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|
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Closing in on Nav1.7: A Promising Target for New Pain Treatments
|
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|
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</p>
|
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</div>
|
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<div class="visually-hidden field-label">Image</div>
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<img loading="lazy" src="/files/styles/callout_carousel/public/carpal-tunnel-image.jpeg?itok=tVL0L1It" width="900" height="507" alt="bandaged hand typing on keyboard showing carpal tunnel" class="img-fluid" />
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Pain Relief for Carpal Tunnel Syndrome
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<a href="/news/stories/technologies-neonatal-opioid-withdrawal" aria-label="Novel Technologies for Infants With Neonatal Opioid Withdrawal Syndrome">
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<div class="visually-hidden field-label">Image</div>
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<img loading="lazy" src="/files/styles/callout_carousel/public/spark-biomedical-device.png?itok=bG7F3Mca" width="900" height="507" alt="spark medical device with tablet screen showing drawing of each and 30% status" class="img-fluid" />
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<a href="/news/stories/technologies-neonatal-opioid-withdrawal">
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Novel Technologies for Infants With Neonatal Opioid Withdrawal Syndrome
|
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|
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</p>
|
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</div>
|
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<img loading="lazy" src="/files/styles/callout_carousel/public/opioids-dentistry-feature_0.jpg?itok=0ye3GveY" width="900" height="507" alt="dental tools, pills, and a glass of water" class="img-fluid" />
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<a href="/news/stories/sealing-the-deal">
|
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Sealing the Deal
|
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</a>
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<div class="carousel-item ">
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<a href="/news/stories/alternatives-to-morphine-after-surgery" aria-label="Designing Alternatives to Morphine After Surgery">
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<div>
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<div class="visually-hidden field-label">Image</div>
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<img loading="lazy" src="/files/styles/callout_carousel/public/morphine%20drip%20%282%29.png?itok=BEQynMA7" width="900" height="507" alt="Image of a morphine drip" class="img-fluid" />
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<a href="/news/stories/alternatives-to-morphine-after-surgery">
|
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Designing Alternatives to Morphine After Surgery
|
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</a>
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</p>
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</div>
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</div>
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</div>
|
||
</div>
|
||
|
||
</div>
|
||
<p class='col-12'>
|
||
<h2>Overview </h2>
|
||
|
||
<h3>The Research Need </h3>
|
||
|
||
<p>Addressing the current overdose crisis requires an all-hands-on-deck approach from all segments of the research community, including private enterprises. Funding from the Helping to End Addiction Long-term<sup>®</sup> Initiative, or NIH HEAL Initiative<sup>®</sup>, is available to eligible U.S. small businesses as part of the NIH Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs to provide science- and research-based solutions for the evolving opioid and pain public health challenges. </p>
|
||
|
||
<h3>About the Program </h3>
|
||
|
||
<p>The goal of NIH-funded SBIR/STTR programs is to encourage private-sector commercialization of technology and to increase small business participation in federally funded research and development activities. HEAL-funded SBIR/STTR projects focus specifically on developing innovative and commercializable technologies and products to prevent, diagnose, and treat opioid use disorder and overdose, as well as to enhance pain management. </p>
|
||
|
||
<p>Research includes development of small molecules, antibodies, gene therapy, therapeutic and diagnostic devices, assays, and other technologies. Also of interest are projects developing digital health products, pain models, research tools, health information technology, as well as education/training-focused products and services. </p>
|
||
|
||
</p>
|
||
</div>
|
||
</div>
|
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</div>
|
||
</div>
|
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|
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</div>
|
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<div class="paragraph paragraph--type--dynamic-content paragraph--view-mode--default">
|
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<div class='container'>
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<div class="dynamic_content">
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<div class="views-element-container form-group"><div class="viewsreference--view-title">
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</div>
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<div class="js-view-dom-id-212a41e7e66dfcaebf7bf98a481021dcea71139ca16cf4b21d266996c558c516">
