=3635&link_uid=31319229">Targeted genetic analysis of cerebral blood flow imaging phenotypes implicates the INPP5D gene.</a>
|
||
<span class="pubmed-auth-date"> Yao X, <em>et al</em>. Neurobiol Aging, 2019 Sep. PMID 31319229, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC6732252/" ref="ordinalpos=0&ncbi_uid=3635&link_uid=PMC6732252">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30720128/" ref="ordinalpos=5&ncbi_uid=3635&link_uid=30720128">SHIP1 inhibits cell growth, migration, and invasion in non‑small cell lung cancer through the PI3K/AKT pathway.</a>
|
||
<span class="pubmed-auth-date"> Fu Q, <em>et al</em>. Oncol Rep, 2019 Apr. PMID 30720128</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=3635" title="See all 171 citations in Pubmed">See all (171) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/39176091" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=39176091">Potentially functional variants of INPP5D and EXOSC3 in immunity B cell-related genes are associated with non-small cell lung cancer survival.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: Potentially functional variants of INPP5D and EXOSC3 in immunity B cell-related genes are associated with non-small cell lung cancer survival.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38613944" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=38613944">SHIP inhibition mediates select TREM2-induced microglial functions.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: SHIP inhibition mediates select TREM2-induced microglial functions.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38309262" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=38309262">Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38016942" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=38016942">INPP5D regulates inflammasome activation in human microglia.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: INPP5D regulates inflammasome activation in human microglia.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37895194" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=37895194">INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer's Disease Pathophysiology.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: INPP5D/SHIP1: Expression, Regulation and Roles in Alzheimer's Disease Pathophysiology.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36981033" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=36981033">Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer's Disease Neuropathology and Genetics.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: Expression of INPP5D Isoforms in Human Brain: Impact of Alzheimer's Disease Neuropathology and Genetics.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37207939" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=37207939">Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36958526" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=36958526">Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37108169" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=37108169">Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36923408" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=3635&link_uid=36923408">CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: CircRNA_0075723 protects against pneumonia-induced sepsis through inhibiting macrophage pyroptosis by sponging miR-155-5p and regulating SHIP1 expression.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=3635&sym=INPP5D&name=inositol polyphosphate-5-phosphatase D&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=3635&symbol=INPP5D;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=3635" class="seeall-generif">See all GeneRIFs (79)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=INPP5D[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=3635">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/22412388">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/22412388">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23128233">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23128233">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21378990">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21378990">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24162737">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24162737">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24152035">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24152035">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=INPP5D[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=3635" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=3635[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=3635[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28876544">Envelope surface glycoprotein gp120</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 gp120 upregulates the expression of inositol polyphosphate-5-phosphatase, 145kDa (INPP5D) in human B cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 24162774" href="/pubmed/24162774">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-pathways">
|
||
<section class="rprt-section-header" id="pathways">
|
||
<h2 id="header-pathways">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<ul class="geneinfo-subsec infopathway">
|
||
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/3635#section=Pathways&embed=true&hide_all_headings=true&page_size=25" style="border: 0; width: 100%;"></iframe>
|
||
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
|
||
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/3635/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">G29434 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=10754%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=10754">UniSTS:10754</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-148855 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=176648%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=176648">UniSTS:176648</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">SHGC-148856 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=176649%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=176649">UniSTS:176649</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D11S2921 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=152074%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=152074">UniSTS:152074</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">SHGC-142327 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=171392%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=171392">UniSTS:171392</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">INPP5D_160 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=277386%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=277386">UniSTS:277386</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D2S1279 (e-PCR), detects polymorphism<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=149411%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=149411">UniSTS:149411</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">RH68049 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=63658%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=63658">UniSTS:63658</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">GDB:335751 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=156601%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=156601">UniSTS:156601</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-61987 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=39880%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=39880">UniSTS:39880</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH68337 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=6352%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=6352">UniSTS:6352</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">AFMa053wc5 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=35804%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=35804">UniSTS:35804</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH70363 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=47598%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=3635&link_uid=47598">UniSTS:47598</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/3635/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
<div class="infosec info-comment" id="info-comment">
|
||
<h3 id="CloneNames">
|
||
