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<a class='nav-link nav-link-header' href='http://www.clinicalgenome.org/docs/guidelines-for-applying-for-variant-or-gene-curation-expert-panel-status'><span class=' d-inline-block text-truncate'> Learn how to start an Expert Panel </span></a>
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<input type="hidden" class="buildtype" name="type" value="">
<span class="input-group-addon" id=""><i class="fas fa-search"></i></span>
<div class="input-group-btn">
<button type="button" class="btn btn-default dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"><span class='typeQueryLabel'>Gene Symbol </span></button>
<ul class="dropdown-menu dropdown-menu-left">
<li><a class="typeQueryGene pointer">Gene Symbol</a></li>
<!-- <li><a class="typeQueryGeneName pointer">Gene Name</a></li> -->
<li><a class="typeQueryDisease pointer">Disease Name</a></li>
<li><a class="typeQueryDrug pointer">Drug Name</a></li>
<li><a class="typeQueryRegionGRCh37 pointer">Region (GRCh37)</a></li>
<li><a class="typeQueryRegionGRCh38 pointer">Region (GRCh38)</a></li>
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</ul>
</div><!-- /btn-group -->
<span class="inputQueryGene">
<input type="text" class="form-control queryGene" aria-label="..." value="" name="search[]" placeholder="Enter a gene symbol or HGNC ID (Examples: ADNP, HGNC:15766)">
</span>
<!--<span class="inputQueryGeneName" style="display: none">
<input type="text" class="form-control queryGeneName" aria-label="..." value="" name="search[]" placeholder="Enter a gene name (Example: Adenylate cyclase 1)" >
</span>-->
<span class="inputQueryDisease" style="display: none">
<input type="text" class="form-control queryDisease" aria-label="..." value="" name="search[]" placeholder="Enter a disease name or MONDO ID (Examples: Loeys Dietz, MONDO:0018954)" >
</span>
<span class="inputQueryDrug" style="display: none">
<input type="text" class="form-control queryDrug" aria-label="..." value="" name="search[]" placeholder="Enter a drug name or RXNORM ID (Examples: aspirin, RXNORM:1191)">
</span>
<span class="inputQueryRegion" style="display: none">
<input type="text" class="form-control queryRegion" aria-label="..." value="" name="search[]" placeholder="Enter a full or partial region, or full cytoband (Examples: chr7:75158048-76063176, chr7, chr7:70008000, 12q24.31)">
</span>
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<button class="btn btn-default btn-search-submit" type="submit">Search</button>
</span>
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<li class="nav-item dropdown ">
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</a>
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<li><a class="" href="https://search.clinicalgenome.org/kb/genes/curations">All Curated Genes</a></li>
<!--<li><a class=""" href="https://search.clinicalgenome.org/kb/genes/acmgsf">ACMG SF v3.2 Curations</a></li>-->
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<li class="nav-item dropdown ">
<a class="nav-link dropdown-toggle" href="https://search.clinicalgenome.org/kb/gene-validity" aria-haspopup="true" aria-expanded="false">
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<li><a class="" href="https://search.clinicalgenome.org/kb/gene-validity">All Curations</a></li>
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<li class="nav-item dropdown active ">
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Dosage Sensitivity
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<ul class="dropdown-menu">
<li><a class="" href="https://search.clinicalgenome.org/kb/gene-dosage">All Curations</a></li>
<li><a class="" href="https://search.clinicalgenome.org/kb/gene-dosage/cnv">Recurrent CNV</a></li>
<li class="divider"></li>
<li><a href="https://search.clinicalgenome.org/kb/downloads/#section_dosage"><i class="fas fa-download"></i> FTP File Downloads (CSV, BED, TSV)</a></li>
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<a class="nav-link dropdown-toggle" target="external-erepo" href="https://search.clinicalgenome.org/kb/variant-pathogenicity/all" aria-haspopup="true" aria-expanded="false">
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<div class="col-md-5">
<table class="mt-3 mb-2">
<tr>
<td class="valign-top"><img src="/images/dosageSensitivity-on.png" width="40" height="40"></td>
<td class="pl-2">
<h1 class="h2 p-0 m-0"> Dosage Sensitivity</h1>
</td>
</tr>
</table>
</div>
<div class="col-md-4 mt-3">
<!--<div class='mt-2 table-selector' style='float:left;'>
<span class="action-show-genes-btn pointer"><span class="dosage-box gene mr-1">G</span><span >Show Genes <i class="fas fa-toggle-on fa-lg action-show-genes"></i></span></span>
<span class="action-show-regions-btn pointer"><span class="dosage-box region ml-4 mr-1">R</span><span >Show Regions <i class="fas fa-toggle-on fa-lg action-show-regions"></i></span></span>
</div>-->
<div class="btn-group float-left mt-1" role="group" aria-label="...">
<button class="btn btn-success action-show-genes"><b>Genes: On</b></button>
<button class="btn btn-success action-show-regions"><b>Regions: On</b></button>
</div>
</div>
<div class="col-md-3">
<div class="">
<div class="text-right p-2">
<ul class="list-inline pb-0 mb-0 small">
<li class="text-stats line-tight text-center pl-3 pr-3"><span
class="countCurations text-18px"><i
class="glyphicon glyphicon-refresh text-18px text-muted"></i></span><br />Total<br />Curations
</li>
<li class="text-stats line-tight text-center pl-3 pr-3"><span class="countGenes text-18px"><i
class="glyphicon glyphicon-refresh text-18px text-muted"></i></span><br />Total<br />Genes
</li>
<li class="text-stats line-tight text-center pl-3 pr-3"><span class="countRegions text-18px"><i
class="glyphicon glyphicon-refresh text-18px text-muted"></i></span><br />Total<br />Regions
</li>
</ul>
</div>
</div>
</div>
<div class="col-md-12">
<div class="alert alert-warning redblur" role="alert">
<p>
<span class="text-danger"><b>NOTICE:</b></span>
The standalone region search field specific to Dosage Sensitivity has been fully integrated with the <u>main search bar above</u> <i class="fas fa-arrow-up"></i>.
