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<title>TREM2 variants in Alzheimer's disease - PubMed</title>
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<meta name="description" content="Heterozygous rare variants in TREM2 are associated with a significant increase in the risk of Alzheimer's disease. 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Author(firstnames='Dominique', lastname='Campion', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Annick', lastname='Alpérovitch', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marc', lastname='Lathrop', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Colin', lastname='Smith', initials='C', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Daniah', lastname='Trabzuni', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Robert', lastname='Walker', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Mike', lastname='Weale', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False)], affs=[]), Aged, Alzheimer Disease / genetics*, Alzheimer Disease / pathology, Animals, Brain / pathology, Exome / genetics, Genetic Variation, Genome-Wide Association Study, Genotype, Genotyping Techniques, Heterozygote, Humans, Membrane Glycoproteins / genetics*, Membrane Glycoproteins / metabolism, Mice, Mice, Inbred A, Mutation*, RNA, Messenger / metabolism, Receptors, Immunologic / genetics*, Receptors, Immunologic / metabolism, Risk Factors, Sequence Analysis, DNA / methods, PubMed Abstract, NIH, NLM, NCBI, National Institutes of Health, National Center for Biotechnology Information, National Library of Medicine, MEDLINE"><meta name="robots" content="index,nofollow,noarchive"><meta property="og:title" content="TREM2 variants in Alzheimer's disease - PubMed"><meta property="og:url" content="https://pubmed.ncbi.nlm.nih.gov/23150934/"><meta property="og:description" content="Heterozygous rare variants in TREM2 are associated with a significant increase in the risk of Alzheimer's disease. 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|
||
<select name="format" data-initial-value="abstract" aria-label="Display format" id="article-display-format">
|
||
<option value="abstract">Abstract</option>
|
||
|
||
<option value="pubmed">PubMed</option>
|
||
|
||
<option value="pmid">PMID</option>
|
||
|
||
</select>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="article-panels-container" class="article-panels-container">
|
||
<div id="save-action-panel" class="save-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Save citation to file
|
||
</h2>
|
||
<form id="save-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="save-action-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="save-action-format" name="results-format" class="action-panel-selector">
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="pubmed-text">PubMed</option>
|
||
<option value="pmid">PMID</option>
|
||
<option value="abstract">Abstract (text)</option>
|
||
<option value="csv">CSV</option>
|
||
</select>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Save citations to file' panel"
|
||
ref="linksrc=close_save_panel"
|
||
aria-controls="save-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="email-action-panel"
|
||
class="email-action-panel action-panel"
|
||
aria-hidden="true"
|
||
data-recaptcha-script-url="https://www.recaptcha.net/recaptcha/enterprise.js?render=explicit&onload=onloadCaptchaCallback"
|
||
data-recaptcha-enabled="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Email citation
|
||
</h2>
|
||
<form id="email-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/send-email/"
|
||
data-by-search-action="/results-export-email-by-search-data/"
|
||
data-by-ids-action="/send-email/"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post"
|
||
method="post"
|
||
>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<span class="action-panel-label">
|
||
Subject:
|
||
</span>
|
||
<span class="email-subject" id="email-subject" aria-label="Email subject">1 selected item: 23150934 - PubMed</span>
|
||
<input type="hidden" name="email-subject" value="1 selected item: 23150934"/>
|
||
<input type="hidden" name="email-subject-hash" value="8285e16d6b60b1285832528f57d61e36a1ed33a29c85c0c5438bd2a2852495da"/>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-to" class="action-panel-label required-field-asterisk">
|
||
To:
|
||
</label>
|
||
<input type="email" aria-label="Recipient Email Address" placeholder="email@example.com" id="email-to" class="email-to" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="100" required>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-from" class="action-panel-label">
|
||
From:
|
||
</label>
|
||
<input type="email" aria-label="Sender Email Address" placeholder="email@example.com" id="email-from" class="email-from" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="256">
|
||
</div>
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-citation-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="email-citation-format" name="citation-format" class="action-panel-selector email-citation-format">
|
||
<option selected="selected" value="summary">Summary</option>
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="abstract">Abstract</option>
|
||
<option value="abstract-text">Abstract (text)</option>
|
||
|
||
</select>
|
||
</div>
|
||
<div class="include-supplemental-container">
|
||
<input type="checkbox" aria-label="Include MeSH and other data" name="include-supplemental" id="email-include-supplemental" class="email-include-supplemental">
|
||
<label for="email-include-supplemental" class="email-include-supplemental-label">MeSH and other data</label>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="form-field recaptcha ">
|
||
|
||
|
||
|
||
<div class="g-recaptcha" id="id-recaptcha" data-sitekey="6LfsWHMdAAAAAClKbtOpjQ2pMjgsGxvv7NdZW9uI"></div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div id="captcha-error-message" class="usa-input-error-message captcha-validation-message" role="alert"></div>
|
||
|
||
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="send">
|
||
Send email
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Email citations' panel"
|
||
ref="linksrc=close_email_panel"
|
||
aria-controls="email-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
<input type="hidden" name="email-search-details" value="" />
|
||
<input type="hidden" name="email-search-details-hash" value="0e42663a6c3bd85498fcb88798998fed7bfdc45d457db35281e41afe13cc0524" />
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="collections-action-panel"
|
||
class="collections-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-collections-open-panel-enabled="false"
|
||
data-collections-open-panel-url-hash="#open-collections-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to Collections
|
||
</h3>
|
||
|
||
|
||
<form id="collections-action-panel-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-add-to-collection-max-amount="1000"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
|
||
|
||
<div class="choice-group" role="radiogroup">
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_new">
|
||
<label for="collections-action-panel-new">Create a new collection</label>
|
||
</li>
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_existing">
|
||
<label for="collections-action-panel-existing">Add to an existing collection</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="controls-wrapper">
|
||
<div class="action-panel-control-wrap new-collections-controls">
|
||
<label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label>
|
||
<input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-panel-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="save_share"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection">
|
||
<div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div>
|
||
</div>
|
||
<div class="action-panel-control-wrap existing-collections-controls">
|
||
<label for="collections-action-panel-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label>
|
||
<select id="collections-action-panel-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="save_share"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'">
|
||
</select>
|
||
<div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="add">
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="bibliography-action-panel"
|
||
class="bibliography-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-bibliography-open-panel-enabled="false"
|
||
data-bibliography-open-panel-url-hash="#open-bibliography-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to My Bibliography
|
||
</h3>
|
||
<form id="bibliography-action-panel-form"
|
||
class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-add-to-bibliography-max-amount="100"
|
||
data-add-to-bibliography-batch-size="10"
|
||
data-bibliography-delegates-url="/list-bibliography-delegates/"
|
||
data-add-to-bibliography-url="/add-to-bibliography/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap bibliographies-controls">
|
||
<div class="choice-group">
|
||
<ul class="bibliographies-action-add radio-group-items">
|
||
<li>
|
||
<input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/>
|
||
<label for="my-bibliography">My Bibliography</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your delegates due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore>
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to bibliography' panel"
|
||
ref="linksrc=close_bibliography_panel"
|
||
aria-controls="bibliography-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="mybib"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true"
|
||
data-saved-search-open-panel-enabled="false"
|
||
data-saved-search-open-panel-url-hash="#open-saved-search-panel">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your saved search
|
||
</h2>
|
||
|
||
<form id="saved-search-action-panel-form"
|
||
class="saved-search-action-panel-form action-panel-content action-form"
|
||
data-create-saved-search-url="/create-saved-search/"
|
||
data-try-search-terms-url="/try-search-term/"
|
||
data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk">
|
||
Name of saved search:
|
||
</label>
|
||
<input maxlength="200"
|
||
type="text"
|
||
name="saved-search-name"
|
||
id="saved-search-name"
|
||
class="saved-search-name"
|
||
value=""
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-term" class="action-panel-label required-field-asterisk">
|
||
Search terms:
|
||
</label>
|
||
<textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea>
|
||
</div>
|
||
<div class="test-search-term-wrap">
|
||
<a href="#" class="try-search-term">Test search terms</a>
|
||
</div>
|
||
<div class="choice-group action-panel-extra-margin-top">
|
||
<span class="action-panel-label" id="fieldset-label">
|
||
Would you like email updates of new search results?
