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170 lines
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<title>9FZZ: Structure of carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) in complex with corrinoid iron-sulfur protein (CoFeSP) from Clostridium autoethanogenum (composite structure, class 3B)</title>
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<meta name="description" content="Acetyl-CoA decarbonylase/synthase complex subunit deltaCO-methylating acetyl-CoA synthaseCarbon monoxide dehydrogenase/acetyl-CoA synthase beta subunitCorrinoid iron-sulfur protein large subunit">
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<meta name="keywords" content="Acetyl-CoA decarbonylase/synthase complex subunit delta, CO-methylating acetyl-CoA synthase, Carbon monoxide dehydrogenase/acetyl-CoA synthase beta subunit, Corrinoid iron-sulfur protein large subunit, COBALAMIN, Fe(3)-Ni(1)-S(4) cluster, IRON/SULFUR CLUSTER, NICKEL (II) ION, MMDB, Protein structure, protein interaction">
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<section data-section="infor" id="structure-infor-section"><h1 class="structure-title" data-mmdbid="259012" data-pdbid="9FZZ" id="structure-title"><a class="link title-pdbid" href="http://www.rcsb.org/pdb/explore/explore.do?structureId=9FZZ" style="font-weight:600;margin:0;">9FZZ: </a><span>Structure of carbon monoxide dehydrogenase/acetyl-CoA synthase (CODH/ACS) in complex with corrinoid iron-sulfur protein (CoFeSP) from Clostridium autoethanogenum (composite structure, class 3B)</span></h1>
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<div class="floatClear" id="infor-detail"><div class="reference_section" data-pmids="39883773" id="reference-section"></div>
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<div class="property_section"><form action="/Structure/mmdb/mmdbsrv.cgi" method="post" id="reloadform" name="reloadform" style="margin:0;padding:0"><input type="hidden" name="uid" value="259012"/></form><table border="0" cellpadding="4" cellspacing="4"><tr><td class="H4 pdbid-download">PDB ID: </td>
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<td><a id="pdb_id_link" class="link" href="http://www.rcsb.org/pdb/explore/explore.do?structureId=9FZZ" title="PDB ID">9FZZ</a><a id="download-pdb-file" class="__button" tabindex="-1" href="https://files.rcsb.org/download/9FZZ.pdb" title="Download PDB file" download="9FZZ.pdb">Download</a><a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvStructureViewDataSetPDBdataset" title="-click to see help"></a></td>
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<tr><td class="H4 property-name">MMDB ID: </td>
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<td style="font-weight:bold"><span class="info-item">259012</span> <a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvRecordIdentifiers" title="-click to see help"></a></td>
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<tr><td class="H4 property-name">PDB Deposition Date: </td>
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<td><span id="depositionterm" style="padding-left: 0.2em;">2024/7/6<a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvDeposited" title="-click to see help"></a></span></td>
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<tr><td class="H4 property-name">Updated in MMDB: </td>
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<td class="text" nowrap><span id="mmdb_updated" style="padding-left:0.2em">2025/02</span><a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvUpdatedInMMDB" title="-click to see help"></a></td>
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<tr><td class="H4 property-name">Experimental Method: </td>
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<td class="TEXT" nowrap><div id="expmethod"><span title="electron microscopy" class="info-item">electron microscopy</span> <a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvExperimentalMethod" title="-click to see help"></a></div></td>
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<tr><td class="H4 property-name">Resolution: </td>
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<td class="TEXT" id="resolution" nowrap>2.65 Å<a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#SearchFieldResolution" title="-click to see help"></a></td>
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<tr><td class="H4 property-name">Source Organism: </td>
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<td class="text"><div id="taxonomy"><a id="taxword" class="link" href="//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?lvl=0&id=1341692" title="Clostridium autoethanogenum DSM 10061">Clostridium autoethanogenum DSM 10061</a><a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvTaxonomy" title="-click to see help"></a></div></td>
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<tr><td class="H4 property-name">Similar Structures: </td>
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<td><div id="vast-button-holder" style="width:100%;overflow:hidden;"><button class="__button" id="vast_button" type="submit">VAST+</button>
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<a class="help-img" href="/Structure/vastplus/docs/vastplus_help.html" title="-click to see help"></a></div></td>
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<a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvDownaloadSequenceMMDB" title="-click to see help"></a></td></tr>
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<div align="center" id="annotblock" style="margin-top:0.8em;"><div class="formbox" id="authormethod"><div id="bublock0"><div class="biotext" id="bublock0_unit_name">Biological Unit for 9FZZ: hexameric; determined by author and by software <a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvBiologicalUnit" title="-click to see help"></a></div>
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<style>.unitschema-1{
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background-image:url("/Structure/mmdb/mmdbimage.fcgi?uid=259012&type=2&unm=1");