|
||
|
||
|
||
|
||
<h2>Open Funding Opportunities</h2>
|
||
|
||
<div class="pattern">
|
||
|
||
|
||
|
||
|
||
|
||
|
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<div class="row border border-top-0 border-right-0 border-left-0 border-oslo-gray" style="padding: 15px 0;">
|
||
<div class="col-3 d-none d-lg-block">
|
||
2023
|
||
</div>
|
||
<div class="col-lg-6 col-md-12">
|
||
HEAL Commercialization Readiness Pilot (CRP) Program: Embedded Entrepreneurs for Small Businesses in Pain Management (SB1 Clinical Trial Not Allowed)
|
||
</div>
|
||
<div class="col-3 d-none d-lg-block">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=https://grants.nih.gov/grants/guide/pa-files/PAR-23-069.html>
|
||
NOFO Link
|
||
</a>
|
||
</div>
|
||
|
||
<div class="col-6 d-lg-none">
|
||
Jan 03, 2023
|
||
</div>
|
||
<div class="col-6 d-lg-none">
|
||
<a href="https://grants.nih.gov/grants/guide/pa-files/PAR-23-069.html">NOFO Link</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="row border border-top-0 border-right-0 border-left-0 border-oslo-gray" style="padding: 15px 0;">
|
||
<div class="col-3 d-none d-lg-block">
|
||
2022
|
||
</div>
|
||
<div class="col-lg-6 col-md-12">
|
||
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
|
||
</div>
|
||
<div class="col-3 d-none d-lg-block">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-007.html>
|
||
NOFO Link
|
||
</a>
|
||
</div>
|
||
|
||
<div class="col-6 d-lg-none">
|
||
Sep 15, 2022
|
||
</div>
|
||
<div class="col-6 d-lg-none">
|
||
<a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-007.html">NOFO Link</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="row border border-top-0 border-right-0 border-left-0 border-oslo-gray" style="padding: 15px 0;">
|
||
<div class="col-3 d-none d-lg-block">
|
||
2022
|
||
</div>
|
||
<div class="col-lg-6 col-md-12">
|
||
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
|
||
</div>
|
||
<div class="col-3 d-none d-lg-block">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-006.html>
|
||
NOFO Link
|
||
</a>
|
||
</div>
|
||
|
||
<div class="col-6 d-lg-none">
|
||
Sep 15, 2022
|
||
</div>
|
||
<div class="col-6 d-lg-none">
|
||
<a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-006.html">NOFO Link</a>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div style="text-align:right;">
|
||
|
||
|
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|
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|
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|
||
|
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|
||
|
||
|
||
|
||
<a class="btn btn-primary" href=/funding/open?research_program=42111>
|
||
View all
|
||
</a>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left pattern'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<h2 class='basic-content-grid-h2-no-media'>
|
||
Related Events
|
||
</h2>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<ul><li>11/8/2021: <a href="https://www.heal.nih.gov/events/non_addictive_analgesic_therapeutics_development_webinar">Small Businesses in Non-addictive Analgesic Therapeutics Development: HEAL Initiative Webinar on funding opportunities beyond SBIR/STTR</a></li></ul>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left pattern'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<h2 class='basic-content-grid-h2-no-media'>
|
||
Research Examples
|
||
</h2>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<p>Research examples supported by this program include: </p>
|
||
|
||
<ul>
|
||
<li>Developing instruments to measure the functional impact of chronic pain </li>
|
||
<li>Creating a noninvasive brain stimulation strategy to treat addiction </li>
|
||
<li>Developing a rapid screening, point-of-care test for neonatal infants </li>
|
||
<li>Designing and optimizing novel, peripherally restricted peptide agonists for receptors involved in pain signaling </li>
|
||
</ul>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--accordion paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class="pattern">
|
||
|
||
|
||
|
||
<div id="accordion-1952919059" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1952919059-0">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1952919059-0"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-1952919059-0">
|
||
Funded Institutions and Locations
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-1952919059-0"
|
||
class="collapse "
|
||
aria-labelledby="heading-1952919059-0"
|
||
data-parent="#accordion-1952919059">
|
||
<div class="card-body">
|
||
<ul>
|
||
<li><strong>Arrevus, Inc.</strong> – North Carolina </li>
|
||
<li><strong>Beacon Tech, Inc.</strong> – Maryland </li>
|
||
<li><strong>Emitech, Inc.</strong> – Massachusetts </li>
|
||
<li><strong>Hillmed, Inc.</strong> – Texas </li>
|
||
<li><strong>Mindlight, LLC</strong> – Massachusetts </li>
|
||
<li><strong>Olfax, LLC</strong> – North Carolina </li>
|
||
<li><strong>Opalgenix, Inc.</strong> – Indiana </li>
|
||
<li><strong>Opio Connect, Inc.</strong> – Montana </li>
|
||
<li><strong>Public Health Management Corporation</strong> – Pennsylvania </li>
|
||
<li><strong>Relate XR LLC</strong> – Indiana </li>
|
||
<li><strong>We the Village, Inc.</strong> – New York </li>
|
||
</ul>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-1016230019" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1016230019-1">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1016230019-1"
|
||
aria-expanded="false"
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2024
|
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</div>
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<div class="col-lg-6 col-md-12">
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Developing a novel epigenetic regulator as a treatment for opioid use disorder