|
||
</span>
|
||
<fieldset id="saved-search-alert" aria-describedby="fieldset-label">
|
||
<legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend>
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked>
|
||
<label for="saved-search-alert-yes" class="action-panel-label">Yes</label>
|
||
</li>
|
||
<li>
|
||
<input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no">
|
||
<label for="saved-search-alert-no" class="action-panel-label">No</label>
|
||
</li>
|
||
</ul>
|
||
</fieldset>
|
||
</div>
|
||
|
||
<div class="alert-schedule-wrap">
|
||
<div class="action-panel-control-wrap">
|
||
<label class="action-panel-label">
|
||
Email:
|
||
</label>
|
||
<span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
|
||
</div>
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="saved-search-frequency" class="action-panel-label">
|
||
Frequency:
|
||
</label>
|
||
<select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency">
|
||
<option value="monthly">Monthly</option>
|
||
<option value="weekly">Weekly</option>
|
||
<option value="daily">Daily</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-monthly-additional">
|
||
<label for="saved-search-monthly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-monthly-on-day" class="no-border-panel-selector">
|
||
<option value="Sunday">The first Sunday</option>
|
||
<option value="Monday">The first Monday</option>
|
||
<option value="Tuesday">The first Tuesday</option>
|
||
<option value="Wednesday">The first Wednesday</option>
|
||
<option value="Thursday">The first Thursday</option>
|
||
<option value="Friday">The first Friday</option>
|
||
<option value="Saturday">The first Saturday</option>
|
||
<option value="day">The first day</option>
|
||
<option value="weekday">The first weekday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-weekly-additional">
|
||
<label for="saved-search-weekly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day">
|
||
<option value="Sunday">Sunday</option>
|
||
<option value="Monday">Monday</option>
|
||
<option value="Tuesday">Tuesday</option>
|
||
<option value="Wednesday">Wednesday</option>
|
||
<option value="Thursday">Thursday</option>
|
||
<option value="Friday">Friday</option>
|
||
<option value="Saturday">Saturday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-report" class="action-panel-label">
|
||
Report format:
|
||
</label>
|
||
<select id="saved-search-report" class="no-border-panel-selector saved-search-report">
|
||
<option value="DocSum">Summary</option>
|
||
<option value="DocSumText">Summary (text)</option>
|
||
<option value="Abstract">Abstract</option>
|
||
<option value="AbstractText">Abstract (text)</option>
|
||
<option value="MEDLINE">PubMed</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-amount" class="action-panel-label">
|
||
Send at most:
|
||
</label>
|
||
<select id="saved-search-amount" class="no-border-panel-selector saved-search-amount">
|
||
<option value="1">1 item</option>
|
||
<option value="5" selected>5 items</option>
|
||
<option value="10">10 items</option>
|
||
<option value="20">20 items</option>
|
||
<option value="50">50 items</option>
|
||
<option value="100">100 items</option>
|
||
<option value="200">200 items</option>
|
||
</select>
|
||
</div>
|
||
<div>
|
||
<input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result">
|
||
<label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox">
|
||
Send even when there aren't any new results
|
||
</label>
|
||
</div>
|
||
<div class="action-panel-control-wrap option-text-in-email-wrap">
|
||
<label for="saved-search-email-text" class="action-panel-label">
|
||
Optional text in email:
|
||
</label>
|
||
<textarea name="saved-search-email-text"
|
||
id="saved-search-email-text"
|
||
class="saved-search-email-text"></textarea>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Save
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your saved search' panel"
|
||
ref="linksrc=close_saved_search_panel"
|
||
aria-controls="saved-search-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Create a file for external citation management software
|
||
</h2>
|
||
<form id="citation-manager-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
|
||
|
||
<input name="results-format" type="hidden" value="pubmed"/>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Send citations to citation manager' panel"
|
||
ref="linksrc=close_citation_manager_panel"
|
||
aria-controls="citation-manager-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your RSS Feed
|
||
</h2>
|
||
|
||
<form id="rss-action-panel-form"
|
||
class="rss-action-panel-form action-panel-content action-form"
|
||
data-create-rss-feed-url="/create-rss-feed-url/"
|
||
data-search-form-term-value="">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="rss-name" class="action-panel-label required-field-asterisk">
|
||
Name of RSS Feed:
|
||
</label>
|
||
<input maxlength="200"
|
||
placeholder="Name"
|
||
type="text"
|
||
name="rss-name"
|
||
id="rss-name"
|
||
class="rss-name"
|
||
value=''
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="rss-limit-wrap">
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="rss-limit" class="action-panel-label">
|
||
Number of items displayed:
|
||
</label>
|
||
<select id="rss-limit" class="no-border-panel-selector rss-limit">
|
||
<option value="5">5</option>
|
||
<option value="10">10</option>
|
||
<option value="15" selected="selected">15</option>
|
||
<option value="20">20</option>
|
||
<option value="50">50</option>
|
||
<option value="100">100</option>
|
||
</select>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Creating..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Create RSS
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your RSS' panel"
|
||
ref="linksrc=close_rss_panel"
|
||
aria-controls="rss-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap rss-link-copy-wrap">
|
||
<label for="rss-link" class="usa-sr-only">RSS Link</label>
|
||
<input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link">
|
||
<button
|
||
type="button"
|
||
disabled
|
||
class="rss-link-copy-button disabled"
|
||
data-ga-category="save_share"
|
||
data-ga-action="rss"
|
||
data-ga-label="copy">
|
||
Copy
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="article-page" id="article-page" data-article-pmid="23150934">
|
||
<aside class="page-sidebar">
|
||
<div class="inner-wrap">
|
||
|
||
<div class="full-text-links">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Full text links
|
||
</h3>
|
||
<div class="full-text-links-list">
|
||
<a class="link-item
|
||
|
||
dialog-focus"
|
||
href="https://www.nejm.org/doi/10.1056/NEJMoa1211851?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub 0www.ncbi.nlm.nih.gov"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=4487&itool=Abstract-def&log$=linkouticon&uid=23150934&db=pubmed&nlmid=0255562"
|
||
title="See full text options at Atypon"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="Atypon"
|
||
data-ga-label="23150934"
|
||
><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--www.nejm.org-pb-assets-images-editorial-icons-nejm-free-full-text.gif" alt="Atypon full text link"><span class="text">
|
||
|
||
Atypon
|
||
|
||
</span></a><a class="link-item
|
||
pmc
|
||
"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/pmid/23150934/"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=True&PrId=3494&itool=Abstract-def&log$=linkouticon&uid=23150934&db=pubmed&nlmid=0255562"
|
||
title="Free full text at PubMed Central"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="PMC"
|
||
data-ga-label="23150934"
|
||
><span class="text">
|
||
|
||
Free PMC article
|
||
|
||
</span></a>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="short-view">
|
||
<a href="#" class="full-text-links-button full-text-links-dialog-trigger">
|
||
Full text links
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger"
|
||
aria-label="Open dialog with citation text in different styles"
|
||
data-ga-category="save_share"
|
||
data-ga-action="cite"
|
||
data-ga-label="open"
|
||
data-all-citations-url="/23150934/citations/"
|
||
data-citation-style="nlm"
|
||
data-pubmed-format-link="/23150934/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="23150934" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger"
|
||
aria-label="Save article in MyNCBI collections."
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_button"
|
||
data-collections-open-dialog-enabled="false"
|
||
data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F23150934%2F%23open-collections-dialog"
|
||
data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog"
|
||
class="dialog collections-dialog"
|
||
aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="2MBaW6UETOEl4wtE5Rc8dNpYcPyYxh04jzlfzWn0tprPYXzuIaPaHVVCKTgaqSyo"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio"
|
||
id="collections-action-dialog-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio"
|
||
id="collections-action-dialog-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label><input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-dialog-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label><select id="collections-action-dialog-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="add">
|
||
Add
|
||
</button><button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger"
|
||
title="Open dialog with more actions to take"
|
||
ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region"><button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title">