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}</style><section class="graph-section" data-section="graph" id="biounit-section-1"></section>
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<section class="content_block" data-section="table"><table border="1" class="bucontent"><caption class="butbl_caption">Molecular Components in 9FZZ<a class="help-img" href="/Structure/MMDB/docs/mmdb_help.html#MmdbsrvMolecularComponents" title="-click to see help"></a></caption>
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<thead><tr><th>Label</th>
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<th>Count</th>
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<th>Molecule</th>
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</tr></thead>
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<tbody data-bun="1" data-type="protein" id="unit1_protein_annotation"><tr><td class="butbl_inner_tbl_tit" colspan="3"><div style="float:left">Proteins (6 molecules)</div></td></tr>
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<tr data-row="0"><td class="molecule-label-cell"><div class="identical-molecules floatClear" id="chain-list-1-1" style="text-align: center;"><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_D" id="mol-legend-1-1" class="protein-molecule-label-1" data-gi="2901697456" data-molid="1" style="color:#FFFFFF;background-color:#FF00FF" title="-Select icon for molecule information"><div class="protein-table-chain-label">D</div></a><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_A" id="mol-legend-1-3" class="protein-molecule-label-1" data-gi="2901697458" data-molid="3" style="color:#FFFFFF;background-color:#996633" title="-Select icon for molecule information"><div class="protein-table-chain-label">A</div></a></div></td>
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<td>2</td>
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<td class="annotation-cell"><div class="graph-annot"><div class="molecule-name" title="Co-methylating Acetyl-coa Synthase">Co-methylating Acetyl-coa Synthase</div>
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<div class="annot-img-block" data-bun="1" data-gmolid="1" data-molids="1,3" id="molgraph-p-1-1"><img alt="Molecule annotation" src="/Structure/mmdb/images/bigLoader.gif"></div>
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</div></td>
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</tr>
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<tr data-row="1"><td class="molecule-label-cell"><div class="identical-molecules floatClear" id="chain-list-1-2" style="text-align: center;"><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_E" id="mol-legend-1-2" class="protein-molecule-label-1" data-gi="2901697457" data-molid="2" style="color:#FFFFFF;background-color:#0000FF" title="-Select icon for molecule information"><div class="protein-table-chain-label">E</div></a></div></td>
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<td>1</td>
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<td class="annotation-cell"><div class="graph-annot"><div class="molecule-name" title="Acetyl-coa Decarbonylase/synthase Complex Subunit Delta">Acetyl-coa Decarbonylase/synthase Complex Subunit Delta</div>
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<div class="annot-img-block" data-bun="1" data-gmolid="2" data-molids="2" id="molgraph-p-1-2"><img alt="Molecule annotation" src="/Structure/mmdb/images/bigLoader.gif"></div>
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</div></td>
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</tr>
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<tr data-row="2"><td class="molecule-label-cell"><div class="identical-molecules floatClear" id="chain-list-1-3" style="text-align: center;"><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_B" id="mol-legend-1-4" class="protein-molecule-label-1" data-gi="2901697459" data-molid="4" style="color:#000000;background-color:#00FF99" title="-Select icon for molecule information"><div class="protein-table-chain-label">B</div></a><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_C" id="mol-legend-1-5" class="protein-molecule-label-1" data-gi="2901697460" data-molid="5" style="color:#000000;background-color:#CCCCCC" title="-Select icon for molecule information"><div class="protein-table-chain-label">C</div></a></div></td>
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<td>2</td>
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<td class="annotation-cell"><div class="graph-annot"><div class="molecule-name" title="Carbon Monoxide Dehydrogenase/acetyl-coa Synthase Beta Subunit">Carbon Monoxide Dehydrogenase/acetyl-coa Synthase Beta Subunit</div>
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<div class="annot-img-block" data-bun="1" data-gmolid="4" data-molids="4,5" id="molgraph-p-1-4"><img alt="Molecule annotation" src="/Structure/mmdb/images/bigLoader.gif"></div>
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</div></td>
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</tr>
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<tr data-row="3"><td class="molecule-label-cell"><div class="identical-molecules floatClear" id="chain-list-1-4" style="text-align: center;"><a href="//www.ncbi.nlm.nih.gov/protein/9FZZ_F" id="mol-legend-1-6" class="protein-molecule-label-1" data-gi="2901697461" data-molid="6" style="color:#000000;background-color:#FF9900" title="-Select icon for molecule information"><div class="protein-table-chain-label">F</div></a></div></td>
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<td>1</td>
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<td class="annotation-cell"><div class="graph-annot"><div class="molecule-name" title="Corrinoid Iron-sulfur Protein Large Subunit">Corrinoid Iron-sulfur Protein Large Subunit</div>
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<div class="annot-img-block" data-bun="1" data-gmolid="6" data-molids="6" id="molgraph-p-1-6"><img alt="Molecule annotation" src="/Structure/mmdb/images/bigLoader.gif"></div>
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</div></td>
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</tr>