To use, first select Region (GRCh37) or Region (GRCh38) from the pull-down menu, enter the genomic coordinates as before, then click on the 'Search' button.
Once your results display, you can view additional information relative to Dosage Sensitivity by clicking on the 'Dosage Scores' display option.
For more information, refer to the <a href="https://www.clinicalgenome.org/site/assets/files/9582/r1_10_release_notes.pdf" target="_notes"><u>release notes.</u></a>
</p>
<p>
Note that the search box below <i class="fas fa-arrow-down"></i> only searches for text within the displayed table; do not use this to search for all genes within a range of genomic coordinates.
</p>
</div>
</div>
<div class="col-md-12">
<button type="button" class="btn-link p-0 m-0" data-toggle="modal" data-target="#modalFilter">
<span class="text-muted font-weight-bold mr-1"><small><i class="glyphicon glyphicon-tasks" style="top: 2px"></i> Advanced Filters: </small></span><span class="filter-container"><span class="badge action-af-badge">None</span></span>
</button>
<span class="text-info font-weight-bold mr-1 float-right action-hidden-columns hidden"><small>Click on <i class="glyphicon glyphicon-th icon-th" style="top: 2px"></i> below to view hidden columns</small></span>
</div>
<div class="col-md-12 light-arrows dark-table dark-detail">
<!-- The toolbar -->
<div id="toolbar">
</div>
<!-- The table -->
<table
id="table"
data-classes="table"
data-toolbar="#toolbar"
data-addrbar="true"
data-search="true"
data-filter-control="true"
data-filter-control-visible="false"
data-id-table="advancedTable"
data-search-align="left"
data-trim-on-search="true"
data-show-search-clear-button="true"
data-buttons="table_buttons"
data-show-align="left"
data-show-fullscreen="true"
data-show-columns="true"
data-show-columns-toggle-all="true"
data-search-formatter="false"
data-show-export="true"
data-export-types="['json', 'xml', 'csv', 'txt', 'sql', 'xlsx', 'pdf']"
data-detail-view="true"
data-detail-view-by-click="true"
data-detail-view-icon="true"
data-minimum-count-columns="2"
data-pagination="true"
data-id-field="id"
data-ajax-options="ajaxOptions"
data-page-list="[10, 25, 50, 100, 250, all]"
data-page-size="25"
data-show-footer="true"
data-side-pagination="client"
data-pagination-v-align="both"
data-show-extended-pagination="false"
data-url="/api/dosage"
data-query-params="queryParams"
data-response-handler="responseHandler"
data-header-style="headerStyle"
data-show-filter-control-switch="true"
data-group-by="true"
data-group-by-field="pheno">
</table>
</div>
</div>
</div>
<div class="modal" id="modalFilter" tabindex="-1" role="dialog" aria-labelledby="modalFilterTitle" aria-hidden="true">
<div class="modal-dialog modal-lg modal-dialog-centered" role="document">
<div class="modal-content">
<div class="modal-header">
<h5 class="modal-title" id="modalFilterTitle">Advanced Filters</h5>
</div>
<div class="modal-body">
<p>Select the appropriate view filters to modify the displayed rows: </p>
<input type="hidden" name="_token" value="cQDtFK9v0wYGJfPmhVUB2MJPSYBLyIZD8SdCFTrx"> <input type="hidden" name="ident" value="">
<div class="form-group row bg-light border-1 border-muted ml-2 mr-2 p-2">
<!--<label for="gene" class="col-sm-6 ml-5 col-form-label">Show Genes</label>
<div class="col-sm-4">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-on fa-lg action-show-genes"></i>
<span class="ml-4 hgnc text-muted action-show-genes-text">On</span>
</div>
</div>
<label for="gene" class="col-sm-6 ml-5 col-form-label">Show Regions</label>
<div class="col-sm-4">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-on fa-lg action-show-regions"></i>
<span class="ml-4 hgnc text-muted action-show-regions-text">On</span>
</div>
</div>-->
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Genes/Regions with HI Score 3 (Sufficient Evidence) </label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-hiknown" data-badge="Known HI"></i>
<span class="ml-2 hgnc text-muted action-show-hiknown-text">Off</span>
</div>
</div>
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Genes/Regions with TS Score 3 (Sufficient Evidence) </label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-tsknown" data-badge="Known TS"></i>
<span class="ml-2 hgnc text-muted action-show-tsknown-text">Off</span>
</div>
</div>
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Genes/Regions with TS Score 3 <u>or</u> HI Score 3 </label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-hitsknown" data-badge="Known HI or TS"></i>
<span class="ml-2 hgnc text-muted action-show-hitsknown-text">Off</span>
</div>
</div>
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Genes/Regions with scores changed in the past year </label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-new" data-badge="Score Change 365"></i>
<span class="ml-2 hgnc text-muted action-show-new-text">Off</span>
</div>
</div>
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Genes/Regions reviewed in the past 90 days</label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-recent" data-badge="Show Recent"></i>
<span class="ml-2 hgnc text-muted action-show-recent-text">Off</span>
</div>
</div>
<label for="gene" class="col-sm-8 ml-5 col-form-label">Show only Protein-Coding Genes</label>
<div class="col-sm-3">
<div class="form-inline p-0 m-0 col-sm-12">
<i class="fas fa-toggle-off fa-lg advanced-filter action-show-protein" data-badge="Protein Coding"></i>
<span class="ml-2 hgnc text-muted action-show-protein-text">Off</span>
</div>
</div>
</div>
</div>
<div class="modal-footer">
<!--<button type="submit" class="btn btn-primary mr-auto">Submit
</button> -->
<button type="button" class="btn btn-outline-secondary" data-dismiss="modal" aria-label="Close">
Close
</button>
</div>
</div>
</div>
</div>
<div class="modal" id="modalBookmark" tabindex="-1" role="dialog" aria-labelledby="modalBookmarkTitle" aria-hidden="true">
<div class="modal-dialog modal-dialog-centered" role="document">
<div class="modal-content">
<div class="modal-header section-heading-groups">
<button type="button" class="close text-white" data-dismiss="modal" aria-label="Close">
<span aria-hidden="true">&times;</span>
</button>
<h3 class="modal-title text-white" id="modalBookmarkTitle">Manage Page Preferences</h3>
</div>
<div class="alert alert-warning mb-0" role="alert">
<b>Page Preferences</b> allow you to save and restore individual settings to your preference.