|
||
Display options
|
||
</div><div class="content"><div class="format-container"><span class="option-label">
|
||
Format
|
||
</span><select name="format" data-initial-value="abstract" aria-label="Display format" id="sidebar-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div>
|
||
|
||
<div class="social-sharing">
|
||
<h3 class="title">
|
||
Share
|
||
</h3>
|
||
<ul class="social-sharing-links usa-unstyled-list">
|
||
|
||
|
||
<li>
|
||
<a href="http://twitter.com/intent/tweet?text=TREM2%20variants%20in%20Alzheimer%27s%20disease%20https%3A//pubmed.ncbi.nlm.nih.gov/23150934/"
|
||
class="share-link share-link-twitter"
|
||
rel="noreferrer noopener"
|
||
target="Pubmed-Social-Media-Share-Popup"
|
||
title="Share article on Twitter"
|
||
data-ga-category="save_share"
|
||
data-ga-action="social"
|
||
data-ga-label="twitter"></a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.facebook.com/sharer/sharer.php?u=https%3A//pubmed.ncbi.nlm.nih.gov/23150934/"
|
||
class="share-link share-link-facebook"
|
||
rel="noreferrer noopener"
|
||
target="Pubmed-Social-Media-Share-Popup"
|
||
title="Share article on Facebook"
|
||
data-ga-category="save_share"
|
||
data-ga-action="social"
|
||
data-ga-label="fb"></a>
|
||
</li>
|
||
|
||
<li>
|
||
<div class="share-permalink">
|
||
<button class="trigger"
|
||
title="Show article permalink"
|
||
ref="linksrc=show_permalink_btn">
|
||
</button>
|
||
<div class="dropdown" hidden>
|
||
<div class="title">
|
||
Permalink
|
||
</div>
|
||
<div class="content">
|
||
|
||
|
||
<input type="text"
|
||
class="permalink-text"
|
||
value="https://pubmed.ncbi.nlm.nih.gov/23150934/"
|
||
aria-label="Article permalink"/><button class="permalink-copy-button usa-button-primary"
|
||
title="Copy article permalink"
|
||
data-ga-category="save_share"
|
||
data-ga-action="link"
|
||
data-ga-label="copy_link"><span class="button-title">Copy</span></button>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<nav class="page-navigator" role="navigation" aria-label="Page navigation">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Page navigation
|
||
</h3>
|
||
<ul class="items-list">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="heading ">
|
||
<a href="#heading"
|
||
aria-label="navigate to Title & authors section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="heading">
|
||
Title & authors
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
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TREM2 variants in Alzheimer's disease
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||
|
||
|
||
|
||
Affiliations
|
||
|
||
|
||
|
||
<button
|
||
class="more-details"
|
||
id="toggle-authors"
|
||
data-alt-text="Collapse"
|
||
aria-controls="expanded-authors"
|
||
aria-expanded="false"
|
||
data-pinger-ignore
|
||
data-fetch-url="/23150934/long-authors/"
|
||
data-id-prefix="">
|
||
<span class="title">
|
||
Expand
|
||
</span>
|
||
</button>
|
||
|
||
</div>
|
||
|
||
|
||
<div class="extended-article-details" id="expanded-authors" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
<div class="expanded-authors" id="full-view-expanded-authors">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="collaborations">
|
||
<h3 class="title">
|
||
|
||
Collaborators
|
||
|
||
</h3>
|
||
<ul class="group-list">
|
||
|
||
<li>
|
||
|
||
<strong class="title">Alzheimer Genetic Analysis Group</strong>:
|
||
|
||
|
||
|
||
|
||
<div class="authors-list">
|
||
<span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Guerreiro+R"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Rita Guerreiro">Rita Guerreiro</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Wojtas+A"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Aleksandra Wojtas">Aleksandra Wojtas</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Bras+J"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Jose Bras">Jose Bras</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Carrasquillo+M"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Minerva Carrasquillo">Minerva Carrasquillo</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Rogaeva+E"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Ekaterina Rogaeva">Ekaterina Rogaeva</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Majounie+E"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Elisa Majounie">Elisa Majounie</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Cruchaga+C"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Carlos Cruchaga">Carlos Cruchaga</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Sassi+C"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Celeste Sassi">Celeste Sassi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Kauwe+JS"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="John S K Kauwe">John S K Kauwe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Lupton+MK"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Michelle K Lupton">Michelle K Lupton</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Ryten+M"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Mina Ryten">Mina Ryten</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Brown+K"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Kristelle Brown">Kristelle Brown</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Lowe+J"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="James Lowe">James Lowe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Ridge+PG"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Perry G Ridge">Perry G Ridge</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Hammer+MB"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Monia B Hammer">Monia B Hammer</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Wakutani+Y"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Yosuke Wakutani">Yosuke Wakutani</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Hazrati+L"
|
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ref="linksrc=author_name_link"
|
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|
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|
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data-ga-label="Lilinaz Hazrati">Lilinaz Hazrati</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Proitsi+P"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Petroula Proitsi">Petroula Proitsi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Newhouse+S"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Stephen Newhouse">Stephen Newhouse</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Lohmann+E"
|
||
ref="linksrc=author_name_link"
|
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|
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|
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data-ga-label="Ebba Lohmann">Ebba Lohmann</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Erginel-Unaltuna+N"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Nihan Erginel-Unaltuna">Nihan Erginel-Unaltuna</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Medway+C"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Christopher Medway">Christopher Medway</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Hanagasi+H"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Hasmet Hanagasi">Hasmet Hanagasi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Troakes+C"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Claire Troakes">Claire Troakes</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Gurvit+H"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Hakan Gurvit">Hakan Gurvit</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Bilgic+B"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Basar Bilgic">Basar Bilgic</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Al-Sarraj+S"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Safa Al-Sarraj">Safa Al-Sarraj</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Benitez+B"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Bruno Benitez">Bruno Benitez</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Cooper+B"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Breanna Cooper">Breanna Cooper</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Carrell+D"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="David Carrell">David Carrell</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Emre+M"
|
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ref="linksrc=author_name_link"
|
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data-ga-label="Murat Emre">Murat Emre</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Zou+F"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Fanggeng Zou">Fanggeng Zou</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Ma+L"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Li Ma">Li Ma</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Murray+M"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Melissa Murray">Melissa Murray</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Dickson+D"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Dennis Dickson">Dennis Dickson</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Younkin+S"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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|
||
data-ga-label="Steven Younkin">Steven Younkin</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Petersen+RC"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
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|
