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<span>Uric Acid Test</span>
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<span class="page-url print-only">URL of this page: https://medlineplus.gov/lab-tests/uric-acid-test/</span>
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<h1>Uric Acid Test</h1>
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<section><div class="mp-content"><h2>What is a uric acid test?</h2>
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<p>This test measures the amount of uric acid in a sample of your blood or urine (pee). Uric acid is a normal waste product that your body makes when it breaks down chemicals called purines. Purines come from your cells when they die. Purines are also found in many foods and beverages.</p>
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<p>Most uric acid dissolves in your blood. Your kidneys filter the uric acid out of your blood, and it leaves your body in your urine. If uric acid builds up in your blood, it can form needle-shaped crystals in and around your joints. This condition is called <a data-tid="264" href="https://medlineplus.gov/gout.html">gout</a>.</p>
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<p>Gout is a type of <a data-tid="23" href="https://medlineplus.gov/arthritis.html">arthritis</a> that causes painful swelling in your joints. High uric acid levels can also cause <a data-tid="1224" href="https://medlineplus.gov/kidneystones.html">kidney stones</a>, or <a data-tid="302" href="https://medlineplus.gov/kidneyfailure.html">kidney failure</a>. But not everyone with high levels of uric acid will have these problems.</p>
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<p>Other names: serum urate, UA, uric acid: serum and urine</p></div>
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</section>
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<section><div class="mp-content"><h2>What is it used for?</h2>
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<p>A uric acid blood test may be used to:</p>
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<ul>
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<li>Help diagnose gout, usually when done with a <a data-pid="13181" href="https://medlineplus.gov/lab-tests/synovial-fluid-analysis/">synovial fluid analysis</a>.</li>
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<li>Monitor uric acid levels in people who are having <a data-tid="464" href="https://medlineplus.gov/cancerchemotherapy.html">cancer chemotherapy</a> or certain other <a data-tid="25" href="https://medlineplus.gov/cancer.html">cancer</a> treatments. When treatment kills cancer cells quickly, they release large amounts of purines into the blood. This can lead to serious problems from high uric acid levels. Testing helps catch an increase in uric acid so it can be treated early.</li>
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</ul>
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<p>A uric acid urine test may be used to:</p>
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<ul>
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<li>Help find out whether high levels of uric acid are causing kidney stones</li>
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<li>Monitor the risk of developing kidney stones in people who have gout</li>
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</ul></div>
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</section>
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<section><div class="mp-content"><h2>Why do I need a uric acid test?</h2>
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<p>You may need a uric acid blood test if you:</p>
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<ul>
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<li>Have symptoms of gout. Symptoms usually happen in one joint at a time. The big toe is most commonly affected, but your other toes, ankle, or knee may have symptoms, which include:
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<ul>
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<li>Intense pain</li>
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<li>Swelling</li>
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<li>Redness</li>
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<li>Feeling warm</li>
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</ul>
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</li>
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<li>Had or are having certain types of cancer treatments.</li>
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</ul>
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<p>You may also need a uric acid urine test if you:</p>
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<ul>
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<li>Have symptoms of a kidney stone, including:
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<ul>
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<li>Sharp <a data-tid="3061" href="https://medlineplus.gov/abdominalpain.html">pain in your lower abdomen</a> (belly), side, groin or back</li>
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<li>Blood in your urine</li>
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<li>Frequent urge to urinate (pee)</li>
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<li>Not being able to urinate at all or only urinating a little bit</li>
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<li>Pain when urinating</li>