Currently this <b>new feature</b> allows you to manage table page number, table page size, table search string,
and table column sort order. Future releases will also manage advanced filters, column layout, and column search settings.
</div>
<div class="modal-body">
<div class="row">
<div class="col-md-12">
<form class="form-horizontal" role="form">
<input type="hidden" name="_token" value="cQDtFK9v0wYGJfPmhVUB2MJPSYBLyIZD8SdCFTrx"> <fieldset>
<!-- Text input-->
<div class="form-group">
<h5 class="col-sm-11"><b>Dosage Sensitivity Page</b></h5>
</div>
<!-- Text input-->
<div class="form-group">
<label class="col-sm-6 control-label" for="textinput">Current Selected Preference:</label>
<div class="col-sm-5 pt-2">
<span id="modal-current-bookmark">No Preferences Selected</span>
</div>
</div>
<hr />
<p>Manage all your preferences for this page my selecting from the "Choose Preference" list, select an action, then click on "Go!".
</p>
<div class="row">
<div class="col-sm-12">
<div class="input-group">
<div class="input-group-btn">
<button type="button" class="btn btn-default dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Choose Preference </button>
<ul id="preferences-menu" class="dropdown-menu dropdown-menu-right">
</ul>
</div><!-- /btn-group -->
<input id="bookmark-selected-preference" type="text" class="form-control" aria-label="" value="" readonly>
<div class="input-group-btn">
<button type="button" class="rounded-0 btn btn-default dropdown-toggle bookmark-action-select" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"><span id="button-selected-action">Action </span> </button>
<ul class="dropdown-menu dropdown-menu-right">
<li><a href="#" class="bookmark-modal-select action-restore-bookmark" data-action="select"><i class="fas fa-check"></i> Select </a></li>
<li><a href="#" class="bookmark-modal-select action-default-bookmark" data-action="default"><i class="fas fa-asterisk"></i> Make Default </a></li>
<li><a href="#" class="bookmark-modal-select action-update-bookmark" data-action="update"><i class="far fa-edit"></i> Update </a></li>
<li role="separator" class="divider"></li>
<li><a href="#" class="bookmark-modal-select action-remove-bookmark" data-action="remove"><i class="far fa-trash-alt"></i> Delete </a></li>
</ul>
</div><!-- /btn-group -->
<div class="input-group-btn">
<button type="button" class="btn btn-primary bookmark-action-go">Go!</button>
</div>
</div><!-- /input-group -->
</div><!-- /.col-sm-10 -->
</div><!-- /.row -->
<hr />
<p>To create a new preference comprised of the current settings, first enter a unique name, then click on "Go!".</p>
<div class="input-group">
<span class="input-group-addon" id="sizing-addon2">Preference Name:</span>
<input type="text" class="form-control" id="modal-new-bookmark" name="newbookmark" placeholder="Enter a name" aria-describedby="sizing-addon2">
<span class="input-group-btn">
<button class="btn btn-primary action-save-bookmark" type="button">Go!</button>
</span>
</div>
</fieldset>
</form>
</div><!-- /.col-lg-12 -->
</div><!-- /.row -->
</div>
<div class="modal-footer">
<div id="modal-bookmark-status" class="text-danger pull-left">&nbsp;</div>
</div>
</div>
</div>
</div>
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<div class="modal-dialog modal-dialog-centered modal-lg" role="document">
<div class="modal-content">
<div class="modal-body p-0">
<div class="card login-card">
<div class="row no-gutters">
<div class="col-md-4 hidden-sm hidden-xs">
<img src="/assets/images/dna_spiral.jpg" alt="login" style="width:100%; height: 520px; object-fit: cover;">
</div>
<div class="col-md-8">
<button type="button" class="close mr-4 mt-4" data-dismiss="modal" aria-label="Close">
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<a class='' href='https://www.clinicalgenome.org/start/'><h6>Get Started</h6></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/curation-activities/gene-disease-validity/'><span class='d-inline-block text-truncate'>Gene-Disease Validity</span></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/gene-curation/'><span class='d-inline-block text-truncate'>Gene Curation</span></a>
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<!-- <li class='col-md-6 text-truncate'>
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<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/low-penetrance-risk-allele-working-group/'><span class='d-inline-block text-truncate'>Low Penetrance/Risk Allele Working Group</span></a>
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<!-- <li class='col-md-6 text-truncate'>
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<li class='col-md-6 text-truncate '>
<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/pharmacogenomics/'><span class=' d-inline-block text-truncate'> Pharmacogenomics Intrepretation Committee</span></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/pseudodeficiency-working-group/'><span class=' d-inline-block text-truncate'> Pseudodeficiency Working Group</span></a>
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<!-- <li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/sequence-variant-inter-laboratory-discrepancy-resolution/'><span class='d-inline-block text-truncate'>Sequence Variant Inter-Laboratory Discrepancy Resolution</span></a>
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<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/sequence-variant-interpretation/'><span class='d-inline-block text-truncate'>Sequence Variant Interpretation</span></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/somatic-germline-variant-curation/'><span class='d-inline-block text-truncate'>Germline/Somatic Working Group</span></a>
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<!-- <li class='col-md-6 text-truncate'>