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data-ga-label="Ronald C Petersen">Ronald C Petersen</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Corcoran+CD"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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|
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data-ga-label="Christopher D Corcoran">Christopher D Corcoran</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Cai+Y"
|
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|
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|
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data-ga-label="Yefei Cai">Yefei Cai</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Oliveira+C"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
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data-ga-label="Catarina Oliveira">Catarina Oliveira</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Ribeiro+MH"
|
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ref="linksrc=author_name_link"
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data-ga-label="Maria Helena Ribeiro">Maria Helena Ribeiro</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Santana+I"
|
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data-ga-label="Isabel Santana">Isabel Santana</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Tschanz+JT"
|
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data-ga-label="JoAnn T Tschanz">JoAnn T Tschanz</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Gibbs+J"
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data-ga-label="J Raphael Gibbs">J Raphael Gibbs</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Norton+MC"
|
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data-ga-label="Maria C Norton">Maria C Norton</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Kloszewska+I"
|
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ref="linksrc=author_name_link"
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data-ga-label="Iwona Kloszewska">Iwona Kloszewska</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Mecocci+P"
|
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data-ga-label="Patrizia Mecocci">Patrizia Mecocci</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Soininen+H"
|
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data-ga-label="Hilkka Soininen">Hilkka Soininen</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Tsolaki+M"
|
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data-ga-label="Magda Tsolaki">Magda Tsolaki</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Vellas+B"
|
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data-ga-label="Bruno Vellas">Bruno Vellas</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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|
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data-ga-label="Ronald G Munger">Ronald G Munger</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Lovestone+S"
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|
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|
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data-ga-label="Jennifer Pocock">Jennifer Pocock</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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|
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data-ga-label="John C Morris">John C Morris</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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|
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|
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data-ga-label="Nick C Fox">Nick C Fox</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Goate+A"
|
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|
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|
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href="/?term=Singleton+A"
|
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href="/?term=Hardy+J"
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|
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|
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data-ga-label="Amy Gerrish">Amy Gerrish</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Chapman+J"
|
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|
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data-ga-label="Jade Chapman">Jade Chapman</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Abraham+R"
|
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href="/?term=Hamshere+M"
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data-ga-label="Marian Hamshere">Marian Hamshere</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Pahwa+JS"
|
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|
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href="/?term=Dowzell+K"
|
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href="/?term=Williams+A"
|
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ref="linksrc=author_name_link"
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data-ga-label="Amy Williams">Amy Williams</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Jones+N"
|
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data-ga-label="Nicola Jones">Nicola Jones</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Thomas+C"
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data-ga-label="Charlene Thomas">Charlene Thomas</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Stretton+A"
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data-ga-label="Alexandra Stretton">Alexandra Stretton</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Morgan+A"
|
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ref="linksrc=author_name_link"
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data-ga-label="Angharad Morgan">Angharad Morgan</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Williams+K"
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ref="linksrc=author_name_link"
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data-ga-label="Kate Williams">Kate Williams</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Thomas+S"
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ref="linksrc=author_name_link"
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data-ga-label="Sophie Thomas">Sophie Thomas</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Brayne+C"
|
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data-ga-label="Carol Brayne">Carol Brayne</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Rubinsztein+DC"
|
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data-ga-label="David C Rubinsztein">David C Rubinsztein</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Gill+M"
|
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data-ga-label="Michael Gill">Michael Gill</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Lawlor+B"
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data-ga-label="Brian Lawlor">Brian Lawlor</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Lynch+A"
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data-ga-label="Aoibhinn Lynch">Aoibhinn Lynch</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Passmore+P"
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href="/?term=Craig+D"
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href="/?term=Johnston+JA"
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data-ga-label="Celeste Sassi">Celeste Sassi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Kauwe+JS&cauthor_id=23150934"
|
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data-ga-label="John S K Kauwe">John S K Kauwe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Younkin+S&cauthor_id=23150934"
|
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data-ga-label="Steven Younkin">Steven Younkin</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Hazrati+L&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
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|
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data-ga-label="Lilinaz Hazrati">Lilinaz Hazrati</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Collinge+J&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-category="search"
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|
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data-ga-label="John Collinge">John Collinge</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Pocock+J&cauthor_id=23150934"
|
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data-ga-label="Jennifer Pocock">Jennifer Pocock</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Lashley+T&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-label="Tammaryn Lashley">Tammaryn Lashley</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Williams+J&cauthor_id=23150934"
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data-ga-label="Julie Williams">Julie Williams</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Lambert+JC&cauthor_id=23150934"
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data-ga-label="Jean-Charles Lambert">Jean-Charles Lambert</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Amouyel+P&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-category="search"
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|
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data-ga-label="Philippe Amouyel">Philippe Amouyel</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Goate+A&cauthor_id=23150934"
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data-ga-label="Alison Goate">Alison Goate</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Rademakers+R&cauthor_id=23150934"
