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<td colspan="5"><span class="issueDateMenu" >2011 SEPTEMBER–OCTOBER</span> <span class="issueNum">No. 382</span>
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<div class="actions">September 19, 2011 <span class="status">[posted]</span>
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<h1>New Clinical Advisory Issued by National Institute of Neurological Disorders and Stroke (NINDS)</h1>
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<p>
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The National Institute of Neurological Disorders and Stroke (NINDS) issued a new Clinical Advisory on September 19, 2011:
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</p>
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<dl>
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<dd><a href="//www.nlm.nih.gov/databases/alerts/2011_ninds_stroke.html">Secondary Prevention of Small Subcortical Strokes Trial: NINDS Stops Treatment with Combination Antiplatelet Therapy (Clopidogrel plus Aspirin) Due to Higher Risk of Major Hemorrhage and Death </a>
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</dd></dl>
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<p>
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NINDS has stopped the combination antiplatelet intervention in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial. This was a randomized, multicenter clinical trial conducted throughout North America, Latin America and Spain, to learn about preventing a second stroke in patients who had a subcortical stroke and to learn how to prevent cognitive problems after a stroke. </p>
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<p>
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Links to Clinical Alerts/Advisories can also be found from these NLM<span class="registered">®</span> Web sites:
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<ul>
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<li>A complete list of all Clinical Alerts/Advisories is available from the <a href="//www.nlm.nih.gov/databases/alerts/clinical_alerts.html">NIH Clinical Alerts and Advisories</a> page on the NLM Web site.</li>
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<li><a href="//www.nlm.nih.gov/medlineplus/">MedlinePlus</a>® features Clinical Alerts/Advisories as NIH Press Releases on the appropriate Health Topics page(s).</li>
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<li><a href="//www.ncbi.nlm.nih.gov/sites/entrez">PubMed</a>®, the <a href="//gateway.nlm.nih.gov/gw/Cmd">NLM Gateway</a> and <a href="//clinicaltrials.gov/">ClinicalTrials.gov</a> each have access points to the Clinical Alerts/Advisories.
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<p class="citation">New Clinical Advisory Issued by National Institute of Neurological Disorders and Stroke (NINDS). NLM Tech Bull. 2011 Sep-Oct;(382):e6. </p>
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