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<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/steering-committee/'><span class='d-inline-block text-truncate'>Steering Committee</span></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/working-groups/variant-curation-workgroup/'><span class='d-inline-block text-truncate'>Variant Curation</span></a>
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<a class="" href="https://clinicalgenome.org/affiliation/"><h6>Expert Panels</h6></a>
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<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50048/"><span class=" d-inline-block ">ACADVL Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40011/"><span class=" d-inline-block ">Aminoacidopathy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40003/"><span class=" d-inline-block ">Arrhythmogenic Right Ventricular Cardiomyopathy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40020/"><span class=" d-inline-block ">Brain Malformations Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50020/"><span class=" d-inline-block ">Brain Malformations Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40042/"><span class=" d-inline-block ">Breast/Ovarian Cancer Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40045/"><span class=" d-inline-block ">Brugada Syndrome Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50002/"><span class=" d-inline-block ">Cardiomyopathy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50014/"><span class=" d-inline-block ">CDH1 Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50047/"><span class=" d-inline-block ">Cerebral Creatine Deficiency Syndromes Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40063/"><span class=" d-inline-block ">Charcot-Marie-Tooth Disease Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50041/"><span class=" d-inline-block ">Coagulation Factor Deficiency Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40043/"><span class=" d-inline-block ">Colon Cancer Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40031/"><span class=" d-inline-block ">Congenital Myopathies Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50031/"><span class=" d-inline-block ">Congenital Myopathies Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40059/"><span class=" d-inline-block ">Craniofacial Malformations Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50050/"><span class=" d-inline-block ">DICER1 and miRNA-Processing Gene Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40035/"><span class=" d-inline-block ">Dilated Cardiomyopathy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40005/"><span class=" d-inline-block ">Epilepsy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50004/"><span class=" d-inline-block ">Familial Hypercholesterolemia Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40044/"><span class=" d-inline-block ">Familial Thoracic Aortic Aneurysm and Dissection Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40010/"><span class=" d-inline-block ">Fatty Acid Oxidation Disorders Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50046/"><span class=" d-inline-block ">FBN1 Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40026/"><span class=" d-inline-block ">General Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50053/"><span class=" d-inline-block ">Glaucoma Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50078/"><span class=" d-inline-block ">GRIN Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40007/"><span class=" d-inline-block ">Hearing Loss Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50007/"><span class=" d-inline-block ">Hearing Loss Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50052/"><span class=" d-inline-block ">Hemoglobinopathy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40028/"><span class=" d-inline-block ">Hemostasis/Thrombosis Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50039/"><span class=" d-inline-block ">Hereditary Breast, Ovarian and Pancreatic Cancer Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40023/"><span class=" d-inline-block ">Hereditary Cancer Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50037/"><span class=" d-inline-block ">Hereditary Hemorrhagic Telangiectasia Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40080/"><span class=" d-inline-block ">Humoral Defects Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40008/"><span class=" d-inline-block ">Hypertrophic Cardiomyopathy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40006/"><span class=" d-inline-block ">Intellectual Disability and Autism Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50001/"><span class=" d-inline-block ">KCNQ1 Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40066/"><span class=" d-inline-block ">Kidney Cystic and Ciliopathy Disorders Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50066/"><span class=" d-inline-block ">Kidney Cystic and Ciliopathy Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50082/"><span class=" d-inline-block ">Leber Congenital Amaurosis/early onset Retinal Dystrophy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40061/"><span class=" d-inline-block ">Limb Girdle Muscular Dystrophy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50061/"><span class=" d-inline-block ">Limb Girdle Muscular Dystrophy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40025/"><span class=" d-inline-block ">Long QT Syndrome Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50009/"><span class=" d-inline-block ">Lysosomal Storage Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50038/"><span class=" d-inline-block ">Malignant Hyperthermia Susceptibility Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50027/"><span class=" d-inline-block ">Mitochondrial