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ref="linksrc=author_name_link"
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data-ga-category="search"
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data-ga-label="Rosa Rademakers">Rosa Rademakers</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Morgan+K&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-label="Kevin Morgan">Kevin Morgan</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Powell+J&cauthor_id=23150934"
|
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data-ga-label="John Powell">John Powell</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=St+George-Hyslop+P&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-label="Peter St George-Hyslop">Peter St George-Hyslop</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Singleton+A&cauthor_id=23150934"
|
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ref="linksrc=author_name_link"
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data-ga-label="Andrew Singleton">Andrew Singleton</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Hardy+J&cauthor_id=23150934"
|
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data-ga-label="John Hardy">John Hardy</a><span class="semicolon">; </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Alzheimer+Genetic+Analysis+Group%5BCorporate+Author%5D"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Alzheimer Genetic Analysis Group">Alzheimer Genetic Analysis Group</a></span>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="collaborations">
|
||
<h3 class="title">
|
||
|
||
Collaborators
|
||
|
||
</h3>
|
||
<ul class="group-list">
|
||
|
||
<li>
|
||
|
||
<strong class="title">Alzheimer Genetic Analysis Group</strong>:
|
||
|
||
|
||
|
||
|
||
<div class="authors-list">
|
||
<span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Guerreiro+R"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Rita Guerreiro">Rita Guerreiro</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Wojtas+A"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Aleksandra Wojtas">Aleksandra Wojtas</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Bras+J"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Jose Bras">Jose Bras</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Carrasquillo+M"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Minerva Carrasquillo">Minerva Carrasquillo</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Rogaeva+E"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Ekaterina Rogaeva">Ekaterina Rogaeva</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Majounie+E"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Elisa Majounie">Elisa Majounie</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Cruchaga+C"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Carlos Cruchaga">Carlos Cruchaga</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Sassi+C"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Celeste Sassi">Celeste Sassi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Kauwe+JS"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="John S K Kauwe">John S K Kauwe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Lupton+MK"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Michelle K Lupton">Michelle K Lupton</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Ryten+M"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Mina Ryten">Mina Ryten</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Brown+K"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Kristelle Brown">Kristelle Brown</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Lowe+J"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="James Lowe">James Lowe</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Ridge+PG"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Perry G Ridge">Perry G Ridge</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Hammer+MB"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Monia B Hammer">Monia B Hammer</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Wakutani+Y"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Yosuke Wakutani">Yosuke Wakutani</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Hazrati+L"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Lilinaz Hazrati">Lilinaz Hazrati</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Proitsi+P"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Petroula Proitsi">Petroula Proitsi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Newhouse+S"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Stephen Newhouse">Stephen Newhouse</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Lohmann+E"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Ebba Lohmann">Ebba Lohmann</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Erginel-Unaltuna+N"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Nihan Erginel-Unaltuna">Nihan Erginel-Unaltuna</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Medway+C"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
||
data-ga-action="author_link"
|
||
data-ga-label="Christopher Medway">Christopher Medway</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Hanagasi+H"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
||
data-ga-label="Hasmet Hanagasi">Hasmet Hanagasi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Troakes+C"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Claire Troakes">Claire Troakes</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Gurvit+H"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Hakan Gurvit">Hakan Gurvit</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Bilgic+B"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Basar Bilgic">Basar Bilgic</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Al-Sarraj+S"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Safa Al-Sarraj">Safa Al-Sarraj</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Benitez+B"
|
||
ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Bruno Benitez">Bruno Benitez</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
||
href="/?term=Cooper+B"
|
||
ref="linksrc=author_name_link"
|
||
data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Breanna Cooper">Breanna Cooper</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Carrell+D"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="David Carrell">David Carrell</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Emre+M"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Murat Emre">Murat Emre</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Zou+F"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Fanggeng Zou">Fanggeng Zou</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Ma+L"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-action="author_link"
|
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data-ga-label="Li Ma">Li Ma</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Murray+M"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
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data-ga-label="Melissa Murray">Melissa Murray</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Dickson+D"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
|
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data-ga-label="Dennis Dickson">Dennis Dickson</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Younkin+S"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
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data-ga-label="Steven Younkin">Steven Younkin</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Petersen+RC"
|
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ref="linksrc=author_name_link"
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data-ga-category="search"
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data-ga-label="Ronald C Petersen">Ronald C Petersen</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Corcoran+CD"
|
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ref="linksrc=author_name_link"
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data-ga-label="Christopher D Corcoran">Christopher D Corcoran</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Cai+Y"
|
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ref="linksrc=author_name_link"
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data-ga-category="search"
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data-ga-label="Yefei Cai">Yefei Cai</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Oliveira+C"
|
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ref="linksrc=author_name_link"
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data-ga-category="search"
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data-ga-label="Catarina Oliveira">Catarina Oliveira</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Ribeiro+MH"
|
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ref="linksrc=author_name_link"
|
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data-ga-category="search"
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data-ga-label="Maria Helena Ribeiro">Maria Helena Ribeiro</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
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href="/?term=Santana+I"
|
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ref="linksrc=author_name_link"
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data-ga-label="Isabel Santana">Isabel Santana</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name"