<a class="jig-ncbitoggler-open">Clone Names</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>MGC104855, MGC142140, MGC142142 </li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0017124">enables SH3 domain binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0052659">enables inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004445">enables inositol-polyphosphate 5-phosphatase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/10764818" target="_blank" title="PubMed ID 10764818" ref="ordinalpos=1&ncbi_uid=3635&link_uid=10764818">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016314">enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0034485">enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-5-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004439">enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-7-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/9148918,9485206,10382761,15090612,16339535,19843936,20933011,21712384,24642916,25416956,26221972,26755705,32296183" target="_blank" title="PubMed ID 9148918,9485206,10382761,15090612,16339535,19843936,20933011,21712384,24642916,25416956,26221972,26755705,32296183" ref="ordinalpos=1&ncbi_uid=3635&link_uid=9148918,9485206,10382761,15090612,16339535,19843936,20933011,21712384,24642916,25416956,26221972,26755705,32296183">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0050852">involved_in T cell receptor signaling pathway</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-1-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006915">involved_in apoptotic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008340">involved_in determination of adult lifespan</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-3-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016064">involved_in immunoglobulin mediated immune response</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035556">involved_in intracellular signal transduction</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0030889">involved_in negative regulation of B cell proliferation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045779">involved_in negative regulation of bone resorption</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-7-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0032715">involved_in negative regulation of interleukin-6 production</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-8-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045656">involved_in negative regulation of monocyte differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-9-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045953">involved_in negative regulation of natural killer cell mediated cytotoxicity</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-10-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/23154388" target="_blank" title="PubMed ID 23154388" ref="ordinalpos=1&ncbi_uid=3635&link_uid=23154388">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045659">involved_in negative regulation of neutrophil differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-11-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045671">involved_in negative regulation of osteoclast differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-12-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0009968">involved_in negative regulation of signal transduction</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-13-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006796">involved_in phosphate-containing compound metabolic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-14-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8769125" target="_blank" title="PubMed ID 8769125" ref="ordinalpos=1&ncbi_uid=3635&link_uid=8769125">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006661">involved_in phosphatidylinositol biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-15-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0046856">involved_in phosphatidylinositol dephosphorylation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-16-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045579">involved_in positive regulation of B cell differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-17-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0043065">involved_in positive regulation of apoptotic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-18-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-18-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045648">involved_in positive regulation of erythrocyte differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-19-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-19-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0050776">involved_in regulation of immune response</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-20-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-20-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0007165">involved_in signal transduction</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-21-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-21-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8769125" target="_blank" title="PubMed ID 8769125" ref="ordinalpos=1&ncbi_uid=3635&link_uid=8769125">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">is_active_in cytoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/10822173" target="_blank" title="PubMed ID 10822173" ref="ordinalpos=1&ncbi_uid=3635&link_uid=10822173">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005856">located_in cytoskeleton</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">is_active_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-5-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045121">located_in membrane raft</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-7-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>SH2 domain-containing inositol 5'-phosphatase 1</dd>
|
||
<dd>inositol polyphosphate-5-phosphatase, 145kD</dd>
|
||
<dd>inositol polyphosphate-5-phosphatase, 145kDa</dd>
|
||
<dd>phosphatidylinositol 4,5-bisphosphate 5-phosphatase</dd>
|
||
<dd>signaling inositol polyphosphate 5 phosphatase SIP-145</dd>
|
||
<dd>signaling inositol polyphosphate phosphatase SHIP II</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001017915.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_005532.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047300175.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047300176.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054187655.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054187656.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054197847.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054197848.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.36">3.1.3.36</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.56">3.1.3.56</a></li>
|
||
</ul>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.1.3.86">3.1.3.86</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=3635&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p34546208">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_033988.1 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5376..152937</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_033988.1?from=5376&to=152937&report=genbank" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NG_033988.1?from=5376&to=152937&report=genbank">GenBank</a>, <a href="/nuccore/NG_033988.1?from=5376&to=152937&report=fasta" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NG_033988.1?from=5376&to=152937&report=fasta">FASTA</a>, <a href="/nuccore/NG_033988.1?from=1&to=175070&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NG_033988.1?from=1&to=175070&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p109641008">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001017915.3">NM_001017915.3</a> → <a href="/protein/NP_001017915.1">NP_001017915.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform a</p>
|
||
<p>
|
||