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<li>Cloudy or bad-smelling urine</li>
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<li><a data-tid="489" href="https://medlineplus.gov/nauseaandvomiting.html">Nausea</a> and vomiting</li>
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<li><a data-tid="511" href="https://medlineplus.gov/fever.html">Fever</a> and chills</li>
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</ul>
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</li>
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<li>Have gout and your health care provider wants to monitor your risk for developing kidney stones</li>
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</ul></div>
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</section>
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<section><div class="mp-content"><h2>What happens during a uric acid test?</h2>
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<p>A uric acid test may be done as a blood test or a urine test. Your provider will decide which test you need.</p>
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<p><strong>For a blood test</strong>, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.</p>
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<p><strong>For a uric acid urine test</strong>, you'll need to collect all your urine during a 24-hour period. This is called a 24-hour urine sample test. You will be given a special container to collect your urine and instructions on how to collect and store your samples. Your provider will tell you what time to start. The test generally includes the following steps:</p>
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<ul>
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<li>To begin, urinate in the toilet as usual. Do not collect this urine. Write down the time you urinated.</li>
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<li>For the next 24 hours, collect all your urine in the container.</li>
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<li>During the collection period, store the urine container in a refrigerator or in a cooler with ice.</li>
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<li>24 hours after starting the test, try to urinate if you can. This is the last urine collection for the test.</li>
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<li>Return the container with your urine to your provider's office or the laboratory as instructed.</li>
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</ul></div>
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</section>
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<section><div class="mp-content"><h2>Will I need to do anything to prepare for the test?</h2>
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<p>Usually, you don't need any special preparations for a uric acid blood test. Many medicines, including aspirin, can affect your uric acid levels. Taking niacin (vitamin B-3) can also affect your results. So, be sure to tell your provider about all the medicines you take. But don't stop taking any medicines without talking with your provider first.</p></div>
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</section>
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<section><div class="mp-content"><h2>Are there any risks to the test?</h2>
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<p>There is no known risk to having a uric acid blood or urine test.</p></div>
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</section>
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<section><div class="mp-content"><h2>What do the results mean?</h2>
|
||
<p><strong>High uric acid levels in a blood test</strong> may happen if:</p>
|
||
<ul>
|
||
<li>Your body makes too much uric acid</li>
|
||
<li>Your kidneys can't remove uric acid from your blood</li>
|
||
<li>You are eating too many foods that cause high levels of purines such as:
|
||
<ul>
|
||
<li>Red meat and organ meats, including liver and kidney</li>
|
||
<li>Certain kinds of seafood, including shellfish, anchovies, sardines, trout, and tuna</li>
|
||
<li><a data-tid="1558" href="https://medlineplus.gov/alcohol.html">Alcohol</a> (all types)</li>
|
||
<li>High fructose corn syrup in soda and sweets</li>
|
||
</ul>
|
||
</li>
|
||
</ul>
|
||
<p>Your provider may order more tests to help diagnose what's causing the problem. High levels of uric acid may be related to many conditions, including:</p>
|
||
<ul>
|
||
<li>Gout</li>
|
||
<li><a data-tid="91" href="https://medlineplus.gov/kidneydiseases.html">Kidney disease</a></li>
|
||
<li><a data-tid="5620" href="https://medlineplus.gov/leukemia.html">Leukemia</a>, <a data-tid="332" href="https://medlineplus.gov/multiplemyeloma.html">multiple myeloma</a>, or cancer that has spread in your body (metastatic cancer)</li>
|
||
<li>Side effects from certain cancer treatments</li>
|
||
<li><a data-tid="120" href="https://medlineplus.gov/alcoholusedisorderaud.html">Alcohol use disorder</a></li>
|
||
<li><a data-tid="1508" href="https://medlineplus.gov/highbloodpressureinpregnancy.html">Preeclampsia</a>, a condition that can cause dangerously high blood pressure in pregnant women</li>
|
||
</ul>
|
||
<p><strong>Low levels of uric acid in blood</strong> are uncommon and usually don't cause health problems. Health conditions that are related to low uric acid levels are usually diagnosed using other tests.</p>
