nih-gov/circulatingnow.nlm.nih.gov/wp-json/wp/v2/posts/2903

1 line
No EOL
28 KiB
Text

{"id":2903,"date":"2014-01-24T11:00:28","date_gmt":"2014-01-24T16:00:28","guid":{"rendered":"http:\/\/circulatingnow.nlm.nih.gov\/?p=2903"},"modified":"2024-12-12T11:36:35","modified_gmt":"2024-12-12T16:36:35","slug":"beer-yeast-and-louis-pasteur","status":"publish","type":"post","link":"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/","title":{"rendered":"Beer, Yeast, and Louis Pasteur"},"content":{"rendered":"<p>Circulating Now <em>welcomes guest bloggers <\/em><i>Diane Wendt and Mallory Warner from the Division of Medicine and Science at the <a title=\"Smithsonian National Museum of American History\" href=\"http:\/\/americanhistory.si.edu\/\" target=\"_blank\" rel=\"noopener\">Smithsonian National Museum of American History<\/a>. As curators of our most recent exhibition, <\/i><a title=\"NLM's Exhibition Program\" href=\"http:\/\/www.nlm.nih.gov\/exhibition\/fromdnatobeer\/index.html\">From DNA to Beer: Harnessing Nature in Medicine and Industry<\/a><i>, Diane and Mallory spent months researching four different microbes and the influence they\u2019ve had on human life. Beginning with this post they share some of the interesting things they found in their research<\/i><i>.<\/i><\/p>\n<p>Among the four microbes featured in <i>From DNA to Beer<\/i>, the little one cell creature named yeast may be our favorite.\u00a0 <a title=\"From DNA to Beer: Harnessing Nature in Medicine &amp; Industry\" href=\"http:\/\/www.nlm.nih.gov\/exhibition\/fromdnatobeer\/exhibition-brewing-mysteries.html\">In the exhibition<\/a>, we focus on the role yeast played in the work of Louis Pasteur, namely how his research on the \u201cdiseases\u201d of beer and other fermented products established yeast\u2019s connection to the process of alcoholic fermentation which, in turn, inspired his germ theory of disease. In focusing our view, however, we had to leave out the following exciting finds about beer, yeast, and Louis Pasteur.<\/p>\n<h3>Pasteur studied beer to get revenge on Germany<\/h3>\n<p>Pasteur\u2019s <a title=\"LocatorPlus Online Catalog\" href=\"https:\/\/catalog.nlm.nih.gov\/permalink\/01NLM_INST\/1o1phhn\/alma991494043406676\"><i>\u00c9tudes sur la bi\u00e8re <\/i><\/a>(translated as, <i>Studies on Fermentation: The Diseases of Beer, Their Causes, and the Means of Preventing Them)<\/i>, is celebrated for providing strong, elegant evidence dispelling spontaneous generation and for identifying the microbial causes of spoilage of beer.\u00a0 Having already studied \u201cdiseases\u201d in wine, vinegar, and silkworms, as noted in this <a title=\"From DNA to Beer: Harnessing Nature in Medicine &amp; Industry\" href=\"http:\/\/www.nlm.nih.gov\/exhibition\/fromdnatobeer\/digitalgallery\/detail-101237604.html\">catalog for an exhibit on Pasteur<\/a>, one might think beer was simply the next obvious problem product for Pasteur to fix.\u00a0 His introduction to <i>\u00c9tudes<\/i>, however, points to another reason for focusing on beer:<\/p>\n<div style=\"text-align: justify; padding-left: 75px; padding-right: 100px; padding-bottom: 25px; color: black;\"><i>Our misfortunes inspired me with the idea of these researches.\u00a0 I undertook them immediately after the war of 1870, and have since continued them without interruption, with the determination of perfecting them, and thereby benefiting a branch of industry wherein we are undoubtedly surpassed by Germany.<\/i><\/div>\n<p>Essentially, Pasteur funneled his anger over the French loss of the Franco-Prussian War into attacking that which Germany loves most:\u00a0 <a title=\"BBC News\" href=\"http:\/\/www.bbc.co.uk\/news\/business-25186518\" target=\"_blank\" rel=\"noopener\">beer<\/a>.\u00a0 He hoped increased knowledge about the science of beer brewing would put France in a position to best the German beer industry.