|
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href="/?term=Tschanz+JT"
|
||
ref="linksrc=author_name_link"
|
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Affiliation
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<li data-affiliation-id="short-view-affiliation-1"
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><sup class="key">1</sup> University College London (UCL) Institute of Neurology, London, United Kingdom.</li>
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<span class="identifier pubmed">
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PMID:
|
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</span>
|
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|
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<strong class="current-id" title="PubMed ID">23150934</strong>
|
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DOI:
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|
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Abstract
|
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|
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|
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id="eng-abstract">
|
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|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Background:
|
||
</strong>
|
||
|
||
Homozygous loss-of-function mutations in TREM2, encoding the triggering receptor expressed on myeloid cells 2 protein, have previously been associated with an autosomal recessive form of early-onset dementia.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Methods:
|
||
</strong>
|
||
|
||
We used genome, exome, and Sanger sequencing to analyze the genetic variability in TREM2 in a series of 1092 patients with Alzheimer's disease and 1107 controls (the discovery set). We then performed a meta-analysis on imputed data for the TREM2 variant rs75932628 (predicted to cause a R47H substitution) from three genomewide association studies of Alzheimer's disease and tested for the association of the variant with disease. We genotyped the R47H variant in an additional 1887 cases and 4061 controls. We then assayed the expression of TREM2 across different regions of the human brain and identified genes that are differentially expressed in a mouse model of Alzheimer's disease and in control mice.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Results:
|
||
</strong>
|
||
|
||
We found significantly more variants in exon 2 of TREM2 in patients with Alzheimer's disease than in controls in the discovery set (P=0.02). There were 22 variant alleles in 1092 patients with Alzheimer's disease and 5 variant alleles in 1107 controls (P<0.001). The most commonly associated variant, rs75932628 (encoding R47H), showed highly significant association with Alzheimer's disease (P<0.001). Meta-analysis of rs75932628 genotypes imputed from genomewide association studies confirmed this association (P=0.002), as did direct genotyping of an additional series of 1887 patients with Alzheimer's disease and 4061 controls (P<0.001). Trem2 expression differed between control mice and a mouse model of Alzheimer's disease.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Conclusions:
|
||
</strong>
|
||
|
||
Heterozygous rare variants in TREM2 are associated with a significant increase in the risk of Alzheimer's disease. (Funded by Alzheimer's Research UK and others.).
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
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|
||
</div>
|
||
|
||
|
||
|
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|
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|
||
|
||
|
||
<p class="disclaimer" id="disclaimer">
|
||
<a href="/disclaimer/" target="_blank" data-ga-category="literature_resources"
|
||
data-ga-action="disclaimer_link" data-ga-label="under_abstract">PubMed Disclaimer</a>
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="figures" id="figures">
|
||
<h2 class="title">
|
||
Figures
|
||
</h2>
|
||
|
||
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||
itemscope itemtype="http://schema.org/ImageGallery">
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href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7057/3631573/2b331dc0744e/nihms-448530-f0001.jpg"
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|
||
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||
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|
||
data-image-width="561"
|
||
data-image-height="599"
|
||
data-image-alt="Figure 1"
|
||
data-pmc-id="PMC3631573"
|
||
data-figure-id="F1">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-0"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7057/3631573/6160a7f30efc/nihms-448530-f0001.gif"
|
||
alt="Figure 1" />
|
||
</a>
|
||
|
||
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||
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||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> Figure 1. Pathological Hallmarks in Carriers of… </p>
|
||
</strong>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> Figure 1. Pathological Hallmarks in Carriers of <i> TREM2 </i> Variants </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Shown are pathological findings in samples… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-0" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
Figure 1. Pathological Hallmarks in Carriers of <i>TREM2</i> Variants
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Shown are pathological findings in samples containing variant D87N (Panels A through D) and variant R47H (Panels E through L) obtained from patients with Alzheimer's disease. A carrier of the D87N variant had mature plaques (Panel A, arrow), along with more diffuse plaques and a moderate degree of cerebral amyloid angiopathy (Panel B). Beta amyloid was found deposited in leptomeningeal blood vessels. Tau immunohistochemical analysis revealed neuritic plaques (Panel C) in the hippocampus and numerous neurofibrillary tangles throughout the cortical regions (Panel D). Two carriers of the R47H variant also showed pathological features of Alzheimer's disease (with sections obtained from one patient in Panels E through H and from the other in Panels I through L) in the form of mature and diffuse plaques (Panels E and J, arrow). Severe cerebral amyloid angiopathy was evident with the presence of parenchymal capillary involvement (Panel F) and circumferential deposition of beta amyloid (Panel K). Also present were neuritic plaques (Panels G and L, arrow in Panel L), neurofibrillary tangles (Panels H and L), and abundant neuropil threads. However, one carrier of the R47H variant showed only moderate cerebral amyloid angiopathy with no other pathological abnormalities (Panel I, inset). Immunohistochemical analysis was carried out with the use of antibodies against beta amyloid (DAKO; 1:100) to identify the beta amyloid protein in both plaques and cerebral amyloid angiopathy, and AT8 antibody (Autogen Bioclear; 1:600) to identify tau.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
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<figure class="figure-item "
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<a class="figure-link"
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href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7057/3631573/df755439fe69/nihms-448530-f0002.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-1"
|
||
role="button"
|
||
data-image-width="600"
|
||
data-image-height="224"
|
||
data-image-alt="Figure 2"
|
||
data-pmc-id="PMC3631573"
|
||
data-figure-id="F2">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-1"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7057/3631573/b3c89ee9714f/nihms-448530-f0002.gif"
|
||
alt="Figure 2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="600">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="224">
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||
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||
|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> Figure 2. Immunohistochemical Analyses of <i> Trem2 </i> in… </p>
|
||
</strong>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> Figure 2. Immunohistochemical Analyses of <i> Trem2 </i> in TgCRND8 Mice </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Slides of samples from TgCRND8 mice… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-1" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
Figure 2. Immunohistochemical Analyses of <i>Trem2</i> in TgCRND8 Mice
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Slides of samples from TgCRND8 mice (a transgenic mouse model of Alzheimer's disease) and age-matched littermates (controls) at different ages show that <i>Trem2</i> is expressed as small granules in the cytoplasm of neurons (arrowheads) in both the transgenic mice and controls. In a slide of a sample from a transgenic mouse, the amyloid plaques are also surrounded by Trem2-positive granules (Panel D, arrow), and the Trem2 granules increase in number and size, as compared with the controls. The scale bar represents 30 mm in Panels A, B, C, E, and F and 60 mm in Panel D.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<!-- Root element of PhotoSwipe. Must have class pswp. -->
|
||
<div class="pswp figures-dialog" id="figures-dialog" tabindex="-1" role="dialog" aria-hidden="true"
|
||
data-image-gallery-uid="article-figures" aria-label="Figures Dialog">
|
||
<!-- Background of PhotoSwipe.