<a href="/ipg/NP_001017915.1/" ref="ncbi_uid=3635">See identical proteins and their annotated locations for NP_001017915.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AW503130, BC099920, U53470">AW503130, BC099920, U53470</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS74672.1">CCDS74672.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/O00145" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">O00145</a>, <a href="https://www.uniprot.org/uniprot/Q13544" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q13544</a>, <a href="https://www.uniprot.org/uniprot/Q13545" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q13545</a>, <a href="https://www.uniprot.org/uniprot/Q6P5A4" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q6P5A4</a>, <a href="https://www.uniprot.org/uniprot/Q92656" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q92656</a>, <a href="https://www.uniprot.org/uniprot/Q92835" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q92835</a>, <a href="https://www.uniprot.org/uniprot/Q9UE80" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q9UE80</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000405338.2" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">ENSP00000405338.2</a>, <a href="http://www.ensembl.org/id/ENST00000445964.6" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">ENST00000445964.6</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001017915.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=197334">cd09100</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">404</span> → <span class="cddto">710</span></dt>
|
||
<dd class="clearfix"> INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=198206">cd10343</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">102</span></dt>
|
||
<dd class="clearfix"> SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=223039">PHA03307</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">899</span> → <span class="cddto">1127</span></dt>
|
||
<dd class="clearfix"> PHA03307; transcriptional regulator ICP4; Provisional</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_005541.5">NM_005541.5</a> → <a href="/protein/NP_005532.2">NP_005532.2</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b</p>
|
||
<p>
|
||
<a href="/ipg/NP_005532.2/" ref="ncbi_uid=3635">See identical proteins and their annotated locations for NP_005532.2</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is 1 aa shorter than isoform a.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AW503130, BC099920, X98429">AW503130, BC099920, X98429</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS77543.1">CCDS77543.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q92835" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">Q92835</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000352575.7" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">ENSP00000352575.7</a>, <a href="http://www.ensembl.org/id/ENST00000359570.9" ref="itool=Gene_FullReport&PrId=5380&uid=3635&nlmid=&db=gene">ENST00000359570.9</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_005532.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=197334">cd09100</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">403</span> → <span class="cddto">709</span></dt>
|
||
<dd class="clearfix"> INPP5c_SHIP1-INPP5D; Catalytic inositol polyphosphate 5-phosphatase (INPP5c) domain of SH2 domain containing inositol polyphosphate 5-phosphatase-1 and related proteins</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=198206">cd10343</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">102</span></dt>
|
||
<dd class="clearfix"> SH2_SHIP; Src homology 2 (SH2) domain found in SH2-containing inositol-5'-phosphatase (SHIP) and SLAM-associated protein (SAP)</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p16875392">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p16875392">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000002.12 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>233060342..233207903</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000002.12?from=233060342&to=233207903&report=genbank" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12?from=233060342&to=233207903&report=genbank">GenBank</a>, <a href="/nuccore/NC_000002.12?from=233060342&to=233207903&report=fasta" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12?from=233060342&to=233207903&report=fasta">FASTA</a>, <a href="/nuccore/NC_000002.12?from=233038207&to=233230036&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_000002.12?from=233038207&to=233230036&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p3849072">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047444219.1">XM_047444219.1</a> → <a href="/protein/XP_047300175.1">XP_047300175.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047444220.1">XM_047444220.1</a> → <a href="/protein/XP_047300176.1">XP_047300176.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p105682288">Reference GRCh38.p14 PATCHES</h3>
|
||
<h4 id="genomic-p105682288">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NW_011332690.1 Reference GRCh38.p14 PATCHES</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5680..153241</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NW_011332690.1?from=5680&to=153241&report=genbank" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NW_011332690.1?from=5680&to=153241&report=genbank">GenBank</a>, <a href="/nuccore/NW_011332690.1?from=5680&to=153241&report=fasta" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NW_011332690.1?from=5680&to=153241&report=fasta">FASTA</a>, <a href="/nuccore/NW_011332690.1?from=1&to=175374&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NW_011332690.1?from=1&to=175374&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p82821888">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054331680.1">XM_054331680.1</a> → <a href="/protein/XP_054187655.1">XP_054187655.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054331681.1">XM_054331681.1</a> → <a href="/protein/XP_054187656.1">XP_054187656.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p61677776">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p61677776">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060926.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>233547692..233695995</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060926.1?from=233547692&to=233695995&report=genbank" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_060926.1?from=233547692&to=233695995&report=genbank">GenBank</a>, <a href="/nuccore/NC_060926.1?from=233547692&to=233695995&report=fasta" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_060926.1?from=233547692&to=233695995&report=fasta">FASTA</a>, <a href="/nuccore/NC_060926.1?from=233525446&to=233718239&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=3635&link_uid=NC_060926.1?from=233525446&to=233718239&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p57057600">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054341872.1">XM_054341872.1</a> → <a href="/protein/XP_054197847.1">XP_054197847.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054341873.1">XM_054341873.1</a> → <a href="/protein/XP_054197848.1">XP_054197848.1</a> phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X2</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/3635/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">Q92835.2</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/158564077" ref="ordinalpos=1&ncbi_uid=3635&link_uid=158564077">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/Q92835">UniProtKB/Swiss-Prot:Q92835</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/INPP5D?lang=en&region=US" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>Inpp5d products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000168918" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>INPP5D gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/3635/" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (20 hits/490 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>INPP5D</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/Q92835" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1455" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8191">
|
||
<span>INPP5D gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D3635%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=83441" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000168918" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN67596/" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN67597/" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Gene Wiki</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://en.wikipedia.org/wiki/INPP5D" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=6933">
|
||