<\/p>\n<h3>Yeast Advertising is\u2026 interesting<\/h3>\n<p>When considering whether to include some yeast-related objects in the exhibit, we delved into collections from several institutions.\u00a0 While none of these objects made it into the show, we couldn\u2019t help but share a few here:<\/p>\n<div class=\"tiled-gallery type-rectangular tiled-gallery-unresized\" data-original-width=\"840\" data-carousel-extra='{&quot;blog_id&quot;:1,&quot;permalink&quot;:&quot;https:\\\/\\\/circulatingnow.nlm.nih.gov\\\/2014\\\/01\\\/24\\\/beer-yeast-and-louis-pasteur\\\/&quot;,&quot;likes_blog_id&quot;:&quot;52242398&quot;}' itemscope itemtype=\"http:\/\/schema.org\/ImageGallery\" > <div class=\"gallery-row\" style=\"width: 840px; height: 353px;\" data-original-width=\"840\" data-original-height=\"353\" > <div class=\"gallery-group images-1\" style=\"width: 840px; height: 353px;\" data-original-width=\"840\" data-original-height=\"353\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/ahb2009q23749-jpg\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"836\"> <meta itemprop=\"height\" content=\"349\"> <img decoding=\"async\" class=\"\" data-attachment-id=\"2910\" data-orig-file=\"https:\/\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/magic-yeast-crate-label_blog.jpg\" data-orig-size=\"1024,427\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;National Museum of American History&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;Label.&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;This image was obtained from the Smithsonian Institution. The image or its contents may be protected by international copyright laws.&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;AHB2009q23749.jpg&quot;}\" data-image-title=\"AHB2009q23749.jpg\" data-image-description=\"\" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/magic-yeast-crate-label_blog.jpg?fit=300%2C125&#038;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/magic-yeast-crate-label_blog.jpg?fit=840%2C350&#038;ssl=1\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/magic-yeast-crate-label_blog.jpg?w=836&#038;h=349&#038;ssl=1\" width=\"836\" height=\"349\" loading=\"lazy\" data-original-width=\"836\" data-original-height=\"349\" itemprop=\"http:\/\/schema.org\/image\" title=\"AHB2009q23749.jpg\" alt=\"Wooden board reading Magic Yeast\" style=\"width: 836px; height: 349px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> Magic Yeast Crate. Courtesy National Museum of American History <\/div> <\/div> <\/div> <!-- close group --> <\/div> <!-- close row --> <div class=\"gallery-row\" style=\"width: 840px; height: 299px;\" data-original-width=\"840\" data-original-height=\"299\" > <div class=\"gallery-group images-1\" style=\"width: 432px; height: 299px;\" data-original-width=\"432\" data-original-height=\"299\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/fleischmanns-yeast-tin-sign_blog\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"428\"> <meta itemprop=\"height\" content=\"295\"> <img decoding=\"async\" class=\"\" data-attachment-id=\"2911\" data-orig-file=\"https:\/\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/fleischmanns-yeast-tin-sign_blog.jpg\" data-orig-size=\"1630,1123\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"Fleischmanns yeast tin sign_Blog\" data-image-description=\"\" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/fleischmanns-yeast-tin-sign_blog.jpg?fit=300%2C207&#038;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/fleischmanns-yeast-tin-sign_blog.jpg?fit=840%2C579&#038;ssl=1\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/fleischmanns-yeast-tin-sign_blog.jpg?w=428&#038;h=295&#038;ssl=1\" width=\"428\" height=\"295\" loading=\"lazy\" data-original-width=\"428\" data-original-height=\"295\" itemprop=\"http:\/\/schema.org\/image\" title=\"Fleischmanns yeast tin sign_Blog\" alt=\"Worn metal sign reading Fleischman &amp; Co&#039;s Vegetable Compressed Has No Equal.