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</tbody>
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<tbody data-bun="1" data-type="chemical" id="unit1_chemical_annotation"><tr><td class="butbl_inner_tbl_tit" colspan="3"><div style="float:left">Chemicals and Non-standard biopolymers (10 molecules)</div></td></tr>
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<tr><td data-row="0"><div class="chem-label-box"><span class="chemical-molecule-label" id="mol-chem-legend-1-1" title="-Select icon for PubChem compound information"><a class="link chem_label" data-molids="7,10,11,13,15" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384933">1</a></span></div></td>
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<td><div class="chem-label">5</div></td>
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<td><div class="chem-name-thumb floatClear"><span class="chem-name" data-sid="505384933"><a class="link mmdb-chem-name" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384933" title="IRON/SULFUR CLUSTER">IRON/SULFUR CLUSTER</a></span><span class="chem-image-holder" title="IRON/SULFUR CLUSTER"><a href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384933"><img type="thumb" class="chemthumb" align="absmiddle" src="//pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?sid=505384933" alt="IRON/SULFUR CLUSTER"></a></span></div></td>
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</tr>
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<tr><td data-row="1"><div class="chem-label-box"><span class="chemical-molecule-label" id="mol-chem-legend-1-2" title="-Select icon for PubChem compound information"><a class="link chem_label" data-molids="8,9" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384934">2</a></span></div></td>
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<td><div class="chem-label">2</div></td>
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<td><div class="chem-name-thumb floatClear"><span class="chem-name" data-sid="505384934"><a class="link mmdb-chem-name" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384934" title="NICKEL (II) ION">NICKEL (II) ION</a></span><span class="chem-image-holder" title="NICKEL (II) ION"><a href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384934"><img type="thumb" class="chemthumb" align="absmiddle" src="//pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?sid=505384934" alt="NICKEL (II) ION"></a></span></div></td>
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</tr>
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<tr><td data-row="2"><div class="chem-label-box"><span class="chemical-molecule-label" id="mol-chem-legend-1-3" title="-Select icon for PubChem compound information"><a class="link chem_label" data-molids="12,14" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384936">3</a></span></div></td>
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<td><div class="chem-label">2</div></td>
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<td><div class="chem-name-thumb floatClear"><span class="chem-name" data-sid="505384936"><a class="link mmdb-chem-name" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384936" title="Fe(3)-Ni(1)-S(4) cluster">Fe(3)-Ni(1)-S(4) cluster</a></span><span class="chem-image-holder" title="Fe(3)-Ni(1)-S(4) cluster"><a href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384936"><img type="thumb" class="chemthumb" align="absmiddle" src="//pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?sid=505384936" alt="Fe(3)-Ni(1)-S(4) cluster"></a></span></div></td>
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</tr>
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<tr><td data-row="3"><div class="chem-label-box"><span class="chemical-molecule-label" id="mol-chem-legend-1-4" title="-Select icon for PubChem compound information"><a class="link chem_label" data-molids="16" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384937">4</a></span></div></td>
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<td><div class="chem-label">1</div></td>
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<td><div class="chem-name-thumb floatClear"><span class="chem-name" data-sid="505384937"><a class="link mmdb-chem-name" href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384937" title="COBALAMIN">COBALAMIN</a></span><span class="chem-image-holder" title="COBALAMIN"><a href="//pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=505384937"><img type="thumb" class="chemthumb" align="absmiddle" src="//pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?sid=505384937" alt="COBALAMIN"></a></span></div></td>
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</tr>
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</tbody>
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</table>
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<div style="margin:0.5em 1em;text-align:left; font-size:85%;">* Click molecule labels to explore molecular sequence information.<br/></div>
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</section>
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</div></div></div>
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<!-- end annotations -->
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</td></tr>
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</table>
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<div align="left" class="citing"><hr width="85%"/><div style="font-weight:bold">Citing MMDB</div><div class="citref" style="padding:0.2em;"><img style="border:0;text-align:left;height:15px;width:15px;margin-right:0.2em" src="//pubchem.ncbi.nlm.nih.gov/images/PubMed.gif"> <span style="color:#444"> Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. </span> <cite><a class="link" href="//www.ncbi.nlm.nih.gov/pubmed/24319143">"<span style="font-style:italic;"> MMDB and VAST+: tracking structural similarities between macromolecular complexes. <b style="font-size:90%">Nucleic Acids Res. 2014 Jan; 42(Database issue)</b>:D297-303</span></a></cite></div></div>
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