|
||
It's a separate element as animating opacity is faster than rgba(). -->
|
||
<div class="pswp__bg"></div>
|
||
|
||
<!-- Slides wrapper with overflow:hidden. -->
|
||
<div class="pswp__scroll-wrap">
|
||
<!-- Container that holds slides.
|
||
PhotoSwipe keeps only 3 of them in the DOM to save memory.
|
||
Don't modify these 3 pswp__item elements, data is added later on. -->
|
||
<div class="pswp__container">
|
||
<div class="pswp__item"></div>
|
||
<div class="pswp__item"></div>
|
||
<div class="pswp__item"></div>
|
||
</div>
|
||
|
||
<!-- Default (PhotoSwipeUI_Default) interface on top of sliding area. Can be changed. -->
|
||
<div class="pswp__ui pswp__ui--hidden">
|
||
<div class="pswp__top-bar">
|
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<!-- Controls are self-explanatory. Order can be changed. -->
|
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<div class="pswp__counter"></div>
|
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<button class="pswp__button pswp__button--close" title="Close (Esc)"></button>
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<button class="pswp__button pswp__button--share" title="Share"></button>
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|
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<div class="pswp__preloader">
|
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|
||
<div class="pswp__preloader__cut">
|
||
<div class="pswp__preloader__donut"></div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
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|
||
<div class="pswp__share-modal pswp__share-modal--hidden pswp__single-tap">
|
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<div class="pswp__share-tooltip"></div>
|
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</div>
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<button class="pswp__button pswp__button--arrow--left" title="Previous (arrow left)">
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|
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|
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</div>
|
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</div>
|
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|
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<div class="figure-dialog-caption">
|
||
<div class="figure-caption-link-container">
|
||
<a class="figure-caption-link" href="#">See this image and copyright information in PMC</a>
|
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|
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<div class="figure-caption-center"
|
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data-expand-title="click to show full caption"
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|
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|
||
|
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|
||
|
||
|
||
|
||
<div class="linked-articles" id="linked-commentary">
|
||
<h2 class="title">
|
||
Comment in
|
||
</h2>
|
||
<ul class="item-list usa-unstyled-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/23151315/"
|
||
ref="article_id=23151315&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary">
|
||
|
||
Variant TREM2 as risk factor for Alzheimer's disease.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Neumann H, Daly MJ.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Neumann H, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">N Engl J Med. 2013 Jan 10;368(2):182-4. doi: 10.1056/NEJMe1213157. Epub 2012 Nov 14.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">N Engl J Med. 2013.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">23151315</span></span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/23208114/"
|
||
ref="article_id=23208114&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary">
|
||
|
||
Alzheimer disease: TREM2 linked to late-onset AD.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Jones B.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Jones B.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Nat Rev Neurol. 2013 Jan;9(1):5. doi: 10.1038/nrneurol.2012.254. Epub 2012 Dec 4.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Nat Rev Neurol. 2013.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">23208114</span></span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/23347262/"
|
||
ref="article_id=23347262&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary">
|
||
|
||
TREM2: a new risk factor for Alzheimer's disease.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Singaraja RR.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Singaraja RR.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Clin Genet. 2013 Jun;83(6):525-6. doi: 10.1111/cge.12108.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Clin Genet. 2013.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">23347262</span></span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/24131184/"
|
||
ref="article_id=24131184&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary">
|
||
|
||
TREM2 and neurodegenerative disease.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Reitz C, Mayeux R; Alzheimer’s Disease Genetics Consortium.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Reitz C, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">N Engl J Med. 2013 Oct 17;369(16):1564-5. doi: 10.1056/NEJMc1306509.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">N Engl J Med. 2013.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">24131184</span></span>
|
||
<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/24131185/"
|
||
ref="article_id=24131185&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary">
|
||
|
||
TREM2 and neurodegenerative disease.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Bertram L, Parrado AR, Tanzi RE.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Bertram L, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">N Engl J Med. 2013 Oct 17;369(16):1565. doi: 10.1056/NEJMc1306509.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">N Engl J Med. 2013.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">24131185</span></span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
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|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/24131188/"
|
||
ref="article_id=24131188&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
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data-ga-action="abstract_page_link"
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|
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|
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|
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<span class="docsum-authors full-authors">Shinohara M, Kikuchi M, Onishi-Takeya M, Tashiro Y, Suzuki K, Noda Y, Takeda S, Mukouzono M, Nagano S, Fukumori A, Morishita R, Nakaya A, Sato N.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Shinohara M, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">FASEB Bioadv. 2021 Mar 2;3(5):323-333. doi: 10.1096/fba.2020-00151. eCollection 2021 May.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">FASEB Bioadv. 2021.</span>
|
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|
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|
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<span class="citation-part">PMID: <span class="docsum-pmid">33977233</span></span>
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<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
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Goate A, Chartier-Harlin MC, Mullan M, et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 1991;349:704–6.
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Rogaev EI, Sherrington R, Rogaeva EA, et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature. 1995;376:775–8.
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Sherrington R, Rogaev EI, Liang Y, et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature. 1995;375:754–60.
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Strittmatter WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A. 1993;90:1977–81.