\" style=\"width: 428px; height: 295px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> Fleischman\u2019s Yeast Sign. Courtesy National Museum of American History. <\/div> <\/div> <\/div> <!-- close group --> <div class=\"gallery-group images-1\" style=\"width: 408px; height: 299px;\" data-original-width=\"408\" data-original-height=\"299\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/8190850181_370fcaa6f4_o_blog\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"404\"> <meta itemprop=\"height\" content=\"295\"> <img decoding=\"async\" class=\"\" data-attachment-id=\"2912\" data-orig-file=\"https:\/\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/8190850181_370fcaa6f4_o_blog.jpg\" data-orig-size=\"1500,1093\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"8190850181_370fcaa6f4_o_blog\" data-image-description=\"\" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/8190850181_370fcaa6f4_o_blog.jpg?fit=300%2C219&#038;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/8190850181_370fcaa6f4_o_blog.jpg?fit=840%2C612&#038;ssl=1\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/8190850181_370fcaa6f4_o_blog.jpg?w=404&#038;h=295&#038;ssl=1\" width=\"404\" height=\"295\" loading=\"lazy\" data-original-width=\"404\" data-original-height=\"295\" itemprop=\"http:\/\/schema.org\/image\" title=\"8190850181_370fcaa6f4_o_blog\" alt=\"An illustration showing children looing at the stars using a canister of Warner&#039;s Safe Yeast as a telescope.\" style=\"width: 404px; height: 295px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> Warner\u2019s Safe Yeast Postcard. Courtesy Boston Public Library: <a href=\"http:\/\/www.flickr.com\/photos\/boston_public_library\/8190850181\/\" rel=\"nofollow\">http:\/\/www.flickr.com\/photos\/boston_public_library\/8190850181\/<\/a> <\/div> <\/div> <\/div> <!-- close group --> <\/div> <!-- close row --> <\/div>\n<h3>Pasteur had his own newspaper.\u00a0 Sort of.<\/h3>\n<p>One of our favorite finds from the NLM collection was this advertising newspaper, <i><a title=\"LocatorPlus Online Catalog\" href=\"https:\/\/catalog.nlm.nih.gov\/permalink\/01NLM_INST\/1o1phhn\/alma997715213406676\">Le Pasteur<\/a><\/i>, first published by the Pasteur-Chamberland Filter Company of Dayton Ohio in 1889.\u00a0 When looking for a means to sterilize water in the lab without boiling, Pasteur found that passing the water through an unglazed porcelain filter removed bacterial contaminants.\u00a0 His student, Chamberland, designed a filter using this principle and the result became an important tool not only in the lab, but for filtering everyday drinking water.\u00a0 To advertise the sale of their filters, the Pasteur-Chamberland Company (the American licensee of the Pasteur-Chamberland filter patent) published <i>Le Pasteur<\/i>, a newspaper full of product testimonials, glorious documentation of Pasteur\u2019s achievements, and lists of the most recent establishments to purchase Pasteur-Chamberland filtration systems.\u00a0 Their over-dramatic sales tactics are endlessly entertaining.\u00a0 One delightful example of <i>Le Pasteur<\/i>\u2019s hyperbole can be found in the first stanza of a 44-line poem \u201cThe Old Oaken Bucket,\u201d published in the April 1889 edition.\u00a0 In it, the poet J. W. Bayles laments his childhood spent drinking well-water from a bucket, which he describes in disgusting detail.<\/p>\n<div style=\"text-align: justify; padding-left: 75px; padding-right: 25px; padding-bottom: 25px; color: black;\">\n<p><i>&#8220;With what anguish of mind I remember my childhood,<br \/>\nRecalled in the light of knowledge since gained;<br \/>\nThe malarious farm, the wet, fungus-grown wild-wood,<br \/>\nThe chills then contracted which since have remained;<br \/>\nThe scum-covered duck-pond, the pigsty close by it,<br \/>\nThe ditch where the sour-smelling house drainage fell.<br \/>\nThe damp, shaded dwelling, the foul barnyard nigh it\u2014<br \/>\nBut worse than all else was the terrible well.