|
||
<p><strong>High uric levels in urine</strong>, may be related to:</p>
|
||
<ul>
|
||
<li>Gout</li>
|
||
<li>Kidney stones or having a high risk for kidney stones</li>
|
||
<li>Leukemia, multiple myeloma, or cancer that has spread in your body</li>
|
||
<li><a data-tid="61" href="https://medlineplus.gov/obesity.html">Obesity</a></li>
|
||
<li>An <a data-pid="20089" href="https://medlineplus.gov/genetics/understanding/inheritance/">inherited genetic condition</a>, such as <a data-pid="14549" href="https://medlineplus.gov/genetics/condition/lesch-nyhan-syndrome/">Lesch-Nyhan syndrome</a>, that makes it hard for your body to get rid of uric acid</li>
|
||
</ul>
|
||
<p><strong>Low levels of uric acid in urine</strong> may be related to kidney disease, <a data-tid="608" href="https://medlineplus.gov/leadpoisoning.html">lead poisoning</a>, or alcohol use disorder.</p>
|
||
<p>If your results show a high level of uric acid in your blood or urine, it doesn't always mean you have a condition that needs treatment. Many people have high levels of uric acid without having health problems.</p>
|
||
<p>If you have questions about your results, talk with your provider. Medicines and/or changes in your diet may help you keep your uric acid levels in a healthy range.</p>
|
||
<p>Learn more about <a data-pid="806" href="https://medlineplus.gov/lab-tests/how-to-understand-your-lab-results/">laboratory tests, reference ranges, and understanding results</a>.</p></div>
|
||
</section>
|
||
|
||
<section><div class="mp-content"></div>
|
||
</section>
|
||
|
||
<section><div class="mp-refs mp-content"><h2>References</h2>
|
||
<ol>
|
||
<li>Centers for Disease Control and Prevention [Internet]. Atlanta: U.S. Department of Health and Human Services; Gout; [reviewed 2020 Jul 27; cited 2022 Sep 25]; [about 4 screens]. Available from: <a href="https://www.cdc.gov/arthritis/gout/" target="bibliowin">https://www.cdc.gov/arthritis/gout/</a></li>
|
||
<li>George C, Minter DA. Hyperuricemia. [Updated 2022 Jul 18; cited 2022 Sep 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: <a href="https://www.ncbi.nlm.nih.gov/books/NBK459218/" target="bibliowin">https://www.ncbi.nlm.nih.gov/books/NBK459218/</a></li>
|
||
<li>Gupta A, Moore JA. Tumor Lysis Syndrome. JAMA Oncol. [Internet]. 2018 Jun [cited 2022 Sep 25]; 4(6):895.Available from: <a href="https://jamanetwork.com/journals/jamaoncology/fullarticle/2680750" target="bibliowin">https://jamanetwork.com/journals/jamaoncology/fullarticle/2680750</a></li>
|
||
<li>Hinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. 2nd Ed, Kindle. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Uric Acid, Serum and Urine; p. 506–7</li>
|
||
<li>Kids Health from Nemours [Internet]. Jacksonville (FL): The Nemours Foundation; c1995–2022. Blood Test: Uric Acid; [cited 2022 Sep 22]; [about 3 screens]. Available from: <a href="https://kidshealth.org/en/parents/test-uric.html" target="bibliowin">https://kidshealth.org/en/parents/test-uric.html</a></li>
|
||
<li>National Institute of Arthritis and Musculoskeletal and Skin Diseases [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Gout; [reviewed 2020 Feb; cited 2022 Sep 25]; [about 6 screens]. Available from: <a href="https://www.niams.nih.gov/health-topics/gout" target="bibliowin">https://www.niams.nih.gov/health-topics/gout</a></li>
|
||
<li>Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998–2022. High: uric acid level; [cited 2022 Sep 22]; [about 4 screens]. Available from: <a href="https://www.mayoclinic.org/symptoms/high-uric-acid-level/basics/definition/sym-20050607" target="bibliowin">https://www.mayoclinic.org/symptoms/high-uric-acid-level/basics/definition/sym-20050607</a></li>
|
||
<li>Merck Manual Consumer Version [Internet]. Kenilworth (NJ): Merck & Co. Inc.; c2022. Gout; [modified 2022 Sep; cited 2022 Sep 22]; [about 10 screens]. Available from: <a href="https://www.merckmanuals.com/home/bone-joint-and-muscle-disorders/gout-and-calcium-pyrophosphate-arthritis/gout" target="bibliowin">https://www.merckmanuals.com/home/bone-joint-and-muscle-disorders/gout-and-calcium-pyrophosphate-arthritis/gout</a></li>
|
||
<li>National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests; [cited 2022 Sep 22]; [about 7 screens]. Available from: <a href="https://www.nhlbi.nih.gov/health/blood-tests" target="bibliowin">https://www.nhlbi.nih.gov/health/blood-tests</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2022. Kidney Stone Testing; [modified 2021 Dec 3; cited 2022 Sep 22]; [about 10 screens]. Available from: <a href="https://www.testing.com/kidney-stone-testing/" target="bibliowin">https://www.testing.com/kidney-stone-testing/</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2022. Glossary: Preeclampsia; [cited 2022 Sep 22]; [about 1 screen]. Available from: <a href="https://www.testing.com/glossary/#toxemia-of-pregnancy-preeclampsia" target="bibliowin">https://www.testing.com/glossary/#toxemia-of-pregnancy-preeclampsia</a></li>
|
||
<li>Testing.com [Internet]. Seattle (WA): OneCare Media; c2022. Uric Acid; [modified 2021 Nov 9; cited 2022 Sep 22]; [about 8 screens]. Available from: <a href="https://www.testing.com/tests/uric-acid/" target="bibliowin">https://www.testing.com/tests/uric-acid/</a></li>
|
||
<li>UF Health: University of Florida Health [Internet]. Gainesville (FL): University of Florida; c2022. Uric Acid-blood: Overview; [updated 2019 Apr 29; cited 2022 Sep 22]; [about 3 screens]. Available from: <a href="https://ufhealth.org/uric-acid-blood" target="bibliowin">https://ufhealth.org/uric-acid-blood</a></li>