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<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=/funding/awarded?research_program=42111#project-title-47671>
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Summary
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</a>
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</div>
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<div class="col-6 d-lg-none">
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<a href="/funding/awarded?research_program=42111#project-title-47671">Summary</a>
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<div class="col-6 d-lg-none">
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Nov 05, 2024
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|
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2024
|
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</div>
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<div class="col-lg-6 col-md-12">
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Development of a Novel Calcium Channel Therapeutic for Opioid Use Disorder
|
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<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=/funding/awarded?research_program=42111#project-title-47951>
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Summary
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</a>
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</div>
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<div class="col-6 d-lg-none">
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<a href="/funding/awarded?research_program=42111#project-title-47951">Summary</a>
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<div class="col-6 d-lg-none">
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Nov 05, 2024
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</div>
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2024
|
||
</div>
|
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<div class="col-lg-6 col-md-12">
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NX90: A Treatment for Overdose Caused by High Potency Opioids
|
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Summary
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</div>
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<div class="col-6 d-lg-none">
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<a href="/funding/awarded?research_program=42111#project-title-47731">Summary</a>
|
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</div>
|
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|
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<div class="col-6 d-lg-none">
|
||
Nov 05, 2024
|
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</div>
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</div>
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<div class="row border border-top-0 border-right-0 border-left-0 border-oslo-gray" style="padding: 15px 0;">
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<div class="col-3 d-none d-lg-block">
|
||
2024
|
||
</div>
|
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<div class="col-lg-6 col-md-12">
|
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Fast-track: Scalable digital delivery of evidence-based training for addiction professionals to maximize treatment admission and retention rates of opioid use disorder in affected families
|
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<div class="col-3 d-none d-lg-block">
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<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=/funding/awarded?research_program=42111#project-title-47896>
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Summary
|
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</a>
|
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</div>
|
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|
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<div class="col-6 d-lg-none">
|
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<a href="/funding/awarded?research_program=42111#project-title-47896">Summary</a>
|
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</div>
|
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|
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<div class="col-6 d-lg-none">
|
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Nov 05, 2024
|
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</div>
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</div>
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|
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2024
|
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</div>
|
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<div class="col-lg-6 col-md-12">
|
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Xylazine and opioid overdose mitigation therapy using decoy receptor biomimetic nanoparticles, NarcoBond platform
|
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</div>
|
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<div class="col-3 d-none d-lg-block">
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<a class="btn btn-tertiary my-2 my-sm-0 float-right" href=/funding/awarded?research_program=42111#project-title-47721>
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|
||
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|
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</div>
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<div class="col-6 d-lg-none">
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<a href="/funding/awarded?research_program=42111#project-title-47721">Summary</a>
|
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Nov 05, 2024
|
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