<br \/>\nAnd the old oaken bucket, the mold-crusted bucket,<br \/>\nThe moss-covered bucket that hung in the well.&#8221;<\/i><\/p>\n<\/div>\n<div class=\"tiled-gallery type-rectangular tiled-gallery-unresized\" data-original-width=\"840\" data-carousel-extra='{&quot;blog_id&quot;:1,&quot;permalink&quot;:&quot;https:\\\/\\\/circulatingnow.nlm.nih.gov\\\/2014\\\/01\\\/24\\\/beer-yeast-and-louis-pasteur\\\/&quot;,&quot;likes_blog_id&quot;:&quot;52242398&quot;}' itemscope itemtype=\"http:\/\/schema.org\/ImageGallery\" > <div class=\"gallery-row\" style=\"width: 840px; height: 613px;\" data-original-width=\"840\" data-original-height=\"613\" > <div class=\"gallery-group images-1\" style=\"width: 415px; height: 613px;\" data-original-width=\"415\" data-original-height=\"613\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/6971_large_web_blog\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"411\"> <meta itemprop=\"height\" content=\"609\"> <img decoding=\"async\" class=\"\" data-attachment-id=\"2916\" data-orig-file=\"https:\/\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_large_web_blog.jpg\" data-orig-size=\"1600,2370\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"6971_large_web_blog\" data-image-description=\"&lt;p&gt;The poem continues:&lt;br \/&gt; Just think of it! Moss on the vessel that lifted&lt;br \/&gt; The water I drank in the days called to mind&lt;br \/&gt; Ere I Knew what professors and scientists gifted&lt;br \/&gt; In the water of wells by analysis find.&lt;br \/&gt; The rotting wood fiber, the oxide of iron,&lt;br \/&gt; [unreadable]&lt;br \/&gt; The water impure as the versed of Byron,&lt;br \/&gt; Are things I remember with tears in my eyes.&lt;br \/&gt; To tell the sad truth, though I shudder to think it,&lt;br \/&gt; I considered that water uncommonly clear.&lt;br \/&gt; And often at noon when I went there to drink it,&lt;br \/&gt; I enjoyed it as much as I now enjoy beer.&lt;br \/&gt; How ardent I seized, with the hands that were grimy,&lt;br \/&gt; And quick to the mud covered bottom it fell;&lt;br \/&gt; Then reeking with nitrates and nitrites, and slimy&lt;br \/&gt; With matter organic, it rose from the well.&lt;\/p&gt; &lt;p&gt;Oh, had I but realized in time to avoid them,&lt;br \/&gt; The dangers that lurked in that pestilent draught,&lt;br \/&gt; I&#8217;d have tested for organic germs and destroyed them&lt;br \/&gt; With potassic permanganate ere I quaffed;&lt;br \/&gt; Or perchance I&#8217;d have boiled it and afterward strained it&lt;br \/&gt; Through filters of charcoal and gravel combined,&lt;br \/&gt; Or, after distilling, condensed and regained it&lt;br \/&gt; In portable form with the filth left behind.&lt;br \/&gt; How little I knew of the dread typhoid fever&lt;br \/&gt; Which lurked in the waters I ventured to drink;&lt;br \/&gt; But since I&#8217;ve become a devoted believer&lt;br \/&gt; In teachings of science, I shudder to think.&lt;br \/&gt; And now, far removed from the scene I&#8217;m describing,&lt;br \/&gt; The story for warning to others I tell,&lt;br \/&gt; As memory reverts to my youthful imbibing,&lt;br \/&gt; And I gag at the thought of that horrible well,&lt;br \/&gt; And the old oaken bucket, the fungus-grown bucket\u2014&lt;br \/&gt; In fact, the slop bucket that hung in the well.&lt;br \/&gt; \u2014J. W. Bayles&lt;\/p&gt; \" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_large_web_blog.jpg?fit=203%2C300&#038;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_large_web_blog.jpg?fit=691%2C1024&#038;ssl=1\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_large_web_blog.jpg?w=411&#038;h=609&#038;ssl=1\" width=\"411\" height=\"609\" loading=\"lazy\" data-original-width=\"411\" data-original-height=\"609\" itemprop=\"http:\/\/schema.org\/image\" title=\"6971_large_web_blog\" alt=\"First page of the Aril 1889 edition of Le Pasteur showing the mastead including an engraving of Pasteur and a stamp of the Army Medical Library\" style=\"width: 411px; height: 609px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> April 1889 edition of Le Pasteur. National Library of Medicine # 9429445 <a href=\"http:\/\/locatorplus.gov\/cgi-bin\/Pwebrecon.cgi?DB=local&#038;v2=1&#038;ti=1,1&#038;Search_Arg=9429445&#038;Search_Code=0359&#038;CNT=25&#038;SID=1\" rel=\"nofollow\">http:\/\/locatorplus.gov\/cgi-bin\/Pwebrecon.cgi?DB=local&#038;v2=1&#038;ti=1,1&#038;Search_Arg=9429445&#038;Search_Code=0359&#038;CNT=25&#038;SID=1<\/a> <\/div> <\/div> <\/div> <!