|
||
<li>UF Health: University of Florida Health [Internet]. Gainesville (FL): University of Florida; c2022. Uric Acid-urine Overview; [updated 2019 Apr 7; cited 2022 Sep 25]; [about 3 screens]. Available from: <a href="https://ufhealth.org/uric-acid-urine-test" target="bibliowin">https://ufhealth.org/uric-acid-urine-test</a></li>
|
||
<li>University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2022. Health Encyclopedia: 24-Hour Urine Collection; [cited 2022 Sep 22]; [about 6 screens]. Available from: <a href="https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=92&ContentID=P08955" target="bibliowin">https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=92&ContentID=P08955</a></li>
|
||
<li>University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2022. Health Encyclopedia: Uric Acid (Blood); [cited 2022 Sep 22]; [about 5 screens]. Available from: <a href="https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=uric_acid_blood" target="bibliowin">https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=uric_acid_blood</a></li>
|
||
<li>University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2022. Health Encyclopedia: Uric Acid (Urine); [cited 2022 Sep 22]; [about 5 screens]. Available from: <a href="https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=uric_acid_urine" target="bibliowin">https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=uric_acid_urine</a></li>
|
||
<li>UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2022. Health Information: Uric Acid in Blood Test; [updated 2022 Jun 27; cited 2022 Sep 22]; [about 3 screens]. Available from: <a href="https://patient.uwhealth.org/healthwise/article/en-us/aa12023" target="bibliowin">https://patient.uwhealth.org/healthwise/article/en-us/aa12023</a></li>
|
||
<li>UW Health [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; c2022. Health Information: Uric Acid in Urine Test; [updated 2022 Jun 27; cited 2022 Sep 22]; [about 3 screens]. Available from: <a href="https://patient.uwhealth.org/healthwise/article/en-us/aa15402" target="bibliowin">https://patient.uwhealth.org/healthwise/article/en-us/aa15402</a></li>
|
||
</ol></div>
|
||
</section>
|
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<h2>Related Health Topics</h2>
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|
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<ul class="relatedmp">
|
||
|
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<li><a href="https://medlineplus.gov/chronickidneydisease.html">Chronic Kidney Disease</a></li>
|
||
|
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|
||
<li><a href="https://medlineplus.gov/gout.html">Gout</a></li>
|
||
|
||
|
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<li><a href="https://medlineplus.gov/kidneydiseases.html">Kidney Diseases</a></li>
|
||
|
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<li><a href="https://medlineplus.gov/kidneyfailure.html">Kidney Failure</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/kidneystones.html">Kidney Stones</a></li>
|
||
|
||
|
||
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|
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|
||
</div></section>
|
||
|
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<section><div class="side-section">
|
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<div class="section-header">
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||
<h2>Related Medical Tests</h2>
|
||
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|
||
<div class="section-body">
|
||
<ul class="relatedmp">
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/calcium-blood-test/">Calcium Blood Test</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/calcium-in-urine-test/">Calcium in Urine Test</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/crystals-in-urine/">Crystals in Urine</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/how-to-cope-with-medical-test-anxiety/">How to Cope with Medical Test Anxiety</a></li>
|
||
|
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|
||
<li><a href="https://medlineplus.gov/lab-tests/how-to-understand-your-lab-results/">How to Understand Your Lab Results</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/kidney-stone-analysis/">Kidney Stone Analysis</a></li>
|
||
|
||
|
||
<li><a href="https://medlineplus.gov/lab-tests/synovial-fluid-analysis/">Synovial Fluid Analysis</a></li>
|
||
|
||
|
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|
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"description": "This test measures the amount of uric acid in a sample of your blood or urine (pee). Uric acid is a normal waste product that your body makes when it breaks down chemicals called purines. Purines come from your cells when they die. Purines are also found in many foods and beverages. Most uric acid dissolves in your blood. Your kidneys filter the uric acid out of your blood, and it leaves your body in your urine. If uric acid builds up in your blood, it can form needle-shaped crystals in and around your joints. This condition is called gout. Gout is a type of arthritis that causes painful swelling in your joints. High uric acid levels can also cause kidney stones, or kidney failure. But not everyone with high levels of uric acid will have these problems. Other names: serum urate, UA, uric acid: serum and urine",
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