Disease Nuclear and Mitochondrial Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40027/"><span class=" d-inline-block ">Mitochondrial Diseases Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40016/"><span class=" d-inline-block ">Monogenic Diabetes Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50016/"><span class=" d-inline-block ">Monogenic Diabetes Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50034/"><span class=" d-inline-block ">Myeloid Malignancy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50089/"><span class=" d-inline-block ">NTRK Fusions Somatic Cancer Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40079/"><span class=" d-inline-block ">Parkinson's Disease Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40049/"><span class=" d-inline-block ">Peroxisomal Disorders Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50049/"><span class=" d-inline-block ">Peroxisomal Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50015/"><span class=" d-inline-block ">Phenylketonuria Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50040/"><span class=" d-inline-block ">Platelet Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50012/"><span class=" d-inline-block ">PTEN Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40071/"><span class=" d-inline-block ">Pulmonary Hypertension Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40021/"><span class=" d-inline-block ">RASopathy Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50021/"><span class=" d-inline-block ">RASopathy Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40072/"><span class=" d-inline-block ">Retina Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50022/"><span class=" d-inline-block ">Rett and Angelman-like Disorders Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40081/"><span class=" d-inline-block ">SCID-CID Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40065/"><span class=" d-inline-block ">Skeletal Disorders Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/40060/"><span class=" d-inline-block ">Syndromic Disorders Gene Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50064/"><span class=" d-inline-block ">Thrombosis Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50013/"><span class=" d-inline-block ">TP53 Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50036/"><span class=" d-inline-block ">VHL Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50051/"><span class=" d-inline-block ">von Willebrand Disease Variant Curation Expert Panel</span></a>
</li>
<li class="col-md-6 text-truncate">
<a class="text-dark small" href="https://clinicalgenome.org/affiliation/50086/"><span class=" d-inline-block ">X-linked Inherited Retinal Disease Variant Curation Expert Panel</span></a>
</li>
</ul>
<hr>
</div>
<div class="col-12">
<a class='' href='https://www.clinicalgenome.org/docs/'><h6>Documents &amp; Announcements</h6></a>
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<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=announcement#list_documentation_table'><span class=' d-inline-block text-truncate'>Announcements</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=clingen-exhibit-booth-materials#list_documentation_table'><span class=' d-inline-block text-truncate'>ClinGen Exhibit Booth Materials</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=curation-activity-procedures#list_documentation_table'><span class=' d-inline-block text-truncate'>Curation Activity Procedures</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=conflict-of-interest-coi#list_documentation_table'><span class=' d-inline-block text-truncate'>Conflict Of Interest (COI)</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=data-sharing-resources#list_documentation_table'><span class=' d-inline-block text-truncate'>Data Sharing Resources</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=expert-panel-status-steps#list_documentation_table'><span class=' d-inline-block text-truncate'>Expert Panel Applications</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=in-the-news#list_documentation_table'><span class=' d-inline-block text-truncate'>News</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=moc-cme-forms#list_documentation_table'><span class=' d-inline-block text-truncate'>MOC/CME Forms</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=patient-data-sharing#list_documentation_table'><span class=' d-inline-block text-truncate'>Patient Data Sharing</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=policies-position-statements#list_documentation_table'><span class=' d-inline-block text-truncate'>Policies/Position Statements</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=presentations#list_documentation_table'><span class=' d-inline-block text-truncate'>Presentations</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=publications#list_documentation_table'><span class=' d-inline-block text-truncate'>Publication</span></a>
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<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=supporting-documents#list_documentation_table'><span class=' d-inline-block text-truncate'>Supporting Documents</span></a>
</li>
<li class='col-md-6 text-truncate'>
<a class='text-dark small' href='https://www.clinicalgenome.org/docs/?doc-type=training-materials#list_documentation_table'><span class=' d-inline-block text-truncate'>Training Materials</span></a>
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</ul>
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filterControl: 'input',
searchFormatter: false,
sortable: true,
visible: false
},
{
title: 'Triplo Disease ID',
field: 'triplo_disease_id',
//formatter: haploFormatter,
cellStyle: cellFormatter,
filterControl: 'input',
searchFormatter: false,