-- close group --> <div class=\"gallery-group images-1\" style=\"width: 425px; height: 613px;\" data-original-width=\"425\" data-original-height=\"613\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/6971_bucket_illustration_crop_blog\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"421\"> <meta itemprop=\"height\" content=\"609\"> <img decoding=\"async\" class=\"\" data-attachment-id=\"2917\" data-orig-file=\"https:\/\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_bucket_illustration_crop_blog.jpg\" data-orig-size=\"830,1200\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"6971_bucket_illustration_Crop_blog\" data-image-description=\"\" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_bucket_illustration_crop_blog.jpg?fit=208%2C300&#038;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_bucket_illustration_crop_blog.jpg?fit=708%2C1024&#038;ssl=1\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/6971_bucket_illustration_crop_blog.jpg?w=421&#038;h=609&#038;ssl=1\" width=\"421\" height=\"609\" loading=\"lazy\" data-original-width=\"421\" data-original-height=\"609\" itemprop=\"http:\/\/schema.org\/image\" title=\"6971_bucket_illustration_Crop_blog\" alt=\"an engraving of a woman with a wooden bucket and a boy with a cup at a well.\" style=\"width: 421px; height: 609px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> &#8220;The Much Abused Old Oaken Bucket&#8221; from the April 1889 edition of Le Pasteur. National Library of Medicine # 9429445 <a href=\"http:\/\/locatorplus.gov\/cgi-bin\/Pwebrecon.cgi?DB=local&#038;v2=1&#038;ti=1,1&#038;Search_Arg=9429445&#038;Search_Code=0359&#038;CNT=25&#038;SID=1\" rel=\"nofollow\">http:\/\/locatorplus.gov\/cgi-bin\/Pwebrecon.cgi?DB=local&#038;v2=1&#038;ti=1,1&#038;Search_Arg=9429445&#038;Search_Code=0359&#038;CNT=25&#038;SID=1<\/a> <\/div> <\/div> <\/div> <!-- close group --> <\/div> <!-- close row --> <\/div>\n<h3>A Brewer\u2019s Portrait Pays Homage to Pasteur<\/h3>\n<p>Jacob Christian Jacobsen, head of the Carlsberg brewery in Copenhagen, was an admirer of the work of Louis Pasteur. In 1875 he established the Carlsberg Laboratory for the scientific study of the brewing process.\u00a0 This portrait, painted the year before he died, features a microscope, Pasteur flask, and Pasteur\u2019s book alongside a bottle of Carlsberg\u2019s famous beer.<\/p>\n<figure id=\"attachment_2919\" aria-describedby=\"caption-attachment-2919\" style=\"width: 650px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/jc_jacobsen_1886_by_august_jerndorff_blog.jpg\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"2919\" data-permalink=\"https:\/\/circulatingnow.nlm.nih.gov\/2014\/01\/24\/beer-yeast-and-louis-pasteur\/jc_jacobsen_1886_by_august_jerndorff_blog\/\" data-orig-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/jc_jacobsen_1886_by_august_jerndorff_blog.jpg?fit=796%2C1200&amp;ssl=1\" data-orig-size=\"796,1200\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"Portrait of Danish brewer J. C. Jacobsen painted by August Jerndorff, 1886\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Portrait of Danish brewer J. C. Jacobsen painted by August Jerndorff, 1886.