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<h1 id="national-database-of-antibiotic-">National Database of Antibiotic Resistant Organisms (NDARO)</h1>
<p>Welcome to the NCBI National Database of Antibiotic Resistant Organisms (NDARO), a
collaborative, cross-agency, centralized hub for researchers to access AMR data to facilitate
real-time surveillance of pathogenic organisms.</p>
<p><img alt="Pathogen Hero" src="/core/assets/pathogens/images/pathogens-hero.jpg"/></p>
<p><strong><em>From left to right:</em></strong> <span>Multi-drug resistant <em>Salmonella enterica</em></span>, <span>kpc2 carbapenem resistance gene</span></p>
<h3 id="why-it-matters">Why it matters</h3>
<p>Antibiotics have been a staple of modern medicine's toolkit to fight illnesses, but antibiotic
treatment has become less reliable as antimicrobial resistance (AMR) has evolved in many bacterial
pathogens, causing the need for costly new treatments to be developed, while antimicrobial
resistant organisms continue to take thousands of lives per year. AMR is a growing concern that
affects a wide variety of people, including those within the medical community, public health
officials, food producers, pharmaceutical develops, and the general public.</p>
<h3 id="what-we-do">What we do</h3>
<p>In response to the rising threat of AMR, the White House developed the <a href="https://obamawhitehouse.archives.gov/blog/2015/03/27/our-plan-combat-and-prevent-antibiotic-resistant-bacteria">National Action Plan</a> for
Combating Antibiotic-Resistant Bacteria in 2015. As part of the National Action Plan, NCBI is
partnered with several outside agencies, including the FDA, CDC, USDA, WHO, PHE, and others to take
the following steps:</p>
<ul>
<li>To increase standardization, NCBI has developed and maintains a curated database of AMR genes and makes them available both as raw data and with an interactive web interface.</li>
<li>To make AMR-related data more widely available, NCBI is collecting genetic and antibiotic susceptibility data.</li>
<li>To make more effective use of bacterial genomic data, NCBI has developed AMRFinderPlus to identify AMR genes in bacterial genomes.</li>
<li>To assist researchers and public health officials, NCBI has developed the Isolate Browser and MicroBIGG-E to allow researchers to identify bacterial genomes with AMR genes.</li>
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<p>Watch our short video on NCBI Pathogen Detection and how to use some of our tools and resources. <a href="mailto:pd-help@ncbi.nlm.nih.gov">Contact Us</a></p>
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<p><a href="/pathogens/refgene/#">Browse NCBI's Pathogen Detection Reference Gene Catalog</a></p>
<p><a href="/pathogens/genehierarchy">Browse NCBI's Pathogen Detection Reference Gene Hierarchy</a></p>
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