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<li><p><a class="reference internal" href="#have-a-lot-of-blast-searches-to-run-run-it-with-elasticblast" id="id3">Have a lot of BLAST searches to run? Run it with ElasticBLAST!</a></p></li>
<li><p><a class="reference internal" href="#what-are-the-next-steps" id="id4">What are the next steps?</a></p></li>
<li><p><a class="reference internal" href="#resources" id="id5">Resources</a></p></li>
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<section id="have-a-lot-of-blast-searches-to-run-run-it-with-elasticblast">
<span id="cloudblast"></span><h1><a class="toc-backref" href="#id3" role="doc-backlink">Have a lot of BLAST searches to run? Run it with ElasticBLAST!</a><a class="headerlink" href="#have-a-lot-of-blast-searches-to-run-run-it-with-elasticblast" title="Link to this heading"></a></h1>
<p>Do you need to run high volume BLAST searches? Do you have proprietary sequence data to search and cannot use the
NCBI BLAST web site? Do you want to avoid the work to set-up and maintain stand-alone BLAST?
If you answered yes to any of these questions, read on!</p>
<p>NCBI provides <a class="reference external" href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/">ElasticBLAST</a> that can run your searches on the cloud.
BLAST workloads often come in bursts. You may want to search a large number of sequences all at once and need the results as soon as possible
to enable further analysis. Often the number of sequences and rapid turnaround needed preclude using a web service.
In many situations like this you also dont have a continuous need that would justify an investment in your own dedicated server.
Using ElasticBLAST to run your searches on the cloud is an ideal solution. Popular BLAST databases are also available in the cloud
allowing you to run computations close to the data, eliminating the time and resources needed to download large data files
to your local network. In the cloud, you are not restricted by local compute resources or limits on public web services
and dont have compute power that sits idle most of the time.</p>
</section>
<section id="what-are-the-next-steps">
<h1><a class="toc-backref" href="#id4" role="doc-backlink">What are the next steps?</a><a class="headerlink" href="#what-are-the-next-steps" title="Link to this heading"></a></h1>
<p>Getting started is easy! Being familiar with cloud services is helpful, but not necessary.
ElasticBLAST is supported on Amazon Web Services (AWS) and Google Cloud Platform (GCP).
It supports most BLAST programs and options and can easily run searches on discounted instances, meaning you can run
your searches for less.
We have instructions for using <a class="reference external" href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/">ElasticBLAST</a>,
which will guide you to the QuickStart for your cloud provider and let you try it out with minimal effort.</p>
</section>
<section id="resources">
<h1><a class="toc-backref" href="#id5" role="doc-backlink">Resources</a><a class="headerlink" href="#resources" title="Link to this heading"></a></h1>
<ul class="simple">
<li><p><a class="reference external" href="https://blast.ncbi.nlm.nih.gov/doc/elastic-blast/">ElasticBLAST</a> - How to get started with ElasticBLAST.</p></li>
<li><p><a class="reference external" href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05245-9">ElasticBLAST article</a> - The how and why of ElasticBLAST.</p></li>
<li><p><a class="reference external" href="https://github.com/ncbi/blast_plus_docs#blast-databases">Database information</a> How to obtain BLAST databases.</p></li>
<li><p><a class="reference external" href="https://github.com/ncbi/elastic-blast/">ElasticBLAST github page</a> - Source code for ElasticBLAST.</p></li>
<li><p><a class="reference external" href="https://github.com/ncbi/elastic-blast-demos/">ElasticBLAST demo scripts</a> - Demo scripts for ElasticBLAST.</p></li>
<li><p><a class="reference external" href="https://www.ncbi.nlm.nih.gov/books/NBK1763/">BLAST+ user manual</a> - How to run stand-alone BLAST searches.</p></li>
<li><p><a class="reference external" href="https://github.com/ncbi/blast_plus_docs">BLAST+ in a Docker image</a> - How to setup and run BLAST+ via Docker.</p></li>
</ul>
<p>We are always listening and welcome your feedback at <a class="reference external" href="https://support.nlm.nih.gov/knowledgebase/category/?id=CAT-01239">BLAST Support Center</a>.</p>
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