118 lines
55 KiB
HTML
118 lines
55 KiB
HTML
<!DOCTYPE html>
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/*# sourceURL=/css/ampshared.css*/</style><meta property="og:locale" content="en_US"><meta property="og:type" content="article"><meta property="og:title" content="RefSeq Release 221 - NCBI Insights"><meta property="og:description" content="RefSeq release 221 is now available online and from the FTP site. You can access RefSeq data through NCBI Datasets. What’s included in this release? As of November 6, 2023, this full release incorporates genomic, transcript, and protein data containing: 404,657,610 records 300,054,945 proteins 57,882,313 RNAs sequences from 143,819 organisms The release is provided in several directories as a … Continue reading RefSeq Release 221 →"><meta property="og:url" content="https://ncbiinsights.ncbi.nlm.nih.gov/2023/11/14/refseq-release-221/"><meta property="og:site_name" content="NCBI Insights"><meta property="article:publisher" content="https://www.facebook.com/ncbi.nlm"><meta property="article:published_time" content="2023-11-14T16:28:48+00:00"><meta property="og:image" content="https://ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2023/11/iStock-1478808572-e1699973751452.jpg"><meta property="og:image:width" content="1100"><meta property="og:image:height" content="733"><meta property="og:image:type" content="image/jpeg"><meta name="author" content="NCBI Staff"><meta name="twitter:card" content="summary_large_image"><meta name="twitter:creator" content="@NCBI"><meta name="twitter:site" content="@NCBI"><meta name="twitter:label1" content="Written by"><meta name="twitter:data1" content="NCBI Staff"><meta name="twitter:label2" content="Est. reading time"><meta name="twitter:data2" content="2 minutes"><meta name="robots" content="index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1"><meta name="generator" content="AMP Plugin v2.5.5; mode=reader; theme=legacy"><script async="" src="https://cdn.ampproject.org/v0.mjs" type="module" crossorigin="anonymous"></script><script async nomodule src="https://cdn.ampproject.org/v0.js" crossorigin="anonymous"></script><script src="https://cdn.ampproject.org/v0/amp-social-share-0.1.mjs" async="" custom-element="amp-social-share" type="module" crossorigin="anonymous"></script><script async nomodule src="https://cdn.ampproject.org/v0/amp-social-share-0.1.js" crossorigin="anonymous" custom-element="amp-social-share"></script><style 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<h1 class="amp-wp-title">RefSeq Release 221</h1>
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<time datetime="2023-11-14T16:28:48+00:00">
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1 year ago </time>
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<figure class="amp-wp-article-featured-image wp-caption">
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<amp-img width="1024" height="683" src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2023/11/iStock-1478808572-e1699973751452.jpg?fit=1024%2C683&ssl=1" class="attachment-large size-large wp-post-image amp-wp-enforced-sizes i-amphtml-layout-intrinsic i-amphtml-layout-size-defined" alt="Image of a Mongolian gerbil and a piece of wood." data-hero-candidate="" layout="intrinsic" data-hero i-amphtml-ssr i-amphtml-layout="intrinsic"><i-amphtml-sizer slot="i-amphtml-svc" class="i-amphtml-sizer"><img alt="" aria-hidden="true" class="i-amphtml-intrinsic-sizer" role="presentation" src="data:image/svg+xml;base64,PHN2ZyBoZWlnaHQ9IjY4MyIgd2lkdGg9IjEwMjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyIgdmVyc2lvbj0iMS4xIi8+"></i-amphtml-sizer><img class="i-amphtml-fill-content i-amphtml-replaced-content" decoding="async" loading="lazy" alt="Image of a Mongolian gerbil and a piece of wood." src="https://i0.wp.com/ncbiinsights.ncbi.nlm.nih.gov/wp-content/uploads/2023/11/iStock-1478808572-e1699973751452.jpg?fit=1024%2C683&ssl=1"></amp-img> <p class="wp-caption-text">
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Mongolian gerbil. Maintenance and care of exotic pets </p>
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</figure>
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<div class="amp-wp-article-content">
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<p>RefSeq release 221 is now available <a href="https://www.ncbi.nlm.nih.gov/refseq/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">online</a> and from the <a href="https://ftp.ncbi.nlm.nih.gov/refseq/release/">FTP</a> site. You can access RefSeq data through <a href="https://www.ncbi.nlm.nih.gov/datasets/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">NCBI Datasets</a>.</p>
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<h5>What’s included in this release?</h5>
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<p>As of November 6, 2023, this full release incorporates genomic, transcript, and protein data containing:</p>
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<ul>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">404,657,610 records</span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">300,054,945 proteins</span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">57,882,313 RNAs</span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">sequences from 143,819 organisms </span></li>
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</ul>
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<p></p>
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<p>The release is provided in several directories as a complete dataset and divided by logical groupings.</p>
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<h5>Human genome annotation update</h5>
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<h6>Assembly GRCh38.p14</h6>