<span>The Gene Wiki</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=INPP5D" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for INPP5D</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ship/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SHIP Proteins</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ship/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SHIP Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ship/elisa-kits?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=elisakits" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SHIP ELISA Kits</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/SHIP-antibody.html" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/SHIP-antibody.html" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&field=5&key=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order TALEN/CRISPR clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=3635&type=01&page=1" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=INPP5D" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order INPP5D cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=3635" ref="itool=Gene_FullReport&uid=3635&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#pathways">Pathways from PubChem</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/3635" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&from_uid=3635" ref="log$=recordlinks">3D structures</a>
|
||
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=3635" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=3635" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=3635" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=3635" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=3635" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=3635" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=3635" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=3635" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=3635" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=3635" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=3635" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=3635" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=3635" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&from_uid=3635" ref="log$=recordlinks">GAP</a>
|
||
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=3635" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=3635" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=3635" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=3635" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=3635[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=3635" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=3635" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=3635" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=3635" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=3635" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=3635" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=3635" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=3635" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=3635" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=3635" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=3635" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=3635" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=3635" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/589269252?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=3635" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=3635" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=3635[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6079">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000168918">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:6079">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=3635">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.pharmgkb.org/gene/PA29887">PharmGKB</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_001017915">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC099920">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=INPP5D&geneID=3635&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:3635">KEGG</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=3635&symbol=INPP5D">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=3635&sym=INPP5D&name=inositol polyphosphate-5-phosphatase D&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9e000a68b6b5afc6fd6e9">INPP5D inositol polyphosphate-5-phosphatase D [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">INPP5D inositol polyphosphate-5-phosphatase D [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:3635</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9dfff84f3725e5937ead1">phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b [Homo sapiens...</a>
|
||
<div class="ralinkpop offscreen_noflow">phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform b [Homo sapiens]<div class="brieflinkpopdesc">gi|40254823|ref|NP_005532.2|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9dffda68b6b5afc6fc667">INHBA inhibin subunit beta A [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">INHBA inhibin subunit beta A [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:3624</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9dffca68b6b5afc6fb9a5">inhibin beta A chain preproprotein [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">inhibin beta A chain preproprotein [Homo sapiens]<div class="brieflinkpopdesc">gi|4504699|ref|NP_002183.1|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9dffa84f3725e5937cf92">INA internexin neuronal intermediate filament protein alpha [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">INA internexin neuronal intermediate filament protein alpha [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:9118</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
</ul>
|
||
<p class="HTOn">Your browsing activity is empty.</p>
|
||
<p class="HTOff">Activity recording is turned off.</p>
|
||
<p id="turnOn" class="HTOff">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
|
||
</p>
|
||
<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="NCBIFooter_dynamic">
|
||
<!--<component id="NCBIBreadcrumbs"/>
|
||
<component id="NCBIHelpDesk"/>-->
|
||
<noscript><img alt="" src="/stat?jsdisabled=true&ncbi_app=entrez&ncbi_db=gene&ncbi_pdid=full_report&ncbi_phid=CE8A36CC7C9DBCE100000000001A0019" /></noscript>
|
||
</div>
|
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||
<div xmlns="http://www.w3.org/1999/xhtml" class="footer" id="footer" xml:base="http://127.0.0.1/sites/static/header_footer/">
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||
<section class="icon-section">
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<div id="icon-section-header" class="icon-section_header">Follow NCBI</div>
|
||
<div class="grid-container container">
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||
<div class="icon-section_container">
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||
<a class="footer-icon" id="footer_twitter" href="https://twitter.com/ncbi" aria-label="Twitter">
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<svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40" fill="none">
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<title>Twitter</title>
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<g id="twitterx1008">
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<path id="path1008" d="M6.06736 7L16.8778 20.8991L6.00001 32.2H10.2L18.6 23.1L25.668 32.2H34L22.8 17.5L31.9 7H28.4L20.7 15.4L14.401 7H6.06898H6.06736ZM9.66753 8.73423H12.9327L29.7327 30.4658H26.5697L9.66753 8.73423Z" fill="#5B616B"></path>
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<a class="footer-icon" id="footer_facebook" href="https://www.facebook.com/ncbi.nlm" aria-label="Facebook"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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<title>Facebook</title>
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<path class="cls-11" d="M210.5,115.12H171.74V97.82c0-8.14,5.39-10,9.19-10h27.14V52l-39.32-.12c-35.66,0-42.42,26.68-42.42,43.77v19.48H99.09v36.32h27.24v109h45.41v-109h35Z">
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<a class="footer-icon" id="footer_linkedin" href="https://www.linkedin.com/company/ncbinlm" aria-label="LinkedIn"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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<title>LinkedIn</title>
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