sortable: true,
visible: false
},
{
title: 'OMIM<hr class="mt-1 mb-1 bg-white mr-4">Morbid',
field: 'omimcombo',
formatter: omimcomboFormatter,
cellStyle: cellFormatter,
filterControl: 'select',
filterData: 'var:omimcomboChoices',
searchFormatter: false,
sortable: true
},
/*{
title: '<div><i class="fas fa-info-circle color-white" data-toggle="tooltip" data-placement="top" title="OMIM morbid map"></i></div>Morbid',
field: 'morbid',
formatter: morbidFormatter,
cellStyle: cellFormatter,
filterControl: 'select',
filterData: 'var:choices',
searchFormatter: false,
sortable: true
},*/
{
title: '<div><i class="fas fa-info-circle color-white" data-toggle="tooltip" data-placement="top" title="DECIPHER Haploinsufficiency index. Values less than 10% predict that a gene is more likely to exhibit haploinsufficiency."></i></div>%HI',
field: 'hi',
formatter: hiFormatter,
cellStyle: cellFormatter,
filterControl: 'select',
filterData: 'var:hibin',
filterCustomSearch: checkbin,
searchFormatter: false,
sortable: true
},
{
title: '<div><i class="fas fa-info-circle color-white" data-toggle="tooltip" data-placement="top" title="gnomAD v4.0 pLI score. Values greater than or equal to 0.9 indicate that a gene appears to be intolerant of loss of function variation."></i></div>pLI',
field: 'pli',
formatter: pliFormatter,
cellStyle: cellFormatter,
filterControl: 'select',
filterData: 'var:plibin',
filterCustomSearch: checkpli,
searchFormatter: false,
sortable: true
},
{
title: '<div><i class="fas fa-info-circle color-white" data-toggle="tooltip" data-placement="top" title="gnomAD v4.0 predicted loss-of-function. Values less than 0.6 indicate that a gene appears to be intolerant of loss of function variation."></i></div>LOEUF',
field: 'plof',
formatter: plofFormatter,
cellStyle: cellFormatter,
filterControl: 'select',
filterData: 'var:plofbin',
filterCustomSearch: checkplof,
searchFormatter: false,
sortable: true
},
{
field: 'date',
title: 'Last<div>Evaluated Date</div>',
formatter: reportFormatter,
cellStyle: cellFormatter,
filterControl: 'input',
searchFormatter: false,
sortName: 'rawdate',
sortable: true,
}
]
});
$table.on('load-error.bs.table', function (e, name, args) {
$("body").css("cursor", "default");
swal({
title: "Load Error",
text: "The system could not retrieve data from GeneGraph",
icon: "error"
});
})
$table.on('column-switch.bs.table', function (e, name, args) {
var hidden = $table.bootstrapTable('getHiddenColumns');
if (hidden.length > 0)
$('.action-hidden-columns').removeClass('hidden');
else
$('.action-hidden-columns').addClass('hidden');
});
$table.on('load-success.bs.table', function (e, name, args) {
$("body").css("cursor", "default");
window.update_addr();
if (name.hasOwnProperty('error'))
{
swal({
title: "Load Error",
text: name.error,
icon: "error"
});
}
var hidden = $table.bootstrapTable('getHiddenColumns');
if (hidden.length > 0)
$('.action-hidden-columns').removeClass('hidden');
else
$('.action-hidden-columns').addClass('hidden');
})
var html = `<!--<div class='mt-2 table-selector' style='float:left;'>
<span class="action-show-genes-btn pointer"><span class="dosage-box gene mr-1">G</span><span >Show Genes <i class="fas fa-toggle-on fa-lg action-show-genes"></i></span></span>
<span class="action-show-regions-btn pointer"><span class="dosage-box region ml-4 mr-1">R</span><span >Show Regions <i class="fas fa-toggle-on fa-lg action-show-regions"></i></span></span>
</div>-->
<div class="btn-group float-left mt-1" role="group" aria-label="...">
<button class="btn btn-success action-show-genes"><b>Genes: On</b></button>
<button class="btn btn-success action-show-regions"><b>Regions: On</b></button>
</div>
`;
$table.on('post-body.bs.table', function (e, name, args) {
$('[data-toggle="tooltip"]').tooltip();
})
/*$table.on('click-cell.bs.table', function (event, field, value, row, $obj) {
//console.log(e);
event.preventDefault();
event.stopPropagation();
event.stopImmediatePropagation();
});*/
$table.on('expand-row.bs.table', function (e, index, row, $obj) {
$obj.attr('colspan',12);
var t = $obj.closest('tr');
var stripe = t.prev().hasClass('bt-even-row');
t.addClass('dosage-row-bottom');
if (stripe)
t.addClass('bt-even-row');
else
t.addClass('bt-odd-row');
t.prev().addClass('dosage-row-top');
$obj.load( "/api/dosage/expand/" + row.hgnc_id );
return false;
})
$table.on('collapse-row.bs.table', function (e, index, row, $obj) {
$obj.closest('tr').prev().removeClass('dosage-row-top');
return false;
});
}
$(function() {
// Set cursor to busy prior to table init
$("body").css("cursor", "progress");
// initialize the table and load the data
inittable();
// make some mods to the search input field
var search = $('.fixed-table-toolbar .search input');
search.attr('placeholder', 'Search in table');
$( ".fixed-table-toolbar" ).show();
$('[data-toggle="tooltip"]').tooltip();
//$('[data-toggle="popover"]').popover();
var html = `<div class='ml-5' style='float:left; width:300px;'>
<form id="dosage-search-form" class="input-group" method="post" action="/kb/gene-dosage/region_search?rref=gXeb1Yvca">
<input type="hidden" name="_token" value="cQDtFK9v0wYGJfPmhVUB2MJPSYBLyIZD8SdCFTrx"> <div class="input-group-btn input-btn-region-prefix">
<button type="button" class="btn btn-primary dropdown-toggle" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> <span data-toggle="popover" data-trigger="hover" data-html="true" data-placement="top" data-container="body" title="Examples" data-content="<b>Cytoband:</b><br>Xp11.23<br><b>Full Coordinates:</b><br>chrX:47696301-47785026<br><b>Chromosome Only:</b><br>chrX<br><b>Start Only:</b><br>chrX:47696301<br><b>Stop Only:</b><br>chrX:-4778502"><i class="fas fa-info-circle"></i></span> <span class="action-select-text">GRCh37</span> <span class="caret"></span>
</button>
<ul class="dropdown-menu">