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<ul>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Annotation Release <a href="https://www.ncbi.nlm.nih.gov/genome/annotation_euk/Homo_sapiens/GCF_000001405.40-RS_2023_10/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_000001405.40-RS_2023_10</a> is an update of NCBI Homo sapiens Annotation Release 110, incorporating the latest set of curated RefSeq transcript changes.</span></li>
|
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">The annotation products are available in the sequence databases and on the <a href="https://ftp.ncbi.nlm.nih.gov/genomes/all/annotation_releases/9606/GCF_000001405.40-RS_2023_10/">FTP site</a>.</span></li>
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</ul>
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<h6>Assembly T2T-CHM13v2.0</h6>
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<ul>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Annotation Release <a href="https://www.ncbi.nlm.nih.gov/genome/annotation_euk/Homo_sapiens/GCF_009914755.1-RS_2023_10/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_009914755.1-RS_2023_10</a> is an update of NCBI Homo sapiens Annotation Release 110, incorporating the latest set of curated RefSeq transcript changes.</span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">The annotation products are available in the sequence databases and on the <a href="https://ftp.ncbi.nlm.nih.gov/genomes/all/annotation_releases/9606/GCF_009914755.1-RS_2023_10/">FTP site</a>.</span><br>
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<b data-amp-original-style="font-family: Merriweather; font-size: 1rem;" class="amp-wp-2d14dbd"></b></li>
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</ul>
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<h5>New eukaryotic genome annotations</h5>
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<p>This release includes new annotations generated by NCBI’s eukaryotic genome annotation pipeline for 36 additional species, including:</p>
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<ul>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Cow, based on updated assembly ARS-UCD2.0 (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_002263795.3/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_002263795.3_2023_09</a>) </span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Mongolian gerbil, based on new assembly Bangor_MerUng_6.1 (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_030254825.1/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_030254825.1_2023_10</a>) <em>(pictured)</em></span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Common lizard, based on new assembly Bangor_MerUng_6.1 (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_963506605.1/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_963506605.1_2023_10</a>)</span></li>
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||
<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">House finch, based on new assembly bHaeMex1.pri (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_027477595.1/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_027477595.1_2023_09</a>) </span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Wine grape, based on new assembly ASM3070453v1 (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_030704535.1/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_030704535.1_2023_09</a>) </span></li>
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<li><span data-amp-original-style="font-size: 17px;" class="amp-wp-8bdd01f">Sweet potato weevil, based on new assembly icCylForm1.1 (<a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_029955315.1/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231114">GCF_029955315.1_2023_10</a>) </span></li>
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</ul>
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<h5><b>Future changes</b></h5>
|
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<p>We plan to rename the *.nonredundant_protein* files to clarify that the files are specific to the prokaryote WP protein dataset. You should continue to use all complete.*protein.* files if you wish to obtain a complete set of RefSeq proteins across all represented taxa.</p>
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<h4>Stay up to date</h4>
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<p>RefSeq is part of the <a href="https://www.ncbi.nlm.nih.gov/comparative-genomics-resource/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=refseq-release-221-20231113">NIH Comparative Genomics Resource (CGR)</a>. <span data-contrast="none">CGR facilitates reliable comparative genomics analyses for all eukaryotic organisms through an NCBI Toolkit and community collaboration. </span><span class="TextRun Highlight SCXW148001688 BCX8" lang="EN-US" data-contrast="none"><span class="NormalTextRun SCXW148001688 BCX8">Follow us on social </span></span><a class="Hyperlink SCXW148001688 BCX8" href="https://twitter.com/ncbi" target="_blank" rel="noreferrer noopener"><span class="TextRun Highlight SCXW148001688 BCX8" lang="EN-US" data-contrast="none"><span class="NormalTextRun SCXW148001688 BCX8" data-ccp-charstyle="Hyperlink">@NCBI</span></span></a> and <a class="external-link" href="https://public.govdelivery.com/accounts/USNLMOCPL/subscriber/new?topic_id=USNLMOCPL_50%22" rel="nofollow">join our mailing list</a> to keep up to date with RefSeq and other CGR news.</p>
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<h4>Questions?</h4>
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<p><span data-contrast="auto">If you have questions or would like to provide feedback, please <a href="https://support.nlm.nih.gov/support/create-case/">reach out</a> to us!</span><span data-contrast="auto"> </span></p>
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