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ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Alzheimer+Disease"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Alzheimer Disease / genetics*">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Alzheimer Disease/genetics"[MAJR]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Alzheimer Disease/genetics"[MAJR]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Alzheimer Disease / pathology"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-2"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Alzheimer Disease / pathology
|
||
</button><div id="keyword-actions-mesh-terms-2"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Alzheimer Disease / pathology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Alzheimer+Disease%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Alzheimer+Disease%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Alzheimer Disease/pathology"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Alzheimer Disease / pathology">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Alzheimer+Disease"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Alzheimer Disease / pathology">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Alzheimer Disease/pathology"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Alzheimer Disease/pathology"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Animals"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-3"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Animals
|
||
</button><div id="keyword-actions-mesh-terms-3"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Animals"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Animals%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Animals%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Animals"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Animals">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Animals"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Animals">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Animals"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Animals"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Brain / pathology"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-4"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Brain / pathology
|
||
</button><div id="keyword-actions-mesh-terms-4"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Brain / pathology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Brain%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Brain%2Fpathology%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Brain/pathology"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Brain / pathology">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Brain"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Brain / pathology">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Brain/pathology"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Brain/pathology"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Exome / genetics"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-5"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Exome / genetics
|
||
</button><div id="keyword-actions-mesh-terms-5"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Exome / genetics"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Exome%2Fgenetics%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Exome%2Fgenetics%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Exome/genetics"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Exome / genetics">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Exome"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Exome / genetics">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Exome/genetics"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Exome/genetics"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Genetic Variation"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-6"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Genetic Variation
|
||
</button><div id="keyword-actions-mesh-terms-6"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Genetic Variation"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Genetic+Variation%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Genetic+Variation%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Genetic Variation"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Genetic Variation">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Genetic+Variation"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Genetic Variation">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Genetic Variation"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Genetic Variation"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Genome-Wide Association Study"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-7"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Genome-Wide Association Study
|
||
</button><div id="keyword-actions-mesh-terms-7"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Genome-Wide Association Study"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Genome-Wide+Association+Study%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Genome-Wide+Association+Study%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Genome-Wide Association Study"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Genome-Wide Association Study">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Genome-Wide+Association+Study"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Genome-Wide Association Study">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Genome-Wide Association Study"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Genome-Wide Association Study"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Genotype"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-8"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Genotype
|
||
</button><div id="keyword-actions-mesh-terms-8"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Genotype"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Genotype%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Genotype%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Genotype"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Genotype">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Genotype"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Genotype">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Genotype"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Genotype"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Genotyping Techniques"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-9"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Genotyping Techniques
|
||
</button><div id="keyword-actions-mesh-terms-9"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Genotyping Techniques"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Genotyping+Techniques%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Genotyping+Techniques%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Genotyping Techniques"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Genotyping Techniques">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Genotyping+Techniques"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Genotyping Techniques">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Genotyping Techniques"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Genotyping Techniques"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Heterozygote"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-10"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Heterozygote
|
||
</button><div id="keyword-actions-mesh-terms-10"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Heterozygote"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Heterozygote%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Heterozygote%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Heterozygote"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Heterozygote">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Heterozygote"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Heterozygote">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Heterozygote"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Heterozygote"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Humans"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-11"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Humans
|
||
</button><div id="keyword-actions-mesh-terms-11"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Humans"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Humans"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="mesh_term"
|
||
data-ga-label="Humans">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Humans"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Humans">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Humans"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Humans"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
|
||
aria-label="Toggle dropdown menu for keyword Membrane Glycoproteins / genetics*"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-major-12"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Membrane Glycoproteins / genetics*
|
||
</button><div id="keyword-actions-mesh-terms-major-12"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Membrane Glycoproteins / genetics*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
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Membrane Glycoproteins / metabolism
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<div id="substances" class="substances keywords-section">
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<h2 class="title">
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Substances
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href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Membrane+Glycoproteins%22"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Membrane Glycoproteins"[nm]"
|
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data-ga-label=""Membrane Glycoproteins"[nm]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword RNA, Messenger"
|
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tabindex="0"
|
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|
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aria-expanded="false"
|
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data-pinger-ignore>
|
||
RNA, Messenger
|
||
</button><div id="keyword-actions-substances-1"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
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aria-label="Dropdown menu for keyword RNA, Messenger"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Receptors, Immunologic
|
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</button><div id="keyword-actions-substances-2"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Receptors, Immunologic"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
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TREM2 protein, human
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</button><div id="keyword-actions-substances-3"
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hidden
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</div>
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|
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|
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<div id="related-links" class="related-links">
|
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<h2 class="title">
|
||
Related information
|
||
</h2>
|
||
|
||
<ul class="related-links-list"><li><a title="PubMed links associated with Books" href="https://www.ncbi.nlm.nih.gov/books?linkname=pubmed_books_refs&from_uid=23150934"
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ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=1">
|
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Cited in Books
|
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</a></li><li><a title="Clinical variations associated with publication" href="https://www.ncbi.nlm.nih.gov/clinvar?linkname=pubmed_clinvar&from_uid=23150934"
|
||
ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=2">
|
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ClinVar
|
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</a></li><li><a title="Link to related Genes" href="https://www.ncbi.nlm.nih.gov/gene?linkname=pubmed_gene&from_uid=23150934"
|
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ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=3">
|
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Gene
|
||
</a></li><li><a title="Link to Gene for the GeneRIF subcategory" href="https://www.ncbi.nlm.nih.gov/gene?linkname=pubmed_gene_rif&from_uid=23150934"
|
||
ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=4">
|
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Gene (GeneRIF)
|
||
</a></li><li><a title="Related information in MedGen" href="https://www.ncbi.nlm.nih.gov/medgen?linkname=pubmed_medgen&from_uid=23150934"
|
||
ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=5">
|
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MedGen
|
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</a></li><li><a title="Related records in MedGen based on citations in GeneReviews and Medical Genetics Summaries" href="https://www.ncbi.nlm.nih.gov/medgen?linkname=pubmed_medgen_bookshelf_cited&from_uid=23150934"
|
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ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=6">
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MedGen (Bookshelf cited)
|
||
</a></li><li><a title="OMIM (cited) Links" href="https://www.ncbi.nlm.nih.gov/omim?linkname=pubmed_omim_cited&from_uid=23150934"
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ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=7">
|
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OMIM (cited)
|
||
</a></li><li><a title="Link to Protein RefSeqs" href="https://www.ncbi.nlm.nih.gov/protein?linkname=pubmed_protein_refseq&from_uid=23150934"
|
||
ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=8">
|
||
Protein (RefSeq)
|
||
</a></li><li><a title="PubMed to SNP links" href="https://www.ncbi.nlm.nih.gov/snp?linkname=pubmed_snp&from_uid=23150934"
|
||
ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=23150934&ordinalpos=1&linkpos=9">
|
||
SNP
|
||
</a></li></ul>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
<div id="grants" class="grants">
|
||
<h2 class="title">
|
||
Grants and funding
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