<li><a href="#" class="action-select-grch" data-uuid="GRCh37">GRCh37</a></li>
<li><a href="#" class="action-select-grch" data-uuid="GRCh38">GRCh38</a></li>
</ul>
<input id="select-gchr" type="hidden" name="type" value="GRCh37">
</div>
<input class="form-control search-input" name="region" type="search" placeholder="Enter cytoband or genomic coordinates" autocomplete="off">
<span class="input-group-btn">
<button class="btn btn-default" type="submit">Go!</button>
</span>
</form>
</div>
`;
$(".fixed-table-toolbar .search .input-group").attr("style","width:800px;");
$(".fixed-table-toolbar .search .input-group:first").attr("style","float:left; width:200px;");
//$(".fixed-table-toolbar .search .input-group:first").after(html);
$("button[name='filterControlSwitch']").attr('title', 'Column Search');
$("button[aria-label='Columns']").attr('title', 'Show/Hide More Columns');
$('[data-toggle="popover"]').popover();
region_listener();
$('.fixed-table-toolbar').on('change', '.toggle-all', function (e, name, args) {
var hidden = $table.bootstrapTable('getHiddenColumns');
if (hidden.length > 0)
$('.action-hidden-columns').removeClass('hidden');
else
$('.action-hidden-columns').addClass('hidden');
});
});
</script>
<script>
var mybutton = document.getElementById("clingen_top");
// When the user scrolls down 20px from the top of the document, show the button
window.onscroll = function() {scrollFunction()};
function scrollFunction() {
if (document.body.scrollTop > 20 || document.documentElement.scrollTop > 20) {
mybutton.style.display = "block";
} else {
mybutton.style.display = "none";
}
}
// When the user clicks on the button, scroll to the top of the document
function topFunction() {
document.body.scrollTop = 0;
document.documentElement.scrollTop = 0;
}
</script>
<script>
$(".action-login").click(function() {
$('#modalLogin').modal('show');
});
window.auth = 0;
</script>
<script src="/js/typeahead.js"></script>
<script>
$( ".typeQueryGene" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/genes");
$( ".inputQueryGene" ).show();
$( ".inputQueryGene .queryGene" ).show();
$( ".inputQueryDisease" ).hide();
$( ".inputQueryDisease .queryDisease" ).hide();
$( ".inputQueryDrug" ).hide();
$( ".inputQueryGeneName" ).hide();
$( ".inputQueryGene .queryGeneName" ).hide();
$( ".inputQueryDrug .queryDrug" ).hide();
$( ".inputQueryRegion" ).hide();
$( ".inputQueryRegion .queryRegion" ).hide();
$( ".typeQueryLabel").text("Gene Symbol ");
});
$( ".typeQueryGeneName" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/genes");
$( ".inputQueryGeneName" ).show();
$( ".inputQueryGene .queryGeneName" ).show();
$( ".inputQueryGene" ).hide();
$( ".inputQueryGene .queryGene" ).hide();
$( ".inputQueryDisease" ).hide();
$( ".inputQueryDisease .queryDisease" ).hide();
$( ".inputQueryDrug" ).hide();
$( ".inputQueryDrug .queryDrug" ).hide();
$( ".inputQueryRegion" ).hide();
$( ".inputQueryRegion .queryRegion" ).hide();
$( ".typeQueryLabel").text("Gene Name ");
});
$( ".typeQueryDisease" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/conditions");
$( ".inputQueryGene" ).hide();
$( ".inputQueryGene .queryGene" ).hide();
$( ".inputQueryGeneName" ).hide();
$( ".inputQueryGene .queryGeneName" ).hide();
$( ".inputQueryDisease" ).show();
$( ".inputQueryDisease .queryDisease" ).show();
$( ".inputQueryDrug" ).hide();
$( ".inputQueryDrug .queryDrug" ).hide();
$( ".inputQueryRegion" ).hide();
$( ".inputQueryRegion .queryRegion" ).hide();
$( ".typeQueryLabel").text("Disease Name ");
});
$( ".typeQueryDrug" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/drugs");
$( ".inputQueryGene" ).hide();
$( ".inputQueryGene .queryGene" ).hide();
$( ".inputQueryDisease" ).hide();
$( ".inputQueryDisease .queryDisease" ).hide();
$( ".inputQueryDrug" ).show();
$( ".inputQueryDrug .queryDrug" ).show();
$( ".inputQueryRegion" ).hide();
$( ".inputQueryRegion .queryRegion" ).hide();
$( ".typeQueryLabel").text("Drug Name ");
$( ".inputQueryGeneName" ).hide();
$( ".inputQueryGene .queryGeneName" ).hide();
});
$( ".typeQueryRegionGRCh37" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/regions");
$( ".inputQueryGene" ).hide();
$( ".inputQueryGene .queryGene" ).hide();
$( ".inputQueryDisease" ).hide();
$( ".inputQueryDisease .queryDisease" ).hide();
$( ".inputQueryDrug" ).hide();
$( ".inputQueryDrug .queryDrug" ).hide();
$( ".inputQueryRegion" ).show();
$( ".inputQueryRegion .queryRegion" ).show();
$( ".typeQueryLabel").text("GRCh37 Region ");
$( ".buildtype").val("GRCh37");
$( ".inputQueryGeneName" ).hide();
$( ".inputQueryGene .queryGeneName" ).hide();
});
$( ".typeQueryRegionGRCh38" ).click(function() {
$("#navSearchBar").attr("action", "https://search.clinicalgenome.org/kb/regions");
$( ".inputQueryGene" ).hide();
$( ".inputQueryGene .queryGene" ).hide();
$( ".inputQueryDisease" ).hide();
$( ".inputQueryDisease .queryDisease" ).hide();
$( ".inputQueryDrug" ).hide();
$( ".inputQueryDrug .queryDrug" ).hide();
$( ".inputQueryRegion" ).show();
$( ".inputQueryRegion .queryRegion" ).show();
$( ".typeQueryLabel").text("GRCh38 Region ");
$( ".buildtype").val("GRCh38");
$( ".inputQueryGeneName" ).hide();
$( ".inputQueryGene .queryGeneName" ).hide();
});
/*var term = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/kb/home.json?term=%QUERY',
wildcard: '%QUERY'
}
});*/
var term = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/api/genes/look/%QUERY',
wildcard: '%QUERY'
}
});
var termGeneName = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/api/genes/lookByName/%QUERY',
wildcard: '%QUERY'
}
});
var termGene = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/api/genes/look/%QUERY',
wildcard: '%QUERY'
}
});
var termDisease = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/api/conditions/look/%QUERY',
wildcard: '%QUERY'
}
});
var termDrug = new Bloodhound({