&lt;br \/&gt;\nCourtesy &lt;\/p&gt;\n&lt;p&gt;Frederiksborg Museum&lt;\/p&gt;\n\" data-medium-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/jc_jacobsen_1886_by_august_jerndorff_blog.jpg?fit=199%2C300&amp;ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/jc_jacobsen_1886_by_august_jerndorff_blog.jpg?fit=679%2C1024&amp;ssl=1\" class=\"size-large wp-image-2919 \" title=\"Danish brewer J. C. Jacobsen\" src=\"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2013\/12\/jc_jacobsen_1886_by_august_jerndorff_blog.jpg?resize=650%2C979\" alt=\"A man stands holding a pen and journal at a table covered with books, a cmicroscope and chemical equipment including a pasteur flask.\" width=\"650\" height=\"979\" \/><\/a><figcaption id=\"caption-attachment-2919\" class=\"wp-caption-text\">Portrait of Danish brewer J. C. Jacobsen painted by August Jerndorff, 1886.<br \/><a title=\"Wikimedia Commons\" href=\"http:\/\/commons.wikimedia.org\/wiki\/File:JC_Jacobsen_1886_by_August_Jerndorff.jpg\" target=\"_blank\" rel=\"noopener\"><em>Courtesy Frederiksborg Museum<\/em><\/a><\/figcaption><\/figure>\n<p>In the 1880s, Emil Hansen, a scientist at the laboratory, isolated a pure strain of yeast that was suitable for lager brewing.\u00a0 He named the yeast S<i>accharomyces carlsbergensis<\/i> after the laboratory, and went on to isolate and identify numerous other strains of yeast including <i>Saccharomyces pastorianus<\/i>, named after Pasteur.\u00a0 And so the history of yeast science is embedded in the names given to this tiny organism responsible for much of the beer on the market.\u00a0 Today, the Carlsberg Laboratory remains an important center of yeast research.<\/p>\n<p><em>Explore<\/em> From DNA to Beer: Harnessing Nature in Medicine &amp; Industry <em>online for yourself at <a title=\"From DNA to Beer: Harnessing Nature in Medicine &amp; Industry\" href=\"http:\/\/www.nlm.nih.gov\/exhibition\/fromdnatobeer\/index.html\">http:\/\/www.nlm.nih.gov\/exhibition\/fromdnatobeer\/index.html<\/a>. To book the traveling exhibition or see when it comes to your town, visit the traveling exhibition page at <a title=\"NLM's Exhibition Program\" href=\"http:\/\/www.nlm.nih.gov\/hmd\/about\/exhibition\/fromdnatobeer-bookinfo.html\">http:\/\/www.nlm.nih.gov\/hmd\/about\/exhibition\/fromdnatobeer-bookinfo.html<\/a>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Circulating Now welcomes guest bloggers Diane Wendt and Mallory Warner from the Division of Medicine and Science at the Smithsonian<\/p>\n","protected":false},"author":19605840,"featured_media":3010,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[12763,2029,207572835,51014,2347],"tags":[521,1917,15888,470205,4704,3550,422],"class_list":["post-2903","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-collections","category-exhibitions","category-from-dna-to-beer","category-guests","category-series","tag-advertising","tag-beer","tag-collaboration","tag-fermentation","tag-france","tag-germany","tag-poetry"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/circulatingnow.nlm.nih.gov\/wp-content\/uploads\/2014\/01\/magic-yeast-crate-label_feature.jpg?fit=932%2C361&ssl=1","jetpack_likes_enabled":true,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p3xcDk-KP","jetpack-related-posts":[],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/posts\/2903","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/users\/19605840"}],"replies":[{"embeddable":true,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/comments?post=2903"}],"version-history":[{"count":43,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/posts\/2903\/revisions"}],"predecessor-version":[{"id":51304,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/posts\/2903\/revisions\/51304"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/media\/3010"}],"wp:attachment":[{"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/media?parent=2903"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/categories?post=2903"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/circulatingnow.nlm.nih.gov\/wp-json\/wp\/v2\/tags?post=2903"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}