datumTokenizer: Bloodhound.tokenizers.obj.whitespace('label'),
queryTokenizer: Bloodhound.tokenizers.whitespace,
remote: {
url: 'https://search.clinicalgenome.org/api/drugs/look/%QUERY',
wildcard: '%QUERY'
}
});
$('.queryDisease').typeahead(null,
{
name: 'termDisease',
display: 'label',
source: termDisease,
templates: {
//header: '<h3 class="league-name">Header</h3>',
//footer: '<div class=""><i class="fas fa-check-circle" style="color: green;"></i><span class="mr-2 ml-2">Disease has been curated by ClinGen</span></div>',
empty: [
'<div class="tt-suggestion tt-selectable"><div class="list-group-item">Nothing found.</div></div>'
],/*,
header: [
'<div class="list-group search-results-dropdown">'
],*/
suggestion: function (data) {
return '<div class="ml-1 mr-1 row pl-2 tt-ui-row ' + (data.curated ? 'tt-ui-curated-on' : '') + '" style=" border-bottom:1px solid #ccc"><span class="col-sm-7 col-xs-7 pl-0 tt-ui-label">' + data.label + '<span class="tt-ui-alias"> ' + data.alias + '</span></span><span class=" col-sm-3 col-xs-5 tt-ui-curie"> ' + data.hgnc + '</span>' + (data.curated ? '<span class="badge badge-success pull-right hidden-xs small mt-1 col-sm-2 tt-ui-curated">Curated </span>' : '') + '</div>'
}
},
limit: 20,
minLength: 3,
highlight: true,
hint: false,
autoselect:true,
}).bind('typeahead:selected',function(evt,item){
window.location = item.url;
});
$('.queryGeneName').typeahead(null,
{
name: 'termGeneName',
display: 'label',
source: termGeneName,
templates: {
//header: '<h3 class="league-name">Header</h3>',
//footer: '<div class=""><i class="fas fa-check-circle" style="color: green;"></i><span class="mr-2 ml-2">Disease has been curated by ClinGen</span></div>',
empty: [
'<div class="tt-suggestion tt-selectable"><div class="list-group-item">Nothing found.</div></div>'
],/*,
header: [
'<div class="list-group search-results-dropdown">'
],*/
suggestion: function (data) {
return '<div class="ml-1 mr-1 row pl-2 tt-ui-row ' + (data.curated ? 'tt-ui-curated-on' : '') + '" style=" border-bottom:1px solid #ccc"><span class="col-sm-7 col-xs-7 pl-0 tt-ui-label">' + data.label + '<span class="tt-ui-alias"> ' + data.alias + '</span></span><span class=" col-sm-3 col-xs-5 tt-ui-curie"> ' + data.hgnc + '</span>' + (data.curated ? '<span class="badge badge-success pull-right hidden-xs small mt-1 col-sm-2 tt-ui-curated">Curated </span>' : '') + '</div>'
}
},
limit: 20,
minLength: 3,
highlight: true,
hint: false,
autoselect:true,
}).bind('typeahead:selected',function(evt,item){
window.location = item.url;
});
$('.queryGene').typeahead(null,
{
name: 'termGene',
display: 'label',
source: termGene,
templates: {
//header: '<h3 class="league-name">Header</h3>',
//footer: '<div class="bg-light text-right text-dark"><i class="fas fa-check-circle" style="color: green;"></i><span class="mr-2 ml-2">Gene has been curated by ClinGen</span></div>',
empty: [
'<div class="tt-suggestion tt-selectable"><div class="list-group-item">Nothing found.</div></div>'
],/*,
header: [
'<div class="list-group search-results-dropdown">'
],*/
suggestion: function (data) {
return '<div class="ml-1 mr-1 row pl-2 tt-ui-row ' + (data.curated ? 'tt-ui-curated-on' : '') + '" style=" border-bottom:1px solid #ccc"><span class="col-sm-7 col-xs-7 pl-0 tt-ui-label">' + data.label + '<span class="tt-ui-alias"> ' + data.alias + '</span></span><span class=" col-sm-3 col-xs-5 tt-ui-curie"> ' + data.hgnc + '</span>' + (data.curated ? '<span class="badge badge-success pull-right hidden-xs small mt-1 col-sm-2 tt-ui-curated">Curated </span>' : '') + '</div>'
}
},
limit: 20,
minLength: 3,
highlight: true,
hint: false,
autoselect:true,
}).bind('typeahead:selected',function(evt,item){
window.location = item.url;
});
$('.queryDrug').typeahead(null,
{
name: 'termDrug',
display: 'label',
source: termDrug,
templates: {
//header: '<h3 class="league-name">Header</h3>',
//footer: '<div class=""><i class="fas fa-check-circle" style="color: green;"><i><span class="mr-2 ml-2">Drug has been curated by ClinGen</span></div>',
empty: [
'<div class="tt-suggestion tt-selectable"><div class="list-group-item">Nothing found.</div></div>'
],/*,
header: [
'<div class="list-group search-results-dropdown">'
],*/
suggestion: function (data) {
return '<div class="ml-1 mr-1 row pl-2 tt-ui-row ' + (data.curated ? 'tt-ui-curated-on' : '') + '" style=" border-bottom:1px solid #ccc"><span class="col-sm-7 col-xs-7 pl-0 tt-ui-label">' + data.label + '<span class="tt-ui-alias"> ' + data.alias + '</span></span><span class=" col-sm-3 col-xs-5 tt-ui-curie"> ' + data.hgnc + '</span>' + (data.curated ? '<span class="badge badge-success pull-right hidden-xs small mt-1 col-sm-2 tt-ui-curated">Curated </span>' : '') + '</div>'
}
},
limit: 20,
minLength: 3,
highlight: true,
hint: false,
autoselect:true,
}).bind('typeahead:selected',function(evt,item){
window.location = item.url;
});
</script>
<script type="text/javascript">
// Tracking for google of the onclicks
$( ".externallink" ).on( "click", function() {
var title = $(this).attr("title");
//console.log( "externallink" );
//console.log( title );
ga('send', 'event', 'external_link', 'click', title );
});
$( ".externalresource" ).on( "click", function() {
var title = $(this).attr("title");
//console.log( "externallink" );
//console.log( title );
ga('send', 'event', 'external_resource', 'click', title );
});
$( ".watchreportclick" ).on( "click", function() {
var title = $(this).attr("title");
//console.log( "watchreportclick" );
//console.log( title );
ga('send', 'event', 'track_report_click', 'click', title );
});
$( ".watchdownloadclick" ).on( "click", function() {
var title = $(this).attr("title");
//console.log( "watchdownloadclick" );
//console.log( title );
ga('send', 'event', 'track_download_click', 'click', title );
});
</script>
</body>
</html>